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Three small stalagmites from Zoolithencave (southern Germany) show visible laminae, which consist of a clear and a brownish, pigmented layer pair. This potentially provides the opportunity to construct precise chronologies by counting annual laminae. The growth period of the three stalagmites was constrained by the C-14 bomb peak in the youngest part of all three stalagmites and C-14-dating of a piece of charcoal in the consolidated base part of stalagmite Zoo-rez-2. These data suggest an age of AD 1970 for the top laminae and a lower age limit of AD 1973-1682 or AD 1735-1778. Laminae were counted and their thickness determined on scanned thin sections of all stalagmites. On stalagmites Zoo-rez-1 and -2, three tracks were measured near the growth axes, each separated into three sections at prominent anchor laminae (I, II, III). Each section was replicated three times (a, b, c). For Zoo-rez-3, only one track was measured. The total number of laminae counted for Zoo-rez-1 ranges from 138 to 177, for Zoo-rez-2 from 119 to 145, and for Zoo-rez-3 from 159 to 166. The numbers agree well with the range constrained by the bomb peak and the age of the charcoal, which supports the annual origin of the laminae. The replicated measurements of the different tracks as well as the three different tracks on the stalagmites Zoo-rez-1 and-2 were cross-dated using the TSAP-Win (R) tree-ring software. This software is very useful for cross-dating because it enables to insert or delete missing or false laminae as well as identifying common pattern by shifting the series back and forth in time. However, visual inspection of the thin sections was necessary to confirm detection of missing or false laminae by TSAP-Win (R). For all three Zoo-rez speleothems, crossdating of the mean lamina thickness series was not possible due to a missing common pattern. The cross-dating procedure results in three refined chronologies for the three Zoo-rez stalagmites of ranging from AD 1821-1970 (Zoo-rez-1), AD 1835-1970 (Zoo-rez-2), and AD 1808-1970 (Zoo-rez-3).
Evaluation of technology-based interventions for informal caregivers of patients with dementia
(2019)
Objective: The aim of this study was to estimate the efficacy of technology-based interventions for informal caregivers of people with dementia (PWD). Methods: PubMed, PsycINFO, and Cochrane Library databases were searched in August 2018, with no restrictions in language or publication date. Two independent reviewers identified 33 eligible randomized controlled trials (RCTs) conducting a technology-based intervention for informal carers of PWD. Meta-analyses for the outcome measures caregiver depression and caregiver burden were conducted with subgroup analyses according to mode of delivery (telephone, computer/web-based, combined interventions). To assess methodologic quality, the Cochrane risk-of-bias assessment was rated. Results: Meta-analyses revealed a small but significant postintervention effect of technology-based interventions for caregiver depression and caregiver burden. Combined interventions showed the strongest effects. Conclusion: Technology-based interventions have the potential to support informal caregivers of PWD. Because of advantages such as high flexibility and availability, technology-based interventions provide a promising alternative compared with "traditional services," e.g., those for people living in rural areas. More high-quality RCTs for specific caregiver groups are needed.
Industrial production and use of boron compounds have increased during the last decades, especially for the manufacture of borosilicate glass, fiberglass, metal alloys and flame retardants. This study was conducted in two districts of Balikesir; Bandirma and Bigadic, which geographically belong to the Marmara Region of Turkey. Bandirma is the production and exportation zone for the produced boric acid and some borates and Bigadic has the largest B deposits in Turkey. 102 male workers who were occupationally exposed to boron from Bandirma and 110 workers who were occupationally and environmentally exposed to boron from Bigadic participated to our study. In this study the DNA damage in the sperm, blood and buccal cells of 212 males was evaluated by comet and micronucleus assays. No significant increase in the DNA damage in blood, sperm and buccal cells was observed in the residents exposed to boron both occupationally and environmentally (p = 0.861) for Comet test in the sperm samples, p = 0.116 for Comet test in the lymphocyte samples, p = 0.042 for micronucleus (MN) test, p = 0.955 for binucleated cells (BN), p = 1.486 for condensed chromatin (CC), p = 0.455 for karyorrhectic cells (KHC), p = 0.541 for karyolitic cells (KLY), p = 1.057 for pyknotic cells (PHC), p = 0.331 for nuclear bud (NBUD)). No correlations were seen between blood boron levels and tail intensity values of the sperm samples, lymphocyte samples, frequencies of MN, BN, KHC, KYL, PHC and NBUD. The results of this study came to the same conclusions of the previous studies that boron does not induce DNA damage even under extreme exposure conditions.
We develop an amplitude spectral ratio method for event couples from clustered earthquakes to estimate seismic wave attenuation (Q-1) in the source volume. The method allows to study attenuation within the source region of earthquake swarms or aftershocks at depth, independent of wave path and attenuation between source region and surface station. We exploit the high-frequency slope of phase spectra using multitaper spectral estimates. The method is tested using simulated full wave-field seismograms affected by recorded noise and finite source rupture. The synthetic tests verify the approach and show that solutions are independent of focal mechanisms but also show that seismic noise may broaden the scatter of results. We apply the event couple spectral ratio method to northwest Bohemia, Czech Republic, a region characterized by the persistent occurrence of earthquake swarms in a confined source region at mid-crustal depth. Our method indicates a strong anomaly of high attenuation in the source region of the swarm with an averaged attenuation factor of Qp < 100. The application to S phases fails due to scattered P-phase energy interfering with S phases. The Qp anomaly supports the common hypothesis of highly fractured and fluid saturated rocks in the source region of the swarms in northwest Bohemia. However, high temperatures in a small volume around the swarms cannot be excluded to explain our observations.
The duration of quasar accretion episodes is a key quantity for distinguishing between models for the formation and growth of supermassive black holes, the evolution of quasars, and their potential feedback effects on their host galaxies. However, this critical time-scale, often referred to as the quasar lifetime, is still uncertain by orders of magnitude (tQ≃0.01Myr−1Gyr). Absorption spectra of quasars exhibiting transmission in the He II Ly α forest provide a unique opportunity to make precise measurements of the quasar lifetime. Indeed, the size of a quasar’s He II proximity zone, the region near the quasar where its own radiation dramatically alters the ionization state of the surrounding intergalactic medium (IGM), depends sensitively on its lifetime for tQ≲30Myr, comparable to the expected e-folding time-scale for SMBH growth tS=45Myr. In this study, we compare the sizes of He II proximity zones in the Hubble Space Telescope (HST) spectra of six z ∼ 4 quasars to theoretical models generated by post-processing cosmological hydrodynamical simulations with a 1D radiative transfer algorithm. We introduce a Bayesian statistical method to infer the lifetimes of individual quasars which allows us to fully marginalize over the unknown ionization state of the surrounding IGM. We measure lifetimes 0.63+0.82−0.40 Myr and 5.75+4.72−2.74 Myr for two objects. For the other four quasars, large redshift uncertainties undermine our sensitivity allowing us to only place upper or lower limits. However, a joint analysis of these four systems yields a measurement of their average lifetime of ⟨tQ⟩=1.17+1.77−0.84 Myr. We discuss our short ∼1Myr inferred lifetimes in the context of other quasar lifetime constraints and the growth of SMBHs.
Diatoms outcompete other phytoplankton for nitrate, yet little is known about the mechanisms underpinning this ability. Genomes and genome-enabled studies have shown that diatoms possess unique features of nitrogen metabolism however, the implications for nutrient utilization and growth are poorly understood. Using a combination of transcriptomics, proteomics, metabolomics, fluxomics, and flux balance analysis to examine short-term shifts in nitrogen utilization in the model pennate diatom in Phaeodactylum tricornutum, we obtained a systems-level understanding of assimilation and intracellular distribution of nitrogen. Chloroplasts and mitochondria are energetically integrated at the critical intersection of carbon and nitrogen metabolism in diatoms. Pathways involved in this integration are organelle-localized GS-GOGAT cycles, aspartate and alanine systems for amino moiety exchange, and a split-organelle arginine biosynthesis pathway that clarifies the role of the diatom urea cycle. This unique configuration allows diatoms to efficiently adjust to changing nitrogen status, conferring an ecological advantage over other phytoplankton taxa.
Evolution of Large-Scale Magnetic Fields From Near-Earth Space During the Last 11 Solar Cycles
(2019)
We use hourly mean magnetic field measurements from 34 midlatitude geomagnetic observatories between 1900 and 2015 to investigate the long-term evolution and driving mechanism of the large-scale external magnetic field at ground. The Hourly Magnetospheric Currents index (HMC) is derived as a refinement of the Annual Magnetospheric Currents index (HMC, Pick & Korte, 2017, https://doi.org/10.1093/gji/ggx367). HMC requires an extensive revision of the observatory hourly means. It depends on three third party geomagnetic field models used to eliminate the core, the crustal, and the ionospheric solar-quiet field contributions. We mitigate the dependency of HMC on the core field model by subtracting only nondipolar components of the model from the data. The separation of the residual (dipolar) signal into internal and external (HMC) parts is the main methodological challenge. Observatory crustal biases are updated with respect to AMC, and the solar-quiet field estimation is extended to the past based on a reconstruction of solar radio flux (F10.7). We find that HMC has more power at low frequencies (periods = 1 year) than the Dcx index, especially at periods relevant to the solar cycle. Most of the slow variations in HMC can be explained by the open solar magnetic flux. There is a weakly decreasing linear trend in absolute HMC from 1900 to present, which depends sensitively on the data rejection criteria at early years. HMC is well suited for studying long-term variations of the geomagnetic field.
Degradation of thermal barrier coatings (TBCs) in gas-turbine engines due to calcium-magnesium-aluminosilicate (CMAS) glassy deposits from various sources has been a persistent issue since many years. In this study, state of the art electron microscopy was correlated with X-ray refraction techniques to elucidate the intrusion of CMAS into the porous structure of atmospheric plasma sprayed (APS) TBCs and the formation and growth of cracks under thermal cycling in a burner rig. Results indicate that the sparse nature of the infiltration as well as kinetics in the burner rig are majorly influenced by the wetting behavior of the CMAS. Despite the obvious attack of CMAS on grain boundaries, the interaction of yttria-stabilized zirconia (YSZ) with intruded CMAS has no immediate impact on structure and density of internal surfaces. At a later stage the formation of horizontal cracks is observed in a wider zone of the TBC layer.
Determinations of the ultraviolet (UV) luminosity function of active galactic nuclei (AGN) at high redshifts are important for constraining the AGN contribution to reionization and understanding the growth of supermassive black holes. Recent inferences of the luminosity function suffer from inconsistencies arising from inhomogeneous selection and analysis of data. We address this problem by constructing a sample of more than 80 000 colour-selected AGN from redshift z= 0 to 7.5 using multiple data sets homogenized to identical cosmologies, intrinsic AGN spectra, and magnitude systems. Using this sample, we derive the AGN UV luminosity function from redshift z= 0 to 7.5. The luminosity function has a double power-law form at all redshifts. The break magnitude M-* shows a steep brightening from M-* similar to -24 at z = 0.7 to M-* similar to -29 at z = 6. The faint-end slope beta significantly steepens from -1.9 at z < 2.2 to -2.4 at z similar or equal to 6. In spite of this steepening, the contribution of AGN to the hydrogen photoionization rate at z similar to 6 is subdominant (< 3 per cent), although it can be non-negligible (similar to 10 per cent) if these luminosity functions hold down to M-1450 = -18. Under reasonable assumptions, AGN can reionize He II by redshift z = 2.9. At low redshifts (z < 0.5), AGN can produce about half of the hydrogen photoionization rate inferred from the statistics of HI absorption lines in the intergalactic medium. Our analysis also reveals important systematic errors in the data, which need to be addressed and incorporated in the AGN selection function in future in order to improve our results. We make various fitting functions, codes, and data publicly available.