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- Fokker-Planck equation (5)
- Food quality (5)
- Geomagnetic field (5)
- Geomorphology (5)
- Geostatistics (5)
- Geschichte (5)
- Grassland (5)
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- ISM: jets and outflows (5)
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- Imaging (5)
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- Kant (5)
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- Learning (5)
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- Modeling (5)
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- Monsoon (5)
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- Neural networks (5)
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- Norway (5)
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- Pavlovian-to-instrumental transfer (5)
- Philosophie (5)
- Phytoplankton (5)
- Plant functional types (5)
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- Pyrenees (5)
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- Return to work (5)
- Review (5)
- Ruthenium (5)
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- Scattering (5)
- School (5)
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- Self-regulation (5)
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- Sentence reading (5)
- Sexual scripts (5)
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- Simulation (5)
- Soil erosion (5)
- Solanaceae (5)
- Solanum lycopersicum (5)
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- Ti-6Al-4V (5)
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- Twitter (5)
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- Walking (5)
- Word frequency (5)
- Workplace (5)
- X-ray diffraction (5)
- Zinc (5)
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- adipose tissue (5)
- age (5)
- aggregation (5)
- algae (5)
- algorithms (5)
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- amygdala (5)
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- anthracenes (5)
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- bicameralism (5)
- biomechanics (5)
- cAMP (5)
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- characteristics (5)
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- child (5)
- chromatin (5)
- climate change adaptation (5)
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- comets: general (5)
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- contrast (5)
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- coordination (5)
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- cytokines (5)
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- databases (5)
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- degradation (5)
- density (5)
- dietary patterns (5)
- discrepancy principle (5)
- disease (5)
- dissociative electron attachment (5)
- disturbance (5)
- ecosystems (5)
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- electrons (5)
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- elementary particles (5)
- emotions (5)
- ensemble Kalman filter (5)
- enzymes (5)
- executive functions (5)
- expertise (5)
- expression (5)
- extreme events (5)
- first passage (5)
- floodplain (5)
- food web (5)
- foraging (5)
- fractional Brownian motion (5)
- function (5)
- galaxies: haloes (5)
- galaxies: halos (5)
- galaxies: nuclei (5)
- gamma-rays: general (5)
- gender differences (5)
- gene-expression (5)
- geometric Brownian motion (5)
- giving-up density (5)
- globular clusters: general (5)
- grazing (5)
- heart (5)
- heat stress (5)
- height (5)
- herbivory (5)
- heterocycles (5)
- history (5)
- human physical conditioning (5)
- hybrid materials (5)
- hybridization (5)
- hydrogels (5)
- hypertension (5)
- identification (5)
- image processing (5)
- immobilization (5)
- infants (5)
- infrared: stars (5)
- injury risk (5)
- institutional design (5)
- insula (5)
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- inversion (5)
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- proteins (5)
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- reanalysis (5)
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- recombination (5)
- reflection (5)
- refugees (5)
- restoration (5)
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- risk perception (5)
- rotation (5)
- saccades (5)
- scale development (5)
- scattering (5)
- self-esteem (5)
- self-regulation (5)
- sensors (5)
- silver nanoparticles (5)
- skills (5)
- social support (5)
- sodium (5)
- spatial-numerical associations (5)
- speciation (5)
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- stars: chemically peculiar (5)
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- traits (5)
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- wh-questions (5)
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- 3D point clouds (4)
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- 4 (4)
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- Correlation (4)
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- Eye movement (4)
- Eye-movement monitoring (4)
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- Fire-bellied toad (4)
- Floods (4)
- Flow cytometry (4)
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- Forest management (4)
- France (4)
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- Fremdsprachenunterricht (4)
- Fuzzy logic (4)
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- IR-MALDI (4)
- ISM: magnetic fields (4)
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- Innovation (4)
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- Model (4)
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- Phase transitions (4)
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- Poecilia mexicana (4)
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- Postural control (4)
- Predictors (4)
- Prevalence (4)
- Privacy (4)
- Probabilistic forecasting (4)
- Professionswissen (4)
- Pseudo-differential operators (4)
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- R&D (4)
- RAFT polymerization (4)
- Reading development (4)
- Reading strategies (4)
- Religion (4)
- Rentenversicherung (4)
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- Risk assessment (4)
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- SDS-PAGE (4)
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- Salivary gland (4)
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- Solar cells (4)
- Species richness (4)
- Staphylococcus aureus (4)
- Start-up subsidies (4)
- Statistical methods (4)
- Structural geology (4)
- Surface roughness (4)
- Surface waves and free oscillations (4)
- Survey (4)
- Synthesis (4)
- TAVI (4)
- TRMM (4)
- TSNMRS (4)
- Tacitus (4)
- Tarim Basin (4)
- Teacher motivation (4)
- Teacher self-efficacy (4)
- Teacher training (4)
- Telerehabilitation (4)
- TerraceM (4)
- Thermochronology (4)
- Thermoresponsive (4)
- Thin film (4)
- Tian Shan (4)
- Tien Shan (4)
- ToF-SIMS (4)
- Transfer (4)
- Transformation (4)
- Translation (4)
- Triassic (4)
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- Trust (4)
- Tso Moriri Lake (4)
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- Validity (4)
- Van Allen Probes (4)
- Vegetation change (4)
- WA-PLS (4)
- Weltbewusstsein (4)
- Work ability (4)
- X-ray absorption (4)
- X-ray photoelectron spectroscopy (4)
- X-ray scattering (4)
- XPS (4)
- academic self-concept (4)
- acceleration (4)
- acceptance (4)
- accretion, accretion disks (4)
- acid ceramidase (4)
- agency (4)
- alexithymia (4)
- alternatives (4)
- anger (4)
- anthropology (4)
- anthropometry (4)
- antibody (4)
- antioxidants (4)
- antiplasmodial (4)
- apoptosis (4)
- arithmetic (4)
- atomic force microscopy (4)
- attitude (4)
- attitudes (4)
- augmented reality (4)
- authoritarianism (4)
- autonomy (4)
- auxin (4)
- big data (4)
- biofilm (4)
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- biomarkers (4)
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- birth weight (4)
- body waves (4)
- brain (4)
- capacity (4)
- carbon nitride (4)
- carbon sequestration (4)
- catchment (4)
- cell adhesion (4)
- cell-free protein synthesis (4)
- cells (4)
- cellulose (4)
- change (4)
- change of direction (4)
- chaos (4)
- chemotaxis (4)
- children and adolescents (4)
- classification (4)
- climate mitigation (4)
- clone (4)
- co-limitation (4)
- coastal erosion (4)
- cognitive development (4)
- community effect on height (4)
- composition (4)
- conflict resolution (4)
- conjugated polymers (4)
- construction (4)
- context (4)
- conversation analysis (4)
- coping (4)
- core (4)
- corpus linguistics (4)
- cue-based retrieval (4)
- cyber aggression (4)
- cyclic voltammetry (4)
- data (4)
- database (4)
- decarbonization (4)
- decentralization (4)
- defense (4)
- demography (4)
- deposition (4)
- depressive symptoms (4)
- diagnostics (4)
- dialogue (4)
- domestication (4)
- drop jump (4)
- droughts (4)
- dynamic NMR (4)
- dyslexia (4)
- dysphagia (4)
- early warning (4)
- eating behavior (4)
- ecohydrology (4)
- ecology (4)
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- eicosapentaenoic acid (4)
- electrostatics (4)
- engagement (4)
- environmental change (4)
- eutrophication (4)
- evapotranspiration (4)
- events (4)
- executive function (4)
- eye movement (4)
- eye-movement monitoring (4)
- fNIRS (4)
- facilitation (4)
- fiction (4)
- first passage time (4)
- first-passage time (4)
- flood risk management (4)
- flooding (4)
- fluorescence correlation spectroscopy (4)
- force (4)
- freshwater (4)
- galaxies: fundamental parameters (4)
- galaxies: star formation (4)
- gelatin (4)
- genetics (4)
- geochemistry (4)
- geomorphology (4)
- global (4)
- grammar (4)
- gravitational waves (4)
- habitat (4)
- history and philosophy of astronomy (4)
- holding capacity (4)
- home range (4)
- human impact (4)
- human rights (4)
- hybridization capture (4)
- hydrogen peroxide (4)
- hydropower (4)
- hypochondriasis (4)
- income (4)
- individual (4)
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- inference (4)
- instability (4)
- integration (4)
- international organisations (4)
- isotopes (4)
- lakes (4)
- land use change (4)
- language production (4)
- large-scale structure of Universe (4)
- life history (4)
- lifespan (4)
- light (4)
- linear hypersubstitution (4)
- livestock (4)
- low-energy electrons (4)
- macrophytes (4)
- magnetostratigraphy (4)
- maturity (4)
- measurement invariance (4)
- mechanisms (4)
- membrane (4)
- memory retrieval (4)
- metabolite profiling (4)
- metacognition (4)
- microcystin (4)
- microparticles (4)
- mitochondrial DNA (4)
- modality (4)
- molecular modeling (4)
- molecular rods (4)
- molybdenum cofactor (4)
- mood (4)
- morphological processing (4)
- movement ecology (4)
- multiplicative noise (4)
- muscle (4)
- museum specimens (4)
- narcissism (4)
- natural language processing (4)
- natural products (4)
- neuroplasticity (4)
- neutrinos (4)
- new species (4)
- non-fullerene acceptors (4)
- non-state actors (4)
- nuclear envelope (4)
- nuclear lamina (4)
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- number (4)
- numerical simulations (4)
- optimal transport (4)
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- organization (4)
- organizations (4)
- orthography (4)
- oscillations (4)
- oxygen (4)
- pain (4)
- pandemic (4)
- parafoveal processing (4)
- parliamentary government (4)
- partial clone (4)
- partial melting (4)
- participation (4)
- participatory research (4)
- patterns (4)
- periodization (4)
- peroxides (4)
- perpetration (4)
- phase transitions (4)
- phenotyping (4)
- phosphate (4)
- photocatalysis (4)
- photophysics (4)
- photosynthesis (4)
- physiology (4)
- phytolith (4)
- picture-word interference (4)
- piezoelectricity (4)
- plankton (4)
- planning (4)
- plant functional traits (4)
- plant population and community dynamics (4)
- plasmonics (4)
- platelets (4)
- pneumonia (4)
- policy (4)
- politeness (4)
- political equality (4)
- poly(ethylene glycol) (4)
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- polystyrene (4)
- porosity (4)
- porous carbon (4)
- pragmatics (4)
- predator-prey dynamics (4)
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- principal component analysis (4)
- privacy (4)
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- properties (4)
- prosocial behavior (4)
- prosodic boundary cues (4)
- protein-protein interaction (4)
- proteomics (4)
- quantum dots (4)
- reconstruction (4)
- rejection sensitivity (4)
- relational aggression (4)
- religion (4)
- repetition (4)
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- resource competition (4)
- resources (4)
- respiration (4)
- responses (4)
- retinol (4)
- retinol-binding protein 4 (4)
- return to work (4)
- rheology (4)
- river incision (4)
- rotifers (4)
- salicylic acid (4)
- salt stress (4)
- school children (4)
- second language (4)
- seismicity (4)
- selection (4)
- self-healing (4)
- semantics (4)
- semi-arid (4)
- sensitivity analysis (4)
- sentence production (4)
- sex (4)
- shape memory (4)
- sharing economy (4)
- shrub encroachment (4)
- silicon (4)
- simulations (4)
- site effects (4)
- snow (4)
- soccer (4)
- social cognition (4)
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- soil (4)
- soil erosion (4)
- solar cells (4)
- sorption (4)
- speed (4)
- standardization (4)
- starch phosphorylation (4)
- stars: black holes (4)
- stars: low-mass (4)
- stars: oscillations (4)
- starspots (4)
- stochastic models (4)
- stochastic resetting (4)
- strategic growth adjustments (4)
- stroke (4)
- structure elucidation (4)
- supernovae: general (4)
- surface (4)
- surface modification (4)
- surface-enhanced Raman scattering (4)
- surveillance (4)
- suspended sediment (4)
- sustainable development (4)
- systems biology (4)
- tailspike protein (4)
- teaching quality (4)
- thaliana (4)
- therapy (4)
- thermal (4)
- thermoresponsive polymers (4)
- time series (4)
- tracking (4)
- training adaptation (4)
- transcriptional memory (4)
- transcriptome (4)
- transition (4)
- transport (4)
- trunk (4)
- tundra (4)
- type 2 diabetes mellitus (4)
- uncertainty quantification (4)
- uplift (4)
- usability (4)
- visions of democracy (4)
- voltage losses (4)
- water balance (4)
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- weight loss (4)
- wetland (4)
- wh-in-situ (4)
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- workplace (4)
- world literature (4)
- yellow flags (4)
- young adults (4)
- zebrafish (4)
- 19. Jahrhundert (3)
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- (Anti)aromaticity (2)
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- acidophile (2)
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- dictyostelium (2)
- dielectric (2)
- dielectric barrier discharge (DBD) (2)
- dielectric barrier discharges (2)
- dielectric properties (2)
- dielectric spectroscopy (2)
- dielectrophoresis (2)
- dienes (2)
- diet (2)
- differentiation (2)
- diffraction (2)
- diffusing diffusivity (2)
- digital (2)
- digital elevation model (2)
- digital health app (2)
- digital rock physics (2)
- digital technologies (2)
- digital therapy (2)
- digitalisation (2)
- dimerization (2)
- disability-adjusted life years (2)
- discharge (2)
- discourse production (2)
- disease severity (2)
- dispersion (2)
- disposition (2)
- distance scale (2)
- distress (2)
- divergence (2)
- diversity climate (2)
- division of labor (2)
- division of labour (2)
- dog (2)
- dopamine (2)
- drainage networks (2)
- drainage of the catchment area (2)
- driving force (2)
- dropout (2)
- drought intensity (2)
- drought projections (2)
- drug control (2)
- drug delivery system (2)
- drug metabolism (2)
- drug monitoring (2)
- drugs (2)
- drylands (2)
- dual GLP-1/glucagon receptor agonist (2)
- duration (2)
- dwarfs galaxies (2)
- dyadic coping (2)
- dye removal (2)
- dyes (2)
- dyes/pigments (2)
- dynamic light scattering (2)
- dynamic loading (2)
- dynamic models (2)
- dynamic programming (2)
- dynamical model (2)
- dysfunction (2)
- e-government (2)
- eDNA (2)
- eHealth (2)
- eNOS (2)
- early Universe (2)
- early stopping (2)
- earthquake hydrology (2)
- earthquake source (2)
- earthquake source observations (2)
- eccentric training (2)
- echocardiography (2)
- echolocation (2)
- eclogite (2)
- ecoevolutionary dynamics (2)
- ecological momentary assessment (2)
- econometrics (2)
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- ecosystem function (2)
- ecosystem processes (2)
- edge-driven convection (2)
- effectors (2)
- effects (2)
- efficient (2)
- efficient method (2)
- elastic properties (2)
- elastomers (2)
- elbow breadth (2)
- elections (2)
- electoral systems (2)
- electric fish (2)
- electrical resistivity (2)
- electroactive polymer (2)
- electrodes (2)
- electroencephalography (2)
- electromagnetic radiation (2)
- electron microscopy (2)
- electron-transfer (2)
- electropolymerization (2)
- elemental composition (2)
- elementary school (2)
- elevated plus-maze (2)
- elite athlete (2)
- emergency (2)
- emergency management (2)
- emotion recognition (2)
- emotion regulation (2)
- employment services (2)
- empowerment (2)
- encoding (2)
- end-stage kidney disease (2)
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- enhancement (2)
- ensemble prediction (2)
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- enzyme (2)
- enzyme immobilization (2)
- eolian dust (2)
- epidermis (2)
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- equation (2)
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- explosives (2)
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- extracellular matrix (2)
- extraction (2)
- extremophile (2)
- extremophiles (2)
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- eye-voice span (2)
- face (2)
- facies (2)
- factor analysis (2)
- factor structure (2)
- fatty acid (2)
- fatty-acids (2)
- fault creep (2)
- features (2)
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- fibers (2)
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- field-aligned currents (2)
- fields (2)
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- first language acquisition (2)
- first stars (2)
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- flavanonol (2)
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- flood (2)
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- flood risk analysis (2)
- floodplain sedimentation (2)
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- flowering time (2)
- fluctuation-dissipation theorem (2)
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- fluid-induced seismicity (2)
- fluid-rock interaction (2)
- fluids (2)
- fluorescence lifetime (2)
- fluorescent dyes (2)
- fluoroethylenepropylene (FEP) copolymer (2)
- fluvial geomorphology (2)
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- flux (2)
- focus realization (2)
- follower turnover intentions (2)
- food neophilia (2)
- food preference (2)
- food preferences (2)
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- frequency (2)
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- functional (2)
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- functions (2)
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- fuzzy logic (2)
- gait analysis (2)
- galaxies (2)
- galaxies: clusters: general (2)
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- galaxies: individual: Small Magellanic Cloud (2)
- galaxies: magnetic fields (2)
- galaxies: star clusters: general (2)
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- gels (2)
- gender gap (2)
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- genealogy (2)
- general practitioners (2)
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- gibberellic acid (2)
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- glucocorticoid receptor (2)
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- glutathione (2)
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- grouping (2)
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- hydrolysis (2)
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- in situ (2)
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- in-situ (2)
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- induced pluripotent stem cells (2)
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- information integration (2)
- information technology (2)
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- infrared thermography (2)
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- inorganic carbon uptake kinetics (2)
- input frequency (2)
- insect (2)
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- institutional interplay (2)
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- ion exchange (2)
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- ionospheric precursors of earthquakes (2)
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- isotopic tiling theory (2)
- iterative regularization (2)
- jasmonic acid (2)
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- jumps (2)
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- kana (2)
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- ketones (2)
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- kidney (2)
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- kinetic instabilities (2)
- kink-like instability (2)
- knee (2)
- knee joint angle (2)
- knickpoints (2)
- knowledge management (2)
- knowledge sharing (2)
- kommunale Demokratie (2)
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- lactate threshold (2)
- lactones (2)
- land cover change (2)
- land management (2)
- land-use (2)
- landscape connectivity (2)
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- language and aging (2)
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- lutherische Theologie (2)
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- miscellaneous (2)
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- mitochondrial dysfunction (2)
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- mitogenome (2)
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- moderne jüdische Geschichte (2)
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- monomers (2)
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- n-Alkanes (2)
- naming (2)
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- overreaching (2)
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- phosphatidylserine (2)
- phosphorylase (2)
- phosphorylation (2)
- photochromism (2)
- photoelectron (2)
- photogrammetry (2)
- photoisomerization (2)
- photoluminescence quenching (2)
- photon density wave spectroscopy (2)
- photonic crystals (2)
- photoswitches (2)
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- phytoplankton communities (2)
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- pitch angle (2)
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- planets and satellites: fundamental parameters (2)
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- plant cell wall (2)
- plant invasions (2)
- plant species richness (2)
- plant volatiles (2)
- plant-soil (belowground) interactions (2)
- plasma instabilities (2)
- plasmaspheric hiss (2)
- plateau (2)
- platform (2)
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- plausibility (2)
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- pluvial floods (2)
- plyometric exercise (2)
- plyometrics (2)
- point clouds (2)
- polarity (2)
- policy advice (2)
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- political elites (2)
- political ideology (2)
- political philosophy (2)
- politische Eliten (2)
- politische Ideologie (2)
- pollinator shift (2)
- poly(epsilon-caprolactone) (2)
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- porous silicon (2)
- positioning (2)
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- potassium channel (2)
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- pulling isometric muscle action (PIMA) (2)
- pulsars: individual: PSR B0833-45 (2)
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Institute
- Institut für Physik und Astronomie (4104)
- Institut für Biochemie und Biologie (3749)
- Institut für Geowissenschaften (2791)
- Institut für Chemie (2404)
- Department Psychologie (1753)
- Institut für Romanistik (1127)
- Wirtschaftswissenschaften (1110)
- Historisches Institut (1050)
- Institut für Mathematik (1049)
- Sozialwissenschaften (1031)
The bimolecular recombination characteristics of conjugated polymer poly[(4,4'-bis(2-ethylhexyl)dithieno[3,2-b:2',3'-d]silole)-2,6-diyl-alt-(2,5-bis 3-tetradecylthiophen-2-y1 thiazolo 5,4-d thiazole)-2,5diy1] (PDTSiTTz) blended with the fullerene series PC60BM, ICMA, ICBA, and ICTA have been investigated using microsecond and femtosecond transient absorption spectroscopy, in conjunction with electroluminescence measurements and ambient photoemission spectroscopy. The non-Langevin polymer PDTSiTTz allows an inspection of intrinsic bimolecular recombination rates uninhibited by diffusion, while the low oscillator strengths of fullerenes allow polymer features to dominate, and we compare our results to those of the well-known polymer Si-PCPDTBT. Using mu s-TAS, we have shown that the trap -limited decay dynamics of the PDTSiTTz polaron becomes progressively slower across the fullerene series, while those of Si-PCPDTBT are invariant. Electroluminescence measurements showed an unusual double peak in pristine PDTSiTTz, attributed to a low energy intragap charge transfer state, likely interchain in nature. Furthermore, while the pristine PDTSiTTz showed a broad, low-intensity density of states, the ICBA and ICTA blends presented a virtually identical DOS to Si-PCPDTBT and its blends. This has been attributed to a shift from a delocalized, interchain highest occupied molecular orbital (HOMO) in the pristine material to a dithienosilole-centered HOMO in the blends, likely a result of the bulky fullerenes increasing interchain separation. This HOMO localization had a side effect of progressively shifting the polymer HOMO to shallower energies, which was correlated with the observed decrease in bimolecular recombination rate and increased "trap" depth. However, since the density of tail states remained the same, this suggests that the traditional viewpoint of "trapping" being dominated by tail states may not encompass the full picture and that the breadth of the DOS may also have a strong influence on bimolecular recombination.
Understanding and constraining the source of geodetic deformation in volcanic areas is an important component of hazard assessment. Here, we analyse deformation and seismicity for one year before the March 2021 Fagradalsfjall eruption in Iceland. We generate a high-resolution catalogue of 39,500 earthquakes using optical cable recordings and develop a poroelastic model to describe three pre-eruptional uplift and subsidence cycles at the Svartsengi geothermal field, 8 km west of the eruption site. We find the observed deformation is best explained by cyclic intrusions into a permeable aquifer by a fluid injected at 4 km depth below the geothermal field, with a total volume of 0.11 ± 0.05 km3 and a density of 850 ± 350 kg m–3. We therefore suggest that ingression of magmatic CO2 can explain the geodetic, gravity and seismic data, although some contribution of magma cannot be excluded.
The Palaeocene-Eocene Thermal Maximum (ca. 56 million years ago) offers a primary analogue for future global warming and carbon cycle recovery. Yet, where and how massive carbon emissions were mitigated during this climate warming event remains largely unknown. Here we show that organic carbon burial in the vast epicontinental seaways that extended over Eurasia provided a major carbon sink during the Palaeocene-Eocene Thermal Maximum. We coupled new and existing stratigraphic analyses to a detailed paleogeographic framework and using spatiotemporal interpolation calculated ca. 720–1300 Gt organic carbon excess burial, focused in the eastern parts of the Eurasian epicontinental seaways. A much larger amount (2160–3900 Gt C, and when accounting for the increase in inundated shelf area 7400–10300 Gt C) could have been sequestered in similar environments globally. With the disappearance of most epicontinental seas since the Oligocene-Miocene, an effective negative carbon cycle feedback also disappeared making the modern carbon cycle critically dependent on the slower silicate weathering feedback.
Many geophysical inverse problems are known to be ill-posed and, thus, requiring some kind of regularization in order to provide a unique and stable solution. A possible approach to overcome the inversion ill-posedness consists in constraining the position of the model interfaces. For a grid-based parameterization, such a structurally constrained inversion can be implemented by adopting the usual smooth regularization scheme in which the local weight of the regularization is reduced where an interface is expected. By doing so, sharp contrasts are promoted at interface locations while standard smoothness constraints keep affecting the other regions of the model. In this work, we present a structurally constrained approach and test it on the inversion of frequency-domain electromagnetic induction (FD-EMI) data using a regularization approach based on the Minimum Gradient Support stabilizer, which is capable to promote sharp transitions everywhere in the model, i.e., also in areas where no structural a prioriinformation is available. Using 1D and 2D synthetic data examples, we compare the proposed approach to a structurally constrained smooth inversion as well as to more standard (i.e., not structurally constrained) smooth and sharp inversions. Our results demonstrate that the proposed approach helps in finding a better and more reliable reconstruction of the subsurface electrical conductivity distribution, including its structural characteristics. Furthermore, we demonstrate that it allows to promote sharp parameter variations in areas where no structural information are available. Lastly, we apply our structurally constrained scheme to FD-EMI field data collected at a field site in Eastern Germany to image the thickness of peat deposits along two selected profiles. In this field example, we use collocated constant offset ground-penetrating radar (GPR) data to derive structural a priori information to constrain the inversion of the FD-EMI data. The results of this case study demonstrate the effectiveness and flexibility of the proposed approach.
The use of automated tools to reconstruct lipid metabolic pathways is not warranted in plants. Here, the authors construct Plant Lipid Module for Arabidopsis rosette using constraint-based modeling, demonstrate its integration in other plant metabolic models, and use it to dissect the genetic architecture of lipid metabolism.
Lipids play fundamental roles in regulating agronomically important traits. Advances in plant lipid metabolism have until recently largely been based on reductionist approaches, although modulation of its components can have system-wide effects. However, existing models of plant lipid metabolism provide lumped representations, hindering detailed study of component modulation. Here, we present the Plant Lipid Module (PLM) which provides a mechanistic description of lipid metabolism in the Arabidopsis thaliana rosette. We demonstrate that the PLM can be readily integrated in models of A. thaliana Col-0 metabolism, yielding accurate predictions (83%) of single lethal knock-outs and 75% concordance between measured transcript and predicted flux changes under extended darkness. Genome-wide associations with fluxes obtained by integrating the PLM in diel condition- and accession-specific models identify up to 65 candidate genes modulating A. thaliana lipid metabolism. Using mutant lines, we validate up to 40% of the candidates, paving the way for identification of metabolic gene function based on models capturing natural variability in metabolism.
An earthquake swarm affected the Bransfield Strait, Antarctica, a unique rift basin in transition from intra-arc rifting to ocean spreading. The swarm, counting similar to 85,000 volcano-tectonic earthquakes since August 2020, is located close to the Orca submarine volcano, previously considered inactive. Simultaneously, geodetic data reported up to similar to 11 cm north-westward displacement over King George Island. We use a broad variety of geophysical data and methods to reveal the complex migration of seismicity, accompanying the intrusion of 0.26-0.56 km(3) of magma. Strike-slip earthquakes mark the intrusion at depth, while shallower normal faulting the similar to 20 km long lateral growth of a dike. Seismicity abruptly decreased after a Mw 6.0 earthquake, suggesting the magmatic dike lost pressure with the slipping of a large fault. A seafloor eruption is likely, but not confirmed by sea surface temperature anomalies. The unrest documents episodic magmatic intrusion in the Bransfield Strait, providing unique insights into active continental rifting.
The prevalence of obesity in the pediatric population has become a major public health issue. Indeed, the dramatic increase of this epidemic causes multiple and harmful consequences, Physical activity, particularly physical exercise, remains to be the cornerstone of interventions against childhood obesity. Given the conflicting findings with reference to the relevant literature addressing the effects of exercise on adiposity and physical fitness outcomes in obese children and adolescents, the effect of duration-matched concurrent training (CT) [50% resistance (RT) and 50% high-intensity-interval-training (HIIT)] on body composition and physical fitness in obese youth remains to be elucidated. Thus, the purpose of this study was to examine the effects of 9-weeks of CT compared to RT or HIIT alone, on body composition and selected physical fitness components in healthy sedentary obese youth. Out of 73 participants, only 37; [14 males and 23 females; age 13.4 +/- 0.9 years; body-mass-index (BMI): 31.2 +/- 4.8 kg center dot m-2] were eligible and randomized into three groups: HIIT (n = 12): 3-4 setsx12 runs at 80-110% peak velocity, with 10-s passive recovery between bouts; RT (n = 12): 6 exercises; 3-4 sets x 10 repetition maximum (RM) and CT (n = 13): 50% serial completion of RT and HIIT. CT promoted significant greater gains compared to HIIT and RT on body composition (p < 0.01, d = large), 6-min-walking test distance (6 MWT-distance) and on 6 MWT-VO2max (p < 0.03, d = large). In addition, CT showed substantially greater improvements than HIIT in the medicine ball throw test (20.2 vs. 13.6%, p < 0.04, d = large). On the other hand, RT exhibited significantly greater gains in relative hand grip strength (p < 0.03, d = large) and CMJ (p < 0.01, d = large) than HIIT and CT. CT promoted greater benefits for fat, body mass loss and cardiorespiratory fitness than HIIT or RT modalities. This study provides important information for practitioners and therapists on the application of effective exercise regimes with obese youth to induce significant and beneficial body composition changes. The applied CT program and the respective programming parameters in terms of exercise intensity and volume can be used by practitioners as an effective exercise treatment to fight the pandemic overweight and obesity in youth.
Background
Teleost fishes comprise more than half of the vertebrate species. Within teleosts, most phylogenies consider the split between Osteoglossomorpha and Euteleosteomorpha/Otomorpha as basal, preceded only by the derivation of the most primitive group of teleosts, the Elopomorpha. While Osteoglossomorpha are generally species poor, the taxon contains the African weakly electric fish (Mormyroidei), which have radiated into numerous species. Within the mormyrids, the genus Campylomormyrus is mostly endemic to the Congo Basin. Campylomormyrus serves as a model to understand mechanisms of adaptive radiation and ecological speciation, especially with regard to its highly diverse species-specific electric organ discharges (EOD). Currently, there are few well-annotated genomes available for electric fish in general and mormyrids in particular. Our study aims at producing a high-quality genome assembly and to use this to examine genome evolution in relation to other teleosts. This will facilitate further understanding of the evolution of the osteoglossomorpha fish in general and of electric fish in particular.
Results
A high-quality weakly electric fish (C. compressirostris) genome was produced from a single individual with a genome size of 862 Mb, consisting of 1,497 contigs with an N50 of 1,399 kb and a GC-content of 43.69%. Gene predictions identified 34,492 protein-coding genes, which is a higher number than in the two other available Osteoglossomorpha genomes of Paramormyrops kingsleyae and Scleropages formosus. A Computational Analysis of gene Family Evolution (CAFE5) comparing 33 teleost fish genomes suggests an overall faster gene family turnover rate in Osteoglossomorpha than in Otomorpha and Euteleosteomorpha. Moreover, the ratios of expanded/contracted gene family numbers in Osteoglossomorpha are significantly higher than in the other two taxa, except for species that had undergone an additional genome duplication (Cyprinus carpio and Oncorhynchus mykiss). As potassium channel proteins are hypothesized to play a key role in EOD diversity among species, we put a special focus on them, and manually curated 16 Kv1 genes. We identified a tandem duplication in the KCNA7a gene in the genome of C. compressirostris.
Conclusions
We present the fourth genome of an electric fish and the third well-annotated genome for Osteoglossomorpha, enabling us to compare gene family evolution among major teleost lineages. Osteoglossomorpha appear to exhibit rapid gene family evolution, with more gene family expansions than contractions. The curated Kv1 gene family showed seven gene clusters, which is more than in other analyzed fish genomes outside Osteoglossomorpha. The KCNA7a, encoding for a potassium channel central for EOD production and modulation, is tandemly duplicated which may related to the diverse EOD observed among Campylomormyrus species.
Recently, there has been an upsurge of activity in image-based non-photorealistic rendering (NPR), and in particular portrait image stylisation, due to the advent of neural style transfer (NST). However, the state of performance evaluation in this field is poor, especially compared to the norms in the computer vision and machine learning communities. Unfortunately, the task of evaluating image stylisation is thus far not well defined, since it involves subjective, perceptual, and aesthetic aspects. To make progress towards a solution, this paper proposes a new structured, three-level, benchmark dataset for the evaluation of stylised portrait images. Rigorous criteria were used for its construction, and its consistency was validated by user studies. Moreover, a new methodology has been developed for evaluating portrait stylisation algorithms, which makes use of the different benchmark levels as well as annotations provided by user studies regarding the characteristics of the faces. We perform evaluation for a wide variety of image stylisation methods (both portrait-specific and general purpose, and also both traditional NPR approaches and NST) using the new benchmark dataset.
Arctic coasts are vulnerable to the effects of climate change, including rising sea levels and the loss of permafrost, sea ice and glaciers. Assessing the influence of anthropogenic warming on Arctic coastal dynamics, however, is challenged by the limited availability of observational, oceanographic and environmental data. Yet, with the majority of permafrost coasts being erosive, coupled with projected intensification of erosion and flooding, understanding these changes is critical. In this Review, we describe the morphological diversity of Arctic coasts, discuss important drivers of coastal change, explain the specific sensitivity of Arctic coasts to climate change and provide an overview of pan-Arctic shoreline change and its multifaceted impacts. Arctic coastal changes impact the human environment by threatening coastal settlements, infrastructure, cultural sites and archaeological remains. Changing sediment fluxes also impact the natural environment through carbon, nutrient and pollutant release on a magnitude that remains difficult to predict. Increasing transdisciplinary and interdisciplinary collaboration efforts will build the foundation for identifying sustainable solutions and adaptation strategies to reduce future risks for those living on, working at and visiting the rapidly changing Arctic coast.