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Sexuelle Aggression
(2006)
Geheimgeschichten
(2006)
In July 2004 the Cassini–Huygens mission reached the Saturnian system and started its orbital tour. A total of 75 orbits will be carried out during the primary mission until August 2008. In these four years Cassini crosses the ring plane 150 times and spends approx. 400 h within Titan's orbit. The Cosmic Dust Analyser (CDA) onboard Cassini characterises the dust environment with its extended E ring and embedded moons. Here, we focus on the CDA results of the first year and we present the Dust Analyser (DA) data within Titan's orbit. This paper does investigate High Rate Detector data and dust composition measurements. The authors focus on the analysis of impact rates, which were strongly variable primarily due to changes of the spacecraft pointing. An overview is given about the ring plane crossings and the DA counter measurements. The DA dust impact rates are compared with the DA boresight configuration around all ring plane crossings between June 2004 and July 2005. Dust impacts were registered at altitudes as high as 100 000 km above the ring plane at distances from Saturn between 4 and 10 Saturn radii. In those regions the dust density of particles bigger than 0.5 can reach values of 0.001m-3.
To develop and investigate detailed mathematical models of metabolic processes is one of the primary challenges in systems biology. However, despite considerable advance in the topological analysis of metabolic networks, kinetic modeling is still often severely hampered by inadequate knowledge of the enzyme-kinetic rate laws and their associated parameter values. Here we propose a method that aims to give a quantitative account of the dynamical capabilities of a metabolic system, without requiring any explicit information about the functional form of the rate equations. Our approach is based on constructing a local linear model at each point in parameter space, such that each element of the model is either directly experimentally accessible or amenable to a straightforward biochemical interpretation. This ensemble of local linear models, encompassing all possible explicit kinetic models, then allows for a statistical exploration of the comprehensive parameter space. The method is exemplified on two paradigmatic metabolic systems: the glycolytic pathway of yeast and a realistic-scale representation of the photosynthetic Calvin cycle.
We develop a model of stochastic radiation pressure for rotating non-spherical particles and apply the model to circumplanetary dynamics of dust grains. The stochastic properties of the radiation pressure are related to the ensemble-averaged characteristics of the rotating particles, which are given in terms of the rotational time-correlation function of a grain. We investigate the model analytically and show that an ensemble of particle trajectories demonstrates a diffusion-like behaviour. The analytical results are compared with numerical simulations, performed for the motion of the dusty ejecta from Deimos in orbit around Mars. We find that the theoretical predictions are in a good agreement with the simulation results. The agreement however deteriorates at later time, when the impact of non-linear terms, neglected in the analytic approach, becomes significant. Our results indicate that the stochastic modulation of the radiation pressure can play an important role in the circumplanetary dynamics of dust and may in case of some dusty systems noticeably alter an optical depth. (c) 2006 Elsevier Ltd. All rights reserved.
The mildly peraluminous granite of Seiffen, in the eastern Erzgebirge of Germany, is exposed by drillcores and associated with an abandoned Sri mine. The granite is of Stefanian age, with overlapping Th-U-total Pb monazite (302 +/- 4 Ma) and K-Ar siderophyllite ages (301 +/- 5 Ma). It is among the youngest granites in the Erzgebirge, emplaced in an extensional setting. The medium-grained, equigranular granite classifies as high-F, low-P Li-mica granite of A-type affinity. It is spatially associated with a high-Si rhyolitic microgranite, documenting the shallow intrusion level of this igneous association. Zircon, monazite-(Ce), and xenotime-(Y) constitute important radioactive accessory minerals in the granite, hosting the major proportions (> 80-90%) of the bulk-rock budgets of the REE, Y, and Th. A significant percentage of U (40-50%) may reside within unidentified phases or precipitated along grain boundaries. The most uncommon accessory phase is late-magmatic ytterbian xenotime-(Y) containing up to 11.2 wt% Yb2O3, in addition to 7.3 wt% Er2O3 and 7.9 wt% Dy2O3. The Seiffen granite (epsilon(Nd(300)) = -4.6) is geochemically evolved and rich in Sri (23-63 ppm) and W (11-14 ppm). It contains elevated to high concentrations of incompatible lithophile elements such as F, Li, Ga, Rb, Y, Nb, Cs, REE, Th, and U, thus having much in common chemically with subvolcanic ongonites. The most prominent compositional feature is the strong enrichment (in ppm) in Be (51-55) and Ta (23-28). The granite exhibits flat chondrite-normalized REE patterns (La-N/Lu-N = 1.35-1.48) and a moderate negative Eu anomaly (Eu/Eu* = 0.12-0.13). Indications for alteration-induced, postmagmatic disturbances of initial elemental abundances are weak and mainly relate to the ore-forming elements Sri and U.
The noncovalent binding of selected phenolic compounds (chlorogenic-, ferutic-, gallic acid, quercetin, rutin, and isoquercetin) to proteins (HSA, BSA, soy glycinin, and lysozyme) was studied by an indirect method applying the quenching of intrinsic tryptophan fluorescence. From the data obtained, the binding constants were calculated by nonlinear regression (one site binding; y = Bx/k + x). It has been reported that tannins inhibit human salivary amylase and that these complexes may reduce the development of cariogenic plaques. Further, amylase contains two tryptophan residues in its active site. Therefore, in a second part of the study involving 31 human subjects, evidence was sought for noncovalent interactions between the phenols of green tea and saliva proteins as measured by the fluorescence intensity. Amylase activity was determined before and after the addition of green tea to saliva of 31 subjects. Forty percent of the subjects showed an increase in amylase activity contrary to studies reporting only a decrease in activity. The interactions of tannin with amylase result in a decrease of its activity. It still remains to be elucidated why amylase does not react uniformly under conditions of applying green tea to saliva. Further, in terms of using phenols as caries inhibitors this finding should be of importance.
Plant phenolic compounds are known to interact with proteins producing changes in the food (e.g., biological value (BV), color, taste). Therefore, the in vivo relevance, especially, of covalent phenolprotein reactions on protein quality was studied in a rat bioassay. The rats were fed protein derivatives at a 10% protein level. Soy proteins were derivatized with chlorogenic acid and quercetin (derivatization levels: 0.056 and 0.28 mmol phenolic compound/gram protein). Analysis of nitrogen in diets, urine, and fecal samples as well as the distribution of amino acids were determined. Depending on the degree of derivatization, the rats fed with soy protein derivatives showed an increased excretion of fecal and urinary nitrogen. As a result, true nitrogen digestibility, BV, and net protein utilization were adversely affected. Protein digestibility corrected amino acid score was decreased for lysine, tryptophan, and sulfur containing amino acids.