Refine
Year of publication
Document Type
Is part of the Bibliography
- yes (61)
Keywords
- depression (6)
- Alcohol dependence (4)
- HIV (4)
- Reinforcement learning (4)
- dementia (4)
- Germany (3)
- alcohol (3)
- fMRI (3)
- quality of life (3)
- Decision-making (2)
- Dementia (2)
- Intelligence (2)
- Pavlovian-to-instrumental transfer (2)
- Physical activity (2)
- Psychotherapierichtlinie (2)
- Ventral striatum (2)
- addiction (2)
- agitation (2)
- alternative rewards (2)
- amygdala (2)
- animal and computational models (2)
- basic psychological need frustration (2)
- benzodiazepines (2)
- caregiver (2)
- cognitive-behavioral control (2)
- comorbidity (2)
- craving and relapse (2)
- exercise (2)
- exercise intensity (2)
- habit formation (2)
- high risk drinkers (2)
- ill-being (2)
- mental health (2)
- need satisfaction (2)
- nursing home (2)
- polygenic risk (2)
- risk factors (2)
- AAT (1)
- Affective modulation (1)
- Aging (1)
- Alcohol expectancy (1)
- Alzheimer dementia (1)
- Alzheimer disease (1)
- Alzheimers disease (1)
- Apathy (1)
- Avoidance learning (1)
- BPSD (1)
- Bimanual probe (1)
- Brain-derived neurotrophic factor (BDNF) (1)
- Caregiver (1)
- Computational psychiatry (1)
- D3 receptor (1)
- Depression (1)
- Depression symptoms (1)
- Depressive symptoms (1)
- Digital Health (1)
- Dimensional (1)
- Dopamine (1)
- Dopamine D2 (1)
- Dorsolateral prefrontal cortex (1)
- Drug prescription (1)
- Dyadic coping (1)
- Eastern-Western Germany (1)
- Electronic Health (1)
- Epigenetic Biomarkers (1)
- Error monitoring (1)
- Exclusion (1)
- First psychotic episode (1)
- Fist-Edge-Palm test (1)
- Goal-directed control (1)
- Human neuroimaging (1)
- Incidence rates (1)
- Intervention study (1)
- Luria (1)
- Major depressive disorder (1)
- Medial prefrontal cortex (1)
- Metabolic syndrome (1)
- Migration (1)
- Mobile Health (1)
- Mobile diagnostics (1)
- Monetary incentive delay task (1)
- Non-pharmacological intervention (1)
- Nucleus accumbens (1)
- Nutrition (1)
- Occupational therapy (1)
- Ostdeutschland (1)
- PET (1)
- POCD (1)
- Pavlovian-instrumental transfer (1)
- Perceived Stress Scale (1)
- Physical exercise (1)
- Physical training (1)
- Platelets (1)
- Polygenic Risk Score (1)
- Positron emission tomography (1)
- Prediction error (1)
- Prediction error signal (1)
- Prevention (1)
- Psychometric evaluation (1)
- Psychotropics (1)
- Quality-of-life (1)
- Relapse (1)
- Residential environment (1)
- Reversal learning (1)
- Reward Anticipation (1)
- Reward learning (1)
- Reward system (1)
- Richtlinienverfahren (1)
- Rural health (1)
- Schizophrenia (1)
- Schizophrenia spectrum disorders (1)
- Social capital (1)
- Social cohesion (1)
- Social functioning (1)
- Sport therapy (1)
- Stadt-Land-Vergleich (1)
- Stress (1)
- Stressful life events (1)
- Striatum (1)
- Suicide attempt (1)
- Telehealth (1)
- Telemedicine (1)
- Translation (1)
- Treatment outcome (1)
- Turkish migrants (1)
- Unterschiede (1)
- Westdeutschland (1)
- Workability (1)
- actor-partner interdependence model (1)
- aerobic exercise (1)
- alcohol addiction (1)
- animal-assisted therapy (1)
- antidepressants (1)
- association (1)
- autonomy support (1)
- basic psychological need satisfaction and frustration (1)
- cardiovascular (1)
- cardiovascular diseases (1)
- caregivers (1)
- clinical pathways (1)
- communication (1)
- comparison (1)
- cross-sectoral care (1)
- delirium prevention (1)
- depressive symptomatology (1)
- depressive symptoms (1)
- differences (1)
- dimensional (1)
- dog-assisted therapy (1)
- dopamine (1)
- drug (1)
- elderly people (1)
- goal-directed (1)
- guideline (1)
- health (1)
- life story book (1)
- long-term effects (1)
- long-term use (1)
- longitudinal cohort (1)
- meta-analysis (1)
- metaanalysis (1)
- metabolic disease (1)
- mild cognitive impairment (1)
- monetary incentive delay task (1)
- need support (1)
- older people (1)
- partner interdependence model (1)
- physical activity (1)
- physical exercise (1)
- postoperative cognitive dysfunction (1)
- prediction error (1)
- prescription patterns (1)
- primary care (1)
- psychometric properties (1)
- psychotherapy guideline (1)
- psychotherapy guidelines (1)
- psychotherapy methods (1)
- reinforcement learning (1)
- reminiscence (1)
- resistance training (1)
- reward system (1)
- risk screening (1)
- sedentary (1)
- technology (1)
- trial (1)
- urban-rural (1)
- ventral striatum (1)
Institute
- Department Sport- und Gesundheitswissenschaften (61) (remove)
When local poverty is more important than your income: Mental health in minorities in inner cities
(2015)
BACKGROUND: Addiction is supposedly characterized by a shift from goal-directed to habitual decision making, thus facilitating automatic drug intake. The two-step task allows distinguishing between these mechanisms by computationally modeling goal-directed and habitual behavior as model-based and model-free control. In addicted patients, decision making may also strongly depend upon drug-associated expectations. Therefore, we investigated model-based versus model-free decision making and its neural correlates as well as alcohol expectancies in alcohol-dependent patients and healthy controls and assessed treatment outcome in patients. METHODS: Ninety detoxified, medication-free, alcohol-dependent patients and 96 age-and gender-matched control subjects underwent functional magnetic resonance imaging during the two-step task. Alcohol expectancies were measured with the Alcohol Expectancy Questionnaire. Over a follow-up period of 48 weeks, 37 patients remained abstinent and 53 patients relapsed as indicated by the Alcohol Timeline Followback method. RESULTS: Patients who relapsed displayed reduced medial prefrontal cortex activation during model-based decision making. Furthermore, high alcohol expectancies were associated with low model-based control in relapsers, while the opposite was observed in abstainers and healthy control subjects. However, reduced model-based control per se was not associated with subsequent relapse. CONCLUSIONS: These findings suggest that poor treatment outcome in alcohol dependence does not simply result from a shift from model-based to model-free control but is instead dependent on the interaction between high drug expectancies and low model-based decision making. Reduced model-based medial prefrontal cortex signatures in those who relapse point to a neural correlate of relapse risk. These observations suggest that therapeutic interventions should target subjective alcohol expectancies.
Background
Depression is one of the key factors contributing to difficulties in one’s ability to work, and serves as one of the major reasons why employees apply for psychotherapy and receive insurance subsidization of treatments. Hence, an increasing and growing number of studies rely on workability assessment scales as their primary outcome measure. The Work and Social Assessment Scale (WSAS) has been documented as one of the most psychometrically reliable and valid tools especially developed to assess workability and social functioning in patients with mental health problems. Yet, the application of the WSAS in Germany has been limited due to the paucity of a valid questionnaire in the German language. The objective of the present study was to translate the WSAS, as a brief and easy administrable tool into German and test its psychometric properties in a sample of adults with depression.
Methods
Two hundred seventy-seven patients (M = 48.3 years, SD = 11.1) with mild to moderately severe depression were recruited. A multistep translation from English into the German language was performed and the factorial validity, criterion validity, convergent validity, discriminant validity, internal consistency, and floor and ceiling effects were examined.
Results
The confirmatory factor analysis results confirmed the one-factor structure of the WSAS. Significant correlations with the WHODAS 2–0 questionnaire, a measure of functionality, demonstrated good convergent validity. Significant correlations with depression and quality of life demonstrated good criterion validity. The WSAS also demonstrated strong internal consistency (α = .89), and the absence of floor and ceiling effects indicated good sensitivity of the instrument.
Conclusions
The results of the present study demonstrated that the German version of the WSAS has good psychometric properties comparable to other international versions of this scale. The findings recommend a global assessment of psychosocial functioning with the sum score of the WSAS.
Satisfaction and frustration of the needs for autonomy, competence, and relatedness, as assessed with the 24-item Basic Psychological Need Satisfaction and Frustration Scale (BPNSFS), have been found to be crucial indicators of individuals’ psychological health. To increase the usability of this scale within a clinical and health services research context, we aimed to validate a German short version (12 items) of this scale in individuals with depression including the examination of the relations from need frustration and need satisfaction to ill-being and quality of life (QOL). This cross-sectional study involved 344 adults diagnosed with depression (Mage (SD) = 47.5 years (11.1); 71.8% females). Confirmatory factor analyses indicated that the short version of the BPNSFS was not only reliable, but also fitted a six-factor structure (i.e., satisfaction/frustration X type of need). Subsequent structural equation modeling showed that need frustration related positively to indicators of ill-being and negatively to QOL. Surprisingly, need satisfaction did not predict differences in ill-being or QOL. The short form of the BPNSFS represents a practical instrument to measure need satisfaction and frustration in people with depression. Further, the results support recent evidence on the importance of especially need frustration in the prediction of psychopathology.
Satisfaction and frustration of the needs for autonomy, competence, and relatedness, as assessed with the 24-item Basic Psychological Need Satisfaction and Frustration Scale (BPNSFS), have been found to be crucial indicators of individuals’ psychological health. To increase the usability of this scale within a clinical and health services research context, we aimed to validate a German short version (12 items) of this scale in individuals with depression including the examination of the relations from need frustration and need satisfaction to ill-being and quality of life (QOL). This cross-sectional study involved 344 adults diagnosed with depression (Mage (SD) = 47.5 years (11.1); 71.8% females). Confirmatory factor analyses indicated that the short version of the BPNSFS was not only reliable, but also fitted a six-factor structure (i.e., satisfaction/frustration X type of need). Subsequent structural equation modeling showed that need frustration related positively to indicators of ill-being and negatively to QOL. Surprisingly, need satisfaction did not predict differences in ill-being or QOL. The short form of the BPNSFS represents a practical instrument to measure need satisfaction and frustration in people with depression. Further, the results support recent evidence on the importance of especially need frustration in the prediction of psychopathology.
Fluid intelligence (fluid IQ), defined as the capacity for rapid problem solving and behavioral adaptation, is known to be modulated by learning and experience. Both stressful life events (SLES) and neural correlates of learning [specifically, a key mediator of adaptive learning in the brain, namely the ventral striatal representation of prediction errors (PE)] have been shown to be associated with individual differences in fluid IQ. Here, we examine the interaction between adaptive learning signals (using a well-characterized probabilistic reversal learning task in combination with fMRI) and SLES on fluid IQ measures. We find that the correlation between ventral striatal BOLD PE and fluid IQ, which we have previously reported, is quantitatively modulated by the amount of reported SLES. Thus, after experiencing adversity, basic neuronal learning signatures appear to align more closely with a general measure of flexible learning (fluid IQ), a finding complementing studies on the effects of acute stress on learning. The results suggest that an understanding of the neurobiological correlates of trait variables like fluid IQ needs to take socioemotional influences such as chronic stress into account.
Purpose
To test whether the negative relationship between perceived stress and quality of life (Hypothesis 1) can be buffered by perceived social support in patients with dementia as well as in caregivers individually (Hypothesis 2: actor effects) and across partners (Hypothesis 3: partner effects and actor-partner effects).
Method
A total of 108 couples (N = 216 individuals) comprised of one individual with early-stage dementia and one caregiving partner were assessed at baseline and one month apart. Moderation effects were investigated by applying linear mixed models and actor-partner interdependence models.
Results
Although the stress-quality of life association was more pronounced in caregivers (beta = -.63, p<.001) compared to patients (beta= -.31, p<.001), this association was equally moderated by social support in patients (beta = .14, p<.05) and in the caregivers (beta =.13, p<.05). From one partner to his or her counterpart, the partner buffering and actor-partner-buffering effect were not present.
Conclusion
The stress-buffering effect has been replicated in individuals with dementia and caregivers but not across partners. Interventions to improve quality of life through perceived social support should not only focus on caregivers, but should incorporate both partners.
Purpose:
To test whether the negative relationship between perceived stress and quality of life (Hypothesis 1) can be buffered by perceived social support in patients with dementia as well as in caregivers individually (Hypothesis 2: actor effects) and across partners (Hypothesis 3: partner effects and actor-partner effects).
Method:
A total of 108 couples (N = 216 individuals) comprised of one individual with early-stage dementia and one caregiving partner were assessed at baseline and one month apart. Moderation effects were investigated by applying linear mixed models and actor-partner interdependence models.
Results:
Although the stress-quality of life association was more pronounced in caregivers (beta = -.63, p<.001) compared to patients (beta= -.31, p<.001), this association was equally moderated by social support in patients (beta = .14, p<.05) and in the caregivers (beta =.13, p<.05). From one partner to his or her counterpart, the partner buffering and actor-partner-buffering effect were not present.
Conclusion:
The stress-buffering effect has been replicated in individuals with dementia and caregivers but not across partners. Interventions to improve quality of life through perceived social support should not only focus on caregivers, but should incorporate both partners.