Refine
Has Fulltext
- no (3)
Document Type
- Article (3) (remove)
Language
- English (3) (remove)
Is part of the Bibliography
- yes (3)
Keywords
- Optimization (3) (remove)
Machine learning for improvement of thermal conditions inside a hybrid ventilated animal building
(2021)
In buildings with hybrid ventilation, natural ventilation opening positions (windows), mechanical ventilation rates, heating, and cooling are manipulated to maintain desired thermal conditions. The indoor temperature is regulated solely by ventilation (natural and mechanical) when the external conditions are favorable to save external heating and cooling energy. The ventilation parameters are determined by a rule-based control scheme, which is not optimal. This study proposes a methodology to enable real-time optimum control of ventilation parameters. We developed offline prediction models to estimate future thermal conditions from the data collected from building in operation. The developed offline model is then used to find the optimal controllable ventilation parameters in real-time to minimize the setpoint deviation in the building. With the proposed methodology, the experimental building's setpoint deviation improved for 87% of time, on average, by 0.53 degrees C compared to the current deviations.
Image-based styling
(2016)
The same data can be visualized using various visual styles that each is suitable for specific requirements, e.g., 3D geodata visualized using photorealistic, cartographic, or illustrative styles. In contrast to feature-based styling, image-based styling performed in image space at image resolution allows decoupling styling from image generation and output-sensitive, expressive styling. However, leveraging image-based styling is still impeded. No previous approach allows specifying image-based styling expressively with an extensive inventory of composable operators, while providing styling functionality in a service-oriented, interoperable manner. In this article, we present an interactive system for specifying and providing the functionality of image-based styling. As key characteristics, it separates concerns of styling from image generation and facilitates specifying styling as algebraic compositions of high-level operators using a unified 3D model representation. We propose a generalized visualization model, an image-based styling algebra, two declarative DSLs, an operator taxonomy, an operational model, and a standards-based service interface. The approach facilitates expressive specifications of image-based styling for design, description, and analysis and leveraging the functionality of image-based styling in a service-oriented, interoperable, reusable, and composable manner.
Background: Reconstruction of genome-scale metabolic networks has resulted in models capable of reproducing experimentally observed biomass yield/growth rates and predicting the effect of alterations in metabolism for biotechnological applications. The existing studies rely on modifying the metabolic network of an investigated organism by removing or inserting reactions taken either from evolutionary similar organisms or from databases of biochemical reactions (e.g., KEGG). A potential disadvantage of these knowledge-driven approaches is that the result is biased towards known reactions, as such approaches do not account for the possibility of including novel enzymes, together with the reactions they catalyze.
Results: Here, we explore the alternative of increasing biomass yield in three model organisms, namely Bacillus subtilis, Escherichia coil, and Hordeum vulgare, by applying small, chemically feasible network modifications. We use the predicted and experimentally confirmed growth rates of the wild-type networks as reference values and determine the effect of inserting mass-balanced, thermodynamically feasible reactions on predictions of growth rate by using flux balance analysis.
Conclusions: While many replacements of existing reactions naturally lead to a decrease or complete loss of biomass production ability, in all three investigated organisms we find feasible modifications which facilitate a significant increase in this biological function. We focus on modifications with feasible chemical properties and a significant increase in biomass yield. The results demonstrate that small modifications are sufficient to substantially alter biomass yield in the three organisms. The method can be used to predict the effect of targeted modifications on the yield of any set of metabolites (e.g., ethanol), thus providing a computational framework for synthetic metabolic engineering.