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Künstliche Intelligenz ist in aller Munde. Immer mehr Anwendungsbereiche werden durch die Auswertung von vorliegenden Daten mit Algorithmen und Frameworks z.B. des Maschinellen Lernens erschlossen. Dieses Buch hat das Ziel, einen Überblick über gegenwärtig vorhandene Lösungen zu geben und darüber hinaus konkrete Hilfestellung bei der Auswahl von Algorithmen oder Tools bei spezifischen Problemstellungen zu bieten. Um diesem Anspruch gerecht zu werden, wurden 90 Lösungen mittels einer systematischen Literaturrecherche und Praxissuche identifiziert sowie anschließend klassifiziert. Mit Hilfe dieses Buches gelingt es, schnell die notwendigen Grundlagen zu verstehen, gängige Anwendungsgebiete zu identifizieren und den Prozess zur Auswahl eines passenden ML-Tools für das eigene Projekt systematisch zu meistern.
This paper presents an exploratory study investigating the influence of the factors (1) intermediary participation, (2) decision-making authority, (3) position in the enterprise, and (4) experience in open innovation on the perception and assessment of the benefits and risks expected from participating in open innovation projects. For this purpose, an online survey was conducted in Germany, Austria and Switzerland. The result of this paper is an empirical evidence showing whether and how these factors affect the perception of potential benefits and risks expected within the context of open innovation project participation. Furthermore, the identified effects are discussed against the theory. Existing theory regarding the benefits and risks of open innovation is expanded by (1) finding that they are perceived mostly independently of the factors, (2) confirming the practical relevance of benefits and risks, and (3) enabling a finer distinction between their degrees of relevance according to respective contextual specifics.
Purpose The purpose of this paper is to shed light on the rising waves of workplace militancy in the public sector and to provide insights into the perceptions that frame justification for industrial action among Ugandan public sector employees. Design/methodology/approach In-depth interviews and documentary analysis, analysed qualitatively, as well as a review of theoretical and empirical literature. Findings Public school teachers and public university lecturers in Uganda who frequently engage in industrial action mainly rationalise their engagement by the absence, or the ineffectiveness of alternative conflict resolution mechanisms. The findings also show that industrial action, even in resource-constrained settings like Uganda, is stimulated more by the desire to achieve equity rather than by the basic desire to improve working conditions. It is also notable that new, often unstructured, forms of workplace militancy continue to emerge in the public sector, and waves of industrial action are shifting from the industrial to the public sector. Practical implications Whereas industrial action is a protected labour right, the findings of this research strongly suggest that public employees do not necessarily enjoy their right to engage, but only reluctantly take industrial action as a "last resort". The findings will, therefore, help public managers and policymakers to appreciate their responsibility in reducing the compulsion for industrial action among public employees. Originality/value This paper provides a general explanation for industrial action from the perspective of the people involved, rather than explaining the causality of specific strike actions. At a time when industrial action is generally declining in the developed industrialised states, this paper sheds light on the rise in collective action in developing countries and especially in the public sector.
Advanced non-viral gene delivery experiments often require co-delivery of multiple nucleic acids. Therefore, the availability of reliable and robust co-transfection methods and defined selection criteria for their use in, e.g., expression of multimeric proteins or mixed RNA/DNA delivery is of utmost importance. Here, we investigated different co- and successive transfection approaches, with particular focus on in vitro transcribed messenger RNA (IVT-mRNA). Expression levels and patterns of two fluorescent protein reporters were determined, using different IVT-mRNA doses, carriers, and cell types. Quantitative parameters determining the efficiency of co-delivery were analyzed for IVT-mRNAs premixed before nanocarrier formation (integrated co-transfection) and when simultaneously transfecting cells with separately formed nanocarriers (parallel co-transfection), which resulted in a much higher level of expression heterogeneity for the two reporters. Successive delivery of mRNA revealed a lower transfection efficiency in the second transfection round. All these differences proved to be more pronounced for low mRNA doses. Concurrent delivery of siRNA with mRNA also indicated the highest co-transfection efficiency for integrated method. However, the maximum efficacy was shown for successive delivery, due to the kinetically different peak output for the two discretely operating entities. Our findings provide guidance for selection of the co-delivery method best suited to accommodate experimental requirements, highlighting in particular the nucleic acid dose-response dependence on co-delivery on the single-cell level.
Issues The last Soviet anti-alcohol campaign of 1985 resulted in considerably reduced alcohol consumption and saved thousands of lives. But once the campaign's policies were abandoned and the Soviet alcohol monopoly broken up, a steep rise in mortality was observed in many of the newly formed successor countries, although some kept their monopolies. Almost 30 years after the campaign's end, the region faces diverse challenges in relation to alcohol.
Approach The present narrative review sheds light on recent drinking trends and alcohol policy developments in the 15 Former Soviet Union (FSU) countries, highlighting the most important setbacks, achievements and best practices. Vignettes of alcohol control policies in Belarus, Estonia, Kazakhstan, Lithuania and Uzbekistan are presented to illustrate the recent developments. <br /> Key Findings Over the past decade, drinking levels have declined in almost all FSU countries, paralleled by the introduction of various alcohol-control measures. The so-called three 'best buys' put forward by the World Health Organization to reduce alcohol-attributable burden (taxation and other measures to increase price, restrictions on alcohol availability and marketing) are relatively well implemented across the countries.
Implications In recent years, evidence-based alcohol policies have been actively implemented as a response to the enormous alcohol-attributable burden in many of the countries, although there is big variance across and within different jurisdictions.
Conclusion Strong declines in alcohol consumption were observed in the 15 FSU countries, which have introduced various alcohol control measures in recent years, resulting in a reduction of alcohol consumption in the World Health Organization European region overall.
Background: Voice-controlled intelligent personal assistants (VIPAs), such as Amazon Echo and Google Home, involve artificial intelligence-powered algorithms designed to simulate humans. Their hands-free interface and growing capabilities have a wide range of applications in health care, covering off-clinic education, health monitoring, and communication. However, conflicting factors, such as patient safety and privacy concerns, make it difficult to foresee the further development of VIPAs in health care. <br /> Objective: This study aimed to develop a plausible scenario for the further development of VIPAs in health care to support decision making regarding the procurement of VIPAs in health care organizations. Methods: We conducted a two-stage Delphi study with an internationally recruited panel consisting of voice assistant experts, medical professionals, and representatives of academia, governmental health authorities, and nonprofit health associations having expertise with voice technology. Twenty projections were formulated and evaluated by the panelists. Descriptive statistics were used to derive the desired scenario. <br /> Results: The panelists expect VIPAs to be able to provide solid medical advice based on patients' personal health information and to have human-like conversations. However, in the short term, voice assistants might neither provide frustration-free user experience nor outperform or replace humans in health care. With a high level of consensus, the experts agreed with the potential of VIPAs to support elderly people and be widely used as anamnesis, informational, self-therapy, and communication tools by patients and health care professionals. Although users' and governments' privacy concerns are not expected to decrease in the near future, the panelists believe that strict regulations capable of preventing VIPAs from providing medical help services will not be imposed. <br /> Conclusions: According to the surveyed experts, VIPAs will show notable technological development and gain more user trust in the near future, resulting in widespread application in health care. However, voice assistants are expected to solely support health care professionals in their daily operations and will not be able to outperform or replace medical staff.
Cyber-physical systems (CPS) have shaped the discussion about Industry 4.0 (I4.0) for some time. To ensure the competitiveness of manufacturing enterprises the vision for the future figures out cyber-physical production systems (CPPS) as a core component of a modern factory. Adaptability and coping with complexity are (among others) potentials of this new generation of production management. The successful transformation of this theoretical construct into practical implementation can only take place with regard to the conditions characterizing the context of a factory. The subject of this contribution is a concept that takes up the brownfield character and describes a solution for extending existing (legacy) systems with CPS capabilities.
Introduction
(2020)
Does political repression work and if so, under what conditions? Many contributions to the empirical study of non-democratic rule assume it does. As a consequence, strong convictions on political repression abound, but empirical investigations into the matter remain rare. This introduction sets the agenda for the chapters to come and outlines the answers given to the three motivating questions of this volume. First, what variants of political repression are there, and how do they interact? Second, what impact does the interaction of different forms of political repression have on the problem of authoritarian control? Finally, what difference does the complementary use of violence and restrictions make for the problem of authoritarian power-sharing?
This article contributes to the debate on the incorporation of performance information in European local government budgets. At the core is the development of an analytical model for comparing efforts of performance budgeting (PB). Evidence in ten cases indicates that performance structures and the span of performance differ, that performance indicators are far from always measuring outcomes or outputs, and that future and past performance figures are often absent. Nevertheless similar learning trajectories do exist. Possible explanations for the variation involve the varying degrees of reform implementation, experience with PB and prevailing institutional arrangements.