Refine
Year of publication
- 2021 (4) (remove)
Document Type
- Article (2)
- Part of Periodical (1)
- Postprint (1)
Language
- English (4)
Is part of the Bibliography
- yes (4)
Keywords
- Duchenne muscular dystrophy (2)
- child development (2)
- embodied cognition (2)
- mathematics (2)
- neuromuscular disease (2)
- numerical processing (2)
- spatial-numerical associations (2)
- spinal muscular atrophy (2)
- 19. Jahrhundert (1)
- 19th century (1)
Spinal muscular atrophy (SMA) and Duchenne muscular dystrophy (DMD) both are rare genetic neuromuscular diseases with progressive loss of motor ability. The neuromotor developmental course of those diseases is well documented. In contrast, there is only little evidence about characteristics of general and specific cognitive development. In both conditions the final motor outcome is characterized by an inability to move autonomously: children with SMA never accomplish independent motoric exploration of their environment, while children with DMD do but later lose this ability again. These profound differences in developmental pathways might affect cognitive development of SMA vs. DMD children, as cognition is shaped by individual motor experiences. DMD patients show impaired executive functions, working memory, and verbal IQ, whereas only motor ability seems to be impaired in SMA. Advanced cognitive capacity in SMA may serve as a compensatory mechanism for achieving in education, career progression, and social satisfaction. This study aimed to relate differences in basic numerical concepts and arithmetic achievement in SMA and DMD patients to differences in their motor development and resulting sensorimotor and environmental experiences. Horizontal and vertical spatial-numerical associations were explored in SMA/DMD children ranging between 6 and 12 years through the random number generation task. Furthermore, arithmetic skills as well as general cognitive ability were assessed. Groups differed in spatial number processing as well as in arithmetic and domain-general cognitive functions. Children with SMA showed no horizontal and even reversed vertical spatial-numerical associations. Children with DMD on the other hand revealed patterns in spatial numerical associations comparable to healthy developing children. From the embodied Cognition perspective, early sensorimotor experience does play a role in development of mental number representations. However, it remains open whether and how this becomes relevant for the acquisition of higher order cognitive and arithmetic skills.
The precise and accurate assessment of carbon dioxide (CO2) exchange is crucial to identify terrestrial carbon (C) sources and sinks and for evaluating their role within the global C budget. The substantial uncertainty in disentangling the management and soil impact on measured CO2 fluxes are largely ignored especially in cropland. The reasons for this lies in the limitation of the widely used eddy covariance as well as manual and automatic chamber systems, which either account for short-term temporal variability or small-scale spatial heterogeneity, but barely both. To address this issue, we developed a novel robotic chamber system allowing for dozens of spatial measurement repetitions, thus enabling CO2 exchange measurements in a sufficient temporal and high small-scale spatial resolution. The system was tested from 08th July to 09th September 2019 at a heterogeneous field (100 m x 16 m), located within the hummocky ground moraine landscape of northeastern Germany (CarboZALF-D). The field is foreseen for a longer-term block trial manipulation experiment extending over three erosion induced soil types and was covered with spring barley. Measured fluxes of nighttime ecosystem respiration (R-eco) and daytime net ecosystem exchange (NEE) showed distinct temporal patterns influenced by crop phenology, weather conditions and management practices. Similarly, we found clear small-scale spatial differences in cumulated (gap-filled) R-eco, gross primary productivity (GPP) and NEE fluxes affected by the three distinct soil types. Additionally, spatial patterns induced by former management practices and characterized by differences in soil pH and nutrition status (P and K) were also revealed between plots within each of the three soil types, which allowed compensating for prior to the foreseen block trial manipulation experiment. The results underline the great potential of the novel robotic chamber system, which not only detects short-term temporal CO2 flux dynamics but also reflects the impact of small-scale spatial heterogeneity.
Spinal muscular atrophy (SMA) and Duchenne muscular dystrophy (DMD) both are rare genetic neuromuscular diseases with progressive loss of motor ability. The neuromotor developmental course of those diseases is well documented. In contrast, there is only little evidence about characteristics of general and specific cognitive development. In both conditions the final motor outcome is characterized by an inability to move autonomously: children with SMA never accomplish independent motoric exploration of their environment, while children with DMD do but later lose this ability again. These profound differences in developmental pathways might affect cognitive development of SMA vs. DMD children, as cognition is shaped by individual motor experiences. DMD patients show impaired executive functions, working memory, and verbal IQ, whereas only motor ability seems to be impaired in SMA. Advanced cognitive capacity in SMA may serve as a compensatory mechanism for achieving in education, career progression, and social satisfaction. This study aimed to relate differences in basic numerical concepts and arithmetic achievement in SMA and DMD patients to differences in their motor development and resulting sensorimotor and environmental experiences. Horizontal and vertical spatial-numerical associations were explored in SMA/DMD children ranging between 6 and 12 years through the random number generation task. Furthermore, arithmetic skills as well as general cognitive ability were assessed. Groups differed in spatial number processing as well as in arithmetic and domain-general cognitive functions. Children with SMA showed no horizontal and even reversed vertical spatial-numerical associations. Children with DMD on the other hand revealed patterns in spatial numerical associations comparable to healthy developing children. From the embodied Cognition perspective, early sensorimotor experience does play a role in development of mental number representations. However, it remains open whether and how this becomes relevant for the acquisition of higher order cognitive and arithmetic skills.
The field of American Jewish studies has recently trained its focus on the transnational dimensions of its subject, reflecting in more sustained ways than before about the theories and methods of this approach. Yet, much of the insight to be gained from seeing American Jewry as constitutively entangled in many ways with other Jewries has not yet been realized. Transnational American Jewish studies are still in their infancy.
This issue of PaRDeS presents current research on the multiple entanglements of American with Central European, especially German-speaking Jewries in the 19th and 20th centuries. The articles reflect the wide range of topics that can benefit from a transnational understanding of the American Jewish experience as shaped by its foreign entanglements.