Refine
Has Fulltext
- no (36)
Language
- English (36)
Is part of the Bibliography
- yes (36)
Keywords
- radiation mechanisms: non-thermal (11)
- galaxies: active (8)
- gamma rays: galaxies (8)
- gamma rays: general (8)
- ISM: supernova remnants (6)
- ISM: clouds (3)
- acceleration of particles (3)
- cosmic rays (3)
- galaxies: jets (3)
- BL Lacertae objects: individual: PKS 2155-304 (2)
- ISM: individual objects: G338.3-0.0 (2)
- errata, addenda (2)
- gamma rays: ISM (2)
- gamma-rays: galaxies (2)
- Air showers (1)
- BL Lacertae objects: general (1)
- BL Lacertae objects: individual (PG 1553+113) (1)
- BL Lacertae objects: individual: 1ES 1312-423 (1)
- BL Lacertae objects: individual: AP Librae (1)
- BL Lacertae objects: individual: PKS 0301-243 (1)
- BL Lacertae objects: individual: PKS 0447-439 (1)
- BL Lacertae objects: individual: SHBL J001355.9-185406 (1)
- BL Lacertae objects: individual: lES 0229+200 (1)
- BL Lacertae objects: individual: lES 1101-232 (1)
- Cherenkov Telescopes (1)
- ISM: individual objects (SNR G338.3-0.0, SNR G338.5+0.1) (1)
- ISM: individual objects: Crab nebula (1)
- ISM: individual objects: HESS J1832-093 (1)
- ISM: individual objects: Puppis A (1)
- ISM: individual objects: SNR G1.9+0.3 (1)
- ISM: individual objects: SNR G22.7-0.2 (1)
- ISM: individual objects: SNR G330.2+1.0 (1)
- ISM: magnetic fields (1)
- TeV gamma-ray astronomy (1)
- X-rays: binaries (1)
- X-rays: general (1)
- X-rays: individuals: G15.4+0.1 (1)
- X-rays: stars (1)
- astroparticle physics (1)
- binaries: general (1)
- black hole physics (1)
- galaxies: distances and redshifts (1)
- galaxies: individual (M 87) (1)
- galaxies: magnetic fields (1)
- galaxies: nuclei (1)
- gamma rays: general(HESS J0632+057, VER J0633+057) (1)
- gamma rays: stars (1)
- gamma-ray burst: individual: GRB 100621A (1)
- gamma-rays: ISM (1)
- gamma-rays: general (1)
- globular clusters: general (1)
- infrared: diffuse background (1)
- intergalactic medium (1)
- methods: observational (1)
- pulsars: general (1)
- pulsars: individual: PSR B1259-63 (1)
- quasars: individual: PKS 1510-089 (1)
- relativistic processes (1)
- stars: individual: LS 2883 (1)
- supernovae: individual: HESS J1818-154 (1)
Discovery of high and very high-energy emission from the BL Lacertae object SHBL J001355.9-185406
(2013)
The detection of the high-frequency peaked BL Lac object (HBL) SHBL J001355.9-185406 (z = 0.095) at high (HE; 100 MeV < E < 300 GeV) and very high-energy (VHE; E > 100 GeV) with the Fermi Large Area Telescope (LAT) and the High Energy Stereoscopic System (H.E.S.S.) is reported. Dedicated observations were performed with the H. E. S. S. telescopes, leading to a detection at the 5.5 sigma significance level. The measured flux above 310 GeV is (8.3 +/- 1.7(stat) +/- 1.7(sys)) x 10(-13) photons cm(-2) s(-1) (about 0.6% of that of the Crab Nebula), and the power-law spectrum has a photon index of Gamma = 3.4 +/- 0.5(stat) +/- 0.2(sys). Using 3.5 years of publicly available Fermi-LAT data, a faint counterpart has been detected in the LAT data at the 5.5 sigma significance level, with an integrated flux above 300 MeV of (9.3 +/- 3.4(stat) +/- 0.8(sys)) x 10(-10) photons cm(-2) s(-1) and a photon index of Gamma = 1.96 +/- 0.20(stat) +/- 0.08(sys). X-ray observations with Swift-XRT allow the synchrotron peak energy in vF(v) representation to be located at similar to 1.0 keV. The broadband spectral energy distribution is modelled with a one-zone synchrotron self-Compton (SSC) model and the optical data by a black-body emission describing the thermal emission of the host galaxy. The derived parameters are typical of HBLs detected at VHE, with a particle-dominated jet.
Diffuse gamma-ray emission is the most prominent observable signature of celestial cosmic-ray interactions at high energies. While already being investigated at GeVenergies over several decades, assessments of diffuse gamma-ray emission at TeVenergies remain sparse. After completion of the systematic survey of the inner Galaxy, the H.E.S.S. experiment is in a prime position to observe large-scale diffuse emission at TeVenergies. Data of the H.E.S.S. Galactic Plane Survey are investigated in regions off known gamma-ray sources. Corresponding gamma-ray flux measurements were made over an extensive grid of celestial locations. Longitudinal and latitudinal profiles of the observed gamma-ray fluxes show characteristic excess emission not attributable to known gamma-ray sources. For the first time large-scale gamma-ray emission along the Galactic plane using imaging atmospheric Cherenkov telescopes has been observed. While the background subtraction technique limits the ability to recover modest variation on the scale of the H.E.S.S. field of view or larger, which is characteristic of the inverse Compton scatter-induced Galactic diffuse emission, contributions of neutral pion decay as well as emission from unresolved gamma-ray sources can be recovered in the observed signal to a large fraction. Calculations show that the minimum gamma-ray emission from pi(0) decay represents a significant contribution to the total signal. This detection is interpreted as a mix of diffuse Galactic gamma-ray emission and unresolved sources.
Axionlike particles (ALPs) are hypothetical light (sub-eV) bosons predicted in some extensions of the Standard Model of particle physics. In astrophysical environments comprising high-energy gamma rays and turbulent magnetic fields, the existence of ALPs can modify the energy spectrum of the gamma rays for a sufficiently large coupling between ALPs and photons. This modification would take the form of an irregular behavior of the energy spectrum in a limited energy range. Data from the H. E. S. S. observations of the distant BL Lac object PKS 2155 - 304 (z = 0.116) are used to derive upper limits at the 95% C. L. on the strength of the ALP coupling to photons, g(gamma a) < 2.1 x 10(-11) GeV-1 for an ALP mass between 15 and 60 neV. The results depend on assumptions on the magnetic field around the source, which are chosen conservatively. The derived constraints apply to both light pseudoscalar and scalar bosons that couple to the electromagnetic field.
An annihilation signal of dark matter is searched for from the central region of the Milky Way. Data acquired in dedicated on-off observations of the Galactic center region with H.E.S.S. are analyzed for this purpose. No significant signal is found in a total of similar to 9 h of on-off observations. Upper limits on the velocity averaged cross section, <sigma upsilon >, for the annihilation of dark matter particles with masses in the range of similar to 300 GeV to similar to 10 TeV are derived. In contrast to previous constraints derived from observations of the Galactic center region, the constraints that are derived here apply also under the assumption of a central core of constant dark matter density around the center of the Galaxy. Values of <sigma upsilon > that are larger than 3 x 10(-24) cm(3)/s are excluded for dark matter particles with masses between similar to 1 and similar to 4 TeV at 95% C.L. if the radius of the central dark matter density core does not exceed 500 pc. This is the strongest constraint that is derived on <sigma upsilon > for annihilating TeV mass dark matter without the assumption of a centrally cusped dark matter density distribution in the search region.
To identify genetic variants associated with head circumference in infancy, we performed a meta-analysis of seven genome-wide association studies (GWAS) (N = 10,768 individuals of European ancestry enrolled in pregnancy and/or birth cohorts) and followed up three lead signals in six replication studies (combined N = 19,089). rs7980687 on chromosome 12q24 (P = 8.1 x 10(-9)) and rs1042725 on chromosome 12q15 (P = 2.8 x 10(-10)) were robustly associated with head circumference in infancy. Although these loci have previously been associated with adult height(1), their effects on infant head circumference were largely independent of height (P = 3.8 x 10(-7) for rs7980687 and P = 1.3 x 10(-7) for rs1042725 after adjustment for infant height). A third signal, rs11655470 on chromosome 17q21, showed suggestive evidence of association with head circumference (P = 3.9 x 10(-6)). SNPs correlated to the 17q21 signal have shown genome-wide association with adult intracranial volume(2), Parkinson's disease and other neurodegenerative diseases(3-5), indicating that a common genetic variant in this region might link early brain growth with neurological disease in later life.
A catalog of genetic loci associated with kidney function from analyses of a million individuals
(2019)
Chronic kidney disease (CKD) is responsible for a public health burden with multi-systemic complications. Through transancestry meta-analysis of genome-wide association studies of estimated glomerular filtration rate (eGFR) and independent replication (n = 1,046,070), we identified 264 associated loci (166 new). Of these,147 were likely to be relevant for kidney function on the basis of associations with the alternative kidney function marker blood urea nitrogen (n = 416,178). Pathway and enrichment analyses, including mouse models with renal phenotypes, support the kidney as the main target organ. A genetic risk score for lower eGFR was associated with clinically diagnosed CKD in 452,264 independent individuals. Colocalization analyses of associations with eGFR among 783,978 European-ancestry individuals and gene expression across 46 human tissues, including tubulo-interstitial and glomerular kidney compartments, identified 17 genes differentially expressed in kidney. Fine-mapping highlighted missense driver variants in 11 genes and kidney-specific regulatory variants. These results provide a comprehensive priority list of molecular targets for translational research.