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- Institut für Mathematik (53)
- Historisches Institut (50)
Dieser Band der Schriftenreihe der Badischen Heimat will im Rahmen der Vielzahl von Publikationen, die in diesem Jahr an den Beginn des Ersten Weltkrieges erinnern, einen besonderen Beitrag leisten. Gleichsam als „Geschichte von unten“ wirkend, gibt die vorliegende Sammlung der Feldpostbriefe einen gefilterten Eindruck in das Seelenleben der Kriegsgeneration wieder. Sie ist als Kollektion badischer Soldatenbriefe in dieser Form bisher einmalig und erweitert das Wahrnehmungsspektrum der scheinbar in weiter Ferne und dennoch so nah liegenden „Urkatastrophe“ um eine weitere wichtige Nuance.
Gamba, Cristina ; Jones, Eppie R. ; Teasdale, Matthew D. ; McLaughlin, Russell L. ; González-Fortes, Gloria M. ; Mattiangeli, Valeria ; Domboróczki, László ; Kővári, Ivett ; Pap, Ildikó ; Anders, Alexandra ; Whittle, Alasdair ; Dani, János ; Raczky, Pál ; Higham, Thomas F. G. ; Hofreiter, Michael ; Bradley, Daniel G. ; Pinhasi, Ron
The Great Hungarian Plain was a crossroads of cultural transformations that have shaped European prehistory. Here we analyse a 5,000-year transect of human genomes, sampled from petrous bones giving consistently excellent endogenous DNA yields, from 13 Hungarian Neolithic, Copper, Bronze and Iron Age burials including two to high (similar to 22x) and seven to similar to 1x coverage, to investigate the impact of these on Europe's genetic landscape. These data suggest genomic shifts with the advent of the Neolithic, Bronze and Iron Ages, with interleaved periods of genome stability. The earliest Neolithic context genome shows a European hunter-gatherer genetic signature and a restricted ancestral population size, suggesting direct contact between cultures after the arrival of the first farmers into Europe. The latest, Iron Age, sample reveals an eastern genomic influence concordant with introduced Steppe burial rites. We observe transition towards lighter pigmentation and surprisingly, no Neolithic presence of lactase persistence.
Pajoro, Alice ; Madrigal, Pedro ; Muiño, Jose M. ; Matus, José Tomás ; Jin, Jian ; Mecchia, Martin A. ; Debernardi, Juan M. ; Palatnik, Javier F. ; Balazadeh, Salma ; Arif, Muhammad ; Ó’Maoiléidigh, Diarmuid S. ; Wellmer, Frank ; Krajewski, Pawel ; Riechmann, José-Luis ; Angenent, Gerco C. ; Kaufmann, Kerstin
Background: Development of eukaryotic organisms is controlled by transcription factors that trigger specific and global changes in gene expression programs. In plants, MADS-domain transcription factors act as master regulators of developmental switches and organ specification. However, the mechanisms by which these factors dynamically regulate the expression of their target genes at different developmental stages are still poorly understood.
Results: We characterized the relationship of chromatin accessibility, gene expression, and DNA binding of two MADS-domain proteins at different stages of Arabidopsis flower development. Dynamic changes in APETALA1 and SEPALLATA3 DNA binding correlated with changes in gene expression, and many of the target genes could be associated with the developmental stage in which they are transcriptionally controlled. We also observe dynamic changes in chromatin accessibility during flower development. Remarkably, DNA binding of APETALA1 and SEPALLATA3 is largely independent of the accessibility status of their binding regions and it can precede increases in DNA accessibility. These results suggest that APETALA1 and SEPALLATA3 may modulate chromatin accessibility, thereby facilitating access of other transcriptional regulators to their target genes.
Conclusions: Our findings indicate that different homeotic factors regulate partly overlapping, yet also distinctive sets of target genes in a partly stage-specific fashion. By combining the information from DNA-binding and gene expression data, we are able to propose models of stage-specific regulatory interactions, thereby addressing dynamics of regulatory networks throughout flower development. Furthermore, MADS-domain TFs may regulate gene expression by alternative strategies, one of which is modulation of chromatin accessibility.
Individualistische Ansätze können die sozialen Dynamiken terroristischen Handelns nur unzureichend erklären, da sie keine Terrorismusanalysen, sondern Analysen von Terroristen liefern. Der Aufsatz geht deshalb von Georg Simmels formaler Analyse der „Geheimen Gesellschaft“ aus und entwickelt auf dieser Grundlage eine soziologische Erklärung dafür, wie die sozialen Beziehungen innerhalb solcher Gruppierungen die Opportunitätsstrukturen ihrer Mitglieder so strukturieren, dass ein Handeln entsteht, das wir als terroristisch bezeichnen können.
Von Ulfila bis Rekkared
(2014)
Für etwa 200 Jahre, vom Ende des 4. Jahrhunderts bis 589 n. Chr., gehören die Westgoten einem von der Orthodoxie der Reichskirche abweichenden christlichen Bekenntnis an. Auf dem 3. Konzil von Toledo beendet König Rekkared diesen Zustand religiöser Alterität durch die Konversion zum Katholizismus. Die antiken Berichte zeichnen nur vordergründig ein kohärentes Bild des Christentums der Goten. Dagegen weist Eike Faber Widersprüche und Fehler in der Überlieferung nach und bietet eine Reihe neuer Interpretationen an. Die genauere Betrachtung vermag dabei sowohl den dogmatischen Gehalt des Christentums der Goten schärfer zu konturieren als auch die Beweggründe für die Annahme des neuen Glaubens herauszustellen und die traditionelle Datierung dieses Vorgangs zu widerlegen. Schließlich wird deutlich, welche Funktion das fortgesetzte Festhalten an einer demonstrativ anderen religiösen Überzeugung für die Goten hatte. Prägnante Wegmarken der gotischen Geschichte, wie die Bibelübersetzung Ulfilas, die Eroberung und Plünderung Roms 410 n. Chr. oder die demonstrative Aufgabe der religiösen Differenz durch König Rekkared, werden erst durch diesen neuen, umfassenden Kontext verständlich.
Experiment Unterricht
(2014)