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The main objective of this study was to identify genomic regions involved in biomass heterosis using QTL, generation means, and mode-of-inheritance classification analyses. In a modified North Carolina Design III we backcrossed 429 recombinant inbred line and 140 introgression line populations to the two parental accessions, C24 and Col-0, whose F 1 hybrid exhibited 44% heterosis for biomass. Mid-parent heterosis in the RILs ranged from −31 to 99% for dry weight and from −58 to 143% for leaf area. We detected ten genomic positions involved in biomass heterosis at an early developmental stage, individually explaining between 2.4 and 15.7% of the phenotypic variation. While overdominant gene action was prevalent in heterotic QTL, our results suggest that a combination of dominance, overdominance and epistasis is involved in biomass heterosis in this Arabidopsis cross.
Prediction of hybrid biomass in Arabidopsis thaliana by selected parental SNP and metabolic markers
(2009)
A recombinant inbred line (RIL) population, derived from two Arabidopsis thaliana accessions, and the corresponding testcrosses with these two original accessions were used for the development and validation of machine learning models to predict the biomass of hybrids. Genetic and metabolic information of the RILs served as predictors. Feature selection reduced the number of variables (genetic and metabolic markers) in the models by more than 80% without impairing the predictive power. Thus, potential biomarkers have been revealed. Metabolites were shown to bear information on inherited macroscopic phenotypes. This proof of concept could be interesting for breeders. The example population exhibits substantial mid-parent biomass heterosis. The results of feature selection could therefore be used to shed light on the origin of heterosis. In this respect, mainly dominance effects were detected.
ie athenische Totenrede (epitaphios logos) spielte eine Schlüsselrolle bei der Konstruktion des idealisierten Selbstbildes des demokratischen Athen (5./4. Jh.v.Chr.). Dieser Aufsatz zeigt auf, dass die beiden bekanntesten Beispiele für das rhetorische Genre, die Rede des Perikes auf die Gefallenen bei Thukydides und die Rede des Sokrates im platonischen Dialog Menexenos, tatsächlich scharfe Kritik an der Instituton der Totenrede und an der demokratischen Polis an sich üben, obwohl beide Texte für sich betrachtet gemeinhin als affirmativ verstanden werden.
Lebenswissen nach Cavell
(2009)
Wiederholte Wiederholung
(2009)
In Quest of Subjectivity
(2009)
Personalauswahl
(2009)