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Stereoselective syntheses of enantiomerically pure 2,5-disubstituted dihydropyrans based on olefin metathesis

  • A short synthesis of 2,5-disubstituted dihydropyrans starting from D-mannitol as a chiral building block is described. Our synthetic approach combines ruthenium-catalyzed ring closing olefin metathesis and palladium-catalyzed nucleophilic substitution.

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Author details:Bernd SchmidtORCiDGND, Stefan Nave
DOI:https://doi.org/10.1021/jo061190k
ISSN:0022-3263
Pubmed ID:https://pubmed.ncbi.nlm.nih.gov/16958531
Title of parent work (English):The journal of organic chemistry
Publisher:American Chemical Society
Place of publishing:Washington
Publication type:Article
Language:English
Date of first publication:2006/08/19
Publication year:2006
Release date:2020/05/26
Volume:71
Issue:19
Number of pages:6
First page:7364
Last Page:7369
Organizational units:Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie
DDC classification:5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften
Peer review:Referiert
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