Thermo-Induced Aggregation and Crystallization of Block Copolypeptoids in Water
- Block copolypeptoids comprising a thermosensitive, crystallizable poly(N-(n-propyl)glycine) block and a watersoluble poly(N-methylglycine) block, P70My (y = 23, 42, 76, 153, and 290), were synthesized bY ring-opening polymerization of the corresponding N-alkylglycine N-carboxyanhydrides (NCAs) and examined according to their thermo-induced aggregation and crystallization in water by turbidimetty, micro-differential scanning calorimetry (micro-DSC); cryogenic scanning electron microscopy (cryo-SEM), analytical ultracentrifugation (AUC), and static light scattering (SLS). At a temperature above the cloud point temperature, the initially formed micellar aggregates started to crystallize and grow into larger complex assemblies of about 100-500 nm, exhibiting flower-like (P70M23), ellipsoidal (P70M42 and P70M72) or irregular shapes (P70M153 and.P70M290).
| Author details: | Christian Secker, Antje Voelkel, Brigitte TierschORCiD, Joachim KoetzORCiDGND, Helmut SchlaadORCiDGND |
|---|---|
| DOI: | https://doi.org/10.1021/acs.macromol.5b02481 |
| ISSN: | 0024-9297 |
| ISSN: | 1520-5835 |
| Title of parent work (English): | Macromolecules : a publication of the American Chemical Society |
| Publisher: | American Chemical Society |
| Place of publishing: | Washington |
| Publication type: | Article |
| Language: | English |
| Year of first publication: | 2016 |
| Publication year: | 2016 |
| Release date: | 2020/03/22 |
| Volume: | 49 |
| Number of pages: | 7 |
| First page: | 979 |
| Last Page: | 985 |
| Funding institution: | Max Planck Society; University of Potsdam |
| Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie |
| Peer review: | Referiert |
