Thermo-Induced Aggregation and Crystallization of Block Copolypeptoids in Water
- Block copolypeptoids comprising a thermosensitive, crystallizable poly(N-(n-propyl)glycine) block and a watersoluble poly(N-methylglycine) block, P70My (y = 23, 42, 76, 153, and 290), were synthesized bY ring-opening polymerization of the corresponding N-alkylglycine N-carboxyanhydrides (NCAs) and examined according to their thermo-induced aggregation and crystallization in water by turbidimetty, micro-differential scanning calorimetry (micro-DSC); cryogenic scanning electron microscopy (cryo-SEM), analytical ultracentrifugation (AUC), and static light scattering (SLS). At a temperature above the cloud point temperature, the initially formed micellar aggregates started to crystallize and grow into larger complex assemblies of about 100-500 nm, exhibiting flower-like (P70M23), ellipsoidal (P70M42 and P70M72) or irregular shapes (P70M153 and.P70M290).
Author details: | Christian Secker, Antje Voelkel, Brigitte TierschORCiD, Joachim KoetzORCiDGND, Helmut SchlaadORCiDGND |
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DOI: | https://doi.org/10.1021/acs.macromol.5b02481 |
ISSN: | 0024-9297 |
ISSN: | 1520-5835 |
Title of parent work (English): | Macromolecules : a publication of the American Chemical Society |
Publisher: | American Chemical Society |
Place of publishing: | Washington |
Publication type: | Article |
Language: | English |
Year of first publication: | 2016 |
Publication year: | 2016 |
Release date: | 2020/03/22 |
Volume: | 49 |
Number of pages: | 7 |
First page: | 979 |
Last Page: | 985 |
Funding institution: | Max Planck Society; University of Potsdam |
Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie |
Peer review: | Referiert |