Janus emulsion mediated porous scaffold bio-fabrication
- A three dimensional biopolymer network structure with incorporated nano-porous calcium phosphate (CaP) balls was fabricated by using gelatin-chitosan (GC) polymer blend and GC stabilized olive/silicone oil Janus emulsions, respectively. The emulsions were freeze-dried, and the oil droplets were washed out in order to prepare porous scaffolds with larger surface area. The morphology, pore size, chemical composition, thermal and swelling behavior was studied by Scanning Electron Microscopy (SEM), Fourier Transform Infrared Spectroscopy (FTIR) and micro-Differential Scanning Calorimetry (micro-DSC). Microscopic analysis confirmed that the pore size of the GC based sponges after freeze-drying may be drastically reduced by using Janus emulsions. Besides, the incorporation of nanoporous calcium phosphate balls is also lowering the pore size and enhancing thermal stability. (C) 2016 Elsevier B.V. All rights reserved.
| Author details: | Ildiko Kovach, Jens Rumschöttel, Stig E. Friberg, Joachim KoetzORCiDGND |
|---|---|
| DOI: | https://doi.org/10.1016/j.colsurfb.2016.05.018 |
| ISSN: | 0927-7765 |
| ISSN: | 1873-4367 |
| Pubmed ID: | https://pubmed.ncbi.nlm.nih.gov/27214784 |
| Title of parent work (English): | Colloids and surfaces : an international journal devoted to fundamental and applied research on colloid and interfacial phenomena in relation to systems of biological origin ; B, Biointerfaces |
| Publisher: | Elsevier |
| Place of publishing: | Amsterdam |
| Publication type: | Article |
| Language: | English |
| Year of first publication: | 2016 |
| Publication year: | 2016 |
| Release date: | 2020/03/22 |
| Tag: | Calcium phosphates; Gelatin-chitosan scaffolds; Janus emulsions |
| Volume: | 145 |
| Number of pages: | 6 |
| First page: | 347 |
| Last Page: | 352 |
| Funding institution: | Ugelstad Laboratory |
| Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie |
| Peer review: | Referiert |
