Synthesis of chromanes through RCM-Transfer hydrogenation
- A sequential ruthenium-catalyzed ring-closing metathesis-transfer hydrogenation sequence has been established as a synthesis of chromanes starting from 2-(allyloxy)styrenes. The sequence requires only one precatalyst, the first-generation Grubbs catalyst, which is converted into a ruthenium hydride species in situ. Propan-2-ol serves as a chemical trigger for the formation of the ruthenium hydride and as hydrogen source.
Author details: | Bernd SchmidtORCiDGND, Stefan Krehl, Veronica Sotelo-Meza |
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DOI: | https://doi.org/10.1055/s-0031-1289758 |
ISSN: | 0039-7881 |
Title of parent work (English): | Synthesis |
Publisher: | Thieme |
Place of publishing: | Stuttgart |
Publication type: | Article |
Language: | English |
Year of first publication: | 2012 |
Publication year: | 2012 |
Release date: | 2017/03/26 |
Tag: | chromanes; metathesis; ruthenium; styrenes; tandem reactions |
Volume: | 44 |
Issue: | 11 |
Number of pages: | 11 |
First page: | 1603 |
Last Page: | 1613 |
Funding institution: | Deutsche Forschungsgemeinschaft (DFG) [Schm 1095/6] |
Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie |
Peer review: | Referiert |