Electrospinning of Crystallizable Polypeptoid Fibers
- A unique fabrication process of low molar mass, crystalline polypeptoid fibers is described. Thermoresponsive fiber mats are prepared by electrospinning a homogeneous blend of semicrystalline poly(N-(n-propyl) glycine) (PPGly; 4.1 kDa) with high molar mass poly(ethylene oxide) (PEO). Annealing of these fibers at approximate to 100 degrees C selectively removes the PEO and produces stable crystalline fiber mats of pure PPGly, which are insoluble in aqueous solution but can be redissolved in methanol or ethanol. The formation of water-stable polypeptoid fiber mats is an important step toward their utilization in biomedical applications such as tissue engineering or wound dressing.
| Author details: | Michael W. Thielke, Christian Secker, Helmut SchlaadORCiDGND, Patrick Theato |
|---|---|
| DOI: | https://doi.org/10.1002/marc.201500502 |
| ISSN: | 1022-1336 |
| ISSN: | 1521-3927 |
| Title of parent work (English): | Macromolecular rapid communications |
| Publisher: | Wiley-VCH |
| Place of publishing: | Weinheim |
| Publication type: | Article |
| Language: | English |
| Year of first publication: | 2016 |
| Publication year: | 2016 |
| Release date: | 2020/03/22 |
| Tag: | biomaterials; crystallization; electrospinning; polypeptoids; thermoresponsive |
| Volume: | 37 |
| Number of pages: | 5 |
| First page: | 100 |
| Last Page: | 104 |
| Funding institution: | Max Planck Society |
| Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie |
| Peer review: | Referiert |
