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Risk factors for dementia diagnosis in German primary care practices

  • Background: Dementia is a psychiatric condition the development of which is associated with numerous aspects of life. Our aim was to estimate dementia risk factors in German primary care patients. Methods: The case-control study included primary care patients (70-90 years) with first diagnosis of dementia (all-cause) during the index period (01/2010-12/2014) (Disease Analyzer, Germany), and controls without dementia matched (1:1) to cases on the basis of age, sex, type of health insurance, and physician. Practice visit records were used to verify that there had been 10 years of continuous follow-up prior to the index date. Multivariate logistic regression models were fitted with dementia as a dependent variable and the potential predictors. Conclusions: Risk factors for dementia found in this study are consistent with the literature. Nevertheless, the associations between statin, PPI and antihypertensive drug use, and decreased risk of dementia need further investigations.

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Author details:Anke BookerGND, Louis E. C. Jacob, Michael Armin RappORCiDGND, Jens Bohlken, Karel Kostev
DOI:https://doi.org/10.1017/S1041610215002082
ISSN:1041-6102
ISSN:1741-203X
Pubmed ID:https://pubmed.ncbi.nlm.nih.gov/26744954
Title of parent work (English):International psychogeriatrics
Publisher:Cambridge Univ. Press
Place of publishing:New York
Publication type:Article
Language:English
Year of first publication:2016
Publication year:2016
Release date:2020/03/22
Tag:Alzheimer; dementia; risk factors; statins
Volume:28
Number of pages:7
First page:1059
Last Page:1065
Peer review:Referiert
Institution name at the time of the publication:Humanwissenschaftliche Fakultät / Exzellenzbereich Kognitionswissenschaften
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