Mechanical Properties of Aligned Nanotopologies for Directing Cellular Behavior
- Tailoring cell–surface interactions is important for the of design medical implants as well as regenerative medicine and tissue engineering materials. Here the single parameter system is transcended via translating hard nanotopology into soft polymeric hydrogel structures via hydrogel imprinting lithography. The response of these cells to the nanotopology of the same dimensions but with different mechanical properties displays unexpected behavior between “hard” tissue cells and “soft” tissue cells.
| Author details: | Qihui Zhou, Patrick Wuennemann, Philipp Till Kuhn, Joop de Vries, Marta Helmin, Alexander BökerORCiDGND, Theo G. van Kooten, Patrick van Rijn |
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| DOI: | https://doi.org/10.1002/admi.201600275 |
| ISSN: | 2196-7350 |
| Title of parent work (English): | Advanced materials interfaces |
| Publisher: | Wiley-Blackwell |
| Place of publishing: | Hoboken |
| Publication type: | Article |
| Language: | English |
| Year of first publication: | 2016 |
| Publication year: | 2016 |
| Release date: | 2020/03/22 |
| Volume: | 3 |
| Number of pages: | 10 |
| Funding institution: | China Scholarship Council [201406630003]; Graduate School Medical Sciences of the University Medical Center Groningen |
| Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie |
| Peer review: | Referiert |
