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Silicification of peptide-coated silver nanoparticles-A biomimetic soft chemistry approach toward chiral hybrid core-shell materials
- Silica and silver nanoparticles are relevant materials for new applications in optics, medicine, and analytical chemistry. We have previously reported the synthesis of pH responsive, peptide-templated, chiral silver nanoparticles. The current report shows that peptide-stabilized nanoparticles can easily be coated with a silica shell by exploiting the ability of the peptide coating to hydrolyze silica precursors such as TEOS or TMOS. The resulting silica layer protects the nanoparticles from chemical etching, allows their inclusion in other materials, and renders them biocompatible. Using electron and atomic force microscopy, we show that the silica shell thickness and the particle aggregation can be controlled simply by the reaction time. Small-angle X ray scattering confirms the Ag/peptide@silica core-shell structure. UV-vis and circular dichroism spectroscopy prove the conservation of the silver nanoparticle chirality upon silicification. Biological tests show that the biocompatibility in simple bacterial systems is significantlySilica and silver nanoparticles are relevant materials for new applications in optics, medicine, and analytical chemistry. We have previously reported the synthesis of pH responsive, peptide-templated, chiral silver nanoparticles. The current report shows that peptide-stabilized nanoparticles can easily be coated with a silica shell by exploiting the ability of the peptide coating to hydrolyze silica precursors such as TEOS or TMOS. The resulting silica layer protects the nanoparticles from chemical etching, allows their inclusion in other materials, and renders them biocompatible. Using electron and atomic force microscopy, we show that the silica shell thickness and the particle aggregation can be controlled simply by the reaction time. Small-angle X ray scattering confirms the Ag/peptide@silica core-shell structure. UV-vis and circular dichroism spectroscopy prove the conservation of the silver nanoparticle chirality upon silicification. Biological tests show that the biocompatibility in simple bacterial systems is significantly improved once a silica layer is deposited on the silver particles.…
Author details: | Philipp Graf, Alexandre Mantion, Andrea Haase, Andreas F. Thuenemann, Admir Masic, Wolfgang P. Meier, Andreas Luch, Andreas TaubertORCiDGND |
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DOI: | https://doi.org/10.1021/nn102969p |
ISSN: | 1936-0851 |
Title of parent work (English): | ACS nano |
Publisher: | American Chemical Society |
Place of publishing: | Washington |
Publication type: | Article |
Language: | English |
Year of first publication: | 2011 |
Publication year: | 2011 |
Release date: | 2017/03/26 |
Tag: | Ag/peptide@SiO(2) nanostructures; chiral nanoparticles; core-shell structures; peptide-templated materials; silver nanoparticles |
Volume: | 5 |
Issue: | 2 |
Number of pages: | 14 |
First page: | 820 |
Last Page: | 833 |
Funding institution: | Adolf-Martens e.V.; Alexander von Humboldt Foundation; Max Planck Society; Federal Ministry of Education and Research; Swiss National Science Foundation; University of Potsdam; Fonds der Chemischen Industrie; Bundesanstalt fur Materialforschung und -prufung; Bundesinstitut fur Risikobewertung; MPI of Colloids and Interfaces (Colloid Chemistry Department) |
Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie |
Peer review: | Referiert |