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Cognitive Function in Adolescent Patients with Anorexia Nervosa and Unipolar Affective Disorders

  • Studies have shown impairments in cognitive function among adult patients with anorexia nervosa (AN) and affective disorders (AD). The association between cognitive dysfunctions, AN and AD as well as the specificity for these psychiatric diagnoses remains unclear. Therefore, we examined cognitive flexibility and processing speed in 47 female adolescent patients with AN, 21 female adolescent patients with unipolar affective disorders and 48 female healthy adolescents. All participants completed a neuropsychological test battery. There were no significant group differences regarding cognitive function, except for psychomotor processing speed with poorer performance in patients with AN. A further analysis revealed that all groups performed with the normal range, although patients with AN were over represented in the poorest performing quartile. We found no severe cognitive impairments in either patient group. Nevertheless, belonging to the AN group contributed significantly to poor performances in neuropsychological tasks. Therefore, weStudies have shown impairments in cognitive function among adult patients with anorexia nervosa (AN) and affective disorders (AD). The association between cognitive dysfunctions, AN and AD as well as the specificity for these psychiatric diagnoses remains unclear. Therefore, we examined cognitive flexibility and processing speed in 47 female adolescent patients with AN, 21 female adolescent patients with unipolar affective disorders and 48 female healthy adolescents. All participants completed a neuropsychological test battery. There were no significant group differences regarding cognitive function, except for psychomotor processing speed with poorer performance in patients with AN. A further analysis revealed that all groups performed with the normal range, although patients with AN were over represented in the poorest performing quartile. We found no severe cognitive impairments in either patient group. Nevertheless, belonging to the AN group contributed significantly to poor performances in neuropsychological tasks. Therefore, we conclude that the risk for cognitive impairments is slightly higher for patients with AN. Copyright (c) 2015 John Wiley & Sons, Ltd and Eating Disorders Association.show moreshow less

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Author details:Lea Sarrar, Martin Holzhausen, Petra WarschburgerORCiDGND, Ernst Pfeiffer, Ulrike Lehmkuhl, Nora Schneider
DOI:https://doi.org/10.1002/erv.2425
ISSN:1072-4133
ISSN:1099-0968
Pubmed ID:https://pubmed.ncbi.nlm.nih.gov/26695683
Title of parent work (English):European eating disorders review : the professional journal of the Eating Disorders Associatio
Publisher:Wiley-Blackwell
Place of publishing:Hoboken
Publication type:Article
Language:English
Year of first publication:2016
Publication year:2016
Release date:2020/03/22
Tag:adolescents; anorexia nervosa; cognitive function; unipolar affective disorders
Volume:24
Number of pages:9
First page:232
Last Page:240
Peer review:Referiert
Institution name at the time of the publication:Humanwissenschaftliche Fakultät / Exzellenzbereich Kognitionswissenschaften
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