Thomas Kiefer, Dorothea Krahl, Kathrin Osthoff, Peter Thuss-Patience, Jörg Bunse, Ulrich Adam, Marc H. Jansen, Rudolf Ott, Robert Pfitzmann, Matthias Pross, Thomas Kohlmann, Georg Daeschlein, Hermann Buhlert, Heinz Völler, Carsten Hirt
- After surgical treatment of cancer of the esophagus or the esophagogastric junction we observed steatorrhea, which is so far seldom reported. We analyzed all patients treated in our rehabilitation clinic between 2011 and 2014 and focused on the impact of surgery on digestion of fat. Reported steatorrhea was anamnestic, no pancreatic function test was made. Here we show the results from 51 patients. Twenty-three (45%) of the patients reported steatorrhea. Assuming decreased pancreatic function pancreatic enzyme replacement therapy (PERT) was started or modified during the rehabilitation stay (in the following called STEA(+)). These patients were compared with the patients without steatorrhea and without PERT (STEA(-)). Maximum weight loss between surgery and rehabilitation start was 18 kg in STEA(+) patient and 15.3 kg in STEA(-) patients. STEA(+) patients gained more weight under PERT during the rehabilitation phase (3 wk) than STEA(-) patients without PERT (+1.0 kg vs. -0.3 kg, P = 0.032). We report for the first time, that patientsAfter surgical treatment of cancer of the esophagus or the esophagogastric junction we observed steatorrhea, which is so far seldom reported. We analyzed all patients treated in our rehabilitation clinic between 2011 and 2014 and focused on the impact of surgery on digestion of fat. Reported steatorrhea was anamnestic, no pancreatic function test was made. Here we show the results from 51 patients. Twenty-three (45%) of the patients reported steatorrhea. Assuming decreased pancreatic function pancreatic enzyme replacement therapy (PERT) was started or modified during the rehabilitation stay (in the following called STEA(+)). These patients were compared with the patients without steatorrhea and without PERT (STEA(-)). Maximum weight loss between surgery and rehabilitation start was 18 kg in STEA(+) patient and 15.3 kg in STEA(-) patients. STEA(+) patients gained more weight under PERT during the rehabilitation phase (3 wk) than STEA(-) patients without PERT (+1.0 kg vs. -0.3 kg, P = 0.032). We report for the first time, that patients after cancer related esophageal surgery show anamnestic signs of exocrine pancreas insufficiency and need PERT to gain body weight.…
MetadatenAuthor details: | Thomas Kiefer, Dorothea Krahl, Kathrin Osthoff, Peter Thuss-PatienceGND, Jörg Bunse, Ulrich AdamORCiD, Marc H. Jansen, Rudolf Ott, Robert PfitzmannGND, Matthias Pross, Thomas KohlmannGND, Georg DaeschleinGND, Hermann Buhlert, Heinz VöllerORCiDGND, Carsten HirtORCiD |
---|
DOI: | https://doi.org/10.1080/01635581.2017.1374419 |
---|
ISSN: | 0163-5581 |
---|
ISSN: | 1532-7914 |
---|
Pubmed ID: | https://pubmed.ncbi.nlm.nih.gov/28945459 |
---|
Title of parent work (English): | Nutrition and cancer : an international journal |
---|
Publisher: | Routledge, Taylor & Francis Group |
---|
Place of publishing: | Abingdon |
---|
Publication type: | Article |
---|
Language: | English |
---|
Date of first publication: | 2017/09/25 |
---|
Publication year: | 2017 |
---|
Release date: | 2022/03/31 |
---|
Volume: | 70 |
---|
Issue: | 1 |
---|
Number of pages: | 4 |
---|
First page: | 69 |
---|
Last Page: | 72 |
---|
Funding institution: | Department of Medical Oncology of the Klinik am See, Rudersdorf, Berlin |
---|
Organizational units: | Humanwissenschaftliche Fakultät / Strukturbereich Kognitionswissenschaften / Department Sport- und Gesundheitswissenschaften |
---|
DDC classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
---|
Peer review: | Referiert |
---|