• Deutsch

University Logo

  • Home
  • Search
  • Browse
  • Submit
  • Sitemap
Schließen

Refine

Has Fulltext

  • no (1)
  • yes (1)

Author

  • Kohn, Barbara (2)
  • Neumann, Konrad (2)
  • Raila, Jens (2)
  • Schmiedchen, Bettina (2)
  • Schweigert, Florian J. (2)
  • Stumpff, Friederike (2)
  • Passlack, Nadine (1)
  • Paßlack, Nadine (1)
  • Zentek, Juergen (1)
  • Zentek, Jürgen (1)
+ more

Year of publication

  • 2016 (2)

Document Type

  • Article (1)
  • Postprint (1)

Language

  • English (2)

Is part of the Bibliography

  • yes (2)

Keywords

  • FGF23 (1)
  • chronic kidney-disease (1)
  • deficiency (1)
  • dogs (1)
  • growth-factor 23 (1)
  • hypercalciuria (1)
  • parathyroid-hormone (1)
  • phosphorus (1)
  • secretion (1)
  • urinary ph (1)
+ more

Institute

  • Institut für Ernährungswissenschaft (1)
  • Mathematisch-Naturwissenschaftliche Fakultät (1)

2 search hits

  • 1 to 2
  • BibTeX
  • CSV
  • RIS
  • XML
  • 10
  • 20
  • 50
  • 100

Sort by

  • Year
  • Year
  • Title
  • Title
  • Author
  • Author
Impact of increasing dietary calcium levels on calcium excretion and vitamin D metabolites in the blood of healthy adult cats (2016)
Paßlack, Nadine ; Schmiedchen, Bettina ; Raila, Jens ; Schweigert, Florian J. ; Stumpff, Friederike ; Kohn, Barbara ; Neumann, Konrad ; Zentek, Jürgen
Background Dietary calcium (Ca) concentrations might affect regulatory pathways within the Ca and vitamin D metabolism and consequently excretory mechanisms. Considering large variations in Ca concentrations of feline diets, the physiological impact on Ca homeostasis has not been evaluated to date. In the present study, diets with increasing concentrations of dicalcium phosphate were offered to ten healthy adult cats (Ca/phosphorus (P): 6.23/6.02, 7.77/7.56, 15.0/12.7, 19.0/17.3, 22.2/19.9, 24.3/21.6 g/kg dry matter). Each feeding period was divided into a 10-day adaptation and an 8-day sampling period in order to collect urine and faeces. On the last day of each feeding period, blood samples were taken. Results Urinary Ca concentrations remained unaffected, but faecal Ca concentrations increased (P < 0.001) with increasing dietary Ca levels. No effect on whole and intact parathyroid hormone levels, fibroblast growth factor 23 and calcitriol concentrations in the blood of the cats were observed. However, the calcitriol precursors 25(OH)D-2 and 25(OH)D-3, which are considered the most useful indicators for the vitamin D status, decreased with higher dietary Ca levels (P = 0.013 and P = 0.033). Increasing dietary levels of dicalcium phosphate revealed an acidifying effect on urinary fasting pH (6.02) and postprandial pH (6.01) (P < 0.001), possibly mediated by an increase of urinary phosphorus (P) concentrations (P < 0.001). Conclusions In conclusion, calcitriol precursors were linearly affected by increasing dietary Ca concentrations. The increase in faecal Ca excretion indicates that Ca homeostasis of cats is mainly regulated in the intestine and not by the kidneys. Long-term studies should investigate the physiological relevance of the acidifying effect observed when feeding diets high in Ca and P.
Impact of Increasing Dietary Calcium Levels on Calcium Excretion and Vitamin D Metabolites in the Blood of Healthy Adult Cats (2016)
Passlack, Nadine ; Schmiedchen, Bettina ; Raila, Jens ; Schweigert, Florian J. ; Stumpff, Friederike ; Kohn, Barbara ; Neumann, Konrad ; Zentek, Juergen
Background Dietary calcium (Ca) concentrations might affect regulatory pathways within the Ca and vitamin D metabolism and consequently excretory mechanisms. Considering large variations in Ca concentrations of feline diets, the physiological impact on Ca homeostasis has not been evaluated to date. In the present study, diets with increasing concentrations of dicalcium phosphate were offered to ten healthy adult cats (Ca/phosphorus (P): 6.23/6.02, 7.77/7.56, 15.0/12.7, 19.0/17.3, 22.2/19.9, 24.3/21.6 g/kg dry matter). Each feeding period was divided into a 10-day adaptation and an 8-day sampling period in order to collect urine and faeces. On the last day of each feeding period, blood samples were taken. Results Urinary Ca concentrations remained unaffected, but faecal Ca concentrations increased (P < 0.001) with increasing dietary Ca levels. No effect on whole and intact parathyroid hormone levels, fibroblast growth factor 23 and calcitriol concentrations in the blood of the cats were observed. However, the calcitriol precursors 25(OH)D-2 and 25(OH)D-3, which are considered the most useful indicators for the vitamin D status, decreased with higher dietary Ca levels (P = 0.013 and P = 0.033). Increasing dietary levels of dicalcium phosphate revealed an acidifying effect on urinary fasting pH (6.02) and postprandial pH (6.01) (P < 0.001), possibly mediated by an increase of urinary phosphorus (P) concentrations (P < 0.001). Conclusions In conclusion, calcitriol precursors were linearly affected by increasing dietary Ca concentrations. The increase in faecal Ca excretion indicates that Ca homeostasis of cats is mainly regulated in the intestine and not by the kidneys. Long-term studies should investigate the physiological relevance of the acidifying effect observed when feeding diets high in Ca and P.
  • 1 to 2

OPUS4 Logo  KOBV Logo  OAI Logo  DINI Zertifikat 2007  OA Netzwerk Logo

    • Publication server
    • University Bibliography
    • University Library
    • Policy
    • Contact
    • Imprint
    • Privacy Policy
    • Accessibility

    Login