Refine
Has Fulltext
- no (1)
Year of publication
- 2016 (1)
Document Type
- Article (1) (remove)
Language
- English (1)
Is part of the Bibliography
- yes (1)
Keywords
- poly(ether imide) microparticles (1) (remove)
Institute
- Institut für Chemie (1) (remove)
A high cell viability of around 99 +/- 18% and 99 +/- 5% was observed when THP-1 cells were cultured in the presence of aqueous extracts of the PEI microparticles in medium A and medium B respectively. The obtained microscopic data suggested that PEI particle extracts have no significant effect on cell death, oxidative stress or differentiation to macrophages. It was further found that the investigated proinflammatory markers in THP-1 cells were not up-regulated. These results are promising with regard to the biocompatibility of PEI microparticles and in a next step the hemocompatibility of the microparticles will be examined.