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Two sesquiterpenes, corymbolone and mustakone, isolated from the chloroform extract of the rhizomes of Cyperus articulatus, exhibited significant anti-plasmodial properties. Mustakone was approximately ten times more active than corymbolone against the sensitive strains of the Plasmodium falciparum.
The quantification of phosphate bound to the C6 and C3 positions of glucose residues in starch has received increasing interest since the importance of starch phosphorylation for plant metabolism was discovered. The method described here is based on the observation that the isobaric compounds glucose-6-phosphate (Glc6P) and glucose-3- phosphate (Glc3P) exhibit significantly different fragmentation patterns in negative ion electrospray tandem mass spectrometry (MS/MS). A simple experiment involving collision-induced dissociation (CID) MS2 spectra of the sample and the two reference substances Glc3P and Glc6P permitted the quantification of the relative amounts of the two compounds in monosaccharide mixtures generated by acid hydrolysis of starch. The method was tested on well-characterized potato tuber starch. The results are consistent with those obtained by NMR analysis. In contrast to NMR, however, the presented method is fast and can be performed on less than 1 mg of starch. Starch samples of other origins exhibiting a variety of phosphorylation degrees were analyzed to assess the sensitivity and robustness of the method.
Network approach to supply chain management : terms, scope of issues and lines of development
(2009)
This article argues that a pamphlet entitled "A Letter Sent to General Monk" (1660) has been wrongly attributed to the English republican Henry Neville (1619-94). Instead, the pamphlet was more likely written by a representative of the Presbyterian faction shortly before the restoration of the Stuart monarchy in 1660.
Henry Neville and English republican culture in the seventeenth century : dreaming of another game
(2009)
Henry Neville and English Republican Culture in the Seventeenth Century is the first full-length study of the republican Henry Neville in his many facets as country gentleman, politician, political thinker, rebel and libeller. It traces the development of Neville's political thought from the English Civil Wars to the Exclusion Crisis and beyond, while also challenging the way in which the history of ideas has been conceptualised in recent years by discussing Neville's political theory alongside his lesser known libels, shams and poetry. The book also challenges an established view of Neville based on his collaboration with the better-known philosopher James Harrington and shows Neville as a political thinker in his own right. While studies of early modern English republicanism tend to focus on the Interregnum, Neville's Plato redivivus, which promoted a restructuring of the political order, was only published after the 1660 Restoration of the monarchy. This study therefore draws attention to long-term continuities in English republican thought and introduces the concept of anti-patriarchalism to focus on what Neville and other republicans writing before 1649 or after 1660 had in common. They shared their opposition to tyranny, not monarchy, and aimed to limit the discretionary powers of the executive - a concern which links the debates between the Long Parliament and the King of 1641 to Neville's proposals to limit the powers of the Crown in 1681. The author's engagement with Neville's reputation as an atheist and crypto-Catholic also sheds new light on the role of religion in republican thought.