Refine
Has Fulltext
- no (53)
Year of publication
Language
- English (53)
Is part of the Bibliography
- yes (53)
Keywords
- radiation mechanisms: non-thermal (15)
- gamma rays: general (11)
- galaxies: active (10)
- gamma rays: galaxies (10)
- ISM: supernova remnants (6)
- acceleration of particles (6)
- cosmic rays (4)
- gamma-rays: galaxies (4)
- ISM: clouds (3)
- galaxies: jets (3)
- gamma rays: stars (3)
- BL Lacertae objects: general (2)
- BL Lacertae objects: individual: PKS 2155-304 (2)
- ISM: individual objects: G338.3-0.0 (2)
- X-rays: binaries (2)
- astroparticle physics (2)
- errata, addenda (2)
- gamma rays: ISM (2)
- infrared: diffuse background (2)
- pulsars: general (2)
- relativistic processes (2)
- BL Lacertae objects: individual (Mrk 501) (1)
- BL Lacertae objects: individual (PG 1553+113) (1)
- BL Lacertae objects: individual: 1ES 1312-423 (1)
- BL Lacertae objects: individual: 1ES 2322-409 (1)
- BL Lacertae objects: individual: AP Librae (1)
- BL Lacertae objects: individual: PKS 0301-243 (1)
- BL Lacertae objects: individual: PKS 0447-439 (1)
- BL Lacertae objects: individual: SHBL J001355.9-185406 (1)
- BL Lacertae objects: individual: lES 0229+200 (1)
- BL Lacertae objects: individual: lES 1101-232 (1)
- ISM: individual objects (SNR G338.3-0.0, SNR G338.5+0.1) (1)
- ISM: individual objects: Crab nebula (1)
- ISM: individual objects: HESS J1832-093 (1)
- ISM: individual objects: Puppis A (1)
- ISM: individual objects: SNR G1.9+0.3 (1)
- ISM: individual objects: SNR G22.7-0.2 (1)
- ISM: individual objects: SNR G330.2+1.0 (1)
- ISM: magnetic fields (1)
- Organic chemistry (1)
- Photochemistry (1)
- Physical chemistry (1)
- Theoretical chemistry (1)
- World Cancer Research Fund/American Institute for Cancer Research Recommendations (1)
- X-rays: general (1)
- X-rays: individuals: G15.4+0.1 (1)
- X-rays: stars (1)
- binaries: general (1)
- black hole physics (1)
- carbon sequestration (1)
- climate change (1)
- climatic debt (1)
- colorectal neoplasm (1)
- convection (1)
- cosmic background radiation (1)
- dark matter detectors (1)
- dark matter experiments (1)
- deforestation (1)
- diffuse radiation (1)
- diffusion (1)
- dwarfs galaxies (1)
- forest management (1)
- galaxies: distances and redshifts (1)
- galaxies: individual (M 87) (1)
- galaxies: magnetic fields (1)
- galaxies: nuclei (1)
- gamma ray detectors (1)
- gamma rays: general(HESS J0632+057, VER J0633+057) (1)
- gamma-ray burst: individual (GRB 170817A) (1)
- gamma-ray burst: individual: GRB 100621A (1)
- gamma-rays: ISM (1)
- gamma-rays: general (1)
- globular clusters: general (1)
- gravitational lensing: strong (1)
- gravitational waves (1)
- greenhouse gas emissions (1)
- intergalactic medium (1)
- livestock (1)
- methods: observational (1)
- pulsars: individual: PSR B0833-45 (1)
- pulsars: individual: PSR B1259-63 (1)
- quasars: individual: 3C 279 (1)
- quasars: individual: PKS 1510-089 (1)
- range shifts (1)
- risk factors (1)
- silvopastoral systems (1)
- stars: individual: 1FGL J1018.6-5856 (1)
- stars: individual: LS 2883 (1)
- stars: winds, outflows (1)
- supernovae: general (1)
- supernovae: individual: HESS J1818-154 (1)
- targeted metabolomics (1)
- understory (1)
The photochemical ring-opening of 1,3-cyclohexadiene imaged by ultrafast electron diffraction
(2019)
The ultrafast photoinduced ring-opening of 1,3-cyclohexadiene constitutes a textbook example of electrocyclic reactions in organic chemistry and a model for photobiological reactions in vitamin D synthesis. Although the relaxation from the photoexcited electronic state during the ring-opening has been investigated in numerous studies, the accompanying changes in atomic distance have not been resolved. Here we present a direct and unambiguous observation of the ring-opening reaction path on the femtosecond timescale and subangstrom length scale using megaelectronvolt ultrafast electron diffraction. We followed the carbon-carbon bond dissociation and the structural opening of the 1,3-cyclohexadiene ring by the direct measurement of time-dependent changes in the distribution of interatomic distances. We observed a substantial acceleration of the ring-opening motion after internal conversion to the ground state due to a steepening of the electronic potential gradient towards the product minima. The ring-opening motion transforms into rotation of the terminal ethylene groups in the photoproduct 1,3,5-hexatriene on the subpicosecond timescale.
Birth weight variation is influenced by fetal and maternal genetic and non-genetic factors, and has been reproducibly associated with future cardio-metabolic health outcomes. In expanded genome-wide association analyses of own birth weight (n = 321,223) and offspring birth weight (n = 230,069 mothers), we identified 190 independent association signals (129 of which are novel). We used structural equation modeling to decompose the contributions of direct fetal and indirect maternal genetic effects, then applied Mendelian randomization to illuminate causal pathways. For example, both indirect maternal and direct fetal genetic effects drive the observational relationship between lower birth weight and higher later blood pressure: maternal blood pressure-raising alleles reduce offspring birth weight, but only direct fetal effects of these alleles, once inherited, increase later offspring blood pressure. Using maternal birth weight-lowering genotypes to proxy for an adverse intrauterine environment provided no evidence that it causally raises offspring blood pressure, indicating that the inverse birth weight-blood pressure association is attributable to genetic effects, and not to intrauterine programming.
Metabolic signatures of healthy lifestyle patterns and colorectal cancer risk in a European cohort
(2020)
BACKGROUND & AIMS: Colorectal cancer risk can be lowered by adherence to the World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) guidelines. We derived metabolic signatures of adherence to these guidelines and tested their associations with colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition cohort.
METHODS: Scores reflecting adherence to the WCRF/AICR recommendations (scale, 1-5) were calculated from participant data on weight maintenance, physical activity, diet, and alcohol among a discovery set of 5738 cancer-free European Prospective Investigation into Cancer and Nutrition participants with metabolomics data. Partial least-squares regression was used to derive fatty acid and endogenous metabolite signatures of the WCRF/AICR score in this group. In an independent set of 1608 colorectal cancer cases and matched controls, odds ratios (ORs) and 95% CIs were calculated for colorectal cancer risk per unit increase in WCRF/AICR score and per the corresponding change in metabolic signatures using multivariable conditional logistic regression.
RESULTS: Higher WCRF/AICR scores were characterized by metabolic signatures of increased odd-chain fatty acids, serine, glycine, and specific phosphatidylcholines. Signatures were inversely associated more strongly with colorectal cancer risk (fatty acids: OR, 0.51 per unit increase; 95% CI, 0.29-0.90; endogenous metabolites: OR, 0.62 per unit change; 95% CI, 0.50-0.78) than the WCRF/AICR score (OR, 0.93 per unit change; 95% CI, 0.86-1.00) overall. Signature associations were stronger in male compared with female participants.
CONCLUSIONS: Metabolite profiles reflecting adherence to WCRF/AICR guidelines and additional lifestyle or biological risk factors were associated with colorectal cancer. Measuring a specific panel of metabolites representative of a healthy or unhealthy lifestyle may identify strata of the population at higher risk of colorectal cancer.
Colombia's agriculture, forestry and other land use sector accounts for nearly half of its total greenhouse gas (GHG) emissions. The importance of smallholder deforestation is comparatively high in relation to its regional counterparts, and livestock agriculture represents the largest driver of primary forest depletion. Silvopastoral systems (SPSs) are presented as agroecological solutions that synergistically enhance livestock productivity, improve local farmers' livelihoods and hold the potential to reduce pressure on forest conversion. The department of Caquetá represents Colombia's most important deforestation hotspot. Targeting smallholder livestock farms through survey data, in this work we investigate the GHG mitigation potential of implementing SPSs for smallholder farms in this region. Specifically, we assess whether the carbon sequestration taking place in the soil and biomass of SPSs is sufficient to offset the per-hectare increase in livestock GHG emissions resulting from higher stocking rates. To address these questions we use data on livestock population characteristics and historic land cover changes reported from a survey covering 158 farms and model the carbon sequestration occurring in three different scenarios of progressively-increased SPS complexity using the CO2 fix model. We find that, even with moderate tree planting densities, the implementation of SPSs can reduce GHG emissions by 2.6 Mg CO2e ha−1 yr−1 in relation to current practices, while increasing agriculture productivity and contributing to the restoration of severely degraded landscapes.
Ecological implications of extreme events footprints of the 2010earthquake along the chilean coast
(2012)
Deciphering ecological effects of major catastrophic events such as earthquakes, tsunamis, volcanic eruptions, storms and fires, requires rapid interdisciplinary efforts often hampered by a lack of pre-event data. Using results of intertidal surveys conducted shortly before and immediately after Chile's 2010 M-w 8.8 earthquake along the entire rupture zone (ca. 34-38 degrees S), we provide the first quantification of earthquake and tsunami effects on sandy beach ecosystems. Our study incorporated anthropogenic coastal development as a key design factor. Ecological responses of beach ecosystems were strongly affected by the magnitude of land-level change. Subsidence along the northern rupture segment combined with tsunami-associated disturbance and drowned beaches. In contrast, along the co-seismically uplifted southern rupture, beaches widened and flattened increasing habitat availability. Post-event changes in abundance and distribution of mobile intertidal invertebrates were not uniform, varying with land-level change, tsunami height and coastal development. On beaches where subsidence occurred, intertidal zones and their associated species disappeared. On some beaches, uplift of rocky subtidal substrate eliminated low intertidal sand beach habitat for ecologically important species. On others, unexpected interactions of uplift with man-made coastal armouring included restoration of upper and mid-intertidal habitat seaward of armouring followed by rapid colonization of mobile crustaceans typical of these zones formerly excluded by constraints imposed by the armouring structures. Responses of coastal ecosystems to major earthquakes appear to vary strongly with land-level change, the mobility of the biota and shore type. Our results show that interactions of extreme events with human-altered shorelines can produce surprising ecological outcomes, and suggest these complex responses to landscape alteration can leave lasting footprints in coastal ecosystems.
Recent global warming is acting across marine, freshwater, and terrestrial ecosystems to favor species adapted to warmer conditions and/or reduce the abundance of cold-adapted organisms (i.e., "thermophilization" of communities). Lack of community responses to increased temperature, however, has also been reported for several taxa and regions, suggesting that "climatic lags" may be frequent. Here we show that microclimatic effects brought about by forest canopy closure can buffer biotic responses to macroclimate warming, thus explaining an apparent climatic lag. Using data from 1,409 vegetation plots in European and North American temperate forests, each surveyed at least twice over an interval of 12-67 y, we document significant thermophilization of ground-layer plant communities. These changes reflect concurrent declines in species adapted to cooler conditions and increases in species adapted to warmer conditions. However, thermophilization, particularly the increase of warm-adapted species, is attenuated in forests whose canopies have become denser, probably reflecting cooler growing-season ground temperatures via increased shading. As standing stocks of trees have increased in many temperate forests in recent decades, local microclimatic effects may commonly be moderating the impacts of macroclimate warming on forest understories. Conversely, increases in harvesting woody biomass-e.g., for bioenergy-may open forest canopies and accelerate thermophilization of temperate forest biodiversity.
Context. On March 4, 2013 the Fermi-EAT and AGILE reported a flare from the direction of the Crab nebula in which the high-energy (HE; E > 100 MeV) flux was six times above its quiescent level. Simultaneous observations in other energy bands give us hints about the emission processes during the flare episode and the physics of pulsar wind nebulae in general.
Aims. We search for variability in the emission of the Crab nebula at very-high energies (VHF,; E > 100 GeV), using contemporaneous data taken with the H.E.S.S. array of Cherenkov telescopes.
Methods. Observational data taken with the H.E.S.S. instrument on five consecutive days during the flare were analysed for the flux and spectral shape of the emission from the Crab nebula. Night-wise light curves are presented with energy thresholds of 1 TeV and 5 TeV.
Results. The observations conducted with H.E.S.S. on March 6 to March 10, 2013 show no significant changes in the flux. They limit the variation in the integral flux above 1 TeV to less than 63% and the integral flux above 5 TeV to less than 78% at a 95% confidence level.
Myriapods (e. g., centipedes and millipedes) display a simple homonomous body plan relative to other arthropods. All members of the class are terrestrial, but they attained terrestriality independently of insects. Myriapoda is the only arthropod class not represented by a sequenced genome. We present an analysis of the genome of the centipede Strigamia maritima. It retains a compact genome that has undergone less gene loss and shuffling than previously sequenced arthropods, and many orthologues of genes conserved from the bilaterian ancestor that have been lost in insects. Our analysis locates many genes in conserved macro-synteny contexts, and many small-scale examples of gene clustering. We describe several examples where S. maritima shows different solutions from insects to similar problems. The insect olfactory receptor gene family is absent from S. maritima, and olfaction in air is likely effected by expansion of other receptor gene families. For some genes S. maritima has evolved paralogues to generate coding sequence diversity, where insects use alternate splicing. This is most striking for the Dscam gene, which in Drosophila generates more than 100,000 alternate splice forms, but in S. maritima is encoded by over 100 paralogues. We see an intriguing linkage between the absence of any known photosensory proteins in a blind organism and the additional absence of canonical circadian clock genes. The phylogenetic position of myriapods allows us to identify where in arthropod phylogeny several particular molecular mechanisms and traits emerged. For example, we conclude that juvenile hormone signalling evolved with the emergence of the exoskeleton in the arthropods and that RR-1 containing cuticle proteins evolved in the lineage leading to Mandibulata. We also identify when various gene expansions and losses occurred. The genome of S. maritima offers us a unique glimpse into the ancestral arthropod genome, while also displaying many adaptations to its specific life history.