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- Article (94) (remove)
Language
- English (94)
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- yes (94)
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- Ionic liquids (5)
- ionic liquids (5)
- electrochemistry (4)
- silver nanoparticles (4)
- nanoparticles (3)
- oxidative stress (3)
- poly(lactic acid) (3)
- 3D printing (2)
- Alkylpyridinium salts (2)
- Kaolinite (2)
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- Institut für Chemie (94) (remove)
Shkilnyy, Andriy ; Gräf, Ralph ; Hiebl, Bernhard ; Neffe, Axel T. ; Friedrich, Alwin ; Hartmann, Juergen ; Taubert, Andreas
Covalently crosslinked PEI hydrogels are efficient templates for calcium phosphate mineralization in SBF. In contrast to the PEI hydrogels, non-crosslinked PEI does not lead to calcium phosphate nucleation and growth in SBF. The precipitate is a mixture of brushite and hydroxyapatite. The PEI/calcium phosphate composite material exhibits a sponge like morphology and a chemical composition that is interesting for implants. Cytotoxicity tests using Dictyostelium discoideum amoebae show that both the non-mineralized and mineralized hydrogels have a very low cytotoxicity. This suggests that next generation PEI hydrogels, where also the degradation products are non-toxic, could be interesting for biomedical applications.