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Since more and more business tasks are enabled by Artificial Intelligence (AI)-based techniques, the number of knowledge-intensive tasks increase as trivial tasks can be automated and non-trivial tasks demand human-machine interactions. With this, challenges regarding the management of knowledge workers and machines rise [9]. Furthermore, knowledge workers experience time pressure, which can lead to a decrease in output quality. Artificial Intelligence-based systems (AIS) have the potential to assist human workers in knowledge-intensive work. By providing a domain-specific language, contextual and situational awareness as well as their process embedding can be specified, which enables the management of human and AIS to ease knowledge transfer in a way that process time, cost and quality are improved significantly. This contribution outlines a framework to designing these systems and accounts for their implementation.