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- selection (8)
- signal transduction (8)
- site effects (8)
- snow (8)
- soil (8)
- spatial frequencies (8)
- starch metabolism (8)
- stars: activity (8)
- stars: emission-line, Be (8)
- statistics (8)
- surface chemistry (8)
- surface modification (8)
- suspended sediment (8)
- sustainable development (8)
- time-series (8)
- trends (8)
- ultrafast (8)
- virtual reality (8)
- vitamin A (8)
- water quality (8)
- ADHD (7)
- Algorithms (7)
- Anisotropy (7)
- Apoptosis (7)
- Aromaticity (7)
- Austria (7)
- Biomaterial (7)
- C. elegans (7)
- Capsella (7)
- Central Europe (7)
- Competition (7)
- Complex networks (7)
- Connectivity (7)
- Conversation Analysis (7)
- Crustal structure (7)
- Cytotoxicity (7)
- DNA damage (7)
- DNA radiation damage (7)
- Decision-making (7)
- Dirac operator (7)
- E. coli (7)
- East African Rift System (7)
- Eutrophication (7)
- Fokus (7)
- Forschungsprojekte (7)
- Fredholm property (7)
- Future SOC Lab (7)
- Galaxien (7)
- Gender (7)
- Geochemistry (7)
- Geologie (7)
- Geschäftsprozessmanagement (7)
- Global change (7)
- Gravitationswellen (7)
- Greenland (7)
- Hertzsprung-Russell and C-M diagrams (7)
- Higher education (7)
- In-Memory Technologie (7)
- Indian Summer Monsoon (7)
- Interoception (7)
- Inverse theory (7)
- Kalman filter (7)
- Kohlenstoff (7)
- LCSM (7)
- Leguminosae (7)
- LiDAR (7)
- Longitudinal study (7)
- Mekong Delta (7)
- Molecular dynamics (7)
- Molecularly imprinted polymers (7)
- Molybdenum cofactor (7)
- Monsoon (7)
- Monsun (7)
- Morphology (7)
- Multicore Architekturen (7)
- Muscle strength (7)
- NICS (7)
- Netzwerke (7)
- Nutrition (7)
- Palaeoclimate (7)
- Patterns (7)
- Phosphorus (7)
- Phylogeography (7)
- Physical activity (7)
- Phytoplankton (7)
- Prediction (7)
- Prosodie (7)
- Prosody (7)
- Protein (7)
- Pseudomonas aeruginosa (7)
- RIXS (7)
- Remote sensing (7)
- Seasonality (7)
- Soil (7)
- Soil moisture (7)
- Solanaceae (7)
- Spain (7)
- Sprachverarbeitung (7)
- Starch metabolism (7)
- Subduktion (7)
- Survey (7)
- Switzerland (7)
- TAVI (7)
- Tectonics (7)
- Thermokarst (7)
- Tien Shan (7)
- Uncertainty (7)
- Unsicherheit (7)
- Unsicherheiten (7)
- Vesikel (7)
- Visualisierung (7)
- Vulnerabilität (7)
- Walking (7)
- Water quality (7)
- X-rays: ISM (7)
- Youth (7)
- acquisition (7)
- adolescent (7)
- aggregation (7)
- allostatic load (7)
- amygdala (7)
- arithmetic (7)
- binaries: eclipsing (7)
- birth weight (7)
- bystander (7)
- cAMP (7)
- calibration (7)
- carbon cycle (7)
- cardiovascular diseases (7)
- catalogs (7)
- cell adhesion (7)
- cellulose (7)
- charge generation (7)
- chemistry (7)
- chemotaxis (7)
- child (7)
- circadian clock (7)
- circulation (7)
- circumstellar matter (7)
- cities (7)
- climate impacts (7)
- climate-change mitigation (7)
- cluster expansion (7)
- coastal erosion (7)
- community (7)
- community ecology (7)
- comparison (7)
- complex systems (7)
- complexes (7)
- control (7)
- convection (7)
- coronary artery disease (7)
- cortisol (7)
- cyber aggression (7)
- cytotoxicity (7)
- defense (7)
- density (7)
- design thinking (7)
- diet (7)
- dietary patterns (7)
- digital health (7)
- discrepancy principle (7)
- distribution (7)
- disturbance (7)
- duplicate detection (7)
- ecological modelling (7)
- ecosystem functioning (7)
- energy (7)
- energy policy (7)
- ensemble Kalman filter (7)
- enzyme (7)
- enzyme catalysis (7)
- experiments (7)
- extinction (7)
- extraction (7)
- extreme events (7)
- extreme rainfall (7)
- fatty acids (7)
- films (7)
- first passage time (7)
- flood (7)
- flow (7)
- fluorescence microscopy (7)
- food webs (7)
- frequency (7)
- function (7)
- functional magnetic resonance imaging (7)
- galaxies (7)
- galaxies: dwarf (7)
- galaxies: starburst (7)
- gender differences (7)
- gene flow (7)
- geochemistry (7)
- geophysics (7)
- globalization (7)
- grain size (7)
- graphene (7)
- heart (7)
- heterogeneous catalysis (7)
- home range (7)
- human behaviour (7)
- human impact (7)
- identity (7)
- imaging (7)
- imaging spectroscopy (7)
- immobilization (7)
- inference (7)
- infrared: stars (7)
- insect (7)
- insula (7)
- international organizations (7)
- interoceptive awareness (7)
- isotopes (7)
- jumping (7)
- kinematics (7)
- land-use change (7)
- last glacial maximum (7)
- lipid metabolism (7)
- low-energy electrons (7)
- malnutrition (7)
- mechanisms (7)
- memory retrieval (7)
- metabolite profiling (7)
- methane (7)
- microbial ecology (7)
- minerals (7)
- mobility (7)
- modality (7)
- multilingualism (7)
- natural language processing (7)
- natural products (7)
- neuroplasticity (7)
- nuclear lamina (7)
- numerical simulations (7)
- organic matter (7)
- orthography (7)
- oscillations (7)
- pH (7)
- pain (7)
- palaeoecology (7)
- paleoecology (7)
- parafoveal processing (7)
- parameter estimation (7)
- parliamentary government (7)
- pathogens (7)
- perceptual span (7)
- planetary nebulae: general (7)
- planets and satellites: rings (7)
- plant diversity (7)
- plasmonics (7)
- policy (7)
- porous materials (7)
- predator-prey dynamics (7)
- preview benefit (7)
- productivity (7)
- pronoun resolution (7)
- prosodic boundary cues (7)
- proteasome (7)
- pulsars: general (7)
- quality (7)
- quantification (7)
- recombination (7)
- repair (7)
- representation (7)
- reproducibility (7)
- retinol (7)
- roughness (7)
- secular trend (7)
- seismic hazard (7)
- sexual scripts (7)
- shape-memory effect (7)
- silicon (7)
- size (7)
- social rejection (7)
- solar wind (7)
- sorption (7)
- stabile Isotope (7)
- stars: late-type (7)
- sunspots (7)
- surfactants (7)
- tVNS (7)
- taxonomy (7)
- time series (7)
- transfer (7)
- transition (7)
- treeline (7)
- trunk (7)
- urbanization (7)
- verification (7)
- visualization (7)
- weather (7)
- wh-in-situ (7)
- wh-questions (7)
- working memory capacity (7)
- yellow flags (7)
- youth sports (7)
- AFM (6)
- Adipositas (6)
- Ageing (6)
- Alaska (6)
- Alps (6)
- Anisotropy effect (6)
- Anpassung (6)
- Antibiotikaresistenz (6)
- Aphasie (6)
- Arbeitsgedächtnis (6)
- Arsenolipids (6)
- BMI (6)
- Bakterien (6)
- Balance (6)
- Bayesian data analysis (6)
- Bewegungsökologie (6)
- Big Data (6)
- Bioelectrocatalysis (6)
- Biogenic amine (6)
- Biophysik (6)
- Blockcopolymere (6)
- C-reactive protein (6)
- CO2 (6)
- Chytridiomycota (6)
- Click chemistry (6)
- Colombia (6)
- Computational modelling (6)
- Coping (6)
- Copper (6)
- Data assimilation (6)
- Deep learning (6)
- Design (6)
- Design Thinking (6)
- Dezentralisierung (6)
- Digitalisierung (6)
- Disturbance (6)
- Dynamic NMR (6)
- EEG/ERP (6)
- Emotions (6)
- Energy (6)
- Flood risk (6)
- Fluorescence spectroscopy (6)
- Gammastrahlungsastronomie (6)
- Gene-environment interaction (6)
- Genomics (6)
- Groundwater (6)
- H II regions (6)
- HIREC (6)
- ISM: kinematics and dynamics (6)
- Insurance (6)
- Interaction (6)
- Interest (6)
- Israel (6)
- Japan (6)
- Judaism (6)
- Klimaänderung (6)
- Künstliche Intelligenz (6)
- Lake Van (6)
- Land use change (6)
- Language acquisition (6)
- Lasers (6)
- Levy flights (6)
- Local Group (6)
- Longitudinal (6)
- Lysiphlebus fabarum (6)
- Magnetismus (6)
- Magnetohydrodynamik (6)
- Mandarin Chinese (6)
- Massenspektrometrie (6)
- Mental arithmetic (6)
- Meta-analysis (6)
- Methane (6)
- Microcystis aeruginosa (6)
- Microtubules (6)
- Mobility (6)
- Modell (6)
- Monitoring (6)
- Mortality (6)
- Movement (6)
- NASH (6)
- Namibia (6)
- Neotektonik (6)
- Neuroenhancement (6)
- Neurotoxicity (6)
- Norway (6)
- O-antigen (6)
- Optimization (6)
- Oxygen heterocycles (6)
- PBPK (6)
- Paläoklimatologie (6)
- Paris Agreement (6)
- Perception (6)
- Perceptual span (6)
- Phenotypic plasticity (6)
- Phonons (6)
- Photosynthese (6)
- Poecilia mexicana (6)
- Polyelektrolyte (6)
- Polymerchemie (6)
- Polymers (6)
- Population genetics (6)
- Predictors (6)
- Prenatal stress (6)
- Prevalence (6)
- Prevention (6)
- Prozessmodellierung (6)
- Prunus avium L. (6)
- Pyrenees (6)
- Quasare (6)
- Raman (6)
- Reinforcement learning (6)
- Reliability (6)
- Resistance training (6)
- Return to work (6)
- Rheologie (6)
- Rheology (6)
- Ring current effect (6)
- SDS-PAGE (6)
- Schadensmodellierung (6)
- Seesedimente (6)
- Seismology (6)
- Sentinel-1 (6)
- Sexual scripts (6)
- Sexual selection (6)
- Smalltalk (6)
- Soil erosion (6)
- Speech perception (6)
- Sphingosine 1-phosphate (6)
- Stable isotopes (6)
- Sternentwicklung (6)
- Stretch-shortening cycle (6)
- Subduction zone processes (6)
- Svalbard (6)
- Synthesis (6)
- TMS (6)
- TRMM (6)
- Taxonomy (6)
- Theoretical seismology (6)
- Theory (6)
- Thermochronologie (6)
- Time reference (6)
- Time series analysis (6)
- Topography (6)
- Toxicity (6)
- Transformation (6)
- Transkriptionsfaktoren (6)
- USA (6)
- United States (6)
- Variability (6)
- Vegetation (6)
- Vietnam (6)
- Vorhersage (6)
- Water (6)
- Westerlies (6)
- Wind erosion (6)
- World Bank (6)
- Zinc (6)
- acid ceramidase (6)
- admixture (6)
- age of acquisition (6)
- air pollution (6)
- alexithymia (6)
- algorithms (6)
- alignment (6)
- animal movement (6)
- anthropometry (6)
- antioxidants (6)
- arctic (6)
- attitudes (6)
- bicameralism (6)
- biodegradable polymers (6)
- black holes (6)
- bryophytes (6)
- business processes (6)
- carbon dioxide (6)
- change (6)
- change detection (6)
- chloroplast (6)
- co-limitation (6)
- coherence (6)
- colonialism (6)
- community effect (6)
- corruption (6)
- costs (6)
- crown compounds (6)
- crystal-structure (6)
- cyber victimization (6)
- cyber-physical systems (6)
- cytoskeleton (6)
- data (6)
- depressive symptoms (6)
- diabetic nephropathy (6)
- dielectrophoresis (6)
- diffuse radiation (6)
- digital education (6)
- domestication (6)
- droughts (6)
- dust (6)
- dust, extinction (6)
- early warning (6)
- eclogite (6)
- ecohydrology (6)
- effectiveness (6)
- efficient (6)
- eicosapentaenoic acid (6)
- electrons (6)
- electrostatic interactions (6)
- elementary particles (6)
- energy storage (6)
- engagement (6)
- english (6)
- entropy (6)
- environmental change (6)
- enzymes (6)
- exercise therapy (6)
- extension (6)
- fNIRS (6)
- fabrication (6)
- facilitation (6)
- fertilization (6)
- first passage (6)
- floodplain (6)
- fluorescence correlation spectroscopy (6)
- formal semantics (6)
- galaxies: abundances (6)
- galaxy evolution (6)
- gamma-ray astronomy (6)
- gamma-rays: general (6)
- gas (6)
- gelatin (6)
- general relativity (6)
- genes (6)
- geodynamics (6)
- geology (6)
- giving-up density (6)
- global warming (6)
- grammar (6)
- gravity (6)
- habitat (6)
- habituation (6)
- heterocycles (6)
- history and philosophy of astronomy (6)
- holocene (6)
- hybridization capture (6)
- hydrolysis (6)
- immigration (6)
- impacts (6)
- infancy (6)
- injury (6)
- institutions (6)
- interfaces (6)
- introgression (6)
- invasive species (6)
- kosmische Strahlung (6)
- leadership (6)
- life history (6)
- linagliptin (6)
- lithosphere (6)
- macrophytes (6)
- magnetism (6)
- maximal isometric Adaptive Force (6)
- meaning (6)
- measurement (6)
- mechanism (6)
- media violence (6)
- melt inclusions (6)
- mental simulation (6)
- metaanalysis (6)
- metabolic networks (6)
- metabolites (6)
- methods: analytical (6)
- miRNA (6)
- micelles (6)
- microbial communities (6)
- microtubules (6)
- molecular modeling (6)
- molecular motors (6)
- muscle (6)
- muscle power (6)
- neotectonics (6)
- neurodegeneration (6)
- next generation sequencing (6)
- nonergodicity (6)
- nuclear envelope (6)
- nucleus (6)
- numerical development (6)
- organic photovoltaics (6)
- organization (6)
- overweight (6)
- oxygen (6)
- p53 (6)
- palaeoclimate (6)
- parameters (6)
- participation (6)
- pattern formation (6)
- perturbation (6)
- phase transition (6)
- phase transitions (6)
- phenology (6)
- phonetics (6)
- phosphate (6)
- photoelectron spectroscopy (6)
- phylogenetic diversity (6)
- piezoelectricity (6)
- plant (6)
- plants (6)
- plyometric training (6)
- political equality (6)
- polyelectrolytes (6)
- polystyrene (6)
- polyzwitterions (6)
- population density (6)
- porosity (6)
- porous carbon (6)
- postural stability (6)
- pregnancy (6)
- presidential government (6)
- projections (6)
- propensity score matching (6)
- protein-protein interaction (6)
- radical polymerization (6)
- rainfall (6)
- rat (6)
- reciprocal class (6)
- reduction (6)
- reflection (6)
- reproduction (6)
- residual stress (6)
- restoration (6)
- retinol-binding protein 4 (6)
- rheology (6)
- risk factor (6)
- saccades (6)
- salinity gradient (6)
- salivary gland (6)
- scattering (6)
- scrambling (6)
- sediment transport (6)
- selenium (6)
- self-concept (6)
- self-healing (6)
- self-regulation (6)
- silver nanoparticles (6)
- soccer (6)
- social comparison (6)
- socioeconomic status (6)
- sodium (6)
- software engineering (6)
- solar cells (6)
- speed (6)
- standardization (6)
- star formation (6)
- stars: horizontal-branch (6)
- stars: kinematics and dynamics (6)
- stars: magnetic fields (6)
- stimuli-sensitive polymers (6)
- stroke (6)
- sulfite oxidase (6)
- support vector machine (6)
- systematic literature review (6)
- teaching (6)
- techniques: image processing (6)
- technology (6)
- thaliana (6)
- therapist competence (6)
- thermokarst (6)
- thermoresponsive polymers (6)
- tomato (6)
- tomography (6)
- topography (6)
- tracking (6)
- trade-offs (6)
- training adaptation (6)
- traits (6)
- transcriptional memory (6)
- ultrafast dynamics (6)
- uncertainty analysis (6)
- unemployment (6)
- uplift (6)
- user experience (6)
- variation (6)
- ventral striatum (6)
- violence (6)
- visions of democracy (6)
- water management (6)
- weight loss (6)
- world literature (6)
- zebrafish (6)
- 3D point clouds (5)
- 3D visualization (5)
- AC electrokinetics (5)
- ALAN (5)
- Absorption (5)
- Ackerschmalwand (5)
- African Humid Period (5)
- Aftercare (5)
- Agency (5)
- Algeria (5)
- Alterung (5)
- Amygdala (5)
- Ancient DNA (5)
- Animal personality (5)
- Antwortmengenprogrammierung (5)
- Arsenic-containing hydrocarbons (5)
- Asian monsoon (5)
- Assessment (5)
- Asteraceae (5)
- Atmosphäre (5)
- Autocorrelation (5)
- Basketball (5)
- Bayesian inversion (5)
- Big Five (5)
- Bilingualism (5)
- Biodiversity Exploratories (5)
- Biodiversity exploratories (5)
- Biofilm (5)
- Bioinformatik (5)
- Biosensors (5)
- Black Sea (5)
- Block copolymers (5)
- Blockcopolymer (5)
- Blood (5)
- Bodenfeuchte (5)
- Boric acid (5)
- Boron exposure (5)
- Bose-Einstein condensation (5)
- Brassicaceae (5)
- Cardiovascular diseases (5)
- Caribbean (5)
- Cattle (5)
- Cayley Graph (5)
- Cell polarity (5)
- Child (5)
- Chitooligosaccharides (5)
- Chloroplast (5)
- Cognitive control (5)
- Cold War (5)
- Community assembly (5)
- Conservation (5)
- Cost-effectiveness (5)
- Cue-based retrieval (5)
- Cultural diversity (5)
- Cyanobakterien (5)
- Cystic fibrosis (5)
- DRD4 (5)
- Datenassimilation (5)
- Datenbank (5)
- Decision making (5)
- Dexamethasone (5)
- Dictyostelium discoideum (5)
- Duplikaterkennung (5)
- EPR (5)
- ERA5 (5)
- EU (5)
- Earthquake hazards (5)
- East Germany (5)
- Ecotoxicology (5)
- Electrical conductivity (5)
- Electropolymerization (5)
- Ellenberg indicator values (5)
- Elliptic complexes (5)
- Embodiment (5)
- Emulsion (5)
- Entwicklung (5)
- Environmental sciences (5)
- Europa (5)
- European hare (5)
- Europäische Union (5)
- Extraction (5)
- Extreme events (5)
- Eye movement (5)
- Feature selection (5)
- Fetal programming (5)
- Fire-bellied toad (5)
- Flood (5)
- Flow cytometry (5)
- Fluorescence imaging (5)
- Food quality (5)
- Frailty (5)
- Free Group (5)
- Functional ankle instability (5)
- G-protein-coupled receptor (5)
- GIS (5)
- Galaxy: center (5)
- Geodynamik (5)
- Geomagnetic field (5)
- Geomagnetism (5)
- Geomorphology (5)
- Geophysik (5)
- Geostatistics (5)
- German colonialism (5)
- Glucose (5)
- Gold nanoparticles (5)
- Governance (5)
- Grassland (5)
- Ground reaction force (5)
- HVSR (5)
- Habitat fragmentation (5)
- Heart rate variability (5)
- Hebrew (5)
- Heterocycles (5)
- Holding isometric muscle action (5)
- Hypertension (5)
- IAT (5)
- IR-MALDI (5)
- ISM: jets and outflows (5)
- ISM: lines and bands (5)
- ISM: magnetic fields (5)
- Imaging (5)
- Individual-based models (5)
- Induced seismicity (5)
- Information (5)
- Insect (5)
- Intervention (5)
- Ionosphere (5)
- Janus emulsions (5)
- Jugendliche (5)
- Kant (5)
- Kinder (5)
- Klimapolitik (5)
- Kosmologie (5)
- L2 processing (5)
- LC–MS/MS (5)
- Lactams (5)
- Lactones (5)
- Lakes (5)
- Land-use intensity (5)
- Landslides (5)
- Langmuir monolayer (5)
- Language production (5)
- Larix (5)
- Late Pleistocene (5)
- Leadership (5)
- Life history (5)
- Lonar Lake (5)
- MQTT (5)
- Magnetostratigraphy (5)
- Magnetotellurik (5)
- Measurement (5)
- Mechanotendography (5)
- Memory (5)
- Menderes Massif (5)
- Mental disorders (5)
- Metathesis (5)
- Middle East (5)
- Mikrofluidik (5)
- Mindfulness (5)
- Mitochondrial DNA (5)
- Moco biosynthesis (5)
- Molekulardynamik (5)
- Movement ecology (5)
- Mycobacterium tuberculosis (5)
- NAFLD (5)
- NE81 (5)
- NLP (5)
- NW Argentina (5)
- Nachhaltigkeit (5)
- Nanostruktur (5)
- Navier-Stokes equations (5)
- Neo-Tethys (5)
- Nepal (5)
- Network clustering (5)
- Neumann problem (5)
- Neural networks (5)
- Northeast German Basin (5)
- Nutrients (5)
- O2C spectrophotometer (5)
- Open innovation (5)
- Organic Chemistry (5)
- Organic solar cells (5)
- PCA (5)
- PUFA (5)
- Palaeolimnology (5)
- Paleoclimatology (5)
- Paleolimnology (5)
- Palynology (5)
- Peptides (5)
- Permian (5)
- Perturbation (5)
- Ph.D. retreat (5)
- Phase transitions (5)
- Photochemistry (5)
- Plant functional types (5)
- Plio-Pleistocene (5)
- Population dynamics (5)
- Postural control (5)
- Priming (5)
- Process (5)
- Process mining (5)
- Productivity (5)
- Proteins (5)
- Pushing isometric muscle action (5)
- Python (5)
- Quantum chemical calculations (5)
- R&D (5)
- RAFT polymerization (5)
- RNA (5)
- RNA-Seq (5)
- ROS (5)
- Residual stress (5)
- Resonant inelastic X-ray scattering (5)
- Risk assessment (5)
- Ruthenium (5)
- Röntgenbeugung (5)
- SRTM (5)
- STM (5)
- SWAT (5)
- SWIM (5)
- Saturn (5)
- Scattering (5)
- School (5)
- Sediment (5)
- Seismic tomography (5)
- Selenium (5)
- Semantic Web (5)
- Sensorimotor training (5)
- Sentence reading (5)
- Sexual aggression (5)
- Simulations (5)
- Solanum lycopersicum (5)
- Solanum tuberosum (5)
- Solar cells (5)
- Sphingosine-1-phosphate (5)
- Stochastische Prozesse (5)
- Strahlungstransport (5)
- Strontium isotope stratigraphy (5)
- Systematic review (5)
- Tarim Basin (5)
- Tectonic geomorphology (5)
- Temperature (5)
- TerraceM (5)
- Theorie (5)
- Thin film (5)
- Throughfall (5)
- Ti-6Al-4V (5)
- Tian Shan (5)
- Time series (5)
- Trust (5)
- Turbulenz (5)
- Twitter (5)
- Ultrafast X-ray diffraction (5)
- Unsicherheitsanalyse (5)
- Variation (5)
- Verifikation (5)
- Vietnamese (5)
- Vulnerability (5)
- Wasser (5)
- Word frequency (5)
- Workplace (5)
- X-ray absorption (5)
- X-ray absorption spectroscopy (5)
- X-ray photoelectron spectroscopy (5)
- X-ray spectroscopy (5)
- XPS (5)
- abstract concepts (5)
- academic achievement (5)
- academic self-concept (5)
- accumulation (5)
- action observation (5)
- activated carbon (5)
- acute kidney injury (5)
- administration (5)
- administrative reforms (5)
- agreement (5)
- agricultural landscapes (5)
- alcohol consumption (5)
- amino acids (5)
- anger (5)
- anger regulation (5)
- angiogenesis (5)
- animacy (5)
- anthracenes (5)
- antibiotic resistance (5)
- antidepressants (5)
- antiplasmodial (5)
- apoptosis (5)
- aquatic fungi (5)
- arenes (5)
- articulation (5)
- assembly (5)
- attribution (5)
- autocorrelation (5)
- avoidance (5)
- bacteriophage (5)
- basin (5)
- behaviour (5)
- benzaldehyde (5)
- bias (5)
- big data (5)
- biomimetic sensors (5)
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- biosynthesis (5)
- blockchain (5)
- boundary value problems (5)
- brain (5)
- burnout (5)
- capitalism (5)
- carbon cycling (5)
- cardiorespiratory fitness (5)
- cartel (5)
- catalysts (5)
- cell-based assay (5)
- change of direction (5)
- charge-transfer (5)
- chemical modification (5)
- child development (5)
- child language (5)
- children and adolescents (5)
- chitosan (5)
- citation analysis (5)
- cloud (5)
- coarticulation (5)
- coffee by-products (5)
- cognitive development (5)
- collapse (5)
- comets: general (5)
- communities (5)
- community effect on height (5)
- comorbidity (5)
- composition (5)
- computational linguistics (5)
- computed tomography (5)
- computer vision (5)
- confinement (5)
- consistency (5)
- constraints (5)
- construct validity (5)
- construction (5)
- contrast (5)
- conversation analysis (5)
- copolymers (5)
- corpus study (5)
- cosmology: theory (5)
- crisis management (5)
- cultural diversity (5)
- cytosine methylation (5)
- databases (5)
- definite pseudoclefts (5)
- dependencies (5)
- developmental dyscalculia (5)
- dialogue (5)
- digital learning (5)
- digital rock physics (5)
- digital technologies (5)
- direct electron transfer (5)
- disaster risk reduction (5)
- dogs (5)
- drop jump (5)
- drug delivery (5)
- duration (5)
- dynamic NMR (5)
- dyslexia (5)
- earthquakes (5)
- ecological speciation (5)
- economics (5)
- economy (5)
- electronic structure (5)
- electropolymerization (5)
- elevated CO2 (5)
- ellipsis processing (5)
- emotion recognition (5)
- employment (5)
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- energy expenditure (5)
- entity resolution (5)
- environment (5)
- environmental DNA (5)
- equatorial electrojet (5)
- ethics (5)
- evapotranspiration (5)
- event coincidence analysis (5)
- exoplanets (5)
- expectation (5)
- expertise (5)
- eye movement (5)
- eye-movement control (5)
- federalism (5)
- feedback (5)
- ferroelectret (5)
- field (5)
- filaments (5)
- financial markets (5)
- first-passage time (5)
- fish (5)
- flood risk management (5)
- flooding (5)
- foraging (5)
- foreland basin (5)
- fragmentation (5)
- fruit (5)
- future (5)
- galaxies: haloes (5)
- galaxies: halos (5)
- galaxies: nuclei (5)
- geometric Brownian motion (5)
- glacier (5)
- global (5)
- globular clusters: general (5)
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- habitat use (5)
- heart rate variability (5)
- height (5)
- hemoglobin amount (5)
- herbivory (5)
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- heterosis (5)
- high pressure (5)
- homeostasis (5)
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- hypochondriasis (5)
- ice-sheet (5)
- implicit (5)
- inclusive education (5)
- income (5)
- infection (5)
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- information (5)
- inheritance (5)
- institutional change (5)
- institutional design (5)
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- inter-individual differences (5)
- intraspecific trait variation (5)
- inundation (5)
- ionosphere (5)
- island biogeography (5)
- knowledge transfer (5)
- kosmogene Nuklide (5)
- landscape (5)
- lanthanides (5)
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- linear term (5)
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- molekulare Motoren (5)
- morphologically complex words (5)
- multiblock copolymer (5)
- multicore architectures (5)
- multiplicative noise (5)
- music (5)
- musicality (5)
- nanoparticle (5)
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- negation (5)
- neovascularization (5)
- network analysis (5)
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- neutron diffraction (5)
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- non-fullerene acceptors (5)
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- nucleation (5)
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- oxidation (5)
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- partial melting (5)
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- pathways (5)
- peptide (5)
- perceptual reorganization (5)
- periodization (5)
- permafrost degradation (5)
- permeability (5)
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- perpetrator (5)
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- race (5)
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- random diffusivity (5)
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- range shifts (5)
- real-time rendering (5)
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- record (5)
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- rejection sensitivity (5)
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- running (5)
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- savanna (5)
- scale development (5)
- scaling (5)
- sedaDNA (5)
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- selectivity (5)
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- semi-arid (5)
- sensitivity analysis (5)
- sensors (5)
- sentence production (5)
- sentiment analysis (5)
- service-oriented systems engineering (5)
- sex (5)
- shotgun sequencing (5)
- single-particle tracking (5)
- social (5)
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- social support (5)
- soil erosion (5)
- soil organic carbon (5)
- spatial autocorrelation (5)
- spatial cognition (5)
- spatial-distribution (5)
- species coexistence (5)
- species distribution models (5)
- spectra (5)
- speech motor control (5)
- sphingosine-1-phosphate (5)
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- tRNA (5)
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- thermal modeling (5)
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- tiefes Lernen (5)
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- top-down control (5)
- transcription (5)
- transcriptome (5)
- trend analysis (5)
- trust (5)
- tunneling (5)
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- ultraviolet: ISM (5)
- uncertainties (5)
- uncertainty quantification (5)
- upconversion (5)
- urban (5)
- validation study (5)
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- victim blame (5)
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- ökologische Modellierung (5)
- 2nd-language (4)
- 4 (4)
- ABC transporter (4)
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- accretion, accretion disks (4)
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- adiponectin (4)
- adjectives (4)
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- advanced dynamic flow (4)
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- agreement attraction (4)
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- coefficient (4)
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- cognitive modeling (4)
- collaboration (4)
- collaborative consumption (4)
- collagen (4)
- colloids (4)
- collusion (4)
- colonization (4)
- color (4)
- combat sports (4)
- common vole (4)
- community structure (4)
- competence (4)
- complexity (4)
- compliance (4)
- composites (4)
- computer-based training (4)
- concepts (4)
- conceptualization (4)
- conduct problems (4)
- conductivity (4)
- confocal microscopy (4)
- conjugated polymers (4)
- consequences (4)
- content-addressable memory (4)
- context (4)
- contracts (4)
- conversational agents (4)
- convolutional neural network (4)
- coping strategies (4)
- copper(II) (4)
- core (4)
- corrosion (4)
- counting (4)
- covariance (4)
- creep (4)
- crop production (4)
- cross-cultural comparison (4)
- crosslinking (4)
- cultural pluralism (4)
- cyberbullying victimization (4)
- cyclic voltammetry (4)
- cylindrospermopsin (4)
- cystic fibrosis (4)
- cytochrome c (4)
- data mining (4)
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- decarbonization (4)
- deformation (4)
- degenerative disc disease (4)
- demography (4)
- deposition (4)
- design (4)
- dictator game (4)
- differentiation (4)
- digital (4)
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- discourse production (4)
- diversification (4)
- dog (4)
- dopamine (4)
- dropout (4)
- drugs (4)
- dual-process (4)
- dyadic coping (4)
- dye removal (4)
- dynamic (4)
- dynamical models (4)
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- edge effect (4)
- electron paramagnetic resonance (4)
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- emissions (4)
- emotional expression (4)
- emulsion (4)
- endophytes (4)
- enhancement (4)
- entanglement (4)
- environmental filtering (4)
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- errata, addenda (4)
- ethnicity (4)
- eutrophication (4)
- evaluative study (4)
- evaporites (4)
- event-related brain potentials (4)
- evolutionary history (4)
- exercise intensity (4)
- experimental design (4)
- exploratory-behavior (4)
- eye-movement monitoring (4)
- face perception (4)
- family (4)
- fatty acid metabolism (4)
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- fault (4)
- feature selection (4)
- fence ecology (4)
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- fiction (4)
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- finger counting (4)
- firm performance (4)
- first language acquisition (4)
- first-passage (4)
- floral scent (4)
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- fluctuating light (4)
- fluctuations (4)
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- formal verification (4)
- fractional dynamics (4)
- frustration (4)
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- fundamental frequency (4)
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- galaxies: star formation (4)
- garden-path effect (4)
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- gene regulation (4)
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- geovisualization (4)
- global jets (4)
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- glomerular filtration rate (4)
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- glucosinolates (4)
- glutathione (4)
- grammaticalization (4)
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- graphs (4)
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- holding isometric muscle action (HIMA) (4)
- honey bee (4)
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- hybrid (4)
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- interest (4)
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- ionic strength (4)
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- shape (4)
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- discourse analysis (3)
- discourse parsing (3)
- dispersion (3)
- disposition (3)
- distress (3)
- distributed systems (3)
- divergent thinking (3)
- downscaling (3)
- downstep (3)
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- drought projections (3)
- drought stress (3)
- drug delivery system (3)
- drug discovery (3)
- drylands (3)
- dye (3)
- dyes (3)
- dynamic light scattering (3)
- dynamical model (3)
- dynamische Systeme (3)
- e-government (3)
- earthquake modeling (3)
- earthquake source observations (3)
- eastern south–central Andes (3)
- eating behavior (3)
- eating disorders (3)
- echocardiography (3)
- echolocation (3)
- eco-evolutionary feedbacks (3)
- eco-hydrological modelling (3)
- eco-hydrology (3)
- ecoevolutionary dynamics (3)
- ecological stoichiometry (3)
- econometrics (3)
- ecophysiology (3)
- ecosystem function (3)
- effect (3)
- ego depletion (3)
- elastic properties (3)
- elastomers (3)
- elbow breadth (3)
- electoral systems (3)
- electric fish (3)
- electrical muscle stimulation (3)
- electrical resistivity (3)
- electrochemical impedance spectroscopy (3)
- electrolytes (3)
- electromagnetic radiation (3)
- electron microscopy (3)
- electrophysiological evidence (3)
- elemental composition (3)
- elevated plus-maze (3)
- ellipsometry (3)
- elliptic complexes (3)
- embedded systems (3)
- emergency management (3)
- emotional intelligence (3)
- emotional valence (3)
- employment services (3)
- emulsion polymerization (3)
- encoding (3)
- end-stage kidney disease (3)
- endothelial cells (3)
- endothelin (3)
- endothelin-converting enzyme (3)
- endozoochory (3)
- endurance exercise (3)
- energy transfer (3)
- energy transition (3)
- energy-metabolism (3)
- enjoyment (3)
- ensemble prediction (3)
- enterprise systems (3)
- environmental economics (3)
- environmental pollution (3)
- envy (3)
- enzyme immobilization (3)
- enzymology (3)
- ephrin (3)
- episodic memory (3)
- epistemic modality (3)
- equality (3)
- equalizing and stabilizing mechanisms (3)
- equi-singular connections (3)
- equifinality (3)
- erythropoiesis (3)
- escherichia-coli (3)
- establishment (3)
- ethnic differences (3)
- ethnic identity (3)
- evaporation (3)
- event (3)
- eventology (3)
- everyday life (3)
- evolution equation (3)
- exchange (3)
- exercise adherence (3)
- exercise training (3)
- experience (3)
- experimental studies (3)
- exploitation (3)
- exploration (3)
- explosives (3)
- extracellular matrix (3)
- extraction and characterization methods (3)
- extremes (3)
- extremophiles (3)
- eye-voice span (3)
- face morphing (3)
- facial feedback (3)
- factor analysis (3)
- factor structure (3)
- faking (3)
- fault reactivation (3)
- faults (3)
- fermentation-related enzymes (3)
- ferroelectrets (3)
- fibers (3)
- fibrosis (3)
- figurative language (3)
- film (3)
- filter (3)
- financial time series (3)
- finite element modeling (3)
- fire (3)
- first-hitting time (3)
- fiscal policy (3)
- fitness consequences (3)
- fixation durations (3)
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- flavonoid (3)
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- flood hazard (3)
- flood hazards (3)
- flood loss (3)
- floodplain sedimentation (3)
- floodplains (3)
- flowering (3)
- fluctuation-dissipation theorem (3)
- fluid-rock interaction (3)
- fluorescence lifetime (3)
- flux (3)
- foam (3)
- food choice (3)
- food neophilia (3)
- food security (3)
- forecast (3)
- forest (3)
- forest structure (3)
- forestREplot (3)
- formal languages (3)
- formale Verifikation (3)
- formate dehydrogenase (3)
- formation damage (3)
- fracture (3)
- frailty (3)
- framework (3)
- frameworks (3)
- freedom (3)
- freedom restriction (3)
- frequency analysis (3)
- fricative (3)
- friendship (3)
- fsQCA (3)
- functional (3)
- functional capacity (3)
- functional dependencies (3)
- functional dependency (3)
- functionalization (3)
- fungal diversity (3)
- gait analysis (3)
- galaxies: fundamental parameters (3)
- galaxy structure (3)
- gallbladder cancer (3)
- garnet (3)
- gas adsorption (3)
- gels (3)
- gender inequality (3)
- gene duplication (3)
- gene family (3)
- gene regulatory network (3)
- generalizability (3)
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- genetic programming (3)
- genome assembly (3)
- genome scan (3)
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- geometry (3)
- geospatial data (3)
- geostatistics (3)
- geothermal (3)
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- glacial hazards (3)
- glacial lake outburst floods (3)
- glacial refugia (3)
- glaciers (3)
- glass (3)
- global environmental change (3)
- global monsoon (3)
- global surface warming (3)
- globular clusters: individual: NGC 6397 (3)
- glucan (3)
- glucocorticoid receptor (3)
- glycaemic control (3)
- glycogen (3)
- glycopolymers (3)
- goal frames (3)
- goblet cells (3)
- good governance (3)
- gradient boosting (3)
- gradient flow (3)
- grain-size distribution (3)
- grammatical illusion (3)
- granite (3)
- granitoids (3)
- graph constraints (3)
- graphite (3)
- graphomotor control (3)
- grassland (3)
- grasslands (3)
- green (3)
- green growth (3)
- green-green dilemma (3)
- gross primary production (3)
- ground reaction forces (3)
- ground-penetrating radar (3)
- grounded cognition (3)
- groundwater recharge (3)
- grouping (3)
- growth rate (3)
- guilt (3)
- habitat loss (3)
- hand (3)
- health behavior (3)
- heart rate (3)
- heat stress memory (3)
- heath potentials (3)
- hemispheric asymmetry (3)
- heterogene Katalyse (3)
- heterogene Photokatalyse (3)
- heterogeneous photocatalysis (3)
- heterostyly (3)
- heterotrophic bacteria (3)
- hierarchical clustering (3)
- high temperature (3)
- high-pressure (3)
- high-resolution record (3)
- high-sodium (3)
- hillslopes (3)
- hip (3)
- historiography (3)
- honeybee (3)
- hormones (3)
- hospitalization (3)
- hostile attribution bias (3)
- hoverflies (3)
- human capital (3)
- human rights (3)
- hybrid model (3)
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- hydrogen bonds (3)
- hydrogenation (3)
- hydrogeology (3)
- hydrological modeling (3)
- hydrological processes (3)
- hyperbolic tilings (3)
- hypersound (3)
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- hypothesis (3)
- hypoxia (3)
- iCheck (3)
- ice (3)
- ice sheet (3)
- identity management (3)
- ideology (3)
- image-based representation (3)
- imidazolium (3)
- imitation (3)
- immigrants (3)
- impact assessment (3)
- impedance spectroscopy (3)
- implicit association test (IAT) (3)
- implicit learning (3)
- in-service teacher training (3)
- inbreeding depression (3)
- incision (3)
- incremental graph pattern matching (3)
- indirect facilitation (3)
- indirect tests (3)
- individual (3)
- individual anaerobic threshold (3)
- individuelle Unterschiede (3)
- induced pluripotent stem cells (3)
- industry 4.0 (3)
- infant (3)
- inferences (3)
- infiltration (3)
- inflectional morphology (3)
- information integration (3)
- infrared: diffuse background (3)
- injection (3)
- inner magnetosphere (3)
- input frequency (3)
- insects (3)
- instrumental variables (3)
- intensification (3)
- intercultural competence (3)
- interface (3)
- interface engineering (3)
- interfacial recombination (3)
- interferometry (3)
- intergalaktisches Medium (3)
- interindividual differences (3)
- interleukin-8 (3)
- intermediate disturbance hypothesis (3)
- international bureaucracies (3)
- international law (3)
- international organisations (3)
- intervention locality (3)
- intonation units (3)
- intracellular-transport (3)
- intraclass correlation (3)
- intraspecific variation (3)
- intrinsically disordered proteins (3)
- invasion (3)
- inverse analysis (3)
- inverse micelles (3)
- inverse problem (3)
- inverse theory (3)
- ionogels (3)
- ionothermal synthesis (3)
- islands (3)
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- isotopic composition (3)
- isotopic tiling theory (3)
- iterative regularization (3)
- job satisfaction (3)
- job search (3)
- just transition (3)
- kana (3)
- kanji (3)
- kernel density estimation (3)
- kernel methods (3)
- kettle hole (3)
- kidney (3)
- kinetic instabilities (3)
- kognitive Modellierung (3)
- komplexe Systeme (3)
- komplexes Netzwerk (3)
- körperliche Fitness (3)
- l-cysteine desulfurase (3)
- lactate threshold (3)
- land cover change (3)
- land-use (3)
- landscape diversity (3)
- landscape homogenization (3)
- langevin equation (3)
- language comprehension (3)
- language contact (3)
- language courses (3)
- language processing (3)
- languages (3)
- large-scale (3)
- large-scale assessment (3)
- large-scale structure of Universe (3)
- last glacial period (3)
- late Holocene (3)
- latitude (3)
- latitudinal gradient (3)
- leaf (3)
- leaf development (3)
- leaf senescence (3)
- leaking (3)
- learning factories (3)
- learning styles (3)
- lesson evaluation (3)
- lexical development (3)
- lexical tones (3)
- life course (3)
- life-history traits (3)
- light intensity (irradiance) (3)
- limits (3)
- line: profiles (3)
- linear mixed models (3)
- linear programming (3)
- linearized gravity (3)
- lipid (3)
- lipidomics (3)
- liquid-phase catalysis (3)
- literacy acquisition (3)
- literatures of the world (3)
- liver metabolism (3)
- load (3)
- locus of control (3)
- logarithmic source condition (3)
- logic (3)
- lokale Anpassung (3)
- long-distance dispersal (3)
- losses (3)
- lower (3)
- lower thermosphere (3)
- lupin (3)
- lutein (3)
- lysosomal storage disorders (3)
- lysosome (3)
- mAb disposition (3)
- magnetic reconnection (3)
- magnetotactic bacteria (3)
- magnetotaktische Bakterien (3)
- magnitude estimation (3)
- maintenance of functional diversity (3)
- major depression (3)
- majority rule (3)
- marine terrace (3)
- marine terraces (3)
- mass index (3)
- mass media (3)
- mass wasting (3)
- massereiche Sterne (3)
- matching (3)
- mathematical modelling (3)
- mathematical precursor (3)
- media (3)
- media use (3)
- medicine (3)
- melatonin (3)
- memory and delay (3)
- mental imagery (3)
- mesocrystals (3)
- metabolic disease (3)
- metabolite (3)
- metagenomics (3)
- metal nanoparticles (3)
- metal nitrides (3)
- methodological quality (3)
- miRNAs (3)
- micro degree (3)
- micro-credential (3)
- microemulsion (3)
- microgel (3)
- microlensing (3)
- micronutrients (3)
- microwave irradiation (3)
- migrants (3)
- military culture (3)
- minimal pairs (3)
- minimax convergence rates (3)
- minorities (3)
- missing-VP effect (3)
- mitochondrial dysfunction (3)
- mitogenome (3)
- mitogenomes (3)
- mitosis (3)
- mittlere Kindheit (3)
- modal verbs (3)
- modality compatibility (3)
- model coupling (3)
- model transformation (3)
- model uncertainty (3)
- model-driven engineering (3)
- modellgetriebene Entwicklung (3)
- moderne jüdische Geschichte (3)
- modularity (3)
- molecular doping (3)
- molybdoenzyme (3)
- monoclonal antibody (3)
- monomer (3)
- monomers (3)
- mood (3)
- morpho-orthography (3)
- morphological decomposition (3)
- morphological priming (3)
- morphological structure (3)
- morphometrics (3)
- morphosyntax (3)
- motion capture (3)
- motor resonance (3)
- motor skills (3)
- motor system (3)
- movement kinematics (3)
- mowing (3)
- mu-DSC (3)
- multicultural policy (3)
- multiculturalism (3)
- multilevel modelling (3)
- multiobjective calibration (3)
- multiple stressors (3)
- multiscale analysis (3)
- multispectral (3)
- multivariate statistics (3)
- muscle action (3)
- muscle metabolism (3)
- musculoskeletal (3)
- musculoskeletal and neural physiological phenomena (3)
- music cognition (3)
- music perception (3)
- mutation (3)
- nanoclusters (3)
- nanocomposites (3)
- nanoelectrodes (3)
- nanoparticle dimers (3)
- nanoscale heat transfer (3)
- nanotriangles (3)
- naphthalenes (3)
- narrative (3)
- natal dispersal (3)
- natural habitats (3)
- naturalism (3)
- nature conservation (3)
- nearshore zone (3)
- need satisfaction (3)
- net ecosystem exchange (3)
- neural (3)
- neuromuscular adaptation (3)
- neuromuscular functionality (3)
- neuronal networks (3)
- neuroscience (3)
- neutral endopeptidase (3)
- neutron (3)
- new public management (3)
- niche and fitness differences (3)
- niche width (3)
- nitrogen limitation (3)
- noisy systems (3)
- nominalization (3)
- non-Langevin recombination (3)
- non-athletes (3)
- non-categoricity (3)
- nonfullerene acceptors (3)
- nonlinear (3)
- nonradiative voltage losses (3)
- nonstationarity (3)
- northern high latitudes (3)
- noun (3)
- novel ecosystems (3)
- novelty (3)
- nucleobases (3)
- number concepts (3)
- number processing (3)
- numerical modelling (3)
- numerical models (3)
- numerische Kognition (3)
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- nutrient retention (3)
- nutrient supply (3)
- nutritional ecology (3)
- oarsmen (3)
- object search (3)
- ocean heat uptake (3)
- offspring (3)
- oil palm (3)
- olivine (3)
- on-water performance (3)
- one-carbon metabolism (3)
- online discrimination (3)
- online disinhibition (3)
- online learning (3)
- online teaching (3)
- open (3)
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- open-circuit voltage (3)
- open-field (3)
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- operating systems (3)
- optical manipulation (3)
- optical spectroscopy (3)
- optimism (3)
- optische Fasern (3)
- organ size (3)
- organic electronics (3)
- organic solar cell (3)
- organic synthesis (3)
- organic-matter (3)
- organische Solarzellen (3)
- organisches Material (3)
- organosilica (3)
- origins (3)
- orogenic peridotite (3)
- orogeny (3)
- osteoclast (3)
- outcome (3)
- outcome measures (3)
- outcomes (3)
- outlier detection (3)
- overweight children (3)
- oxygen isotopes (3)
- oxygen reduction reaction (3)
- palaeolimnology (3)
- paleo-sediment (3)
- paleogenetics (3)
- paleovegetation (3)
- parafoveal (3)
- parafoveal-on-foveal effect (3)
- parallel processing (3)
- parameterization (3)
- parasitoid (3)
- parchment (3)
- particles (3)
- pasture (3)
- patient education (3)
- pea (3)
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- peak height velocity (3)
- peak torque (3)
- peatlands (3)
- peer influences (3)
- perceived stress (3)
- perception and action (3)
- performance information (3)
- performance management (3)
- performance measurement (3)
- periphyton (3)
- permafrost ecosystems (3)
- personality traits (3)
- perspective taking (3)
- phagocytosis (3)
- phase (3)
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- phase dynamics (3)
- phenomenology (3)
- phonological development (3)
- phonology (3)
- phosphatidylserine (3)
- photocurrent generation (3)
- photoelectron (3)
- photoionization (3)
- photon density wave spectroscopy (3)
- photosensitive surfactants (3)
- photoswitches (3)
- photosynthetic rate (3)
- physical aggression (3)
- physical conditioning human (3)
- phytolith (3)
- phytoplankton communities (3)
- piezoelectret (3)
- piezoelectrets (3)
- pigment composition (3)
- pitch angle (3)
- planets and satellites: individual (Saturn) (3)
- plant cell wall (3)
- plant invasion (3)
- plant science (3)
- plant volatiles (3)
- plant-plant interactions (3)
- plasma-membrane (3)
- plausibility (3)
- pluvial floods (3)
- plyometrics (3)
- pneumonia (3)
- point clouds (3)
- point-of-care (3)
- policy analysis (3)
- policy evaluation (3)
- policy-making (3)
- political ideology (3)
- poly(A) polymerase (3)
- poly(N-isopropylacrylamide) (3)
- poly(ether imide) (3)
- polyadenylation (3)
- polyesters (3)
- polyglycerol (3)
- polymer solar cells (3)
- polymersomes (3)
- polymorphism (3)
- polypeptide (3)
- polysulfobetaine (3)
- population growth rate (3)
- possessives (3)
- post-natal (3)
- potassium channel (3)
- potato (3)
- poverty (3)
- power spectral analysis (3)
- power spectrum (3)
- pp-wave solutions (3)
- pragmaticalisation (3)
- pre-activity (3)
- pre-natal (3)
- pre-service teachers (3)
- precaution (3)
- precision agriculture (3)
- predation risk (3)
- predator-prey (3)
- predator-prey model (3)
- prediction models (3)
- preference (3)
- prefixes (3)
- pressures (3)
- prevalence information (3)
- primary care (3)
- primary metabolism (3)
- primary school children (3)
- prior knowledge (3)
- privatization (3)
- probability (3)
- probability density function (3)
- probes (3)
- problem-solving (3)
- process (3)
- process analytical technology (3)
- process modeling (3)
- proliferation (3)
- prosocial (3)
- prosody processing (3)
- protein binding (3)
- protein restriction (3)
- protein search (3)
- protein self-assembly (3)
- protein-phenol interactions (3)
- proteomic analysis (3)
- protonation (3)
- prototype-willingness-model (3)
- psycho-oncology (3)
- psychological distress (3)
- psychopathology (3)
- psychopower (3)
- puberty (3)
- public good (3)
- public service delivery (3)
- public transport (3)
- pulling isometric muscle action (PIMA) (3)
- pump-probe (3)
- punishment (3)
- quality assurance (3)
- quantitative research (3)
- quantum dynamics (3)
- quantum friction (3)
- quantum optics (3)
- quantum thermodynamics (3)
- quasars (3)
- quasi-Fermi level splitting (3)
- questions (3)
- radial flow (3)
- radio continuum: stars (3)
- radiogenic isotopes (3)
- rainfall gradient (3)
- range dynamics (3)
- range of motion (3)
- range size (3)
- rate of torque development (3)
- reactance (3)
- reaction mechanisms (3)
- reading comprehension (3)
- real-time (3)
- rearrangement (3)
- recommendations (3)
- record linkage (3)
- recurrence quantification analysis (3)
- red meat (3)
- redox (3)
- redox chemistry (3)
- reference material (3)
- referential choice (3)
- refinement (3)
- reforms (3)
- refugee youth (3)
- regime shifts (3)
- regional development (3)
- regioselectivity (3)
- regression tree (3)
- reionization (3)
- relationship constellations (3)
- relationships (3)
- relative rank (3)
- religiosity (3)
- remission (3)
- remote sensing data (3)
- remote teaching (3)
- replacement (3)
- representation learning (3)
- reproducing kernel Hilbert space (3)
- requirements (3)
- research design (3)
- resolution (3)
- resonance energy-transfer (3)
- resurrection plants (3)
- return to work (3)
- reveals (3)
- reversible measure (3)
- reward (3)
- rhizosphere (3)
- rifting (3)
- ring current (3)
- ring current electrons (3)
- risk attitudes (3)
- risk aversion (3)
- risk communication (3)
- risk governance (3)
- risk management cycle (3)
- river (3)
- river floods (3)
- robbery (3)
- rodent (3)
- role-play (3)
- running mechanics (3)
- runoff generation (3)
- sACC (3)
- salinity (3)
- salt diffusion (3)
- sample preparation (3)
- sanctions (3)
- satellite data (3)
- scalability (3)
- scaled Brownian motion (3)
- scene perception (3)
- schwarze Löcher (3)
- science mapping (3)
- seawater (3)
- second language acquisition (3)
- second language processing (3)
- secondary metabolites (3)
- sedentary (3)
- sediment core (3)
- sediment dynamics (3)
- sediment routing (3)
- sedimentation (3)
- sediments (3)
- seed dispersal syndrome (3)
- seismic risk (3)
- seismisches Rauschen (3)
- self threat (3)
- self-assembled monolayers (3)
- self-objectification (3)
- self-organisation (3)
- self-regulated learning (3)
- self-similarity (3)
- semantic (3)
- sensor data (3)
- sensorimotor control (3)
- sensorimotor training (3)
- sentence parsing (3)
- separation (3)
- serine cycle (3)
- serum (3)
- sexual assault (3)
- sexual coercion (3)
- sexual violence (3)
- shallow structure hypothesis (3)
- shape-memory polymer (3)
- short-read mapping (3)
- sibilant (3)
- sick leave (3)
- sickness absence (3)
- signalling (3)
- silica (3)
- similarity (3)
- similarity-based interference (3)
- simulation model (3)
- simultaneous bilingualism (3)
- singularity (3)
- situated processes (3)
- size distribution (3)
- skeletal muscle (3)
- skeletal robustness (3)
- skew Brownian motion (3)
- smart materials (3)
- smartphone (3)
- soccer players (3)
- social environment (3)
- social network analysis (3)
- social reactivity (3)
- social valuation (3)
- sociality (3)
- sociolinguistics (3)
- sociometric status (3)
- sodium hydroxide etching (3)
- soft actuators (3)
- soft robotics (3)
- software development (3)
- soil hydrology (3)
- soil landscape (3)
- soil texture (3)
- sol-gel (3)
- solar powered light-emitting diode (3)
- solubility (3)
- solute transport (3)
- somatic variables (3)
- source parameters (3)
- spatial scales (3)
- spatially explicit (3)
- spatially explicit model (3)
- speaking children (3)
- special education (3)
- special educational needs (3)
- species assembly (3)
- species composition (3)
- species recognition (3)
- specific language impairment (3)
- specific surface area (3)
- specificity (3)
- spectroelectrochemistry (3)
- sphingomyelin (3)
- sphingosine (3)
- sphingosine kinase (3)
- spider silk (3)
- spin (3)
- star product (3)
- starch granule initiation (3)
- starch granule surface (3)
- starch granules (3)
- starch morphology (3)
- starch synthase (3)
- stars: (3)
- stars: coronae (3)
- stars: distances (3)
- stars: individual (WR 6) (3)
- stars: pre-main sequence (3)
- statins (3)
- statistical (3)
- statistical methods (3)
- stellar populations (3)
- stellar winds (3)
- stereoselectivity (3)
- stochastic bridge (3)
- stochastic processes (theory) (3)
- stochastic resonance (3)
- stochastische Prozesse (3)
- stokes shift (3)
- stopover (3)
- strategic uncertainty (3)
- strategies (3)
- stress-gradient hypothesis (3)
- strike-slip fault (3)
- student achievement (3)
- student exchange (3)
- students (3)
- study (3)
- study designs (3)
- subcellular localization (3)
- subjective well-being (3)
- submarine (3)
- substance use (3)
- substrate (3)
- succession (3)
- sufficiency (3)
- summer (3)
- sun (3)
- supercapacitors (3)
- supergene (3)
- supersaturated species coexistence (3)
- supervised machine learning (3)
- supramolecular chemistry (3)
- surface functionalization (3)
- surface treatment (3)
- surface-relief gratings (3)
- surfaces (3)
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- Laserstrahlschmelzen (2)
- Late Quaternary vegetation (2)
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- Lateinamerika (2)
- Latent Class Analysis (2)
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- Lateralization (2)
- Latino (2)
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- Learning analytics (2)
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- Rayleigh waves (2)
- Rb-Sr mineral isochrons (2)
- Reactive oxygen species (2)
- Real time (2)
- Realismus (2)
- Reanalysis (2)
- Rearing experiment (2)
- Rearrangement (2)
- Reasoning (2)
- Receiver functions (2)
- Rechenschaftspflicht (2)
- Recognition Memory (2)
- Recollection (2)
- Recombinase polymerase amplification (2)
- Recombination (2)
- Recurrence Plots (2)
- Red Cross (2)
- Redox (2)
- Redox marker (2)
- Redox polymer (2)
- Redoxreaktion (2)
- Redundancy (2)
- Reflectivity (2)
- Reflexion (2)
- Reflexionsseismik (2)
- Reflexives (2)
- Reflexivpronomen (2)
- Refugee Tales (2)
- Regionalization (2)
- Regularization (2)
- Regulatory focus (2)
- Regulierung (2)
- Rehearsal (2)
- Reinforcement Learning (2)
- Rekonstruktionsmethoden (2)
- Rekurrenzplot (2)
- Relapse (2)
- Relative clause (2)
- Relative clauses (2)
- Relativized Minimality (2)
- Release (2)
- Religiosity (2)
- Remote Sensing (2)
- Removable sets (2)
- Renal failure (2)
- Renal function (2)
- Renewable energy (2)
- Renewable resources (2)
- Reparaturen (2)
- Repeated sprint (2)
- Replication (2)
- Reproducibility (2)
- Reproducible benchmarking (2)
- Reproducing kernel Hilbert space (2)
- Republik Korea (2)
- ResNet (2)
- Reservoir Networks (2)
- Residual stresses (2)
- Resiliency (2)
- Resolved and unresolved sources as a function of wavelength (2)
- Resonances (2)
- Resource Competition (2)
- Ressourcenoptimierung (2)
- Resurvey (2)
- Retention (2)
- Reticulocytes (2)
- Retina (2)
- Retinyl esters (2)
- Revenue Autonomy (2)
- Rheic Ocean (2)
- Rhine River (2)
- Ribosome (2)
- Ribosome profiling (2)
- Richard Schomburgk (2)
- Riemannian manifold (2)
- Riesenvesikel (2)
- Riesz continuity (2)
- Ring tensiometry (2)
- Ring-opening polymerization (2)
- Rings (2)
- Rio Grande (2)
- Risiko (2)
- Risk factor (2)
- River Incision Model (2)
- River restoration (2)
- River-Basin (2)
- Robustness (2)
- Rodent (2)
- Rohstoffe (2)
- Role-playing (2)
- Romania (2)
- Roridula gorgonias (2)
- Rossby waves (2)
- Rossby-normal modes (2)
- Rotifier (2)
- Rougon-Macquart (2)
- Royden boundary (2)
- RpoS (2)
- RuBisCO (2)
- Rubisco (2)
- Rumelian Turkic (2)
- Rumpf (2)
- Run time analysis (2)
- Runge-Kutta methods (2)
- Running (2)
- Runtime analysis (2)
- Rural health (2)
- Russisch (2)
- Räuber-Beute (2)
- Röntgenstrahlung (2)
- S-XRF (2)
- SAMT (2)
- SAUR (2)
- SCED (2)
- SCFA (2)
- SCP (2)
- SD3 (2)
- SDG interactions (2)
- SEIRA spectroelectrochemistry (2)
- SELEX (2)
- SEPE (2)
- SERS enhancement factor (2)
- SFON (2)
- SHG (2)
- SIEM (2)
- SIMS (2)
- SIMS techniques (2)
- SIO₂ (2)
- SLA (2)
- SLI (2)
- SMARC (2)
- SOA (2)
- SOEP (2)
- SOPARSE (2)
- SOV language (2)
- SPARQL (2)
- SPB (2)
- SPDEs (2)
- SRT (2)
- SSW (2)
- STG decomposition (2)
- STG-Dekomposition (2)
- SUB1A (2)
- SWL (2)
- Saccade (2)
- Sahel (2)
- Sailfin molly (2)
- Sakkadendetektion (2)
- Salt Range (2)
- Salt pan (2)
- Salz (2)
- Salzschmelze-Templating (2)
- Samara (2)
- Sampling (2)
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- Sanierung (2)
- Santa-Barbara system (2)
- Saprolegnia (2)
- Saprolegniaceae (2)
- Sarcopenia (2)
- Satellite magnetics (2)
- Satellitenbilder (2)
- Satisfiability (2)
- Satzverständnis (2)
- Savanna ecology (2)
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- Savanne (2)
- Scalability (2)
- Scanning electron microscopy (2)
- Scattering theory (2)
- Scenario (2)
- Scenarios (2)
- Scene perception (2)
- Schaum (2)
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- Schrodinger equation (2)
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- Schwarmbeben (2)
- Schwarzes Loch (2)
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- Scientific discovery learning (2)
- Sclerochronology (2)
- Scotland (2)
- Scotophilus (2)
- Se (2)
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- Secularism (2)
- Secure Configuration (2)
- Sediment Flux (2)
- Sediment fingerprinting (2)
- Sediment geochemistry (2)
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- Sedimentary basin (2)
- Sedimentation (2)
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- Sediments (2)
- Sedimenttransport (2)
- Seed mass (2)
- Seesediment (2)
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- Seismotectonic segmentation (2)
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- Seismotektonik (2)
- Seitenverschiebung (2)
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- Selection (2)
- Selection vs. age-class forests (2)
- Selektivität (2)
- Selen (2)
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- Self-assembly (2)
- Self-concept (2)
- Self-harm (2)
- Self-organization (2)
- Self-reflection (2)
- Semantic preview benefit (2)
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- Semantics (2)
- Sensitivitätsanalyse (2)
- Sensor fusion (2)
- Sensors (2)
- Sensory perception (2)
- Sentence-picture matching (2)
- Sentinel 2 (2)
- Sentinel-1 InSAR (2)
- Sentinel-2 (2)
- Sequential instruction (2)
- Sequenzierung der nächsten Generation (2)
- Serine cycle (2)
- Service-Oriented Architecture (2)
- Service-Orientierte Architekturen (2)
- Service-oriented computing (2)
- Sesia Zone (2)
- Sexual Selection (2)
- Sexual conflict (2)
- Sexual dimorphism (2)
- Shadowgraphy (2)
- Shale gas (2)
- Shallow processing (2)
- Shame (2)
- Shannon diversity (2)
- Shannon entropy (2)
- Shape-memory (2)
- Shape-memory effect (2)
- Shape-memory polymer (2)
- Shear Zone (2)
- Shigella flexneri (2)
- Shockley-Queisser model (2)
- Shocks (2)
- Shona (2)
- Short‐term effect (2)
- Shotgun sequencing (2)
- Shoulder (2)
- Shrews (2)
- Si fractions (2)
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- Signal detection theory (2)
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- Signalling (2)
- Silicon isotopes (2)
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- Single nucleotide polymorphisms (2)
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- Skin (2)
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- Small (2)
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- Smoking (2)
- Smpd1 (2)
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- Sobo-Sise Island (2)
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- Social cues (2)
- Social functioning (2)
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- Spanish modal adverbs (2)
- Spanish verbs of cognitive attitude (2)
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- Spatial autocorrelation (2)
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- Speech Motor Control (2)
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- Sprachkontakt (2)
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- Strukturbildung (2)
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- Störungen (2)
- Subarctic North Pacific (2)
- Subject-verb agreement (2)
- Subjective well-being (2)
- Submarine permafrost (2)
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- Subsea permafrost (2)
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- Sun: UV radiation (2)
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- Synthesis and processing (2)
- SysML (2)
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- Säugetiere (2)
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- TACC (2)
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- TELEMAC-2D model (2)
- TGF-beta 1 (2)
- TIN (2)
- TLR signaling (2)
- TMR (2)
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- Tiredness (2)
- To learners in which of the following categories does your work apply (2)
- Toll and Imd pathways (2)
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- a priori (2)
- aberrations (2)
- ability differentiation (2)
- aboveground biomass (2)
- absolute (2)
- absorbtion fine-structure (2)
- abstraction (2)
- abundance (2)
- abuse cycles (2)
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- academy (2)
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- acclimation (2)
- accommodation (2)
- accountability dynamics (2)
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- accounting (2)
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- acids (2)
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- acquired thermotolerance (2)
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- adjustment (2)
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- aged (2)
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- agricultural landscape (2)
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- allgemeine Relativitätstheorie (2)
- allocation (2)
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- alphaherpesvirus (2)
- alpine (2)
- alps (2)
- altenuic acid (2)
- alternaria group (2)
- alternative rewards (2)
- alternative-set semantics (2)
- altertoxins (2)
- alumni work (2)
- amateur soccer players (2)
- ambient noise (2)
- ambiguities (2)
- ambiguity (2)
- ambiguity resolution (2)
- ambition (2)
- aminothiophenol (2)
- ammonia (2)
- ammonia synthesis (2)
- amoeboid motion (2)
- amorphous carbon (2)
- amorphous polymers (2)
- amplitude (2)
- amöboide Bewegung (2)
- anagogy (2)
- analytical framework for Participatory Educational Practices (2)
- analytical methods (2)
- anaphoric existence presupposition (2)
- anaphoricity (2)
- anatexis (2)
- ancestral remains (2)
- anchor peptides (2)
- ancient (2)
- and prediction (2)
- angiotensin receptor blockers (2)
- animal (2)
- animal and computational models (2)
- animal behavior (2)
- animal cognition (2)
- animal migration (2)
- animal models (2)
- anisotropic effects (2)
- ankles (2)
- anniversary issue (2)
- annotation (2)
- annotation projection (2)
- anomalous Brownian motion (2)
- anomaly detection (2)
- anorexia nervosa (2)
- antecedent choice (2)
- anterior PNP (2)
- anterior cruciate ligament (2)
- anthracene (2)
- anthropogenic food subsidies (2)
- anti-cancer drugs (2)
- anti-consumption (2)
- anti-genotoxicity (2)
- anti-inflammatory nutrition (2)
- anti-inflammatory therapy (2)
- anti-oxidant activity (2)
- anti-oxidative capacity (2)
- anti-oxidative response (2)
- antibiotic inactivation (2)
- antibiotics (2)
- antibody producing cell selection (2)
- anticancer drug (2)
- anticipation (2)
- antimicrobial peptide (2)
- antimicrobial peptides (2)
- antimicrobial polymers (2)
- antimicrobial resistance (2)
- antioxidant capacity (2)
- antonymy (2)
- anxiety disorder (2)
- anxiety sensitivity (2)
- anxiety-like behavior (2)
- apatite fission track (2)
- apis mellifera (2)
- apodemus-agrarius (2)
- apoplast (2)
- appetite (2)
- apple replant disease (2)
- applicant reactions (2)
- applicants for international protection (2)
- approximate differentiability (2)
- approximate methods (2)
- approximate number system (2)
- approximation (2)
- aptasensors (2)
- aquaculture (2)
- aquatic (2)
- aqueous dispersion (2)
- aquifer (2)
- arabidopsis thaliana (2)
- arable weeds (2)
- archaeology (2)
- archipelagic studies (2)
- archipelagic theory (2)
- arctic water bodies (2)
- area-based conservation (2)
- argon dating (2)
- argument structure (2)
- argumentation mining (2)
- aridification (2)
- arktische Tundra (2)
- aromaticity (2)
- array (2)
- arsenic (2)
- arsenious acid (2)
- arthropod (2)
- artificial intelligence for health (2)
- artificial light (2)
- artificial light at night (2)
- artificial light at night (ALAN) (2)
- artificial transcription factor (2)
- ascorbate (2)
- ascorbate peroxidase (2)
- assay (2)
- assembly factor (2)
- assembly processes (2)
- assembly rules (2)
- assignments (2)
- assimilation (2)
- associative learning (2)
- associative networks (2)
- astrobiology (2)
- astrocytes (2)
- astrometry (2)
- astronomical calibration (2)
- astronomical databases (2)
- astronomical databases: miscellaneous (2)
- asylum (2)
- asylum seekers (2)
- asymptotic behavior (2)
- asymptotic method (2)
- asynchronous video interviewing (2)
- athlete (2)
- athmospheric circulation (2)
- atmospheric blocking (2)
- atmospheric nitrogen deposition (2)
- atmospheric warming (2)
- atom chip (2)
- atom-surface interaction (2)
- atomic processes (2)
- atropisomerism (2)
- attachment styles (2)
- attitudes towards sexual coercion (2)
- attosecond phenomena (2)
- attraction errors (2)
- attribute assurance (2)
- auch (2)
- augmented-wave method (2)
- august 2002 (2)
- authentication (2)
- authoritarianism (2)
- authorship attribution (2)
- autism spectrum disorder (2)
- autogamy (2)
- automated planning (2)
- automated radio telemetry (2)
- automatic facial expression analysis (2)
- automatic feedback (2)
- automaticity (2)
- autonomic nervous system (2)
- autonomy support (2)
- autoregressive models (2)
- avian personalities (2)
- avirulence (2)
- axillary bud (2)
- azobenzene containing polymer films (2)
- azobenzene containing surfactants (2)
- azobenzene elastomers (2)
- azobenzene surfactant (2)
- azobenzene trimethylammonium bromide (2)
- azobenzenes (2)
- back-pain screening (2)
- background variables (2)
- bacterial O-antigen (2)
- bacterial swimming strategies (2)
- baltic sea (2)
- banal nationalism (2)
- bank filtration (2)
- bank vole (2)
- bank voles (2)
- barbell velocity (2)
- basal body (2)
- base excision repair (incision activity) (2)
- basic need satisfaction and frustration (2)
- basic psychological needs (2)
- basin analysis (2)
- basin evolution (2)
- basis-sets (2)
- batch effect (2)
- batch process (2)
- batch processing (2)
- bedload transport (2)
- behavior problems (2)
- behavioral abstraction (2)
- behavioral and self-report measures (2)
- behavioral flexibility (2)
- behavioral observation (2)
- behavioral plasticity (2)
- behavioral public administration (2)
- behavioral reasoning (2)
- behavioral type (2)
- behavioral weight loss (2)
- behavioural syndrome (2)
- benchmark (2)
- benthic food web (2)
- benzodiazepines (2)
- bet-hedging (2)
- beta diversity (2)
- beta-cell (2)
- beta-diversity (2)
- betaine (2)
- bibliometrics (2)
- bidirectional reflectance (2)
- bifurcation analysis (2)
- bifurcation theory (2)
- big data analytics (2)
- big data services (2)
- big-fish-little-pond-effect (2)
- bilingual children (2)
- bilingual infants (2)
- bilingual lexical development (2)
- bilingual processing (2)
- binary black holes (2)
- binary systems (2)
- bio-optical modeling (2)
- bioavailability (2)
- biocatalysis (2)
- biodiversity decline (2)
- biodiversity facets (2)
- bioelectrochemistry (2)
- bioenergetics (2)
- bioenergy (2)
- biofilm formation (2)
- biofilms (2)
- biogenesis (2)
- biogenic silica (2)
- bioindicators (2)
- biological control (2)
- biological invasion (2)
- biological maturation (2)
- biological pest control (2)
- biological soil crusts (2)
- biological transport (2)
- biomarker detection (2)
- biomechanical parameter (2)
- biomimetic mineralization (2)
- biomimetic recognition elements (2)
- bioprinting (2)
- biorefineries (2)
- bioremediation (2)
- biostimulant (2)
- biotechnology (2)
- biotic filtering (2)
- biotin sulfoxide reductase (2)
- birds (2)
- birefringence (2)
- birth-death-mutation-competition point process (2)
- birthweight (2)
- bisphosphonates (2)
- bistability (2)
- bitcoin (2)
- black carbon (2)
- black hole (2)
- bladder-cancer (2)
- blockchain technology (2)
- blood glucose (2)
- blood pressure (2)
- blood sample (2)
- blue stragglers (2)
- blueSeis-3A sensors (2)
- bodily self (2)
- body density (2)
- body limbs (2)
- body mass (2)
- body mass index (2)
- body proportions (2)
- body shape (2)
- body weight gain (2)
- body-mass index (2)
- body-specificity hypothesis (2)
- bone pathologies (2)
- bone tissue engineering (2)
- bone–brain–nervous system interactions (2)
- book history (2)
- bootstrapping (2)
- border (2)
- boreal forests (2)
- borehole leakage (2)
- boronic acid (2)
- bottlebrush copolymers (2)
- bottom-up fabrication (2)
- botulinum toxin (2)
- bound phenolic compounds (2)
- boundary regularity (2)
- bounded model checking (2)
- brackish waters (2)
- brain development (2)
- brain health (2)
- brain insulin signaling (2)
- branched chain amino acids (2)
- break interventions (2)
- breathing (2)
- breeding (2)
- bridge (2)
- broadband and narrowband dimensions of behavior (2)
- bromeliad (2)
- brownian-motion (2)
- browser platforms (2)
- buffer zones (2)
- bulk heterojunctions (2)
- bullying victimization (2)
- bumps (2)
- bush encroachment (2)
- business interruption (2)
- business model innovation (2)
- business process (2)
- business process modeling (2)
- business services (2)
- butyrylcholinesterase (2)
- buy recommendations (2)
- c. elegans (2)
- cGMP (2)
- cTBS (2)
- cadmium-free (2)
- calc-alkaline (2)
- calcaneal eversion (2)
- calcination (2)
- calcium carbonate inclusions (2)
- calcium influx (2)
- calcium phosphate hybrid material (2)
- callous-unemotional traits (2)
- callousness (2)
- cambridge cb4 0wf (2)
- cambs (2)
- camelid antibody (2)
- camelid heavy-chain-only antibodies (2)
- canalization (2)
- cancer chemoprevention (2)
- cancer detection (2)
- cancer epidemiology (2)
- cancer therapy (2)
- canoe racing (2)
- canonical correlations analysis (2)
- canopy height (2)
- capabilities (2)
- capacities (2)
- capacitive sensor (2)
- capstone course (2)
- capture enrichment (2)
- carbohydrate derivatives (2)
- carbohydrate interaction (2)
- carbohydrate recognition (2)
- carbohydrate‐ based (2)
- carbon budget (2)
- carbon export (2)
- carbon labeling (2)
- carbon markets (2)
- carbon materials (2)
- carbon-dioxide (2)
- carbon-dioxide capture (2)
- carbon-dioxide emissions (2)
- carbonaceous aerosols (2)
- carbonate ramp (2)
- carbonates (2)
- carboxyanhydrides (2)
- carcinogen exposure (2)
- carcinoma (2)
- cardiac catheterization (CC) (2)
- cardiac development (2)
- cardioception (2)
- cardiology (2)
- cardiomyocyte (2)
- cardiomyogenic differentiation (2)
- cardiopulmonary exercise testing (2)
- cardiovascular-disease (2)
- career plans (2)
- career success (2)
- carotenoid biosynthesis (2)
- carotenoids bioavailability (2)
- carrion ecology (2)
- carryover effects (2)
- cascade reactions (2)
- cascading effects (2)
- case (2)
- case-animacy (2)
- catalase (2)
- catalogues (2)
- catalyst (2)
- catastrophe climatique (2)
- catch-up growth (2)
- cathode (2)
- cave fish (2)
- cavity quantum electrodynamics (2)
- celestial mechanics (2)
- cell culture (2)
- cell division (2)
- cell enumeration (2)
- cell-based in vitro assay (2)
- cell-death (2)
- cellular bioimaging (2)
- cellular signaling (2)
- cellulose fibers (2)
- cellulose polymeric organic matter (2)
- cement (2)
- cement admixtures (2)
- cement hydration (2)
- cementitious material (2)
- central Mediterranean (2)
- central Mongolia (2)
- central Poland (2)
- central administration (2)
- central and peripheral vision (2)
- central fixation bias (2)
- central south island (2)
- centralization (2)
- cerami-des (2)
- ceramides (2)
- cereal leaf beetle (2)
- cereal meals (2)
- cesium lead halides (2)
- cetaceans (2)
- chains (2)
- chalcogenide (2)
- challenges (2)
- change of direction speed (2)
- change-of-direction speed (2)
- changement climatique (2)
- chaotic neural dynamics (2)
- chaperone (2)
- chaperones (2)
- charge carrier recombination (2)
- charge localisation (2)
- charge transfers (2)
- charge-carrier transport (2)
- chemical sensors (2)
- chemical-mechanical interaction (2)
- chemo-toxicity (2)
- chemoradiation therapy (2)
- chemostat experiments (2)
- chemotaxonomy (2)
- child asylum-seekers (2)
- child second language acquisition (2)
- childcare (2)
- childhood abuse (2)
- childhood obesity (2)
- chimera (2)
- chimeric transcription factors (2)
- chirality (2)
- chlorophyll (2)
- chlorophyll a (2)
- cholinesterase inhibitors (2)
- chorus waves (2)
- chromatin regulation (2)
- chromoionophore (2)
- chronic fatigue (2)
- chronic health condition (2)
- chronic low back pain (2)
- chronic psychosocial stress (2)
- chronic stress (2)
- chronic subordinate colony housing (CSC) (2)
- chronology (AICC2012) (2)
- chytridiomycota (2)
- circulation of knowledge (2)
- circulation patterns (2)
- citizen-state interactions (2)
- citric acid (2)
- civil service (2)
- class-level effects (2)
- classical conditioning (2)
- classroom (2)
- classroom characteristics (2)
- classroom climate (2)
- classroom management (2)
- clause determiner (2)
- clauses (2)
- clay (2)
- clay mineral (2)
- cleft constructions (2)
- climate catastrophe (2)
- climate change mitigation (2)
- climate drift (2)
- climate finance (2)
- climate politics (2)
- climate reconstructions (2)
- climate trends (2)
- climate varibility (2)
- climate visualization (2)
- climate-change policy (2)
- climatology (2)
- clinical (2)
- clinical pain research (2)
- clinical study (2)
- clinical supervision (2)
- clinopyroxenite (2)
- clonal complex (2)
- cloud security (2)
- cloud storage (2)
- cluster model (2)
- clusterin (2)
- clusters (2)
- co-creation (2)
- co-expression (2)
- co-ordination (2)
- coagulation (2)
- coarea formula (2)
- coast (2)
- coastal flood damage (2)
- coastal flooding (2)
- coastal geomorphology (2)
- coat colour (2)
- cobalt nanoparticles (2)
- cockroach salivary-glands (2)
- codifference (2)
- coefficients (2)
- coenzyme-a (2)
- coesite (2)
- coffee (2)
- cognitive (2)
- cognitive interference (2)
- cognitive linguistics (2)
- cognitive load (2)
- cognitive resources (2)
- cognitive science (2)
- cognitive training (2)
- cognitive-behavioral control (2)
- cognitive-behavioural therapy (2)
- cognitive-behavioural therapy (CBT) (2)
- cognitive-control (2)
- cognitive/muscular fatigue (2)
- coherent noise (2)
- coherent phonons (2)
- cohomology (2)
- cold stress (2)
- collaborative learning (2)
- collaborative work (2)
- collection types (2)
- collective motion (2)
- college students (2)
- collision (2)
- colloid (2)
- colonial Australia (2)
- colony decline (2)
- colony viability (2)
- coloring agents (2)
- combined task and motion planning (2)
- commemorative acts of citizenship (2)
- commitment (2)
- common ground (2)
- common‐garden experiment (2)
- community model (2)
- community theory (2)
- comorbidities (2)
- comparative (2)
- comparative subclause (2)
- comparative subclauses (2)
- comparison of devices (2)
- competencies (2)
- competition–defense trade‐off (2)
- competitive inhibition (2)
- complaints (2)
- complex network (2)
- complex predicates (2)
- complex problems (2)
- complex sentence processing (2)
- complex words (2)
- composite material (2)
- composite materials (2)
- composite properties (2)
- compound (2)
- compound flood (2)
- compounds (2)
- comprehensive analysis (2)
- compression (2)
- computational morphodynamics (2)
- computer graphics (2)
- computer science (2)
- computer-mediated therapy (2)
- concentrated solar power (2)
- concentrating solar power (2)
- concentration (2)
- concurrent checking (2)
- conditional reasoning (2)
- conditioning activity (2)
- conditioning exercise (2)
- conduct disorder (2)
- confidence (2)
- confidence intervals (2)
- confidence sets (2)
- conflict (2)
- conflict management (2)
- conflict monitoring (2)
- confocal Raman microscopy (2)
- conformance checking (2)
- conformational change (2)
- conformational rearrangement (2)
- conformational-changes (2)
- confusion (2)
- congruity effect (2)
- conjugate gradient (2)
- connections between chaos and statistical physics (2)
- conscientiousness (2)
- conservation biology (2)
- conservation laws (2)
- conservation planning (2)
- conservation targets (2)
- consonant bias (2)
- constitutive activity (2)
- constraint (2)
- consultation (2)
- consumer diversity (2)
- consumer education (2)
- consumer empowerment (2)
- content (2)
- content knowledge (2)
- contentious politics (2)
- context sensitivity (2)
- continental collision (2)
- continental rifting (2)
- continuing education activities (2)
- continuous glucose monitoring (2)
- continuous integration (2)
- continuous process (2)
- continuous simulation (2)
- continuous testing (2)
- continuous time random walk (CTRW) (2)
- continuous-time data assimilation (2)
- contractions (2)
- contrast effect (2)
- contrast effects (2)
- control rates (2)
- controlled polymerization (2)
- controlled trial (2)
- convective available potential energy (2)
- convective available potential energy (CAPE) (2)
- conversational implicature (2)
- conversion (2)
- converting factor (2)
- convolutional neural networks (2)
- cooperating systems (2)
- cooperative goal interdependence (2)
- cooperative phenomena (2)
- copolymerization (2)
- copper complex (2)
- copper-bearing minerals (2)
- copper-related disorders (2)
- copy number analyses (2)
- cord blood (2)
- core PG1351 (2)
- core shell UCNP (2)
- core strength (2)
- core-shell materials (2)
- core-shell nanostructure (2)
- coregistration (2)
- cori cycle (2)
- corona (2)
- coronary heart disease (2)
- corporate citizenship (2)
- corporate foresight (2)
- corporate leniency program (2)
- corporate social responsibility (2)
- corporeality (2)
- corpus dataset (2)
- cortical network models (2)
- cortical oscillations (2)
- cosmic background radiation (2)
- cosmic ray propagation (2)
- cosmogenic radionuclides (2)
- cosmological simulations (2)
- cosmopolitanism and nationalism (2)
- cost-effectiveness (2)
- coumarins (2)
- counter-speech (2)
- counterterms (2)
- country (2)
- coupled oscillators model (2)
- coupled surface (2)
- coupling (2)
- coupling methods (2)
- course design (2)
- course timetabling (2)
- coviability analysis (2)
- cow's milk (2)
- craving and relapse (2)
- creative problem solving (2)
- creative process (2)
- criminology (2)
- crisis communication (2)
- criterial (2)
- critical fluctuations (2)
- critical meteorological condition (2)
- critical solution temperature (2)
- crop diversity (2)
- cropping system (2)
- cross-cultural differences (2)
- cross-education (2)
- cross-linguistic differences (2)
- cross-linking (2)
- cross-modal generalisation (2)
- cross-modal priming (2)
- cross-national comparison (2)
- cross-species capture (2)
- crowded fluids (2)
- crowdsourcing (2)
- cruciate ligament injury (2)
- crustacean zooplankton (2)
- crustal thickness (2)
- cryo-electron microscopy (2)
- cryogel (2)
- cryptic species complex (2)
- cryptomycota (2)
- crystal orientation (2)
- crystal structures (2)
- crystallinity (2)
- crystallization behavior (2)
- crystals (2)
- cues (2)
- culling of male chickens (2)
- cultural conceptualisations (2)
- cultural heritage (2)
- cultural minority youth (2)
- customer acceptance (2)
- cyanobacterial bloom (2)
- cyanobacterial sucrose-phosphatase (2)
- cyber-physische Systeme (2)
- cyberaggression (2)
- cybersecurity (2)
- cycle (2)
- cyclic AMP (2)
- cycling (2)
- cyclooxygenase (2)
- cysteine alkylation (2)
- cytochrome P450 17A1 (Cyp17A1) (2)
- cytoplasm (2)
- cytoplasmic polyadenylation (2)
- cytotype (2)
- dark virus (2)
- data cleaning (2)
- data pipeline (2)
- data privacy (2)
- data protection (2)
- data scarcity (2)
- data sharing (2)
- data synthesis (2)
- data-driven (2)
- data-mining (2)
- database systems (2)
- ddRAD (2)
- de Rham complex (2)
- de novo genome assembly (2)
- de-concentration (2)
- dead Cas9 (2)
- debris flows (2)
- debt (2)
- debugging (2)
- decentralisation (2)
- decision processes (2)
- decision trees (2)
- decision-theory (2)
- decline (2)
- decomposition analysis (2)
- decomposition methods (2)
- deep carbon cycle (2)
- deep reinforcement learning (2)
- defensive symbiosis (2)
- deferred choice (2)
- deficiency (2)
- definiteness (2)
- deformation monitoring (2)
- degradable polymer (2)
- degradable polymers (2)
- dehydroepiandrosterone sulfate (2)
- delayed onset muscle soreness (2)
- delta-c-13 (2)
- democratic quality (2)
- democratic theory (2)
- democratization (2)
- demographic change (2)
- demographic noise (2)
- dendrimers (2)
- dendritic cell (2)
- dendrometer measurements (2)
- density dependence (2)
- density-driven flow (2)
- dentistry (2)
- dependence (2)
- dependency (2)
- dependency discovery (2)
- dependency resolution (2)
- depressive-like behavior (2)
- derivational affixes (2)
- derivational complexity (2)
- derivational morphology (2)
- desert (2)
- desiccation (2)
- design of experiment (2)
- design options (2)
- detection (2)
- detector development (2)
- determinants of plant community diversity and structure (2)
- determiners (2)
- detrital carbonate (2)
- deuterium (2)
- developing brain (2)
- development cooperation (2)
- development of minimal self (2)
- developmental canalization (2)
- developmental dyslexia (2)
- developmental language impairment (2)
- developmental plasticity (2)
- developmental trajectories (2)
- dew-point temperature (2)
- diabetes mellitus (2)
- diabetic (2)
- diachrony (2)
- diacylglycerol (2)
- diagnosis (2)
- diagnostic techniques and procedures (2)
- diagnostics (2)
- dialect (2)
- dialysis (2)
- diary study (2)
- diaspora (2)
- diazo compounds (2)
- dichotic listening (2)
- dictyostelium (2)
- dielectric (2)
- dielectric barrier discharge (DBD) (2)
- dielectric barrier discharges (2)
- dielectric properties (2)
- dielectric spectroscopy (2)
- dielectrics (2)
- dienes (2)
- dietary fibre (2)
- dietary intake (2)
- dietary quality (2)
- dietary restriction (2)
- difference operator (2)
- difference-in-difference (2)
- differential expression analysis (2)
- differential split-sample test (2)
- digestive enzymes quantification (2)
- digging-in effects (2)
- digital bathymetric model (2)
- digital elevation model (DEM) (2)
- digital identity (2)
- digital interventions (2)
- digital media (2)
- digitale Souveränität (2)
- digitalisation (2)
- digitization (2)
- diimine-complexes (2)
- dimension independent bound (2)
- dimensional (2)
- dimensional comparison (2)
- dimensional stability (2)
- dimerization (2)
- dimerization of 4-nitrothiophenol (2)
- dip-coating (2)
- direct effects (2)
- direct manipulation (2)
- discharge (2)
- discipline differences (2)
- discounting (2)
- discourse comprehension (2)
- discrimination networks (2)
- disease ecology (2)
- disease severity (2)
- diselenide (2)
- disorder recognition (2)
- disorders (2)
- dispersal filtering (2)
- displacement (2)
- dissociation kinetics (2)
- dissolution (2)
- distance scale (2)
- distributed processing (2)
- distributions (2)
- disulfide (2)
- ditch irrigation (2)
- divergence (2)
- diversity climate (2)
- diversity profiles (2)
- division of labor (2)
- division of labour (2)
- division of spaces (2)
- divorce (2)
- dna coiling (2)
- dominance effect (2)
- dominance effects (2)
- donor (2)
- donor-acceptor systems (2)
- dormancy (2)
- drained lake basins (2)
- driven (2)
- driving force (2)
- drought events (2)
- drought index (2)
- drought tolerance (2)
- drug control (2)
- drug instrumentalization (2)
- drug metabolism (2)
- drug monitoring (2)
- drug release (2)
- drug-sensitivity prediction (2)
- dry and mesic grasslands (2)
- dual GLP-1/glucagon receptor agonist (2)
- dual task (2)
- dual-process models (2)
- dual-task (2)
- dual-task costs (2)
- duality formula (2)
- dunkle Materie (2)
- dust sources (2)
- dwarfs galaxies (2)
- dye adsorption (2)
- dye mixture (2)
- dyes/pigments (2)
- dynamic HPLC (2)
Institute
- Institut für Physik und Astronomie (4734)
- Institut für Biochemie und Biologie (4564)
- Institut für Geowissenschaften (3172)
- Institut für Chemie (2804)
- Institut für Mathematik (1544)
- Department Psychologie (1364)
- Institut für Ernährungswissenschaft (990)
- Department Linguistik (896)
- Wirtschaftswissenschaften (818)
- Institut für Informatik und Computational Science (787)
Research on novel and advanced biomaterials is an indispensable step towards their applications in desirable fields such as tissue engineering, regenerative medicine, cell culture, or biotechnology. The work presented here focuses on such a promising material: polyelectrolyte multilayer (PEM) composed of hyaluronic acid (HA) and poly(L-lysine) (PLL). This gel-like polymer surface coating is able to accumulate (bio-)molecules such as proteins or drugs and release them in a controlled manner. It serves as a mimic of the extracellular matrix (ECM) in composition and intrinsic properties. These qualities make the HA/PLL multilayers a promising candidate for multiple bio-applications such as those mentioned above. The work presented aims at the development of a straightforward approach for assessment of multi-fractional diffusion in multilayers (first part) and at control of local molecular transport into or from the multilayers by laser light trigger (second part).
The mechanism of the loading and release is governed by the interaction of bioactives with the multilayer constituents and by the diffusion phenomenon overall. The diffusion of a molecule in HA/PLL multilayers shows multiple fractions of different diffusion rate. Approaches, that are able to assess the mobility of molecules in such a complex system, are limited. This shortcoming motivated the design of a novel evaluation tool presented here.
The tool employs a simulation-based approach for evaluation of the data acquired by fluorescence recovery after photobleaching (FRAP) method. In this approach, possible fluorescence recovery scenarios are primarily simulated and afterwards compared with the data acquired while optimizing parameters of a model until a sufficient match is achieved. Fluorescent latex particles of different sizes and fluorescein in an aqueous medium are utilized as test samples validating the analysis results. The diffusion of protein cytochrome c in HA/PLL multilayers is evaluated as well.
This tool significantly broadens the possibilities of analysis of spatiotemporal FRAP data, which originate from multi-fractional diffusion, while striving to be widely applicable. This tool has the potential to elucidate the mechanisms of molecular transport and empower rational engineering of the drug release systems.
The second part of the work focuses on the fabrication of such a spatiotemporarily-controlled drug release system employing the HA/PLL multilayer. This release system comprises different layers of various functionalities that together form a sandwich structure. The bottom layer, which serves as a reservoir, is formed by HA/PLL PEM deposited on a planar glass substrate. On top of the PEM, a layer of so-called hybrids is deposited. The hybrids consist of thermoresponsive poly(N-isopropylacrylamide) (PNIPAM) -based hydrogel microparticles with surface-attached gold nanorods. The layer of hybrids is intended to serve as a gate that controls the local molecular transport through the PEM–solution-interface. The possibility of stimulating the molecular transport by near-infrared (NIR) laser irradiation is being explored.
From several tested approaches for the deposition of hybrids onto the PEM surface, the drying-based approach was identified as optimal. Experiments, that examine the functionality of the fabricated sandwich at elevated temperature, document the reversible volume phase transition of the PEM-attached hybrids while sustaining the sandwich stability. Further, the gold nanorods were shown to effectively absorb light radiation in the tissue- and cell-friendly NIR spectral region while transducing the energy of light into heat. The rapid and reversible shrinkage of the PEM-attached hybrids was thereby achieved. Finally, dextran was employed as a model transport molecule. It loads into the PEM reservoir in a few seconds with the partition constant of 2.4, while it spontaneously releases in a slower, sustained manner. The local laser irradiation of the sandwich, which contains the fluorescein isothiocyanate tagged dextran, leads to a gradual reduction of fluorescence intensity in the irradiated region.
The release system fabricated employs renowned photoresponsivity of the hybrids in an innovative setting. The results of the research are a step towards a spatially-controlled on-demand drug release system that paves the way to spatiotemporally controlled drug release.
The approaches developed in this work have the potential to elucidate the molecular dynamics in ECM and to foster engineering of multilayers with properties tuned to mimic the ECM. The work aims at spatiotemporal control over the diffusion of bioactives and their presentation to the cells.
The large literature that aims to find evidence of climate migration delivers mixed findings. This meta-regression analysis i) summarizes direct links between adverse climatic events and migration, ii) maps patterns of climate migration, and iii) explains the variation in outcomes. Using a set of limited dependent variable models, we meta-analyze thus-far the most comprehensive sample of 3,625 estimates from 116 original studies and produce novel insights on climate migration. We find that extremely high temperatures and drying conditions increase migration. We do not find a significant effect of sudden-onset events. Climate migration is most likely to emerge due to contemporaneous events, to originate in rural areas and to take place in middle-income countries, internally, to cities. The likelihood to become trapped in affected areas is higher for women and in low-income countries, particularly in Africa. We uniquely quantify how pitfalls typical for the broader empirical climate impact literature affect climate migration findings. We also find evidence of different publication biases.
In this paper, we move from the large strand of research that looks at evidence of climate migration to the questions: who are the climate migrants? and where do they go? These questions are crucial to design policies that mitigate welfare losses of migration choices due to climate change. We study the direct and heterogeneous associations between weather extremes and migration in rural India. We combine ERAS reanalysis data with the India Human Development Survey household panel and conduct regression analyses by applying linear probability and multinomial logit models. This enables us to establish a causal relationship between temperature and precipitation anomalies and overall migration as well as migration by destination. We show that adverse weather shocks decrease rural-rural and international migration and push people into cities in different, presumably more prosperous states. A series of positive weather shocks, however, facilitates international migration and migration to cities within the same state. Further, our results indicate that in contrast to other migrants, climate migrants are likely to be from the lower end of the skill distribution and from households strongly dependent on agricultural production. We estimate that approximately 8% of all rural-urban moves between 2005 and 2012 can be attributed to weather. This figure might increase as a consequence of climate change. Thus, a key policy recommendation is to take steps to facilitate integration of less educated migrants into the urban labor market.
While estimated numbers of past and future climate migrants are alarming, the growing empirical evidence suggests that the association between adverse climate-related events and migration is not universally positive. This dissertation seeks to advance our understanding of when and how climate migration emerges by analyzing heterogeneous climatic influences on migration in low- and middle-income countries. To this end, it draws on established economic theories of migration, datasets from physical and social sciences, causal inference techniques and approaches from systematic literature review. In three of its five chapters, I estimate causal effects of processes of climate change on inequality and migration in India and Sub-Saharan Africa. By employing interaction terms and by analyzing sub-samples of data, I explore how these relationships differ for various segments of the population. In the remaining two chapters, I present two systematic literature reviews. First, I undertake a comprehensive meta-regression analysis of the econometric climate migration literature to summarize general climate migration patterns and explain the conflicting findings. Second, motivated by the broad range of approaches in the field, I examine the literature from a methodological perspective to provide best practice guidelines for studying climate migration empirically. Overall, the evidence from this dissertation shows that climatic influences on human migration are highly heterogeneous. Whether adverse climate-related impacts materialize in migration depends on the socio-economic characteristics of the individual households, such as wealth, level of education, agricultural dependence or access to adaptation technologies and insurance. For instance, I show that while adverse climatic shocks are generally associated with an increase in migration in rural India, they reduce migration in the agricultural context of Sub-Saharan Africa, where the average wealth levels are much lower so that households largely cannot afford the upfront costs of moving. I find that unlike local climatic shocks which primarily enhance internal migration to cities and hence accelerate urbanization, shocks transmitted via agricultural producer prices increase migration to neighboring countries, likely due to the simultaneous decrease in real income in nearby urban areas. These findings advance our current understanding by showing when and how economic agents respond to climatic events, thus providing explicit contexts and mechanisms of climate change effects on migration in the future. The resulting collection of findings can guide policy interventions to avoid or mitigate any present and future welfare losses from climate change-related migration choices.
We show that the codifference is a useful tool in studying the ergodicity breaking and non-Gaussianity properties of stochastic time series. While the codifference is a measure of dependence that was previously studied mainly in the context of stable processes, we here extend its range of applicability to random-parameter and diffusing-diffusivity models which are important in contemporary physics, biology and financial engineering. We prove that the codifference detects forms of dependence and ergodicity breaking which are not visible from analysing the covariance and correlation functions. We also discuss a related measure of dispersion, which is a nonlinear analogue of the mean squared displacement.
Recent advances in single particle tracking and supercomputing techniques demonstrate the emergence of normal or anomalous, viscoelastic diffusion in conjunction with non-Gaussian distributions in soft, biological, and active matter systems. We here formulate a stochastic model based on a generalised Langevin equation in which non-Gaussian shapes of the probability density function and normal or anomalous diffusion have a common origin, namely a random parametrisation of the stochastic force. We perform a detailed analysis demonstrating how various types of parameter distributions for the memory kernel result in exponential, power law, or power-log law tails of the memory functions. The studied system is also shown to exhibit a further unusual property: the velocity has a Gaussian one point probability density but non-Gaussian joint distributions. This behaviour is reflected in the relaxation from a Gaussian to a non-Gaussian distribution observed for the position variable. We show that our theoretical results are in excellent agreement with stochastic simulations.
Recent advances in single particle tracking and supercomputing techniques demonstrate the emergence of normal or anomalous, viscoelastic diffusion in conjunction with non-Gaussian distributions in soft, biological, and active matter systems. We here formulate a stochastic model based on a generalised Langevin equation in which non-Gaussian shapes of the probability density function and normal or anomalous diffusion have a common origin, namely a random parametrisation of the stochastic force. We perform a detailed analysis demonstrating how various types of parameter distributions for the memory kernel result in exponential, power law, or power-log law tails of the memory functions. The studied system is also shown to exhibit a further unusual property: the velocity has a Gaussian one point probability density but non-Gaussian joint distributions. This behaviour is reflected in the relaxation from a Gaussian to a non-Gaussian distribution observed for the position variable. We show that our theoretical results are in excellent agreement with stochastic simulations.
We show that the codifference is a useful tool in studying the ergodicity breaking and non-Gaussianity properties of stochastic time series. While the codifference is a measure of dependence that was previously studied mainly in the context of stable processes, we here extend its range of applicability to random-parameter and diffusing-diffusivity models which are important in contemporary physics, biology and financial engineering. We prove that the codifference detects forms of dependence and ergodicity breaking which are not visible from analysing the covariance and correlation functions. We also discuss a related measure of dispersion, which is a nonlinear analogue of the mean squared displacement.
Many studies on biological and soft matter systems report the joint presence of a linear mean-squared displacement and a non-Gaussian probability density exhibiting, for instance, exponential or stretched-Gaussian tails. This phenomenon is ascribed to the heterogeneity of the medium and is captured by random parameter models such as ‘superstatistics’ or ‘diffusing diffusivity’. Independently, scientists working in the area of time series analysis and statistics have studied a class of discrete-time processes with similar properties, namely, random coefficient autoregressive models. In this work we try to reconcile these two approaches and thus provide a bridge between physical stochastic processes and autoregressive models.Westart from the basic Langevin equation of motion with time-varying damping or diffusion coefficients and establish the link to random coefficient autoregressive processes. By exploring that link we gain access to efficient statistical methods which can help to identify data exhibiting Brownian yet non-Gaussian diffusion.
Many studies on biological and soft matter systems report the joint presence of a linear mean-squared displacement and a non-Gaussian probability density exhibiting, for instance, exponential or stretched-Gaussian tails. This phenomenon is ascribed to the heterogeneity of the medium and is captured by random parameter models such as ‘superstatistics’ or ‘diffusing diffusivity’. Independently, scientists working in the area of time series analysis and statistics have studied a class of discrete-time processes with similar properties, namely, random coefficient autoregressive models. In this work we try to reconcile these two approaches and thus provide a bridge between physical stochastic processes and autoregressive models.Westart from the basic Langevin equation of motion with time-varying damping or diffusion coefficients and establish the link to random coefficient autoregressive processes. By exploring that link we gain access to efficient statistical methods which can help to identify data exhibiting Brownian yet non-Gaussian diffusion.
Background:
Plant phenotypic data shrouds a wealth of information which, when accurately analysed and linked
to other data types, brings to light the knowledge about the mechanisms of life. As phenotyping is a field of research
comprising manifold, diverse and time
‑consuming experiments, the findings can be fostered by reusing and combin‑
ing existing datasets. Their correct interpretation, and thus replicability, comparability and interoperability, is possible
provided that the collected observations are equipped with an adequate set of metadata. So far there have been no
common standards governing phenotypic data description, which hampered data exchange and reuse.
Results:
In this paper we propose the guidelines for proper handling of the information about plant phenotyping
experiments, in terms of both the recommended content of the description and its formatting. We provide a docu‑
ment called “Minimum Information About a Plant Phenotyping Experiment”, which specifies what information about
each experiment should be given, and a Phenotyping Configuration for the ISA
‑Tab format, which allows to practically
organise this information within a dataset. We provide examples of ISA
‑Tab
‑formatted phenotypic data, and a general
description of a few systems where the recommendations have been implemented.
Conclusions:
Acceptance of the rules described in this paper by the plant phenotyping community will help to
achieve findable, accessible, interoperable and reusable data.
The Proteasome Acts as a Hub for Plant Immunity and Is Targeted by Pseudomonas Type III Effectors
(2016)
Recent evidence suggests that the ubiquitin-proteasome system is involved in several aspects of plant immunity and that a range of plant pathogens subvert the ubiquitin-proteasome system to enhance their virulence. Here, we show that proteasome activity is strongly induced during basal defense in Arabidopsis (Arabidopsis thaliana). Mutant lines of the proteasome subunits RPT2a and RPN12a support increased bacterial growth of virulent Pseudomonas syringae pv tomato DC3000 (Pst) and Pseudomonas syringae pv maculicola ES4326. Both proteasome subunits are required for pathogen-associated molecular pattern-triggered immunity responses. Analysis of bacterial growth after a secondary infection of systemic leaves revealed that the establishment of systemic acquired resistance (SAR) is impaired in proteasome mutants, suggesting that the proteasome also plays an important role in defense priming and SAR. In addition, we show that Pst inhibits proteasome activity in a type III secretion-dependent manner. A screen for type III effector proteins from Pst for their ability to interfere with proteasome activity revealed HopM1, HopAO1, HopA1, and HopG1 as putative proteasome inhibitors. Biochemical characterization of HopM1 by mass spectrometry indicates that HopM1 interacts with several E3 ubiquitin ligases and proteasome subunits. This supports the hypothesis that HopM1 associates with the proteasome, leading to its inhibition. Thus, the proteasome is an essential component of pathogen-associated molecular pattern-triggered immunity and SAR, which is targeted by multiple bacterial effectors.
XopJ is a Xanthomonas type III effector protein that promotes bacterial virulence on susceptible pepper plants through the inhibition of the host cell proteasome and a resultant suppression of salicylic acid (SA) - dependent defense responses. We show here that Nicotiana benthamiana leaves transiently expressing XopJ display hypersensitive response (HR) -like symptoms when exogenously treated with SA. This apparent avirulence function of XopJ was further dependent on effector myristoylation as well as on an intact catalytic triad, suggesting a requirement of its enzymatic activity for HR-like symptom elicitation. The ability of XopJ to cause a HR-like symptom development upon SA treatment was lost upon silencing of SGT1 and NDR1, respectively, but was independent of EDS1 silencing, suggesting that XopJ is recognized by an R protein of the CC-NBS-LRR class. Furthermore, silencing of NPR1 abolished the elicitation of HR-like symptoms in XopJ expressing leaves after SA application. Measurement of the proteasome activity indicated that proteasome inhibition by XopJ was alleviated in the presence of SA, an effect that was not observed in NPR1 silenced plants. Our results suggest that XopJ - triggered HR-like symptoms are closely related to the virulence function of the effector and that XopJ follows a two-signal model in order to elicit a response in the non-host plant N. benthamiana.
XopJ is a Xanthomonas type III effector protein that promotes bacterial virulence on susceptible pepper plants through the inhibition of the host cell proteasome and a resultant suppression of salicylic acid (SA) - dependent defense responses. We show here that Nicotiana benthamiana leaves transiently expressing XopJ display hypersensitive response (HR) -like symptoms when exogenously treated with SA. This apparent avirulence function of XopJ was further dependent on effector myristoylation as well as on an intact catalytic triad, suggesting a requirement of its enzymatic activity for HR-like symptom elicitation. The ability of XopJ to cause a HR-like symptom development upon SA treatment was lost upon silencing of SGT1 and NDR1, respectively, but was independent of EDS1 silencing, suggesting that XopJ is recognized by an R protein of the CC-NBS-LRR class. Furthermore, silencing of NPR1 abolished the elicitation of HR-like symptoms in XopJ expressing leaves after SA application. Measurement of the proteasome activity indicated that proteasome inhibition by XopJ was alleviated in the presence of SA, an effect that was not observed in NPR1 silenced plants. Our results suggest that XopJ - triggered HR-like symptoms are closely related to the virulence function of the effector and that XopJ follows a two-signal model in order to elicit a response in the non-host plant N. benthamiana.
Quantitative estimates of sea-level rise in the Mediterranean Basin become increasingly accurate thanks to detailed satellite monitoring. However, such measuring campaigns cover several years to decades, while longer-term sea-level records are rare for the Mediterranean. We used a data archeological approach to reanalyze monthly mean sea-level data of the Antalya-I (1935–1977) tide gauge to fill this gap. We checked the accuracy and reliability of these data before merging them with the more recent records of the Antalya-II (1985–2009) tide gauge, accounting for an eight-year hiatus. We obtain a composite time series of monthly and annual mean sea levels spanning some 75 years, providing the longest record for the eastern Mediterranean Basin, and thus an essential tool for studying the region's recent sea-level trends. We estimate a relative mean sea-level rise of 2.2 ± 0.5 mm/year between 1935 and 2008, with an annual variability (expressed here as the standard deviation of the residuals, σresiduals = 41.4 mm) above that at the closest tide gauges (e.g., Thessaloniki, Greece, σresiduals = 29.0 mm). Relative sea-level rise accelerated to 6.0 ± 1.5 mm/year at Antalya-II; we attribute roughly half of this rate (~3.6 mm/year) to tectonic crustal motion and anthropogenic land subsidence. Our study highlights the value of data archeology for recovering and integrating historic tide gauge data for long-term sea-level and climate studies.
Landslides are frequent natural hazards in rugged terrain, when the resisting frictional force of the surface of rupture yields to the gravitational force. These forces are functions of geological and morphological factors, such as angle of internal friction, local slope gradient or curvature, which remain static over hundreds of years; whereas more dynamic triggering events, such as rainfall and earthquakes, compromise the force balance by temporarily reducing resisting forces or adding transient loads. This thesis investigates landslide distribution and orientation due to landslide triggers (e.g. rainfall) at different scales (6-4∙10^5 km^2) and aims to link rainfall movement with the landslide distribution. It additionally explores the local impacts of the extreme rainstorms on landsliding and the role of precursory stability conditions that could be induced by an earlier trigger, such as an earthquake.
Extreme rainfall is a common landslide trigger. Although several studies assessed rainfall intensity and duration to study the distribution of thus triggered landslides, only a few case studies quantified spatial rainfall patterns (i.e. orographic effect). Quantifying the regional trajectories of extreme rainfall could aid predicting landslide prone regions in Japan. To this end, I combined a non-linear correlation metric, namely event synchronization, and radial statistics to assess the general pattern of extreme rainfall tracks over distances of hundreds of kilometers using satellite based rainfall estimates. Results showed that, although the increase in rainfall intensity and duration positively correlates with landslide occurrence, the trajectories of typhoons and frontal storms were insufficient to explain landslide distribution in Japan. Extreme rainfall trajectories inclined northwestwards and were concentrated along some certain locations, such as coastlines of southern Japan, which was unnoticed in the landslide distribution of about 5000 rainfall-triggered landslides. These landslides seemed to respond to the mean annual rainfall rates.
Above mentioned findings suggest further investigation on a more local scale to better understand the mechanistic response of landscape to extreme rainfall in terms of landslides. On May 2016 intense rainfall struck southern Germany triggering high waters and landslides. The highest damage was reported at the Braunsbach, which is located on the tributary-mouth fan formed by the Orlacher Bach. Orlacher Bach is a ~3 km long creek that drains a catchment of about ~6 km^2. I visited this catchment in June 2016 and mapped 48 landslides along the creek. Such high landslide activity was not reported in the nearby catchments within ~3300 km^2, despite similar rainfall intensity and duration based on weather radar estimates. My hypothesis was that several landslides were triggered by rainfall-triggered flash floods that undercut hillslope toes along the Orlacher Bach. I found that morphometric features such as slope and curvature play an important role in landslide distribution on this micro scale study site (<10 km^2). In addition, the high number of landslides along the Orlacher Bach could also be boosted by accumulated damages on hillslopes due karst weathering over longer time scales.
Precursory damages on hillslopes could also be induced by past triggering events that effect landscape evolution, but this interaction is hard to assess independently from the latest trigger. For example, an earthquake might influence the evolution of a landscape decades long, besides its direct impacts, such as landslides that follow the earthquake. Here I studied the consequences of the 2016 Kumamoto Earthquake (MW 7.1) that triggered some 1500 landslides in an area of ~4000 km^2 in central Kyushu, Japan. Topography, i.e. local slope and curvature, both amplified and attenuated seismic waves, thus controlling the failure mechanism of those landslides (e.g. progressive). I found that topography fails in explaining the distribution and the preferred orientation of the landslides after the earthquake; instead the landslides were concentrated around the northeast of the rupture area and faced mostly normal to the rupture plane. This preferred location of the landslides was dominated mainly by the directivity effect of the strike-slip earthquake, which is the propagation of wave energy along the fault in the rupture direction; whereas amplitude variations of the seismic radiation altered the preferred orientation. I suspect that the earthquake directivity and the asymmetry of seismic radiation damaged hillslopes at those preferred locations increasing landslide susceptibility. Hence a future weak triggering event, e.g. scattered rainfall, could further trigger landslides at those damaged hillslopes.
Reading requires the assembly of cognitive processes across a wide spectrum from low-level visual perception to high-level discourse comprehension. One approach of unravelling the dynamics associated with these processes is to determine how eye movements are influenced by the characteristics of the text, in particular which features of the words within the perceptual span maximise the information intake due to foveal, spillover, parafoveal, and predictive processing. One way to test the generalisability of current proposals of such distributed processing is to examine them across different languages. For Turkish, an agglutinative language with a shallow orthography-phonology mapping, we replicate the well-known canonical main effects of frequency and predictability of the fixated word as well as effects of incoming saccade amplitude and fixation location within the word on single-fixation durations with data from 35 adults reading 120 nine-word sentences. Evidence for previously reported effects of the characteristics of neighbouring words and interactions was mixed. There was no evidence for the expected Turkish-specific morphological effect of the number of inflectional suffixes on single-fixation durations. To control for word-selection bias associated with single-fixation durations, we also tested effects on word skipping, single-fixation, and multiple-fixation cases with a base-line category logit model, assuming an increase of difficulty for an increase in the number of fixations. With this model, significant effects of word characteristics and number of inflectional suffixes of foveal word on probabilities of the number of fixations were observed, while the effects of the characteristics of neighbouring words and interactions were mixed.
Because of political conflicts and climate change, migration will be increased worldwide and integration in host societies is a challenge also for migrants. We hypothesize that migrants, who take up the challenge in a new social environment are taller than migrants who do not pose this challenge. We analyze by a questionnaire possible social, nutritional and ethnic influencing factors to body height (BH) of adult offspring of Turkish migrants (n = 82, 39 males) aged from 18 to 34 years (mean age 24.6 years). The results of multiple regression (downward selection) show that the more a male adult offspring of Turkish migrants feels like belonging to the Turkish culture, the smaller he is (95% CI, -3.79, -0.323). Further, the more a male adult offspring of Turkish migrants feels like belonging to the German culture, the taller he is (95% CI, -0.152, 1.738). We discussed it comparable to primates taking up their challenge in dominance, where as a result their body size increase is associated with higher IGF-1 level. IGF-1 is associated with emotional belonging and has a fundamental role in the regulation of metabolism and growth of the human body. With all pilot characteristics of our study results show that the successful challenge of integration in a new society is strongly associated with the emotional integration and identification in the sense of a personal sense of belonging to society. We discuss taller BH as a signal of social growth adjustment. In this sense, a secular trend of BH adaptation of migrants to hosts is a sign of integration.
In this study, the spatial and temporal impacts of the Ataturk Dam on agro-meteorological aspects of the Southeastern Anatolia region have been investigated. Change detection and environmental impacts due to water-reserve changes in Ataturk Dam Lake have been determined and evaluated using multi-temporal Landsat satellite imageries and meteorological datasets within a period of 1984-2011. These time series have been evaluated for three time periods. Dam construction period constitutes the first part of the study. Land cover/use changes especially on agricultural fields under the Ataturk Dam Lake and its vicinity have been identified between the periods of 1984-1992. The second period comprises the 10-year period after the completion of filling up the reservoir in 1992. At this period, Landsat and meteorological time-series analyses are examined to assess the impact of the Ataturk Dam Lake on selected irrigated agricultural areas. For the last 9-year period from 2002 to 2011, the relationships between seasonal water-reserve changes and irrigated plains under changing climatic factors primarily driving vegetation activity (monthly, seasonal, and annual fluctuations of rainfall rate, air temperature, humidity) on the watershed have been investigated using a 30-year meteorological time series. The results showed that approximately 368 km(2) of agricultural fields have been affected because of inundation due to the Ataturk Dam Lake. However, irrigated agricultural fields have been increased by 56.3% of the total area (1552 of 2756 km(2)) on Harran Plain within the period of 1984-2011.
We present the fabrication of TiO2 nanotube electrodes with high biocompatibility and extraordinary spectroscopic properties. Intense surface-enhanced resonance Raman signals of the heme unit of the redox enzyme Cytochromeb(5) were observed upon covalent immobilization of the protein matrix on the TiO2 surface, revealing overall preserved structural integrity and redox behavior. The enhancement factor could be rationally controlled by varying the electrode annealing temperature, reaching a record maximum value of over 70 at 475 degrees C. For the first time, such high values are reported for non-directly surface-interacting probes, for which the involvement of charge-transfer processes in signal amplification can be excluded. The origin of the surface enhancement is exclusively attributed to enhanced localized electric fields resulting from the specific optical properties of the nanotubular geometry of the electrode.
The Sun is a star, which due to its proximity has a tremendous influence on Earth. Since its very first days mankind tried to "understand the Sun", and especially in the 20th century science has uncovered many of the Sun's secrets by using high resolution observations and describing the Sun by means of models. As an active star the Sun's activity, as expressed in its magnetic cycle, is closely related to the sunspot numbers. Flares play a special role, because they release large energies on very short time scales. They are correlated with enhanced electromagnetic emissions all over the spectrum. Furthermore, flares are sources of energetic particles. Hard X-ray observations (e.g., by NASA's RHESSI spacecraft) reveal that a large fraction of the energy released during a flare is transferred into the kinetic energy of electrons. However the mechanism that accelerates a large number of electrons to high energies (beyond 20 keV) within fractions of a second is not understood yet. The thesis at hand presents a model for the generation of energetic electrons during flares that explains the electron acceleration based on real parameters obtained by real ground and space based observations. According to this model photospheric plasma flows build up electric potentials in the active regions in the photosphere. Usually these electric potentials are associated with electric currents closed within the photosphere. However as a result of magnetic reconnection, a magnetic connection between the regions of different magnetic polarity on the photosphere can establish through the corona. Due to the significantly higher electric conductivity in the corona, the photospheric electric power supply can be closed via the corona. Subsequently a high electric current is formed, which leads to the generation of hard X-ray radiation in the dense chromosphere. The previously described idea is modelled and investigated by means of electric circuits. For this the microscopic plasma parameters, the magnetic field geometry and hard X-ray observations are used to obtain parameters for modelling macroscopic electric components, such as electric resistors, which are connected with each other. This model demonstrates that such a coronal electric current is correlated with large scale electric fields, which can accelerate the electrons quickly up to relativistic energies. The results of these calculations are encouraging. The electron fluxes predicted by the model are in agreement with the electron fluxes deduced from the measured photon fluxes. Additionally the model developed in this thesis proposes a new way to understand the observed double footpoint hard X-ray sources.
We develop a method of finding analytical sotutions of the Bogolyubov-de Gennes equations for the excitations of a Bose condensate in the Thomas-Fermi regime in harmonic traps of any asymmetry and introduce a classification of eigenstates. In the case of cylindrical symmetry we emphasize the presence of an accidental degeneracy in the excitation spectrum at certain values of the projection of orbital angular momentum on the symmetry axis and discuss possible consequences of the degeneracy in the context of new signatures of Bose- Einstein condensation
Next-generation sequencing methods provide comprehensive data for the analysis of structural and functional analysis of the genome. The draft genomes with low contig number and high N50 value can give insight into the structure of the genome as well as provide information on the annotation of the genome. In this study, we designed a pipeline that can be used to assemble prokaryotic draft genomes with low number of contigs and high N50 value. We aimed to use combination of two de novo assembly tools (SPAdes and IDBA-Hybrid) and evaluate the impact of this approach on the quality metrics of the assemblies. The followed pipeline was tested with the raw sequence data with short reads (< 300) for a total of 10 species from four different genera. To obtain the final draft genomes, we firstly assembled the sequences using SPAdes to find closely related organism using the extracted 16 s rRNA from it. IDBA-Hybrid assembler was used to obtain the second assembly data using the closely related organism genome. SPAdes assembler tool was implemented using the second assembly, produced by IDBA-hybrid as a hint. The results were evaluated using QUAST and BUSCO. The pipeline was successful for the reduction of the contig numbers and increasing the N50 statistical values in the draft genome assemblies while preserving the coverage of the draft genomes.
Measures for interoperability of phenotypic data: minimum information requirements and formatting
(2016)
Background: Plant phenotypic data shrouds a wealth of information which, when accurately analysed and linked to other data types, brings to light the knowledge about the mechanisms of life. As phenotyping is a field of research comprising manifold, diverse and time-consuming experiments, the findings can be fostered by reusing and combining existing datasets. Their correct interpretation, and thus replicability, comparability and interoperability, is possible provided that the collected observations are equipped with an adequate set of metadata. So far there have been no common standards governing phenotypic data description, which hampered data exchange and reuse. Results: In this paper we propose the guidelines for proper handling of the information about plant phenotyping experiments, in terms of both the recommended content of the description and its formatting. We provide a document called "Minimum Information About a Plant Phenotyping Experiment", which specifies what information about each experiment should be given, and a Phenotyping Configuration for the ISA-Tab format, which allows to practically organise this information within a dataset. We provide examples of ISA-Tab-formatted phenotypic data, and a general description of a few systems where the recommendations have been implemented. Conclusions: Acceptance of the rules described in this paper by the plant phenotyping community will help to achieve findable, accessible, interoperable and reusable data.
Migration and development in Senegal : a system dynamics analysis of the feedback relationships
(2011)
This thesis investigates the reciprocal relationship between migration and development in Senegal. Therewith, it contributes to the debate as to whether migration in developing countries enhances or rather impedes the development process. Even though extensive and controversial discussions can be found in the scientific literature regarding the impact of migration on development, research has scarcely examined the feedback relationships between migration and development. Science however agrees with both the fact that migration affects development as well as that the level of development in a country determines migration behaviour. Thus, both variables are neither dependent nor independent, but endogenous variables influencing each other and producing behavioural pattern that cannot be investigated using a static and unidirectional approach. On account of this, the thesis studies the feedback mechanisms existing between migration and development and the behavioural pattern generated by the high interdependence in order to be able to draw conclusions concerning the impact of changes in migration behaviour on the development process. To explore these research questions, the study applies the computer simulation method ‘System Dynamics’ and amplifies the simulation model for national development planning called ‘Threshold 21’ (T21), representing development processes endogenously and integrating economic, social and environmental aspects, using a structure that portrays the reasons and consequences of migration. The model has been customised to Senegal, being an appropriate representative of the theoretical interesting universe of cases. The comparison of the model generated scenarios - in which the intensity of emigration, the loss and gain of education, the remittances or the level of dependence changes - facilitates the analysis. The present study produces two important results. The first outcome is the development of an integrative framework representing migration and development in an endogenous way and incorporating several aspects of different theories. This model can be used as a starting point for further discussions and improvements and it is a fairly relevant and useful result against the background that migration is not integrated into most of the development planning tools despite its significant impact. The second outcome is the gained insights concerning the feedback relations between migration and development and the impact of changes in migration on development. To give two examples: It could be found that migration impacts development positively, indicated by HDI, but that the dominant behaviour of migration and development is a counteracting behaviour. That means that an increase in emigration leads to an improvement in development, while this in turn causes a decline in emigration, counterbalancing the initial increase. Another insight concerns the discovery that migration causes a decline in education in the short term, but leads to an increase in the long term, after approximately 25 years - a typical worse-before-better behaviour. From these and further observations, important policy implications can be derived for the sending and receiving countries. Hence, by overcoming the unidirectional perspective, this study contributes to an improved understanding of the highly complex relationship between migration and development and their feedback relations.
The pressure dependence of sheath gas assisted electrospray ionization (ESI) was investigated based on two complementary experimental setups, namely an ESI-ion mobility (IM) spectrometer and an ESI capillary - Faraday plate setup housed in an optically accessible vacuum chamber. The ESI-IM spectrometer is capable of working in the pressure range between 300 and 1000 mbar. Another aim was the assessment of the analytical capabilities of a subambient pressure ESI-IM spectrometer. The pressure dependence of ESI was characterized by imaging the electrospray and recording current-voltage (I-U) curves. Qualitatively different behavior was observed in both setups. While the current rises continuously with the voltage in the capillary-plate setup, a sharp increase of the current was measured in the IM spectrometer above a pressure-dependent threshold voltage. The different character can be attributed to the detection of different species in both experiments. In the capillary-plate experiment, a multitude of charged species are detected while only desolvated ions attribute to the IM spectrometer signal. This finding demonstrates the utility of IM spectrometry for the characterization of ESI, since in contrast to the capillary-plate setup, the release of ions from the electrospray droplets can be observed. The I-U curves change significantly with pressure. An important result is the reduction of the maximum current with decreasing pressure. The connected loss of ionization efficiency can be compensated by a more efficient transfer of ions in the IM spectrometer at increased E/N. Thus, similar limits of detection could be obtained at 500 mbar and 1 bar.
The capability of electrospray ionization (ESI)-ion mobility (IM) spectrometry for reaction monitoring is assessed both as a stand-alone real-time technique and in combination with HPLC. A three-step chemical reaction, consisting of a Williamson ether synthesis followed by a hydrogenation and an N-alkylation step, is chosen for demonstration. Intermediates and products are determined with a drift time to mass-per-charge correlation. Addition of an HPLC column to the setup increases the separation power and allows the determination of further species. Monitoring of the intensities of the various species over the reaction time allows the detection of the end of reaction, determination of the rate-limiting step, observation of the system response in discontinuous processes, and optimization of the mass ratios of the starting materials. However, charge competition in ESI influences the quantitative detection of substances in the reaction mixture. Therefore, two different methods are investigated, which allow the quantification and investigation of reaction kinetics. The first method is based on the pre-separation of the compounds on an HPLC column and their subsequent individual detection in the ESI-IM spectrometer. The second method involves an extended calibration procedure, which considers charge competition effects and facilitates nearly real-time quantification.
The application of electrospray ionization (ESI) ion mobility (IM) spectrometry on the detection end of a high-performance liquid chromatograph has been a subject of study for some time. So far, this method has been limited to low flow rates or has required splitting of the liquid flow. This work presents a novel concept of an ESI source facilitating the stable operation of the spectrometer at flow rates between 10 mu L min(-1) and 1500 mu L min(-1) without flow splitting, advancing the T-cylinder design developed by Kurnin and co-workers. Flow rates eight times faster than previously reported were achieved because of a more efficient dispersion of the liquid at increased electrospray voltages combined with nebulization by a sheath gas. Imaging revealed the spray operation to be in a rotationally symmetric multijet-mode. The novel ESI-IM spectrometer tolerates high water contents (<= 90%) and electrolyte concentrations up to 10 mM, meeting another condition required of high-performance liquid chromatography (HPLC) detectors. Limits of detection of 50 nM for promazine in the positive mode and 1 mu M for 1,3-dinitrobenzene in the negative mode were established. Three mixtures of reduced complexity (five surfactants, four neuroleptics, and two isomers) were separated in the millisecond regime in stand-alone operation of the spectrometer. Separations of two more complex mixtures (five neuroleptics and 13 pesticides) demonstrate the application of the spectrometer as an HPLC detector. The examples illustrate the advantages of the spectrometer over the established diode array detector, in terms of additional IM separation of substances not fully separated in the retention time domain as well as identification of substances based on their characteristic IMs.
The combination of high-performance liquid chromatography and electrospray ionization ion mobility spectrometry facilitates the two-dimensional separation of complex mixtures in the retention and drift time plane. The ion mobility spectrometer presented here was optimized for flow rates customarily used in high-performance liquid chromatography between 100 and 1500 mu L/min. The characterization of the system with respect to such parameters as the peak capacity of each time dimension and of the 2D spectrum was carried out based on a separation of a pesticide mixture containing 24 substances. While the total ion current chromatogram is coarsely resolved, exhibiting coelutions for a number of compounds, all substances can be separately detected in the 2D plane due to the orthogonality of the separations in retention and drift dimensions. Another major advantage of the ion mobility detector is the identification of substances based on their characteristic mobilities. Electrospray ionization allows the detection of substances lacking a chromophore. As an example, the separation of a mixture of 18 amino acids is presented. A software built upon the free mass spectrometry package OpenMS was developed for processing the extensive 2D data. The different processing steps are implemented as separate modules which can be arranged in a graphic workflow facilitating automated processing of data.
The increasing development of antibiotic resistance in bacteria has been a major problem for years, both in human and veterinary medicine. Prophylactic measures, such as the use of vaccines, are of great importance in reducing the use of antibiotics in livestock. These vaccines are mainly produced based on formaldehyde inactivation. However, the latter damages the recognition elements of the bacterial proteins and thus could reduce the immune response in the animal. An alternative inactivation method developed in this work is based on gentle photodynamic inactivation using carbon nanodots (CNDs) at excitation wavelengths λex > 290 nm. The photodynamic inactivation was characterized on the nonvirulent laboratory strain Escherichia coli K12 using synthesized CNDs. For a gentle inactivation, the CNDs must be absorbed into the cytoplasm of the E. coli cell. Thus, the inactivation through photoinduced formation of reactive oxygen species only takes place inside the bacterium, which means that the outer membrane is neither damaged nor altered. The loading of the CNDs into E. coli was examined using fluorescence microscopy. Complete loading of the bacterial cells could be achieved in less than 10 min. These studies revealed a reversible uptake process allowing the recovery and reuse of the CNDs after irradiation and before the administration of the vaccine. The success of photodynamic inactivation was verified by viability assays on agar. In a homemade flow photoreactor, the fastest successful irradiation of the bacteria could be carried out in 34 s. Therefore, the photodynamic inactivation based on CNDs is very effective. The membrane integrity of the bacteria after irradiation was verified by slide agglutination and atomic force microscopy. The method developed for the laboratory strain E. coli K12 could then be successfully applied to the important avian pathogens Bordetella avium and Ornithobacterium rhinotracheale to aid the development of novel vaccines.
The increasing development of antibiotic resistance in bacteria has been a major problem for years, both in human and veterinary medicine. Prophylactic measures, such as the use of vaccines, are of great importance in reducing the use of antibiotics in livestock. These vaccines are mainly produced based on formaldehyde inactivation. However, the latter damages the recognition elements of the bacterial proteins and thus could reduce the immune response in the animal. An alternative inactivation method developed in this work is based on gentle photodynamic inactivation using carbon nanodots (CNDs) at excitation wavelengths λex > 290 nm. The photodynamic inactivation was characterized on the nonvirulent laboratory strain Escherichia coli K12 using synthesized CNDs. For a gentle inactivation, the CNDs must be absorbed into the cytoplasm of the E. coli cell. Thus, the inactivation through photoinduced formation of reactive oxygen species only takes place inside the bacterium, which means that the outer membrane is neither damaged nor altered. The loading of the CNDs into E. coli was examined using fluorescence microscopy. Complete loading of the bacterial cells could be achieved in less than 10 min. These studies revealed a reversible uptake process allowing the recovery and reuse of the CNDs after irradiation and before the administration of the vaccine. The success of photodynamic inactivation was verified by viability assays on agar. In a homemade flow photoreactor, the fastest successful irradiation of the bacteria could be carried out in 34 s. Therefore, the photodynamic inactivation based on CNDs is very effective. The membrane integrity of the bacteria after irradiation was verified by slide agglutination and atomic force microscopy. The method developed for the laboratory strain E. coli K12 could then be successfully applied to the important avian pathogens Bordetella avium and Ornithobacterium rhinotracheale to aid the development of novel vaccines.
The knowledge of the largest expected earthquake magnitude in a region is one of the key issues in probabilistic seismic hazard calculations and the estimation of worst-case scenarios. Earthquake catalogues are the most informative source of information for the inference of earthquake magnitudes. We analysed the earthquake catalogue for Central Asia with respect to the largest expected magnitudes m(T) in a pre-defined time horizon T-f using a recently developed statistical methodology, extended by the explicit probabilistic consideration of magnitude errors. For this aim, we assumed broad error distributions for historical events, whereas the magnitudes of recently recorded instrumental earthquakes had smaller errors. The results indicate high probabilities for the occurrence of large events (M >= 8), even in short time intervals of a few decades. The expected magnitudes relative to the assumed maximum possible magnitude are generally higher for intermediate-depth earthquakes (51-300 km) than for shallow events (0-50 km). For long future time horizons, for example, a few hundred years, earthquakes with M >= 8.5 have to be taken into account, although, apart from the 1889 Chilik earthquake, it is probable that no such event occurred during the observation period of the catalogue.
Earthquake catalogs are probably the most informative data source about spatiotemporal seismicity evolution. The catalog quality in one of the most active seismogenic zones in the world, Japan, is excellent, although changes in quality arising, for example, from an evolving network are clearly present. Here, we seek the best estimate for the largest expected earthquake in a given future time interval from a combination of historic and instrumental earthquake catalogs. We extend the technique introduced by Zoller et al. (2013) to estimate the maximum magnitude in a time window of length T-f for earthquake catalogs with varying level of completeness. In particular, we consider the case in which two types of catalogs are available: a historic catalog and an instrumental catalog. This leads to competing interests with respect to the estimation of the two parameters from the Gutenberg-Richter law, the b-value and the event rate lambda above a given lower-magnitude threshold (the a-value). The b-value is estimated most precisely from the frequently occurring small earthquakes; however, the tendency of small events to cluster in aftershocks, swarms, etc. violates the assumption of a Poisson process that is used for the estimation of lambda. We suggest addressing conflict by estimating b solely from instrumental seismicity and using large magnitude events from historic catalogs for the earthquake rate estimation. Applying the method to Japan, there is a probability of about 20% that the maximum expected magnitude during any future time interval of length T-f = 30 years is m >= 9.0. Studies of different subregions in Japan indicates high probabilities for M 8 earthquakes along the Tohoku arc and relatively low probabilities in the Tokai, Tonankai, and Nankai region. Finally, for scenarios related to long-time horizons and high-confidence levels, the maximum expected magnitude will be around 10.
We show how the maximum magnitude within a predefined future time horizon may be estimated from an earthquake catalog within the context of Gutenberg-Richter statistics. The aim is to carry out a rigorous uncertainty assessment, and calculate precise confidence intervals based on an imposed level of confidence a. In detail, we present a model for the estimation of the maximum magnitude to occur in a time interval T-f in the future, given a complete earthquake catalog for a time period T in the past and, if available, paleoseismic events. For this goal, we solely assume that earthquakes follow a stationary Poisson process in time with unknown productivity Lambda and obey the Gutenberg-Richter law in magnitude domain with unknown b-value. The random variables. and b are estimated by means of Bayes theorem with noninformative prior distributions. Results based on synthetic catalogs and on retrospective calculations of historic catalogs from the highly active area of Japan and the low-seismicity, but high-risk region lower Rhine embayment (LRE) in Germany indicate that the estimated magnitudes are close to the true values. Finally, we discuss whether the techniques can be extended to meet the safety requirements for critical facilities such as nuclear power plants. For this aim, the maximum magnitude for all times has to be considered. In agreement with earlier work, we find that this parameter is not a useful quantity from the viewpoint of statistical inference.
The injection of fluids is a well-known origin for the triggering of earthquake sequences. The growing number of projects related to enhanced geothermal systems, fracking, and others has led to the question, which maximum earthquake magnitude can be expected as a consequence of fluid injection? This question is addressed from the perspective of statistical analysis. Using basic empirical laws of earthquake statistics, we estimate the magnitude M-T of the maximum expected earthquake in a predefined future time window T-f. A case study of the fluid injection site at Paradox Valley, Colorado, demonstrates that the magnitude m 4.3 of the largest observed earthquake on 27 May 2000 lies very well within the expectation from past seismicity without adjusting any parameters. Vice versa, for a given maximum tolerable earthquake at an injection site, we can constrain the corresponding amount of injected fluids that must not be exceeded within predefined confidence bounds.
The Groningen gas field serves as a natural laboratory for production-induced earthquakes, because no earthquakes were observed before the beginning of gas production. Increasing gas production rates resulted in growing earthquake activity and eventually in the occurrence of the 2012M(w) 3.6 Huizinge earthquake. At least since this event, a detailed seismic hazard and risk assessment including estimation of the maximum earthquake magnitude is considered to be necessary to decide on the future gas production. In this short note, we first apply state-of-the-art methods of mathematical statistics to derive confidence intervals for the maximum possible earthquake magnitude m(max). Second, we calculate the maximum expected magnitude M-T in the time between 2016 and 2024 for three assumed gas-production scenarios. Using broadly accepted physical assumptions and 90% confidence level, we suggest a value of m(max) 4.4, whereas M-T varies between 3.9 and 4.3, depending on the production scenario.
In the present study, we summarize and evaluate the endeavors from recent years to estimate the maximum possible earthquake magnitude m(max) from observed data. In particular, we use basic and physically motivated assumptions to identify best cases and worst cases in terms of lowest and highest degree of uncertainty of m(max). In a general framework, we demonstrate that earthquake data and earthquake proxy data recorded in a fault zone provide almost no information about m(max) unless reliable and homogeneous data of a long time interval, including several earthquakes with magnitude close to m(max), are available. Even if detailed earthquake information from some centuries including historic and paleoearthquakes are given, only very few, namely the largest events, will contribute at all to the estimation of m(max), and this results in unacceptably high uncertainties. As a consequence, estimators of m(max) in a fault zone, which are based solely on earthquake-related information from this region, have to be dismissed.
Based on an analysis of continuous monitoring of farm animal behavior in the region of the 2016 M6.6 Norcia earthquake in Italy, Wikelski et al., 2020; (Seismol Res Lett, 89, 2020, 1238) conclude that animal activity can be anticipated with subsequent seismic activity and that this finding might help to design a "short-term earthquake forecasting method." We show that this result is based on an incomplete analysis and misleading interpretations. Applying state-of-the-art methods of statistics, we demonstrate that the proposed anticipatory patterns cannot be distinguished from random patterns, and consequently, the observed anomalies in animal activity do not have any forecasting power.
We present a Bayesian method that allows continuous updating the aperiodicity of the recurrence time distribution of large earthquakes based on a catalog with magnitudes above a completeness threshold. The approach uses a recently proposed renewal model for seismicity and allows the inclusion of magnitude uncertainties in a straightforward manner. Errors accounting for grouped magnitudes and random errors are studied and discussed. The results indicate that a stable and realistic value of the aperiodicity can be predicted in an early state of seismicity evolution, even though only a small number of large earthquakes has occurred to date. Furthermore, we demonstrate that magnitude uncertainties can drastically influence the results and can therefore not be neglected. We show how to correct for the bias caused by magnitude errors. For the region of Parkfield we find that the aperiodicity, or the coefficient of variation, is clearly higher than in studies which are solely based on the large earthquakes.
We investigate spatio-temporal properties of earthquake patterns in the San Jacinto fault zone (SJFZ), California, between Cajon Pass and the Superstition Hill Fault, using a long record of simulated seismicity constrained by available seismological and geological data. The model provides an effective realization of a large segmented strike-slip fault zone in a 3D elastic half-space, with heterogeneous distribution of static friction chosen to represent several clear step-overs at the surface. The simulated synthetic catalog reproduces well the basic statistical features of the instrumental seismicity recorded at the SJFZ area since 1981. The model also produces events larger than those included in the short instrumental record, consistent with paleo-earthquakes documented at sites along the SJFZ for the last 1,400 years. The general agreement between the synthetic and observed data allows us to address with the long-simulated seismicity questions related to large earthquakes and expected seismic hazard. The interaction between m a parts per thousand yen 7 events on different sections of the SJFZ is found to be close to random. The hazard associated with m a parts per thousand yen 7 events on the SJFZ increases significantly if the long record of simulated seismicity is taken into account. The model simulations indicate that the recent increased number of observed intermediate SJFZ earthquakes is a robust statistical feature heralding the occurrence of m a parts per thousand yen 7 earthquakes. The hypocenters of the m a parts per thousand yen 5 events in the simulation results move progressively towards the hypocenter of the upcoming m a parts per thousand yen 7 earthquake.
Kijko et al. (2016) present various methods to estimate parameters that are relevant for probabilistic seismic-hazard assessment. One of these parameters, although not the most influential, is the maximum possible earthquake magnitude m(max). I show that the proposed estimation of m(max) is based on an erroneous equation related to a misuse of the estimator in Cooke (1979) and leads to unstable results. So far, reported finite estimations of m(max) arise from data selection, because the estimator in Kijko et al. (2016) diverges with finite probability. This finding is independent of the assumed distribution of earthquake magnitudes. For the specific choice of the doubly truncated Gutenberg-Richter distribution, I illustrate the problems by deriving explicit equations. Finally, I conclude that point estimators are generally not a suitable approach to constrain m(max).
Extreme value statistics is a popular and frequently used tool to model the occurrence of large earthquakes. The problem of poor statistics arising from rare events is addressed by taking advantage of the validity of general statistical properties in asymptotic regimes. In this note, I argue that the use of extreme value statistics for the purpose of practically modeling the tail of the frequency-magnitude distribution of earthquakes can produce biased and thus misleading results because it is unknown to what degree the tail of the true distribution is sampled by data. Using synthetic data allows to quantify this bias in detail. The implicit assumption that the true M-max is close to the maximum observed magnitude M-max,M-observed restricts the class of the potential models a priori to those with M-max = M-max,M-observed + Delta M with an increment Delta M approximate to 0.5... 1.2. This corresponds to the simple heuristic method suggested by Wheeler (2009) and labeled :M-max equals M-obs plus an increment." The incomplete consideration of the entire model family for the frequency-magnitude distribution neglects, however, the scenario of a large so far unobserved earthquake.
The occurrence of earthquakes is characterized by a high degree of spatiotemporal complexity. Although numerous patterns, e.g. fore- and aftershock sequences, are well-known, the underlying mechanisms are not observable and thus not understood. Because the recurrence times of large earthquakes are usually decades or centuries, the number of such events in corresponding data sets is too small to draw conclusions with reasonable statistical significance. Therefore, the present study combines both, numerical modeling and analysis of real data in order to unveil the relationships between physical mechanisms and observational quantities. The key hypothesis is the validity of the so-called "critical point concept" for earthquakes, which assumes large earthquakes to occur as phase transitions in a spatially extended many-particle system, similar to percolation models. New concepts are developed to detect critical states in simulated and in natural data sets. The results indicate that important features of seismicity like the frequency-size distribution and the temporal clustering of earthquakes depend on frictional and structural fault parameters. In particular, the degree of quenched spatial disorder (the "roughness") of a fault zone determines whether large earthquakes occur quasiperiodically or more clustered. This illustrates the power of numerical models in order to identify regions in parameter space, which are relevant for natural seismicity. The critical point concept is verified for both, synthetic and natural seismicity, in terms of a critical state which precedes a large earthquake: a gradual roughening of the (unobservable) stress field leads to a scale-free (observable) frequency-size distribution. Furthermore, the growth of the spatial correlation length and the acceleration of the seismic energy release prior to large events is found. The predictive power of these precursors is, however, limited. Instead of forecasting time, location, and magnitude of individual events, a contribution to a broad multiparameter approach is encouraging.