Antiplasmodial β-hydroxydihydrochalcone from seedpods of Tephrosia elata

From the seedpods of Tephrosia elata, a new β-hydroxydihydrochalcone named (S)-elatadihydrochalcone was isolated. In addition, the known flavonoids obovatachalcone, obovatin, obovatin methyl ether and deguelin were identified. The structures were determined on the basis of spectroscopic evidence. The crude extract and the flavonoids obtained from the seedpods of this plant showed antiplasmodial activities. The literature NMR data on β-hydroxydihydrochalcones is reviewed and the identity of some of the compounds assigned β-hydroxydihydrochalcone skeleton is questioned.

Metadaten
Author details:	Martin G. Peter, Lois M. Muiva, Abiy Yenesew ORCiD, Solomon Derese ORCiD, Matthias Heydenreich ORCiD, Hoseah M. Akala ORCiD, Fredrick Eyase, Norman C. Waters, Charles Mutai, Joseph M. Keriko, Douglas S. Walsh
URN:	urn:nbn:de:kobv:517-opus-44437
Publication series (Volume number):	Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe (paper 118)
Publication type:	Postprint
Language:	English
Publication year:	2009
Publishing institution:	Universität Potsdam
Release date:	2010/07/05
Tag:	(S)-Elatadihydrochalcone; Leguminosae; Seedpods; Tephrosia elata; β-Hydroxydihydrochalcone
Source:	Phytochemistry letters 2 (2009), 3, S. 99 - 102, DOI 10.1016/j.phytol.2009.01.002
Organizational units:	Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie
DDC classification:	5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften
License (German):	Keine öffentliche Lizenz: Unter Urheberrechtsschutz
External remark:	The article was originally published by: Elsevier Phytochemistry letters. - 2 (2009), 3, S. 99-102 ISSN 1874-3900 DOI 10.1016/j.phytol.2009.01.002