Niko Beerenwinkel, Tobias Sing, Thomas Lengauer, Joerg Rahnenfuhrer, Kirsten Roomp, Igor Savenkov, Roman Fischer, Daniel Hoffmann, Joachim Selbig, Klaus Korn, Hauke Walter, Thomas Berg, Patrick Braun, Gerd Faetkenheuer, Mark Oette, Juergen Rockstroh, Bernd Kupfer, Rolf Kaiser, Martin Daeumer
- The development of drug resistance is a major obstacle to successful treatment of HIV infection. The extraordinary replication dynamics of HIV facilitates its escape from selective pressure exerted by the human immune system and by combination drug therapy. We have developed several computational methods whose combined use can support the design of optimal antiretroviral therapies based on viral genomic data