Two unusual rotenoid derivatives, 7a-O-methyl-12a-hydroxydeguelol and spiro-13-homo-13-oxaelliptone, from the seeds of Derris trifoliata
- The crude methanol extract of the seeds of Derris trifoliata showed potent and dose dependent larvicidal activity against the 2nd instar larvae of Aedes aegypti. From this extract two unusual rotenoid derivatives, a rotenoloid (named 7a-O-methyl-12a-hydroxydeguelol) and a spirohomooxarotenoid (named spiro-13-homo-13-oxaelliptone), were isolated and characterised. In addition a rare natural chromanone (6,7-dimethoxy-4-chromanone) and the known rotenoids rotenone, tephrosin and dehydrodeguelin were identified. The structures were assigned on the basis of spectroscopic evidence. The larvicidal activity of the crude extract is mainly due to rotenone. (c) 2006 Elsevier Ltd. All rights reserved
| Author details: | Abiy YenesewORCiD, John T. Kiplagat, Solomon DereseORCiD, Jacob O. Midiwo, Jacques M. Kabaru, Matthias HeydenreichORCiD, Martin G. Peter |
|---|---|
| URL: | http://www.sciencedirect.com/science/article/pii/S0031942206000045 |
| DOI: | https://doi.org/10.1016/j.phytochem.2006.01.002 |
| Publication type: | Article |
| Language: | English |
| Year of first publication: | 2006 |
| Publication year: | 2006 |
| Release date: | 2017/03/24 |
| Source: | Phytochemistry. - 67 (2006), 10, S. 988 - 991 |
| Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie |
| Peer review: | Referiert |
