A short and efficient route from myo- to neo-inositol
- An efficient route from myo- to neo-inositol is described. The key steps of the sequence are oxidation of the hydroxy group at C-5 to the corresponding ketone, followed by a highly (dr = 7.8:1) stereoselective reduction. The route includes nine steps with an overall yield of 51% and is therefore superior to all hitherto reported methods for the preparation of neo-inositol.
| Author details: | Pablo WessigORCiDGND, Kristian Möllnitz, Sebastian Hübner |
|---|---|
| URL: | http://www.thieme-connect.com/ejournals/toc/synlett |
| DOI: | https://doi.org/10.1055/s-0029-1220071 |
| ISSN: | 0936-5214 |
| Publication type: | Article |
| Language: | English |
| Year of first publication: | 2010 |
| Publication year: | 2010 |
| Release date: | 2017/03/25 |
| Source: | Synlett. - ISSN 0936-5214. - (2010), 10, S. 1497 - 1500 |
| Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie |
| Peer review: | Referiert |
