TY - JOUR A1 - Mattern, Maximilian A1 - Pudell, Jan-Etienne A1 - Dumesnil, Karine A1 - Reppert, Alexander von A1 - Bargheer, Matias T1 - Towards shaping picosecond strain pulses via magnetostrictive transducers JF - Photoacoustics N2 - Using time-resolved x-ray diffraction, we demonstrate the manipulation of the picosecond strain response of a metallic heterostructure consisting of a dysprosium (Dy) transducer and a niobium (Nb) detection layer by an external magnetic field. We utilize the first-order ferromagnetic–antiferromagnetic phase transition of the Dy layer, which provides an additional large contractive stress upon laser excitation compared to its zerofield response. This enhances the laser-induced contraction of the transducer and changes the shape of the picosecond strain pulses driven in Dy and detected within the buried Nb layer. Based on our experiment with rare-earth metals we discuss required properties for functional transducers, which may allow for novel field-control of the emitted picosecond strain pulses. KW - picosecond ultrasonics KW - magnetostriction KW - ultrafast x-ray diffraction KW - ultrafast photoacoustics KW - nanoscale heat transfer KW - negative thermal expansion Y1 - 2023 U6 - https://doi.org/10.1016/j.pacs.2023.100463 SN - 2213-5979 VL - 30 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Seleem, Omar A1 - Ayzel, Georgy A1 - Costa Tomaz de Souza, Arthur A1 - Bronstert, Axel A1 - Heistermann, Maik T1 - Towards urban flood susceptibility mapping using data-driven models in Berlin, Germany JF - Geomatics, natural hazards and risk N2 - Identifying urban pluvial flood-prone areas is necessary but the application of two-dimensional hydrodynamic models is limited to small areas. Data-driven models have been showing their ability to map flood susceptibility but their application in urban pluvial flooding is still rare. A flood inventory (4333 flooded locations) and 11 factors which potentially indicate an increased hazard for pluvial flooding were used to implement convolutional neural network (CNN), artificial neural network (ANN), random forest (RF) and support vector machine (SVM) to: (1) Map flood susceptibility in Berlin at 30, 10, 5, and 2 m spatial resolutions. (2) Evaluate the trained models' transferability in space. (3) Estimate the most useful factors for flood susceptibility mapping. The models' performance was validated using the Kappa, and the area under the receiver operating characteristic curve (AUC). The results indicated that all models perform very well (minimum AUC = 0.87 for the testing dataset). The RF models outperformed all other models at all spatial resolutions and the RF model at 2 m spatial resolution was superior for the present flood inventory and predictor variables. The majority of the models had a moderate performance for predictions outside the training area based on Kappa evaluation (minimum AUC = 0.8). Aspect and altitude were the most influencing factors on the image-based and point-based models respectively. Data-driven models can be a reliable tool for urban pluvial flood susceptibility mapping wherever a reliable flood inventory is available. KW - Urban pluvial flood susceptibility KW - convolutional neural network KW - deep KW - learning KW - random forest KW - support vector machine KW - spatial resolution; KW - flood predictors Y1 - 2022 U6 - https://doi.org/10.1080/19475705.2022.2097131 SN - 1947-5705 SN - 1947-5713 VL - 13 IS - 1 SP - 1640 EP - 1662 PB - Taylor & Francis CY - London ER - TY - JOUR A1 - Eckert, Silvia A1 - Herden, Jasmin A1 - Stift, Marc A1 - Durka, Walter A1 - Kleunen, Mark van A1 - Joshi, Jasmin T1 - Traces of genetic but not epigenetic adaptation in the invasive goldenrod Solidago canadensis despite the absence of population structure JF - Frontiers in Ecology and Evolution N2 - Biological invasions may result from multiple introductions, which might compensate for reduced gene pools caused by bottleneck events, but could also dilute adaptive processes. A previous common-garden experiment showed heritable latitudinal clines in fitness-related traits in the invasive goldenrod Solidago canadensis in Central Europe. These latitudinal clines remained stable even in plants chemically treated with zebularine to reduce epigenetic variation. However, despite the heritability of traits investigated, genetic isolation-by-distance was non-significant. Utilizing the same specimens, we applied a molecular analysis of (epi)genetic differentiation with standard and methylation-sensitive (MSAP) AFLPs. We tested whether this variation was spatially structured among populations and whether zebularine had altered epigenetic variation. Additionally, we used genome scans to mine for putative outlier loci susceptible to selection processes in the invaded range. Despite the absence of isolation-by-distance, we found spatial genetic neighborhoods among populations and two AFLP clusters differentiating northern and southern Solidago populations. Genetic and epigenetic diversity were significantly correlated, but not linked to phenotypic variation. Hence, no spatial epigenetic patterns were detected along the latitudinal gradient sampled. Applying genome-scan approaches (BAYESCAN, BAYESCENV, RDA, and LFMM), we found 51 genetic and epigenetic loci putatively responding to selection. One of these genetic loci was significantly more frequent in populations at the northern range. Also, one epigenetic locus was more frequent in populations in the southern range, but this pattern was lost under zebularine treatment. Our results point to some genetic, but not epigenetic adaptation processes along a large-scale latitudinal gradient of S. canadensis in its invasive range. KW - AFLP KW - MSAP KW - cytosine methylation KW - spatial autocorrelation KW - genome scan Y1 - 2022 U6 - https://doi.org/10.3389/fevo.2022.856453 SN - 2296-701X VL - 10 SP - 1 EP - 17 PB - Frontiers CY - Lausanne, Schweiz ER - TY - JOUR A1 - Timme, Sinika A1 - Wolff, Wanja A1 - Englert, Chris A1 - Brand, Ralf T1 - Tracking Self-Control – Task Performance and Pupil Size in a Go/No-Go Inhibition Task JF - Frontiers in Psychology N2 - There is an ongoing debate about how to test and operationalize self-control. This limited understanding is in large part due to a variety of different tests and measures used to assess self-control, as well as the lack of empirical studies examining the temporal dynamics during the exertion of self-control. In order to track changes that occur over the course of exposure to a self-control task, we investigate and compare behavioral, subjective, and physiological indicators during the exertion of self-control. Participants completed both a task requiring inhibitory control (Go/No-Go task) and a control task (two-choice task). Behavioral performance and pupil size were measured during the tasks. Subjective vitality was measured before and after the tasks. While pupil size and subjective vitality showed similar trajectories in the two tasks, behavioral performance decreased in the inhibitory control-demanding task, but not in the control task. However, behavioral, subjective, and physiological measures were not significantly correlated. These results suggest that there is a disconnect between different measures of self-control with high intra- and interindividual variability. Theoretical and methodological implications for self-control theory and future empirical work are discussed. KW - self-control KW - response inhibition KW - psychophysiological KW - behavioral and self-report measures KW - pupil diameter Y1 - 2022 U6 - https://doi.org/10.3389/fpsyg.2022.915016 SN - 1664-1078 VL - 13 PB - Frontiers CY - Lausanne, Schweiz ER - TY - JOUR A1 - Madruga de Brito, Mariana A1 - Otto, Danny A1 - Kuhlicke, Christian T1 - Tracking topics and frames regarding sustainability transformations during the onset of the COVID-19 crisis JF - Sustainability / Multidisciplinary Digital Publishing Institute (MDPI) N2 - Many researchers and politicians believe that the COVID-19 crisis may have opened a "window of opportunity " to spur sustainability transformations. Still, evidence for such a dynamic is currently lacking. Here, we propose the linkage of "big data " and "thick data " methods for monitoring debates on transformation processes by following the COVID-19 discourse on ecological sustainability in Germany. We analysed variations in the topics discussed by applying text mining techniques to a corpus with 84,500 newspaper articles published during the first COVID-19 wave. This allowed us to attain a unique and previously inaccessible "bird's eye view " of how these topics evolved. To deepen our understanding of prominent frames, a qualitative content analysis was undertaken. Furthermore, we investigated public awareness by analysing online search behaviour. The findings show an underrepresentation of sustainability topics in the German news during the early stages of the crisis. Similarly, public awareness regarding climate change was found to be reduced. Nevertheless, by examining the newspaper data in detail, we found that the pandemic is often seen as a chance for sustainability transformations-but not without a set of challenges. Our mixed-methods approach enabled us to bridge knowledge gaps between qualitative and quantitative research by "thickening " and providing context to data-driven analyses. By monitoring whether or not the current crisis is seen as a chance for sustainability transformations, we provide insights for environmental policy in times of crisis. KW - frames KW - SDG KW - green deal KW - content analysis KW - natural language processing KW - NLP Y1 - 2021 U6 - https://doi.org/10.3390/su131911095 SN - 2071-1050 VL - 13 IS - 19 PB - MDPI CY - Basel ER - TY - JOUR A1 - Wiebking, Christine A1 - Lin, Chiao-I A1 - Wippert, Pia-Maria T1 - Training intervention effects on cognitive performance and neuronal plasticity — A pilot study JF - Frontiers in Neurology, section Neurorehabilitation N2 - Studies suggest that people suffering from chronic pain may have altered brain plasticity, along with altered functional connectivity between pain-processing brain regions. These may be related to decreased mood and cognitive performance. There is some debate as to whether physical activity combined with behavioral therapy (e.g. cognitive distraction, body scan) may counteract these changes. However, underlying neuronal mechanisms are unclear. The aim of the current pilot study with a 3-armed randomized controlled trial design was to examine the effects of sensorimotor training for nonspecific chronic low back pain on (1) cognitive performance; (2) fMRI activity co-fluctuations (functional connectivity) between pain-related brain regions; and (3) the relationship between functional connectivity and subjective variables (pain and depression). Six hundred and sixty two volunteers with non-specific chronic low back pain were randomly allocated to a unimodal (sensorimotor training), multidisciplinary (sensorimotor training and behavioral therapy) intervention, or to a control group within a multicenter study. A subsample of patients (n = 21) from one study center participated in the pilot study presented here. Measurements were at baseline, during (3 weeks, M2) and after intervention (12 weeks, M4 and 24 weeks, M5). Cognitive performance was measured by the Trail Making Test and functional connectivity by MRI. Pain perception and depression were assessed by the Von Korff questionnaire and the Hospital and Anxiety. Group differences were calculated by univariate and repeated ANOVA measures and Bayesian statistics; correlations by Pearson's r. Change and correlation of functional connection were analyzed within a pooled intervention group (uni-, multidisciplinary group). Results revealed that participants with increased pain intensity at baseline showed higher functional connectivity between pain-related brain areas used as ROIs in this study. Though small sample sizes limit generalization, cognitive performance increased in the multimodal group. Increased functional connectivity was observed in participants with increased pain ratings. Pain ratings and connectivity in pain-related brain regions decreased after the intervention. The results provide preliminary indication that intervention effects can potentially be achieved on the cognitive and neuronal level. The intervention may be suitable for therapy and prevention of non-specific chronic low back pain. KW - chronic back pain KW - sensorimotor training intervention KW - multimodal intervention KW - MRI KW - neuroplasticity Y1 - 2022 U6 - https://doi.org/10.3389/fneur.2022.773813 SN - 1664-2295 VL - 13 PB - Frontiers CY - Lausanne, Schweiz ER - TY - JOUR A1 - Bergholz, Kolja A1 - Kober, Klarissa A1 - Jeltsch, Florian A1 - Schmidt, Kristina A1 - Weiß, Lina T1 - Trait means or variance BT - What determines plant species' local and regional occurrence in fragmented dry grasslands? JF - Ecology and evolution N2 - One of the few laws in ecology is that communities consist of few common and many rare taxa. Functional traits may help to identify the underlying mechanisms of this community pattern, since they correlate with different niche dimensions. However, comprehensive studies are missing that investigate the effects of species mean traits (niche position) and intraspecific trait variability (ITV, niche width) on species abundance. In this study, we investigated fragmented dry grasslands to reveal trait-occurrence relationships in plants at local and regional scales. We predicted that (a) at the local scale, species occurrence is highest for species with intermediate traits, (b) at the regional scale, habitat specialists have a lower species occurrence than generalists, and thus, traits associated with stress-tolerance have a negative effect on species occurrence, and (c) ITV increases species occurrence irrespective of the scale. We measured three plant functional traits (SLA = specific leaf area, LDMC = leaf dry matter content, plant height) at 21 local dry grassland communities (10 m × 10 m) and analyzed the effect of these traits and their variation on species occurrence. At the local scale, mean LDMC had a positive effect on species occurrence, indicating that stress-tolerant species are the most abundant rather than species with intermediate traits (hypothesis 1). We found limited support for lower specialist occurrence at the regional scale (hypothesis 2). Further, ITV of LDMC and plant height had a positive effect on local occurrence supporting hypothesis 3. In contrast, at the regional scale, plants with a higher ITV of plant height were less frequent. We found no evidence that the consideration of phylogenetic relationships in our analyses influenced our findings. In conclusion, both species mean traits (in particular LDMC) and ITV were differently related to species occurrence with respect to spatial scale. Therefore, our study underlines the strong scale-dependency of trait-abundance relationships. KW - LMA KW - niche width KW - plant functional trait KW - scale-dependency KW - species abundance KW - trait-environment relationship Y1 - 2020 U6 - https://doi.org/10.1002/ece3.7287 SN - 2045-7758 VL - 11 IS - 7 SP - 3357 EP - 3365 PB - John Wiley & Sons, Inc. ER - TY - JOUR A1 - Canitz, Julia A1 - Kirschbaum, Frank A1 - Tiedemann, Ralph T1 - Transcriptome-wide single nucleotide polymorphisms related to electric organ discharge differentiation among African weakly electric fish species JF - PLoS one N2 - African weakly electric fish of the mormyrid genus Campylomormyrus generate pulse-type electric organ discharges (EODs) for orientation and communication. Their pulse durations are species-specific and elongated EODs are a derived trait. So far, differential gene expression among tissue-specific transcriptomes across species with different pulses and point mutations in single ion channel genes indicate a relation of pulse duration and electrocyte geometry/excitability. However, a comprehensive assessment of expressed Single Nucleotide Polymorphisms (SNPs) throughout the entire transcriptome of African weakly electric fish, with the potential to identify further genes influencing EOD duration, is still lacking. This is of particular value, as discharge duration is likely based on multiple cellular mechanisms and various genes. Here we provide the first transcriptome-wide SNP analysis of African weakly electric fish species (genus Campylomormyrus) differing by EOD duration to identify candidate genes and cellular mechanisms potentially involved in the determination of an elongated discharge of C. tshokwe. Non-synonymous substitutions specific to C. tshokwe were found in 27 candidate genes with inferred positive selection among Campylomormyrus species. These candidate genes had mainly functions linked to transcriptional regulation, cell proliferation and cell differentiation. Further, by comparing gene annotations between C. compressirostris (ancestral short EOD) and C. tshokwe (derived elongated EOD), we identified 27 GO terms and 2 KEGG pathway categories for which C. tshokwe significantly more frequently exhibited a species-specific expressed substitution than C. compressirostris. The results indicate that transcriptional regulation as well cell proliferation and differentiation take part in the determination of elongated pulse durations in C. tshokwe. Those cellular processes are pivotal for tissue morphogenesis and might determine the shape of electric organs supporting the observed correlation between electrocyte geometry/tissue structure and discharge duration. The inferred expressed SNPs and their functional implications are a valuable resource for future investigations on EOD durations. Y1 - 2020 U6 - https://doi.org/10.1371/journal.pone.0240812 SN - 1932-6203 VL - 15 IS - 10 PB - PLoS CY - San Francisco, California, US ER - TY - JOUR A1 - Apriyanto, Ardha A1 - Compart, Julia A1 - Fettke, Jörg T1 - Transcriptomic analysis of mesocarp tissue during fruit development of the oil palm revealed specific isozymes related to starch metabolism that control oil yield JF - Frontiers in plant science N2 - The oil palm (Elaeis guineensis Jacq.) produces a large amount of oil from the fruit. However, increasing the oil production in this fruit is still challenging. A recent study has shown that starch metabolism is essential for oil synthesis in fruit-producing species. Therefore, the transcriptomic analysis by RNA-seq was performed to observe gene expression alteration related to starch metabolism genes throughout the maturity stages of oil palm fruit with different oil yields. Gene expression profiles were examined with three different oil yields group (low, medium, and high) at six fruit development phases (4, 8, 12, 16, 20, and 22 weeks after pollination). We successfully identified and analyzed differentially expressed genes in oil palm mesocarps during development. The results showed that the transcriptome profile for each developmental phase was unique. Sucrose flux to the mesocarp tissue, rapid starch turnover, and high glycolytic activity have been identified as critical factors for oil production in oil palms. For starch metabolism and the glycolytic pathway, we identified specific gene expressions of enzyme isoforms (isozymes) that correlated with oil production, which may determine the oil content. This study provides valuable information for creating new high-oil-yielding palm varieties via breeding programs or genome editing approaches. KW - starch KW - oil yield KW - fruit development KW - gene expression KW - RNA-seq KW - and palm KW - oil KW - Elaeis guineensis Jacq Y1 - 2023 U6 - https://doi.org/10.3389/fpls.2023.1220237 SN - 1664-462X VL - 14 PB - Frontiers Media CY - Lausanne ER - TY - JOUR A1 - Apriyanto, Ardha A1 - Ajambang, Walter T1 - Transcriptomic dataset for early inflorescence stages of oil palm in response to defoliation stress JF - Data in Brief N2 - Oil palm breeding and seed development have been hindered due to the male parent's incapacity to produce male inflorescence as a source of pollen under normal conditions. On the other hand, a young oil palm plantation has a low pollination rate due to a lack of male flowers. These are the common problem of sex ratio in the oil palm industry. Nevertheless, the regulation of sex ratio in oil palm plants is a complex mechanism and remains an open question until now. Researchers have previously used complete defoliation to induce male inflorescences, but the biological and molecular mechanisms underlying this morphological change have yet to be discovered. Here, we present an RNA-seq dataset from three early stages of an oil palm inflorescence under normal conditions and complete defoliation stress. This transcriptomic dataset is a valuable resource to improve our understanding of sex determination mechanisms in oil palm inflorescence. KW - Complete defoliation KW - Flower development KW - Leaf axil KW - NGS KW - RNA-seq KW - Sex KW - determination Y1 - 2022 U6 - https://doi.org/10.1016/j.dib.2022.107914 SN - 2352-3409 VL - 41 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Giraudier, Manon A1 - Ventura-Bort, Carlos A1 - Weymar, Mathias T1 - Transcutaneous Vagus Nerve Stimulation (tVNS) Improves High-Confidence Recognition Memory but Not Emotional Word Processing JF - Frontiers in Psychology N2 - Previous clinical research found that invasive vagus nerve stimulation (VNS) enhanced word recognition memory in epileptic patients, an effect assumed to be related to the activation of brainstem arousal systems. In this study, we applied non-invasive transcutaneous auricular VNS (tVNS) to replicate and extend the previous work. Using a single-blind, randomized, between-subject design, 60 healthy volunteers received active or sham stimulation during a lexical decision task, in which emotional and neutral stimuli were classified as words or non-words. In a subsequent recognition memory task (1 day after stimulation), participants' memory performance on these words and their subjective memory confidence were tested. Salivary alpha-amylase (sAA) levels, a putative indirect measure of central noradrenergic activation, were also measured before and after stimulation. During encoding, pleasant words were more accurately detected than neutral and unpleasant words. However, no tVNS effects were observed on task performance or on overall sAA level changes. tVNS also did not modulate overall recognition memory, which was particularly enhanced for pleasant emotional words. However, when hit rates were split based on confidence ratings reflecting familiarity- and recollection-based memory, higher recollection-based memory performance (irrespective of emotional category) was observed during active stimulation than during sham stimulation. To summarize, we replicated prior findings of enhanced processing and memory for emotional (pleasant) words. Whereas tVNS showed no effects on word processing, subtle effects on recollection-based memory performance emerged, which may indicate that tVNS facilitates hippocampus-mediated consolidation processes. KW - transcutaneous vagus nerve stimulation KW - salivary alpha-amylase KW - emotion KW - words KW - episodic memory KW - recognition KW - recollection KW - confidence Y1 - 2020 U6 - https://doi.org/10.3389/fpsyg.2020.01276 SN - 1664-1078 VL - 11 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Seleem, Omar A1 - Ayzel, Georgy A1 - Bronstert, Axel A1 - Heistermann, Maik T1 - Transferability of data-driven models to predict urban pluvial flood water depth in Berlin, Germany JF - Natural Hazards and Earth System Sciences N2 - Data-driven models have been recently suggested to surrogate computationally expensive hydrodynamic models to map flood hazards. However, most studies focused on developing models for the same area or the same precipitation event. It is thus not obvious how transferable the models are in space. This study evaluates the performance of a convolutional neural network (CNN) based on the U-Net architecture and the random forest (RF) algorithm to predict flood water depth, the models' transferability in space and performance improvement using transfer learning techniques. We used three study areas in Berlin to train, validate and test the models. The results showed that (1) the RF models outperformed the CNN models for predictions within the training domain, presumable at the cost of overfitting; (2) the CNN models had significantly higher potential than the RF models to generalize beyond the training domain; and (3) the CNN models could better benefit from transfer learning technique to boost their performance outside training domains than RF models. Y1 - 2023 U6 - https://doi.org/10.5194/nhess-23-809-2023 SN - 1684-9981 SN - 1561-8633 VL - 23 IS - 2 SP - 809 EP - 822 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Leimkühler, Silke T1 - Transition metals in catalysis BT - the functional relationship of Fe-S clusters and molybdenum or tungsten cofactor-containing enzyme systems JF - Inorganics : open access journal Y1 - 2021 U6 - https://doi.org/10.3390/inorganics9010006 SN - 2304-6740 VL - 9 IS - 1 PB - MDPI CY - Basel ER - TY - JOUR A1 - Pikovskij, Arkadij T1 - Transition to synchrony in chiral active particles JF - Journal of physics. Complexity N2 - I study deterministic dynamics of chiral active particles in two dimensions. Particles are considered as discs interacting with elastic repulsive forces. An ensemble of particles, started from random initial conditions, demonstrates chaotic collisions resulting in their normal diffusion. This chaos is transient, as rather abruptly a synchronous collisionless state establishes. The life time of chaos grows exponentially with the number of particles. External forcing (periodic or chaotic) is shown to facilitate the synchronization transition. KW - active particles KW - chirality KW - synchronization KW - chaos KW - transient chaos Y1 - 2021 U6 - https://doi.org/10.1088/2632-072X/abdadb SN - 2632-072X VL - 2 IS - 2 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Kernecker, Maria A1 - Fienitz, Meike A1 - Nendel, Claas A1 - Paetzig, Marlene A1 - Walzl, Karin Pirhofer A1 - Raatz, Larissa A1 - Schmidt, Martin A1 - Wulf, Monika A1 - Zscheischler, Jana T1 - Transition zones across agricultural field boundaries for integrated landscape research and management of biodiversity and yields JF - Ecological solutions and evidence N2 - Biodiversity conservation and agricultural production have been largely framed as separate goals for landscapes in the discourse on land use. Although there is an increasing tendency to move away from this dichotomy in theory, the tendency is perpetuated by the spatially explicit approaches used in research and management practice. Transition zones (TZ) have previously been defined as areas where two adjacent fields or patches interact, and so they occur abundantly throughout agricultural landscapes. Biodiversity patterns in TZ have been extensively studied, but their relationship to yield patterns and social-ecological dimensions has been largely neglected. Focusing on European, temperate agricultural landscapes, we outline three areas of research and management that together demonstrate how TZ might be used to facilitate an integrated landscape approach: (i) plant and animal species' use and response to boundaries and the resulting effects on yield, for a deeper understanding of how landscape structure shapes quantity and quality of TZ; (ii) local knowledge on field or patch-level management and its interactions with biodiversity and yield in TZ, and (iii) conflict prevention and collaborative management across land-use boundaries. KW - ecotones KW - field boundaries KW - functional traits KW - landscape complexity; KW - land-use conflicts KW - local knowledge KW - spillovers Y1 - 2022 U6 - https://doi.org/10.1002/2688-8319.12122 SN - 2688-8319 VL - 3 IS - 1 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Naïr, Alexandra A1 - Lin, Chiao-I A1 - Wippert, Pia-Maria T1 - Translation and adaptation of the French version of the risk stratification index, a tool for stratified care in chronic low back pain BT - A pilot study JF - Medicina : monthly medical journal of Lithuanian Medical Association, Kaunas N2 - Background and Objectives: Low back pain is a worldwide health problem. An early diagnosis is required to develop personalized treatment strategies. The Risk Stratification Index (RSI) was developed to serve the purpose. The aim of this pilot study is to cross-culturally translate the RSI to a French version (RSI-F) and evaluate the test-retest reliability of RSI-F using a French active population. Materials and Methods: The RSI was translated from German to French (RSI-F) based on the guidelines of cross-cultural adaptation of self-report measures. A total of 42 French recreational athletes (age 18–63 years) with non-specific low back pain were recruited and filled in the RSI-F twice. The test-retest reliability was examined using intraclass correlation coefficient (ICC1,2) and Pearson correlation coefficient. Results: Finally, 33 questionnaires were analyzed (14 males and 19 females, age 31 ± 10 years, 9.5 ± 3.2 h/week of training). The test-retest of RSI-F CPI and DISS were excellent (CPI: ICC1,2 = 0.989, p < 0.001; r = 0.989, p < 0.001; DISS: ICC1,2 = 0.991, p < 0.001; r = 0.991, p < 0.001), as well as Korff pain intensity (ICC1,2 = 0.995, p < 0.001; r = 0.995, p < 0.001) and disability (ICC1,2 = 0.998, p < 0.001; r = 0.998, p < 0.001). Conclusion: The RSI-F is linguistically accurate and reliable for use by a French-speaking active population with non-specific low back pain. The RSI-F is considered a tool to examine the evolution of psychosocial factors and therefore the risk of chronicity and the prognostic of pain. Further evaluations, such as internal, external validity, and responsiveness should be evaluated in a larger population. KW - RSI KW - translation-reliability KW - back-pain screening KW - yellow flags KW - psychosocial moderators Y1 - 2022 U6 - https://doi.org/10.3390/medicina58040469 SN - 1648-9144 VL - 58 IS - 4 SP - 1 EP - 8 PB - Kaunas Univ. of Medicine CY - Kaunas, Litauen ER - TY - JOUR A1 - Wicha, Sebastian G. A1 - Huisinga, Wilhelm A1 - Kloft, Charlotte T1 - Translational pharmacometric evaluation of typical antibiotic broad-spectrum combination therapies against staphylococcus aureus exploiting in vitro information JF - CPT: pharmacometrics & systems pharmacology N2 - Broad-spectrum antibiotic combination therapy is frequently applied due to increasing resistance development of infective pathogens. The objective of the present study was to evaluate two common empiric broad-spectrum combination therapies consisting of either linezolid (LZD) or vancomycin (VAN) combined with meropenem (MER) against Staphylococcus aureus (S. aureus) as the most frequent causative pathogen of severe infections. A semimechanistic pharmacokinetic-pharmacodynamic (PK-PD) model mimicking a simplified bacterial life-cycle of S. aureus was developed upon time-kill curve data to describe the effects of LZD, VAN, and MER alone and in dual combinations. The PK-PD model was successfully (i) evaluated with external data from two clinical S. aureus isolates and further drug combinations and (ii) challenged to predict common clinical PK-PD indices and breakpoints. Finally, clinical trial simulations were performed that revealed that the combination of VAN-MER might be favorable over LZD-MER due to an unfavorable antagonistic interaction between LZD and MER. Y1 - 2017 U6 - https://doi.org/10.1002/psp4.12197 SN - 2163-8306 VL - 6 SP - 512 EP - 522 PB - Wiley CY - Hoboken ER - TY - GEN T1 - Transnational American Jewish Studies BT - A Select Bibliography T2 - PaRDeS : Journal of the Association for Jewish Studies in Germany T2 - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-537525 SN - 978-3-86956-520-0 SN - 1614-6492 SN - 1862-7684 IS - 27 SP - 143 EP - 147 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Bethge, Joseph A1 - Serth, Sebastian A1 - Staubitz, Thomas A1 - Wuttke, Tobias A1 - Nordemann, Oliver A1 - Das, Partha-Pratim A1 - Meinel, Christoph T1 - TransPipe BT - A Pipeline for Automated Transcription and Translation of Videos JF - EMOOCs 2021 N2 - Online learning environments, such as Massive Open Online Courses (MOOCs), often rely on videos as a major component to convey knowledge. However, these videos exclude potential participants who do not understand the lecturer’s language, regardless of whether that is due to language unfamiliarity or aural handicaps. Subtitles and/or interactive transcripts solve this issue, ease navigation based on the content, and enable indexing and retrieval by search engines. Although there are several automated speech-to-text converters and translation tools, their quality varies and the process of integrating them can be quite tedious. Thus, in practice, many videos on MOOC platforms only receive subtitles after the course is already finished (if at all) due to a lack of resources. This work describes an approach to tackle this issue by providing a dedicated tool, which is closing this gap between MOOC platforms and transcription and translation tools and offering a simple workflow that can easily be handled by users with a less technical background. The proposed method is designed and evaluated by qualitative interviews with three major MOOC providers. Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-516943 VL - 2021 SP - 79 EP - 94 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Burek, Wojciech T1 - Treaty flexibility unilaterally boosted BT - reservations to European social charters JF - Netherlands quarterly of human rights N2 - Thus far, research into reservations to treaties has often overlooked reservations formulated to both European Social Charters (and its Protocols) and the relevant European Committee of Social Rights practices. There are several pressing reasons to further explore this gap in existing literature. First, an analysis of practices within the European Social Charters (and Protocols) will provide a fuller picture of the reservations and responses of treaty bodies. Second, in the context of previous landmark events it is worth noting the practices of another human rights treaty monitoring body that is often omitted from analyses. Third, the very fact that the formulation of reservations to treaties gives parties such far-reaching flexibility to shape their contractual obligations (à la carte) is surprising. An important outcome of the research is the finding that, despite the far-reaching flexibility present in the treaties analysed, both the States Parties and the European Committee of Social Rights generally treat them as conventional treaties to which the general rules on reservations apply. Consequently, there is no basis for assuming that the mere fact of adopting the à la carte system in a treaty with no reservation clause implies a formal prohibition of reservations or otherwise discourages their formulation. Y1 - 2023 U6 - https://doi.org/10.1177/09240519231151950 SN - 0924-0519 SN - 2214-7357 VL - 41 IS - 1 SP - 35 EP - 52 PB - Sage Publications Ltd CY - London ER - TY - JOUR A1 - Deusdará-Leal, Karinne A1 - Samprogna Mohor, Guilherme A1 - Cuartas, Luz Adriana A1 - Seluchi, Marcelo E. A1 - Marengo, Jose A. A1 - Zhang, Rong A1 - Broedel, Elisangela A1 - Amore, Diogo de Jesus A1 - Alvalá, Regina C. S. A1 - Cunha, Ana Paula M. A. A1 - Gonçalves, José A. C. T1 - Trends and climate elasticity of streamflow in south-eastern Brazil basins JF - Water N2 - Trends in streamflow, rainfall and potential evapotranspiration (PET) time series, from 1970 to 2017, were assessed for five important hydrological basins in Southeastern Brazil. The concept of elasticity was also used to assess the streamflow sensitivity to changes in climate variables, for annual data and 5-, 10- and 20-year moving averages. Significant negative trends in streamflow and rainfall and significant increasing trend in PET were detected. For annual analysis, elasticity revealed that 1% decrease in rainfall resulted in 1.21-2.19% decrease in streamflow, while 1% increase in PET induced different reductions percentages in streamflow, ranging from 2.45% to 9.67%. When both PET and rainfall were computed to calculate the elasticity, results were positive for some basins. Elasticity analysis considering 20-year moving averages revealed that impacts on the streamflow were cumulative: 1% decrease in rainfall resulted in 1.83-4.75% decrease in streamflow, while 1% increase in PET induced 3.47-28.3% decrease in streamflow. This different temporal response may be associated with the hydrological memory of the basins. Streamflow appears to be more sensitive in less rainy basins. This study provides useful information to support strategic government decisions, especially when the security of water resources and drought mitigation are considered in face of climate change. KW - runoff KW - precipitation KW - potential evapotranspiration KW - Pettitt test KW - sensitivity Y1 - 2022 U6 - https://doi.org/10.3390/w14142245 SN - 2073-4441 VL - 14 IS - 14 PB - MDPI CY - Basel ER - TY - JOUR A1 - Veh, Georg A1 - Lützow, Natalie A1 - Kharlamova, Varvara A1 - Petrakov, Dmitry A1 - Hugonnet, Romain A1 - Korup, Oliver T1 - Trends, breaks, and biases in the frequency of reported glacier lake outburst floods JF - Earth's future N2 - Thousands of glacier lakes have been forming behind natural dams in high mountains following glacier retreat since the early 20th century. Some of these lakes abruptly released pulses of water and sediment with disastrous downstream consequences. Yet it remains unclear whether the reported rise of these glacier lake outburst floods (GLOFs) has been fueled by a warming atmosphere and enhanced meltwater production, or simply a growing research effort. Here we estimate trends and biases in GLOF reporting based on the largest global catalog of 1,997 dated glacier-related floods in six major mountain ranges from 1901 to 2017. We find that the positive trend in the number of reported GLOFs has decayed distinctly after a break in the 1970s, coinciding with independently detected trend changes in annual air temperatures and in the annual number of field-based glacier surveys (a proxy of scientific reporting). We observe that GLOF reports and glacier surveys decelerated, while temperature rise accelerated in the past five decades. Enhanced warming alone can thus hardly explain the annual number of reported GLOFs, suggesting that temperature-driven glacier lake formation, growth, and failure are weakly coupled, or that outbursts have been overlooked. Indeed, our analysis emphasizes a distinct geographic and temporal bias in GLOF reporting, and we project that between two to four out of five GLOFs on average might have gone unnoticed in the early to mid-20th century. We recommend that such biases should be considered, or better corrected for, when attributing the frequency of reported GLOFs to atmospheric warming. KW - glaciers KW - climate change KW - hazard KW - mountains KW - cryosphere KW - frequency Y1 - 2022 U6 - https://doi.org/10.1029/2021EF002426 SN - 2328-4277 VL - 10 IS - 3 PB - American Geophysical Union CY - Washington ER - TY - JOUR A1 - Veh, Georg A1 - Lützow, Natalie A1 - Kharlamova, Varvara A1 - Petrakov, Dmitry A1 - Hugonnet, Romain A1 - Korup, Oliver T1 - Trends, Breaks, and Biases in the Frequency of Reported Glacier Lake Outburst Floods JF - Earth's Future N2 - Thousands of glacier lakes have been forming behind natural dams in high mountains following glacier retreat since the early 20th century. Some of these lakes abruptly released pulses of water and sediment with disastrous downstream consequences. Yet it remains unclear whether the reported rise of these glacier lake outburst floods (GLOFs) has been fueled by a warming atmosphere and enhanced meltwater production, or simply a growing research effort. Here we estimate trends and biases in GLOF reporting based on the largest global catalog of 1,997 dated glacier-related floods in six major mountain ranges from 1901 to 2017. We find that the positive trend in the number of reported GLOFs has decayed distinctly after a break in the 1970s, coinciding with independently detected trend changes in annual air temperatures and in the annual number of field-based glacier surveys (a proxy of scientific reporting). We observe that GLOF reports and glacier surveys decelerated, while temperature rise accelerated in the past five decades. Enhanced warming alone can thus hardly explain the annual number of reported GLOFs, suggesting that temperature-driven glacier lake formation, growth, and failure are weakly coupled, or that outbursts have been overlooked. Indeed, our analysis emphasizes a distinct geographic and temporal bias in GLOF reporting, and we project that between two to four out of five GLOFs on average might have gone unnoticed in the early to mid-20th century. We recommend that such biases should be considered, or better corrected for, when attributing the frequency of reported GLOFs to atmospheric warming. Y1 - 2022 U6 - https://doi.org/10.1029/2021EF002426 SN - 2328-4277 VL - 10 SP - 1 EP - 14 PB - Wiley-Blackwell CY - Hoboken, New Jersey ET - 3 ER - TY - BOOK A1 - Barkowsky, Matthias A1 - Giese, Holger T1 - Triple graph grammars for multi-version models N2 - Like conventional software projects, projects in model-driven software engineering require adequate management of multiple versions of development artifacts, importantly allowing living with temporary inconsistencies. In the case of model-driven software engineering, employed versioning approaches also have to handle situations where different artifacts, that is, different models, are linked via automatic model transformations. In this report, we propose a technique for jointly handling the transformation of multiple versions of a source model into corresponding versions of a target model, which enables the use of a more compact representation that may afford improved execution time of both the transformation and further analysis operations. Our approach is based on the well-known formalism of triple graph grammars and a previously introduced encoding of model version histories called multi-version models. In addition to showing the correctness of our approach with respect to the standard semantics of triple graph grammars, we conduct an empirical evaluation that demonstrates the potential benefit regarding execution time performance. N2 - Ähnlich zu konventionellen Softwareprojekten erfordern Projekte im Bereich der modellgetriebenen Softwareentwicklung eine adäquate Verwaltung mehrerer Versionen von Entwicklungsartefakten. Eine solche Versionsverwaltung muss es insbesondere ermöglichen, zeitweise mit Inkonsistenzen zu leben. Im Fall der modellgetriebenen Softwareentwicklung muss ein verwendeter Ansatz zusätzlich mit Situationen umgehen können, in denen verschiedene Entwicklungsartefakte, das heißt verschiedene Modelle, durch automatische Modelltransformationen verknüpft sind. In diesem Bericht schlagen wir eine Technik für die integrierte Transformation mehrerer Versionen eines Quellmodells in entsprechende Versionen eines Zielmodells vor. Dies ermöglicht die Verwendung einer kompakteren Repräsentation der Modelle, was zu verbesserten Laufzeiteigenschaften der Transformation und weiterführender Operationen führen kann. Unser Ansatz basiert auf dem bekannten Formalismus der Tripel-Graph-Grammatiken und einer in früheren Arbeiten eingeführten Kodierung von Versionshistorien von Modellen. Neben einem Beweis der Korrektheit des Ansatzes in Bezug auf die standardmäßige Semantik von Tripel-Graph-Grammatiken führen wir eine empirische Evaluierung durch, die den potenziellen Performancevorteil der Technik demonstriert. T3 - Technische Berichte des Hasso-Plattner-Instituts für Digital Engineering an der Universität Potsdam - 155 KW - triple graph grammars KW - multi-version models KW - Tripel-Graph-Grammatiken KW - Modelle mit mehreren Versionen Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-573994 SN - 978-3-86956-556-9 SN - 1613-5652 SN - 2191-1665 IS - 155 SP - 28 EP - 28 ER - TY - JOUR A1 - Kaech, Heidi A1 - Dennis, Alice B. A1 - Vorburger, Christoph T1 - Triple RNA-Seq characterizes aphid gene expression in response to infection with unequally virulent strains of the endosymbiont Hamiltonella defensa JF - BMC genomics N2 - Background Secondary endosymbionts of aphids provide benefits to their hosts, but also impose costs such as reduced lifespan and reproductive output. The aphid Aphis fabae is host to different strains of the secondary endosymbiont Hamiltonella defensa, which encode different putative toxins. These strains have very different phenotypes: They reach different densities in the host, and the costs and benefits (protection against parasitoid wasps) they confer to the host vary strongly. Results We used RNA-Seq to generate hypotheses on why four of these strains inflict such different costs to A. fabae. We found different H. defensa strains to cause strain-specific changes in aphid gene expression, but little effect of H. defensa on gene expression of the primary endosymbiont, Buchnera aphidicola. The highly costly and over-replicating H. defensa strain H85 was associated with strongly reduced aphid expression of hemocytin, a marker of hemocytes in Drosophila. The closely related strain H15 was associated with downregulation of ubiquitin-related modifier 1, which is related to nutrient-sensing and oxidative stress in other organisms. Strain H402 was associated with strong differential regulation of a set of hypothetical proteins, the majority of which were only differentially regulated in presence of H402. Conclusions Overall, our results suggest that costs of different strains of H. defensa are likely caused by different mechanisms, and that these costs are imposed by interacting with the host rather than the host's obligatory endosymbiont B. aphidicola. KW - Aphis fabae KW - Buchnera KW - Cost of resistance KW - Hamiltonella KW - Host-symbiont interaction KW - RNA-Seq KW - Symbiosis Y1 - 2021 U6 - https://doi.org/10.1186/s12864-021-07742-8 SN - 1471-2164 VL - 22 IS - 1 PB - BioMed Central CY - London ER - TY - JOUR A1 - Trautmann, Justin A1 - Zhou, Lin A1 - Brahms, Clemens Markus A1 - Tunca, Can A1 - Ersoy, Cem A1 - Granacher, Urs A1 - Arnrich, Bert T1 - TRIPOD BT - A treadmill walking dataset with IMU, pressure-distribution and photoelectric data for gait analysis JF - Data : open access ʻData in scienceʼ journal N2 - Inertial measurement units (IMUs) enable easy to operate and low-cost data recording for gait analysis. When combined with treadmill walking, a large number of steps can be collected in a controlled environment without the need of a dedicated gait analysis laboratory. In order to evaluate existing and novel IMU-based gait analysis algorithms for treadmill walking, a reference dataset that includes IMU data as well as reliable ground truth measurements for multiple participants and walking speeds is needed. This article provides a reference dataset consisting of 15 healthy young adults who walked on a treadmill at three different speeds. Data were acquired using seven IMUs placed on the lower body, two different reference systems (Zebris FDMT-HQ and OptoGait), and two RGB cameras. Additionally, in order to validate an existing IMU-based gait analysis algorithm using the dataset, an adaptable modular data analysis pipeline was built. Our results show agreement between the pressure-sensitive Zebris and the photoelectric OptoGait system (r = 0.99), demonstrating the quality of our reference data. As a use case, the performance of an algorithm originally designed for overground walking was tested on treadmill data using the data pipeline. The accuracy of stride length and stride time estimations was comparable to that reported in other studies with overground data, indicating that the algorithm is equally applicable to treadmill data. The Python source code of the data pipeline is publicly available, and the dataset will be provided by the authors upon request, enabling future evaluations of IMU gait analysis algorithms without the need of recording new data. KW - inertial measurement unit KW - gait analysis algorithm KW - OptoGait KW - Zebris KW - data pipeline KW - public dataset Y1 - 2021 U6 - https://doi.org/10.3390/data6090095 SN - 2306-5729 VL - 6 IS - 9 PB - MDPI CY - Basel ER - TY - JOUR A1 - Hodgkins, Suzanne B. A1 - Richardson, Curtis J. A1 - Dommain, Rene A1 - Wang, Hongjun A1 - Glaser, Paul H. A1 - Verbeke, Brittany A1 - Winkler, B. Rose A1 - Cobb, Alexander R. A1 - Rich, Virginia I. A1 - Missilmani, Malak A1 - Flanagan, Neal A1 - Ho, Mengchi A1 - Hoyt, Alison M. A1 - Harvey, Charles F. A1 - Vining, S. Rose A1 - Hough, Moira A. A1 - Moore, Tim R. A1 - Richard, Pierre J. H. A1 - De la Cruz, Florentino B. A1 - Toufaily, Joumana A1 - Hamdan, Rasha A1 - Cooper, William T. A1 - Chanton, Jeffrey P. T1 - Tropical peatland carbon storage linked to global latitudinal trends in peat recalcitrance JF - Nature Communications N2 - Peatlands represent large terrestrial carbon banks. Given that most peat accumulates in boreal regions, where low temperatures and water saturation preserve organic matter, the existence of peat in (sub)tropical regions remains enigmatic. Here we examined peat and plant chemistry across a latitudinal transect from the Arctic to the tropics. Near-surface low-latitude peat has lower carbohydrate and greater aromatic content than near-surface high-latitude peat, creating a reduced oxidation state and resulting recalcitrance. This recalcitrance allows peat to persist in the (sub)tropics despite warm temperatures. Because we observed similar declines in carbohydrate content with depth in high-latitude peat, our data explain recent field-scale deep peat warming experiments in which catotelm (deeper) peat remained stable despite temperature increases up to 9 degrees C. We suggest that high-latitude deep peat reservoirs may be stabilized in the face of climate change by their ultimately lower carbohydrate and higher aromatic composition, similar to tropical peats. Y1 - 2018 U6 - https://doi.org/10.1038/s41467-018-06050-2 SN - 2041-1723 VL - 9 PB - Nature Publ. Group CY - London ER - TY - JOUR A1 - Zagrebnov, Valentin T1 - Trotter product formula on Hilbert and Banach spaces for operator-norm convergence JF - Lectures in pure and applied mathematics KW - random point processes KW - statistical mechanics KW - stochastic analysis Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-471971 SN - 978-3-86956-485-2 SN - 2199-4951 SN - 2199-496X SP - 23 EP - 34 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Petreska, Irina A1 - Pejov, Ljupco A1 - Sandev, Trifce A1 - Kocarev, Ljupčo A1 - Metzler, Ralf T1 - Tuning of the dielectric relaxation and complex susceptibility in a system of polar molecules: a generalised model based on rotational diffusion with resetting JF - Fractal and fractional N2 - The application of the fractional calculus in the mathematical modelling of relaxation processes in complex heterogeneous media has attracted a considerable amount of interest lately. The reason for this is the successful implementation of fractional stochastic and kinetic equations in the studies of non-Debye relaxation. In this work, we consider the rotational diffusion equation with a generalised memory kernel in the context of dielectric relaxation processes in a medium composed of polar molecules. We give an overview of existing models on non-exponential relaxation and introduce an exponential resetting dynamic in the corresponding process. The autocorrelation function and complex susceptibility are analysed in detail. We show that stochastic resetting leads to a saturation of the autocorrelation function to a constant value, in contrast to the case without resetting, for which it decays to zero. The behaviour of the autocorrelation function, as well as the complex susceptibility in the presence of resetting, confirms that the dielectric relaxation dynamics can be tuned by an appropriate choice of the resetting rate. The presented results are general and flexible, and they will be of interest for the theoretical description of non-trivial relaxation dynamics in heterogeneous systems composed of polar molecules. KW - rotational diffusion KW - memory kernel KW - Fokker-Planck equation KW - non-exponential relaxation KW - autocorrelation function KW - complex KW - susceptibility Y1 - 2022 U6 - https://doi.org/10.3390/fractalfract6020088 SN - 2504-3110 VL - 6 IS - 2 PB - MDPI AG, Fractal Fract Editorial Office CY - Basel ER - TY - JOUR A1 - Bruckmaier, Georg A1 - Krauss, Stefan A1 - Binder, Karin A1 - Hilbert, Sven Lars A1 - Brunner, Martin T1 - Tversky and Kahneman’s cognitive illusions BT - who can solve them, and why? JF - Frontiers in psychology N2 - In the present paper we empirically investigate the psychometric properties of some of the most famous statistical and logical cognitive illusions from the "heuristics and biases" research program by Daniel Kahneman and Amos Tversky, who nearly 50 years ago introduced fascinating brain teasers such as the famous Linda problem, the Wason card selection task, and so-called Bayesian reasoning problems (e.g., the mammography task). In the meantime, a great number of articles has been published that empirically examine single cognitive illusions, theoretically explaining people's faulty thinking, or proposing and experimentally implementing measures to foster insight and to make these problems accessible to the human mind. Yet these problems have thus far usually been empirically analyzed on an individual-item level only (e.g., by experimentally comparing participants' performance on various versions of one of these problems). In this paper, by contrast, we examine these illusions as a group and look at the ability to solve them as a psychological construct. Based on an sample of N = 2,643 Luxembourgian school students of age 16-18 we investigate the internal psychometric structure of these illusions (i.e., Are they substantially correlated? Do they form a reflexive or a formative construct?), their connection to related constructs (e.g., Are they distinguishable from intelligence or mathematical competence in a confirmatory factor analysis?), and the question of which of a person's abilities can predict the correct solution of these brain teasers (by means of a regression analysis). KW - statistical reasoning KW - logical thinking KW - cognitive illusion KW - Monty Hall KW - problem KW - Wason task KW - Linda problem KW - hospital problem KW - Bayesian reasoning Y1 - 2021 U6 - https://doi.org/10.3389/fpsyg.2021.584689 SN - 1664-1078 VL - 12 PB - Frontiers Research Foundation CY - Lausanne ER - TY - GEN A1 - Jauer, Nora T1 - Two milestones in favour of the environment in just a few days? Y1 - 2021 UR - https://voelkerrechtsblog.org/two-milestones-in-favour-of-the-environment-in-just-a-few-days/ U6 - https://doi.org/10.17176/20211102-172527-0 SN - 2510-2567 PB - M. Riegner c/o Humboldt-Univ. CY - Berlin ER - TY - JOUR A1 - Démaris, Alix A1 - Widigson, Ella S. K. A1 - Ilvemark, Johan F. K. F. A1 - Steenholdt, Casper A1 - Seidelin, Jakob B. A1 - Huisinga, Wilhelm A1 - Michelet, Robin A1 - Aulin, Linda B. S. A1 - Kloft, Charlotte T1 - Ulcerative colitis and acute severe ulcerative colitis patients are overlooked in infliximab population pharmacokinetic models BT - results from a comprehensive review JF - Pharmaceutics / Molecular Diversity Preservation International N2 - Ulcerative colitis (UC) is part of the inflammatory bowels diseases, and moderate to severe UC patients can be treated with anti-tumour necrosis alpha monoclonal antibodies, including infliximab (IFX). Even though treatment of UC patients by IFX has been in place for over a decade, many gaps in modelling of IFX PK in this population remain. This is even more true for acute severe UC (ASUC) patients for which early prediction of IFX pharmacokinetic (PK) could highly improve treatment outcome. Thus, this review aims to compile and analyse published population PK models of IFX in UC and ASUC patients, and to assess the current knowledge on disease activity impact on IFX PK. For this, a semi-systematic literature search was conducted, from which 26 publications including a population PK model analysis of UC patients receiving IFX therapy were selected. Amongst those, only four developed a model specifically for UC patients, and only three populations included severe UC patients. Investigations of disease activity impact on PK were reported in only 4 of the 14 models selected. In addition, the lack of reported model codes and assessment of predictive performance make the use of published models in a clinical setting challenging. Thus, more comprehensive investigation of PK in UC and ASUC is needed as well as more adequate reports on developed models and their evaluation in order to apply them in a clinical setting. KW - infliximab KW - inflammatory bowel disease KW - ulcerative colitis KW - acute severe KW - disease activity KW - pharmacokinetic KW - pharmacometrics Y1 - 2022 U6 - https://doi.org/10.3390/pharmaceutics14102095 SN - 1999-4923 VL - 14 IS - 10 PB - MDPI CY - Basel ER - TY - JOUR A1 - Kamali, Bahareh A1 - Lorite, Ignacio J. A1 - Webber, Heidi A. A1 - Rezaei, Ehsan Eyshi A1 - Gabaldon-Leal, Clara A1 - Nendel, Claas A1 - Siebert, Stefan A1 - Ramirez-Cuesta, Juan Miguel A1 - Ewert, Frank A1 - Ojeda, Jonathan J. T1 - Uncertainty in climate change impact studies for irrigated maize cropping systems in southern Spain JF - Scientific reports N2 - This study investigates the main drivers of uncertainties in simulated irrigated maize yield under historical conditions as well as scenarios of increased temperatures and altered irrigation water availability. Using APSIM, MONICA, and SIMPLACE crop models, we quantified the relative contributions of three irrigation water allocation strategies, three sowing dates, and three maize cultivars to the uncertainty in simulated yields. The water allocation strategies were derived from historical records of farmer's allocation patterns in drip-irrigation scheme of the Genil-Cabra region, Spain (2014-2017). By considering combinations of allocation strategies, the adjusted R-2 values (showing the degree of agreement between simulated and observed yields) increased by 29% compared to unrealistic assumptions of considering only near optimal or deficit irrigation scheduling. The factor decomposition analysis based on historic climate showed that irrigation strategies was the main driver of uncertainty in simulated yields (66%). However, under temperature increase scenarios, the contribution of crop model and cultivar choice to uncertainty in simulated yields were as important as irrigation strategy. This was partially due to different model structure in processes related to the temperature responses. Our study calls for including information on irrigation strategies conducted by farmers to reduce the uncertainty in simulated yields at field scale. Y1 - 2022 U6 - https://doi.org/10.1038/s41598-022-08056-9 SN - 2045-2322 VL - 12 IS - 1 PB - Macmillan Publishers Limited, CY - London ER - TY - JOUR A1 - Devitt, Laura A1 - Neal, Jeffrey A1 - Wagener, Thorsten A1 - Coxon, Gemma T1 - Uncertainty in the extreme flood magnitude estimates of large-scale flood hazard models JF - Environmental research letters : ERL / Institute of Physics N2 - The growing worldwide impact of flood events has motivated the development and application of global flood hazard models (GFHMs). These models have become useful tools for flood risk assessment and management, especially in regions where little local hazard information is available. One of the key uncertainties associated with GFHMs is the estimation of extreme flood magnitudes to generate flood hazard maps. In this study, the 1-in-100 year flood (Q100) magnitude was estimated using flow outputs from four global hydrological models (GHMs) and two global flood frequency analysis datasets for 1350 gauges across the conterminous US. The annual maximum flows of the observed and modelled timeseries of streamflow were bootstrapped to evaluate the sensitivity of the underlying data to extrapolation. Results show that there are clear spatial patterns of bias associated with each method. GHMs show a general tendency to overpredict Western US gauges and underpredict Eastern US gauges. The GloFAS and HYPE models underpredict Q100 by more than 25% in 68% and 52% of gauges, respectively. The PCR-GLOBWB and CaMa-Flood models overestimate Q100 by more than 25% at 60% and 65% of gauges in West and Central US, respectively. The global frequency analysis datasets have spatial variabilities that differ from the GHMs. We found that river basin area and topographic elevation explain some of the spatial variability in predictive performance found in this study. However, there is no single model or method that performs best everywhere, and therefore we recommend a weighted ensemble of predictions of extreme flood magnitudes should be used for large-scale flood hazard assessment. KW - large-scale flood hazard models KW - global hydrological model KW - flood risk Y1 - 2021 U6 - https://doi.org/10.1088/1748-9326/abfac4 SN - 1748-9326 VL - 16 IS - 6 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Stone, Kate A1 - Nicenboim, Bruno A1 - Vasishth, Shravan A1 - Rösler, Frank T1 - Understanding the effects of constraint and predictability in ERP JF - Neurobiology of language N2 - Intuitively, strongly constraining contexts should lead to stronger probabilistic representations of sentences in memory. Encountering unexpected words could therefore be expected to trigger costlier shifts in these representations than expected words. However, psycholinguistic measures commonly used to study probabilistic processing, such as the N400 event-related potential (ERP) component, are sensitive to word predictability but not to contextual constraint. Some research suggests that constraint-related processing cost may be measurable via an ERP positivity following the N400, known as the anterior post-N400 positivity (PNP). The PNP is argued to reflect update of a sentence representation and to be distinct from the posterior P600, which reflects conflict detection and reanalysis. However, constraint-related PNP findings are inconsistent. We sought to conceptually replicate Federmeier et al. (2007) and Kuperberg et al. (2020), who observed that the PNP, but not the N400 or the P600, was affected by constraint at unexpected but plausible words. Using a pre-registered design and statistical approach maximising power, we demonstrated a dissociated effect of predictability and constraint: strong evidence for predictability but not constraint in the N400 window, and strong evidence for constraint but not predictability in the later window. However, the constraint effect was consistent with a P600 and not a PNP, suggesting increased conflict between a strong representation and unexpected input rather than greater update of the representation. We conclude that either a simple strong/weak constraint design is not always sufficient to elicit the PNP, or that previous PNP constraint findings could be an artifact of smaller sample size. KW - N400 KW - anterior PNP KW - posterior P600 KW - probabilistic processing KW - constraint KW - predictability KW - entropy Y1 - 2022 U6 - https://doi.org/10.1162/nol_a_00094 SN - 2641-4368 VL - 4 IS - 2 SP - 221 EP - 256 PB - MIT Press CY - Cambridge, MA, USA ER - TY - JOUR A1 - Trouwloon, Danick A1 - Streck, Charlotte A1 - Chagas, Thiago A1 - Martinus, Glenpherd T1 - Understanding the use of carbon credits by companies BT - a review of the defining elements of corporate climate claims JF - Global challenges (Hoboken, NJ) N2 - Worldwide, companies are increasingly making claims about their current climate efforts and their future mitigation commitments. These claims tend to be underpinned by carbon credits issued in voluntary carbon markets to offset emissions. Corporate climate claims are largely unregulated which means that they are often (perceived to be) misleading and deceptive. As such, corporate climate claims risk undermining, rather than contributing to, global climate mitigation. This paper takes as its point of departure the proposition that a better understanding of corporate climate claims is needed to govern such claims in a manner that adequately addresses potential greenwashing risks. To that end, the paper reviews the nascent literature on corporate climate claims relying on the use of voluntary carbon credits. Drawing on the reviewed literature, three key dimensions of corporate climate claims as related to carbon credits are discussed: 1) the intended use of carbon credits: offsetting versus non-offsetting claims; 2) the framing and meaning of headline terms: net-zero versus carbon neutral claims; and 3) the status of the claim: future aspirational commitments versus stated achievements. The paper thereby offers a preliminary categorization of corporate climate claims and discusses risks associated with and governance implications for each of these categories. Y1 - 2023 U6 - https://doi.org/10.1002/gch2.202200158 SN - 2056-6646 VL - 7 IS - 4 PB - Wiley CY - Hoboken, NJ ER - TY - JOUR A1 - Frieler, Katja A1 - Schauberger, Bernhard A1 - Arneth, Almut A1 - Balkovic, Juraj A1 - Chryssanthacopoulos, James A1 - Deryng, Delphine A1 - Elliott, Joshua A1 - Folberth, Christian A1 - Khabarov, Nikolay A1 - Müller, Christoph A1 - Olin, Stefan A1 - Pugh, Thomas A. M. A1 - Schaphoff, Sibyll A1 - Schewe, Jacob A1 - Schmid, Erwin A1 - Warszawski, Lila A1 - Levermann, Anders T1 - Understanding the weather signal in national crop-yield variability JF - Earths future N2 - Year-to-year variations in crop yields can have major impacts on the livelihoods of subsistence farmers and may trigger significant global price fluctuations, with severe consequences for people in developing countries. Fluctuations can be induced by weather conditions, management decisions, weeds, diseases, and pests. Although an explicit quantification and deeper understanding of weather-induced crop-yield variability is essential for adaptation strategies, so far it has only been addressed by empirical models. Here, we provide conservative estimates of the fraction of reported national yield variabilities that can be attributed to weather by state-of-the-art, process-based crop model simulations. We find that observed weather variations can explain more than 50% of the variability in wheat yields in Australia, Canada, Spain, Hungary, and Romania. For maize, weather sensitivities exceed 50% in seven countries, including the United States. The explained variance exceeds 50% for rice in Japan and South Korea and for soy in Argentina. Avoiding water stress by simulating yields assuming full irrigation shows that water limitation is a major driver of the observed variations in most of these countries. Identifying the mechanisms leading to crop-yield fluctuations is not only fundamental for dampening fluctuations, but is also important in the context of the debate on the attribution of loss and damage to climate change. Since process-based crop models not only account for weather influences on crop yields, but also provide options to represent human-management measures, they could become essential tools for differentiating these drivers, and for exploring options to reduce future yield fluctuations. Y1 - 2017 U6 - https://doi.org/10.1002/2016EF000525 SN - 2328-4277 VL - 5 SP - 605 EP - 616 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Wang, Wei A1 - Seno, Flavio A1 - Sokolov, Igor M. A1 - Chechkin, Aleksei V. A1 - Metzler, Ralf T1 - Unexpected crossovers in correlated random-diffusivity processes JF - New Journal of Physics N2 - The passive and active motion of micron-sized tracer particles in crowded liquids and inside living biological cells is ubiquitously characterised by 'viscoelastic' anomalous diffusion, in which the increments of the motion feature long-ranged negative and positive correlations. While viscoelastic anomalous diffusion is typically modelled by a Gaussian process with correlated increments, so-called fractional Gaussian noise, an increasing number of systems are reported, in which viscoelastic anomalous diffusion is paired with non-Gaussian displacement distributions. Following recent advances in Brownian yet non-Gaussian diffusion we here introduce and discuss several possible versions of random-diffusivity models with long-ranged correlations. While all these models show a crossover from non-Gaussian to Gaussian distributions beyond some correlation time, their mean squared displacements exhibit strikingly different behaviours: depending on the model crossovers from anomalous to normal diffusion are observed, as well as a priori unexpected dependencies of the effective diffusion coefficient on the correlation exponent. Our observations of the non-universality of random-diffusivity viscoelastic anomalous diffusion are important for the analysis of experiments and a better understanding of the physical origins of 'viscoelastic yet non-Gaussian' diffusion. KW - diffusion KW - anomalous diffusion KW - non-Gaussianity KW - fractional Brownian motion Y1 - 2020 U6 - https://doi.org/10.1088/1367-2630/aba390 SN - 1367-2630 VL - 22 PB - Dt. Physikalische Ges. CY - Bad Honnef ER - TY - JOUR A1 - Quarmby, Andrew James A1 - Khajooei, Mina A1 - Kurtz, Philip A1 - Henschke, Jakob A1 - Kim, MyoungHwee A1 - Mayer, Frank A1 - Engel, Tilman T1 - Unexpected running perturbations BT - reliability and validity of a treadmill running protocol with analysis of provoked reflex activity in the lower extremities JF - Frontiers in sports and active living N2 - Introduction Balance is vital for human health and experiments have been conducted to measure the mechanisms of postural control, for example studying reflex responses to simulated perturbations. Such studies are frequent in walking but less common in running, and an understanding of reflex responses to trip-like disturbances could enhance our understanding of human gait and improve approaches to training and rehabilitation. Therefore, the primary aim of this study was to investigate the technical validity and reliability of a treadmill running protocol with perturbations. A further exploratory aim was to evaluate the associated neuromuscular reflex responses to the perturbations, in the lower limbs. Methods Twelve healthy participants completed a running protocol (9 km/h) test-retest (2 weeks apart), whereby 30 unilateral perturbations were executed via the treadmill belts (presets:2.0 m/s amplitude;150 ms delay (post-heel contact);100ms duration). Validity of the perturbations was assessed via mean +/- SD comparison, percentage error calculation between the preset and recorded perturbation characteristics (PE%), and coefficient of variation (CV%). Test-retest reliability (TRV%) and Bland-Altman analysis (BLA; bias +/- 1.96 * SD) was calculated for reliability. To measure reflex activity, electromyography (EMG) was applied in both legs. EMG amplitudes (root mean square normalized to unperturbed strides) and latencies [ms] were analysed descriptively. Results Left-side perturbation amplitude was 1.9 +/- 0.1 m/s, delay 105 +/- 2 ms, and duration 78 +/- 1 ms. Right-side perturbation amplitude was 1.9 +/- 0.1 m/s, delay 118 +/- 2 ms, duration 78 +/- 1 ms. PE% ranged from 5-30% for the recorded perturbations. CV% of the perturbations ranged from 19.5-76.8%. TRV% for the perturbations was 6.4-16.6%. BLA for the left was amplitude: 0.0 +/- 0.3m/s, delay: 0 +/- 17 ms, duration: 2 +/- 13 ms, and for the right was amplitude: 0.1 +/- 0.7, delay: 4 +/- 40 ms, duration: 1 +/- 35 ms. EMG amplitudes ranged from 175 +/- 141%-454 +/- 359% in both limbs. Latencies were 109 +/- 12-116 +/- 23 ms in the tibialis anterior, and 128 +/- 49-157 +/- 20 ms in the biceps femoris. Discussion Generally, this study indicated sufficient validity and reliability of the current setup considering the technical challenges and limitations, although the reliability of the right-sided perturbations could be questioned. The protocol provoked reflex responses in the lower extremities, especially in the leading leg. Acute neuromusculoskeletal adjustments to the perturbations could be studied and compared in clinical and healthy running populations, and the protocol could be utilised to monitor chronic adaptations to interventions over time. KW - running KW - perturbation KW - EMG KW - reliability KW - stumbling KW - reflexes KW - split-belt treadmill KW - gait Y1 - 2023 U6 - https://doi.org/10.3389/fspor.2023.1129058 SN - 2624-9367 VL - 5 PB - Frontiers Media CY - Lausanne ER - TY - JOUR A1 - Post, Julia C. A1 - Class, Fabian A1 - Kohler, Ulrich T1 - Unit nonresponse biases in estimates of SARS-CoV-2 prevalence JF - Survey research methods N2 - Since COVID-19 became a pandemic, many studies are being conducted to get a better understanding of the disease itself and its spread. One crucial indicator is the prevalence of SARS-CoV-2 infections. Since this measure is an important foundation for political decisions, its estimate must be reliable and unbiased. This paper presents reasons for biases in prevalence estimates due to unit nonresponse in typical studies. Since it is difficult to avoid bias in situations with mostly unknown nonresponse mechanisms, we propose the maximum amount of bias as one measure to assess the uncertainty due to nonresponse. An interactive web application is presented that calculates the limits of such a conservative unit nonresponse confidence interval (CUNCI). KW - COVID-19 KW - prevalence KW - probability samples KW - unit nonresponse KW - conservative confidence limits KW - nonresponse bias Y1 - 2020 U6 - https://doi.org/10.18148/srm/2020.v14i2.7755 SN - 1864-3361 VL - 14 IS - 2 SP - 115 EP - 121 PB - European Survey Research Association CY - Duisburg ER - TY - JOUR A1 - Seržant, Ilja A. A1 - Moroz, George A. T1 - Universal attractors in language evolution provide evidence for the kinds of efficiency pressures involved JF - Humanities & Social Sciences Communications N2 - Efficiency is central to understanding the communicative and cognitive underpinnings of language. However, efficiency management is a complex mechanism in which different efficiency effects-such as articulatory, processing and planning ease, mental accessibility, and informativity, online and offline efficiency effects-conspire to yield the coding of linguistic signs. While we do not yet exactly understand the interactional mechanism of these different effects, we argue that universal attractors are an important component of any dynamic theory of efficiency that would be aimed at predicting efficiency effects across languages. Attractors are defined as universal states around which language evolution revolves. Methodologically, we approach efficiency from a cross-linguistic perspective on the basis of a world-wide sample of 383 languages from 53 families, balancing all six macro-areas (Eurasia, North and South America, Australia, Africa, and Oceania). We explore the grammatical domain of verbal person-number subject indexes. We claim that there is an attractor state in this domain to which languages tend to develop and tend not to leave if they happen to comply with the attractor in their earlier stages of evolution. The attractor is characterized by different lengths for each person and number combination, structured along Zipf's predictions. Moreover, the attractor strongly prefers non-compositional, cumulative coding of person and number. On the basis of these and other properties of the attractor, we conclude that there are two domains in which efficiency pressures are most powerful: strive towards less processing and articulatory effort. The latter, however, is overridden by constant information flow. Strive towards lower lexicon complexity and memory costs are weaker efficiency pressures for this grammatical category due to its order of frequency. KW - Duration KW - Explanations KW - Redundancy KW - Pronouns KW - Usage Y1 - 2022 U6 - https://doi.org/10.1057/s41599-022-01072-0 SN - 2662-9992 VL - 9 IS - 1 PB - Springer Nature CY - London ER - TY - JOUR A1 - Sposini, Vittoria A1 - Grebenkov, Denis S. A1 - Metzler, Ralf A1 - Oshanin, Gleb A1 - Seno, Flavio T1 - Universal spectral features of different classes of random-diffusivity processes JF - New Journal of Physics N2 - Stochastic models based on random diffusivities, such as the diffusing-diffusivity approach, are popular concepts for the description of non-Gaussian diffusion in heterogeneous media. Studies of these models typically focus on the moments and the displacement probability density function. Here we develop the complementary power spectral description for a broad class of random-diffusivity processes. In our approach we cater for typical single particle tracking data in which a small number of trajectories with finite duration are garnered. Apart from the diffusing-diffusivity model we study a range of previously unconsidered random-diffusivity processes, for which we obtain exact forms of the probability density function. These new processes are different versions of jump processes as well as functionals of Brownian motion. The resulting behaviour subtly depends on the specific model details. Thus, the central part of the probability density function may be Gaussian or non-Gaussian, and the tails may assume Gaussian, exponential, log-normal, or even power-law forms. For all these models we derive analytically the moment-generating function for the single-trajectory power spectral density. We establish the generic 1/f²-scaling of the power spectral density as function of frequency in all cases. Moreover, we establish the probability density for the amplitudes of the random power spectral density of individual trajectories. The latter functions reflect the very specific properties of the different random-diffusivity models considered here. Our exact results are in excellent agreement with extensive numerical simulations. KW - diffusion KW - power spectrum KW - random diffusivity KW - single trajectories Y1 - 2020 U6 - https://doi.org/10.1088/1367-2630/ab9200 SN - 1367-2630 VL - 22 IS - 6 PB - Dt. Physikalische Ges. CY - Bad Honnef ER - TY - JOUR A1 - Ritschel, Stefan A1 - Cherstvy, Andrey G. A1 - Metzler, Ralf T1 - Universality of delay-time averages for financial time series BT - analytical results, computer simulations, and analysis of historical stock-market prices JF - Journal of physics. Complexity N2 - We analyze historical data of stock-market prices for multiple financial indices using the concept of delay-time averaging for the financial time series (FTS). The region of validity of our recent theoretical predictions [Cherstvy A G et al 2017 New J. Phys. 19 063045] for the standard and delayed time-averaged mean-squared 'displacements' (TAMSDs) of the historical FTS is extended to all lag times. As the first novel element, we perform extensive computer simulations of the stochastic differential equation describing geometric Brownian motion (GBM) which demonstrate a quantitative agreement with the analytical long-term price-evolution predictions in terms of the delayed TAMSD (for all stock-market indices in crisis-free times). Secondly, we present a robust procedure of determination of the model parameters of GBM via fitting the features of the price-evolution dynamics in the FTS for stocks and cryptocurrencies. The employed concept of single-trajectory-based time averaging can serve as a predictive tool (proxy) for a mathematically based assessment and rationalization of probabilistic trends in the evolution of stock-market prices. KW - econophysics KW - geometric Brownian motion KW - time-series analysis Y1 - 2021 U6 - https://doi.org/10.1088/2632-072X/ac2220 SN - 2632-072X VL - 2 IS - 4 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Despujol, Ignacio A1 - Turró, Carlos A1 - Busquets, Jaime T1 - Universitat Politècnica de València’s Experience with EDX MOOC Initiatives During the Covid Lockdown JF - EMOOCs 2021 N2 - In March 2020, when massive lockdowns started to be enforced around the world to contain the spread of the COVID-19 pandemic, edX launched two initiatives to help students around the world providing free certificates for its courses, RAP, for member institutions and OCE, for any accredited academic institution. In this paper we analyze how Universitat Poltècnica de València contributed with its courses to both initiatives, providing almost 14,000 free certificate codes in total, and how UPV used the RAP initiative as a customer, describing the mechanism used to distribute more than 22,000 codes for free certificates to more than 7,000 UPV community members, what led to the achievement of more than 5,000 free certificates. We also comment the results of a post initiative survey answered by 1,612 UPV members about 3,241 edX courses, in which they communicated a satisfaction of 4,69 over 5 with the initiative. Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-517196 SN - 978-3-86956-512-5 VL - 2021 SP - 181 EP - 185 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Wiebeler, Christian A1 - Vollbrecht, Joachim A1 - Neuba, Adam A1 - Kitzerow, Heinz A1 - Schumacher, Stefan T1 - Unraveling the electrochemical and spectroscopic properties of neutral and negatively charged perylene tetraethylesters JF - Scientific reports N2 - A detailed investigation of the energy levels of perylene-3,4,9,10-tetracarboxylic tetraethylester as a representative compound for the whole family of perylene esters was performed. It was revealed via electrochemical measurements that one oxidation and two reductions take place. The bandgaps determined via the electrochemical approach are in good agreement with the optical bandgap obtained from the absorption spectra via a Tauc plot. In addition, absorption spectra in dependence of the electrochemical potential were the basis for extensive quantum-chemical calculations of the neutral, monoanionic, and dianionic molecules. For this purpose, calculations based on density functional theory were compared with post-Hartree-Fock methods and the CAM-B3LYP functional proved to be the most reliable choice for the calculation of absorption spectra. Furthermore, spectral features found experimentally could be reproduced with vibronic calculations and allowed to understand their origins. In particular, the two lowest energy absorption bands of the anion are not caused by absorption of two distinct electronic states, which might have been expected from vertical excitation calculations, but both states exhibit a strong vibronic progression resulting in contributions to both bands. Y1 - 2021 U6 - https://doi.org/10.1038/s41598-021-95551-0 SN - 2045-2322 VL - 11 IS - 1 PB - Macmillan Publishers Limited, part of Springer Nature CY - London ER - TY - JOUR A1 - Vilk, Ohad A1 - Aghion, Erez A1 - Avgar, Tal A1 - Beta, Carsten A1 - Nagel, Oliver A1 - Sabri, Adal A1 - Sarfati, Raphael A1 - Schwartz, Daniel K. A1 - Weiß, Matthias A1 - Krapf, Diego A1 - Nathan, Ran A1 - Metzler, Ralf A1 - Assaf, Michael T1 - Unravelling the origins of anomalous diffusion BT - from molecules to migrating storks JF - Physical review research / American Physical Society N2 - Anomalous diffusion or, more generally, anomalous transport, with nonlinear dependence of the mean-squared displacement on the measurement time, is ubiquitous in nature. It has been observed in processes ranging from microscopic movement of molecules to macroscopic, large-scale paths of migrating birds. Using data from multiple empirical systems, spanning 12 orders of magnitude in length and 8 orders of magnitude in time, we employ a method to detect the individual underlying origins of anomalous diffusion and transport in the data. This method decomposes anomalous transport into three primary effects: long-range correlations (“Joseph effect”), fat-tailed probability density of increments (“Noah effect”), and nonstationarity (“Moses effect”). We show that such a decomposition of real-life data allows us to infer nontrivial behavioral predictions and to resolve open questions in the fields of single-particle tracking in living cells and movement ecology. Y1 - 2022 U6 - https://doi.org/10.1103/PhysRevResearch.4.033055 SN - 2643-1564 VL - 4 IS - 3 PB - American Physical Society CY - College Park, MD ER - TY - JOUR A1 - Westphal, Andrea A1 - Vock, Miriam A1 - Kretschmann, Julia T1 - Unravelling the relationship between teacher-assigned grades, student personality, and standardized test scores JF - Frontiers in psychology / Frontiers Research Foundation N2 - The Big Five personality traits play a major role in student achievement. As such, there is consistent evidence that students that are more conscientious receive better teacher-assigned grades in secondary school. However, research often does not support the claim that students that are more conscientious similarly achieve higher scores in domain-specific standardized achievement tests. Based on the Invest-and-Accrue Model, we argue that conscientiousness explains to some extent why certain students receive better grades despite similar academic accomplishments (i.e., achieving similar scores in domain-specific standardized achievement tests). Therefore, the present study examines to what extent the relationship between student personality and teacher-assigned grades consists of direct as opposed to indirect associations (via subject-specific standardized test scores). We used a representative sample of 14,710 ninth-grade students to estimate these direct and indirect pathways in mathematics and German. Structural equation models showed that test scores explained between 8 and 11% of the variance in teacher-assigned grades in mathematics and German. The Big Five personality traits in students additionally explained between 8 and 10% of the variance in grades. Finally, the personality-grade relationship consisted of direct (0.02 | β| ≤ 0.27) and indirect associations via test scores (0.01 | β| ≤ 0.07). Conscientiousness explained discrepancies between teacher-assigned grades and students’ scores in domain-specific standardized tests to a greater extent than any of the other Big Five personality traits. Our findings suggest that students that are more conscientious may invest more effort to accomplish classroom goals, but fall short of mastery. KW - Big Five KW - student personality KW - teacher-assigned grades KW - grading practice KW - conscientiousness KW - mathematics KW - German KW - secondary school Y1 - 2020 U6 - https://doi.org/10.3389/fpsyg.2021.627440 SN - 1664-1078 IS - 12 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Kurths, Jürgen A1 - Agarwal, Ankit A1 - Shukla, Roopam A1 - Marwan, Norbert A1 - Maheswaran, Rathinasamy A1 - Caesar, Levke A1 - Krishnan, Raghavan A1 - Merz, Bruno T1 - Unravelling the spatial diversity of Indian precipitation teleconnections via a non-linear multi-scale approach JF - Nonlinear processes in geophysics N2 - A better understanding of precipitation dynamics in the Indian subcontinent is required since India's society depends heavily on reliable monsoon forecasts. We introduce a non-linear, multiscale approach, based on wavelets and event synchronization, for unravelling teleconnection influences on precipitation. We consider those climate patterns with the highest relevance for Indian precipitation. Our results suggest significant influences which are not well captured by only the wavelet coherence analysis, the state-of-the-art method in understanding linkages at multiple timescales. We find substantial variation across India and across timescales. In particular, El Niño–Southern Oscillation (ENSO) and the Indian Ocean Dipole (IOD) mainly influence precipitation in the south-east at interannual and decadal scales, respectively, whereas the North Atlantic Oscillation (NAO) has a strong connection to precipitation, particularly in the northern regions. The effect of the Pacific Decadal Oscillation (PDO) stretches across the whole country, whereas the Atlantic Multidecadal Oscillation (AMO) influences precipitation particularly in the central arid and semi-arid regions. The proposed method provides a powerful approach for capturing the dynamics of precipitation and, hence, helps improve precipitation forecasting. Y1 - 2019 U6 - https://doi.org/10.5194/npg-26-251-2019 SN - 1023-5809 SN - 1607-7946 VL - 26 IS - 3 SP - 251 EP - 266 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Goodwin, Guillaume C. H. A1 - Mudd, Simon M. A1 - Clubb, Fiona J. T1 - Unsupervised detection of salt marsh platforms BT - a topographic method JF - Earth surface dynamics N2 - Salt marshes filter pollutants, protect coastlines against storm surges, and sequester carbon, yet are under threat from sea level rise and anthropogenic modification. The sustained existence of the salt marsh ecosystem depends on the topographic evolution of marsh platforms. Quantifying marsh platform topography is vital for improving the management of these valuable landscapes. The determination of platform boundaries currently relies on supervised classification methods requiring near-infrared data to detect vegetation, or demands labour-intensive field surveys and digitisation. We propose a novel, unsupervised method to reproducibly isolate salt marsh scarps and platforms from a digital elevation model (DEM), referred to as Topographic Identification of Platforms (TIP). Field observations and numerical models show that salt marshes mature into subhorizontal platforms delineated by subvertical scarps. Based on this premise, we identify scarps as lines of local maxima on a slope raster, then fill landmasses from the scarps upward, thus isolating mature marsh platforms. We test the TIP method using lidar-derived DEMs from six salt marshes in England with varying tidal ranges and geometries, for which topographic platforms were manually isolated from tidal flats. Agreement between manual and unsupervised classification exceeds 94% for DEM resolutions of 1 m, with all but one site maintaining an accuracy superior to 90% for resolutions up to 3 m. For resolutions of 1 m, platforms detected with the TIP method are comparable in surface area to digitised platforms and have similar elevation distributions. We also find that our method allows for the accurate detection of local block failures as small as 3 times the DEM resolution. Detailed inspection reveals that although tidal creeks were digitised as part of the marsh platform, unsupervised classification categorises them as part of the tidal flat, causing an increase in false negatives and overall platform perimeter. This suggests our method may benefit from combination with existing creek detection algorithms. Fallen blocks and high tidal flat portions, associated with potential pioneer zones, can also lead to differences between our method and supervised mapping. Although pioneer zones prove difficult to classify using a topographic method, we suggest that these transition areas should be considered when analysing erosion and accretion processes, particularly in the case of incipient marsh platforms. Ultimately, we have shown that unsupervised classification of marsh platforms from high-resolution topography is possible and sufficient to monitor and analyse topographic evolution. Y1 - 2018 U6 - https://doi.org/10.5194/esurf-6-239-2018 SN - 2196-6311 SN - 2196-632X VL - 6 IS - 1 SP - 239 EP - 255 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Jones, Eppie R. A1 - González-Fortes, Gloria M. A1 - Connell, Sarah A1 - Siska, Veronika A1 - Eriksson, Anders A1 - Martiniano, Rui A1 - McLaughlin, Russell L. A1 - Llorente, Marcos Gallego A1 - Cassidy, Lara M. A1 - Gamba, Cristina A1 - Meshveliani, Tengiz A1 - Bar-Yosef, Ofer A1 - Mueller, Werner A1 - Belfer-Cohen, Anna A1 - Matskevich, Zinovi A1 - Jakeli, Nino A1 - Higham, Thomas F. G. A1 - Currat, Mathias A1 - Lordkipanidze, David A1 - Hofreiter, Michael A1 - Manica, Andrea A1 - Pinhasi, Ron A1 - Bradley, Daniel G. T1 - Upper Palaeolithic genomes reveal deep roots of modern Eurasians JF - Nature Communications N2 - We extend the scope of European palaeogenomics by sequencing the genomes of Late Upper Palaeolithic (13,300 years old, 1.4-fold coverage) and Mesolithic (9,700 years old, 15.4-fold) males from western Georgia in the Caucasus and a Late Upper Palaeolithic (13,700 years old, 9.5-fold) male from Switzerland. While we detect Late Palaeolithic-Mesolithic genomic continuity in both regions, we find that Caucasus hunter-gatherers (CHG) belong to a distinct ancient clade that split from western hunter-gatherers similar to 45 kya, shortly after the expansion of anatomically modern humans into Europe and from the ancestors of Neolithic farmers similar to 25 kya, around the Last Glacial Maximum. CHG genomes significantly contributed to the Yamnaya steppe herders who migrated into Europe similar to 3,000 BC, supporting a formative Caucasus influence on this important Early Bronze age culture. CHG left their imprint on modern populations from the Caucasus and also central and south Asia possibly marking the arrival of Indo-Aryan languages. Y1 - 2015 U6 - https://doi.org/10.1038/ncomms9912 SN - 2041-1723 VL - 6 PB - Nature Publishing Group CY - London ER -