TY - JOUR A1 - Bryant, Seth A1 - Davies, Evan A1 - Sol, David A1 - Davis, Sandy T1 - The progression of flood risk in southern Alberta since the 2013 flood JF - Journal of flood risk management N2 - After a century of semi-restricted floodplain development, Southern Alberta, Canada, was struck by the devastating 2013 Flood. Aging infrastructure and limited property-level floodproofing likely contributed to the $4-6 billion (CAD) losses. Following this catastrophe, Alberta has seen a revival in flood management, largely focused on structural protections. However, concurrent with the recent structural work was a 100,000+ increase in Calgary's population in the 5 years following the flood, leading to further densification of high-hazard areas. This study implements the novel Stochastic Object-based Flood damage Dynamic Assessment (SOFDA) model framework to quantify the progression of the direct-damage flood risk in a mature urban neighborhood after the 2013 Flood. Five years of remote-sensing data, property assessment records, and inundation simulations following the flood are used to construct the model. Results show that in these 5 years, vulnerability trends (like densification) have increased flood risk by 4%; however, recent structural mitigation projects have reduced overall flood risk by 47% for this case study. These results demonstrate that the flood management revival in Southern Alberta has largely been successful at reducing flood risk; however, the gains are under threat from continued development and densification absent additional floodproofing regulations. KW - Calgary KW - depth-damage functions KW - expected annual damages KW - flood risk KW - model KW - property level protection measures KW - risk analysis KW - risk dynamics Y1 - 2022 U6 - https://doi.org/10.1111/jfr3.12811 SN - 1753-318X VL - 15 IS - 3 PB - Wiley-Blackwell CY - Oxford ER - TY - JOUR A1 - Börnert-Ringleb, Moritz A1 - Westphal, Andrea A1 - Zaruba, Nicole A1 - Gutmann, Franziska A1 - Vock, Miriam T1 - The relationship between attitudes toward inclusion, beliefs about teaching and learning, and subsequent automatic evaluations amongst student teachers JF - Frontiers in education N2 - Teachers' attitudes toward inclusion are frequently cited as being an important predictor of how successfully a given inclusive school system is implemented. At the same time, beliefs about the nature of teaching and learning are discussed as a possible predictor of attitudes toward inclusion. However, more recent research emphasizes the need of considering implicit processes, such as automatic evaluations, when describing attitudes and beliefs. Previous evidence on the association of attitudes toward inclusion and beliefs about teaching and learning is solely based on explicit reports. Therefore, this study aims to examine the relationship between attitudes toward inclusion, beliefs about teaching and learning, and the subsequent automatic evaluations of pre-service teachers (N = 197). The results revealed differences between pre-service teachers' explicit attitudes/beliefs and their subsequent automatic evaluations. Differences in the relationship between attitudes toward inclusion and beliefs about teaching and learning occur when teachers focus either on explicit measures or automatic evaluations. These differences might be due to different facets of the same attitude object being represented. Relying solely on either explicit measures or automatic evaluations at the exclusion of the other might lead to erroneous assumptions about the relation of attitudes toward inclusion and beliefs about teaching and learning. KW - inclusion KW - attitudes KW - teaching KW - automatic evaluation KW - beliefs KW - implicit Y1 - 2020 U6 - https://doi.org/10.3389/feduc.2020.584464 SN - 2504-284X VL - 5 PB - Frontiers Media CY - Lausanne ER - TY - JOUR A1 - Mendel, Ralf R. A1 - Hercher, Thomas W. A1 - Zupok, Arkadiusz A1 - Hasnat, Muhammad Abrar A1 - Leimkühler, Silke T1 - The requirement of inorganic Fe-S clusters for the biosynthesis of the organometallic molybdenum cofactor JF - Inorganics : open access journal N2 - Iron-sulfur (Fe-S) clusters are essential protein cofactors. In enzymes, they are present either in the rhombic [2Fe-2S] or the cubic [4Fe-4S] form, where they are involved in catalysis and electron transfer and in the biosynthesis of metal-containing prosthetic groups like the molybdenum cofactor (Moco). Here, we give an overview of the assembly of Fe-S clusters in bacteria and humans and present their connection to the Moco biosynthesis pathway. In all organisms, Fe-S cluster assembly starts with the abstraction of sulfur froml-cysteine and its transfer to a scaffold protein. After formation, Fe-S clusters are transferred to carrier proteins that insert them into recipient apo-proteins. In eukaryotes like humans and plants, Fe-S cluster assembly takes place both in mitochondria and in the cytosol. Both Moco biosynthesis and Fe-S cluster assembly are highly conserved among all kingdoms of life. Moco is a tricyclic pterin compound with molybdenum coordinated through its unique dithiolene group. Moco biosynthesis begins in the mitochondria in a Fe-S cluster dependent step involving radical/S-adenosylmethionine (SAM) chemistry. An intermediate is transferred to the cytosol where the dithiolene group is formed, to which molybdenum is finally added. Further connections between Fe-S cluster assembly and Moco biosynthesis are discussed in detail. KW - Moco biosynthesis KW - Fe-S cluster assembly KW - l-cysteine desulfurase KW - ISC KW - SUF KW - NIF KW - iron KW - molybdenum KW - sulfur Y1 - 2020 U6 - https://doi.org/10.3390/inorganics8070043 SN - 2304-6740 VL - 8 IS - 7 PB - MDPI CY - Basel ER - TY - JOUR A1 - Serrano-Munoz, Itziar A1 - Mishurova, Tatiana A1 - Thiede, Tobias A1 - Sprengel, Maximilian A1 - Kromm, Arne A1 - Nadammal, Naresh A1 - Nolze, Gert A1 - Saliwan-Neumann, Romeo A1 - Evans, Alexander A1 - Bruno, Giovanni T1 - The residual stress in as-built laser powder bed fusion IN718 alloy as a consequence of the scanning strategy induced microstructure JF - Scientific reports N2 - The effect of two types of scanning strategies on the grain structure and build-up of Residual Stress (RS) has been investigated in an as-built IN718 alloy produced by Laser Powder Bed Fusion (LPBF). The RS state has been investigated by X-ray diffraction techniques. The microstructural characterization was performed principally by Electron Backscatter Diffraction (EBSD), where the application of a post-measurement refinement technique enables small misorientations (< 2 degrees) to be resolved. Kernel average misorientation (KAM) distributions indicate that preferably oriented columnar grains contain higher levels of misorientation, when compared to elongated grains with lower texture. The KAM distributions combined with X-ray diffraction stress maps infer that the increased misorientation is induced via plastic deformation driven by the thermal stresses, acting to self-relieve stress. The possibility of obtaining lower RS states in the build direction as a consequence of the influence of the microstructure should be considered when envisaging scanning strategies aimed at the mitigation of RS. KW - EBSD KW - components KW - deposition KW - diffraction KW - distortion KW - heat-treatment KW - mechanical properties KW - melting slm KW - superalloys KW - texture Y1 - 2020 U6 - https://doi.org/10.1038/s41598-020-71112-9 SN - 2045-2322 VL - 10 IS - 1 PB - Macmillan Publishers Limited, part of Springer Nature CY - London ER - TY - JOUR A1 - Reich, Eli T1 - The return of liberal rabbinic education to Berlin BT - Abraham Geiger College, Zacharias Frankel College and the School of Jewish Theology JF - Nordisk judaistik = Scandinavian Jewish studies N2 - In Berlin two rabbinical seminaries, a Reform and a Conservative, have recently been established. The historical and intellectual roots of these institutions in the nineteenth century is sketched, and then contrasted with the present curriculum and the religious profile of the students. Some theological questions for the future of these projects conclude the article. KW - Abraham Geiger College KW - Zacharias Frankel College KW - the School of Jewish Theology KW - rabbinic education in Berlin Y1 - 2020 U6 - https://doi.org/10.30752/nj.84891 SN - 0348-1646 SN - 2343-4929 VL - 31 IS - 1 SP - 87 EP - 92 PB - Donner Institute CY - Åbo ER - TY - JOUR A1 - Bielcik, Milos A1 - Aguilar-Trigueros, Carlos A. A1 - Lakovic, Milica A1 - Jeltsch, Florian A1 - Rillig, Matthias C. T1 - The role of active movement in fungal ecology and community assembly JF - Movement Ecology N2 - Movement ecology aims to provide common terminology and an integrative framework of movement research across all groups of organisms. Yet such work has focused on unitary organisms so far, and thus the important group of filamentous fungi has not been considered in this context. With the exception of spore dispersal, movement in filamentous fungi has not been integrated into the movement ecology field. At the same time, the field of fungal ecology has been advancing research on topics like informed growth, mycelial translocations, or fungal highways using its own terminology and frameworks, overlooking the theoretical developments within movement ecology. We provide a conceptual and terminological framework for interdisciplinary collaboration between these two disciplines, and show how both can benefit from closer links: We show how placing the knowledge from fungal biology and ecology into the framework of movement ecology can inspire both theoretical and empirical developments, eventually leading towards a better understanding of fungal ecology and community assembly. Conversely, by a greater focus on movement specificities of filamentous fungi, movement ecology stands to benefit from the challenge to evolve its concepts and terminology towards even greater universality. We show how our concept can be applied for other modular organisms (such as clonal plants and slime molds), and how this can lead towards comparative studies with the relationship between organismal movement and ecosystems in the focus. KW - Filamentous fungi KW - Microbial community KW - Active movement KW - Modular organisms KW - Interference competition KW - Fungal space searching algorithms KW - Fungal foraging KW - Fungal highways KW - Clonal plants KW - Slime molds Y1 - 2019 U6 - https://doi.org/10.1186/s40462-019-0180-6 SN - 2051-3933 VL - 7 IS - 1 PB - BMC CY - London ER - TY - JOUR A1 - Rothermel, Ann-Kathrin T1 - The role of evidence-based misogyny in antifeminist online communities of the ‘manosphere’ JF - Big data & society N2 - In recent years, there have been a growing number of online and offline attacks linked to a loosely connected network of misogynist and antifeminist online communities called ‘the manosphere’. Since 2016, the ideas spread among and by groups of the manosphere have also become more closely aligned with those of other Far-Right online networks. In this commentary, I explore the role of what I term ‘evidence-based misogyny’ for mobilization and radicalization into the antifeminist and misogynist subcultures of the manosphere. Evidence-based misogyny is a discursive strategy, whereby members of the manosphere refer to (and misinterpret) knowledge in the form of statistics, studies, news items and pop-culture and mimic accepted methods of knowledge presentation to support their essentializing, polarizing views about gender relations in society. Evidence-based misogyny is a core aspect for manosphere-related mobilization as it provides a false sense of authority and forges a collective identity, which is framed as a supposed ‘alternative’ to mainstream gender knowledge. Due to its core function to justify and confirm the misogynist sentiments of users, evidence-based misogyny serves as connector between the manosphere and both mainstream conservative as well as other Far-Right and conspiratorial discourses. KW - misogyny KW - male supremacy KW - far right KW - discourse KW - incels KW - radicalization KW - antifeminist KW - men's rights KW - manosphere Y1 - 2023 U6 - https://doi.org/10.1177/20539517221145671 SN - 2053-9517 VL - 10 IS - 1 PB - Sage CY - Thousand Oaks, Calif. ER - TY - JOUR A1 - Johann, Kornelia A1 - Kleinert, Maximilian A1 - Klaus, Susanne T1 - The role of GDF15 as a myomitokine JF - Cells N2 - Growth differentiation factor 15 (GDF15) is a cytokine best known for affecting systemic energy metabolism through its anorectic action. GDF15 expression and secretion from various organs and tissues is induced in different physiological and pathophysiological states, often linked to mitochondrial stress, leading to highly variable circulating GDF15 levels. In skeletal muscle and the heart, the basal expression of GDF15 is very low compared to other organs, but GDF15 expression and secretion can be induced in various stress conditions, such as intense exercise and acute myocardial infarction, respectively. GDF15 is thus considered as a myokine and cardiokine. GFRAL, the exclusive receptor for GDF15, is expressed in hindbrain neurons and activation of the GDF15-GFRAL pathway is linked to an increased sympathetic outflow and possibly an activation of the hypothalamic-pituitary-adrenal (HPA) stress axis. There is also evidence for peripheral, direct effects of GDF15 on adipose tissue lipolysis and possible autocrine cardiac effects. Metabolic and behavioral outcomes of GDF15 signaling can be beneficial or detrimental, likely depending on the magnitude and duration of the GDF15 signal. This is especially apparent for GDF15 production in muscle, which can be induced both by exercise and by muscle disease states such as sarcopenia and mitochondrial myopathy. KW - anorexia KW - appetite regulation KW - cardiokine KW - cytokine KW - exercise KW - mitochondria KW - muscle KW - myokine KW - myopathy KW - sarcopenia Y1 - 2021 U6 - https://doi.org/10.3390/cells10112990 SN - 2073-4409 VL - 10 IS - 11 PB - MDPI CY - Basel ER - TY - JOUR A1 - Reese, Ronja A1 - Levermann, Anders A1 - Albrecht, Torsten A1 - Seroussi, Helene A1 - Winkelmann, Ricarda T1 - The role of history and strength of the oceanic forcing in sea level projections from Antarctica with the Parallel Ice Sheet Model JF - The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union N2 - Mass loss from the Antarctic Ice Sheet constitutes the largest uncertainty in projections of future sea level rise. Ocean-driven melting underneath the floating ice shelves and subsequent acceleration of the inland ice streams are the major reasons for currently observed mass loss from Antarctica and are expected to become more important in the future. Here we show that for projections of future mass loss from the Antarctic Ice Sheet, it is essential (1) to better constrain the sensitivity of sub-shelf melt rates to ocean warming and (2) to include the historic trajectory of the ice sheet. In particular, we find that while the ice sheet response in simulations using the Parallel Ice Sheet Model is comparable to the median response of models in three Antarctic Ice Sheet Intercomparison projects - initMIP, LARMIP-2 and ISMIP6 - conducted with a range of ice sheet models, the projected 21st century sea level contribution differs significantly depending on these two factors. For the highest emission scenario RCP8.5, this leads to projected ice loss ranging from 1:4 to 4:0 cm of sea level equivalent in simulations in which ISMIP6 ocean forcing drives the PICO ocean box model where parameter tuning leads to a comparably low sub-shelf melt sensitivity and in which no surface forcing is applied. This is opposed to a likely range of 9:1 to 35:8 cm using the exact same initial setup, but emulated from the LARMIP-2 experiments with a higher melt sensitivity, even though both projects use forcing from climate models and melt rates are calibrated with previous oceanographic studies. Furthermore, using two initial states, one with a previous historic simulation from 1850 to 2014 and one starting from a steady state, we show that while differences between the ice sheet configurations in 2015 seem marginal at first sight, the historic simulation increases the susceptibility of the ice sheet to ocean warming, thereby increasing mass loss from 2015 to 2100 by 5% to 50 %. Hindcasting past ice sheet changes with numerical models would thus provide valuable tools to better constrain projections. Our results emphasize that the uncertainty that arises from the forcing is of the same order of magnitude as the ice dynamic response for future sea level projections. Y1 - 2020 U6 - https://doi.org/10.5194/tc-14-3097-2020 SN - 1994-0416 SN - 1994-0424 VL - 14 IS - 9 SP - 3097 EP - 3110 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Fairey, Brenton J. A1 - Timmerman, Martin Jan A1 - Sudo, Masafumi A1 - Tsikos, Harilaos T1 - The role of hydrothermal activity in the formation of Karst-hosted manganese deposits of the Postmasburg Mn Field, Northern Cape Province, South Africa JF - Minerals N2 - The Postmasburg Manganese Field (PMF), Northern Cape Province, South Africa, once represented one of the largest sources of manganese ore worldwide. Two belts of manganese ore deposits have been distinguished in the PMF, namely the Western Belt of ferruginous manganese ores and the Eastern Belt of siliceous manganese ores. Prevailing models of ore formation in these two belts invoke karstification of manganese-rich dolomites and residual accumulation of manganese wad which later underwent diagenetic and low-grade metamorphic processes. For the most part, the role of hydrothermal processes and metasomatic alteration towards ore formation has not been adequately discussed. Here we report an abundance of common and some rare Al-, Na-, K- and Ba-bearing minerals, particularly aegirine, albite, microcline, banalsite, serandite-pectolite, paragonite and natrolite in Mn ores of the PMF, indicative of hydrothermal influence. Enrichments in Na, K and/or Ba in the ores are generally on a percentage level for most samples analysed through bulk-rock techniques. The presence of As-rich tokyoite also suggests the presence of As and V in the hydrothermal fluid. The fluid was likely oxidized and alkaline in nature, akin to a mature basinal brine. Various replacement textures, particularly of Na- and K- rich minerals by Ba-bearing phases, suggest sequential deposition of gangue as well as ore-minerals from the hydrothermal fluid, with Ba phases being deposited at a later stage. The stratigraphic variability of the studied ores and their deviation from the strict classification of ferruginous and siliceous ores in the literature, suggests that a re-evaluation of genetic models is warranted. New Ar-Ar ages for K-feldspars suggest a late Neoproterozoic timing for hydrothermal activity. This corroborates previous geochronological evidence for regional hydrothermal activity that affected Mn ores at the PMF but also, possibly, the high-grade Mn ores of the Kalahari Manganese Field to the north. A revised, all-encompassing model for the development of the manganese deposits of the PMF is then proposed, whereby the source of metals is attributed to underlying carbonate rocks beyond the Reivilo Formation of the Campbellrand Subgroup. The main process by which metals are primarily accumulated is attributed to karstification of the dolomitic substrate. The overlying Asbestos Hills Subgroup banded iron formation (BIF) is suggested as a potential source of alkali metals, which also provides a mechanism for leaching of these BIFs to form high-grade residual iron ore deposits. KW - manganese ore KW - Postmasburg manganese field KW - hydrothermal KW - karst KW - South Africa Y1 - 2019 U6 - https://doi.org/10.3390/min9070408 SN - 2075-163X VL - 9 IS - 7 PB - MDPI CY - Basel ER -