TY - JOUR A1 - Ogunkola, Moses Olalekan A1 - Guiraudie-Capraz, Gaelle A1 - Féron, François A1 - Leimkühler, Silke T1 - The Human Mercaptopyruvate Sulfurtransferase TUM1 Is Involved in Moco Biosynthesis, Cytosolic tRNA Thiolation and Cellular Bioenergetics in Human Embryonic Kidney Cells JF - Biomolecules N2 - Sulfur is an important element that is incorporated into many biomolecules in humans. The incorporation and transfer of sulfur into biomolecules is, however, facilitated by a series of different sulfurtransferases. Among these sulfurtransferases is the human mercaptopyruvate sulfurtransferase (MPST) also designated as tRNA thiouridine modification protein (TUM1). The role of the human TUM1 protein has been suggested in a wide range of physiological processes in the cell among which are but not limited to involvement in Molybdenum cofactor (Moco) biosynthesis, cytosolic tRNA thiolation and generation of H2S as signaling molecule both in mitochondria and the cytosol. Previous interaction studies showed that TUM1 interacts with the L-cysteine desulfurase NFS1 and the Molybdenum cofactor biosynthesis protein 3 (MOCS3). Here, we show the roles of TUM1 in human cells using CRISPR/Cas9 genetically modified Human Embryonic Kidney cells. Here, we show that TUM1 is involved in the sulfur transfer for Molybdenum cofactor synthesis and tRNA thiomodification by spectrophotometric measurement of the activity of sulfite oxidase and liquid chromatography quantification of the level of sulfur-modified tRNA. Further, we show that TUM1 has a role in hydrogen sulfide production and cellular bioenergetics. KW - Moco biosynthesis KW - sulfite oxidase KW - cytosolic tRNA thiolation KW - 5-methoxycarbonylmethyl-2-thiouridine KW - H2S biosynthesis KW - cellular bioenergetics Y1 - 2023 U6 - https://doi.org/10.3390/biom13010144 SN - 2218-273X VL - 13 SP - 1 EP - 23 PB - MDPI CY - Basel, Schweiz ET - 1 ER - TY - JOUR A1 - Marggraf, Lara Christin A1 - Lindecke, Oliver A1 - Voigt, Christian C. A1 - Pētersons, Gunārs A1 - Voigt-Heucke, Silke Luise T1 - Nathusius’ bats, Pipistrellus nathusii, bypass mating opportunities of their own species, but respond to foraging heterospecifics on migratory transit flights JF - Frontiers in Ecology and Evolution N2 - In late summer, migratory bats of the temperate zone face the challenge of accomplishing two energy-demanding tasks almost at the same time: migration and mating. Both require information and involve search efforts, such as localizing prey or finding potential mates. In non-migrating bat species, playback studies showed that listening to vocalizations of other bats, both con-and heterospecifics, may help a recipient bat to find foraging patches and mating sites. However, we are still unaware of the degree to which migrating bats depend on con-or heterospecific vocalizations for identifying potential feeding or mating opportunities during nightly transit flights. Here, we investigated the vocal responses of Nathusius’ pipistrelle bats, Pipistrellus nathusii, to simulated feeding and courtship aggregations at a coastal migration corridor. We presented migrating bats either feeding buzzes or courtship calls of their own or a heterospecific migratory species, the common noctule, Nyctalus noctula. We expected that during migratory transit flights, simulated feeding opportunities would be particularly attractive to bats, as well as simulated mating opportunities which may indicate suitable roosts for a stopover. However, we found that when compared to the natural silence of both pre-and post-playback phases, bats called indifferently during the playback of conspecific feeding sounds, whereas P. nathusii echolocation call activity increased during simulated feeding of N. noctula. In contrast, the call activity of P. nathusii decreased during the playback of conspecific courtship calls, while no response could be detected when heterospecific call types were broadcasted. Our results suggest that while on migratory transits, P. nathusii circumnavigate conspecific mating aggregations, possibly to save time or to reduce the risks associated with social interactions where aggression due to territoriality might be expected. This avoidance behavior could be a result of optimization strategies by P. nathusii when performing long-distance migratory flights, and it could also explain the lack of a response to simulated conspecific feeding. However, the observed increase of activity in response to simulated feeding of N. noctula, suggests that P. nathusii individuals may be eavesdropping on other aerial hawking insectivorous species during migration, especially if these occupy a slightly different foraging niche. KW - playback KW - phonotaxis KW - bats KW - acoustic communication KW - animal migration KW - eavesdropping KW - echolocation KW - Pipistrellus nathusii Y1 - 2023 U6 - https://doi.org/10.3389/fevo.2022.908560 SN - 2296-701X SP - 1 EP - 10 PB - Frontiers CY - Lausanne, Schweiz ER - TY - JOUR A1 - Brinkmann, Pia A1 - Köllner, Nicole A1 - Merk, Sven A1 - Beitz, Toralf A1 - Altenberger, Uwe A1 - Löhmannsröben, Hans-Gerd T1 - Comparison of handheld and echelle spectrometer to assess copper in ores by means of laser-induced breakdown spectroscopy (LIBS) JF - Minerals N2 - Its properties make copper one of the world’s most important functional metals. Numerous megatrends are increasing the demand for copper. This requires the prospection and exploration of new deposits, as well as the monitoring of copper quality in the various production steps. A promising technique to perform these tasks is Laser Induced Breakdown Spectroscopy (LIBS). Its unique feature, among others, is the ability to measure on site without sample collection and preparation. In this work, copper-bearing minerals from two different deposits are studied. The first set of field samples come from a volcanogenic massive sulfide (VMS) deposit, the second part from a stratiform sedimentary copper (SSC) deposit. Different approaches are used to analyze the data. First, univariate regression (UVR) is used. However, due to the strong influence of matrix effects, this is not suitable for the quantitative analysis of copper grades. Second, the multivariate method of partial least squares regression (PLSR) is used, which is more suitable for quantification. In addition, the effects of the surrounding matrices on the LIBS data are characterized by principal component analysis (PCA), alternative regression methods to PLSR are tested and the PLSR calibration is validated using field samples. KW - LIBS KW - copper-bearing minerals KW - UVR KW - PCA KW - PLSR Y1 - 2023 U6 - https://doi.org/10.3390/min13010113 SN - 2075-163X VL - 13 IS - 1 PB - MDPI CY - Basel ER - TY - JOUR A1 - Assen, Louisa T1 - Digitalization as a Provider of Sustainability? BT - The Role and Acceptance of Digital Technologies in Fashion Stores JF - Sustainability N2 - Digitalization, as well as sustainability, are gaining increased relevance and have attracted significant attention in research and practice. However, the research already published about this topic examining digitalization in the retail sector does not consider the acceptance of related innovations, nor their impact on sustainability. Therefore, this article critically analyzes the acceptance of customers towards digital technologies in fashion stores as well as their impact on sustainability in the textile industry. The comprehensive analysis of the literature and the current state of research provide the basis of this paper. Theoretical models, such as the Technology-Acceptance-Model (TAM) and the Unified Theory of Acceptance and Use of Technology 2 (UTAUT 2) enable the evaluation of expectations and acceptance, as well as the assessment of possible inhibitory factors for the subsequent descriptive and statistical examination of the acceptance of digital technologies in fashion stores. The research on this subject was examined in a quantitative way. The key findings show that customers do accept digital technologies in fashion stores. The final part of this contribution describes the innovative Digitalization 4 Sustainability Framework which shows that digital technologies at the point of sale (PoS) in fashion stores could have a positive impact on sustainability. Overall, this paper shows that it is particularly important for fashion stores to concentrate on their individual strengths and customer needs as well as to indicate a more sustainable way by using digital technologies, in order to achieve added value for the customers and to set themselves apart from the competition while designing a more sustainable future. Moreover, fashion stores should make it a point of their honor to harness the power of digitalization for sake of sustainability and economic value creation. KW - sustainability KW - digital technologies KW - customer acceptance KW - fashion industry Y1 - 2023 U6 - https://doi.org/10.3390/su15054621 SN - 2071-1050 VL - 15 IS - 5 PB - MDPI CY - Basel ER - TY - JOUR A1 - Eisenberg, Peter T1 - Große Erzählkunst: Anna Seghers’ ‚Der Ausflug der toten Mädchen‘ JF - Literarische Grammatik : wie Literatur- und Sprachwissenschaft voneinander profitieren können Y1 - 2023 SN - 978-3-8253-8608-5 SN - 978-3-8253-9504-9 U6 - https://doi.org/10.33675/2023-82538608 SP - 57 EP - 77 PB - Winter CY - Heidelberg ER - TY - BOOK A1 - Van Hal, Toon A1 - Van Loon, Zanna A1 - Mercelis, Wouter A1 - Steckley, John A1 - Peetermans, Andy A1 - Van Rooy, Raf A1 - Dionne, Fannie ED - Van Loon, Zanna ED - Steckley, John ED - Van Hal, Toon ED - Peetermans, Andy T1 - Anchored in ink BT - Pierre-Philippe Potier’s Elementa Grammaticae Huronicae (1745), a Jesuit grammar of Wendat BT - Die Elementa grammaticae Huronicae (1745) des Jesuiten Pierre-Philippe Potier, eine Grammatik der Wendat-Sprache N2 - This book serves as a gateway to the Elementa grammaticae Huronicae, an eighteenth-century grammar of the Wendat (‘Huron’) language by Jesuit Pierre-Philippe Potier (1708–1781). The volume falls into three main parts. The first part introduces the grammar and some of its contexts, offering information about the Huron-Wendat and Wyandot, the early modern Jesuit mission in New France and the Jesuits’ linguistic output. The heart of the volume is made up by its second part, a text edition of the Elementa. The third part presents some avenues of research by way of specific case studies. N2 - Dieses Buch hat das Ziel, die Elementa grammaticae Huronicae, eine im 18. Jahrhundert vom Jesuiten Pierre-Philippe Potier (1708–1781) erstellte Grammatik der Wendat-Sprache (d.h. des ‘Huronischen’), einem größeren Leserkreis zu eröffnen. Der Band gliedert sich in drei Hauptteile: Der erste Teil bietet eine Einführung zu der Grammatik und einigen relevanten Kontexten, mit Informationen über die Huron-Wendat und Wyandot, die frühneuzeitliche Jesuitenmission in Neufrankreich und die Schriften der Jesuiten auf dem Gebiet des Sprachstudiums. Das Kernstück des Bandes bildet der zweite Teil, eine Textausgabe der Elementa. Im dritten Teil werden anhand von spezifischen Fallstudien einige Forschungswege vorgestellt. KW - missionary grammar KW - history of linguistics KW - circulation of knowledge KW - early modern manuscript culture KW - Iroquoian languages KW - Missionarsgrammatik KW - Geschichte der Sprachwissenschaft KW - Wissenszirkulation KW - frühneuzeitliche Manuskriptkultur KW - irokesische Sprachen Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-513062 SN - 978-3-86956-516-3 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Ullrich, Rebecca A1 - Abramowicz, Isidoro T1 - Ein unbekannter Piyyut für Schabbat aus Reckendorf JF - Genisa-Blätter IV Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-584897 SN - 978-3-86956-539-2 SP - 73 EP - 82 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - THES A1 - Towara, Cécile T1 - Die Errichtung des Deutsch-Französischen Bürgerfonds nach Art. 12 des Vertrags von Aachen T1 - The establishment of the Franco-German civic fund according to Art. 12 of the treaty of Aachen T1 - La création du fonds citoyen franco-allemand selon l'art. 12 du traité d'Aix-la-Chapelle BT - Herausforderungen und Perspektiven BT - challenges and perspectives BT - défis et perspectives T2 - MEGA-Schriftenreihe N2 - Die Arbeit befasst sich mit der Vorgabe des Aachener Vertrages, welche mit der Schaffung des Deutsch-Französischen Bürgerfonds die Zivilgesellschaften der beiden Partnerländer und ihr weiteres Zusammenwachsen in den Fokus genommen haben. Hierzu wird auf die Frage eingegangen, warum eine weitere deutsch-französische Organisation gerade in diesen Zeiten notwendig ist und warum ihr durch Ausgestaltung als möglichst eigenständige Institution die erforderliche Rolle als beständiger Motor für eine notwendige weitere Europäisierung zuteilwerden kann. Der Bürgerfonds soll mithilfe seiner finanziellen Unterstützungsleistungen des binationalen Austausches von Bürgerinitiativen, Stiftungen, Kulturzentren, Vereinen, Städtepartnerschaften und sonstigen Formen privaten Engagements als „Leuchtturmprojekt des Aachener Vertrages“ diejenigen ansprechen, welche bislang nicht als klassische stakeholder der deutsch-französischen Freundschaft bekannt geworden sind. Die Ausgestaltung des Bürgerfonds als eigenständige internationale Organisation erscheint vor dem Hintergrund dieser Zielsetzung die optimale Rechtsform. Seine generelle Aufbauorganisation sollte an der des Deutsch-Französischen Jugendwerks angelehnt werden. Insoweit war die Vorgabe der organisatorischen Einbindung des Bürgerfonds in das Jugendwerk im Rahmen der Pilotphase bis Ende 2022 nicht nur wegen der dort vorhandenen großen Expertise eine sinnvolle Entscheidung des Deutsch-Französischen Ministerrats. Eine Erweiterung des Verwaltungs- bzw. Kontrollgremiums in einem selbständigen Bürgerfonds durch Vertreter der Deutsch-Französischen Parlamentarischen Versammlung erscheint zur Gewährleistung von Transparenz und tagespolitischer Unabhängigkeit ebenso ratsam, wie seine zumindest partielle Öffnung für andere europäische Mitgliedsstaaten. Abschließend bleibt zu konstatieren, dass in den Zeiten kriselnder Demokratien und der COVID-Gefahr eine Hinwendung zu den Bürgern und ihren privaten bzw. para-öffentlichen Organisationsformen ebenso wichtig ist, wie die Förderung des Austausches der Bürger beider Länder im Herzen Europas mehr denn je hilft, Distanzen zu überwinden und transnationale Gemeinschaft zu erleben. N2 - Le travail porte sur les dispositions du Traité d'Aix-la-Chapelle qui, avec la création du Fonds citoyen franco-allemand, ont mis l'accent sur les sociétés civiles des deux pays partenaires et sur la poursuite de leur rapprochement. À cet égard, la question se pose pourquoi une organisation franco-allemande supplémentaire est-elle nécessaire et pourquoi, en devenant une institution autonome, peut-elle jouer le rôle nécessaire de moteur permanent pour une européanisation plus poussée. Le Fonds Citoyen, par son soutien financier à l'échange binational d'initiatives citoyennes, de fondations, de centres culturels, d'associations, de jumelages et d'autres formes d'engagement privé, doit s'adresser, en tant que "projet phare du Traité d'Aix-la-Chapelle", à ceux qui ne sont pas encore connus comme des parties prenantes classiques de l'amitié franco-allemande. Dans ce contexte, la forme juridique optimale du Fonds citoyen semble être celle d'une organisation internationale autonome. Son organisation générale devait s'inspirer de celle de l'Office franco-allemand pour la jeunesse. La décision du Conseil des ministres franco-allemand d'intégrer le Fonds citoyen dans l'organisation de l'Office franco-allemand pour la jeunesse dans le cadre de la phase pilote jusqu'à fin 2022 était donc judicieuse, et pas seulement en raison de la grande expertise qui y est disponible. L'élargissement de l'organe de gestion et de contrôle à un fonds citoyen autonome par des représentants de l'Assemblée parlementaire franco-allemande semble tout aussi conseillé pour garantir la transparence et l'indépendance politique au quotidien que son ouverture au moins partielle à d'autres États membres européens. En conclusion, il reste à constater qu'en ces temps de démocraties en crise et la crise sanitaire, il est tout aussi important de se tourner vers les citoyens et leurs formes d'organisation privées ou para-publiques que de favoriser les échanges entre les citoyens des deux pays au cœur de l'Europe aide plus que jamais à surmonter les distances et à vivre une communauté transnationale. N2 - This paper deals with the stipulations of the Aachen Treaty, which, with the creation of the Franco-German Citizens' Fund, focused on the civil societies of the two partner countries and their further growing together. To this end, the question is addressed as to why a further Franco-German organisation is necessary, especially in these times, and why it can be given the necessary role as a constant motor for a necessary further Europeanisation by being designed as an independent institution as far as possible. With the help of its financial support for the bi-national exchange of citizens' initiatives, foundations, cultural centres, associations, town twinning and other forms of private commitment, the Citizens' Fund is intended as a "lighthouse project of the Aachen Treaty" to appeal to those who have not yet become known as classic stakeholders in the Franco-German friend-ship. Against the background of this objective, the design of the citizens' fund as an independent international organisation appears to be the optimal legal form. Its general organisational struc-ture should be based on that of the Franco-German Youth Office. In this respect, the specification of the organisational integration of the Citizens' Fund into the Youth Office within the framework of the pilot phase until the end of 2022 was a sensible decision of the Franco-German Council of Ministers, not only because of the great expertise available there. An expansion of the administrative or supervisory body in an independent citizens' fund by representatives of the Franco-German Parliamentary Assembly seems just as advisable to guarantee transparency and day-to-day political independence as its at least partial opening to other European member states. In conclusion, it remains to be stated that in times of crumbling democracies and the danger of COVID, a turn to the citizens and their private or para-public forms of organisation is just as important as the promotion of exchange between the citizens of both countries in the heart of Europe helps more than ever to overcome distances and to experience transnational community. T3 - MEGA-Schriftenreihe - 9 KW - Deutsch-Französischer Bürgerfonds KW - internationale Organisation KW - Deutsch-Französische Parlamentarische Versammlung KW - Fonds Citoyen KW - organisation internationale KW - Assemblée parlementaire franco-allemande KW - Franco-German Citizens' Fund KW - international organisation KW - Franco-German Parliamentary Assembly KW - Deutsch-Französisches Jugendwerk KW - Office franco-allemand pour la jeunesse KW - Franco-German Youth Office Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-581051 SN - 2701-391X IS - 9 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Smith, Taylor A1 - Zotta, Ruxandra-Maria A1 - Boulton, Chris A. A1 - Lenton, Timothy M. A1 - Dorigo, Wouter A1 - Boers, Niklas T1 - Reliability of resilience estimation based on multi-instrument time series JF - Earth System Dynamics N2 - Many widely used observational data sets are comprised of several overlapping instrument records. While data inter-calibration techniques often yield continuous and reliable data for trend analysis, less attention is generally paid to maintaining higher-order statistics such as variance and autocorrelation. A growing body of work uses these metrics to quantify the stability or resilience of a system under study and potentially to anticipate an approaching critical transition in the system. Exploring the degree to which changes in resilience indicators such as the variance or autocorrelation can be attributed to non-stationary characteristics of the measurement process – rather than actual changes in the dynamical properties of the system – is important in this context. In this work we use both synthetic and empirical data to explore how changes in the noise structure of a data set are propagated into the commonly used resilience metrics lag-one autocorrelation and variance. We focus on examples from remotely sensed vegetation indicators such as vegetation optical depth and the normalized difference vegetation index from different satellite sources. We find that time series resulting from mixing signals from sensors with varied uncertainties and covering overlapping time spans can lead to biases in inferred resilience changes. These biases are typically more pronounced when resilience metrics are aggregated (for example, by land-cover type or region), whereas estimates for individual time series remain reliable at reasonable sensor signal-to-noise ratios. Our work provides guidelines for the treatment and aggregation of multi-instrument data in studies of critical transitions and resilience. Y1 - 2023 U6 - https://doi.org/10.5194/esd-14-173-2023 SN - 2190-4987 VL - 14 SP - 173 EP - 183 PB - Copernicus Publications CY - Göttingen ER - TY - JOUR A1 - Bosch, Jannis A1 - Wilbert, Jürgen T1 - The impact of social comparison processes on self-evaluation of performance, self-concept, and task interest JF - Frontiers in education N2 - Development of self-concept and task interest has been shown to be affected by social comparison processes in a variety of cross-sectional studies. A potential explanation for these effects is an effect of social comparative performance feedback on an individual’s self-evaluation of performance, which in turn influences development of self-concept and task interest. There are, however, only few studies addressing this topic with experimental designs. This study was aimed at closing this research gap by experimentally manipulating social comparative performance. Feedback given was based on 2 × 2 experimental conditions: social position (high vs. low) and average performance of the reference group (high vs. low). Results show a strong effect of social position on self-evaluation of performance and smaller effects on self-concept and task interest. KW - social comparison KW - self-evaluation KW - self-concept KW - interest KW - contrast effects Y1 - 2023 U6 - https://doi.org/10.3389/feduc.2023.1033488 SN - 2504-284X VL - 8 PB - Frontiers Media CY - Lausanne ER -