TY - JOUR A1 - Bauman, Zygmunt T1 - Local Orders, Global Chaos JF - Geographische Revue : Zeitschrift für Literatur und Diskussion Y1 - 1999 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-23782 SN - 1438-3039 VL - 1 IS - 1 SP - 64 EP - 72 ER - TY - JOUR A1 - Mitchell, Don T1 - The end of culture? BT - culturalism and cultural geography in the Anglo-American “University of Excellence” JF - Geographische Revue : Zeitschrift für Literatur und Diskussion N2 - Content: -”Post-Culture” -Cultural Studies, Geography, and Culturalism -Taking Culture Seriously in the Post-Cultural World -Conclusion Y1 - 2000 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-24016 SN - 1438-3039 VL - 2 IS - 2 SP - 3 EP - 17 ER - TY - JOUR A1 - Smith, Neil T1 - Marxism and Geography in the Anglophone World JF - Geographische Revue : Zeitschrift für Literatur und Diskussion N2 - Content: Activism: The Origins of Marxism in English-language Geography After the Revolution: Critique, Institutionalization and Backlash Marxist Geography Today: Scale, Labour Geography, Activism Conclusion Y1 - 2001 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-24357 SN - 1438-3039 VL - 3 IS - 2 SP - 5 EP - 21 ER - TY - JOUR A1 - Harvey, David T1 - Globalization and the “Spatial Fix” JF - Geographische Revue : Zeitschrift für Literatur und Diskussion Y1 - 2001 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-24366 SN - 1438-3039 VL - 3 IS - 2 SP - 23 EP - 30 ER - TY - JOUR A1 - Dipper, Stefanie A1 - Götze, Michael A1 - Stede, Manfred A1 - Wegst, Tillmann T1 - ANNIS BT - a linguistic database for exploring information structure JF - Interdisciplinary studies on information structure : ISIS ; working papers of the SFB 632 N2 - In this paper, we discuss the design and implementation of our first version of the database "ANNIS" ("ANNotation of Information Structure"). For research based on empirical data, ANNIS provides a uniform environment for storing this data together with its linguistic annotations. A central database promotes standardized annotation, which facilitates interpretation and comparison of the data. ANNIS is used through a standard web browser and offers tier-based visualization of data and annotations, as well as search facilities that allow for cross-level and cross-sentential queries. The paper motivates the design of the system, characterizes its user interface, and provides an initial technical evaluation of ANNIS with respect to data size and query processing. Y1 - 2004 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-8432 SN - 1866-4725 SN - 1614-4708 IS - 1 SP - 245 EP - 279 ER - TY - JOUR A1 - Hartmann, Katharina A1 - Zimmermann, Malte T1 - Focus strategies in chadic BT - the case of tangale revisited JF - Interdisciplinary studies on information structure : ISIS ; working papers of the SFB 632 N2 - We argue that the standard focus theories reach their limits when confronted with the focus systems of the Chadic languages. The backbone of the standard focus theories consists of two assumptions, both called into question by the languages under consideration. Firstly, it is standardly assumed that focus is generally marked by stress. The Chadic languages, however, exhibit a variety of different devices for focus marking. Secondly, it is assumed that focus is always marked. In Tangale, at least, focus is not marked consistently on all types of constituents. The paper offers two possible solutions to this dilemma. KW - tone languages KW - focus marking KW - focus movement Y1 - 2004 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-8423 SN - 1866-4725 SN - 1614-4708 IS - 1 SP - 207 EP - 243 ER - TY - JOUR A1 - Endriss, Cornelia A1 - Hinterwimmer, Stefan T1 - The influence of tense in adverbial quantification JF - Interdisciplinary studies on information structure : ISIS ; working papers of the SFB 632 N2 - We argue that there is a crucial difference between determiner and adverbial quantification. Following Herburger [2000] and von Fintel [1994], we assume that determiner quantifiers quantify over individuals and adverbial quantifiers over eventualities. While it is usually assumed that the semantics of sentences with determiner quantifiers and those with adverbial quantifiers basically come out the same, we will show by way of new data that quantification over events is more restricted than quantification over individuals. This is because eventualities in contrast to individuals have to be located in time which is done using contextual information according to a pragmatic resolution strategy. If the contextual information and the tense information given in the respective sentence contradict each other, the sentence is uninterpretable. We conclude that this is the reason why in these cases adverbial quantification, i.e. quantification over eventualities, is impossible whereas quantification over individuals is fine. KW - Adverbial Quantification KW - Covert Variables KW - Domain Restriction KW - Quantificational Variability Y1 - 2004 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-8409 SN - 1866-4725 SN - 1614-4708 IS - 1 SP - 121 EP - 151 ER - TY - JOUR A1 - Wagner, Andreas T1 - Unity in diversity BT - integrating different linguistic data in TUSNELDA JF - Interdisciplinary studies on information structure : ISIS ; working papers of the SFB 632 N2 - This paper describes the creation and preparation of TUSNELDA, a collection of corpus data built for linguistic research. This collection contains a number of linguistically annotated corpora which differ in various aspects such as language, text sorts / data types, encoded annotation levels, and linguistic theories underlying the annotation. The paper focuses on this variation on the one hand and the way how these heterogeneous data are integrated into one resource on the other hand. Y1 - 2005 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-8625 SN - 1866-4725 SN - 1614-4708 IS - 2 SP - 1 EP - 20 ER - TY - JOUR A1 - Witt, Andreas T1 - Multiple hierarchies BT - new aspects of an old solution JF - Interdisciplinary studies on information structure : ISIS ; working papers of the SFB 632 N2 - In this paper, we present the Multiple Annotation approach, which solves two problems: the problem of annotating overlapping structures, and the problem that occurs when documents should be annotated according to different, possibly heterogeneous tag sets. This approach has many advantages: it is based on XML, the modeling of alternative annotations is possible, each level can be viewed separately, and new levels can be added at any time. The files can be regarded as an interrelated unit, with the text serving as the implicit link. Two representations of the information contained in the multiple files (one in Prolog and one in XML) are described. These representations serve as a base for several applications. Y1 - 2005 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-8657 SN - 1866-4725 SN - 1614-4708 IS - 2 SP - 55 EP - 85 ER - TY - JOUR A1 - Meyer, Roland T1 - VP-fronting in Czech and Polish BT - a case study in corpus-oriented grammar research JF - Interdisciplinary studies on information structure : ISIS ; working papers of the SFB 632 N2 - Fronting of an infinite VP across a finite main verb-akin to German "VP-topicalization"-can be found also in Czech and Polish. The paper discusses evidence from large corpora for this process and some of its properties, both syntactic and information-structural. Based on this case, criteria for more user-friedly searching and retrieval of corpus data in syntactic research are being developed. Y1 - 2005 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-8662 SN - 1866-4725 SN - 1614-4708 IS - 2 SP - 87 EP - 115 ER - TY - JOUR A1 - Elbourne, Paul T1 - The Semantics of Ellipsis JF - Interdisciplinary studies on information structure : ISIS ; working papers of the SFB 632 N2 - There are four phenomena that are particularly troublesome for theories of ellipsis: the existence of sloppy readings when the relevant pronouns cannot possibly be bound; an ellipsis being resolved in such a way that an ellipsis site in the antecedent is not understood in the way it was there; an ellipsis site drawing material from two or more separate antecedents; and ellipsis with no linguistic antecedent. These cases are accounted for by means of a new theory that involves copying syntactically incomplete antecedent material and an analysis of silent VPs and NPs that makes them into higher order definite descriptions that can be bound into. KW - VP-ellipsis KW - NP-deletion KW - definite descriptions Y1 - 2005 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-8722 SN - 1866-4725 SN - 1614-4708 IS - 3 SP - 63 EP - 109 ER - TY - JOUR A1 - Fiedler, Ines A1 - Schwarz, Anne T1 - Out-of-focus encoding in Gur and Kwa JF - Interdisciplinary studies on information structure : ISIS ; working papers of the SFB 632 N2 - This paper investigates the structural properties of morphosyntactically marked focus constructions, focussing on the often neglected non-focal sentence part in African tone languages. Based on new empirical evidence from five Gur and Kwa languages, we claim that these focus expressions have to be analysed as biclausal constructions even though they do not represent clefts containing restrictive relative clauses. First, we relativize the partly overgeneralized assumptions about structural correspondences between the out-of-focus part and relative clauses, and second, we show that our data do in fact support the hypothesis of a clause coordinating pattern as present in clause sequences in narration. It is argued that we deal with a non-accidental, systematic feature and that grammaticalization may conceal such basic narrative structures. KW - ex-situ focus KW - focus marker KW - relative clause KW - conjunction KW - grammaticalization Y1 - 2005 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-8739 SN - 1866-4725 SN - 1614-4708 IS - 3 SP - 111 EP - 142 ER - TY - JOUR A1 - Jannedy, Stefanie A1 - Mendoza-Denton, Norma T1 - Structuring information through gesture and intonation JF - Interdisciplinary studies on information structure : ISIS ; working papers of the SFB 632 N2 - Face-to-face communication is multimodal. In unscripted spoken discourse we can observe the interaction of several "semiotic layers", modalities of information such as syntax, discourse structure, gesture, and intonation. We explore the role of gesture and intonation in structuring and aligning information in spoken discourse through a study of the co-occurrence of pitch accents and gestural apices. Metaphorical spatialization through gesture also plays a role in conveying the contextual relationships between the speaker, the government and other external forces in a naturally-occurring political speech setting. KW - gesture KW - intonation KW - spoken discourse KW - narrative structure KW - political speech KW - affect Y1 - 2005 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-8774 SN - 1866-4725 SN - 1614-4708 IS - 3 SP - 199 EP - 244 ER - TY - JOUR A1 - Teich, Elke A1 - Fankhauser, Peter T1 - Exploring lexical patterns in text BT - lexical cohesion analysis with WordNet JF - Interdisciplinary studies on information structure : ISIS ; working papers of the SFB 632 N2 - We present a system for the linguistic exploration and analysis of lexical cohesion in English texts. Using an electronic thesaurus-like resource, Princeton WordNet, and the Brown Corpus of English, we have implemented a process of annotating text with lexical chains and a graphical user interface for inspection of the annotated text. We describe the system and report on some sample linguistic analyses carried out using the combined thesaurus-corpus resource. Y1 - 2005 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-8685 SN - 1866-4725 SN - 1614-4708 IS - 2 SP - 129 EP - 145 ER - TY - JOUR A1 - Lüdeling, Anke T1 - Heterogeneity and standardization in data, use, and annotation BT - a diachronic corpus of german JF - Interdisciplinary studies on information structure : ISIS ; working papers of the SFB 632 N2 - This paper describes the standardization problems that come up in a diachronic corpus: it has to cope with differing standards with regard to diplomaticity, annotation, and header information. Such highly het-erogeneous texts must be standardized to allow for comparative re-search without (too much) loss of information. Y1 - 2005 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-8643 SN - 1866-4725 SN - 1614-4708 IS - 2 SP - 43 EP - 54 ER - TY - JOUR A1 - Kitagawa, Yoshihisa ED - Ishihara, Shinichiro ED - Petrova, Svetlana ED - Schwarz, Anne T1 - When we fail to question in Japanese JF - Interdisciplinary studies on information structure : ISIS ; working papers of the SFB 632 N2 - When we pay close attention to the prosody of Wh-questions in Japanese, we discover many novel and interesting empirical puzzles that would require us to devise a much finer syntactic component of grammar. This paper addresses the issues that pose some problems to such an elaborated grammar, and offers solutions, making an appeal to the information structure and sentence processing involved in the interpretation of interrogative and focus constructions. KW - focus KW - (implicit) prosody KW - information structure KW - processing KW - Wh-question Y1 - 2007 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-24481 SN - 1866-4725 SN - 1614-4708 VL - 9 SP - 29 EP - 64 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Tomioka, Satoshi ED - Ishihara, Shinichiro ED - Petrova, Svetlana ED - Schwarz, Anne T1 - Intervention effects in focus BT - from a Japanese point of view JF - Interdisciplinary studies on information structure : ISIS ; working papers of the SFB 632 N2 - The most recent trend in the studies of LF intervention effects makes crucial reference to focusing effects on the interveners, and this paper critically examines the representative analyses of the focus-based approach. While each analysis has its own merits and shortcomings, I argue that a pragmatic analysis that does not make appeal to syntactic configurations is better equipped to deal with many of the complex and delicate facts surrounding intervention effects. KW - Intervention Effect KW - Alternative Semantics KW - Whinterrogatives KW - Focus KW - Topic KW - Post-Focus Reduction Y1 - 2007 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-24502 SN - 1866-4725 SN - 1614-4708 VL - 9 SP - 97 EP - 118 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Kubozono, Haruo ED - Ishihara, Shinichiro ED - Petrova, Svetlana ED - Schwarz, Anne T1 - Focus and intonation in Japanese BT - Does focus trigger pitch reset? JF - Interdisciplinary studies on information structure : ISIS ; working papers of the SFB 632 N2 - This paper discusses how focus changes prosodic structure in Tokyo Japanese. It is generally believed that focus blocks the intonational process of downstep and causes a pitch reset. This paper presents experimental evidence against this traditional view by looking at the prosodic behavior of Wh words, which receive focus lexically in Japanese as in other languages. It is demonstrated, specifically, that the focused Wh element does not block downstep although it receives a much higher pitch than its preceding element. This suggests that presence of lexical focus does not trigger pitch reset in Japanese. KW - Focus KW - Intonation KW - Japanese KW - Pitch Reset KW - Downstep Y1 - 2007 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-24472 SN - 1866-4725 SN - 1614-4708 VL - 9 SP - 1 EP - 27 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Steinfath, Matthias A1 - Gärtner, Tanja A1 - Lisec, Jan A1 - Meyer, Rhonda Christiane A1 - Altmann, Thomas A1 - Willmitzer, Lothar A1 - Selbig, Joachim T1 - Prediction of hybrid biomass in Arabidopsis thaliana by selected parental SNP and metabolic markers JF - Theoretical and applied genetics : TAG ; international journal of plant breeding research N2 - A recombinant inbred line (RIL) population, derived from two Arabidopsis thaliana accessions, and the corresponding testcrosses with these two original accessions were used for the development and validation of machine learning models to predict the biomass of hybrids. Genetic and metabolic information of the RILs served as predictors. Feature selection reduced the number of variables (genetic and metabolic markers) in the models by more than 80% without impairing the predictive power. Thus, potential biomarkers have been revealed. Metabolites were shown to bear information on inherited macroscopic phenotypes. This proof of concept could be interesting for breeders. The example population exhibits substantial mid-parent biomass heterosis. The results of feature selection could therefore be used to shed light on the origin of heterosis. In this respect, mainly dominance effects were detected. KW - Quantitative Trait Locus KW - feature selection KW - Partial Little Square KW - recombinant inbred line KW - Quantitative Trait Locus analysis Y1 - 2009 U6 - https://doi.org/10.1007/s00122-009-1191-2 SN - 0040-5752 SN - 1432-2242 VL - 120 SP - 239 EP - 247 PB - Springer CY - Berlin ER - TY - JOUR A1 - Kempa, Stefan A1 - Hummel, Jan A1 - Schwemmer, Thorsten A1 - Pietzke, Matthias A1 - Strehmel, Nadine A1 - Wienkoop, Stefanie A1 - Kopka, Joachim A1 - Weckwerth, Wolfram T1 - An automated GCxGC-TOF-MS protocol for batch-wise extraction and alignment of mass isotopomer matrixes from differential C-13-labelling experiments : a case study for photoautotrophic-mixotrophic grown Chlamydomonas reinhardtii cells N2 - Two dimensional gas chromatography coupled to time-of-flight mass spectrometry (GCxGC-TOF-MS) is a promising technique to overcome limits of complex metabolome analysis using one dimensional GC-TOF-MS. Especially at the stage of data export and data mining, however, convenient procedures to cope with the complexity of GCxGC-TOF-MS data are still in development. Here, we present a high sample throughput protocol exploiting first and second retention index for spectral library search and subsequent construction of a high dimensional data matrix useful for statistical analysis. The method was applied to the analysis of 13 C-labelling experiments in the unicellular green alga Chlamydomonas reinhardtii. We developed a rapid sampling and extraction procedure for Chlamydomonas reinhardtii laboratory strain (CC503), a cell wall deficient mutant. By testing all published quenching protocols we observed dramatic metabolite leakage rates for certain metabolites. To circumvent metabolite leakage, samples were directly quenched and analyzed without separation of the medium. The growth medium was adapted to this rapid sampling protocol to avoid interference with GCxGC-TOF-MS analysis. To analyse batches of samples a new software tool, MetMax, was implemented which extracts the isotopomer matrix from stable isotope labelling experiments together with the first and second retention index (RI1 and RI2). To exploit RI1 and RI2 for metabolite identification we used the Golm metabolome database (GMD [1] with RI1/ RI2-reference spectra and new search algorithms. Using those techniques we analysed the dynamics of (CO2)-C-13 and C-13- acetate uptake in Chlamydomonas reinhardtii cells in two different steady states namely photoautotrophic and mixotrophic growth conditions. Y1 - 2009 UR - http://www3.interscience.wiley.com/cgi-bin/jhome/5007687 U6 - https://doi.org/10.1002/jobm.200800337 SN - 0233-111X ER - TY - JOUR A1 - Rowe, John Carlos T1 - Disease, culture, and transnationalism in the Americas JF - Mobilisierte Kulturen Y1 - 2011 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-57345 SN - 2192-3019 SN - 2192-3027 IS - 1 SP - 71 EP - 87 ER - TY - JOUR A1 - Benacka, Jan T1 - BubbleSort, SelectSort and InsertSort in Excel & Delphi BT - learning the Concepts in a Constructionist Way JF - Commentarii informaticae didacticae : (CID) N2 - A method is presented of acquiring the principles of three sorting algorithms through developing interactive applications in Excel. KW - spreadsheets KW - sorting KW - constructionism Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-64636 SN - 1868-0844 SN - 2191-1940 IS - 6 SP - 153 EP - 154 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Ragonis, Noa T1 - Problem-solving strategies must be taught implicitly JF - Commentarii informaticae didacticae : (CID) N2 - Problem solving is one of the central activities performed by computer scientists as well as by computer science learners. Whereas the teaching of algorithms and programming languages is usually well structured within a curriculum, the development of learners’ problem-solving skills is largely implicit and less structured. Students at all levels often face difficulties in problem analysis and solution construction. The basic assumption of the workshop is that without some formal instruction on effective strategies, even the most inventive learner may resort to unproductive trial-and-error problemsolving processes. Hence, it is important to teach problem-solving strategies and to guide teachers on how to teach their pupils this cognitive tool. Computer science educators should be aware of the difficulties and acquire appropriate pedagogical tools to help their learners gain and experience problem-solving skills. KW - Problem solving KW - Problem solving strategies KW - Teaching problem solving strategies Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-64645 SN - 1868-0844 SN - 2191-1940 IS - 6 SP - 155 EP - 157 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Sentance, Sue A1 - Hodges, Steve T1 - .NET Gadgeteer Workshop JF - Commentarii informaticae didacticae : (CID) Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-64654 SN - 1868-0844 SN - 2191-1940 IS - 6 SP - 159 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Berry, Carol A1 - Kusterer, Peter T1 - Using Teachers’ TryScience to support educators and improve teaching JF - Commentarii informaticae didacticae : (CID) N2 - The challenge is providing teachers with the resources they need to strengthen their instructions and better prepare students for the jobs of the 21st Century. Technology can help meet the challenge. Teachers’ Tryscience is a noncommercial offer, developed by the New York Hall of Science, TeachEngineering, the National Board for Professional Teaching Standards and IBM Citizenship to provide teachers with such resources. The workshop provides deeper insight into this tool and discussion of how to support teaching of informatics in schools. KW - science KW - teacher KW - collaboration KW - teaching material KW - instruction KW - lesson KW - social networking Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-64665 SN - 1868-0844 SN - 2191-1940 IS - 6 SP - 161 EP - 162 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Gujberová, Monika A1 - Tomcsányi, Peter T1 - Environments for programming in primary education JF - Commentarii informaticae didacticae : (CID) N2 - The aim of our article is to collect and present information about contemporary programming environments that are suitable for primary education. We studied the ways they implement (or do not implement) some programming concepts, the ways programs are represented and built in order to support young and novice programmers, as well as their suitability to allow different forms of sharing the results of pupils’ work. We present not only a short description of each considered environment and the taxonomy in the form of a table, but also our understanding and opinions on how and why the environments implement the same concepts and ideas in different ways and which concepts and ideas seem to be important to the creators of such environments. KW - Primary informatics KW - Programming environments for children KW - Comparing programming environments Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-64499 SN - 1868-0844 SN - 2191-1940 IS - 6 SP - 53 EP - 60 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Dagiene, Valentina A1 - Jevsikova, Tatjana A1 - Schule, Carsten A1 - Sentance, Sue A1 - Thota, Neena T1 - A comparison of current trends within computer science teaching in school in Germany and the UK JF - Commentarii informaticae didacticae : (CID) N2 - In the last two years, CS as a school subject has gained a lot of attention worldwide, although different countries have differing approaches to and experiences of introducing CS in schools. This paper reports on a study comparing current trends in CS at school, with a major focus on two countries, Germany and UK. A survey was carried out of a number of teaching professionals and experts from the UK and Germany with regard to the content and delivery of CS in school. An analysis of the quantitative data reveals a difference in foci in the two countries; putting this into the context of curricular developments we are able to offer interpretations of these trends and suggest ways in which curricula in CS at school should be moving forward. KW - CS Ed Research KW - ICT KW - CS at school KW - CS curriculum KW - topics KW - international comparison KW - international study Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-64504 SN - 1868-0844 SN - 2191-1940 IS - 6 SP - 63 EP - 75 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Gülbahar, Yasemin A1 - Ilkhan, Mustafa A1 - Kilis, Selcan A1 - Arslan, Okan T1 - Informatics education in Turkey BT - national ICT curriculum and teacher training at elementary level JF - Commentarii informaticae didacticae : (CID) N2 - This article is a summary of the work carried out by the Ministry of Education in Turkey, in terms of the development of a new ICT Curriculum, together with the e-Training of teachers who will play an important role in the forthcoming pilot study. Based on recent literature on the topic, the article starts by introducing the “F@tih Project”, a national project that aims to effectively integrate technology into schools. After assessing teachers’ and students’ ICT competencies, as defined internationally, the review continues with the proposed model for the e-training of teachers. Summarizing the process of development of the new ICT curriculum, researchers underline key points of the curriculum such as dimensions, levels and competencies. Then teachers’ e-training approaches, together with selected tools, are explained in line with the importance and stages of action research that will be used throughout the pilot implementation of the curriculum and e-training process. KW - informatics education KW - ICT curriculum KW - teacher training Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-64517 SN - 1868-0844 SN - 2191-1940 IS - 6 SP - 77 EP - 87 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Nakano, Yoshiaki A1 - Izutsu, Katsunobu T1 - The new course of study and a prospect of information studies education in Japan JF - Commentarii informaticae didacticae : (CID) N2 - Japan launched the new Course of Study in April 2012, which has been carried out in elementary schools and junior high schools. It will also be implemented in senior high schools from April 2013. This article presents an overview of the information studies education in the new Course of Study for K-12. Besides, the authors point out what role experts of informatics and information studies education should play in the general education centered around information studies that is meant to help people of the nation to lead an active, powerful, and flexible life until the satisfying end. KW - General subject “Information” KW - Course of Study KW - Scientific understanding of Information KW - Information Ethics Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-64522 SN - 1868-0844 SN - 2191-1940 IS - 6 SP - 89 EP - 96 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Lessner, Daniel T1 - The role of algorithm in general secondary education revisited JF - Commentarii informaticae didacticae : (CID) N2 - The traditional purpose of algorithm in education is to prepare students for programming. In our effort to introduce the practically missing computing science into Czech general secondary education, we have revisited this purpose.We propose an approach, which is in better accordance with the goals of general secondary education in Czechia. The importance of programming is diminishing, while recognition of algorithmic procedures and precise (yet concise) communication of algorithms is gaining importance. This includes expressing algorithms in natural language, which is more useful for most of the students than programming. We propose criteria to evaluate such descriptions. Finally, an idea about the limitations is required (inefficient algorithms, unsolvable problems, Turing’s test). We describe these adjusted educational goals and an outline of the resulting course. Our experience with carrying out the proposed intentions is satisfactory, although we did not accomplish all the defined goals. KW - computing science education KW - general secondary education KW - mandatory computer science foundations KW - concept of algorithm Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-64534 SN - 1868-0844 SN - 2191-1940 IS - 6 SP - 99 EP - 110 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Reffay, Christophe A1 - Miled, Mahdi A1 - Ortiz, Pascal A1 - Février, Loic T1 - An epistemic hypermedia to learn python as a resource for an introductory course for algorithmic in France JF - Commentarii informaticae didacticae : (CID) N2 - We launched an original large-scale experiment concerning informatics learning in French high schools. We are using the France-IOI platform to federate resources and share observation for research. The first step is the implementation of an adaptive hypermedia based on very fine grain epistemic modules for Python programming learning. We define the necessary traces to be built in order to study the trajectories of navigation the pupils will draw across this hypermedia. It may be browsed by pupils either as a course support, or an extra help to solve the list of exercises (mainly for algorithmics discovery). By leaving the locus of control to the learner, we want to observe the different trajectories they finally draw through our system. These trajectories may be abstracted and interpreted as strategies and then compared for their relative efficiency. Our hypothesis is that learners have different profiles and may use the appropriate strategy accordingly. This paper presents the research questions, the method and the expected results. KW - Adaptive hypermedia KW - Navigation KW - Programming learning KW - Pytho n KW - Trajectories Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-64545 SN - 1868-0844 SN - 2191-1940 IS - 6 SP - 111 EP - 118 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Grgurina, Nataša T1 - Computational thinking in Dutch secondary education JF - Commentarii informaticae didacticae : (CID) N2 - We shall examine the Pedagogical Content Knowledge (PCK) of Computer Science (CS) teachers concerning students’ Computational Thinking (CT) problem solving skills within the context of a CS course in Dutch secondary education and thus obtain an operational definition of CT and ascertain appropriate teaching methodology. Next we shall develop an instrument to assess students’ CT and design a curriculum intervention geared toward teaching and improving students’ CT problem solving skills and competences. As a result, this research will yield an operational definition of CT, knowledge about CT PCK, a CT assessment instrument and teaching materials and accompanying teacher instructions. It shall contribute to CS teacher education, development of CT education and to education in other (STEM) subjects where CT plays a supporting role, both nationally and internationally. KW - computational thinking KW - situated learning KW - engaged computing KW - computer science Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-64556 SN - 1868-0844 SN - 2191-1940 IS - 6 SP - 119 EP - 123 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Weise, Martin T1 - A model for teaching informatics to German secondary school students in English-language bilingual education JF - Commentarii informaticae didacticae : (CID) N2 - Informatics as a school subject has been virtually absent from bilingual education programs in German secondary schools. Most bilingual programs in German secondary education started out by focusing on subjects from the field of social sciences. Teachers and bilingual curriculum experts alike have been regarding those as the most suitable subjects for bilingual instruction – largely due to the intercultural perspective that a bilingual approach provides. And though one cannot deny the gain that ensues from an intercultural perspective on subjects such as history or geography, this benefit is certainly not limited to social science subjects. In consequence, bilingual curriculum designers have already begun to include other subjects such as physics or chemistry in bilingual school programs. It only seems a small step to extend this to informatics. This paper will start out by addressing potential benefits of adding informatics to the range of subjects taught as part of English-language bilingual programs in German secondary education. In a second step it will sketch out a methodological (= didactical) model for teaching informatics to German learners through English. It will then provide two items of hands-on and tested teaching material in accordance with this model. The discussion will conclude with a brief outlook on the chances and prerequisites of firmly establishing informatics as part of bilingual school curricula in Germany. Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-64568 SN - 1868-0844 SN - 2191-1940 IS - 6 SP - 127 EP - 137 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Bellettini, Carlo A1 - Lonati, Violetta A1 - Malchiodi, Dario A1 - Monga, Mattia A1 - Morpurgo, Anna A1 - Torelli, Mauro T1 - What you see is what you have in mind BT - constructing mental models for formatted text processing JF - Commentarii informaticae didacticae : (CID) N2 - In this paper we report on our experiments in teaching computer science concepts with a mix of tangible and abstract object manipulations. The goal we set ourselves was to let pupils discover the challenges one has to meet to automatically manipulate formatted text. We worked with a group of 25 secondary school pupils (9-10th grade), and they were actually able to “invent” the concept of mark-up language. From this experiment we distilled a set of activities which will be replicated in other classes (6th grade) under the guidance of maths teachers. Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-64612 SN - 1868-0844 SN - 2191-1940 IS - 6 SP - 139 EP - 147 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Planteu, Lukas A1 - Standl, Bernhard A1 - Grossmann, Wilfried A1 - Neuwirth, Erich T1 - Integrating school practice in Austrian teacher education JF - Commentarii informaticae didacticae : (CID) N2 - We present a concept of better integration of practical teaching in student teacher education in Computer Science. As an introduction to the workshop different possible scenarios are discussed on the basis of examples. Afterwards workshop participants will have the opportunity to discuss the application of the aconcepts in other settings. Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-64628 SN - 1868-0844 SN - 2191-1940 IS - 6 SP - 151 EP - 152 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Linck, Barbara T1 - Test items for and misconceptions of competences in the domain of logic programming JF - Commentarii informaticae didacticae : (CID) N2 - Development of competence-oriented curricula is still an important theme in informatics education. Unfortunately informatics curricula, which include the domain of logic programming, are still input-orientated or lack detailed competence descriptions. Therefore, the development of competence model and of learning outcomes' descriptions is essential for the learning process in this domain. A prior research developed both. The next research step is to formulate test items to measure the described learning outcomes. This article describes this procedure and exemplifies test items. It also relates a test in school to the items and shows which misconceptions and typical errors are important to discuss in class. The test result can also confirm or disprove the competence model. Therefore, this school test is important for theoretical research as well as for the concrete planning of lessons. Quantitative analysis in school is important for evaluation and improvement of informatics education. KW - competence KW - test items KW - misconceptions KW - informatics in upper secondary education KW - logic programming Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-64461 SN - 1868-0844 SN - 2191-1940 IS - 6 SP - 25 EP - 34 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Kim, Seungyon A1 - Park, Seongbin T1 - Teaching NP completeness in secondary schools JF - Commentarii informaticae didacticae : (CID) N2 - In this paper, we show how the theory of NP completeness can be introduced to students in secondary schools. The motivation of this research is that although there are difficult issues that require technical backgrounds, students are already familiar with demanding computational problems through games such as Sudoku or Tetris. Our intention is to bring together important concepts in the theory of NP completeness in such a way that students in secondary schools can easily understand them. This is part of our ongoing research about how to teach fundamental issues in Computer Science in secondary schools. We discuss what needs to be taught in which sequence in order to introduce ideas behind NP completeness to students without technical backgrounds. Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-64476 SN - 1868-0844 SN - 2191-1940 IS - 6 SP - 35 EP - 38 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Vaníček, Jiří T1 - Introducing topics from informatics into primary school curricula BT - how do teachers take it? JF - Commentarii informaticae didacticae : (CID) N2 - The process of introducing compulsory ICT education at primary school level in the Czech Republic should be completed next year. Programming and Information, two topics from the basics of computer science have been included in a new textbook. The question is whether the new chapters of the textbook are comprehensible for primary school teachers, who have undergone no training in computer science. The paper reports on a pilot verification project in which pre-service primary school teachers were trained to teach these informatics topics. KW - primary school KW - informatics curricula KW - teacher education Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-64482 SN - 1868-0844 SN - 2191-1940 IS - 6 SP - 41 EP - 51 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Fuehrer, Felix N. A1 - Schlaad, Helmut T1 - ADMET polymerization of amino-acid-based diene JF - Macromolecular chemistry and physics N2 - 1,4-Di(homo)allyl-2,5-diketopiperazines are synthesized and polymerized via ADMET using the Hoveyda-Grubbs 2nd generation catalyst. The but-3-enylated diketopiperazine can be converted into unsaturated tertiary polyamide with molar mass of <3000 g mol(-1), whereas the allylated diketopiperazine cannot. Double-bond isomerization occurs regardless of whether or not benzoquinone is present. A polyesteramide with a higher molar mass of ca. 4800 g mol(-1) is obtained by the alternating copolymerization (ALTMET) of 1,4-di(but-3-enyl)-2,5-di ketopiperazine and ethylene glycol diacrylate. A post-polymerization modification of the poly(ester)amides via radical thiol-ene chemistry, however, fails. KW - acyclic diene metathesis (ADMET) polymerization KW - amino acids KW - diketopiperazine KW - metathesis KW - step-growth polymerization Y1 - 2014 U6 - https://doi.org/10.1002/macp.201400166 SN - 1022-1352 SN - 1521-3935 VL - 215 IS - 22 SP - 2268 EP - 2273 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Prasad, Sushma A1 - Baier, Janina T1 - Tracking the impact of mid- to late Holocene climate change and anthropogenic activities on Lake Holzmaar using an updated Holocene chronology JF - Global and planetary change N2 - The mid- to late Holocene interval is characterised by a highly variable climate in response to a gradual change in orbital insolation. The seasonal impact of these changes on the Eifel Maar region is not yet well documented largely due to uncertainties about the completeness of this archive ("missing varves" in the well known Lake Holzmaar) and a limited understanding of the factors (e.g. temperature, precipitation) influencing the seasonality archived within the lamination/varves. In this study we approach these challenges from a different perspective. Using detailed microfacies investigations we: (1) demonstrate that the ambiguity about the "missing varves" is related to the climate induced complex biotic and abiotic laminations that led to mis-identification of varves; (2) use a combination of detailed microfacies investigations (varve structure, seasonality of biotic and abiotic signals), lamination quality, varve counts on multiple cores, published and new radiocarbon dates to develop a continuous master chronology based on the Bayesian modelling approach. The dates of major climate, volcanic, and archaeological event(s) determined using our model are in good agreement with the independently determined ages of the same events from other archives, confirming the accuracy of our age model; (3) test the sensitivity of the seasonal proxies to the available data on mid-Holocene changes in temperature and precipitation; (4) demonstrate that the changes in lake eutrophicity are correlative with temperature changes in NW Europe and probably triggered by solar variability; and (5) show that the early Iron Age onset of eutrophication in Lake Holzmaar was climate induced and began several decades before the impact of anthropogenic activity was seen in the form of intensified detrital erosion in the catchment area. Our work has implications for understanding the impact of climate change and anthropogenic activities on limnological systems. (C) 2014 Elsevier B.V. All rights reserved. KW - Lake Holzmaar KW - varves KW - microfacies KW - Bayesian modelling KW - Iron Age KW - Ulmener Maar Tephra Y1 - 2014 U6 - https://doi.org/10.1016/j.gloplacha.2014.08.020 SN - 0921-8181 SN - 1872-6364 VL - 122 SP - 251 EP - 264 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Gamba, Cristina A1 - Jones, Eppie R. A1 - Teasdale, Matthew D. A1 - McLaughlin, Russell L. A1 - González-Fortes, Gloria M. A1 - Mattiangeli, Valeria A1 - Domboroczki, Laszlo A1 - Kovari, Ivett A1 - Pap, Ildiko A1 - Anders, Alexandra A1 - Whittle, Alasdair A1 - Dani, Janos A1 - Raczky, Pal A1 - Higham, Thomas F. G. A1 - Hofreiter, Michael A1 - Bradley, Daniel G. A1 - Pinhasi, Ron T1 - Genome flux and stasis in a five millennium transect of European prehistory JF - Nature Communications N2 - The Great Hungarian Plain was a crossroads of cultural transformations that have shaped European prehistory. Here we analyse a 5,000-year transect of human genomes, sampled from petrous bones giving consistently excellent endogenous DNA yields, from 13 Hungarian Neolithic, Copper, Bronze and Iron Age burials including two to high (similar to 22x) and seven to similar to 1x coverage, to investigate the impact of these on Europe's genetic landscape. These data suggest genomic shifts with the advent of the Neolithic, Bronze and Iron Ages, with interleaved periods of genome stability. The earliest Neolithic context genome shows a European hunter-gatherer genetic signature and a restricted ancestral population size, suggesting direct contact between cultures after the arrival of the first farmers into Europe. The latest, Iron Age, sample reveals an eastern genomic influence concordant with introduced Steppe burial rites. We observe transition towards lighter pigmentation and surprisingly, no Neolithic presence of lactase persistence. Y1 - 2014 U6 - https://doi.org/10.1038/ncomms6257 SN - 2041-1723 VL - 5 PB - Nature Publ. Group CY - London ER - TY - JOUR A1 - Scheck-Wenderoth, Magdalena A1 - Cacace, Mauro A1 - Maystrenko, Yuriy Petrovich A1 - Cherubini, Yvonne A1 - Noack, Vera A1 - Kaiser, Bjoern Onno A1 - Sippel, Judith A1 - Bjoern, Lewerenz T1 - Models of heat transport in the Central European Basin System: Effective mechanisms at different scales JF - Marine and petroleum geology N2 - Understanding heat transport in sedimentary basins requires an assessment of the regional 3D heat distribution and of the main physical mechanisms responsible for the transport of heat. We review results from different 3D numerical simulations of heat transport based on 3D basin models of the Central European Basin System (CEBS). Therefore we compare differently detailed 3D structural models of the area, previously published individually, to assess the influence of (1) different configurations of the deeper lithosphere, (2) the mechanism of heat transport considered and (3) large faults dissecting the sedimentary succession on the resulting thermal field and groundwater flow. Based on this comparison we propose a modelling strategy linking the regional and lithosphere-scale to the sub-basin and basin-fill scale and appropriately considering the effective heat transport processes. We find that conduction as the dominant mechanism of heat transport in sedimentary basins is controlled by the distribution of thermal conductivities, compositional and thickness variations of both the conductive and radiogenic crystalline crust as well as the insulating sediments and by variations in the depth to the thermal lithosphere-asthenosphere boundary. Variations of these factors cause thermal anomalies of specific wavelength and must be accounted for in regional thermal studies. In addition advective heat transport also exerts control on the thermal field on the regional scale. In contrast, convective heat transport and heat transport along faults is only locally important and needs to be considered for exploration on the reservoir scale. The general applicability of the proposed workflow makes it of interest for a broad range of application in geosciences including oil and gas exploration, geothermal utilization or carbon capture and sequestration issues. (C) 2014 Elsevier Ltd. All rights reserved. KW - 3D thermal model KW - Geothermal field KW - Sedimentary basin KW - Heat transport by conduction KW - Advection and convection KW - Central European Basin System Y1 - 2014 U6 - https://doi.org/10.1016/j.marpetgeo.2014.03.009 SN - 0264-8172 SN - 1873-4073 VL - 55 SP - 315 EP - 331 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Lehmann, Jascha A1 - Coumou, Dim A1 - Frieler, Katja A1 - Eliseev, Alexey V. A1 - Levermann, Anders T1 - Future changes in extratropical storm tracks and baroclinicity under climate change JF - Environmental research letters N2 - The weather in Eurasia, Australia, and North and South America is largely controlled by the strength and position of extratropical storm tracks. Future climate change will likely affect these storm tracks and the associated transport of energy, momentum, and water vapour. Many recent studies have analyzed how storm tracks will change under climate change, and how these changes are related to atmospheric dynamics. However, there are still discrepancies between different studies on how storm tracks will change under future climate scenarios. Here, we show that under global warming the CMIP5 ensemble of coupled climate models projects only little relative changes in vertically averaged mid-latitude mean storm track activity during the northern winter, but agree in projecting a substantial decrease during summer. Seasonal changes in the Southern Hemisphere show the opposite behaviour, with an intensification in winter and no change during summer. These distinct seasonal changes in northern summer and southern winter storm tracks lead to an amplified seasonal cycle in a future climate. Similar changes are seen in the mid-latitude mean Eady growth rate maximum, a measure that combines changes in vertical shear and static stability based on baroclinic instability theory. Regression analysis between changes in the storm tracks and changes in the maximum Eady growth rate reveal that most models agree in a positive association between the two quantities over mid-latitude regions. KW - storm tracks KW - baroclinicity KW - climate change Y1 - 2014 U6 - https://doi.org/10.1088/1748-9326/9/8/084002 SN - 1748-9326 VL - 9 IS - 8 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Jones, Eppie R. A1 - González-Fortes, Gloria M. A1 - Connell, Sarah A1 - Siska, Veronika A1 - Eriksson, Anders A1 - Martiniano, Rui A1 - McLaughlin, Russell L. A1 - Llorente, Marcos Gallego A1 - Cassidy, Lara M. A1 - Gamba, Cristina A1 - Meshveliani, Tengiz A1 - Bar-Yosef, Ofer A1 - Mueller, Werner A1 - Belfer-Cohen, Anna A1 - Matskevich, Zinovi A1 - Jakeli, Nino A1 - Higham, Thomas F. G. A1 - Currat, Mathias A1 - Lordkipanidze, David A1 - Hofreiter, Michael A1 - Manica, Andrea A1 - Pinhasi, Ron A1 - Bradley, Daniel G. T1 - Upper Palaeolithic genomes reveal deep roots of modern Eurasians JF - Nature Communications N2 - We extend the scope of European palaeogenomics by sequencing the genomes of Late Upper Palaeolithic (13,300 years old, 1.4-fold coverage) and Mesolithic (9,700 years old, 15.4-fold) males from western Georgia in the Caucasus and a Late Upper Palaeolithic (13,700 years old, 9.5-fold) male from Switzerland. While we detect Late Palaeolithic-Mesolithic genomic continuity in both regions, we find that Caucasus hunter-gatherers (CHG) belong to a distinct ancient clade that split from western hunter-gatherers similar to 45 kya, shortly after the expansion of anatomically modern humans into Europe and from the ancestors of Neolithic farmers similar to 25 kya, around the Last Glacial Maximum. CHG genomes significantly contributed to the Yamnaya steppe herders who migrated into Europe similar to 3,000 BC, supporting a formative Caucasus influence on this important Early Bronze age culture. CHG left their imprint on modern populations from the Caucasus and also central and south Asia possibly marking the arrival of Indo-Aryan languages. Y1 - 2015 U6 - https://doi.org/10.1038/ncomms9912 SN - 2041-1723 VL - 6 PB - Nature Publishing Group CY - London ER - TY - JOUR A1 - Dvornikov, Yury A1 - Leibman, Marina A1 - Heim, Birgit A1 - Bartsch, Annett A1 - Herzschuh, Ulrike A1 - Skorospekhova, Tatiana A1 - Fedorova, Irina A1 - Khomutov, Artem A1 - Widhalm, Barbara A1 - Gubarkov, Anatoly A1 - Rößler, Sebastian T1 - Terrestrial CDOM in lakes of Yamal Peninsula BT - Connection to lake and lake catchment properties JF - Remote Sensing N2 - In this study, we analyze interactions in lake and lake catchment systems of a continuous permafrost area. We assessed colored dissolved organic matter (CDOM) absorption at 440 nm (a(440)(CDOM)) and absorption slope (S300-500) in lakes using field sampling and optical remote sensing data for an area of 350 km(2) in Central Yamal, Siberia. Applying a CDOM algorithm (ratio of green and red band reflectance) for two high spatial resolution multispectral GeoEye-1 and Worldview-2 satellite images, we were able to extrapolate the a()(CDOM) data from 18 lakes sampled in the field to 356 lakes in the study area (model R-2 = 0.79). Values of a(440)(CDOM) in 356 lakes varied from 0.48 to 8.35 m(-1) with a median of 1.43 m(-1). This a()(CDOM) dataset was used to relate lake CDOM to 17 lake and lake catchment parameters derived from optical and radar remote sensing data and from digital elevation model analysis in order to establish the parameters controlling CDOM in lakes on the Yamal Peninsula. Regression tree model and boosted regression tree analysis showed that the activity of cryogenic processes (thermocirques) in the lake shores and lake water level were the two most important controls, explaining 48.4% and 28.4% of lake CDOM, respectively (R-2 = 0.61). Activation of thermocirques led to a large input of terrestrial organic matter and sediments from catchments and thawed permafrost to lakes (n = 15, mean a(440)(CDOM) = 5.3 m(-1)). Large lakes on the floodplain with a connection to Mordy-Yakha River received more CDOM (n = 7, mean a(440)(CDOM) = 3.8 m(-1)) compared to lakes located on higher terraces. KW - CDOM KW - lakes KW - lake catchments KW - permafrost KW - Yamal KW - remote sensing data Y1 - 2018 U6 - https://doi.org/10.3390/rs10020167 SN - 2072-4292 VL - 10 IS - 2 PB - MDPI CY - Basel ER - TY - JOUR A1 - Kotthoff, Lisa A1 - Lisec, Jan A1 - Schwerdtle, Tanja A1 - Koch, Matthias T1 - Prediction of transformation products of monensin by electrochemistry compared to microsomal assay and hydrolysis JF - Molecules N2 - The knowledge of transformation pathways and identification of transformation products (TPs) of veterinary drugs is important for animal health, food, and environmental matters. The active agent Monensin (MON) belongs to the ionophore antibiotics and is widely used as a veterinary drug against coccidiosis in broiler farming. However, no electrochemically (EC) generated TPs of MON have been described so far. In this study, the online coupling of EC and mass spectrometry (MS) was used for the generation of oxidative TPs. EC-conditions were optimized with respect to working electrode material, solvent, modifier, and potential polarity. Subsequent LC/HRMS (liquid chromatography/high resolution mass spectrometry) and MS/MS experiments were performed to identify the structures of derived TPs by a suspected target analysis. The obtained EC-results were compared to TPs observed in metabolism tests with microsomes and hydrolysis experiments of MON. Five previously undescribed TPs of MON were identified in our EC/MS based study and one TP, which was already known from literature and found by a microsomal assay, could be confirmed. Two and three further TPs were found as products in microsomal tests and following hydrolysis, respectively. We found decarboxylation, O-demethylation and acid-catalyzed ring-opening reactions to be the major mechanisms of MON transformation. KW - transformation products KW - monensin KW - veterinary drugs KW - electrochemistry KW - hydrolysis KW - LC/HRMS Y1 - 2019 U6 - https://doi.org/10.3390/molecules24152732 SN - 1420-3049 VL - 24 IS - 15 PB - MDPI CY - Basel ER - TY - JOUR A1 - Rancan, Fiorenza A1 - Volkmann, Hildburg A1 - Giulbudagian, Michael A1 - Schumacher, Fabian A1 - Stanko, Jessica Isolde A1 - Kleuser, Burkhard A1 - Blume-Peytavi, Ulrike A1 - Calderon, Marcelo A1 - Vogt, Annika T1 - Dermal Delivery of the High-Molecular-Weight Drug Tacrolimus by Means of Polyglycerol-Based Nanogels JF - Pharmaceutics : Molecular Diversity Preservation International N2 - Polyglycerol-based thermoresponsive nanogels (tNGs) have been shown to have excellent skin hydration properties and to be valuable delivery systems for sustained release of drugs into skin. In this study, we compared the skin penetration of tacrolimus formulated in tNGs with a commercial 0.1% tacrolimus ointment. The penetration of the drug was investigated in ex vivo abdominal and breast skin, while different methods for skin barrier disruption were investigated to improve skin permeability or simulate inflammatory conditions with compromised skin barrier. The amount of penetrated tacrolimus was measured in skin extracts by liquid chromatography tandem-mass spectrometry (LC-MS/MS), whereas the inflammatory markers IL-6 and IL-8 were detected by enzyme-linked immunosorbent assay (ELISA). Higher amounts of tacrolimus penetrated in breast as compared to abdominal skin or in barrier-disrupted as compared to intact skin, confirming that the stratum corneum is the main barrier for tacrolimus skin penetration. The anti-proliferative effect of the penetrated drug was measured in skin tissue/Jurkat cells co-cultures. Interestingly, tNGs exhibited similar anti-proliferative effects as the 0.1% tacrolimus ointment. We conclude that polyglycerol-based nanogels represent an interesting alternative to paraffin-based formulations for the treatment of inflammatory skin conditions. KW - tacrolimus formulation KW - nanogels KW - skin penetration KW - drug delivery KW - human excised skin KW - Jurkat cells Y1 - 2019 U6 - https://doi.org/10.3390/pharmaceutics11080394 SN - 1999-4923 VL - 11 IS - 8 PB - MDPI CY - Basel ER - TY - JOUR A1 - Pornsawad, Pornsarp A1 - Sapsakul, Nantawan A1 - Böckmann, Christine T1 - A modified asymptotical regularization of nonlinear ill-posed problems JF - Mathematics N2 - In this paper, we investigate the continuous version of modified iterative Runge–Kutta-type methods for nonlinear inverse ill-posed problems proposed in a previous work. The convergence analysis is proved under the tangential cone condition, a modified discrepancy principle, i.e., the stopping time T is a solution of ∥𝐹(𝑥𝛿(𝑇))−𝑦𝛿∥=𝜏𝛿+ for some 𝛿+>𝛿, and an appropriate source condition. We yield the optimal rate of convergence. KW - nonlinear operator KW - regularization KW - discrepancy principle KW - asymptotic method KW - optimal rate Y1 - 2019 U6 - https://doi.org/10.3390/math7050419 SN - 2227-7390 VL - 7 PB - MDPI CY - Basel, Schweiz ET - 5 ER - TY - JOUR A1 - Omane, Paul Okyere A1 - Höhle, Barbara T1 - Acquiring syntactic variability BT - The production of Wh-questions in children and adults speaking Akan JF - Frontiers in communication N2 - This paper investigates the predictions of the Derivational Complexity Hypothesis by studying the acquisition of wh-questions in 4- and 5-year-old Akan-speaking children in an experimental approach using an elicited production and an elicited imitation task. Akan has two types of wh-question structures (wh-in-situ and wh-ex-situ questions), which allows an investigation of children’s acquisition of these two question structures and their preferences for one or the other. Our results show that adults prefer to use wh-ex-situ questions over wh-in-situ questions. The results from the children show that both age groups have the two question structures in their linguistic repertoire. However, they differ in their preferences in usage in the elicited production task: while the 5-year-olds preferred the wh-in-situ structure over the wh-ex-situ structure, the 4-year-olds showed a selective preference for the wh-in-situ structure in who-questions. These findings suggest a developmental change in wh-question preferences in Akan-learning children between 4 and 5 years of age with a so far unobserved u-shaped developmental pattern. In the elicited imitation task, all groups showed a strong tendency to maintain the structure of in-situ and ex-situ questions in repeating grammatical questions. When repairing ungrammatical ex-situ questions, structural changes to grammatical in-situ questions were hardly observed but the insertion of missing morphemes while keeping the ex-situ structure. Together, our findings provide only partial support for the Derivational Complexity Hypothesis. KW - Akan KW - wh-questions KW - wh-in-situ KW - wh-ex-situ KW - derivational complexity KW - language acquisition Y1 - 2021 U6 - https://doi.org/10.3389/fcomm.2021.604951 SN - 2297-900X VL - 2021 PB - Frontiers Media CY - Lausanne, Schweiz ER - TY - JOUR A1 - Thonig, Richard A1 - Del Rio, Pablo A1 - Kiefer, Christoph A1 - Lazaro Touza, Lara A1 - Escribano, Gonzalo A1 - Lechon, Yolanda A1 - Spaeth, Leonhard A1 - Wolf, Ingo A1 - Lilliestam, Johan T1 - Does ideology influence the ambition level of climate and renewable energy policy? BT - Insights from four European countries JF - Energy sources, part B: economics, planning, and policy N2 - We investigate whether political ideology has an observable effect on decarbonization ambition, renewable power aims, and preferences for power system balancing technologies in four European countries. Based on the Energy Logics framework, we identify ideologically different transition strategies (state-centered, market-centered, grassroots-centered) contained in government policies and opposition party programs valid in 2019. We compare these policies and programs with citizen poll data. We find that ideology has a small effect: governments and political parties across the spectrum have similar, and relatively ambitious, decarbonization and renewables targets. This mirrors citizens' strong support for ambitious action regardless of their ideological self-description. However, whereas political positions on phasing out fossil fuel power are clear across the policy space, positions on phasing in new flexibility options to balance intermittent renewables are vague or non-existent. As parties and citizens agree on strong climate and renewable power aims, the policy ambition is likely to remain high, even if governments change. KW - political ideology KW - climate policy KW - energy policy KW - europe KW - european KW - Union KW - renewable energy KW - flexibility Y1 - 2020 U6 - https://doi.org/10.1080/15567249.2020.1811806 SN - 1556-7249 SN - 1556-7257 VL - 16 IS - 1 SP - 4 EP - 22 PB - Taylor & Francis Group CY - Philadelphia ER -