TY - JOUR A1 - Jülisch, Bernd-Rüdiger A1 - Wagner, Christine T1 - Alltagsprobleme, Lebenswünsche und Zukunftsbefürchtungen Ost- und Westberliner Schüler JF - LLF-Berichte / Universität Potsdam, Zentrum für Lehrerbildung Y1 - 1992 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-4351 SN - 0945-294X VL - 4b ER - TY - JOUR A1 - Rochlitzer, Niels A1 - Klein, Armin A1 - Ebersbach, Lydia A1 - Konietzka, Attila A1 - Weingarten, Christine A1 - Karrasch, Arne A1 - Winter, Jean-Pierre A1 - Wagner, Jens A1 - Reininghaus, Moritz A1 - Resch-Esser, Ursula A1 - Pufal, Nadine A1 - Räder, Andy T1 - Portal = Nach dem Urteil: Diskussion um Studiengebühren BT - Die Potsdamer Universitätszeitung N2 - Aus dem Inhalt: - Nach dem Urteil: Diskussion um Studiengebühren - Die Zukunft lernt im Kindergarten - Krieg im Klassenzimmer - Mittelalterhistoriker und die Bischofsburg Ziesar T3 - Portal: Das Potsdamer Universitätsmagazin - 04-06/2005 Y1 - 2005 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-439880 SN - 1618-6893 IS - 04-06/2005 ER - TY - BOOK A1 - Klose, Dagmar A1 - Nolde, Bettina A1 - Eichholz, Nicole A1 - Nolde, Bettina A1 - Engelland, Christian A1 - Kroggel, Petra A1 - Kunde, Christine A1 - Pirska, Maya A1 - Stähr, Anne A1 - Flechsig, Thomas A1 - Lehmann, Andrea A1 - Petersen, Anne A1 - Siekmann, Katja A1 - Bielick, Jakob A1 - Skerra, Arne A1 - Bonnet, Florian A1 - Klemmt, Gregor A1 - Wagner, Anne A1 - Müller, Andreas A1 - Schurmann, Angela ED - Klose, Dagmar T1 - Die Grundlegung der modernen Welt in der Antike : Lehrerhandreiche für den Geschichtsunterricht nach neuem Rahmenlehrplan für die Sekundarstufe II Berlin-Brandenburg N2 - Ein neues Ziel-Inhalts-Konzept des Rahmenlehrplans nimmt in dieser Lehrerhandreiche Gestalt an. Fachwissenschaftliche und didaktische Instruktionen sowie ein ideenreicher Arbeitsteil (Materialien und Aufgaben) helfen bei der Unterrichtsvorbereitung. Aus dem Inhalt: - ein integratives Antike-Projekt untersucht Möglichkeiten und Grenzen gesellschaftlicher Teilhabe in Athen und der römischen Republik; - Augustus und Alexander als Zentralgestalten universaler Monarchie und Reichsbildung werden in der biografischen Rekonstruktion und im historischen Kontext lebendig; - das Thema Erinnerungskultur in der Antike und heute verweist auf Grundprobleme der Geschichtskultur; - Anregungen zur Arbeit mit dem Spielfilm „Alexander“ als historische Quelle führen an rezeptionsgeschichtliche und medienspezifische Aspekte historischen Lernens heran T3 - Perspektiven historischen Denkens und Lernens - 3 KW - Antike im Geschichtsunterricht KW - Geschichtskultur KW - Handlungsorientierung Y1 - 2008 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-15298 SN - 978-3-939469-96-4 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Wagner, Christine A1 - Sydow, Hubert T1 - Entwicklung und Sozialisation von Jugendlichen vor und nach der Vereinigung Deutschlands Y1 - 1996 ER - TY - JOUR A1 - Huang, Zirui A1 - Iv, Henry (Hap) Davis A1 - Yue, Qiang A1 - Wiebking, Christine A1 - Duncan, Niall W. A1 - Zhang, Jianfeng A1 - Wagner, Nils-Frederic A1 - Wolff, Annemarie A1 - Northoff, Georg T1 - Increase in glutamate/glutamine concentration in the medial prefrontal cortex during mental imagery: A combined functional mrs and fMRI study JF - Human brain mapping : a journal devoted to functional neuroanatomy and neuroimaging N2 - Recent functional magnetic resonance spectroscopy (fMRS) studies have shown changes in glutamate/glutamine (Glx) concentrations between resting-state and active-task conditions. However, the types of task used have been limited to sensory paradigms, and the regions from which Glx concentrations have been measured limited to sensory ones. This leaves open the question as to whether the same effect can be seen in higher-order brain regions during cognitive tasks. Cortical midline structures, especially the medial prefrontal cortex (MPFC), have been suggested to be involved in various such cognitive tasks. We, therefore set out to use fMRS to investigate the dynamics of Glx concentrations in the MPFC between resting-state and mental imagery task conditions. The auditory cortex was used as a control region. In addition, functional magnetic resonance imaging was used to explore task-related neural activity changes. The mental imagery task consisted of imagining swimming and was applied to a large sample of healthy participants (n=46). The participants were all competitive swimmers, ensuring proficiency in mental-swimming. Glx concentrations in the MPFC increased during the imagery task, as compared to resting-state periods preceding and following the task. These increases mirror BOLD activity changes in the same region during the task. No changes in either Glx concentrations or BOLD activity were seen in the auditory cortex. These findings contribute to our understanding of the biochemical basis of generating or manipulating mental representations and the MPFC's role in this. Hum Brain Mapp 36:3204-3212, 2015. (c) 2015 Wiley Periodicals, Inc. KW - medial prefrontal cortex KW - glutamate KW - glutamine KW - magnetic resonance spectroscopy KW - functional magnetic resonance imaging KW - mental imagery Y1 - 2015 U6 - https://doi.org/10.1002/hbm.22841 SN - 1065-9471 SN - 1097-0193 VL - 36 IS - 8 SP - 3204 EP - 3212 PB - Wiley-Blackwell CY - Hoboken ER - TY - JOUR A1 - Sánchez, Alba A1 - Thomas, Christine A1 - Deeken, Friederike A1 - Wagner, Sören A1 - Klöppel, Stefan A1 - Kentischer, Felix A1 - von Arnim, Chrstine A. F. A1 - Denkinger, Michael A1 - Conzelmann, Lars O. A1 - Biermann-Stallwitz, Janine A1 - Joos, Stefanie A1 - Sturm, Heidrun A1 - Metz, Brigitte A1 - Auer, Ramona A1 - Skrobik, Yoanna A1 - Eschweiler, Gerhard W. A1 - Rapp, Michael Armin T1 - Patient safety, cost-effectiveness, and quality of life BT - reduction of delirium risk and postoperative cognitive dysfunction after elective procedures in older adults—study protocol for a stepped-wedge cluster randomized trial (PAWEL Study) JF - Trials N2 - Background Postoperative delirium is a common disorder in older adults that is associated with higher morbidity and mortality, prolonged cognitive impairment, development of dementia, higher institutionalization rates, and rising healthcare costs. The probability of delirium after surgery increases with patients’ age, with pre-existing cognitive impairment, and with comorbidities, and its diagnosis and treatment is dependent on the knowledge of diagnostic criteria, risk factors, and treatment options of the medical staff. In this study, we will investigate whether a cross-sectoral and multimodal intervention for preventing delirium can reduce the prevalence of delirium and postoperative cognitive decline (POCD) in patients older than 70 years undergoing elective surgery. Additionally, we will analyze whether the intervention is cost-effective. Methods The study will be conducted at five medical centers (with two or three surgical departments each) in the southwest of Germany. The study employs a stepped-wedge design with cluster randomization of the medical centers. Measurements are performed at six consecutive points: preadmission, preoperative, and postoperative with daily delirium screening up to day 7 and POCD evaluations at 2, 6, and 12 months after surgery. Recruitment goals are to enroll 1500 patients older than 70 years undergoing elective operative procedures (cardiac, thoracic, vascular, proximal big joints and spine, genitourinary, gastrointestinal, and general elective surgery procedures. Discussion Results of the trial should form the basis of future standards for preventing delirium and POCD in surgical wards. Key aims are the improvement of patient safety and quality of life, as well as the reduction of the long-term risk of conversion to dementia. Furthermore, from an economic perspective, we expect benefits and decreased costs for hospitals, patients, and healthcare insurances. Trial registration German Clinical Trials Register, DRKS00013311. Registered on 10 November 2017. KW - Cross-sectoral care KW - Delirium prevention KW - Postoperative cognitive dysfunction KW - Dementia KW - Older patients KW - Elective surgery KW - Quality of life KW - Cost-effectiveness Y1 - 2019 U6 - https://doi.org/10.1186/s13063-018-3148-8 SN - 1468-6694 SN - 1745-6215 SN - 1468-6708 VL - 20 IS - 71 PB - BioMed Central CY - London ER - TY - GEN A1 - Sánchez, Alba A1 - Thomas, Christine A1 - Deeken, Friederike A1 - Wagner, Sören A1 - Klöppel, Stefan A1 - Kentischer, Felix A1 - von Arnim, Chrstine A. F. A1 - Denkinger, Michael A1 - Conzelmann, Lars O. A1 - Biermann-Stallwitz, Janine A1 - Joos, Stefanie A1 - Sturm, Heidrun A1 - Metz, Brigitte A1 - Auer, Ramona A1 - Skrobik, Yoanna A1 - Eschweiler, Gerhard W. A1 - Rapp, Michael Armin T1 - Patient safety, cost-effectiveness, and quality of life BT - reduction of delirium risk and postoperative cognitive dysfunction after elective procedures in older adults—study protocol for a stepped-wedge cluster randomized trial (PAWEL Study) T2 - Postprints der Universität Potsdam Humanwissenschaftliche Reihe N2 - Background Postoperative delirium is a common disorder in older adults that is associated with higher morbidity and mortality, prolonged cognitive impairment, development of dementia, higher institutionalization rates, and rising healthcare costs. The probability of delirium after surgery increases with patients’ age, with pre-existing cognitive impairment, and with comorbidities, and its diagnosis and treatment is dependent on the knowledge of diagnostic criteria, risk factors, and treatment options of the medical staff. In this study, we will investigate whether a cross-sectoral and multimodal intervention for preventing delirium can reduce the prevalence of delirium and postoperative cognitive decline (POCD) in patients older than 70 years undergoing elective surgery. Additionally, we will analyze whether the intervention is cost-effective. Methods The study will be conducted at five medical centers (with two or three surgical departments each) in the southwest of Germany. The study employs a stepped-wedge design with cluster randomization of the medical centers. Measurements are performed at six consecutive points: preadmission, preoperative, and postoperative with daily delirium screening up to day 7 and POCD evaluations at 2, 6, and 12 months after surgery. Recruitment goals are to enroll 1500 patients older than 70 years undergoing elective operative procedures (cardiac, thoracic, vascular, proximal big joints and spine, genitourinary, gastrointestinal, and general elective surgery procedures. Discussion Results of the trial should form the basis of future standards for preventing delirium and POCD in surgical wards. Key aims are the improvement of patient safety and quality of life, as well as the reduction of the long-term risk of conversion to dementia. Furthermore, from an economic perspective, we expect benefits and decreased costs for hospitals, patients, and healthcare insurances. Trial registration German Clinical Trials Register, DRKS00013311. Registered on 10 November 2017. T3 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 535 KW - Cross-sectoral care KW - Delirium prevention KW - Postoperative cognitive dysfunction KW - Dementia KW - Older patients KW - Elective surgery KW - Quality of life KW - Cost-effectiveness Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-424883 SN - 1866-8364 IS - 535 ER -