TY - JOUR A1 - Sandau, Ingo A1 - Chaabene, Helmi A1 - Granacher, Urs T1 - Concurrent validity of barbell force measured from video-based barbell kinematics during the snatch in male elite weightlifters JF - PLOS ONE / Public Library of Science N2 - This study examined the concurrent validity of an inverse dynamic (force computed from barbell acceleration [reference method]) and a work-energy (force computed from work at the barbell [alternative method]) approach to measure the mean vertical barbell force during the snatch using kinematic data from video analysis. For this purpose, the acceleration phase of the snatch was analyzed in thirty male medal winners of the 2018 weightlifting World Championships (age: 25.2±3.1 years; body mass: 88.9±28.6 kg). Vertical barbell kinematics were measured using a custom-made 2D real-time video analysis software. Agreement between the two computational approaches was assessed using Bland-Altman analysis, Deming regression, and Pearson product-moment correlation. Further, principal component analysis in conjunction with multiple linear regression was used to assess whether individual differences related to the two approaches are due to the waveforms of the acceleration time-series data. Results indicated no mean difference (p > 0.05; d = −0.04) and an extremely large correlation (r = 0.99) between the two approaches. Despite the high agreement, the total error of individual differences was 8.2% (163.0 N). The individual differences can be explained by a multiple linear regression model (R2adj = 0.86) on principal component scores from the principal component analysis of vertical barbell acceleration time-series waveforms. Findings from this study indicate that the individual errors of force measures can be associated with the inverse dynamic approach. This approach uses vertical barbell acceleration data from video analysis that is prone to error. Therefore, it is recommended to use the work-energy approach to compute mean vertical barbell force as this approach did not rely on vertical barbell acceleration. KW - Acceleration KW - Linear regression analysis KW - Velocity KW - Principal component analysis KW - Kinematics KW - Motion KW - Scanning electron microscopy KW - Computer Software Y1 - 2021 U6 - https://doi.org/10.1371/journal.pone.0254705 SN - 1932-6203 VL - 16 IS - 7 PB - PLOS CY - San Francisco ER - TY - JOUR A1 - Delfan, Maryam A1 - Juybari, Raheleh Amadeh A1 - Gorgani-Firuzjaee, Sattar A1 - Nielsen, Jens Høiriis A1 - Delfan, Neda A1 - Laher, Ismail A1 - Saeidi, Ayoub A1 - Granacher, Urs A1 - Zouhal, Hassane T1 - High-Intensity Interval Training Improves Cardiac Function by miR-206 Dependent HSP60 Induction in Diabetic Rats JF - Frontiers in Cardiovascular Medicine N2 - Objective: A role for microRNAs is implicated in several biological and pathological processes. We investigated the effects of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on molecular markers of diabetic cardiomyopathy in rats. Methods: Eighteen male Wistar rats (260 ± 10 g; aged 8 weeks) with streptozotocin (STZ)-induced type 1 diabetes mellitus (55 mg/kg, IP) were randomly allocated to three groups: control, MICT, and HIIT. The two different training protocols were performed 5 days each week for 5 weeks. Cardiac performance (end-systolic and end-diastolic dimensions, ejection fraction), the expression of miR-206, HSP60, and markers of apoptosis (cleaved PARP and cytochrome C) were determined at the end of the exercise interventions. Results: Both exercise interventions (HIIT and MICT) decreased blood glucose levels and improved cardiac performance, with greater changes in the HIIT group (p < 0.001, η2: 0.909). While the expressions of miR-206 and apoptotic markers decreased in both training protocols (p < 0.001, η2: 0.967), HIIT caused greater reductions in apoptotic markers and produced a 20% greater reduction in miR-206 compared with the MICT protocol (p < 0.001). Furthermore, both training protocols enhanced the expression of HSP60 (p < 0.001, η2: 0.976), with a nearly 50% greater increase in the HIIT group compared with MICT. Conclusions: Our results indicate that both exercise protocols, HIIT and MICT, have the potential to reduce diabetic cardiomyopathy by modifying the expression of miR-206 and its downstream targets of apoptosis. It seems however that HIIT is even more effective than MICT to modulate these molecular markers. KW - diabetes KW - apoptosis KW - miRNAs KW - exercise KW - cardiomyopathy Y1 - 2022 U6 - https://doi.org/10.3389/fcvm.2022.927956 SN - 2297-055X VL - 9 SP - 1 EP - 11 PB - Frontiers CY - Lausanne, Schweiz ER - TY - JOUR A1 - Jafarnezhadgero, Amir Ali A1 - Shad, Morteza Madadi A1 - Majlesi, Mahdi A1 - Granacher, Urs T1 - A comparison of running kinetics in children with and without genu varus BT - A cross sectional study JF - PLoS ONE N2 - Introduction Varus knee alignment has been identified as a risk factor for the progression of medial knee osteoarthritis. However, the underlying mechanisms have not been elucidated yet in children. Thus, the aims of the present study were to examine differences in ground reaction forces, loading rate, impulses, and free moment values during running in children with and without genu varus. Methods Thirty-six boys aged 9–14 volunteered to participate in this study. They were divided in two age-matched groups (genu varus versus healthy controls). Body weight adjusted three dimensional kinetic data (Fx, Fy, Fz) were collected during running at preferred speed using two Kistler force plates for the dominant and non-dominant limb. Results Individuals with knee genu varus produced significantly higher (p = .01; d = 1.09; 95%) body weight adjusted ground reaction forces in the lateral direction (Fx) of the dominant limb compared to controls. On the non-dominant limb, genu varus patients showed significantly higher body weight adjusted ground reaction forces values in the lateral (p = .01; d = 1.08; 86%) and medial (p < .001; d = 1.55; 102%) directions (Fx). Further, genu varus patients demonstrated 55% and 36% greater body weight adjusted loading rates in the dominant (p < .001; d = 2.09) and non-dominant (p < .001; d = 1.02) leg, respectively. No significant between-group differences were observed for adjusted free moment values (p>.05). Discussion Higher mediolateral ground reaction forces and vertical loading rate amplitudes in boys with genu varus during running at preferred running speed may accelerate the development of progressive joint degeneration in terms of the age at knee osteoarthritis onset. Therefore, practitioners and therapists are advised to conduct balance and strength training programs to improve lower limb alignment and mediolateral control during dynamic movements. Y1 - 2017 U6 - https://doi.org/10.1371/journal.pone.0185057 SN - 1932-6203 VL - 12 IS - 9 PB - PLoS CY - Lawrence, Kan. ER - TY - JOUR A1 - Jafarnezhadgero, Amir Ali A1 - Anvari, Maryam A1 - Granacher, Urs T1 - Long-term effects of shoe mileage on ground reaction forces and lower limb muscle activities during walking in individuals with genu varus JF - Clinical biomechanics N2 - Background: Shoe mileage is an important factor that may influence the risk of sustaining injuries during walking. The aims of this study were to examine the effects of shoe mileage on ground reaction forces and activity of lower limb muscles during walking in genu varus individuals compared with controls. Methods: Fifteen healthy and 15 genu varus females received a new pair of running shoes. They were asked to wear these shoes over 6 months. Pre and post intervention, mechanical shoe testing was conducted and ground reaction forces and muscle activities of the right leg were recorded during walking at preferred gait speed. Findings: Significant group-by-time interactions were found for shoe stiffness, antero-posterior and vertical impact peak. We observed higher shoe stiffness and lower impact peaks after intervention in both groups with larger effect sizes in genu varus. Significant group-by-time interactions were identified for vastus medialis (loading phase) and rectus femoris (loading and push-off). For vastus medialis, significant decreases were found from pre-to-post during the loading phase in the control group. Rectus femoris activity was higher post intervention during the loading and push-off phases in both groups with larger effect sizes in genu varus. Interpretation: Our findings indicate that the observed changes in ground reaction forces are more prominent in genu varus individuals. Together with our findings on shoe stiffness, it seems appropriate to change running shoes after an intense wearing time of 6 months, particularly in genu varus individuals. KW - footwear KW - electromyography KW - loading rate KW - patients Y1 - 2020 U6 - https://doi.org/10.1016/j.clinbiomech.2020.01.006 SN - 0268-0033 SN - 1879-1271 VL - 73 SP - 55 EP - 62 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Hortobágyi, Tibor A1 - Lesinski, Melanie A1 - Gäbler, Martijn A1 - VanSwearingen, Jessie M. A1 - Malatesta, Davide A1 - Granacher, Urs T1 - Effects of three types of exercise interventions on healthy old adults’ gait speed BT - a systematic review and meta-analysis JF - Sports medicine N2 - Background: Habitual walking speed predicts many clinical conditions later in life, but it declines with age. However, which particular exercise intervention can minimize the age-related gait speed loss is unclear. Purpose: Our objective was to determine the effects of strength, power, coordination, and multimodal exercise training on healthy old adults' habitual and fast gait speed. Methods: We performed a computerized systematic literature search in PubMed and Web of Knowledge from January 1984 up to December 2014. Search terms included 'Resistance training', 'power training', 'coordination training', 'multimodal training', and 'gait speed (outcome term). Inclusion criteria were articles available in full text, publication period over past 30 years, human species, journal articles, clinical trials, randomized controlled trials, English as publication language, and subject age C65 years. The methodological quality of all eligible intervention studies was assessed using the Physiotherapy Evidence Database (PEDro) scale. We computed weighted average standardized mean differences of the intervention-induced adaptations in gait speed using a random-effects model and tested for overall and individual intervention effects relative to no-exercise controls. Results: A total of 42 studies (mean PEDro score of 5.0 +/- 1.2) were included in the analyses (2495 healthy old adults; age 74.2 years [64.4-82.7]; body mass 69.9 +/- 4.9 kg, height 1.64 +/- 0.05 m, body mass index 26.4 +/- 1.9 kg/m(2), and gait speed 1.22 +/- 0.18 m/s). The search identified only one power training study, therefore the subsequent analyses focused only on the effects of resistance, coordination, and multimodal training on gait speed. The three types of intervention improved gait speed in the three experimental groups combined (n = 1297) by 0.10 m/s (+/- 0.12) or 8.4 % (+/- 9.7), with a large effect size (ES) of 0.84. Resistance (24 studies; n = 613; 0.11 m/s; 9.3 %; ES: 0.84), coordination (eight studies, n = 198; 0.09 m/s; 7.6 %; ES: 0.76), and multimodal training (19 studies; n = 486; 0.09 m/s; 8.4 %, ES: 0.86) increased gait speed statistically and similarly. Conclusions: Commonly used exercise interventions can functionally and clinically increase habitual and fast gait speed and help slow the loss of gait speed or delay its onset. KW - resistance training KW - exercise intervention KW - gait speed KW - power training KW - mobility disability Y1 - 2015 U6 - https://doi.org/10.1007/s40279-015-0371-2 SN - 1179-2035 SN - 0112-1642 N1 - Erratum in: Sports Med. 2016 Mar;46(3):453. doi: 10.1007/s40279-016-0498-9. VL - 45 SP - 1627 EP - 1643 PB - Springer CY - Berlin ER - TY - JOUR A1 - Gäbler, Martijn A1 - Berberyan, Hermine S. A1 - Prieske, Olaf A1 - Elferink-Gemser, Marije Titia A1 - Hortobágyi, Tibor A1 - Warnke, Torsten A1 - Granacher, Urs T1 - Strength Training Intensity and Volume Affect Performance of Young Kayakers/Canoeists JF - Frontiers in physiology N2 - Purpose: The aim of this study was to compare the effects of moderate intensity, low volume (MILV) vs. low intensity, high volume (LIHV) strength training on sport-specific performance, measures of muscular fitness, and skeletal muscle mass in young kayakers and canoeists. Methods: Semi-elite young kayakers and canoeists (N = 40, 13 ± 0.8 years, 11 girls) performed either MILV (70–80% 1-RM, 6–12 repetitions per set) or LIHV (30–40% 1-RM, 60–120 repetitions per set) strength training for one season. Linear mixed-effects models were used to compare effects of training condition on changes over time in 250 and 2,000 m time trials, handgrip strength, underhand shot throw, average bench pull power over 2 min, and skeletal muscle mass. Both between- and within-subject designs were used for analysis. An alpha of 0.05 was used to determine statistical significance. Results: Between- and within-subject analyses showed that monthly changes were greater in LIHV vs. MILV for the 2,000 m time trial (between: 9.16 s, SE = 2.70, p < 0.01; within: 2,000 m: 13.90 s, SE = 5.02, p = 0.01) and bench pull average power (between: 0.021 W⋅kg–1, SE = 0.008, p = 0.02; within: 0.010 W⋅kg–1, SE = 0.009, p > 0.05). Training conditions did not affect other outcomes. Conclusion: Young sprint kayakers and canoeists benefit from LIHV more than MILV strength training in terms of 2,000 m performance and muscular endurance (i.e., 2 min bench pull power). KW - youth sports KW - water sports KW - exercise test KW - athletic performance KW - anthropometry Y1 - 2021 U6 - https://doi.org/10.3389/fphys.2021.686744 SN - 1664-042X VL - 12 SP - 1 EP - 10 PB - Frontiers Research Foundation CY - Lausanne, Schweiz ER - TY - JOUR A1 - Chaabene, Helmi A1 - Negra, Yassine A1 - Bouguezzi, Raja A1 - Capranica, Laura A1 - Franchini, Emerson A1 - Prieske, Olaf A1 - Hbacha, Hamdi A1 - Granacher, Urs T1 - Tests for the Assessment of Sport-Specific Performance in Olympic Combat Sports BT - A Systematic Review With Practical Recommendations JF - Frontiers in Physiology N2 - The regular monitoring of physical fitness and sport-specific performance is important in elite sports to increase the likelihood of success in competition. This study aimed to systematically review and to critically appraise the methodological quality, validation data, and feasibility of the sport-specific performance assessment in Olympic combat sports like amateur boxing, fencing, judo, karate, taekwondo, and wrestling. A systematic search was conducted in the electronic databases PubMed, Google-Scholar, and Science-Direct up to October 2017. Studies in combat sports were included that reported validation data (e.g., reliability, validity, sensitivity) of sport-specific tests. Overall, 39 studies were eligible for inclusion in this review. The majority of studies (74%) contained sample sizes <30 subjects. Nearly, 1/3 of the reviewed studies lacked a sufficient description (e.g., anthropometrics, age, expertise level) of the included participants. Seventy-two percent of studies did not sufficiently report inclusion/exclusion criteria of their participants. In 62% of the included studies, the description and/or inclusion of a familiarization session (s) was either incomplete or not existent. Sixty-percent of studies did not report any details about the stability of testing conditions. Approximately half of the studies examined reliability measures of the included sport-specific tests (intraclass correlation coefficient [ICC] = 0.43–1.00). Content validity was addressed in all included studies, criterion validity (only the concurrent aspect of it) in approximately half of the studies with correlation coefficients ranging from r = −0.41 to 0.90. Construct validity was reported in 31% of the included studies and predictive validity in only one. Test sensitivity was addressed in 13% of the included studies. The majority of studies (64%) ignored and/or provided incomplete information on test feasibility and methodological limitations of the sport-specific test. In 28% of the included studies, insufficient information or a complete lack of information was provided in the respective field of the test application. Several methodological gaps exist in studies that used sport-specific performance tests in Olympic combat sports. Additional research should adopt more rigorous validation procedures in the application and description of sport-specific performance tests in Olympic combat sports. KW - martial arts KW - validity KW - sensitivity KW - methodological quality KW - specific assessment Y1 - 2018 U6 - https://doi.org/10.3389/fphys.2018.00386 SN - 1664-042X VL - 9 SP - 1 EP - 18 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Zinke, Fridolin A1 - Warnke, Torsten A1 - Gäbler, Martijn A1 - Granacher, Urs T1 - Effects of Isokinetic Training on Trunk Muscle Fitness and Body Composition in World-Class Canoe Sprinters JF - Frontiers in Physiology N2 - In canoe sprint, the trunk muscles play an important role in stabilizing the body in an unstable environment (boat) and in generating forces that are transmitted through the shoulders and arms to the paddle for propulsion of the boat. Isokinetic training is well suited for sports in which propulsion is generated through water resistance due to similarities in the resistive mode. Thus, the purpose of this study was to determine the effects of isokinetic training in addition to regular sport-specific training on trunk muscular fitness and body composition in world-class canoeists and to evaluate associations between trunk muscular fitness and canoe-specific performance. Nine world-class canoeists (age: 25.6 ± 3.3 years; three females; four world champions; three Olympic gold medalists) participated in an 8-week progressive isokinetic training with a 6-week block “muscle hypertrophy” and a 2-week block “muscle power.” Pre- and post-tests included the assessment of peak isokinetic torque at different velocities in concentric (30 and 140∘s-1) and eccentric (30 and 90∘s-1) mode, trunk muscle endurance, and body composition (e.g., body fat, segmental lean mass). Additionally, peak paddle force was assessed in the flume at a water current of 3.4 m/s. Significant pre-to-post increases were found for peak torque of the trunk rotators at 30∘s-1 (p = 0.047; d = 0.4) and 140∘s-1 (p = 0.014; d = 0.7) in concentric mode. No significant pre-to-post changes were detected for eccentric trunk rotator torque, trunk muscle endurance, and body composition (p > 0.148). Significant medium-to-large correlations were observed between concentric trunk rotator torque but not trunk muscle endurance and peak paddle force, irrespective of the isokinetic movement velocity (all r ≥ 0.886; p ≤ 0.008). Isokinetic trunk rotator training is effective in improving concentric trunk rotator strength in world-class canoe sprinters. It is recommended to progressively increase angular velocity from 30∘s-1 to 140∘s-1 over the course of the training period. KW - peak torque KW - canoe racing KW - core strength KW - sport-specific performance KW - elite athletes Y1 - 2019 U6 - https://doi.org/10.3389/fphys.2019.00021 SN - 1664-042X VL - 10 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Brini, Seifeddine A1 - Ben Abderrahman, Abderraouf A1 - Clark, Cain C. T. A1 - Zouita, Sghaeir A1 - Hackney, Anthony C. A1 - Govindasamy, Karuppasamy A1 - Granacher, Urs A1 - Zouhal, Hassane T1 - Sex-specific effects of small-sided games in basketball on psychometric and physiological markers during Ramadan intermittent fasting BT - a pilot study JF - BMC Sports Science, Medicine and Rehabilitation N2 - Background: We assessed the effects of gender, in association with a four-week small-sided games (SSGs) training program, during Ramadan intermitting fasting (RIF) on changes in psychometric and physiological markers in professional male and female basketball players. Methods: Twenty-four professional basketball players from the first Tunisian (Tunisia) division participated in this study. The players were dichotomized by sex (males [GM = 12]; females [GF = 12]). Both groups completed a 4 weeks SSGs training program with 3 sessions per week. Psychometric (e.g., quality of sleep, fatigue, stress, and delayed onset of muscle soreness [DOMS]) and physiological parameters (e.g., heart rate frequency, blood lactate) were measured during the first week (baseline) and at the end of RIF (post-test). Results: Post hoc tests showed a significant increase in stress levels in both groups (GM [− 81.11%; p < 0.001, d = 0.33, small]; GF [− 36,53%; p = 0.001, d = 0.25, small]). Concerning physiological parameters, ANCOVA revealed significantly lower heart rates in favor of GM at post-test (1.70%, d = 0.38, small, p = 0.002). Conclusions: Our results showed that SSGs training at the end of the RIF negatively impacted psychometric parameters of male and female basketball players. It can be concluded that there are sex-mediated effects of training during RIF in basketball players, and this should be considered by researchers and practitioners when programing training during RIF. KW - Team sports KW - Stress levels KW - Recovery KW - Performance KW - Fatigue Y1 - 2021 U6 - https://doi.org/10.1186/s13102-021-00285-1 SN - 2052-1847 VL - 13 PB - BioMed Central CY - London ER - TY - JOUR A1 - Chaabene, Helmi A1 - Prieske, Olaf A1 - Moran, Jason A1 - Negra, Yassine A1 - Attia, Ahmed A1 - Granacher, Urs T1 - Effects of resistance training on Change-of-Direction speed in youth and young physically active and athletic adults: a systematic review with meta-analysis JF - Sports medicine : the world's premier sports medicine preview journal N2 - Background Change-of-direction (CoD) speed is a physical fitness attribute in many field-based team and individual sports. To date, no systematic review with meta-analysis available has examined the effects of resistance training (RT) on CoD speed in youth and adults. Objective To aggregate the effects of RT on CoD speed in youth and young physically active and athletic adults, and to identify the key RT programme variables for training prescription. Data sources A systematic literature search was conducted with PubMed, Web of Science, and Google Scholar, with no date restrictions, up to October 2019, to identify studies related to the effects of RT on CoD speed. Study Eligibility Criteria Only controlled studies with baseline and follow-up measures were included if they examined the effects of RT (i.e., muscle actions against external resistances) on CoD speed in healthy youth (8-18 years) and young physically active/athletic male or female adults (19-28 years). Study Appraisal and Synthesis Methods A random-effects model was used to calculate weighted standardised mean differences (SMD) between intervention and control groups. In addition, an independent single training factor analysis (i.e., RT frequency, intensity, volume) was undertaken. Further, to verify if any RT variable moderated effects on CoD speed, a multivariate random-effects meta-regression was conducted. The methodological quality of the included studies was assessed using the physiotherapy evidence database (PEDro) scale. Results Fifteen studies, comprising 19 experimental groups, were included. The methodological quality of the studies was acceptable with a median PEDro score of 6. There was a significant large effect size of RT on CoD speed across all studies (SMD = - 0.82 [- 1.14 to - 0.49]). Subgroup analyses showed large effect sizes on CoD speed in males (SMD = - 0.95) contrasting with moderate improvements in females (SMD = - 0.60). There were large effect sizes on CoD speed in children (SMD = - 1.28) and adolescents (SMD = - 1.21) contrasting with moderate effects in adults (SMD = - 0.63). There was a moderate effect in elite athletes (SMD = - 0.69) contrasting with a large effect in subelite athletes (SMD = - 0.86). Differences between subgroups were not statistically significant. Similar improvements were observed regarding the effects of independently computed training variables. In terms of RT frequency, our results indicated that two sessions per week induced large effects on CoD speed (SMD = - 1.07) while programmes with three sessions resulted in moderate effects (SMD = - 0.53). For total training intervention duration, we observed large effects for <= 8 weeks (SMD = - 0.81) and > 8 weeks (SMD = - 0.85). For single session duration, we found large effects for <= 30 min and >= 45 min (both SMD = - 1.00). In terms of number of training sessions, we identified large effects for <= 16 sessions (SMD = - 0.83) and > 16 sessions (SMD = - 0.81). For training intensity, we found moderate effects for light-to-moderate (SMD = - 0.76) and vigorous-to-near maximal intensities (SMD = - 0.77). With regards to RT type, we observed large effects for free weights (SMD = - 0.99) and machine-based training (SMD = - 0.80). For combined free weights and machine-based training, moderate effects were identified (SMD = - 0.77). The meta-regression outcomes showed that none of the included training variables significantly predicted the effects of RT on CoD speed (R-2 = 0.00). Conclusions RT seems to be an effective means to improve CoD speed in youth and young physically active and athletic adults. Our findings indicate that the impact of RT on CoD speed may be more prominent in males than in females and in youth than in adults. Additionally, independently computed single factor analyses for different training variables showed that higher compared with lower RT intensities, frequencies, and volumes appear not to have an advantage on the magnitude of CoD speed improvements. In terms of RT type, similar improvements were observed following machine-based and free weights training. Y1 - 2020 U6 - https://doi.org/10.1007/s40279-020-01293-w SN - 0112-1642 SN - 1179-2035 VL - 50 IS - 8 SP - 1483 EP - 1499 PB - Springer CY - Berlin [u.a.] ER - TY - JOUR A1 - Prieske, Olaf A1 - Behrens, Martin A1 - Chaabene, Helmi A1 - Granacher, Urs A1 - Maffiuletti, Nicola A. T1 - Time to differentiate postactivation "potentiation" from "performance enhancement" in the strength and conditioning community JF - Sports medicine : the world's premier sports medicine preview journal N2 - Coaches and athletes in elite sports are constantly seeking to use innovative and advanced training strategies to efficiently improve strength/power performance in already highly-trained individuals. In this regard, high-intensity conditioning contractions have become a popular means to induce acute improvements primarily in muscle contractile properties, which are supposed to translate to subsequent power performances. This performance-enhancing physiological mechanism has previously been called postactivation potentiation (PAP). However, in contrast to the traditional mechanistic understanding of PAP that is based on electrically-evoked twitch properties, an increasing number of studies used the term PAP while referring to acute performance enhancements, even if physiological measures of PAP were not directly assessed. In this current opinion article, we compare the two main approaches (i.e., mechanistic vs. performance) used in the literature to describe PAP effects. We additionally discuss potential misconceptions in the general use of the term PAP. Studies showed that mechanistic and performance-related PAP approaches have different characteristics in terms of the applied research field (basic vs. applied), effective conditioning contractions (e.g., stimulated vs. voluntary), verification (lab-based vs. field tests), effects (twitch peak force vs. maximal voluntary strength), occurrence (consistent vs. inconsistent), and time course (largest effect immediately after vs. similar to 7 min after the conditioning contraction). Moreover, cross-sectional studies revealed inconsistent and trivial-to-large-sized associations between selected measures of mechanistic (e.g., twitch peak force) vs. performance-related PAP approaches (e.g., jump height). In an attempt to avoid misconceptions related to the two different PAP approaches, we propose to use two different terms. Postactivation potentiation should only be used to indicate the increase in muscular force/torque production during an electrically-evoked twitch. In contrast, postactivation performance enhancement (PAPE) should be used to refer to the enhancement of measures of maximal strength, power, and speed following conditioning contractions. The implementation of this terminology would help to better differentiate between mechanistic and performance-related PAP approaches. This is important from a physiological point of view, but also when it comes to aggregating findings from PAP studies, e.g., in the form of meta-analyses, and translating these findings to the field of strength and conditioning. Y1 - 2020 U6 - https://doi.org/10.1007/s40279-020-01300-0 SN - 0112-1642 SN - 1179-2035 VL - 50 IS - 9 SP - 1559 EP - 1565 PB - Springer CY - Berlin [u.a.] ER - TY - JOUR A1 - Delfan, Maryam A1 - Juybari, Raheleh Amadeh A1 - Gorgani-Firuzjaee, Sattar A1 - Høiriis Nielsen, Jens A1 - Delfan, Neda A1 - Laher, Ismail A1 - Saeidi, Ayoub A1 - Granacher, Urs A1 - Zouhal, Hassane T1 - High-intensity interval training improves cardiac function by miR-206 dependent HSP60 induction in diabetic rats JF - Frontiers in cardiovascular medicine N2 - ObjectiveA role for microRNAs is implicated in several biological and pathological processes. We investigated the effects of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on molecular markers of diabetic cardiomyopathy in rats. MethodsEighteen male Wistar rats (260 +/- 10 g; aged 8 weeks) with streptozotocin (STZ)-induced type 1 diabetes mellitus (55 mg/kg, IP) were randomly allocated to three groups: control, MICT, and HIIT. The two different training protocols were performed 5 days each week for 5 weeks. Cardiac performance (end-systolic and end-diastolic dimensions, ejection fraction), the expression of miR-206, HSP60, and markers of apoptosis (cleaved PARP and cytochrome C) were determined at the end of the exercise interventions. ResultsBoth exercise interventions (HIIT and MICT) decreased blood glucose levels and improved cardiac performance, with greater changes in the HIIT group (p < 0.001, eta(2): 0.909). While the expressions of miR-206 and apoptotic markers decreased in both training protocols (p < 0.001, eta(2): 0.967), HIIT caused greater reductions in apoptotic markers and produced a 20% greater reduction in miR-206 compared with the MICT protocol (p < 0.001). Furthermore, both training protocols enhanced the expression of HSP60 (p < 0.001, eta(2): 0.976), with a nearly 50% greater increase in the HIIT group compared with MICT. ConclusionsOur results indicate that both exercise protocols, HIIT and MICT, have the potential to reduce diabetic cardiomyopathy by modifying the expression of miR-206 and its downstream targets of apoptosis. It seems however that HIIT is even more effective than MICT to modulate these molecular markers. KW - diabetes KW - apoptosis KW - miRNAs KW - exercise KW - cardiomyopathy Y1 - 2022 U6 - https://doi.org/10.3389/fcvm.2022.927956 SN - 2297-055X VL - 9 PB - Frontiers Media CY - Lausanne ER - TY - JOUR A1 - Chaabene, Helmi A1 - Negra, Yassine A1 - Moran, Jason A1 - Prieske, Olaf A1 - Sammoud, Senda A1 - Ramirez-Campillo, Rodrigo A1 - Granacher, Urs T1 - Plyometric training improves not only measures of linear speed, power, and change-of-direction speed but also repeated sprint ability in young female handball players JF - Journal of strength and conditioning research : the research journal of the NSCA N2 - This study examined the effects of an 8-week plyometric training (PT) program on components of physical fitness in young female handball players. Twenty-one female adolescent handball players were assigned to an experimental group (EG, n = 12; age = 15.9 +/- 0.2 years) or an active control group (CG, n = 9, age = 15.9 +/- 0.3 years). While EG performed plyometric exercises in replacement of some handball-specific drills, CG maintained the regular training schedule. Baseline and follow-up tests were performed for the assessment of linear speed (i.e., 5-, 10-, and 20-m time), change-of-direction (CoD) speed (i.e., T-test time), muscle power (i.e., countermovement jump [CMJ] height and reactive strength index [RSI]), and repeated sprint ability (RSA) (RSA total time [RSA(total)], RSA best time [RSA(best)], and RSA fatigue index [RSA(FI)]). Data were analyzed using magnitude-based inferences. Within-group analyses for the EG revealed moderate-to-large improvements for the 5-m (effect size [ES] = 0.81 [0.1-1.5]), 10-m sprint time (ES = 0.84 [0.1-1.5]), RSI (ES = 0.75 [0.1-1.4]), RSA(FI) (ES = 0.65 [0.0-1.3]), and T-test time (ES = 1.46 [0.7-2.2]). Trivial-to-small ES was observed for RSA(best) (ES = 0.18 [-0.5 to 0.9]), RSA(total) (ES = 0.45 [-0.2 to 1.1]), 20-m sprint time (ES = 0.56 [-0.1 to 1.2]), and CMJ height (ES = 0.57 [-0.1 to 1.3]). For the CG, within-group analyses showed a moderate performance decline for T-test time (ES = -0.71 [-1.5 to 0.1]), small decreases for 5-m sprint time (ES = -0.46 [-1.2 to 0.3]), and a trivial decline for 10-m (ES = -0.10 [-0.9 to 0.7]) and 20-m sprint times (ES = -0.16 [-0.9 to 0.6]), RSA(total) (ES = 0.0 [-0.8 to 0.8]), and RSA(best) (ES = -0.20 [-0.9 to 0.6]). The control group achieved trivial-to-small improvements for CMJ height (ES = 0.10 [-0.68 to 0.87]) and RSI (ES = 0.30 [-0.5 to 1.1]). In conclusion, a short-term in-season PT program, in replacement of handball-specific drills, is effective in improving measures of physical fitness (i.e., linear/CoD speed, jumping, and RSA) in young female handball players. KW - stretch-shortening cycle KW - physical fitness KW - young athletes Y1 - 2021 U6 - https://doi.org/10.1519/JSC.0000000000003128 SN - 1064-8011 SN - 1533-4287 VL - 35 IS - 8 SP - 2230 EP - 2235 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - JOUR A1 - Negra, Yassine A1 - Chaabene, Helmi A1 - Sammoud, Senda A1 - Bouguezzi, Raja A1 - Mkaouer, Bessem A1 - Hachana, Younes A1 - Granacher, Urs T1 - EFFECTS OF PLYOMETRIC TRAINING ON COMPONENTS OF PHYSICAL FITNESS IN PREPUBERAL MALE SOCCER ATHLETES: THE ROLE OF SURFACE INSTABILITY JF - Journal of strength and conditioning research : the research journal of the NSCA N2 - Previous studies contrasted the effects of plyometric training (PT) conducted on stable vs. unstable surfaces on components of physical fitness in child and adolescent soccer players. Depending on the training modality (stable vs. unstable), specific performance improvements were found for jump (stable PT) and balance performances (unstable PT). In an attempt to combine the effects of both training modalities, this study examined the effects of PT on stable surfaces compared with combined PT on stable and unstable surfaces on components of physical fitness in prepuberal male soccer athletes. Thirty-three boys were randomly assigned to either a PT on stable surfaces (PTS; n = 17; age = 12.1 +/- 0.5 years; height = 151.6 +/- 5.7 cm; body mass = 39.2 +/- 6.5 kg; and maturity offset = 22.3 +/- 0.5 years) or a combined PT on stable and unstable surfaces (PTC; n = 16; age = 12.2 +/- 0.6 years; height = 154.6 +/- 8.1 cm; body mass = 38.7 +/- 5.0 kg; and maturity offset = 22.2 +/- 0.6 years). Both intervention groups conducted 4 soccer-specific training sessions per week combined with either 2 PTS or PTC sessions. Before and after 8 weeks of training, proxies of muscle power (e.g., countermovement jump [CMJ], standing long jump [SLJ]), muscle strength (e.g., reactive strength index [RSI]), speed (e.g., 20-m sprint test), agility (e.g., modified Illinois change of direction test [MICODT]), static balance (e.g., stable stork bal-ance test [SSBT]), and dynamic balance (unstable stork balance test [USBT]) were tested. An analysis of covariance model was used to test between-group differences (PTS vs. PTC) at posttest using baseline outcomes as covariates. No significant between-group differences at posttest were observed for CMJ (p > 0.05, d = 0.41), SLJ (p > 0.05, d = 0.36), RSI (p > 0.05, d = 0.57), 20-m sprint test (p > 0.05, d = 0.06), MICODT (p > 0.05, d = 0.23), and SSBT (p > 0.05, d = 0.20). However, statistically significant between-group differences at posttest were noted for the USBT (p < 0.01, d = 1.49) in favor of the PTC group. For most physical fitness tests (except RSI), significant pre-to-post improvements were observed for both groups (p < 0.01, d = 0.55-3.96). Eight weeks of PTS or PTC resulted in similar performance improvements in components of physical fitness except for dynamic balance. From a performance-enhancing perspective, PTC is recommended for pediatric strength and conditioning coaches because it produced comparable training effects as PTS on proxies of muscle power, muscle strength, speed, agility, static balance, and additional effects on dynamic balance. KW - youth KW - football KW - stretch-shortening cycle KW - athletic performance KW - balance Y1 - 2017 SN - 1064-8011 SN - 1533-4287 VL - 31 SP - 3295 EP - 3304 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - JOUR A1 - Fühner, Thea Heidi A1 - Kliegl, Reinhold A1 - Arntz, Fabian A1 - Kriemler, Susi A1 - Granacher, Urs T1 - An update on secular trends in physical fitness of children and adolescents from 1972 to 2015 BT - a systematic review JF - Sports medicine N2 - Background There is evidence that physical fitness of children and adolescents (particularly cardiorespiratory endurance) has declined globally over the past decades. Ever since the first reports on negative trends in physical fitness, efforts have been undertaken by for instance the World Health Organization (WHO) to promote physical activity and fitness in children and adolescents. Therefore, it is timely to re-analyze the literature to examine whether previous reports on secular declines in physical fitness are still detectable or whether they need to be updated. Objectives The objective of this systematic review is to provide an 'update' on secular trends in selected components of physical fitness (i.e., cardiorespiratory endurance, relative muscle strength, proxies of muscle power, speed) in children and adolescents aged 6-18 years. Data Sources A systematic computerized literature search was conducted in the electronic databases PubMed and Web of Science to locate studies that explicitly reported secular trends in physical fitness of children and adolescents. Study Eligibility Criteria Studies were included in this systematic review if they examined secular trends between at least two time points across a minimum of 5 years. In addition, they had to document secular trends in any measure of cardiorespiratory endurance, relative muscle strength, proxies of muscle power or speed in apparently healthy children and adolescents aged 6-18 years. Study Appraisal and Synthesis Methods The included studies were coded for the following criteria: nation, physical fitness component (cardiorespiratory endurance, relative muscle strength, proxies of muscle power, speed), chronological age, sex (boys vs. girls), and year of assessment. Scores were standardized (i.e., converted to z scores) with sample-weighted means and standard deviations, pooled across sex and year of assessment within cells defined by study, test, and children's age. Results The original search identified 524 hits. In the end, 22 studies met the inclusion criteria for review. The observation period was between 1972 and 2015. Fifteen of the 22 studies used tests for cardiorespiratory endurance, eight for relative muscle strength, eleven for proxies of muscle power, and eight for speed. Measures of cardiorespiratory endurance exhibited a large initial increase and an equally large subsequent decrease, but the decrease appears to have reached a floor for all children between 2010 and 2015. Measures of relative muscle strength showed a general trend towards a small increase. Measures of proxies of muscle power indicated an overall small negative quadratic trend. For measures of speed, a small-to-medium increase was observed in recent years. Limitations Biological maturity was not considered in the analysis because biological maturity was not reported in most included studies. Conclusions Negative secular trends were particularly found for cardiorespiratory endurance between 1986 and 2010-12, irrespective of sex. Relative muscle strength and speed showed small increases while proxies of muscle power declined. Although the negative trend in cardiorespiratory endurance appears to have reached a floor in recent years, because of its association with markers of health, we recommend further initiatives in PA and fitness promotion for children and adolescents. More specifically, public health efforts should focus on exercise that increases cardiorespiratory endurance to prevent adverse health effects (i.e.
, overweight and obesity) and muscle strength to lay a foundation for motor skill learning. Y1 - 2020 U6 - https://doi.org/10.1007/s40279-020-01373-x SN - 0112-1642 SN - 1179-2035 VL - 51 IS - 2 SP - 303 EP - 320 PB - Springer CY - Northcote ER - TY - JOUR A1 - Teich, Paula A1 - Fühner, Thea Heidi A1 - Granacher, Urs A1 - Kliegl, Reinhold T1 - Physical fitness of primary school children differs depending on their timing of school enrollment JF - Scientific reports N2 - Previous research has shown that children who were enrolled to school according to the legal key date (i.e., keyage children, between eight and nine years in third grade) exhibited a linear physical fitness development in the ninth year of life. In contrast, children who were enrolled with a delay (i.e., older-than-keyage children [OTK], between nine and ten years in third grade) exhibited a lower physical fitness compared to what would be expected for their age. In these studies, cross-sectional age differences within third grade and timing of school enrollment were confounded. The present study investigated the longitudinal development of keyage and OTK children from third to fifth grade. This design also afforded a comparison of the two groups at the same average chronological age, that is a dissociation of the effects of timing of school enrollment and age. We tested six physical fitness components: cardiorespiratory endurance, coordination, speed, power of lower and upper limbs, and static balance. 1502 children (i.e., 1206 keyage and 296 OTK children) from 35 schools were tested in third, fourth, and fifth grade. Except for cardiorespiratory endurance, both groups developed from third to fourth and from fourth to fifth grade and keyage children outperformed OTK children at the average ages of 9.5 or 10.5 years. For cardiorespiratory endurance, there was no significant gain from fourth to fifth grade and keyage and OTK children did not differ significantly at 10.5 years of age. One reason for a delayed school enrollment could be that a child is (or is perceived as) biologically younger than their chronological age at the school entry examination, implying a negative correlation between chronological and biological age for OTK children. Indeed, a simple reflection of chronological age brought the developmental rate of the chronologically youngest OTK children in line with the developmental rate observed for keyage children, but did not eliminate all differences. The mapping of chronological and biological age of OTK children and other possible reasons for lower physical fitness of OTK children remain a task for future research. KW - Health care KW - Paediatrics KW - Physiology Y1 - 2023 U6 - https://doi.org/10.1038/s41598-023-35727-y SN - 2045-2322 VL - 13 IS - 1 PB - Springer Nature CY - London ER - TY - JOUR A1 - Fühner, Thea Heidi A1 - Granacher, Urs A1 - Golle, Kathleen A1 - Kliegl, Reinhold T1 - Effect of timing of school enrollment on physical fitness in third graders JF - Scientific Reports N2 - Timing of initial school enrollment may vary considerably for various reasons such as early or delayed enrollment, skipped or repeated school classes. Accordingly, the age range within school grades includes older-(OTK) and younger-than-keyage (YTK) children. Hardly any information is available on the impact of timing of school enrollment on physical fitness. There is evidence from a related research topic showing large differences in academic performance between OTK and YTK children versus keyage children. Thus, the aim of this study was to compare physical fitness of OTK (N = 26,540) and YTK (N = 2586) children versus keyage children (N = 108,295) in a representative sample of German third graders. Physical fitness tests comprised cardiorespiratory endurance, coordination, speed, lower, and upper limbs muscle power. Predictions of physical fitness performance for YTK and OTK children were estimated using data from keyage children by taking age, sex, school, and assessment year into account. Data were annually recorded between 2011 and 2019. The difference between observed and predicted z-scores yielded a delta z-score that was used as a dependent variable in the linear mixed models. Findings indicate that OTK children showed poorer performance compared to keyage children, especially in coordination, and that YTK children outperformed keyage children, especially in coordination. Teachers should be aware that OTK children show poorer physical fitness performance compared to keyage children. Y1 - 2022 U6 - https://doi.org/10.1038/s41598-022-11710-x SN - 2045-2322 VL - 12 SP - 1 EP - 11 PB - Springer Nature CY - London ER - TY - JOUR A1 - Fühner, Thea Heidi A1 - Granacher, Urs A1 - Golle, Kathleen A1 - Kliegl, Reinhold T1 - Age and sex effects in physical fitness components of 108,295 third graders including 515 primary schools and 9 cohorts JF - Scientific Reports N2 - Children’s physical fitness development and related moderating effects of age and sex are well documented, especially boys’ and girls’ divergence during puberty. The situation might be different during prepuberty. As girls mature approximately two years earlier than boys, we tested a possible convergence of performance with five tests representing four components of physical fitness in a large sample of 108,295 eight-year old third-graders. Within this single prepubertal year of life and irrespective of the test, performance increased linearly with chronological age, and boys outperformed girls to a larger extent in tests requiring muscle mass for successful performance. Tests differed in the magnitude of age effects (gains), but there was no evidence for an interaction between age and sex. Moreover, “physical fitness” of schools correlated at r = 0.48 with their age effect which might imply that "fit schools” promote larger gains; expected secular trends from 2011 to 2019 were replicated. Y1 - 2021 U6 - https://doi.org/10.1038/s41598-021-97000-4 SN - 2045-2322 VL - 11 SP - 1 EP - 13 PB - Nature Portfolio CY - Berlin ER - TY - JOUR A1 - Bohle, Hannah A1 - Rimpel, Jérôme A1 - Schauenburg, Gesche A1 - Gebel, Arnd A1 - Stelzel, Christine A1 - Heinzel, Stephan A1 - Rapp, Michael A. A1 - Granacher, Urs T1 - Behavioral and Neural Correlates of Cognitive-Motor Interference during Multitasking in Young and Old Adults JF - Neural Plasticity N2 - The concurrent performance of cognitive and postural tasks is particularly impaired in old adults and associated with an increased risk of falls. Biological aging of the cognitive and postural control system appears to be responsible for increased cognitive-motor interference effects. We examined neural and behavioral markers of motor-cognitive dual-task performance in young and old adults performing spatial one-back working memory single and dual tasks during semitandem stance. On the neural level, we used EEG to test for age-related modulations in the frequency domain related to cognitive-postural task load. Twenty-eight healthy young and 30 old adults participated in this study. The tasks included a postural single task, a cognitive-postural dual task, and a cognitive-postural triple task (cognitive dual-task with postural demands). Postural sway (i.e., total center of pressure displacements) was recorded in semistance position on an unstable surface that was placed on top of a force plate while performing cognitive tasks. Neural activation was recorded using a 64-channel mobile EEG system. EEG frequencies were attenuated by the baseline postural single-task condition and demarcated in nine Regions-of-Interest (ROIs), i.e., anterior, central, posterior, over the cortical midline, and both hemispheres. Our findings revealed impaired cognitive dual-task performance in old compared to young participants in the form of significantly lower cognitive performance in the triple-task condition. Furthermore, old adults compared with young adults showed significantly larger postural sway, especially in cognitive-postural task conditions. With respect to EEG frequencies, young compared to old participants showed significantly lower alpha-band activity in cognitive-cognitive-postural triple-task conditions compared with cognitive-postural dual tasks. In addition, with increasing task difficulty, we observed synchronized theta and delta frequencies, irrespective of age. Taskdependent alterations of the alpha frequency band were most pronounced over frontal and central ROIs, while alterations of the theta and delta frequency bands were found in frontal, central, and posterior ROIs. Theta and delta synchronization exhibited a decrease from anterior to posterior regions. For old adults, task difficulty was reflected by theta synchronization in the posterior ROI. For young adults, it was reflected by alpha desynchronization in bilateral anterior ROIs. In addition, we could not identify any effects of task difficulty and age on the beta frequency band. Our results shed light on age-related cognitive and postural declines and how they interact. Modulated alpha frequencies during high cognitive-postural task demands in young but not old adults might be reflective of a constrained neural adaptive potential in old adults. Future studies are needed to elucidate associations between the identified age-related performance decrements with task difficulty and changes in brain activity. Y1 - 2019 U6 - https://doi.org/10.1155/2019/9478656 SN - 2090-5904 SN - 1687-5443 PB - Hindawi CY - New York ER - TY - JOUR A1 - Stelzel, Christine A1 - Schauenburg, Gesche A1 - Rapp, Michael A. A1 - Heinzel, Stephan A1 - Granacher, Urs T1 - Age-Related Interference between the Selection of Input-Output Modality Mappings and Postural Control BT - a Pilot Study JF - Frontiers in psychology N2 - Age-related decline in executive functions and postural control due to degenerative processes in the central nervous system have been related to increased fall-risk in old age. Many studies have shown cognitive-postural dual-task interference in old adults, but research on the role of specific executive functions in this context has just begun. In this study, we addressed the question whether postural control is impaired depending on the coordination of concurrent response-selection processes related to the compatibility of input and output modality mappings as compared to impairments related to working-memory load in the comparison of cognitive dual and single tasks. Specifically, we measured total center of pressure (CoP) displacements in healthy female participants aged 19–30 and 66–84 years while they performed different versions of a spatial one-back working memory task during semi-tandem stance on an unstable surface (i.e., balance pad) while standing on a force plate. The specific working-memory tasks comprised: (i) modality compatible single tasks (i.e., visual-manual or auditory-vocal tasks), (ii) modality compatible dual tasks (i.e., visual-manual and auditory-vocal tasks), (iii) modality incompatible single tasks (i.e., visual-vocal or auditory-manual tasks), and (iv) modality incompatible dual tasks (i.e., visual-vocal and auditory-manual tasks). In addition, participants performed the same tasks while sitting. As expected from previous research, old adults showed generally impaired performance under high working-memory load (i.e., dual vs. single one-back task). In addition, modality compatibility affected one-back performance in dual-task but not in single-task conditions with strikingly pronounced impairments in old adults. Notably, the modality incompatible dual task also resulted in a selective increase in total CoP displacements compared to the modality compatible dual task in the old but not in the young participants. These results suggest that in addition to effects of working-memory load, processes related to simultaneously overcoming special linkages between input- and output modalities interfere with postural control in old but not in young female adults. Our preliminary data provide further evidence for the involvement of cognitive control processes in postural tasks. KW - cognitive-postural dual task KW - postural stability KW - working memory KW - modality compatibility KW - aging Y1 - 2017 U6 - https://doi.org/10.3389/fpsyg.2017.00613 SN - 1664-1078 VL - 8 PB - Frontiers Research Foundation CY - Lausanne ER -