TY - JOUR A1 - Abdalla, Hassan E. A1 - Abramowski, Attila A1 - Aharonian, Felix A. A1 - Benkhali, Faiçal Ait A1 - Akhperjanian, A. G. A1 - Angüner, Ekrem Oǧuzhan A1 - Arrieta, M. A1 - Aubert, Pierre A1 - Backes, Michael A1 - Balzer, Arnim A1 - Barnard, Michelle A1 - Becherini, Yvonne A1 - Tjus, Julia Becker A1 - Berge, David A1 - Bernhard, Sabrina A1 - Bernlöhr, K. A1 - Birsin, E. A1 - Blackwell, R. A1 - Bottcher, Markus A1 - Boisson, Catherine A1 - Bolmont, J. A1 - Bordas, Pol A1 - Bregeon, Johan A1 - Brun, Francois A1 - Brun, Pierre A1 - Bryan, Mark A1 - Bulik, Tomasz A1 - Capasso, M. A1 - Carr, John A1 - Casanova, Sabrina A1 - Chakraborty, N. A1 - Chalme-Calvet, R. A1 - Chaves, Ryan C. G. A1 - Chen, Andrew A1 - Chevalier, J. A1 - Chretien, M. A1 - Colafrancesco, Sergio A1 - Cologna, Gabriele A1 - Condon, B. A1 - Conrad, Jan A1 - Couturier, C. A1 - Cui, Y. A1 - Davids, I. D. A1 - Degrange, B. A1 - Deil, Christoph A1 - deWilt, P. A1 - Djannati-Atai, Arache A1 - Domainko, Wilfried A1 - Donath, Axel A1 - Dubus, Guillaume A1 - Dutson, Kate A1 - Dyks, J. A1 - Dyrda, M. A1 - Edwards, T. A1 - Egberts, Kathrin A1 - Eger, P. A1 - Ernenwein, J. -P. A1 - Eschbach, S. A1 - Farnier, C. A1 - Fegan, Stuart A1 - Fernandes, M. V. A1 - Fiasson, A. A1 - Fontaine, G. A1 - Foerster, A. A1 - Funk, S. A1 - Füßling, Matthias A1 - Gabici, Stefano A1 - Gajdus, M. A1 - Gallant, Y. A. A1 - Garrigoux, T. A1 - Giavitto, Gianluca A1 - Giebels, B. A1 - Glicenstein, J. F. A1 - Gottschall, Daniel A1 - Goyal, A. A1 - Grondin, M. -H. A1 - Grudzinska, M. A1 - Hadasch, Daniela A1 - Hahn, J. A1 - Hawkes, J. A1 - Heinzelmann, G. A1 - Henri, Gilles A1 - Hermann, G. A1 - Hervet, Olivier A1 - Hillert, A. A1 - Hinton, James Anthony A1 - Hofmann, Werner A1 - Hoischen, Clemens A1 - Holler, M. A1 - Horns, D. A1 - Ivascenko, Alex A1 - Jacholkowska, A. A1 - Jamrozy, Marek A1 - Janiak, M. A1 - Jankowsky, D. A1 - Jankowsky, Felix A1 - Jingo, M. A1 - Jogler, Tobias A1 - Jouvin, Lea A1 - Jung-Richardt, Ira A1 - Kastendieck, M. A. A1 - Katarzynski, Krzysztof A1 - Katz, Uli A1 - Kerszberg, D. A1 - Khelifi, B. A1 - Kieffer, M. A1 - King, J. A1 - Klepser, S. A1 - Klochkov, Dmitry A1 - Kluzniak, W. A1 - Kolitzus, D. A1 - Komin, Nu. A1 - Kosack, K. A1 - Krakau, S. A1 - Kraus, Michael A1 - Krayzel, F. A1 - Kruger, P. P. A1 - Laffon, H. A1 - Lamanna, G. A1 - Lau, Jeanie A1 - Lees, J. -P. A1 - Lefaucheur, J. A1 - Lefranc, V. A1 - Lemiere, A. A1 - Lemoine-Goumard, M. A1 - Lenain, J. -P. A1 - Leser, Eva A1 - Lohse, Thomas A1 - Lorentz, M. A1 - Lui, R. A1 - Lypova, Iryna A1 - Marandon, Vincent A1 - Marcowith, Alexandre A1 - Mariaud, C. A1 - Marx, R. A1 - Maurin, G. A1 - Maxted, N. A1 - Mayer, Michael A1 - Meintjes, Petrus Johannes A1 - Menzler, U. A1 - Meyer, Manuel A1 - Mitchell, A. M. W. A1 - Moderski, R. A1 - Mohamed, M. A1 - Mora, K. A1 - Moulin, Emmanuel A1 - Murach, T. A1 - de Naurois, Mathieu A1 - Niederwanger, F. A1 - Niemiec, J. A1 - Oakes, L. A1 - Odaka, Hirokazu A1 - Ohm, Stefan A1 - Oettl, S. A1 - Ostrowski, M. A1 - Oya, I. A1 - Padovani, Marco A1 - Panter, M. A1 - Parsons, R. D. A1 - Arribas, M. Paz A1 - Pekeur, N. W. A1 - Pelletier, G. A1 - Petrucci, P. -O. A1 - Peyaud, B. A1 - Pita, S. A1 - Poon, Helen A1 - Prokhorov, Dmitry A1 - Prokoph, Heike A1 - Puehlhofer, Gerd A1 - Punch, Michael A1 - Quirrenbach, Andreas A1 - Raab, S. A1 - Reimer, Anita A1 - Reimer, Olaf A1 - Renaud, M. A1 - de los Reyes, R. A1 - Rieger, Frank A1 - Romoli, Carlo A1 - Rosier-Lees, S. A1 - Rowell, G. A1 - Rudak, B. A1 - Rulten, C. B. A1 - Sahakian, V. A1 - Salek, David A1 - Sanchez, David A. A1 - Santangelo, Andrea A1 - Sasaki, Manami A1 - Schlickeiser, Reinhard A1 - Schussler, F. A1 - Schulz, Andreas A1 - Schwanke, U. A1 - Schwemmer, S. A1 - Seyffert, A. S. A1 - Shafi, N. A1 - Simoni, R. A1 - Sol, H. A1 - Spanier, Felix A1 - Spengler, G. A1 - Spiess, F. A1 - Stawarz, Lukasz A1 - Steenkamp, R. A1 - Stegmann, Christian A1 - Stinzing, F. A1 - Stycz, K. A1 - Sushch, Iurii A1 - Tavernet, J. -P. A1 - Tavernier, T. A1 - Taylor, A. M. A1 - Terrier, R. A1 - Tluczykont, Martin A1 - Trichard, C. A1 - Tuffs, R. A1 - van der Walt, Johan A1 - van Eldik, Christopher A1 - van Soelen, Brian A1 - Vasileiadis, Georges A1 - Veh, J. A1 - Venter, C. A1 - Viana, A. A1 - Vincent, P. A1 - Vink, Jacco A1 - Voisin, F. A1 - Voelk, Heinrich J. A1 - Vuillaume, Thomas A1 - Wadiasingh, Z. A1 - Wagner, Stefan J. A1 - Wagner, P. A1 - Wagner, R. M. A1 - White, R. A1 - Wierzcholska, Alicja A1 - Willmann, P. A1 - Woernlein, A. A1 - Wouters, Denis A1 - Yang, R. A1 - Zabalza, Victor A1 - Zaborov, D. A1 - Zacharias, M. A1 - Zdziarski, A. A. A1 - Zech, Andreas A1 - Zefi, F. A1 - Ziegler, A. A1 - Zywucka, Natalia T1 - Search for Dark Matter Annihilations towards the Inner Galactic Halo from 10 Years of Observations with HESS JF - Physical review letters N2 - The inner region of the Milky Way halo harbors a large amount of dark matter (DM). Given its proximity, it is one of the most promising targets to look for DM. We report on a search for the annihilations of DM particles using gamma-ray observations towards the inner 300 pc of the Milky Way, with the H.E.S.S. array of ground-based Cherenkov telescopes. The analysis is based on a 2D maximum likelihood method using Galactic Center (GC) data accumulated by H.E.S.S. over the last 10 years (2004-2014), and does not show any significant gamma-ray signal above background. Assuming Einasto and Navarro-Frenk-White DM density profiles at the GC, we derive upper limits on the annihilation cross section . These constraints are the strongest obtained so far in the TeV DM mass range and improve upon previous limits by a factor 5. For the Einasto profile, the constraints reach values of 6 x 10(-26) cm(3) s(-1) in the W+W- channel for a DM particle mass of 1.5 TeV, and 2 x 10(-26) cm(3) s(-1) in the tau(+)tau(-) channel for a 1 TeV mass. For the first time, ground-based gamma-ray observations have reached sufficient sensitivity to probe values expected from the thermal relic density for TeV DM particles. Y1 - 2016 U6 - https://doi.org/10.1103/PhysRevLett.117.111301 SN - 0031-9007 SN - 1079-7114 VL - 117 PB - American Physical Society CY - College Park ER - TY - GEN A1 - Abramowski, Attila A1 - Aharonian, Felix A. A1 - Benkhali, Faical Ait A1 - Akhperjanian, A. G. A1 - Angüner, Ekrem Oǧuzhan A1 - Backes, Michael A1 - Balenderan, Shangkari A1 - Balzer, Arnim A1 - Barnacka, Anna A1 - Becherini, Yvonne A1 - Tjus, Julia Becker A1 - Berge, David A1 - Bernhard, Sabrina A1 - Bernlöhr, Konrad A1 - Birsin, E. A1 - Biteau, Jonathan A1 - Böttcher, Markus A1 - Boisson, Catherine A1 - Bolmont, J. A1 - Bordas, Pol A1 - Bregeon, Johan A1 - Brun, Francois A1 - Brun, Pierre A1 - Bryan, Mark A1 - Bulik, Tomasz A1 - Carrigan, Svenja A1 - Casanova, Sabrina A1 - Chadwick, Paula M. A1 - Chakraborty, Nachiketa A1 - Chalme-Calvet, R. A1 - Chaves, Ryan C. G. A1 - Chretien, M. A1 - Colafrancesco, Sergio A1 - Cologna, Gabriele A1 - Conrad, Jan A1 - Couturier, Claire A1 - Cui, Yudong A1 - Davids, Isak Delberth A1 - Degrange, Bernhard A1 - Deil, Christoph A1 - deWilt, P. A1 - Djannati-Ataï, A. A1 - Domainko, Wilfried A1 - Donath, Axel A1 - Dubus, G. A1 - Dutson, K. A1 - Dyks, J. A1 - Dyrda, M. A1 - Edwards, Tanya A1 - Egberts, Kathrin A1 - Eger, Peter A1 - Espigat, P. A1 - Farnier, C. A1 - Fegan, Stephen A1 - Feinstein, Fabrice A1 - Fernandes, Milton Virgilio A1 - Fernandez, Diane A1 - Fiasson, A. A1 - Fontaine, Gerard A1 - Förster, Andreas A1 - Fuessling, M. A1 - Gabici, S. A1 - Gajdus, M. A1 - Gallant, Yves A. A1 - Garrigoux, Tania A1 - Giavitto, G. A1 - Giebels, Berrie A1 - Glicenstein, Jean-Francois A1 - Gottschall, Daniel A1 - Grondin, M. -H. A1 - Grudzinska, M. A1 - Hadasch, Daniela A1 - Haeffner, S. A1 - Hahn, Joachim A1 - Harris, Jonathan A1 - Heinzelmann, Götz A1 - Henri, G. A1 - Hermann, German A1 - Hervet, O. A1 - Hillert, Andreas A1 - Hinton, James Anthony A1 - Hofmann, Werner A1 - Hofverberg, Petter A1 - Holler, Markus A1 - Horns, Dieter A1 - Ivascenko, Alex A1 - Jacholkowska, A. A1 - Jahn, C. A1 - Jamrozy, Marek A1 - Janiak, M. A1 - Jankowsky, F. A1 - Jung-Richardt, I. A1 - Kastendieck, Max Anton A1 - Katarzynski, K. A1 - Katz, U. A1 - Kaufmann, S. A1 - Khelifi, B. A1 - Kieffer, Michel A1 - Klepser, S. A1 - Klochkov, Dmitry A1 - Kluzniak, W. A1 - Kolitzus, David A1 - Komin, Nu A1 - Kosack, Karl A1 - Krakau, Steffen A1 - Krayzel, F. A1 - Krueger, Pat P. A1 - Laffon, H. A1 - Lamanna, G. A1 - Lefaucheur, J. A1 - Lefranc, Valentin A1 - Lemiere, A. A1 - Lemoine-Goumard, M. A1 - Lenain, J. -P. A1 - Lohse, Thomas A1 - Lopatin, A. A1 - Lu, Chia-Chun A1 - Marandon, Vincent A1 - Marcowith, Alexandre A1 - Marx, Ramin A1 - Maurin, G. A1 - Maxted, Nigel A1 - Mayer, Michael A1 - McComb, T. J. Lowry A1 - Mehault, J. A1 - Meintjes, P. J. A1 - Menzler, Ulf A1 - Meyer, M. A1 - Mitchell, Alison M. W. A1 - Moderski, R. A1 - Mohamed, M. A1 - Mora, K. A1 - Moulin, Emmanuel A1 - Murach, Thomas A1 - de Naurois, Mathieu A1 - Niemiec, J. A1 - Nolan, Sam J. A1 - Oakes, Louise A1 - Odaka, Hirokazu A1 - Ohm, S. A1 - Optiz, Björn A1 - Ostrowski, Michal A1 - Oya, I. A1 - Panter, Michael A1 - Parsons, R. Daniel A1 - Arribas, M. Paz A1 - Pekeur, Nikki W. A1 - Pelletier, G. A1 - Petrucci, P. -O. A1 - Peyaud, B. A1 - Pita, S. A1 - Poon, Helen A1 - Pühlhofer, Gerd A1 - Punch, M. A1 - Quirrenbach, A. A1 - Raab, S. A1 - Reichardt, I. A1 - Reimer, Anita A1 - Reimer, Olaf A1 - Renaud, Metz A1 - de los Reyes, Raquel A1 - Rieger, Frank A1 - Romoli, C. A1 - Rosier-Lees, S. A1 - Rowell, G. A1 - Rudak, B. A1 - Rulten, C. B. A1 - Sahakian, Vardan A1 - Salek, D. A1 - Sanchez, David M. A1 - Santangelo, Andrea A1 - Schlickeiser, Reinhard A1 - Schuessler, F. A1 - Schulz, A. A1 - Schwanke, Ullrich A1 - Schwarzburg, S. A1 - Schwemmer, S. A1 - Sol, H. A1 - Spanier, Felix A1 - Spengler, G. A1 - Spies, Franziska A1 - Stawarz, Lukasz A1 - Steenkamp, Riaan A1 - Stegmann, Christian A1 - Stinzing, F. A1 - Stycz, K. A1 - Sushch, Iurii A1 - Tavernet, J. -P. A1 - Tavernier, T. A1 - Taylor, A. M. A1 - Terrier, R. A1 - Tluczykont, Martin A1 - Trichard, C. A1 - Valerius, K. A1 - van Eldik, C. A1 - van Soelen, B. A1 - Vasileiadis, Georges A1 - Veh, J. A1 - Venter, Christo A1 - Viana, Aion A1 - Vincent, P. A1 - Vink, Jacco A1 - Völk, Heinrich J. A1 - Volpe, Francesca A1 - Vorster, Martine A1 - Vuillaume, T. A1 - Wagner, S. J. A1 - Wagner, P. A1 - Wagner, R. M. A1 - Ward, Martin A1 - Weidinger, Matthias A1 - Weitzel, Quirin A1 - White, R. A1 - Wierzcholska, A. A1 - Willmann, P. A1 - Woernlein, A. A1 - Wouters, D. A1 - Yang, Ruizhi A1 - Zabalza, Victor A1 - Zaborov, Dmitry A1 - Zacharias, M. A1 - Zdziarski, A. A. A1 - Zech, Alraune A1 - Zechlin, Hannes -S. T1 - H.E.S.S. detection of TeV emission from the interaction region between the supernova remnant G349.7+0.2 and a molecular cloud (vol 574, A100, 2015) T2 - Astronomy and astrophysics : an international weekly journal KW - gamma rays: general KW - ISM: supernova remnants KW - ISM: clouds KW - errata, addenda Y1 - 2015 U6 - https://doi.org/10.1051/0004-6361/201425070e SN - 1432-0746 VL - 580 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - Aarts, Alexander A. A1 - Anderson, Joanna E. A1 - Anderson, Christopher J. A1 - Attridge, Peter R. A1 - Attwood, Angela A1 - Axt, Jordan A1 - Babel, Molly A1 - Bahnik, Stepan A1 - Baranski, Erica A1 - Barnett-Cowan, Michael A1 - Bartmess, Elizabeth A1 - Beer, Jennifer A1 - Bell, Raoul A1 - Bentley, Heather A1 - Beyan, Leah A1 - Binion, Grace A1 - Borsboom, Denny A1 - Bosch, Annick A1 - Bosco, Frank A. A1 - Bowman, Sara D. A1 - Brandt, Mark J. A1 - Braswell, Erin A1 - Brohmer, Hilmar A1 - Brown, Benjamin T. A1 - Brown, Kristina A1 - Bruening, Jovita A1 - Calhoun-Sauls, Ann A1 - Callahan, Shannon P. A1 - Chagnon, Elizabeth A1 - Chandler, Jesse A1 - Chartier, Christopher R. A1 - Cheung, Felix A1 - Christopherson, Cody D. A1 - Cillessen, Linda A1 - Clay, Russ A1 - Cleary, Hayley A1 - Cloud, Mark D. A1 - Cohn, Michael A1 - Cohoon, Johanna A1 - Columbus, Simon A1 - Cordes, Andreas A1 - Costantini, Giulio A1 - Alvarez, Leslie D. Cramblet A1 - Cremata, Ed A1 - Crusius, Jan A1 - DeCoster, Jamie A1 - DeGaetano, Michelle A. A1 - Della Penna, Nicolas A1 - den Bezemer, Bobby A1 - Deserno, Marie K. A1 - Devitt, Olivia A1 - Dewitte, Laura A1 - Dobolyi, David G. A1 - Dodson, Geneva T. A1 - Donnellan, M. Brent A1 - Donohue, Ryan A1 - Dore, Rebecca A. A1 - Dorrough, Angela A1 - Dreber, Anna A1 - Dugas, Michelle A1 - Dunn, Elizabeth W. A1 - Easey, Kayleigh A1 - Eboigbe, Sylvia A1 - Eggleston, Casey A1 - Embley, Jo A1 - Epskamp, Sacha A1 - Errington, Timothy M. A1 - Estel, Vivien A1 - Farach, Frank J. A1 - Feather, Jenelle A1 - Fedor, Anna A1 - Fernandez-Castilla, Belen A1 - Fiedler, Susann A1 - Field, James G. A1 - Fitneva, Stanka A. A1 - Flagan, Taru A1 - Forest, Amanda L. A1 - Forsell, Eskil A1 - Foster, Joshua D. A1 - Frank, Michael C. A1 - Frazier, Rebecca S. A1 - Fuchs, Heather A1 - Gable, Philip A1 - Galak, Jeff A1 - Galliani, Elisa Maria A1 - Gampa, Anup A1 - Garcia, Sara A1 - Gazarian, Douglas A1 - Gilbert, Elizabeth A1 - Giner-Sorolla, Roger A1 - Glöckner, Andreas A1 - Göllner, Lars A1 - Goh, Jin X. A1 - Goldberg, Rebecca A1 - Goodbourn, Patrick T. A1 - Gordon-McKeon, Shauna A1 - Gorges, Bryan A1 - Gorges, Jessie A1 - Goss, Justin A1 - Graham, Jesse A1 - Grange, James A. A1 - Gray, Jeremy A1 - Hartgerink, Chris A1 - Hartshorne, Joshua A1 - Hasselman, Fred A1 - Hayes, Timothy A1 - Heikensten, Emma A1 - Henninger, Felix A1 - Hodsoll, John A1 - Holubar, Taylor A1 - Hoogendoorn, Gea A1 - Humphries, Denise J. A1 - Hung, Cathy O. -Y. A1 - Immelman, Nathali A1 - Irsik, Vanessa C. A1 - Jahn, Georg A1 - Jaekel, Frank A1 - Jekel, Marc A1 - Johannesson, Magnus A1 - Johnson, Larissa G. A1 - Johnson, David J. A1 - Johnson, Kate M. A1 - Johnston, William J. A1 - Jonas, Kai A1 - Joy-Gaba, Jennifer A. A1 - Kappes, Heather Barry A1 - Kelso, Kim A1 - Kidwell, Mallory C. A1 - Kim, Seung Kyung A1 - Kirkhart, Matthew A1 - Kleinberg, Bennett A1 - Knezevic, Goran A1 - Kolorz, Franziska Maria A1 - Kossakowski, Jolanda J. A1 - Krause, Robert Wilhelm A1 - Krijnen, Job A1 - Kuhlmann, Tim A1 - Kunkels, Yoram K. A1 - Kyc, Megan M. A1 - Lai, Calvin K. A1 - Laique, Aamir A1 - Lakens, Daniel A1 - Lane, Kristin A. A1 - Lassetter, Bethany A1 - Lazarevic, Ljiljana B. A1 - LeBel, Etienne P. A1 - Lee, Key Jung A1 - Lee, Minha A1 - Lemm, Kristi A1 - Levitan, Carmel A. A1 - Lewis, Melissa A1 - Lin, Lin A1 - Lin, Stephanie A1 - Lippold, Matthias A1 - Loureiro, Darren A1 - Luteijn, Ilse A1 - Mackinnon, Sean A1 - Mainard, Heather N. A1 - Marigold, Denise C. A1 - Martin, Daniel P. A1 - Martinez, Tylar A1 - Masicampo, E. J. A1 - Matacotta, Josh A1 - Mathur, Maya A1 - May, Michael A1 - Mechin, Nicole A1 - Mehta, Pranjal A1 - Meixner, Johannes A1 - Melinger, Alissa A1 - Miller, Jeremy K. A1 - Miller, Mallorie A1 - Moore, Katherine A1 - Möschl, Marcus A1 - Motyl, Matt A1 - Müller, Stephanie M. A1 - Munafo, Marcus A1 - Neijenhuijs, Koen I. A1 - Nervi, Taylor A1 - Nicolas, Gandalf A1 - Nilsonne, Gustav A1 - Nosek, Brian A. A1 - Nuijten, Michele B. A1 - Olsson, Catherine A1 - Osborne, Colleen A1 - Ostkamp, Lutz A1 - Pavel, Misha A1 - Penton-Voak, Ian S. A1 - Perna, Olivia A1 - Pernet, Cyril A1 - Perugini, Marco A1 - Pipitone, R. Nathan A1 - Pitts, Michael A1 - Plessow, Franziska A1 - Prenoveau, Jason M. A1 - Rahal, Rima-Maria A1 - Ratliff, Kate A. A1 - Reinhard, David A1 - Renkewitz, Frank A1 - Ricker, Ashley A. A1 - Rigney, Anastasia A1 - Rivers, Andrew M. A1 - Roebke, Mark A1 - Rutchick, Abraham M. A1 - Ryan, Robert S. A1 - Sahin, Onur A1 - Saide, Anondah A1 - Sandstrom, Gillian M. A1 - Santos, David A1 - Saxe, Rebecca A1 - Schlegelmilch, Rene A1 - Schmidt, Kathleen A1 - Scholz, Sabine A1 - Seibel, Larissa A1 - Selterman, Dylan Faulkner A1 - Shaki, Samuel A1 - Simpson, William B. A1 - Sinclair, H. Colleen A1 - Skorinko, Jeanine L. M. A1 - Slowik, Agnieszka A1 - Snyder, Joel S. A1 - Soderberg, Courtney A1 - Sonnleitner, Carina A1 - Spencer, Nick A1 - Spies, Jeffrey R. A1 - Steegen, Sara A1 - Stieger, Stefan A1 - Strohminger, Nina A1 - Sullivan, Gavin B. A1 - Talhelm, Thomas A1 - Tapia, Megan A1 - te Dorsthorst, Anniek A1 - Thomae, Manuela A1 - Thomas, Sarah L. A1 - Tio, Pia A1 - Traets, Frits A1 - Tsang, Steve A1 - Tuerlinckx, Francis A1 - Turchan, Paul A1 - Valasek, Milan A1 - Van Aert, Robbie A1 - van Assen, Marcel A1 - van Bork, Riet A1 - van de Ven, Mathijs A1 - van den Bergh, Don A1 - van der Hulst, Marije A1 - van Dooren, Roel A1 - van Doorn, Johnny A1 - van Renswoude, Daan R. A1 - van Rijn, Hedderik A1 - Vanpaemel, Wolf A1 - Echeverria, Alejandro Vasquez A1 - Vazquez, Melissa A1 - Velez, Natalia A1 - Vermue, Marieke A1 - Verschoor, Mark A1 - Vianello, Michelangelo A1 - Voracek, Martin A1 - Vuu, Gina A1 - Wagenmakers, Eric-Jan A1 - Weerdmeester, Joanneke A1 - Welsh, Ashlee A1 - Westgate, Erin C. A1 - Wissink, Joeri A1 - Wood, Michael A1 - Woods, Andy A1 - Wright, Emily A1 - Wu, Sining A1 - Zeelenberg, Marcel A1 - Zuni, Kellylynn T1 - Estimating the reproducibility of psychological science JF - Science N2 - Reproducibility is a defining feature of science, but the extent to which it characterizes current research is unknown. We conducted replications of 100 experimental and correlational studies published in three psychology journals using high-powered designs and original materials when available. Replication effects were half the magnitude of original effects, representing a substantial decline. Ninety-seven percent of original studies had statistically significant results. Thirty-six percent of replications had statistically significant results; 47% of original effect sizes were in the 95% confidence interval of the replication effect size; 39% of effects were subjectively rated to have replicated the original result; and if no bias in original results is assumed, combining original and replication results left 68% with statistically significant effects. Correlational tests suggest that replication success was better predicted by the strength of original evidence than by characteristics of the original and replication teams. Y1 - 2015 U6 - https://doi.org/10.1126/science.aac4716 SN - 1095-9203 SN - 0036-8075 VL - 349 IS - 6251 PB - American Assoc. for the Advancement of Science CY - Washington ER - TY - JOUR A1 - Taal, H. Rob A1 - St Pourcain, Beate A1 - Thiering, Elisabeth A1 - Das, Shikta A1 - Mook-Kanamori, Dennis O. A1 - Warrington, Nicole M. A1 - Kaakinen, Marika A1 - Kreiner-Moller, Eskil A1 - Bradfield, Jonathan P. A1 - Freathy, Rachel M. A1 - Geller, Frank A1 - Guxens, Monica A1 - Cousminer, Diana L. A1 - Kerkhof, Marjan A1 - Timpson, Nicholas J. A1 - Ikram, M. Arfan A1 - Beilin, Lawrence J. A1 - Bonnelykke, Klaus A1 - Buxton, Jessica L. A1 - Charoen, Pimphen A1 - Chawes, Bo Lund Krogsgaard A1 - Eriksson, Johan A1 - Evans, David M. A1 - Hofman, Albert A1 - Kemp, John P. A1 - Kim, Cecilia E. A1 - Klopp, Norman A1 - Lahti, Jari A1 - Lye, Stephen J. A1 - McMahon, George A1 - Mentch, Frank D. A1 - Mueller-Nurasyid, Martina A1 - O'Reilly, Paul F. A1 - Prokopenko, Inga A1 - Rivadeneira, Fernando A1 - Steegers, Eric A. P. A1 - Sunyer, Jordi A1 - Tiesler, Carla A1 - Yaghootkar, Hanieh A1 - Breteler, Monique M. B. A1 - Debette, Stephanie A1 - Fornage, Myriam A1 - Gudnason, Vilmundur A1 - Launer, Lenore J. A1 - van der Lugt, Aad A1 - Mosley, Thomas H. A1 - Seshadri, Sudha A1 - Smith, Albert V. A1 - Vernooij, Meike W. A1 - Blakemore, Alexandra I. F. A1 - Chiavacci, Rosetta M. A1 - Feenstra, Bjarke A1 - Fernandez-Banet, Julio A1 - Grant, Struan F. A. A1 - Hartikainen, Anna-Liisa A1 - van der Heijden, Albert J. A1 - Iniguez, Carmen A1 - Lathrop, Mark A1 - McArdle, Wendy L. A1 - Molgaard, Anne A1 - Newnham, John P. A1 - Palmer, Lyle J. A1 - Palotie, Aarno A1 - Pouta, Annneli A1 - Ring, Susan M. A1 - Sovio, Ulla A1 - Standl, Marie A1 - Uitterlinden, Andre G. A1 - Wichmann, H-Erich A1 - Vissing, Nadja Hawwa A1 - DeCarli, Charles A1 - van Duijn, Cornelia M. A1 - McCarthy, Mark I. A1 - Koppelman, Gerard H. A1 - Estivill, Xavier A1 - Hattersley, Andrew T. A1 - Melbye, Mads A1 - Bisgaard, Hans A1 - Pennell, Craig E. A1 - Widen, Elisabeth A1 - Hakonarson, Hakon A1 - Smith, George Davey A1 - Heinrich, Joachim A1 - Jarvelin, Marjo-Riitta A1 - Jaddoe, Vincent W. V. A1 - Adair, Linda S. A1 - Ang, Wei A1 - Atalay, Mustafa A1 - van Beijsterveldt, Toos A1 - Bergen, Nienke A1 - Benke, Kelly A1 - Berry, Diane J. A1 - Bradfield, Jonathan P. A1 - Charoen, Pimphen A1 - Coin, Lachlan A1 - Cousminer, Diana L. A1 - Das, Shikta A1 - Davis, Oliver S. P. A1 - Elliott, Paul A1 - Evans, David M. A1 - Feenstra, Bjarke A1 - Flexeder, Claudia A1 - Frayling, Tim A1 - Freathy, Rachel M. A1 - Gaillard, Romy A1 - Geller, Frank A1 - Groen-Blokhuis, Maria A1 - Goh, Liang-Kee A1 - Guxens, Monica A1 - Haworth, Claire M. A. A1 - Hadley, Dexter A1 - Hebebrand, Johannes A1 - Hinney, Anke A1 - Hirschhorn, Joel N. A1 - Holloway, John W. A1 - Holst, Claus A1 - Hottenga, Jouke Jan A1 - Horikoshi, Momoko A1 - Huikari, Ville A1 - Hypponen, Elina A1 - Iniguez, Carmen A1 - Kaakinen, Marika A1 - Kilpelainen, Tuomas O. A1 - Kirin, Mirna A1 - Kowgier, Matthew A1 - Lakka, Hanna-Maaria A1 - Lange, Leslie A. A1 - Lawlor, Debbie A. A1 - Lehtimaki, Terho A1 - Lewin, Alex A1 - Lindgren, Cecilia A1 - Lindi, Virpi A1 - Maggi, Reedik A1 - Marsh, Julie A1 - Middeldorp, Christel A1 - Millwood, Iona A1 - Mook-Kanamori, Dennis O. A1 - Murray, Jeffrey C. A1 - Nivard, Michel A1 - Nohr, Ellen Aagaard A1 - Ntalla, Ioanna A1 - Oken, Emily A1 - O'Reilly, Paul F. A1 - Palmer, Lyle J. A1 - Panoutsopoulou, Kalliope A1 - Pararajasingham, Jennifer A1 - Prokopenko, Inga A1 - Rodriguez, Alina A1 - Salem, Rany M. A1 - Sebert, Sylvain A1 - Siitonen, Niina A1 - Sovio, Ulla A1 - St Pourcain, Beate A1 - Strachan, David P. A1 - Sunyer, Jordi A1 - Taal, H. Rob A1 - Teo, Yik-Ying A1 - Thiering, Elisabeth A1 - Tiesler, Carla A1 - Uitterlinden, Andre G. A1 - Valcarcel, Beatriz A1 - Warrington, Nicole M. A1 - White, Scott A1 - Willemsen, Gonneke A1 - Yaghootkar, Hanieh A1 - Zeggini, Eleftheria A1 - Boomsma, Dorret I. A1 - Cooper, Cyrus A1 - Estivill, Xavier A1 - Gillman, Matthew A1 - Grant, Struan F. A. A1 - Hakonarson, Hakon A1 - Hattersley, Andrew T. A1 - Heinrich, Joachim A1 - Hocher, Berthold A1 - Jaddoe, Vincent W. V. A1 - Jarvelin, Marjo-Riitta A1 - Lakka, Timo A. A1 - McCarthy, Mark I. A1 - Melbye, Mads A1 - Mohlke, Karen L. A1 - Dedoussis, George V. A1 - Ong, Ken K. A1 - Pearson, Ewan R. A1 - Pennell, Craig E. A1 - Price, Thomas S. A1 - Power, Chris A1 - Raitakari, Olli T. A1 - Saw, Seang-Mei A1 - Scherag, Andre A1 - Simell, Olli A1 - Sorensen, Thorkild I. A. A1 - Timpson, Nicholas J. A1 - Widen, Elisabeth A1 - Wilson, James F. A1 - Ang, Wei A1 - van Beijsterveldt, Toos A1 - Bergen, Nienke A1 - Benke, Kelly A1 - Berry, Diane J. A1 - Bradfield, Jonathan P. A1 - Charoen, Pimphen A1 - Coin, Lachlan A1 - Cousminer, Diana L. A1 - Das, Shikta A1 - Elliott, Paul A1 - Evans, David M. A1 - Frayling, Tim A1 - Freathy, Rachel M. A1 - Gaillard, Romy A1 - Groen-Blokhuis, Maria A1 - Guxens, Monica A1 - Hadley, Dexter A1 - Hottenga, Jouke Jan A1 - Huikari, Ville A1 - Hypponen, Elina A1 - Kaakinen, Marika A1 - Kowgier, Matthew A1 - Lawlor, Debbie A. A1 - Lewin, Alex A1 - Lindgren, Cecilia A1 - Marsh, Julie A1 - Middeldorp, Christel A1 - Millwood, Iona A1 - Mook-Kanamori, Dennis O. A1 - Nivard, Michel A1 - O'Reilly, Paul F. A1 - Palmer, Lyle J. A1 - Prokopenko, Inga A1 - Rodriguez, Alina A1 - Sebert, Sylvain A1 - Sovio, Ulla A1 - St Pourcain, Beate A1 - Standl, Marie A1 - Strachan, David P. A1 - Sunyer, Jordi A1 - Taal, H. Rob A1 - Thiering, Elisabeth A1 - Tiesler, Carla A1 - Uitterlinden, Andre G. A1 - Valcarcel, Beatriz A1 - Warrington, Nicole M. A1 - White, Scott A1 - Willemsen, Gonneke A1 - Yaghootkar, Hanieh A1 - Boomsma, Dorret I. A1 - Estivill, Xavier A1 - Grant, Struan F. A. A1 - Hakonarson, Hakon A1 - Hattersley, Andrew T. A1 - Heinrich, Joachim A1 - Jaddoe, Vincent W. V. A1 - Jarvelin, Marjo-Riitta A1 - McCarthy, Mark I. A1 - Pennell, Craig E. A1 - Power, Chris A1 - Timpson, Nicholas J. A1 - Widen, Elisabeth A1 - Ikram, M. Arfan A1 - Fornage, Myriam A1 - Smith, Albert V. A1 - Seshadri, Sudha A1 - Schmidt, Reinhold A1 - Debette, Stephanie A1 - Vrooman, Henri A. A1 - Sigurdsson, Sigurdur A1 - Ropele, Stefan A1 - Coker, Laura H. A1 - Longstreth, W. T. A1 - Niessen, Wiro J. A1 - DeStefano, Anita L. A1 - Beiser, Alexa A1 - Zijdenbos, Alex P. A1 - Struchalin, Maksim A1 - Jack, Clifford R. A1 - Nalls, Mike A. A1 - Au, Rhoda A1 - Hofman, Albert A1 - Gudnason, Haukur A1 - van der Lugt, Aad A1 - Harris, Tamara B. A1 - Meeks, William M. A1 - Vernooij, Meike W. A1 - van Buchem, Mark A. A1 - Catellier, Diane A1 - Gudnason, Vilmundur A1 - Windham, B. Gwen A1 - Wolf, Philip A. A1 - van Duijn, Cornelia M. A1 - Mosley, Thomas H. A1 - Schmidt, Helena A1 - Launer, Lenore J. A1 - Breteler, Monique M. B. A1 - DeCarli, Charles T1 - Common variants at 12q15 and 12q24 are associated with infant head circumference JF - Nature genetics N2 - To identify genetic variants associated with head circumference in infancy, we performed a meta-analysis of seven genome-wide association studies (GWAS) (N = 10,768 individuals of European ancestry enrolled in pregnancy and/or birth cohorts) and followed up three lead signals in six replication studies (combined N = 19,089). rs7980687 on chromosome 12q24 (P = 8.1 x 10(-9)) and rs1042725 on chromosome 12q15 (P = 2.8 x 10(-10)) were robustly associated with head circumference in infancy. Although these loci have previously been associated with adult height(1), their effects on infant head circumference were largely independent of height (P = 3.8 x 10(-7) for rs7980687 and P = 1.3 x 10(-7) for rs1042725 after adjustment for infant height). A third signal, rs11655470 on chromosome 17q21, showed suggestive evidence of association with head circumference (P = 3.9 x 10(-6)). SNPs correlated to the 17q21 signal have shown genome-wide association with adult intracranial volume(2), Parkinson's disease and other neurodegenerative diseases(3-5), indicating that a common genetic variant in this region might link early brain growth with neurological disease in later life. Y1 - 2012 U6 - https://doi.org/10.1038/ng.2238 SN - 1061-4036 VL - 44 IS - 5 SP - 532 EP - + PB - Nature Publ. Group CY - New York ER - TY - JOUR A1 - Thomas, Jessica E. A1 - Carvalho, Gary R. A1 - Haile, James A1 - Rawlence, Nicolas J. A1 - Martin, Michael D. A1 - Ho, Simon Y. W. A1 - Sigfusson, Arnor P. A1 - Josefsson, Vigfus A. A1 - Frederiksen, Morten A1 - Linnebjerg, Jannie F. A1 - Castruita, Jose A. Samaniego A1 - Niemann, Jonas A1 - Sinding, Mikkel-Holger S. A1 - Sandoval-Velasco, Marcela A1 - Soares, Andre E. R. A1 - Lacy, Robert A1 - Barilaro, Christina A1 - Best, Juila A1 - Brandis, Dirk A1 - Cavallo, Chiara A1 - Elorza, Mikelo A1 - Garrett, Kimball L. A1 - Groot, Maaike A1 - Johansson, Friederike A1 - Lifjeld, Jan T. A1 - Nilson, Goran A1 - Serjeanston, Dale A1 - Sweet, Paul A1 - Fuller, Errol A1 - Hufthammer, Anne Karin A1 - Meldgaard, Morten A1 - Fjeldsa, Jon A1 - Shapiro, Beth A1 - Hofreiter, Michael A1 - Stewart, John R. A1 - Gilbert, M. Thomas P. A1 - Knapp, Michael T1 - Demographic reconstruction from ancient DNA supports rapid extinction of the great auk JF - eLife N2 - The great auk was once abundant and distributed across the North Atlantic. It is now extinct, having been heavily exploited for its eggs, meat, and feathers. We investigated the impact of human hunting on its demise by integrating genetic data, GPS-based ocean current data, and analyses of population viability. We sequenced complete mitochondrial genomes of 41 individuals from across the species' geographic range and reconstructed population structure and population dynamics throughout the Holocene. Taken together, our data do not provide any evidence that great auks were at risk of extinction prior to the onset of intensive human hunting in the early 16th century. In addition, our population viability analyses reveal that even if the great auk had not been under threat by environmental change, human hunting alone could have been sufficient to cause its extinction. Our results emphasise the vulnerability of even abundant and widespread species to intense and localised exploitation. Y1 - 2019 U6 - https://doi.org/10.7554/eLife.47509 SN - 2050-084X VL - 8 PB - eLife Sciences Publications CY - Cambridge ER - TY - JOUR A1 - Hofman, Maarten P. G. A1 - Hayward, M. W. A1 - Heim, M. A1 - Marchand, P. A1 - Rolandsen, C. M. A1 - Mattisson, Jenny A1 - Urbano, F. A1 - Heurich, M. A1 - Mysterud, A. A1 - Melzheimer, J. A1 - Morellet, N. A1 - Voigt, Ulrich A1 - Allen, B. L. A1 - Gehr, Benedikt A1 - Rouco Zufiaurre, Carlos A1 - Ullmann, Wiebke A1 - Holand, O. A1 - Jorgensen, n H. A1 - Steinheim, G. A1 - Cagnacci, F. A1 - Kroeschel, M. A1 - Kaczensky, P. A1 - Buuveibaatar, B. A1 - Payne, J. C. A1 - Palmegiani, I A1 - Jerina, K. A1 - Kjellander, P. A1 - Johansson, O. A1 - LaPoint, S. A1 - Bayrakcismith, R. A1 - Linnell, J. D. C. A1 - Zaccaroni, M. A1 - Jorge, M. L. S. A1 - Oshima, J. E. F. A1 - Songhurst, A. A1 - Fischer, C. A1 - Mc Bride, R. T. A1 - Thompson, J. J. A1 - Streif, S. A1 - Sandfort, R. A1 - Bonenfant, Christophe A1 - Drouilly, M. A1 - Klapproth, M. A1 - Zinner, Dietmar A1 - Yarnell, Richard A1 - Stronza, A. A1 - Wilmott, L. A1 - Meisingset, E. A1 - Thaker, Maria A1 - Vanak, A. T. A1 - Nicoloso, S. A1 - Graeber, R. A1 - Said, S. A1 - Boudreau, M. R. A1 - Devlin, A. A1 - Hoogesteijn, R. A1 - May-Junior, J. A. A1 - Nifong, J. C. A1 - Odden, J. A1 - Quigley, H. B. A1 - Tortato, F. A1 - Parker, D. M. A1 - Caso, A. A1 - Perrine, J. A1 - Tellaeche, C. A1 - Zieba, F. A1 - Zwijacz-Kozica, T. A1 - Appel, C. L. A1 - Axsom, I A1 - Bean, W. T. A1 - Cristescu, B. A1 - Periquet, S. A1 - Teichman, K. J. A1 - Karpanty, S. A1 - Licoppe, A. A1 - Menges, V A1 - Black, K. A1 - Scheppers, Thomas L. A1 - Schai-Braun, S. C. A1 - Azevedo, F. C. A1 - Lemos, F. G. A1 - Payne, A. A1 - Swanepoel, L. H. A1 - Weckworth, B. A1 - Berger, A. A1 - Bertassoni, Alessandra A1 - McCulloch, G. A1 - Sustr, P. A1 - Athreya, V A1 - Bockmuhl, D. A1 - Casaer, J. A1 - Ekori, A. A1 - Melovski, D. A1 - Richard-Hansen, C. A1 - van de Vyver, D. A1 - Reyna-Hurtado, R. A1 - Robardet, E. A1 - Selva, N. A1 - Sergiel, A. A1 - Farhadinia, M. S. A1 - Sunde, P. A1 - Portas, R. A1 - Ambarli, Hüseyin A1 - Berzins, R. A1 - Kappeler, P. M. A1 - Mann, G. K. A1 - Pyritz, L. A1 - Bissett, C. A1 - Grant, T. A1 - Steinmetz, R. A1 - Swedell, Larissa A1 - Welch, R. J. A1 - Armenteras, D. A1 - Bidder, O. R. A1 - Gonzalez, T. M. A1 - Rosenblatt, A. A1 - Kachel, S. A1 - Balkenhol, N. T1 - Right on track? BT - Performance of satellite telemetry in terrestrial wildlife research JF - PLoS one N2 - Satellite telemetry is an increasingly utilized technology in wildlife research, and current devices can track individual animal movements at unprecedented spatial and temporal resolutions. However, as we enter the golden age of satellite telemetry, we need an in-depth understanding of the main technological, species-specific and environmental factors that determine the success and failure of satellite tracking devices across species and habitats. Here, we assess the relative influence of such factors on the ability of satellite telemetry units to provide the expected amount and quality of data by analyzing data from over 3,000 devices deployed on 62 terrestrial species in 167 projects worldwide. We evaluate the success rate in obtaining GPS fixes as well as in transferring these fixes to the user and we evaluate failure rates. Average fix success and data transfer rates were high and were generally better predicted by species and unit characteristics, while environmental characteristics influenced the variability of performance. However, 48% of the unit deployments ended prematurely, half of them due to technical failure. Nonetheless, this study shows that the performance of satellite telemetry applications has shown improvements over time, and based on our findings, we provide further recommendations for both users and manufacturers. Y1 - 2019 U6 - https://doi.org/10.1371/journal.pone.0216223 SN - 1932-6203 VL - 14 IS - 5 PB - PLoS CY - San Fransisco ER - TY - JOUR A1 - Thomas, Jessica E. A1 - Carvalho, Gary R. A1 - Haile, James A1 - Martin, Michael D. A1 - Castruita, Jose A. Samaniego A1 - Niemann, Jonas A1 - Sinding, Mikkel-Holger S. A1 - Sandoval-Velasco, Marcela A1 - Rawlence, Nicolas J. A1 - Fuller, Errol A1 - Fjeldsa, Jon A1 - Hofreiter, Michael A1 - Stewart, John R. A1 - Gilbert, M. Thomas P. A1 - Knapp, Michael T1 - An ‛Aukward’ tale BT - a genetic approach to discover the whereabouts of the Last Great Auks JF - Genes N2 - One hundred and seventy-three years ago, the last two Great Auks, Pinguinus impennis, ever reliably seen were killed. Their internal organs can be found in the collections of the Natural History Museum of Denmark, but the location of their skins has remained a mystery. In 1999, Great Auk expert Errol Fuller proposed a list of five potential candidate skins in museums around the world. Here we take a palaeogenomic approach to test which—if any—of Fuller’s candidate skins likely belong to either of the two birds. Using mitochondrial genomes from the five candidate birds (housed in museums in Bremen, Brussels, Kiel, Los Angeles, and Oldenburg) and the organs of the last two known individuals, we partially solve the mystery that has been on Great Auk scholars’ minds for generations and make new suggestions as to the whereabouts of the still-missing skin from these two birds. KW - ancient DNA KW - extinct birds KW - mitochondrial genome KW - museum specimens KW - palaeogenomics Y1 - 2017 U6 - https://doi.org/10.3390/genes8060164 SN - 2073-4425 VL - 8 IS - 6 SP - 164 PB - MDPI CY - Basel ER - TY - JOUR A1 - Ikram, M. Arfan A1 - Fornage, Myriam A1 - Smith, Albert V. A1 - Seshadri, Sudha A1 - Schmidt, Reinhold A1 - Debette, Stephanie A1 - Vrooman, Henri A. A1 - Sigurdsson, Sigurdur A1 - Ropele, Stefan A1 - Taal, H. Rob A1 - Mook-Kanamori, Dennis O. A1 - Coker, Laura H. A1 - Longstreth, W. T. A1 - Niessen, Wiro J. A1 - DeStefano, Anita L. A1 - Beiser, Alexa A1 - Zijdenbos, Alex P. A1 - Struchalin, Maksim A1 - Jack, Clifford R. A1 - Rivadeneira, Fernando A1 - Uitterlinden, Andre G. A1 - Knopman, David S. A1 - Hartikainen, Anna-Liisa A1 - Pennell, Craig E. A1 - Thiering, Elisabeth A1 - Steegers, Eric A. P. A1 - Hakonarson, Hakon A1 - Heinrich, Joachim A1 - Palmer, Lyle J. A1 - Jarvelin, Marjo-Riitta A1 - McCarthy, Mark I. A1 - Grant, Struan F. A. A1 - St Pourcain, Beate A1 - Timpson, Nicholas J. A1 - Smith, George Davey A1 - Sovio, Ulla A1 - Nalls, Mike A. A1 - Au, Rhoda A1 - Hofman, Albert A1 - Gudnason, Haukur A1 - van der Lugt, Aad A1 - Harris, Tamara B. A1 - Meeks, William M. A1 - Vernooij, Meike W. A1 - van Buchem, Mark A. A1 - Catellier, Diane A1 - Jaddoe, Vincent W. V. A1 - Gudnason, Vilmundur A1 - Windham, B. Gwen A1 - Wolf, Philip A. A1 - van Duijn, Cornelia M. A1 - Mosley, Thomas H. A1 - Schmidt, Helena A1 - Launer, Lenore J. A1 - Breteler, Monique M. B. A1 - DeCarli, Charles A1 - Adair, Linda S. A1 - Ang, Wei A1 - Atalay, Mustafa A1 - vanBeijsterveldt, Toos A1 - Bergen, Nienke A1 - Benke, Kelly A1 - Berry, Diane J. A1 - Coin, Lachlan A1 - Davis, Oliver S. P. A1 - Elliott, Paul A1 - Flexeder, Claudia A1 - Frayling, Tim A1 - Gaillard, Romy A1 - Groen-Blokhuis, Maria A1 - Goh, Liang-Kee A1 - Haworth, Claire M. A. A1 - Hadley, Dexter A1 - Hebebrand, Johannes A1 - Hinney, Anke A1 - Hirschhorn, Joel N. A1 - Holloway, John W. A1 - Holst, Claus A1 - Hottenga, Jouke Jan A1 - Horikoshi, Momoko A1 - Huikari, Ville A1 - Hypponen, Elina A1 - Kilpelainen, Tuomas O. A1 - Kirin, Mirna A1 - Kowgier, Matthew A1 - Lakka, Hanna-Maaria A1 - Lange, Leslie A. A1 - Lawlor, Debbie A. A1 - Lehtimaki, Terho A1 - Lewin, Alex A1 - Lindgren, Cecilia A1 - Lindi, Virpi A1 - Maggi, Reedik A1 - Marsh, Julie A1 - Middeldorp, Christel A1 - Millwood, Iona A1 - Murray, Jeffrey C. A1 - Nivard, Michel A1 - Nohr, Ellen Aagaard A1 - Ntalla, Ioanna A1 - Oken, Emily A1 - Panoutsopoulou, Kalliope A1 - Pararajasingham, Jennifer A1 - Rodriguez, Alina A1 - Salem, Rany M. A1 - Sebert, Sylvain A1 - Siitonen, Niina A1 - Strachan, David P. A1 - Teo, Yik-Ying A1 - Valcarcel, Beatriz A1 - Willemsen, Gonneke A1 - Zeggini, Eleftheria A1 - Boomsma, Dorret I. A1 - Cooper, Cyrus A1 - Gillman, Matthew A1 - Hocher, Berthold A1 - Lakka, Timo A. A1 - Mohlke, Karen L. A1 - Dedoussis, George V. A1 - Ong, Ken K. A1 - Pearson, Ewan R. A1 - Price, Thomas S. A1 - Power, Chris A1 - Raitakari, Olli T. A1 - Saw, Seang-Mei A1 - Scherag, Andre A1 - Simell, Olli A1 - Sorensen, Thorkild I. A. A1 - Wilson, James F. T1 - Common variants at 6q22 and 17q21 are associated with intracranial volume JF - Nature genetics N2 - During aging, intracranial volume remains unchanged and represents maximally attained brain size, while various interacting biological phenomena lead to brain volume loss. Consequently, intracranial volume and brain volume in late life reflect different genetic influences. Our genome-wide association study (GWAS) in 8,175 community-dwelling elderly persons did not reveal any associations at genome-wide significance (P < 5 x 10(-8)) for brain volume. In contrast, intracranial volume was significantly associated with two loci: rs4273712 (P = 3.4 x 10(-11)), a known height-associated locus on chromosome 6q22, and rs9915547 (P = 1.5 x 10(-12)), localized to the inversion on chromosome 17q21. We replicated the associations of these loci with intracranial volume in a separate sample of 1,752 elderly persons (P = 1.1 x 10(-3) for 6q22 and 1.2 x 10(-3) for 17q21). Furthermore, we also found suggestive associations of the 17q21 locus with head circumference in 10,768 children (mean age of 14.5 months). Our data identify two loci associated with head size, with the inversion at 17q21 also likely to be involved in attaining maximal brain size. Y1 - 2012 U6 - https://doi.org/10.1038/ng.2245 SN - 1061-4036 VL - 44 IS - 5 SP - 539 EP - + PB - Nature Publ. Group CY - New York ER - TY - JOUR A1 - Tucker, Marlee A. A1 - Boehning-Gaese, Katrin A1 - Fagan, William F. A1 - Fryxell, John M. A1 - Van Moorter, Bram A1 - Alberts, Susan C. A1 - Ali, Abdullahi H. A1 - Allen, Andrew M. A1 - Attias, Nina A1 - Avgar, Tal A1 - Bartlam-Brooks, Hattie A1 - Bayarbaatar, Buuveibaatar A1 - Belant, Jerrold L. A1 - Bertassoni, Alessandra A1 - Beyer, Dean A1 - Bidner, Laura A1 - van Beest, Floris M. A1 - Blake, Stephen A1 - Blaum, Niels A1 - Bracis, Chloe A1 - Brown, Danielle A1 - de Bruyn, P. J. Nico A1 - Cagnacci, Francesca A1 - Calabrese, Justin M. A1 - Camilo-Alves, Constanca A1 - Chamaille-Jammes, Simon A1 - Chiaradia, Andre A1 - Davidson, Sarah C. A1 - Dennis, Todd A1 - DeStefano, Stephen A1 - Diefenbach, Duane A1 - Douglas-Hamilton, Iain A1 - Fennessy, Julian A1 - Fichtel, Claudia A1 - Fiedler, Wolfgang A1 - Fischer, Christina A1 - Fischhoff, Ilya A1 - Fleming, Christen H. A1 - Ford, Adam T. A1 - Fritz, Susanne A. A1 - Gehr, Benedikt A1 - Goheen, Jacob R. A1 - Gurarie, Eliezer A1 - Hebblewhite, Mark A1 - Heurich, Marco A1 - Hewison, A. J. Mark A1 - Hof, Christian A1 - Hurme, Edward A1 - Isbell, Lynne A. A1 - Janssen, Rene A1 - Jeltsch, Florian A1 - Kaczensky, Petra A1 - Kane, Adam A1 - Kappeler, Peter M. A1 - Kauffman, Matthew A1 - Kays, Roland A1 - Kimuyu, Duncan A1 - Koch, Flavia A1 - Kranstauber, Bart A1 - LaPoint, Scott A1 - Leimgruber, Peter A1 - Linnell, John D. C. A1 - Lopez-Lopez, Pascual A1 - Markham, A. Catherine A1 - Mattisson, Jenny A1 - Medici, Emilia Patricia A1 - Mellone, Ugo A1 - Merrill, Evelyn A1 - Mourao, Guilherme de Miranda A1 - Morato, Ronaldo G. A1 - Morellet, Nicolas A1 - Morrison, Thomas A. A1 - Diaz-Munoz, Samuel L. A1 - Mysterud, Atle A1 - Nandintsetseg, Dejid A1 - Nathan, Ran A1 - Niamir, Aidin A1 - Odden, John A1 - Oliveira-Santos, Luiz Gustavo R. A1 - Olson, Kirk A. A1 - Patterson, Bruce D. A1 - de Paula, Rogerio Cunha A1 - Pedrotti, Luca A1 - Reineking, Bjorn A1 - Rimmler, Martin A1 - Rogers, Tracey L. A1 - Rolandsen, Christer Moe A1 - Rosenberry, Christopher S. A1 - Rubenstein, Daniel I. A1 - Safi, Kamran A1 - Said, Sonia A1 - Sapir, Nir A1 - Sawyer, Hall A1 - Schmidt, Niels Martin A1 - Selva, Nuria A1 - Sergiel, Agnieszka A1 - Shiilegdamba, Enkhtuvshin A1 - Silva, Joao Paulo A1 - Singh, Navinder A1 - Solberg, Erling J. A1 - Spiegel, Orr A1 - Strand, Olav A1 - Sundaresan, Siva A1 - Ullmann, Wiebke A1 - Voigt, Ulrich A1 - Wall, Jake A1 - Wattles, David A1 - Wikelski, Martin A1 - Wilmers, Christopher C. A1 - Wilson, John W. A1 - Wittemyer, George A1 - Zieba, Filip A1 - Zwijacz-Kozica, Tomasz A1 - Mueller, Thomas T1 - Moving in the Anthropocene BT - global reductions in terrestrial mammalian movements JF - Science N2 - Animal movement is fundamental for ecosystem functioning and species survival, yet the effects of the anthropogenic footprint on animal movements have not been estimated across species. Using a unique GPS-tracking database of 803 individuals across 57 species, we found that movements of mammals in areas with a comparatively high human footprint were on average one-half to one-third the extent of their movements in areas with a low human footprint. We attribute this reduction to behavioral changes of individual animals and to the exclusion of species with long-range movements from areas with higher human impact. Global loss of vagility alters a key ecological trait of animals that affects not only population persistence but also ecosystem processes such as predator-prey interactions, nutrient cycling, and disease transmission. Y1 - 2018 U6 - https://doi.org/10.1126/science.aam9712 SN - 0036-8075 SN - 1095-9203 VL - 359 IS - 6374 SP - 466 EP - 469 PB - American Assoc. for the Advancement of Science CY - Washington ER - TY - JOUR A1 - Noonan, Michael J. A1 - Tucker, Marlee A. A1 - Fleming, Christen H. A1 - Akre, Thomas S. A1 - Alberts, Susan C. A1 - Ali, Abdullahi H. A1 - Altmann, Jeanne A1 - Antunes, Pamela Castro A1 - Belant, Jerrold L. A1 - Beyer, Dean A1 - Blaum, Niels A1 - Boehning-Gaese, Katrin A1 - Cullen Jr, Laury A1 - de Paula, Rogerio Cunha A1 - Dekker, Jasja A1 - Drescher-Lehman, Jonathan A1 - Farwig, Nina A1 - Fichtel, Claudia A1 - Fischer, Christina A1 - Ford, Adam T. A1 - Goheen, Jacob R. A1 - Janssen, Rene A1 - Jeltsch, Florian A1 - Kauffman, Matthew A1 - Kappeler, Peter M. A1 - Koch, Flavia A1 - LaPoint, Scott A1 - Markham, A. Catherine A1 - Medici, Emilia Patricia A1 - Morato, Ronaldo G. A1 - Nathan, Ran A1 - Oliveira-Santos, Luiz Gustavo R. A1 - Olson, Kirk A. A1 - Patterson, Bruce D. A1 - Paviolo, Agustin A1 - Ramalho, Emiliano Estero A1 - Rosner, Sascha A1 - Schabo, Dana G. A1 - Selva, Nuria A1 - Sergiel, Agnieszka A1 - da Silva, Marina Xavier A1 - Spiegel, Orr A1 - Thompson, Peter A1 - Ullmann, Wiebke A1 - Zieba, Filip A1 - Zwijacz-Kozica, Tomasz A1 - Fagan, William F. A1 - Mueller, Thomas A1 - Calabrese, Justin M. T1 - A comprehensive analysis of autocorrelation and bias in home range estimation JF - Ecological monographs : a publication of the Ecological Society of America. N2 - Home range estimation is routine practice in ecological research. While advances in animal tracking technology have increased our capacity to collect data to support home range analysis, these same advances have also resulted in increasingly autocorrelated data. Consequently, the question of which home range estimator to use on modern, highly autocorrelated tracking data remains open. This question is particularly relevant given that most estimators assume independently sampled data. Here, we provide a comprehensive evaluation of the effects of autocorrelation on home range estimation. We base our study on an extensive data set of GPS locations from 369 individuals representing 27 species distributed across five continents. We first assemble a broad array of home range estimators, including Kernel Density Estimation (KDE) with four bandwidth optimizers (Gaussian reference function, autocorrelated‐Gaussian reference function [AKDE], Silverman's rule of thumb, and least squares cross‐validation), Minimum Convex Polygon, and Local Convex Hull methods. Notably, all of these estimators except AKDE assume independent and identically distributed (IID) data. We then employ half‐sample cross‐validation to objectively quantify estimator performance, and the recently introduced effective sample size for home range area estimation ( N̂ area ) to quantify the information content of each data set. We found that AKDE 95% area estimates were larger than conventional IID‐based estimates by a mean factor of 2. The median number of cross‐validated locations included in the hold‐out sets by AKDE 95% (or 50%) estimates was 95.3% (or 50.1%), confirming the larger AKDE ranges were appropriately selective at the specified quantile. Conversely, conventional estimates exhibited negative bias that increased with decreasing N̂ area. To contextualize our empirical results, we performed a detailed simulation study to tease apart how sampling frequency, sampling duration, and the focal animal's movement conspire to affect range estimates. Paralleling our empirical results, the simulation study demonstrated that AKDE was generally more accurate than conventional methods, particularly for small N̂ area. While 72% of the 369 empirical data sets had >1,000 total observations, only 4% had an N̂ area >1,000, where 30% had an N̂ area <30. In this frequently encountered scenario of small N̂ area, AKDE was the only estimator capable of producing an accurate home range estimate on autocorrelated data. KW - animal movement KW - kernel density estimation KW - local convex hull KW - minimum convex polygon KW - range distribution KW - space use KW - telemetry KW - tracking data Y1 - 2018 U6 - https://doi.org/10.1002/ecm.1344 SN - 0012-9615 SN - 1557-7015 VL - 89 IS - 2 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Kupfer, Thomas A1 - Bauer, Evan B. A1 - van Roestel, Jan A1 - Bellm, Eric C. A1 - Bildsten, Lars A1 - Fuller, Jim A1 - Prince, Thomas A. A1 - Heber, Ulrich A1 - Geier, Stephan A1 - Green, Matthew J. A1 - Kulkarni, Shrinivas R. A1 - Bloemen, Steven A1 - Laher, Russ R. A1 - Rusholme, Ben A1 - Schneider, David T1 - Discovery of a Double-detonation Thermonuclear Supernova Progenitor JF - The astrophysical journal : an international review of spectroscopy and astronomical physics ; Part 2, Letters N2 - We present the discovery of a new double-detonation progenitor system consisting of a hot subdwarf B (sdB) binary with a white dwarf companion with a P (orb) = 76.34179(2) minutes orbital period. Spectroscopic observations are consistent with an sdB star during helium core burning residing on the extreme horizontal branch. Chimera light curves are dominated by ellipsoidal deformation of the sdB star and a weak eclipse of the companion white dwarf. Combining spectroscopic and light curve fits, we find a low-mass sdB star, M (sdB) = 0.383 +/- 0.028 M (circle dot) with a massive white dwarf companion, M (WD) = 0.725 +/- 0.026 M (circle dot). From the eclipses we find a blackbody temperature for the white dwarf of 26,800 K resulting in a cooling age of approximate to 25 Myr whereas our MESA model predicts an sdB age of approximate to 170 Myr. We conclude that the sdB formed first through stable mass transfer followed by a common envelope which led to the formation of the white dwarf companion approximate to 25 Myr ago. Using the MESA stellar evolutionary code we find that the sdB star will start mass transfer in approximate to 6 Myr and in approximate to 60 Myr the white dwarf will reach a total mass of 0.92 M (circle dot) with a thick helium layer of 0.17 M (circle dot). This will lead to a detonation that will likely destroy the white dwarf in a peculiar thermonuclear supernova. PTF1 J2238+7430 is only the second confirmed candidate for a double-detonation thermonuclear supernova. Using both systems we estimate that at least approximate to 1% of white dwarf thermonuclear supernovae originate from sdB+WD binaries with thick helium layers, consistent with the small number of observed peculiar thermonuclear explosions. Y1 - 2022 U6 - https://doi.org/10.3847/2041-8213/ac48f1 SN - 2041-8205 SN - 2041-8213 VL - 925 IS - 2 PB - IOP Publ. Ltd. CY - Bristol ER - TY - GEN A1 - Gorski, Mathias A1 - Jung, Bettina A1 - Li, Yong A1 - Matias-Garcia, Pamela R. A1 - Wuttke, Matthias A1 - Coassin, Stefan A1 - Thio, Chris H. L. A1 - Kleber, Marcus E. A1 - Winkler, Thomas W. A1 - Wanner, Veronika A1 - Chai, Jin-Fang A1 - Chu, Audrey Y. A1 - Cocca, Massimiliano A1 - Feitosa, Mary F. A1 - Ghasemi, Sahar A1 - Hoppmann, Anselm A1 - Horn, Katrin A1 - Li, Man A1 - Nutile, Teresa A1 - Scholz, Markus A1 - Sieber, Karsten B. A1 - Teumer, Alexander A1 - Tin, Adrienne A1 - Wang, Judy A1 - Tayo, Bamidele O. A1 - Ahluwalia, Tarunveer S. A1 - Almgren, Peter A1 - Bakker, Stephan J. L. A1 - Banas, Bernhard A1 - Bansal, Nisha A1 - Biggs, Mary L. A1 - Boerwinkle, Eric A1 - Böttinger, Erwin A1 - Brenner, Hermann A1 - Carroll, Robert J. A1 - Chalmers, John A1 - Chee, Miao-Li A1 - Chee, Miao-Ling A1 - Cheng, Ching-Yu A1 - Coresh, Josef A1 - de Borst, Martin H. A1 - Degenhardt, Frauke A1 - Eckardt, Kai-Uwe A1 - Endlich, Karlhans A1 - Franke, Andre A1 - Freitag-Wolf, Sandra A1 - Gampawar, Piyush A1 - Gansevoort, Ron T. A1 - Ghanbari, Mohsen A1 - Gieger, Christian A1 - Hamet, Pavel A1 - Ho, Kevin A1 - Hofer, Edith A1 - Holleczek, Bernd A1 - Foo, Valencia Hui Xian A1 - Hutri-Kahonen, Nina A1 - Hwang, Shih-Jen A1 - Ikram, M. Arfan A1 - Josyula, Navya Shilpa A1 - Kahonen, Mika A1 - Khor, Chiea-Chuen A1 - Koenig, Wolfgang A1 - Kramer, Holly A1 - Kraemer, Bernhard K. A1 - Kuehnel, Brigitte A1 - Lange, Leslie A. A1 - Lehtimaki, Terho A1 - Lieb, Wolfgang A1 - Loos, Ruth J. F. A1 - Lukas, Mary Ann A1 - Lyytikainen, Leo-Pekka A1 - Meisinger, Christa A1 - Meitinger, Thomas A1 - Melander, Olle A1 - Milaneschi, Yuri A1 - Mishra, Pashupati P. A1 - Mononen, Nina A1 - Mychaleckyj, Josyf C. A1 - Nadkarni, Girish N. A1 - Nauck, Matthias A1 - Nikus, Kjell A1 - Ning, Boting A1 - Nolte, Ilja M. A1 - O'Donoghue, Michelle L. A1 - Orho-Melander, Marju A1 - Pendergrass, Sarah A. A1 - Penninx, Brenda W. J. H. A1 - Preuss, Michael H. A1 - Psaty, Bruce M. A1 - Raffield, Laura M. A1 - Raitakari, Olli T. A1 - Rettig, Rainer A1 - Rheinberger, Myriam A1 - Rice, Kenneth M. A1 - Rosenkranz, Alexander R. A1 - Rossing, Peter A1 - Rotter, Jerome A1 - Sabanayagam, Charumathi A1 - Schmidt, Helena A1 - Schmidt, Reinhold A1 - Schoettker, Ben A1 - Schulz, Christina-Alexandra A1 - Sedaghat, Sanaz A1 - Shaffer, Christian M. A1 - Strauch, Konstantin A1 - Szymczak, Silke A1 - Taylor, Kent D. A1 - Tremblay, Johanne A1 - Chaker, Layal A1 - van der Harst, Pim A1 - van der Most, Peter J. A1 - Verweij, Niek A1 - Voelker, Uwe A1 - Waldenberger, Melanie A1 - Wallentin, Lars A1 - Waterworth, Dawn M. A1 - White, Harvey D. A1 - Wilson, James G. A1 - Wong, Tien-Yin A1 - Woodward, Mark A1 - Yang, Qiong A1 - Yasuda, Masayuki A1 - Yerges-Armstrong, Laura M. A1 - Zhang, Yan A1 - Snieder, Harold A1 - Wanner, Christoph A1 - Boger, Carsten A. A1 - Kottgen, Anna A1 - Kronenberg, Florian A1 - Pattaro, Cristian A1 - Heid, Iris M. T1 - Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline T2 - Zweitveröffentlichungen der Universität Potsdam : Reihe der Digital Engineering Fakultät N2 - Rapid decline of glomerular filtration rate estimated from creatinine (eGFRcrea) is associated with severe clinical endpoints. In contrast to cross-sectionally assessed eGFRcrea, the genetic basis for rapid eGFRcrea decline is largely unknown. To help define this, we meta-analyzed 42 genome-wide association studies from the Chronic Kidney Diseases Genetics Consortium and United Kingdom Biobank to identify genetic loci for rapid eGFRcrea decline. Two definitions of eGFRcrea decline were used: 3 mL/min/1.73m(2)/year or more ("Rapid3"; encompassing 34,874 cases, 107,090 controls) and eGFRcrea decline 25% or more and eGFRcrea under 60 mL/min/1.73m(2) at follow-up among those with eGFRcrea 60 mL/min/1.73m(2) or more at baseline ("CKDi25"; encompassing 19,901 cases, 175,244 controls). Seven independent variants were identified across six loci for Rapid3 and/or CKDi25: consisting of five variants at four loci with genome-wide significance (near UMOD-PDILT (2), PRKAG2, WDR72, OR2S2) and two variants among 265 known eGFRcrea variants (near GATM, LARP4B). All these loci were novel for Rapid3 and/or CKDi25 and our bioinformatic follow-up prioritized variants and genes underneath these loci. The OR2S2 locus is novel for any eGFRcrea trait including interesting candidates. For the five genome-wide significant lead variants, we found supporting effects for annual change in blood urea nitrogen or cystatin-based eGFR, but not for GATM or (LARP4B). Individuals at high compared to those at low genetic risk (8-14 vs. 0-5 adverse alleles) had a 1.20-fold increased risk of acute kidney injury (95% confidence interval 1.08-1.33). Thus, our identified loci for rapid kidney function decline may help prioritize therapeutic targets and identify mechanisms and individuals at risk for sustained deterioration of kidney function. T3 - Zweitveröffentlichungen der Universität Potsdam : Reihe der Digital Engineering Fakultät - 19 KW - acute kidney injury KW - end-stage kidney disease KW - genome-wide association KW - study KW - rapid eGFRcrea decline Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-565379 IS - 19 ER - TY - JOUR A1 - Gorski, Mathias A1 - Jung, Bettina A1 - Li, Yong A1 - Matias-Garcia, Pamela R. A1 - Wuttke, Matthias A1 - Coassin, Stefan A1 - Thio, Chris H. L. A1 - Kleber, Marcus E. A1 - Winkler, Thomas W. A1 - Wanner, Veronika A1 - Chai, Jin-Fang A1 - Chu, Audrey Y. A1 - Cocca, Massimiliano A1 - Feitosa, Mary F. A1 - Ghasemi, Sahar A1 - Hoppmann, Anselm A1 - Horn, Katrin A1 - Li, Man A1 - Nutile, Teresa A1 - Scholz, Markus A1 - Sieber, Karsten B. A1 - Teumer, Alexander A1 - Tin, Adrienne A1 - Wang, Judy A1 - Tayo, Bamidele O. A1 - Ahluwalia, Tarunveer S. A1 - Almgren, Peter A1 - Bakker, Stephan J. L. A1 - Banas, Bernhard A1 - Bansal, Nisha A1 - Biggs, Mary L. A1 - Boerwinkle, Eric A1 - Böttinger, Erwin A1 - Brenner, Hermann A1 - Carroll, Robert J. A1 - Chalmers, John A1 - Chee, Miao-Li A1 - Chee, Miao-Ling A1 - Cheng, Ching-Yu A1 - Coresh, Josef A1 - de Borst, Martin H. A1 - Degenhardt, Frauke A1 - Eckardt, Kai-Uwe A1 - Endlich, Karlhans A1 - Franke, Andre A1 - Freitag-Wolf, Sandra A1 - Gampawar, Piyush A1 - Gansevoort, Ron T. A1 - Ghanbari, Mohsen A1 - Gieger, Christian A1 - Hamet, Pavel A1 - Ho, Kevin A1 - Hofer, Edith A1 - Holleczek, Bernd A1 - Foo, Valencia Hui Xian A1 - Hutri-Kahonen, Nina A1 - Hwang, Shih-Jen A1 - Ikram, M. Arfan A1 - Josyula, Navya Shilpa A1 - Kahonen, Mika A1 - Khor, Chiea-Chuen A1 - Koenig, Wolfgang A1 - Kramer, Holly A1 - Kraemer, Bernhard K. A1 - Kuehnel, Brigitte A1 - Lange, Leslie A. A1 - Lehtimaki, Terho A1 - Lieb, Wolfgang A1 - Loos, Ruth J. F. A1 - Lukas, Mary Ann A1 - Lyytikainen, Leo-Pekka A1 - Meisinger, Christa A1 - Meitinger, Thomas A1 - Melander, Olle A1 - Milaneschi, Yuri A1 - Mishra, Pashupati P. A1 - Mononen, Nina A1 - Mychaleckyj, Josyf C. A1 - Nadkarni, Girish N. A1 - Nauck, Matthias A1 - Nikus, Kjell A1 - Ning, Boting A1 - Nolte, Ilja M. A1 - O'Donoghue, Michelle L. A1 - Orho-Melander, Marju A1 - Pendergrass, Sarah A. A1 - Penninx, Brenda W. J. H. A1 - Preuss, Michael H. A1 - Psaty, Bruce M. A1 - Raffield, Laura M. A1 - Raitakari, Olli T. A1 - Rettig, Rainer A1 - Rheinberger, Myriam A1 - Rice, Kenneth M. A1 - Rosenkranz, Alexander R. A1 - Rossing, Peter A1 - Rotter, Jerome A1 - Sabanayagam, Charumathi A1 - Schmidt, Helena A1 - Schmidt, Reinhold A1 - Schoettker, Ben A1 - Schulz, Christina-Alexandra A1 - Sedaghat, Sanaz A1 - Shaffer, Christian M. A1 - Strauch, Konstantin A1 - Szymczak, Silke A1 - Taylor, Kent D. A1 - Tremblay, Johanne A1 - Chaker, Layal A1 - van der Harst, Pim A1 - van der Most, Peter J. A1 - Verweij, Niek A1 - Voelker, Uwe A1 - Waldenberger, Melanie A1 - Wallentin, Lars A1 - Waterworth, Dawn M. A1 - White, Harvey D. A1 - Wilson, James G. A1 - Wong, Tien-Yin A1 - Woodward, Mark A1 - Yang, Qiong A1 - Yasuda, Masayuki A1 - Yerges-Armstrong, Laura M. A1 - Zhang, Yan A1 - Snieder, Harold A1 - Wanner, Christoph A1 - Boger, Carsten A. A1 - Kottgen, Anna A1 - Kronenberg, Florian A1 - Pattaro, Cristian A1 - Heid, Iris M. T1 - Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline JF - Kidney international : official journal of the International Society of Nephrology N2 - Rapid decline of glomerular filtration rate estimated from creatinine (eGFRcrea) is associated with severe clinical endpoints. In contrast to cross-sectionally assessed eGFRcrea, the genetic basis for rapid eGFRcrea decline is largely unknown. To help define this, we meta-analyzed 42 genome-wide association studies from the Chronic Kidney Diseases Genetics Consortium and United Kingdom Biobank to identify genetic loci for rapid eGFRcrea decline. Two definitions of eGFRcrea decline were used: 3 mL/min/1.73m(2)/year or more ("Rapid3"; encompassing 34,874 cases, 107,090 controls) and eGFRcrea decline 25% or more and eGFRcrea under 60 mL/min/1.73m(2) at follow-up among those with eGFRcrea 60 mL/min/1.73m(2) or more at baseline ("CKDi25"; encompassing 19,901 cases, 175,244 controls). Seven independent variants were identified across six loci for Rapid3 and/or CKDi25: consisting of five variants at four loci with genome-wide significance (near UMOD-PDILT (2), PRKAG2, WDR72, OR2S2) and two variants among 265 known eGFRcrea variants (near GATM, LARP4B). All these loci were novel for Rapid3 and/or CKDi25 and our bioinformatic follow-up prioritized variants and genes underneath these loci. The OR2S2 locus is novel for any eGFRcrea trait including interesting candidates. For the five genome-wide significant lead variants, we found supporting effects for annual change in blood urea nitrogen or cystatin-based eGFR, but not for GATM or (LARP4B). Individuals at high compared to those at low genetic risk (8-14 vs. 0-5 adverse alleles) had a 1.20-fold increased risk of acute kidney injury (95% confidence interval 1.08-1.33). Thus, our identified loci for rapid kidney function decline may help prioritize therapeutic targets and identify mechanisms and individuals at risk for sustained deterioration of kidney function. KW - acute kidney injury KW - end-stage kidney disease KW - genome-wide association KW - study KW - rapid eGFRcrea decline Y1 - 2020 U6 - https://doi.org/10.1016/j.kint.2020.09.030 SN - 0085-2538 SN - 1523-1755 VL - 99 IS - 4 SP - 926 EP - 939 PB - Elsevier CY - New York ER - TY - JOUR A1 - Seroussi, Helene A1 - Nowicki, Sophie A1 - Payne, Antony J. A1 - Goelzer, Heiko A1 - Lipscomb, William H. A1 - Abe-Ouchi, Ayako A1 - Agosta, Cecile A1 - Albrecht, Torsten A1 - Asay-Davis, Xylar A1 - Barthel, Alice A1 - Calov, Reinhard A1 - Cullather, Richard A1 - Dumas, Christophe A1 - Galton-Fenzi, Benjamin K. A1 - Gladstone, Rupert A1 - Golledge, Nicholas R. A1 - Gregory, Jonathan M. A1 - Greve, Ralf A1 - Hattermann, Tore A1 - Hoffman, Matthew J. A1 - Humbert, Angelika A1 - Huybrechts, Philippe A1 - Jourdain, Nicolas C. A1 - Kleiner, Thomas A1 - Larour, Eric A1 - Leguy, Gunter R. A1 - Lowry, Daniel P. A1 - Little, Chistopher M. A1 - Morlighem, Mathieu A1 - Pattyn, Frank A1 - Pelle, Tyler A1 - Price, Stephen F. A1 - Quiquet, Aurelien A1 - Reese, Ronja A1 - Schlegel, Nicole-Jeanne A1 - Shepherd, Andrew A1 - Simon, Erika A1 - Smith, Robin S. A1 - Straneo, Fiammetta A1 - Sun, Sainan A1 - Trusel, Luke D. A1 - Van Breedam, Jonas A1 - van de Wal, Roderik S. W. A1 - Winkelmann, Ricarda A1 - Zhao, Chen A1 - Zhang, Tong A1 - Zwinger, Thomas T1 - ISMIP6 Antarctica BT - a multi-model ensemble of the Antarctic ice sheet evolution over the 21st century JF - The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union N2 - Ice flow models of the Antarctic ice sheet are commonly used to simulate its future evolution in response to different climate scenarios and assess the mass loss that would contribute to future sea level rise. However, there is currently no consensus on estimates of the future mass balance of the ice sheet, primarily because of differences in the representation of physical processes, forcings employed and initial states of ice sheet models. This study presents results from ice flow model simulations from 13 international groups focusing on the evolution of the Antarctic ice sheet during the period 2015-2100 as part of the Ice Sheet Model Intercomparison for CMIP6 (ISMIP6). They are forced with outputs from a subset of models from the Coupled Model Intercomparison Project Phase 5 (CMIP5), representative of the spread in climate model results. Simulations of the Antarctic ice sheet contribution to sea level rise in response to increased warming during this period varies between 7:8 and 30.0 cm of sea level equivalent (SLE) under Representative Concentration Pathway (RCP) 8.5 scenario forcing. These numbers are relative to a control experiment with constant climate conditions and should therefore be added to the mass loss contribution under climate conditions similar to present-day conditions over the same period. The simulated evolution of the West Antarctic ice sheet varies widely among models, with an overall mass loss, up to 18.0 cm SLE, in response to changes in oceanic conditions. East Antarctica mass change varies between 6 :1 and 8.3 cm SLE in the simulations, with a significant increase in surface mass balance outweighing the increased ice discharge under most RCP 8.5 scenario forcings. The inclusion of ice shelf collapse, here assumed to be caused by large amounts of liquid water ponding at the surface of ice shelves, yields an additional simulated mass loss of 28mm compared to simulations without ice shelf collapse. The largest sources of uncertainty come from the climate forcing, the ocean-induced melt rates, the calibration of these melt rates based on oceanic conditions taken outside of ice shelf cavities and the ice sheet dynamic response to these oceanic changes. Results under RCP 2.6 scenario based on two CMIP5 climate models show an additional mass loss of 0 and 3 cm of SLE on average compared to simulations done under present-day conditions for the two CMIP5 forcings used and display limited mass gain in East Antarctica. Y1 - 2020 U6 - https://doi.org/10.5194/tc-14-3033-2020 SN - 1994-0416 SN - 1994-0424 VL - 14 IS - 9 SP - 3033 EP - 3070 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Hetenyi, Gyorgy A1 - Molinari, Irene A1 - Clinton, John A1 - Bokelmann, Gotz A1 - Bondar, Istvan A1 - Crawford, Wayne C. A1 - Dessa, Jean-Xavier A1 - Doubre, Cecile A1 - Friederich, Wolfgang A1 - Fuchs, Florian A1 - Giardini, Domenico A1 - Graczer, Zoltan A1 - Handy, Mark R. A1 - Herak, Marijan A1 - Jia, Yan A1 - Kissling, Edi A1 - Kopp, Heidrun A1 - Korn, Michael A1 - Margheriti, Lucia A1 - Meier, Thomas A1 - Mucciarelli, Marco A1 - Paul, Anne A1 - Pesaresi, Damiano A1 - Piromallo, Claudia A1 - Plenefisch, Thomas A1 - Plomerova, Jaroslava A1 - Ritter, Joachim A1 - Rumpker, Georg A1 - Sipka, Vesna A1 - Spallarossa, Daniele A1 - Thomas, Christine A1 - Tilmann, Frederik A1 - Wassermann, Joachim A1 - Weber, Michael A1 - Weber, Zoltan A1 - Wesztergom, Viktor A1 - Zivcic, Mladen A1 - Abreu, Rafael A1 - Allegretti, Ivo A1 - Apoloner, Maria-Theresia A1 - Aubert, Coralie A1 - Besancon, Simon A1 - de Berc, Maxime Bes A1 - Brunel, Didier A1 - Capello, Marco A1 - Carman, Martina A1 - Cavaliere, Adriano A1 - Cheze, Jerome A1 - Chiarabba, Claudio A1 - Cougoulat, Glenn A1 - Cristiano, Luigia A1 - Czifra, Tibor A1 - Danesi, Stefania A1 - Daniel, Romuald A1 - Dannowski, Anke A1 - Dasovic, Iva A1 - Deschamps, Anne A1 - Egdorf, Sven A1 - Fiket, Tomislav A1 - Fischer, Kasper A1 - Funke, Sigward A1 - Govoni, Aladino A1 - Groschl, Gidera A1 - Heimers, Stefan A1 - Heit, Ben A1 - Herak, Davorka A1 - Huber, Johann A1 - Jaric, Dejan A1 - Jedlicka, Petr A1 - Jund, Helene A1 - Klingen, Stefan A1 - Klotz, Bernhard A1 - Kolinsky, Petr A1 - Kotek, Josef A1 - Kuhne, Lothar A1 - Kuk, Kreso A1 - Lange, Dietrich A1 - Loos, Jurgen A1 - Lovati, Sara A1 - Malengros, Deny A1 - Maron, Christophe A1 - Martin, Xavier A1 - Massa, Marco A1 - Mazzarini, Francesco A1 - Metral, Laurent A1 - Moretti, Milena A1 - Munzarova, Helena A1 - Nardi, Anna A1 - Pahor, Jurij A1 - Pequegnat, Catherine A1 - Petersen, Florian A1 - Piccinini, Davide A1 - Pondrelli, Silvia A1 - Prevolnik, Snjezan A1 - Racine, Roman A1 - Regnier, Marc A1 - Reiss, Miriam A1 - Salimbeni, Simone A1 - Santulin, Marco A1 - Scherer, Werner A1 - Schippkus, Sven A1 - Schulte-Kortnack, Detlef A1 - Solarino, Stefano A1 - Spieker, Kathrin A1 - Stipcevic, Josip A1 - Strollo, Angelo A1 - Sule, Balint A1 - Szanyi, Gyongyver A1 - Szucs, Eszter A1 - Thorwart, Martin A1 - Ueding, Stefan A1 - Vallocchia, Massimiliano A1 - Vecsey, Ludek A1 - Voigt, Rene A1 - Weidle, Christian A1 - Weyland, Gauthier A1 - Wiemer, Stefan A1 - Wolf, Felix A1 - Wolyniec, David A1 - Zieke, Thomas T1 - The AlpArray seismic network BT - a large-scale european experiment to image the alpine orogen JF - Surveys in Geophysics N2 - The AlpArray programme is a multinational, European consortium to advance our understanding of orogenesis and its relationship to mantle dynamics, plate reorganizations, surface processes and seismic hazard in the Alps-Apennines-Carpathians-Dinarides orogenic system. The AlpArray Seismic Network has been deployed with contributions from 36 institutions from 11 countries to map physical properties of the lithosphere and asthenosphere in 3D and thus to obtain new, high-resolution geophysical images of structures from the surface down to the base of the mantle transition zone. With over 600 broadband stations operated for 2 years, this seismic experiment is one of the largest simultaneously operated seismological networks in the academic domain, employing hexagonal coverage with station spacing at less than 52 km. This dense and regularly spaced experiment is made possible by the coordinated coeval deployment of temporary stations from numerous national pools, including ocean-bottom seismometers, which were funded by different national agencies. They combine with permanent networks, which also required the cooperation of many different operators. Together these stations ultimately fill coverage gaps. Following a short overview of previous large-scale seismological experiments in the Alpine region, we here present the goals, construction, deployment, characteristics and data management of the AlpArray Seismic Network, which will provide data that is expected to be unprecedented in quality to image the complex Alpine mountains at depth. KW - Seismology KW - Alps KW - Seismic network KW - Geodynamics KW - Seismic imaging KW - Mountain building Y1 - 2018 U6 - https://doi.org/10.1007/s10712-018-9472-4 SN - 0169-3298 SN - 1573-0956 VL - 39 IS - 5 SP - 1009 EP - 1033 PB - Springer CY - Dordrecht ER - TY - RPRT A1 - Brodeur, Abel A1 - Mikola, Derek A1 - Cook, Nikolai A1 - Brailey, Thomas A1 - Briggs, Ryan A1 - Gendre, Alexandra de A1 - Dupraz, Yannick A1 - Fiala, Lenka A1 - Gabani, Jacopo A1 - Gauriot, Romain A1 - Haddad, Joanne A1 - Lima, Goncalo A1 - Ankel-Peters, Jörg A1 - Dreber, Anna A1 - Campbell, Douglas A1 - Kattan, Lamis A1 - Fages, Diego Marino A1 - Mierisch, Fabian A1 - Sun, Pu A1 - Wright, Taylor A1 - Connolly, Marie A1 - Hoces de la Guardia, Fernando A1 - Johannesson, Magnus A1 - Miguel, Edward A1 - Vilhuber, Lars A1 - Abarca, Alejandro A1 - Acharya, Mahesh A1 - Adjisse, Sossou Simplice A1 - Akhtar, Ahwaz A1 - Lizardi, Eduardo Alberto Ramirez A1 - Albrecht, Sabina A1 - Andersen, Synve Nygaard A1 - Andlib, Zubaria A1 - Arrora, Falak A1 - Ash, Thomas A1 - Bacher, Etienne A1 - Bachler, Sebastian A1 - Bacon, Félix A1 - Bagues, Manuel A1 - Balogh, Timea A1 - Batmanov, Alisher A1 - Barschkett, Mara A1 - Basdil, B. Kaan A1 - Dower, Jaromneda A1 - Castek, Ondrej A1 - Caviglia-Harris, Jill A1 - Strand, Gabriella Chauca A1 - Chen, Shi A1 - Chzhen, Asya A1 - Chung, Jong A1 - Collins, Jason A1 - Coppock, Alexander A1 - Cordeau, Hugo A1 - Couillard, Ben A1 - Crechet, Jonathan A1 - Crippa, Lorenzo A1 - Cui, Jeanne A1 - Czymara, Christian A1 - Daarstad, Haley A1 - Dao, Danh Chi A1 - Dao, Dong A1 - Schmandt, Marco David A1 - Linde, Astrid de A1 - Melo, Lucas De A1 - Deer, Lachlan A1 - Vera, Micole De A1 - Dimitrova, Velichka A1 - Dollbaum, Jan Fabian A1 - Dollbaum, Jan Matti A1 - Donnelly, Michael A1 - Huynh, Luu Duc Toan A1 - Dumbalska, Tsvetomira A1 - Duncan, Jamie A1 - Duong, Kiet Tuan A1 - Duprey, Thibaut A1 - Dworschak, Christoph A1 - Ellingsrud, Sigmund A1 - Elminejad, Ali A1 - Eissa, Yasmine A1 - Erhart, Andrea A1 - Etingin-Frati, Giulian A1 - Fatemi-Pour, Elaheh A1 - Federice, Alexa A1 - Feld, Jan A1 - Fenig, Guidon A1 - Firouzjaeiangalougah, Mojtaba A1 - Fleisje, Erlend A1 - Fortier-Chouinard, Alexandre A1 - Engel, Julia Francesca A1 - Fries, Tilman A1 - Fortier, Reid A1 - Fréchet, Nadjim A1 - Galipeau, Thomas A1 - Gallegos, Sebastián A1 - Gangji, Areez A1 - Gao, Xiaoying A1 - Garnache, Cloé A1 - Gáspár, Attila A1 - Gavrilova, Evelina A1 - Ghosh, Arijit A1 - Gibney, Garreth A1 - Gibson, Grant A1 - Godager, Geir A1 - Goff, Leonard A1 - Gong, Da A1 - González, Javier A1 - Gretton, Jeremy A1 - Griffa, Cristina A1 - Grigoryeva, Idaliya A1 - Grtting, Maja A1 - Guntermann, Eric A1 - Guo, Jiaqi A1 - Gugushvili, Alexi A1 - Habibnia, Hooman A1 - Häffner, Sonja A1 - Hall, Jonathan D. A1 - Hammar, Olle A1 - Kordt, Amund Hanson A1 - Hashimoto, Barry A1 - Hartley, Jonathan S. A1 - Hausladen, Carina I. A1 - Havránek, Tomáš A1 - Hazen, Jacob A1 - He, Harry A1 - Hepplewhite, Matthew A1 - Herrera-Rodriguez, Mario A1 - Heuer, Felix A1 - Heyes, Anthony A1 - Ho, Anson T. Y. A1 - Holmes, Jonathan A1 - Holzknecht, Armando A1 - Hsu, Yu-Hsiang Dexter A1 - Hu, Shiang-Hung A1 - Huang, Yu-Shiuan A1 - Huebener, Mathias A1 - Huber, Christoph A1 - Huynh, Kim P. A1 - Irsova, Zuzana A1 - Isler, Ozan A1 - Jakobsson, Niklas A1 - Frith, Michael James A1 - Jananji, Raphaël A1 - Jayalath, Tharaka A. A1 - Jetter, Michael A1 - John, Jenny A1 - Forshaw, Rachel Joy A1 - Juan, Felipe A1 - Kadriu, Valon A1 - Karim, Sunny A1 - Kelly, Edmund A1 - Dang, Duy Khanh Hoang A1 - Khushboo, Tazia A1 - Kim, Jin A1 - Kjellsson, Gustav A1 - Kjelsrud, Anders A1 - Kotsadam, Andreas A1 - Korpershoek, Jori A1 - Krashinsky, Lewis A1 - Kundu, Suranjana A1 - Kustov, Alexander A1 - Lalayev, Nurlan A1 - Langlois, Audrée A1 - Laufer, Jill A1 - Lee-Whiting, Blake A1 - Leibing, Andreas A1 - Lenz, Gabriel A1 - Levin, Joel A1 - Li, Peng A1 - Li, Tongzhe A1 - Lin, Yuchen A1 - Listo, Ariel A1 - Liu, Dan A1 - Lu, Xuewen A1 - Lukmanova, Elvina A1 - Luscombe, Alex A1 - Lusher, Lester R. A1 - Lyu, Ke A1 - Ma, Hai A1 - Mäder, Nicolas A1 - Makate, Clifton A1 - Malmberg, Alice A1 - Maitra, Adit A1 - Mandas, Marco A1 - Marcus, Jan A1 - Margaryan, Shushanik A1 - Márk, Lili A1 - Martignano, Andres A1 - Marsh, Abigail A1 - Masetto, Isabella A1 - McCanny, Anthony A1 - McManus, Emma A1 - McWay, Ryan A1 - Metson, Lennard A1 - Kinge, Jonas Minet A1 - Mishra, Sumit A1 - Mohnen, Myra A1 - Möller, Jakob A1 - Montambeault, Rosalie A1 - Montpetit, Sébastien A1 - Morin, Louis-Philippe A1 - Morris, Todd A1 - Moser, Scott A1 - Motoki, Fabio A1 - Muehlenbachs, Lucija A1 - Musulan, Andreea A1 - Musumeci, Marco A1 - Nabin, Munirul A1 - Nchare, Karim A1 - Neubauer, Florian A1 - Nguyen, Quan M. P. A1 - Nguyen, Tuan A1 - Nguyen-Tien, Viet A1 - Niazi, Ali A1 - Nikolaishvili, Giorgi A1 - Nordstrom, Ardyn A1 - Nü, Patrick A1 - Odermatt, Angela A1 - Olson, Matt A1 - ien, Henning A1 - Ölkers, Tim A1 - Vert, Miquel Oliver i. A1 - Oral, Emre A1 - Oswald, Christian A1 - Ousman, Ali A1 - Özak, Ömer A1 - Pandey, Shubham A1 - Pavlov, Alexandre A1 - Pelli, Martino A1 - Penheiro, Romeo A1 - Park, RyuGyung A1 - Martel, Eva Pérez A1 - Petrovičová, Tereza A1 - Phan, Linh A1 - Prettyman, Alexa A1 - Procházka, Jakub A1 - Putri, Aqila A1 - Quandt, Julian A1 - Qiu, Kangyu A1 - Nguyen, Loan Quynh Thi A1 - Rahman, Andaleeb A1 - Rea, Carson H. A1 - Reiremo, Adam A1 - Renée, Laëtitia A1 - Richardson, Joseph A1 - Rivers, Nicholas A1 - Rodrigues, Bruno A1 - Roelofs, William A1 - Roemer, Tobias A1 - Rogeberg, Ole A1 - Rose, Julian A1 - Roskos-Ewoldsen, Andrew A1 - Rosmer, Paul A1 - Sabada, Barbara A1 - Saberian, Soodeh A1 - Salamanca, Nicolas A1 - Sator, Georg A1 - Sawyer, Antoine A1 - Scates, Daniel A1 - Schlüter, Elmar A1 - Sells, Cameron A1 - Sen, Sharmi A1 - Sethi, Ritika A1 - Shcherbiak, Anna A1 - Sogaolu, Moyosore A1 - Soosalu, Matt A1 - Srensen, Erik A1 - Sovani, Manali A1 - Spencer, Noah A1 - Staubli, Stefan A1 - Stans, Renske A1 - Stewart, Anya A1 - Stips, Felix A1 - Stockley, Kieran A1 - Strobel, Stephenson A1 - Struby, Ethan A1 - Tang, John A1 - Tanrisever, Idil A1 - Yang, Thomas Tao A1 - Tastan, Ipek A1 - Tatić, Dejan A1 - Tatlow, Benjamin A1 - Seuyong, Féraud Tchuisseu A1 - Thériault, Rémi A1 - Thivierge, Vincent A1 - Tian, Wenjie A1 - Toma, Filip-Mihai A1 - Totarelli, Maddalena A1 - Tran, Van-Anh A1 - Truong, Hung A1 - Tsoy, Nikita A1 - Tuzcuoglu, Kerem A1 - Ubfal, Diego A1 - Villalobos, Laura A1 - Walterskirchen, Julian A1 - Wang, Joseph Taoyi A1 - Wattal, Vasudha A1 - Webb, Matthew D. A1 - Weber, Bryan A1 - Weisser, Reinhard A1 - Weng, Wei-Chien A1 - Westheide, Christian A1 - White, Kimberly A1 - Winter, Jacob A1 - Wochner, Timo A1 - Woerman, Matt A1 - Wong, Jared A1 - Woodard, Ritchie A1 - Wroński, Marcin A1 - Yazbeck, Myra A1 - Yang, Gustav Chung A1 - Yap, Luther A1 - Yassin, Kareman A1 - Ye, Hao A1 - Yoon, Jin Young A1 - Yurris, Chris A1 - Zahra, Tahreen A1 - Zaneva, Mirela A1 - Zayat, Aline A1 - Zhang, Jonathan A1 - Zhao, Ziwei A1 - Yaolang, Zhong T1 - Mass reproducibility and replicability BT - a new hope T2 - I4R discussion paper series N2 - This study pushes our understanding of research reliability by reproducing and replicating claims from 110 papers in leading economic and political science journals. The analysis involves computational reproducibility checks and robustness assessments. It reveals several patterns. First, we uncover a high rate of fully computationally reproducible results (over 85%). Second, excluding minor issues like missing packages or broken pathways, we uncover coding errors for about 25% of studies, with some studies containing multiple errors. Third, we test the robustness of the results to 5,511 re-analyses. We find a robustness reproducibility of about 70%. Robustness reproducibility rates are relatively higher for re-analyses that introduce new data and lower for re-analyses that change the sample or the definition of the dependent variable. Fourth, 52% of re-analysis effect size estimates are smaller than the original published estimates and the average statistical significance of a re-analysis is 77% of the original. Lastly, we rely on six teams of researchers working independently to answer eight additional research questions on the determinants of robustness reproducibility. Most teams find a negative relationship between replicators' experience and reproducibility, while finding no relationship between reproducibility and the provision of intermediate or even raw data combined with the necessary cleaning codes. KW - conomics KW - open science KW - political science KW - replication KW - reproduction KW - research transparency Y1 - 2024 SN - 2752-1931 IS - 107 PB - Institute for Replication CY - Essen ER - TY - JOUR A1 - Sonkajärvi, Hanna A1 - Rogge, Jörg A1 - Demura, Shin A1 - Fichte, Robby A1 - Alkämper, Urte Christine A1 - Tischer, Anuschka A1 - Wollschläger, Thomas A1 - Prass, Reiner A1 - Helmedach, Andreas A1 - Kubetzky, Thomas A1 - Mehrkens, Heidi A1 - Kater, Thomas A1 - Sawilla, Jan Marco A1 - Schneider, Dorit A1 - Ueberschär, Ellen A1 - Angelow, Jürgen A1 - Muth, Jörg A1 - Lang, Heinrich A1 - Kroll, Stefan A1 - Kroener, Bernhard R. A1 - Pröve, Ralf A1 - Hollberg, Cecilie T1 - Militär und Gesellschaft in der Frühen Neuzeit N2 - Aus dem Inhalt dieser Ausgabe: BEITRÄGE: Hanna Sonkajärvi: Soldaten als Fremde in Straßburg im 18. Jahrhundert, Jörg Rogge: Das Kriegswesen im späten Mittelalter und seine Erforschung: neuere englische und deutsche Arbeiten zu Krieg, Staat und Gesellschaft, PROJEKTE: Shin Demura: Allso hiebe der innere krieg schon an, der vil Erger dann der eüssere war : die Stadt als Zufluchtsort für Flüchtlinge : Erfahrungsformen des Dreißigjährigen Krieges in der Reichsstadt Ulm und ihrer Region, Robby Fichte: Zur Entwicklungsgeschichte des öffentlich-rechtlichen Vertrages anhand der Begründung des Militärdienstverhältnisses 1650-1914, Urte Christine Allkämper: Die Braut des Soldaten : symbolische Kommunikation mit der Waffe von der Frühen Neuzeit bis zur Gegenwart, Anuschka Tischer: Offizielle Kriegsbegründungen in der frühen Neuzeit - Funktionen, Formen, Inhalte, Thomas Wollschläger: Die Military Revolution und der deutsche Territorialstaat unter besonderer Berücksichtigung Brandenburg-Preußens und Sachsens : Determinanten der Staatskonsolidierung im europäischen Kontext 1670-1740, BERICHTE: Reiner Prass: Tagungsbericht Gewalt in der Frühen Neuzeit : 5. Tagung der Arbeitsgemeinschaft Frühe Neuzeit vom 18. bis 20. September 2003 an der Freien Universität Berlin, Andreas Helmedach, Thomas Kubetzky, Heidi Mehrkens: Tilly ist nur eine Chiffre, die es aufzulösen gilt ... - Jahrestagung des Arbeitskreises Militärgeschichte: Soldat und Gesellschaft : Biographien und Selbstzeugnisse in der Militärgeschichte 10.-11. Oktober 2003, Thomas Kater: Bericht über die Jahrestagung des Arbeitskreises Historische Friedensforschung : Der Friede ist keine leere Idee ... - Bilder und Vorstellungen vom Frieden im langen 19. Jahrhundert, 31.10. bis 2.11.2003, Stiftung Adam von Trott, Imshausen, Jan Marco Sawilla: Religion und Krieg - Bericht über die Hamburger Gespräche zur Geschichtswissenschaft (V III.) WS 2003/ 2004, Dorit Schneider: Kriegsbegründungen in der Geschichte. Strategien der Legitimierung und Legalisierung militärischer Gewalt - 30.-31.01.2004, Deutscher Bundestag, Berlin, REZENSIONEN: Ellen Ueberschär: Das Strafgericht Gottes : Kriegserfahrungen und Religion im Heiligen Römischen Reich Deutscher Nation im Zeitalter des Dreißigjährigen Krieges, hrsg. von Matthias Asche und Anton Schindling, Münster 2001, Jürgen Angelow: Jutta Nowosadtko: Krieg, Gewalt und Ordnung : Einführung in die Militärgeschichte, Tübingen 2002, Jörg Muth: John A. Lynn: Battle - A History of Combat and Culture from Ancient Greece to Modern Amerika, Boulder 2003, Heinrich Lang: Del Treppo, Mario (H g.): Condottieri e uomini d arme nell Italia del Rinascimento. Acura e con un saggio introduttivo di Mario Del Treppo, Napoli 2001, Stefan Kroll: Jörg Muth, Flucht aus dem militärischen Alltag : Ursachen und individuelle Ausprägung der Desertion in der Armee Friedrichs des Großen. Mit besonderer Berücksichtigung der Infanterie-Regimenter der Potsdamer Garnison, Freiburg i. Br. 2003, ANKÜNDIGUNGEN: Bernhard R. Kroener, Ralf Pröve: Tempi passati! Der Arbeitskreis Militär und Gesellschaft in der Frühen Neuzeit : ein Zwischenbericht nach einem Jahrzehnt, Mitgliederversammlung 2004, AMG-Tagung 2007, Cecilie Hollberg: Glaube & Macht : Sachsen im Europa der Reformationszeit ; die 2. Sächsische Landesausstellung ; die Schlacht bei Mühlberg : Ausgang und Folgen T3 - Militär und Gesellschaft in der frühen Neuzeit - 8, Heft 1 KW - Militär / Geschichte Y1 - 2004 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-6765 SN - 1617-9722 SN - 1861-910X VL - 8 IS - 1 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Wolf, Thomas J. A. A1 - Sanchez, David M. A1 - Yang, J. A1 - Parrish, R. M. A1 - Nunes, J. P. F. A1 - Centurion, M. A1 - Coffee, R. A1 - Cryan, J. P. A1 - Gühr, Markus A1 - Hegazy, Kareem A1 - Kirrander, Adam A1 - Li, R. K. A1 - Ruddock, J. A1 - Shen, Xiaozhe A1 - Vecchione, T. A1 - Weathersby, S. P. A1 - Weber, Peter M. A1 - Wilkin, K. A1 - Yong, Haiwang A1 - Zheng, Q. A1 - Wang, X. J. A1 - Minitti, Michael P. A1 - Martinez, Todd J. T1 - The photochemical ring-opening of 1,3-cyclohexadiene imaged by ultrafast electron diffraction JF - Nature chemistry N2 - The ultrafast photoinduced ring-opening of 1,3-cyclohexadiene constitutes a textbook example of electrocyclic reactions in organic chemistry and a model for photobiological reactions in vitamin D synthesis. Although the relaxation from the photoexcited electronic state during the ring-opening has been investigated in numerous studies, the accompanying changes in atomic distance have not been resolved. Here we present a direct and unambiguous observation of the ring-opening reaction path on the femtosecond timescale and subangstrom length scale using megaelectronvolt ultrafast electron diffraction. We followed the carbon-carbon bond dissociation and the structural opening of the 1,3-cyclohexadiene ring by the direct measurement of time-dependent changes in the distribution of interatomic distances. We observed a substantial acceleration of the ring-opening motion after internal conversion to the ground state due to a steepening of the electronic potential gradient towards the product minima. The ring-opening motion transforms into rotation of the terminal ethylene groups in the photoproduct 1,3,5-hexatriene on the subpicosecond timescale. KW - Organic chemistry KW - Photochemistry KW - Physical chemistry KW - Theoretical chemistry Y1 - 2019 U6 - https://doi.org/10.1038/s41557-019-0252-7 SN - 1755-4330 SN - 1755-4349 VL - 11 IS - 6 SP - 504 EP - 509 PB - Nature Publ. Group CY - London ER - TY - JOUR A1 - Arnison, Paul G. A1 - Bibb, Mervyn J. A1 - Bierbaum, Gabriele A1 - Bowers, Albert A. A1 - Bugni, Tim S. A1 - Bulaj, Grzegorz A1 - Camarero, Julio A. A1 - Campopiano, Dominic J. A1 - Challis, Gregory L. A1 - Clardy, Jon A1 - Cotter, Paul D. A1 - Craik, David J. A1 - Dawson, Michael A1 - Dittmann-Thünemann, Elke A1 - Donadio, Stefano A1 - Dorrestein, Pieter C. A1 - Entian, Karl-Dieter A1 - Fischbach, Michael A. A1 - Garavelli, John S. A1 - Goeransson, Ulf A1 - Gruber, Christian W. A1 - Haft, Daniel H. A1 - Hemscheidt, Thomas K. A1 - Hertweck, Christian A1 - Hill, Colin A1 - Horswill, Alexander R. A1 - Jaspars, Marcel A1 - Kelly, Wendy L. A1 - Klinman, Judith P. A1 - Kuipers, Oscar P. A1 - Link, A. James A1 - Liu, Wen A1 - Marahiel, Mohamed A. A1 - Mitchell, Douglas A. A1 - Moll, Gert N. A1 - Moore, Bradley S. A1 - Mueller, Rolf A1 - Nair, Satish K. A1 - Nes, Ingolf F. A1 - Norris, Gillian E. A1 - Olivera, Baldomero M. A1 - Onaka, Hiroyasu A1 - Patchett, Mark L. A1 - Piel, Jörn A1 - Reaney, Martin J. T. A1 - Rebuffat, Sylvie A1 - Ross, R. Paul A1 - Sahl, Hans-Georg A1 - Schmidt, Eric W. A1 - Selsted, Michael E. A1 - Severinov, Konstantin A1 - Shen, Ben A1 - Sivonen, Kaarina A1 - Smith, Leif A1 - Stein, Torsten A1 - Suessmuth, Roderich D. A1 - Tagg, John R. A1 - Tang, Gong-Li A1 - Truman, Andrew W. A1 - Vederas, John C. A1 - Walsh, Christopher T. A1 - Walton, Jonathan D. A1 - Wenzel, Silke C. A1 - Willey, Joanne M. A1 - van der Donk, Wilfred A. T1 - Ribosomally synthesized and post-translationally modified peptide natural products overview and recommendations for a universal nomenclature JF - Natural product reports : a journal of current developments in bio-organic chemistry N2 - This review presents recommended nomenclature for the biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPPs), a rapidly growing class of natural products. The current knowledge regarding the biosynthesis of the >20 distinct compound classes is also reviewed, and commonalities are discussed. Y1 - 2013 U6 - https://doi.org/10.1039/c2np20085f SN - 0265-0568 VL - 30 IS - 1 SP - 108 EP - 160 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Martin, Nicolas F. A1 - Nidever, David L. A1 - Besla, Gurtina A1 - Olsen, Knut A1 - Walker, Alistair R. A1 - Vivas, A. Katherina A1 - Gruendl, Robert A. A1 - Kaleida, Catherine C. A1 - Munoz, Ricardo R. A1 - Blum, Robert D. A1 - Saha, Abhijit A1 - Conn, Blair C. A1 - Bell, Eric F. A1 - Chu, You-Hua A1 - Cioni, Maria-Rosa L. A1 - de Boer, Thomas J. L. A1 - Gallart, Carme A1 - Jin, Shoko A1 - Kunder, Andrea A1 - Majewski, Steven R. A1 - Martinez-Delgado, David A1 - Monachesi, Antonela A1 - Monelli, Matteo A1 - Monteagudo, Lara A1 - Noel, Noelia E. D. A1 - Olszewski, Edward W. A1 - Stringfellow, Guy S. A1 - van der Marel, Roeland P. A1 - Zaritsky, Dennis T1 - Hydra II: A faint and compact milky way dwarf galaxy found in the survey of the magellanic stellar history JF - The astrophysical journal : an international review of spectroscopy and astronomical physics ; Part 2, Letters N2 - We present the discovery of a new dwarf galaxy, Hydra II, found serendipitously within the data from the ongoing Survey of the Magellanic Stellar History conducted with the Dark Energy Camera on the Blanco 4 m Telescope. The new satellite is compact (r(h) = 68 +/- 11 pc) and faint (MV = -4.8 +/- 0.3), but well within the realm of dwarf galaxies. The stellar distribution of Hydra II in the color-magnitude diagram is well-described by a metal-poor ([Fe/H] = -2.2) and old (13 Gyr) isochrone and shows a distinct blue horizontal branch, some possible red clump stars, and faint stars that are suggestive of blue stragglers. At a heliocentric distance of 134 +/- 10 kpc, Hydra II is located in a region of the Galactic halo that models have suggested may host material from the leading arm of the Magellanic Stream. A comparison with N-body simulations hints that the new dwarf galaxy could be or could have been a satellite of the Magellanic Clouds. KW - galaxies: individual (Hydra II) KW - Local Group KW - Magellanic Clouds Y1 - 2015 U6 - https://doi.org/10.1088/2041-8205/804/1/L5 SN - 2041-8205 SN - 2041-8213 VL - 804 IS - 1 PB - IOP Publ. Ltd. CY - Bristol ER -