TY  - JOUR
A1  - Warrington, Nicole
A1  - Beaumont, Robin
A1  - Horikoshi, Momoko
A1  - Day, Felix R.
A1  - Helgeland, Øyvind
A1  - Laurin, Charles
A1  - Bacelis, Jonas
A1  - Peng, Shouneng
A1  - Hao, Ke
A1  - Feenstra, Bjarke
A1  - Wood, Andrew R.
A1  - Mahajan, Anubha
A1  - Tyrrell, Jessica
A1  - Robertson, Neil R.
A1  - Rayner, N. William
A1  - Qiao, Zhen
A1  - Moen, Gunn-Helen
A1  - Vaudel, Marc
A1  - Marsit, Carmen
A1  - Chen, Jia
A1  - Nodzenski, Michael
A1  - Schnurr, Theresia M.
A1  - Zafarmand, Mohammad Hadi
A1  - Bradfield, Jonathan P.
A1  - Grarup, Niels
A1  - Kooijman, Marjolein N.
A1  - Li-Gao, Ruifang
A1  - Geller, Frank
A1  - Ahluwalia, Tarunveer Singh
A1  - Paternoster, Lavinia
A1  - Rueedi, Rico
A1  - Huikari, Ville
A1  - Hottenga, Jouke-Jan
A1  - Lyytikäinen, Leo-Pekka
A1  - Cavadino, Alana
A1  - Metrustry, Sarah
A1  - Cousminer, Diana L.
A1  - Wu, Ying
A1  - Thiering, Elisabeth Paula
A1  - Wang, Carol A.
A1  - Have, Christian Theil
A1  - Vilor-Tejedor, Natalia
A1  - Joshi, Peter K.
A1  - Painter, Jodie N.
A1  - Ntalla, Ioanna
A1  - Myhre, Ronny
A1  - Pitkänen, Niina
A1  - van Leeuwen, Elisabeth M.
A1  - Joro, Raimo
A1  - Lagou, Vasiliki
A1  - Richmond, Rebecca C.
A1  - Espinosa, Ana
A1  - Barton, Sheila J.
A1  - Inskip, Hazel M.
A1  - Holloway, John W.
A1  - Santa-Marina, Loreto
A1  - Estivill, Xavier
A1  - Ang, Wei
A1  - Marsh, Julie A.
A1  - Reichetzeder, Christoph
A1  - Marullo, Letizia
A1  - Hocher, Berthold
A1  - Lunetta, Kathryn L.
A1  - Murabito, Joanne M.
A1  - Relton, Caroline L.
A1  - Kogevinas, Manolis
A1  - Chatzi, Leda
A1  - Allard, Catherine
A1  - Bouchard, Luigi
A1  - Hivert, Marie-France
A1  - Zhang, Ge
A1  - Muglia, Louis J.
A1  - Heikkinen, Jani
A1  - Morgen, Camilla S.
A1  - van Kampen, Antoine H. C.
A1  - van Schaik, Barbera D. C.
A1  - Mentch, Frank D.
A1  - Langenberg, Claudia
A1  - Scott, Robert A.
A1  - Zhao, Jing Hua
A1  - Hemani, Gibran
A1  - Ring, Susan M.
A1  - Bennett, Amanda J.
A1  - Gaulton, Kyle J.
A1  - Fernandez-Tajes, Juan
A1  - van Zuydam, Natalie R.
A1  - Medina-Gomez, Carolina
A1  - de Haan, Hugoline G.
A1  - Rosendaal, Frits R.
A1  - Kutalik, Zoltán
A1  - Marques-Vidal, Pedro
A1  - Das, Shikta
A1  - Willemsen, Gonneke
A1  - Mbarek, Hamdi
A1  - Müller-Nurasyid, Martina
A1  - Standl, Marie
A1  - Appel, Emil V. R.
A1  - Fonvig, Cilius Esmann
A1  - Trier, Caecilie
A1  - van Beijsterveldt, Catharina E. M.
A1  - Murcia, Mario
A1  - Bustamante, Mariona
A1  - Bonàs-Guarch, Sílvia
A1  - Hougaard, David M.
A1  - Mercader, Josep M.
A1  - Linneberg, Allan
A1  - Schraut, Katharina E.
A1  - Lind, Penelope A.
A1  - Medland, Sarah Elizabeth
A1  - Shields, Beverley M.
A1  - Knight, Bridget A.
A1  - Chai, Jin-Fang
A1  - Panoutsopoulou, Kalliope
A1  - Bartels, Meike
A1  - Sánchez, Friman
A1  - Stokholm, Jakob
A1  - Torrents, David
A1  - Vinding, Rebecca K.
A1  - Willems, Sara M.
A1  - Atalay, Mustafa
A1  - Chawes, Bo L.
A1  - Kovacs, Peter
A1  - Prokopenko, Inga
A1  - Tuke, Marcus A.
A1  - Yaghootkar, Hanieh
A1  - Ruth, Katherine S.
A1  - Jones, Samuel E.
A1  - Loh, Po-Ru
A1  - Murray, Anna
A1  - Weedon, Michael N.
A1  - Tönjes, Anke
A1  - Stumvoll, Michael
A1  - Michaelsen, Kim Fleischer
A1  - Eloranta, Aino-Maija
A1  - Lakka, Timo A.
A1  - van Duijn, Cornelia M.
A1  - Kiess, Wieland
A1  - Koerner, Antje
A1  - Niinikoski, Harri
A1  - Pahkala, Katja
A1  - Raitakari, Olli T.
A1  - Jacobsson, Bo
A1  - Zeggini, Eleftheria
A1  - Dedoussis, George V.
A1  - Teo, Yik-Ying
A1  - Saw, Seang-Mei
A1  - Montgomery, Grant W.
A1  - Campbell, Harry
A1  - Wilson, James F.
A1  - Vrijkotte, Tanja G. M.
A1  - Vrijheid, Martine
A1  - de Geus, Eco J. C. N.
A1  - Hayes, M. Geoffrey
A1  - Kadarmideen, Haja N.
A1  - Holm, Jens-Christian
A1  - Beilin, Lawrence J.
A1  - Pennell, Craig E.
A1  - Heinrich, Joachim
A1  - Adair, Linda S.
A1  - Borja, Judith B.
A1  - Mohlke, Karen L.
A1  - Eriksson, Johan G.
A1  - Widen, Elisabeth E.
A1  - Hattersley, Andrew T.
A1  - Spector, Tim D.
A1  - Kaehoenen, Mika
A1  - Viikari, Jorma S.
A1  - Lehtimaeki, Terho
A1  - Boomsma, Dorret I.
A1  - Sebert, Sylvain
A1  - Vollenweider, Peter
A1  - Sorensen, Thorkild I. A.
A1  - Bisgaard, Hans
A1  - Bonnelykke, Klaus
A1  - Murray, Jeffrey C.
A1  - Melbye, Mads
A1  - Nohr, Ellen A.
A1  - Mook-Kanamori, Dennis O.
A1  - Rivadeneira, Fernando
A1  - Hofman, Albert
A1  - Felix, Janine F.
A1  - Jaddoe, Vincent W. V.
A1  - Hansen, Torben
A1  - Pisinger, Charlotta
A1  - Vaag, Allan A.
A1  - Pedersen, Oluf
A1  - Uitterlinden, Andre G.
A1  - Jarvelin, Marjo-Riitta
A1  - Power, Christine
A1  - Hypponen, Elina
A1  - Scholtens, Denise M.
A1  - Lowe, William L.
A1  - Smith, George Davey
A1  - Timpson, Nicholas J.
A1  - Morris, Andrew P.
A1  - Wareham, Nicholas J.
A1  - Hakonarson, Hakon
A1  - Grant, Struan F. A.
A1  - Frayling, Timothy M.
A1  - Lawlor, Debbie A.
A1  - Njolstad, Pal R.
A1  - Johansson, Stefan
A1  - Ong, Ken K.
A1  - McCarthy, Mark I.
A1  - Perry, John R. B.
A1  - Evans, David M.
A1  - Freathy, Rachel M.
T1  - Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
JF  - Nature genetics
N2  - Birth weight variation is influenced by fetal and maternal genetic and non-genetic factors, and has been reproducibly associated with future cardio-metabolic health outcomes. In expanded genome-wide association analyses of own birth weight (n = 321,223) and offspring birth weight (n = 230,069 mothers), we identified 190 independent association signals (129 of which are novel). We used structural equation modeling to decompose the contributions of direct fetal and indirect maternal genetic effects, then applied Mendelian randomization to illuminate causal pathways. For example, both indirect maternal and direct fetal genetic effects drive the observational relationship between lower birth weight and higher later blood pressure: maternal blood pressure-raising alleles reduce offspring birth weight, but only direct fetal effects of these alleles, once inherited, increase later offspring blood pressure. Using maternal birth weight-lowering genotypes to proxy for an adverse intrauterine environment provided no evidence that it causally raises offspring blood pressure, indicating that the inverse birth weight-blood pressure association is attributable to genetic effects, and not to intrauterine programming.
Y1  - 2019
SN  - 1061-4036
SN  - 1546-1718
VL  - 51
IS  - 5
SP  - 804
EP  - +
PB  - Nature Publ. Group
CY  - New York
ER  - 
TY  - JOUR
A1  - Aliu, E.
A1  - Archambault, S.
A1  - Arlen, T.
A1  - Aune, T.
A1  - Beilicke, M.
A1  - Benbow, W.
A1  - Bouvier, A.
A1  - Buckley, J. H.
A1  - Bugaev, V.
A1  - Byrum, K.
A1  - Cesarini, A.
A1  - Ciupik, L.
A1  - Collins-Hughes, E.
A1  - Connolly, M. P.
A1  - Cui, W.
A1  - Dickherber, R.
A1  - Duke, C.
A1  - Dumm, J.
A1  - Falcone, A.
A1  - Federici, S.
A1  - Feng, Q.
A1  - Finley, J. P.
A1  - Finnegan, G.
A1  - Fortson, L.
A1  - Furniss, A.
A1  - Galante, N.
A1  - Gall, D.
A1  - Gillanders, G. H.
A1  - Godambe, S.
A1  - Griffin, S.
A1  - Grube, J.
A1  - Gyuk, G.
A1  - Hanna, D.
A1  - Holder, J.
A1  - Huan, H.
A1  - Hughes, G.
A1  - Humensky, T. B.
A1  - Kaaret, P.
A1  - Karlsson, N.
A1  - Khassen, Y.
A1  - Kieda, D.
A1  - Krawczynski, H.
A1  - Krennrich, F.
A1  - Lang, M. J.
A1  - LeBohec, S.
A1  - Lee, K.
A1  - Lyutikov, M.
A1  - Madhavan, A. S.
A1  - Maier, G.
A1  - Majumdar, P.
A1  - McArthur, S.
A1  - McCann, A.
A1  - Moriarty, P.
A1  - Mukherjee, R.
A1  - Nelson, T.
A1  - de Bhroithe, A. O'Faolain
A1  - Ong, R. A.
A1  - Orr, M.
A1  - Otte, A. N.
A1  - Park, N.
A1  - Perkins, J. S.
A1  - Pohl, M.
A1  - Prokoph, H.
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Reyes, L. C.
A1  - Reynolds, P. T.
A1  - Roache, E.
A1  - Saxon, D. B.
A1  - Schrödter, M.
A1  - Sembroski, G. H.
A1  - Sentuerk, G. D.
A1  - Smith, A. W.
A1  - Staszak, D.
A1  - Telezhinsky, Igor O.
A1  - Tesic, G.
A1  - Theiling, M.
A1  - Thibadeau, S.
A1  - Tsurusaki, K.
A1  - Varlotta, A.
A1  - Vincent, S.
A1  - Vivier, M.
A1  - Wagner, R. G.
A1  - Wakely, S. P.
A1  - Weekes, T. C.
A1  - Weinstein, A.
A1  - Welsing, R.
A1  - Williams, D. A.
A1  - Zitzer, B.
A1  - Kondratiev, V.
T1  - SEARCH FOR A CORRELATION BETWEEN VERY-HIGH-ENERGY GAMMA RAYS AND GIANT RADIO PULSES IN THE CRAB PULSAR
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics
N2  - We present the results of a joint observational campaign between the Green Bank radio telescope and the VERITAS gamma-ray telescope, which searched for a correlation between the emission of very-high-energy (VHE) gamma rays (E-gamma > 150 GeV) and giant radio pulses (GRPs) from the Crab pulsar at 8.9 GHz. A total of 15,366 GRPs were recorded during 11.6 hr of simultaneous observations, which were made across four nights in 2008 December and in 2009 November and December. We searched for an enhancement of the pulsed gamma-ray emission within time windows placed around the arrival time of the GRP events. In total, eight different time windows with durations ranging from 0.033 ms to 72 s were positioned at three different locations relative to the GRP to search for enhanced gamma-ray emission which lagged, led, or was concurrent with, the GRP event. Furthermore, we performed separate searches on main pulse GRPs and interpulse GRPs and on the most energetic GRPs in our data sample. No significant enhancement of pulsed VHE emission was found in any of the preformed searches. We set upper limits of 5-10 times the average VHE flux of the Crab pulsar on the flux simultaneous with interpulse GRPs on single-rotation-period timescales. On similar to 8 s timescales around interpulse GRPs, we set an upper limit of 2-3 times the average VHE flux. Within the framework of recent models for pulsed VHE emission from the Crab pulsar, the expected VHE-GRP emission correlations are below the derived limits.
KW  - rays: stars
KW  - pulsars: individual: B0531+21
Y1  - 2012
U6  - https://doi.org/10.1088/0004-637X/760/2/136
SN  - 0004-637X
VL  - 760
IS  - 2
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Arlen, T.
A1  - Aune, T.
A1  - Beilicke, M.
A1  - Benbow, W.
A1  - Bouvier, A.
A1  - Buckley, J. H.
A1  - Bugaev, V.
A1  - Cesarini, A.
A1  - Ciupik, L.
A1  - Connolly, M. P.
A1  - Cui, W.
A1  - Dickherber, R.
A1  - Dumm, J.
A1  - Errando, M.
A1  - Falcone, A.
A1  - Federici, S.
A1  - Feng, Q.
A1  - Finley, J. P.
A1  - Finnegan, G.
A1  - Fortson, L.
A1  - Furniss, A.
A1  - Galante, N.
A1  - Gall, D.
A1  - Griffin, S.
A1  - Grube, J.
A1  - Gyuk, G.
A1  - Hanna, D.
A1  - Holder, J.
A1  - Humensky, T. B.
A1  - Kaaret, P.
A1  - Karlsson, N.
A1  - Kertzman, M.
A1  - Khassen, Y.
A1  - Kieda, D.
A1  - Krawczynski, H.
A1  - Krennrich, F.
A1  - Maier, G.
A1  - Moriarty, P.
A1  - Mukherjee, R.
A1  - Nelson, T.
A1  - de Bhroithe, A. O'Faolain
A1  - Ong, R. A.
A1  - Orr, M.
A1  - Park, N.
A1  - Perkins, J. S.
A1  - Pichel, A.
A1  - Pohl, Martin
A1  - Prokoph, H.
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Reyes, L. C.
A1  - Reynolds, P. T.
A1  - Roache, E.
A1  - Saxon, D. B.
A1  - Schroedter, M.
A1  - Sembroski, G. H.
A1  - Staszak, D.
A1  - Telezhinsky, Igor O.
A1  - Tesic, G.
A1  - Theiling, M.
A1  - Tsurusaki, K.
A1  - Varlotta, A.
A1  - Vincent, S.
A1  - Wakely, S. P.
A1  - Weekes, T. C.
A1  - Weinstein, A.
A1  - Welsing, R.
A1  - Williams, D. A.
A1  - Zitzer, B.
A1  - Jorstad, S. G.
A1  - MacDonald, N. R.
A1  - Marscher, A. P.
A1  - Smith, P. S.
A1  - Walker, R. C.
A1  - Hovatta, T.
A1  - Richards, J.
A1  - Max-Moerbeck, W.
A1  - Readhead, A.
A1  - Lister, M. L.
A1  - Kovalev, Y. Y.
A1  - Pushkarev, A. B.
A1  - Gurwell, M. A.
A1  - Lahteenmaki, A.
A1  - Nieppola, E.
A1  - Tornikoski, M.
A1  - Jarvela, E.
T1  - Rapid TeV Gamma-Ray flaring of bl lacertae
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics
N2  - We report on the detection of a very rapid TeV gamma-ray flare from BL Lacertae on 2011 June 28 with the Very Energetic Radiation Imaging Telescope Array System (VERITAS). The flaring activity was observed during a 34.6 minute exposure, when the integral flux above 200 GeV reached (3.4 +/- 0.6) x 10(-6) photons m(-2) s(-1), roughly 125% of the Crab Nebula flux measured by VERITAS. The light curve indicates that the observations missed the rising phase of the flare but covered a significant portion of the decaying phase. The exponential decay time was determined to be 13 +/- 4 minutes, making it one of the most rapid gamma-ray flares seen from a TeV blazar. The gamma-ray spectrum of BL Lacertae during the flare was soft, with a photon index of 3.6 +/- 0.4, which is in agreement with the measurement made previously by MAGIC in a lower flaring state. Contemporaneous radio observations of the source with the Very Long Baseline Array revealed the emergence of a new, superluminal component from the core around the time of the TeV gamma-ray flare, accompanied by changes in the optical polarization angle. Changes in flux also appear to have occurred at optical, UV, and GeV gamma-ray wavelengths at the time of the flare, although they are difficult to quantify precisely due to sparse coverage. A strong flare was seen at radio wavelengths roughly four months later, which might be related to the gamma-ray flaring activities. We discuss the implications of these multiwavelength results.
KW  - galaxies: active
KW  - galaxies: individual (BL Lacertae, VER J2202+422)
KW  - gamma rays: galaxies
Y1  - 2013
U6  - https://doi.org/10.1088/0004-637X/762/2/92
SN  - 0004-637X
VL  - 762
IS  - 2
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Aliu, E.
A1  - Archambault, S.
A1  - Arlen, T.
A1  - Aune, T.
A1  - Beilicke, M.
A1  - Benbow, W.
A1  - Bird, R.
A1  - Boettcher, Markus
A1  - Bouvier, A.
A1  - Bugaev, V.
A1  - Byrum, K.
A1  - Cesarini, A.
A1  - Ciupik, L.
A1  - Collins-Hughes, E.
A1  - Connolly, M. P.
A1  - Cui, W.
A1  - Dickherber, R.
A1  - Duke, C.
A1  - Dumm, J.
A1  - Errando, M.
A1  - Falcone, A.
A1  - Federici, Simone
A1  - Feng, Q.
A1  - Finley, J. P.
A1  - Finnegan, G.
A1  - Fortson, L.
A1  - Furniss, A.
A1  - Galante, N.
A1  - Gall, D.
A1  - Gillanders, G. H.
A1  - Griffin, S.
A1  - Grube, J.
A1  - Gyuk, G.
A1  - Hanna, D.
A1  - Holder, J.
A1  - Hughes, G.
A1  - Humensky, T. B.
A1  - Kaaret, P.
A1  - Kertzman, M.
A1  - Khassen, Y.
A1  - Kieda, D.
A1  - Krawczynski, H.
A1  - Krennrich, F.
A1  - Lang, M. J.
A1  - Madhavan, A. S.
A1  - Maier, G.
A1  - Majumdar, P.
A1  - McArthur, S.
A1  - McCann, A.
A1  - Moriarty, P.
A1  - Mukherjee, R.
A1  - Nelson, T.
A1  - de Bhroithe, A. O'Faolain
A1  - Ong, R. A.
A1  - Orr, M.
A1  - Otte, A. N.
A1  - Park, N.
A1  - Perkins, J. S.
A1  - Pichel, A.
A1  - Pohl, Martin
A1  - Popkow, A.
A1  - Prokoph, H.
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Reyes, L. C.
A1  - Reynolds, P. T.
A1  - Roache, E.
A1  - Saxon, D. B.
A1  - Schroedter, M.
A1  - Sembroski, G. H.
A1  - Skole, C.
A1  - Smith, A. W.
A1  - Staszak, D.
A1  - Telezhinsky, Igor O.
A1  - Theiling, M.
A1  - Tyler, J.
A1  - Varlotta, A.
A1  - Vassiliev, V. V.
A1  - Wakely, S. P.
A1  - Weekes, T. C.
A1  - Weinstein, A.
A1  - Welsing, R.
A1  - Williams, D. A.
A1  - Zitzer, B.
T1  - Multiwavelenght observations and modeling of 1ES 1959+650 in a low flux state
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics
N2  - We report on the VERITAS observations of the high-frequency peaked BL Lac object 1ES 1959+650 in the period 2007-2011. This source is detected at TeV energies by VERITAS at 16.4 standard deviation (sigma) significance in 7.6 hr of observation in a low flux state. A multiwavelength spectral energy distribution (SED) is constructed from contemporaneous data from VERITAS, Fermi-LAT, RXTE PCA, and Swift UVOT. Swift XRT data is not included in the SED due to a lack of simultaneous observations with VERITAS. In contrast to the orphan gamma-ray flare exhibited by this source in 2002, the X-ray flux of the source is found to vary by an order of magnitude, while other energy regimes exhibit less variable emission. A quasi-equilibrium synchrotron self-Compton model with an additional external radiation field is used to describe three SEDs corresponding to the lowest, highest, and average X-ray states. The variation in the X-ray spectrum is modeled by changing the electron injection spectral index, with minor adjustments of the kinetic luminosity in electrons. This scenario produces small-scale flux variability of the order of less than or similar to 2 in the high energy (E > 1MeV) and very high energy (E > 100 GeV) gamma-ray regimes, which is corroborated by the Fermi-LAT, VERITAS, and Whipple 10 m telescope light curves.
KW  - BL Lacertae objects: general
KW  - BL Lacertae objects: individual (1ES 1959+650=VER J1959+651)
KW  - galaxies: active
KW  - gamma rays: galaxies
Y1  - 2013
U6  - https://doi.org/10.1088/0004-637X/775/1/3
SN  - 0004-637X
VL  - 775
IS  - 1
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Middeldorp, Christel M.
A1  - Mahajan, Anubha
A1  - Horikoshi, Momoko
A1  - Robertson, Neil R.
A1  - Beaumont, Robin N.
A1  - Bradfield, Jonathan P.
A1  - Bustamante, Mariona
A1  - Cousminer, Diana L.
A1  - Day, Felix R.
A1  - De Silva, N. Maneka
A1  - Guxens, Monica
A1  - Mook-Kanamori, Dennis O.
A1  - St Pourcain, Beate
A1  - Warrington, Nicole M.
A1  - Adair, Linda S.
A1  - Ahlqvist, Emma
A1  - Ahluwalia, Tarunveer Singh
A1  - Almgren, Peter
A1  - Ang, Wei
A1  - Atalay, Mustafa
A1  - Auvinen, Juha
A1  - Bartels, Meike
A1  - Beckmann, Jacques S.
A1  - Bilbao, Jose Ramon
A1  - Bond, Tom
A1  - Borja, Judith B.
A1  - Cavadino, Alana
A1  - Charoen, Pimphen
A1  - Chen, Zhanghua
A1  - Coin, Lachlan
A1  - Cooper, Cyrus
A1  - Curtin, John A.
A1  - Custovic, Adnan
A1  - Das, Shikta
A1  - Davies, Gareth E.
A1  - Dedoussis, George V.
A1  - Duijts, Liesbeth
A1  - Eastwood, Peter R.
A1  - Eliasen, Anders U.
A1  - Elliott, Paul
A1  - Eriksson, Johan G.
A1  - Estivill, Xavier
A1  - Fadista, Joao
A1  - Fedko, Iryna O.
A1  - Frayling, Timothy M.
A1  - Gaillard, Romy
A1  - Gauderman, W. James
A1  - Geller, Frank
A1  - Gilliland, Frank
A1  - Gilsanz, Vincente
A1  - Granell, Raquel
A1  - Grarup, Niels
A1  - Groop, Leif
A1  - Hadley, Dexter
A1  - Hakonarson, Hakon
A1  - Hansen, Torben
A1  - Hartman, Catharina A.
A1  - Hattersley, Andrew T.
A1  - Hayes, M. Geoffrey
A1  - Hebebrand, Johannes
A1  - Heinrich, Joachim
A1  - Helgeland, Oyvind
A1  - Henders, Anjali K.
A1  - Henderson, John
A1  - Henriksen, Tine B.
A1  - Hirschhorn, Joel N.
A1  - Hivert, Marie-France
A1  - Hocher, Berthold
A1  - Holloway, John W.
A1  - Holt, Patrick
A1  - Hottenga, Jouke-Jan
A1  - Hypponen, Elina
A1  - Iniguez, Carmen
A1  - Johansson, Stefan
A1  - Jugessur, Astanand
A1  - Kahonen, Mika
A1  - Kalkwarf, Heidi J.
A1  - Kaprio, Jaakko
A1  - Karhunen, Ville
A1  - Kemp, John P.
A1  - Kerkhof, Marjan
A1  - Koppelman, Gerard H.
A1  - Korner, Antje
A1  - Kotecha, Sailesh
A1  - Kreiner-Moller, Eskil
A1  - Kulohoma, Benard
A1  - Kumar, Ashish
A1  - Kutalik, Zoltan
A1  - Lahti, Jari
A1  - Lappe, Joan M.
A1  - Larsson, Henrik
A1  - Lehtimaki, Terho
A1  - Lewin, Alexandra M.
A1  - Li, Jin
A1  - Lichtenstein, Paul
A1  - Lindgren, Cecilia M.
A1  - Lindi, Virpi
A1  - Linneberg, Allan
A1  - Liu, Xueping
A1  - Liu, Jun
A1  - Lowe, William L.
A1  - Lundstrom, Sebastian
A1  - Lyytikainen, Leo-Pekka
A1  - Ma, Ronald C. W.
A1  - Mace, Aurelien
A1  - Magi, Reedik
A1  - Magnus, Per
A1  - Mamun, Abdullah A.
A1  - Mannikko, Minna
A1  - Martin, Nicholas G.
A1  - Mbarek, Hamdi
A1  - McCarthy, Nina S.
A1  - Medland, Sarah E.
A1  - Melbye, Mads
A1  - Melen, Erik
A1  - Mohlke, Karen L.
A1  - Monnereau, Claire
A1  - Morgen, Camilla S.
A1  - Morris, Andrew P.
A1  - Murray, Jeffrey C.
A1  - Myhre, Ronny
A1  - Najman, Jackob M.
A1  - Nivard, Michel G.
A1  - Nohr, Ellen A.
A1  - Nolte, Ilja M.
A1  - Ntalla, Ioanna
A1  - Oberfield, Sharon E.
A1  - Oken, Emily
A1  - Oldehinkel, Albertine J.
A1  - Pahkala, Katja
A1  - Palviainen, Teemu
A1  - Panoutsopoulou, Kalliope
A1  - Pedersen, Oluf
A1  - Pennell, Craig E.
A1  - Pershagen, Goran
A1  - Pitkanen, Niina
A1  - Plomin, Robert
A1  - Power, Christine
A1  - Prasad, Rashmi B.
A1  - Prokopenko, Inga
A1  - Pulkkinen, Lea
A1  - Raikkonen, Katri
A1  - Raitakari, Olli T.
A1  - Reynolds, Rebecca M.
A1  - Richmond, Rebecca C.
A1  - Rivadeneira, Fernando
A1  - Rodriguez, Alina
A1  - Rose, Richard J.
A1  - Salem, Rany
A1  - Santa-Marina, Loreto
A1  - Saw, Seang-Mei
A1  - Schnurr, Theresia M.
A1  - Scott, James G.
A1  - Selzam, Saskia
A1  - Shepherd, John A.
A1  - Simpson, Angela
A1  - Skotte, Line
A1  - Sleiman, Patrick M. A.
A1  - Snieder, Harold
A1  - Sorensen, Thorkild I. A.
A1  - Standl, Marie
A1  - Steegers, Eric A. P.
A1  - Strachan, David P.
A1  - Straker, Leon
A1  - Strandberg, Timo
A1  - Taylor, Michelle
A1  - Teo, Yik-Ying
A1  - Thiering, Elisabeth
A1  - Torrent, Maties
A1  - Tyrrell, Jessica
A1  - Uitterlinden, Andre G.
A1  - van Beijsterveldt, Toos
A1  - van der Most, Peter J.
A1  - van Duijn, Cornelia M.
A1  - Viikari, Jorma
A1  - Vilor-Tejedor, Natalia
A1  - Vogelezang, Suzanne
A1  - Vonk, Judith M.
A1  - Vrijkotte, Tanja G. M.
A1  - Vuoksimaa, Eero
A1  - Wang, Carol A.
A1  - Watkins, William J.
A1  - Wichmann, H-Erich
A1  - Willemsen, Gonneke
A1  - Williams, Gail M.
A1  - Wilson, James F.
A1  - Wray, Naomi R.
A1  - Xu, Shujing
A1  - Xu, Cheng-Jian
A1  - Yaghootkar, Hanieh
A1  - Yi, Lu
A1  - Zafarmand, Mohammad Hadi
A1  - Zeggini, Eleftheria
A1  - Zemel, Babette S.
A1  - Hinney, Anke
A1  - Lakka, Timo A.
A1  - Whitehouse, Andrew J. O.
A1  - Sunyer, Jordi
A1  - Widen, Elisabeth E.
A1  - Feenstra, Bjarke
A1  - Sebert, Sylvain
A1  - Jacobsson, Bo
A1  - Njolstad, Pal R.
A1  - Stoltenberg, Camilla
A1  - Smith, George Davey
A1  - Lawlor, Debbie A.
A1  - Paternoster, Lavinia
A1  - Timpson, Nicholas J.
A1  - Ong, Ken K.
A1  - Bisgaard, Hans
A1  - Bonnelykke, Klaus
A1  - Jaddoe, Vincent W. V.
A1  - Tiemeier, Henning
A1  - Jarvelin, Marjo-Riitta
A1  - Evans, David M.
A1  - Perry, John R. B.
A1  - Grant, Struan F. A.
A1  - Boomsma, Dorret I.
A1  - Freathy, Rachel M.
A1  - McCarthy, Mark I.
A1  - Felix, Janine F.
T1  - The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia
BT  - design, results and future prospects
JF  - European journal of epidemiology
N2  - The impact of many unfavorable childhood traits or diseases, such as low birth weight and mental disorders, is not limited to childhood and adolescence, as they are also associated with poor outcomes in adulthood, such as cardiovascular disease. Insight into the genetic etiology of childhood and adolescent traits and disorders may therefore provide new perspectives, not only on how to improve wellbeing during childhood, but also how to prevent later adverse outcomes. To achieve the sample sizes required for genetic research, the Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia were established. The majority of the participating cohorts are longitudinal population-based samples, but other cohorts with data on early childhood phenotypes are also involved. Cohorts often have a broad focus and collect(ed) data on various somatic and psychiatric traits as well as environmental factors. Genetic variants have been successfully identified for multiple traits, for example, birth weight, atopic dermatitis, childhood BMI, allergic sensitization, and pubertal growth. Furthermore, the results have shown that genetic factors also partly underlie the association with adult traits. As sample sizes are still increasing, it is expected that future analyses will identify additional variants. This, in combination with the development of innovative statistical methods, will provide detailed insight on the mechanisms underlying the transition from childhood to adult disorders. Both consortia welcome new collaborations. Policies and contact details are available from the corresponding authors of this manuscript and/or the consortium websites.
KW  - Genetics
KW  - Consortium
KW  - Childhood traits and disorders
KW  - Longitudinal
Y1  - 2019
U6  - https://doi.org/10.1007/s10654-019-00502-9
SN  - 0393-2990
SN  - 1573-7284
VL  - 34
IS  - 3
SP  - 279
EP  - 300
PB  - Springer
CY  - Dordrecht
ER  - 
TY  - JOUR
A1  - Acciari, V. A.
A1  - Aliu, E.
A1  - Araya, M.
A1  - Arlen, T.
A1  - Aune, T.
A1  - Beilicke, M.
A1  - Benbow, W.
A1  - Bradbury, S. M.
A1  - Buckley, J. H.
A1  - Bugaev, V.
A1  - Byrum, K.
A1  - Cannon, A.
A1  - Cesarini, A.
A1  - Ciupik, L.
A1  - Collins-Hughes, E.
A1  - Cui, W.
A1  - Dickherber, R.
A1  - Duke, C.
A1  - Falcone, A.
A1  - Finley, J. P.
A1  - Fortson, L.
A1  - Furniss, A.
A1  - Galante, N.
A1  - Gall, D.
A1  - Godambe, S.
A1  - Griffin, S.
A1  - Guenette, R.
A1  - Gyuk, G.
A1  - Hanna, D.
A1  - Holder, J.
A1  - Hughes, G.
A1  - Hui, C. M.
A1  - Humensky, T. B.
A1  - Imran, A.
A1  - Kaaret, P.
A1  - Kertzman, M.
A1  - Krawczynski, H.
A1  - Krennrich, F.
A1  - Madhavan, A. S.
A1  - Maier, G.
A1  - Majumdar, P.
A1  - McArthur, S.
A1  - Moriarty, P.
A1  - Ong, R. A.
A1  - Otte, A. N.
A1  - Pandel, D.
A1  - Park, N.
A1  - Perkins, J. S.
A1  - Pohl, Martin
A1  - Prokoph, H.
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Reyes, L. C.
A1  - Reynolds, P. T.
A1  - Roache, E.
A1  - Rose, H. J.
A1  - Saxon, D. B.
A1  - Sembroski, G. H.
A1  - Sentuerk, G. D.
A1  - Smith, A. W.
A1  - Tesic, G.
A1  - Theiling, M.
A1  - Thibadeau, S.
A1  - Varlotta, A.
A1  - Vincent, S.
A1  - Vivier, M.
A1  - Wakely, S. P.
A1  - Ward, J. E.
A1  - Weekes, T. C.
A1  - Weinstein, A.
A1  - Weisgarber, T.
A1  - Weng, S.
A1  - Williams, D. A.
A1  - Wood, M.
A1  - Zitzer, B.
T1  - Gamma-ray observations of the Be/Pulsar binary 1A 0535+262 during a Giant X-Ray outburst
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics
N2  - Giant X-ray outbursts, with luminosities of about 10(37) erg s(-1), are observed roughly every five years from the nearby Be/pulsar binary 1A 0535+262. In this article, we present observations of the source with VERITAS at very high energies (VHEs; E > 100 GeV) triggered by the X-ray outburst in 2009 December. The observations started shortly after the onset of the outburst and provided comprehensive coverage of the episode, as well as the 111 day binary orbit. No VHE emission is evident at any time. We also examined data from the contemporaneous observations of 1A 0535+262 with the Fermi/Large Area Telescope at high-energy photons (E > 0.1 GeV) and failed to detect the source at GeV energies. The X-ray continua measured with the Swift/X-Ray Telescope and the RXTE/PCA can be well described by the combination of blackbody and Comptonized emission from thermal electrons. Therefore, the gamma-ray and X-ray observations suggest the absence of a significant population of non-thermal particles in the system. This distinguishes 1A 0535+262 from those Be X-ray binaries (such as PSR B1259-63 and LS I +61 degrees 303) that have been detected at GeV-TeV energies. We discuss the implications of the results on theoretical models.
KW  - acceleration of particles
KW  - binaries: general
KW  - gamma rays: general
KW  - stars: individual (1A 0535+262)
Y1  - 2011
U6  - https://doi.org/10.1088/0004-637X/733/2/96
SN  - 0004-637X
VL  - 733
IS  - 2
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Barlow, S. M.
A1  - Greig, J. B.
A1  - Bridges, J. W.
A1  - Carere, A.
A1  - Carpy, A. J.
A1  - Galli, Corrado L.
A1  - Kleiner, J.
A1  - Knudsen, I.
A1  - Koeter, H. B.
A1  - Levy, L. S.
A1  - Madsen, C.
A1  - Mayer, S.
A1  - Narbonne, J. F.
A1  - Pfannkuch, F.
A1  - Prodanchuk, M. G.
A1  - Smith, Mason R.
A1  - Steinberg, Pablo
T1  - Hazard identification by methods of animal-based toxicology
Y1  - 2002
ER  - 
TY  - JOUR
A1  - Abeysekara, A. U.
A1  - Benbow, Wystan
A1  - Bird, Ralph
A1  - Brantseg, T.
A1  - Brose, Robert
A1  - Buchovecky, M.
A1  - Buckley, J. H.
A1  - Bugaev, V.
A1  - Connolly, M. P.
A1  - Cui, Wei
A1  - Daniel, M. K.
A1  - Falcone, A.
A1  - Feng, Qi
A1  - Finley, John P.
A1  - Fortson, L.
A1  - Furniss, Amy
A1  - Gillanders, Gerard H.
A1  - Gunawardhana, Isuru
A1  - Huetten, M.
A1  - Hanna, David
A1  - Hervet, O.
A1  - Holder, J.
A1  - Hughes, G.
A1  - Humensky, T. B.
A1  - Johnson, Caitlin A.
A1  - Kaaret, Philip
A1  - Kar, P.
A1  - Kertzman, M.
A1  - Krennrich, F.
A1  - Lang, M. J.
A1  - Lin, T. T. Y.
A1  - McArthur, S.
A1  - Moriarty, P.
A1  - Mukherjee, Reshmi
A1  - Ong, R. A.
A1  - Otte, Adam Nepomuk
A1  - Park, N.
A1  - Petrashyk, A.
A1  - Pohl, Martin
A1  - Pueschel, Elisa
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Reynolds, P. T.
A1  - Richards, Gregory T.
A1  - Roache, E.
A1  - Rulten, C.
A1  - Sadeh, I.
A1  - Santander, M.
A1  - Sembroski, G. H.
A1  - Shahinyan, Karlen
A1  - Wakely, S. P.
A1  - Weinstein, A.
A1  - Wells, R. M.
A1  - Wilcox, P.
A1  - Williams, D. A.
A1  - Zitzer, B.
A1  - Jorstad, Svetlana G.
A1  - Marscher, Alan P.
A1  - Lister, Matthew L.
A1  - Kovalev, Yuri Y.
A1  - Pushkarev, A. B.
A1  - Savolainen, Tuomas
A1  - Agudo, I.
A1  - Molina, S. N.
A1  - Gomez, J. L.
A1  - Larionov, Valeri M.
A1  - Borman, G. A.
A1  - Mokrushina, A. A.
A1  - Tornikoski, Merja
A1  - Lahteenmaki, A.
A1  - Chamani, W.
A1  - Enestam, S.
A1  - Kiehlmann, S.
A1  - Hovatta, Talvikki
A1  - Smith, P. S.
A1  - Pontrelli, P.
T1  - Multiwavelength Observations of the Blazar BL Lacertae
BT  - a new Fast TeV Gamma-Ray Flare
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics
N2  - Combined with measurements made by very-long-baseline interferometry, the observations of fast TeV gamma-ray flares probe the structure and emission mechanism of blazar jets. However, only a handful of such flares have been detected to date, and only within the last few years have these flares been observed from lower-frequency-peaked BL. Lac objects and flat-spectrum radio quasars. We report on a fast TeV gamma-ray flare from the blazar BL. Lacertae observed by the Very Energetic Radiation Imaging Telescope Array System (VERITAS). with a rise time of similar to 2.3 hr and a decay time of similar to 36 min. The peak flux above 200 GeV is (4.2 +/- 0.6) x 10(-6) photon m(-2) s(-1) measured with a 4-minute-binned light curve, corresponding to similar to 180% of the flux that is observed from the Crab Nebula above the same energy threshold. Variability contemporaneous with the TeV gamma-ray flare was observed in GeV gamma-ray, X-ray, and optical flux, as well as in optical and radio polarization. Additionally, a possible moving emission feature with superluminal apparent velocity was identified in Very Long Baseline Array observations at 43 GHz, potentially passing the radio core of the jet around the time of the gamma-ray flare. We discuss the constraints on the size, Lorentz factor, and location of the emitting region of the flare, and the interpretations with several theoretical models that invoke relativistic plasma passing stationary shocks.
KW  - BL Lacertae objects: individual (BL Lacertae = VER J2202+422)
KW  - galaxies: active
Y1  - 2018
U6  - https://doi.org/10.3847/1538-4357/aab35c
SN  - 0004-637X
SN  - 1538-4357
VL  - 856
IS  - 2
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Townsley, Leisa K.
A1  - Broos, Patrick S.
A1  - Corcoran, Michael F.
A1  - Feigelson, Eric D.
A1  - Gagne, Marc
A1  - Montmerle, Thierry
A1  - Oey, M. S.
A1  - Smith, Nathan
A1  - Garmire, Gordon P.
A1  - Getman, Konstantin V.
A1  - Povich, Matthew S.
A1  - Evans, Nancy Remage
A1  - Naze, Yael
A1  - Parkin, E. R.
A1  - Preibisch, Thomas
A1  - Wang, Junfeng
A1  - Wou, Scott J.
A1  - Chu, You-Hua
A1  - Cohen, David H.
A1  - Gruendl, Robert A.
A1  - Hamaguchi, Kenji
A1  - King, Robert R.
A1  - Mac Low, Mordecai-Mark
A1  - McCaughrean, Mark J.
A1  - Moffat, Anthony F. J.
A1  - Oskinova, Lida
A1  - Pittard, Julian M.
A1  - Stassun, Keivan G.
A1  - Ud-Doula, Asif
A1  - Walborn, Nolan R.
A1  - Waldron, Wayne L.
A1  - Churchwell, Ed
A1  - Nictiols, J. S.
A1  - Owocki, Stanley P.
A1  - Schulz, Norbert S.
T1  - An introduction to the chandra carina complex project
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics ; Supplement series
N2  - The Great Nebula in Carina provides an exceptional view into the violent massive star formation and feedback that typifies giant H II regions and starburst galaxies. We have mapped the Carina star-forming complex in X-rays, using archival Chandra data and a mosaic of 20 new 60 ks pointings using the Chandra X-ray Observatory's Advanced CCD Imaging Spectrometer, as a testbed for understanding recent and ongoing star formation and to probe Carina's regions of bright diffuse X-ray emission. This study has yielded a catalog of properties of > 14,000 X-ray point sources;> 9800 of them have multiwavelength counterparts. Using Chandra's unsurpassed X-ray spatial resolution, we have separated these point sources from the extensive, spatially-complex diffuse emission that pervades the region; X-ray properties of this diffuse emission suggest that it traces feedback from Carina's massive stars. In this introductory paper, we motivate the survey design, describe the Chandra observations, and present some simple results, providing a foundation for the 15 papers that follow in this special issue and that present detailed catalogs, methods, and science results.
KW  - H II regions
KW  - stars: massive
KW  - stars: pre-main sequence
KW  - X-rays: individual (Carina)
KW  - X-rays: ISM
KW  - X-rays: stars
Y1  - 2011
U6  - https://doi.org/10.1088/0067-0049/194/1/1
SN  - 0067-0049
VL  - 194
IS  - 1
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - van der Valk, Ralf J. P.
A1  - Kreiner-Moller, Eskil
A1  - Kooijman, Marjolein N.
A1  - Guxens, Monica
A1  - Stergiakouli, Evangelia
A1  - Saaf, Annika
A1  - Bradfield, Jonathan P.
A1  - Geller, Frank
A1  - Hayes, M. Geoffrey
A1  - Cousminer, Diana L.
A1  - Koerner, Antje
A1  - Thiering, Elisabeth
A1  - Curtin, John A.
A1  - Myhre, Ronny
A1  - Huikari, Ville
A1  - Joro, Raimo
A1  - Kerkhof, Marjan
A1  - Warrington, Nicole M.
A1  - Pitkanen, Niina
A1  - Ntalla, Ioanna
A1  - Horikoshi, Momoko
A1  - Veijola, Riitta
A1  - Freathy, Rachel M.
A1  - Teo, Yik-Ying
A1  - Barton, Sheila J.
A1  - Evans, David M.
A1  - Kemp, John P.
A1  - St Pourcain, Beate
A1  - Ring, Susan M.
A1  - Smith, George Davey
A1  - Bergstrom, Anna
A1  - Kull, Inger
A1  - Hakonarson, Hakon
A1  - Mentch, Frank D.
A1  - Bisgaard, Hans
A1  - Chawes, Bo Lund Krogsgaard
A1  - Stokholm, Jakob
A1  - Waage, Johannes
A1  - Eriksen, Patrick
A1  - Sevelsted, Astrid
A1  - Melbye, Mads
A1  - van Duijn, Cornelia M.
A1  - Medina-Gomez, Carolina
A1  - Hofman, Albert
A1  - de Jongste, Johan C.
A1  - Taal, H. Rob
A1  - Uitterlinden, Andre G.
A1  - Armstrong, Loren L.
A1  - Eriksson, Johan
A1  - Palotie, Aarno
A1  - Bustamante, Mariona
A1  - Estivill, Xavier
A1  - Gonzalez, Juan R.
A1  - Llop, Sabrina
A1  - Kiess, Wieland
A1  - Mahajan, Anubha
A1  - Flexeder, Claudia
A1  - Tiesler, Carla M. T.
A1  - Murray, Clare S.
A1  - Simpson, Angela
A1  - Magnus, Per
A1  - Sengpiel, Verena
A1  - Hartikainen, Anna-Liisa
A1  - Keinanen-Kiukaanniemi, Sirkka
A1  - Lewin, Alexandra
A1  - Alves, Alexessander Da Silva Couto
A1  - Blakemore, Alexandra I. F.
A1  - Buxton, Jessica L.
A1  - Kaakinen, Marika
A1  - Rodriguez, Alina
A1  - Sebert, Sylvain
A1  - Vaarasmaki, Marja
A1  - Lakka, Timo
A1  - Lindi, Virpi
A1  - Gehring, Ulrike
A1  - Postma, Dirkje S.
A1  - Ang, Wei
A1  - Newnham, John P.
A1  - Lyytikainen, Leo-Pekka
A1  - Pahkala, Katja
A1  - Raitakari, Olli T.
A1  - Panoutsopoulou, Kalliope
A1  - Zeggini, Eleftheria
A1  - Boomsma, Dorret I.
A1  - Groen-Blokhuis, Maria
A1  - Ilonen, Jorma
A1  - Franke, Lude
A1  - Hirschhorn, Joel N.
A1  - Pers, Tune H.
A1  - Liang, Liming
A1  - Huang, Jinyan
A1  - Hocher, Berthold
A1  - Knip, Mikael
A1  - Saw, Seang-Mei
A1  - Holloway, John W.
A1  - Melen, Erik
A1  - Grant, Struan F. A.
A1  - Feenstra, Bjarke
A1  - Lowe, William L.
A1  - Widen, Elisabeth
A1  - Sergeyev, Elena
A1  - Grallert, Harald
A1  - Custovic, Adnan
A1  - Jacobsson, Bo
A1  - Jarvelin, Marjo-Riitta
A1  - Atalay, Mustafa
A1  - Koppelman, Gerard H.
A1  - Pennell, Craig E.
A1  - Niinikoski, Harri
A1  - Dedoussis, George V.
A1  - Mccarthy, Mark I.
A1  - Frayling, Timothy M.
A1  - Sunyer, Jordi
A1  - Timpson, Nicholas J.
A1  - Rivadeneira, Fernando
A1  - Bonnelykke, Klaus
A1  - Jaddoe, Vincent W. V.
T1  - A novel common variant in DCST2 is associated with length in early life and height in adulthood
JF  - Human molecular genetics
N2  - Common genetic variants have been identified for adult height, but not much is known about the genetics of skeletal growth in early life. To identify common genetic variants that influence fetal skeletal growth, we meta-analyzed 22 genome-wide association studies (Stage 1; N = 28 459). We identified seven independent top single nucleotide polymorphisms (SNPs) (P < 1 x 10(-6)) for birth length, of which three were novel and four were in or near loci known to be associated with adult height (LCORL, PTCH1, GPR126 and HMGA2). The three novel SNPs were followed-up in nine replication studies (Stage 2; N = 11 995), with rs905938 in DC-STAMP domain containing 2 (DCST2) genome-wide significantly associated with birth length in a joint analysis (Stages 1 + 2; beta = 0.046, SE = 0.008, P = 2.46 x 10(-8), explained variance = 0.05%). Rs905938 was also associated with infant length (N = 28 228; P = 5.54 x 10(-4)) and adult height (N = 127 513; P = 1.45 x 10(-5)). DCST2 is a DC-STAMP-like protein family member and DC-STAMP is an osteoclast cell-fusion regulator. Polygenic scores based on 180 SNPs previously associated with human adult stature explained 0.13% of variance in birth length. The same SNPs explained 2.95% of the variance of infant length. Of the 180 known adult height loci, 11 were genome-wide significantly associated with infant length (SF3B4, LCORL, SPAG17, C6orf173, PTCH1, GDF5, ZNFX1, HHIP, ACAN, HLA locus and HMGA2). This study highlights that common variation in DCST2 influences variation in early growth and adult height.
Y1  - 2015
U6  - https://doi.org/10.1093/hmg/ddu510
SN  - 0964-6906
SN  - 1460-2083
VL  - 24
IS  - 4
SP  - 1155
EP  - 1168
PB  - Oxford Univ. Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Kikstra, Jarmo S.
A1  - Nicholls, Zebedee R. J.
A1  - Smith, Christopher J.
A1  - Lewis, Jared
A1  - Lamboll, Robin D.
A1  - Byers, Edward
A1  - Sandstad, Marit
A1  - Meinshausen, Malte
A1  - Gidden, Matthew J.
A1  - Rogelj, Joeri
A1  - Kriegler, Elmar
A1  - Peters, Glen P.
A1  - Fuglestvedt, Jan S.
A1  - Skeie, Ragnhild B.
A1  - Samset, Bjørn H.
A1  - Wienpahl, Laura
A1  - van Vuuren, Detlef P.
A1  - van der Wijst, Kaj-Ivar
A1  - Al Khourdajie, Alaa
A1  - Forster, Piers M.
A1  - Reisinger, Andy
A1  - Schaeffer, Roberto
A1  - Riahi, Keywan
T1  - The IPCC Sixth Assessment Report WGIII climate assessment of mitigation pathways
BT  - from emissions to global temperatures
JF  - Geoscientific model development
N2  - While the Intergovernmental Panel on Climate Change (IPCC) physical science reports usually assess a handful of future scenarios, the Working Group III contribution on climate mitigation to the IPCC's Sixth Assessment Report (AR6 WGIII) assesses hundreds to thousands of future emissions scenarios. A key task in WGIII is to assess the global mean temperature outcomes of these scenarios in a consistent manner, given the challenge that the emissions scenarios from different integrated assessment models (IAMs) come with different sectoral and gas-to-gas coverage and cannot all be assessed consistently by complex Earth system models. In this work, we describe the “climate-assessment” workflow and its methods, including infilling of missing emissions and emissions harmonisation as applied to 1202 mitigation scenarios in AR6 WGIII. We evaluate the global mean temperature projections and effective radiative forcing (ERF) characteristics of climate emulators FaIRv1.6.2 and MAGICCv7.5.3 and use the CICERO simple climate model (CICERO-SCM) for sensitivity analysis. We discuss the implied overshoot severity of the mitigation pathways using overshoot degree years and look at emissions and temperature characteristics of scenarios compatible with one possible interpretation of the Paris Agreement. We find that the lowest class of emissions scenarios that limit global warming to “1.5 ∘C (with a probability of greater than 50 %) with no or limited overshoot” includes 97 scenarios for MAGICCv7.5.3 and 203 for FaIRv1.6.2. For the MAGICCv7.5.3 results, “limited overshoot” typically implies exceedance of median temperature projections of up to about 0.1 ∘C for up to a few decades before returning to below 1.5 ∘C by or before the year 2100. For more than half of the scenarios in this category that comply with three criteria for being “Paris-compatible”, including net-zero or net-negative greenhouse gas (GHG) emissions, median temperatures decline by about 0.3–0.4 ∘C after peaking at 1.5–1.6 ∘C in 2035–2055. We compare the methods applied in AR6 with the methods used for SR1.5 and discuss their implications. This article also introduces a “climate-assessment” Python package which allows for fully reproducing the IPCC AR6 WGIII temperature assessment. This work provides a community tool for assessing the temperature outcomes of emissions pathways and provides a basis for further work such as extending the workflow to include downscaling of climate characteristics to a regional level and calculating impacts.
Y1  - 2022
U6  - https://doi.org/10.5194/gmd-15-9075-2022
SN  - 1991-959X
SN  - 1991-9603
VL  - 15
IS  - 24
SP  - 9075
EP  - 9109
PB  - Copernicus
CY  - Katlenburg-Lindau
ER  - 
TY  - JOUR
A1  - Seroussi, Helene
A1  - Nowicki, Sophie
A1  - Payne, Antony J.
A1  - Goelzer, Heiko
A1  - Lipscomb, William H.
A1  - Abe-Ouchi, Ayako
A1  - Agosta, Cecile
A1  - Albrecht, Torsten
A1  - Asay-Davis, Xylar
A1  - Barthel, Alice
A1  - Calov, Reinhard
A1  - Cullather, Richard
A1  - Dumas, Christophe
A1  - Galton-Fenzi, Benjamin K.
A1  - Gladstone, Rupert
A1  - Golledge, Nicholas R.
A1  - Gregory, Jonathan M.
A1  - Greve, Ralf
A1  - Hattermann, Tore
A1  - Hoffman, Matthew J.
A1  - Humbert, Angelika
A1  - Huybrechts, Philippe
A1  - Jourdain, Nicolas C.
A1  - Kleiner, Thomas
A1  - Larour, Eric
A1  - Leguy, Gunter R.
A1  - Lowry, Daniel P.
A1  - Little, Chistopher M.
A1  - Morlighem, Mathieu
A1  - Pattyn, Frank
A1  - Pelle, Tyler
A1  - Price, Stephen F.
A1  - Quiquet, Aurelien
A1  - Reese, Ronja
A1  - Schlegel, Nicole-Jeanne
A1  - Shepherd, Andrew
A1  - Simon, Erika
A1  - Smith, Robin S.
A1  - Straneo, Fiammetta
A1  - Sun, Sainan
A1  - Trusel, Luke D.
A1  - Van Breedam, Jonas
A1  - van de Wal, Roderik S. W.
A1  - Winkelmann, Ricarda
A1  - Zhao, Chen
A1  - Zhang, Tong
A1  - Zwinger, Thomas
T1  - ISMIP6 Antarctica
BT  - a multi-model ensemble of the Antarctic ice sheet evolution over the 21st century
JF  - The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union
N2  - Ice flow models of the Antarctic ice sheet are commonly used to simulate its future evolution in response to different climate scenarios and assess the mass loss that would contribute to future sea level rise. However, there is currently no consensus on estimates of the future mass balance of the ice sheet, primarily because of differences in the representation of physical processes, forcings employed and initial states of ice sheet models. This study presents results from ice flow model simulations from 13 international groups focusing on the evolution of the Antarctic ice sheet during the period 2015-2100 as part of the Ice Sheet Model Intercomparison for CMIP6 (ISMIP6). They are forced with outputs from a subset of models from the Coupled Model Intercomparison Project Phase 5 (CMIP5), representative of the spread in climate model results. Simulations of the Antarctic ice sheet contribution to sea level rise in response to increased warming during this period varies between 7:8 and 30.0 cm of sea level equivalent (SLE) under Representative Concentration Pathway (RCP) 8.5 scenario forcing. These numbers are relative to a control experiment with constant climate conditions and should therefore be added to the mass loss contribution under climate conditions similar to present-day conditions over the same period. The simulated evolution of the West Antarctic ice sheet varies widely among models, with an overall mass loss, up to 18.0 cm SLE, in response to changes in oceanic conditions. East Antarctica mass change varies between 6 :1 and 8.3 cm SLE in the simulations, with a significant increase in surface mass balance outweighing the increased ice discharge under most RCP 8.5 scenario forcings. The inclusion of ice shelf collapse, here assumed to be caused by large amounts of liquid water ponding at the surface of ice shelves, yields an additional simulated mass loss of 28mm compared to simulations without ice shelf collapse. The largest sources of uncertainty come from the climate forcing, the ocean-induced melt rates, the calibration of these melt rates based on oceanic conditions taken outside of ice shelf cavities and the ice sheet dynamic response to these oceanic changes. Results under RCP 2.6 scenario based on two CMIP5 climate models show an additional mass loss of 0 and 3 cm of SLE on average compared to simulations done under present-day conditions for the two CMIP5 forcings used and display limited mass gain in East Antarctica.
Y1  - 2020
U6  - https://doi.org/10.5194/tc-14-3033-2020
SN  - 1994-0416
SN  - 1994-0424
VL  - 14
IS  - 9
SP  - 3033
EP  - 3070
PB  - Copernicus
CY  - Göttingen
ER  - 
TY  - JOUR
A1  - D'Hondt, Steven
A1  - Spivack, Arthur J.
A1  - Pockalny, Robert
A1  - Ferdelman, Timothy G.
A1  - Fischer, Jan P.
A1  - Kallmeyer, Jens
A1  - Abrams, Lewis J.
A1  - Smith, David C.
A1  - Graham, Dennis
A1  - Hasiuk, Franciszek
A1  - Schrum, Heather
A1  - Stancin, Andrea M.
T1  - Subseafloor sedimentary life in the South Pacific Gyre
N2  - The low-productivity South Pacific Gyre (SPG) is Earth's largest oceanic province. Its sediment accumulates extraordinarily slowly (0.1-1 m per million years). This sediment contains a living community that is characterized by very low biomass and very low metabolic activity. At every depth in cored SPG sediment, mean cell abundances are 3 to 4 orders of magnitude lower than at the same depths in all previously explored subseafloor communities. The net rate of respiration by the subseafloor sedimentary community at each SPG site is 1 to 3 orders of magnitude lower than the rates at previously explored sites. Because of the low respiration rates and the thinness of the sediment, interstitial waters are oxic throughout the sediment column in most of this region. Consequently, the sedimentary community of the SPG is predominantly aerobic, unlike previously explored subseafloor communities. Generation of H-2 by radiolysis of water is a significant electron-donor source for this community. The per-cell respiration rates of this community are about 2 orders of magnitude higher (in oxidation/reduction equivalents) than in previously explored anaerobic subseafloor communities. Respiration rates and cell concentrations in subseafloor sediment throughout almost half of the world ocean may approach those in SPG sediment.
Y1  - 2009
UR  - http://www.pnas.org/
U6  - https://doi.org/10.1073/pnas.0811793106
SN  - 0027-8424
ER  - 
TY  - JOUR
A1  - Smith, Bryce A.
A1  - Barlow, Brad N.
A1  - Rosenthal, Benjamin
A1  - Hermes, J. J.
A1  - Schaffenroth, Veronika
T1  - Pulse Timing Discovery of a Three-day Companion to the Hot Subdwarf BPM 36430
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics
N2  - Hot subdwarf B stars are core-helium-burning objects that have undergone envelope stripping, likely by a binary companion. Using high-speed photometry from the Transiting Exoplanet Survey Satellite, we have discovered the hot subdwarf BPM 36430 is a hybrid sdBV(rs) pulsator exhibiting several low-amplitude g-modes and a strong p-mode pulsation. The latter shows a clear, periodic variation in its pulse arrival times. Fits to this phase oscillation imply BPM 36430 orbits a barycenter approximately 10 light-seconds away once every 3.1 days. Using the CHIRON echelle spectrograph on the CTIO 1.5 m telescope, we confirm the reflex motion by detecting a radial-velocity variation with semiamplitude, period, and phase in agreement with the pulse timings. We conclude that a white dwarf companion with minimum mass of approximate to 0.42 M (circle dot) orbits BPM 36430. Our study represents only the second time a companion orbiting a pulsating hot subdwarf or white dwarf has been detected from pulse timings and confirmed with radial velocities.
Y1  - 2022
U6  - https://doi.org/10.3847/1538-4357/ac9384
SN  - 0004-637X
SN  - 1538-4357
VL  - 939
IS  - 1
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Geist, Emily
A1  - Gallagher, John S.
A1  - Kotulla, Ralf
A1  - Oskinova, Lida
A1  - Hamann, Wolf-Rainer
A1  - Ramachandran, Varsha
A1  - Sabbi, Elena
A1  - Smith, Linda J.
A1  - Kniazev, Alexey
A1  - Nota, Antonella
A1  - Rickard, Matthew J.
T1  - Ionization and star formation in the giant H ii region SMC-N66
JF  - Publications of the Astronomical Society of the Pacific
N2  - The NGC 346 young stellar system and associated N66 giant H ii region in the Small Magellanic Cloud are the nearest example of a massive star-forming event in a low metallicity (Z approximate to 0.2Z (circle dot)) galaxy. With an age of less than or similar to 3 Myr this system provides a unique opportunity to study relationships between massive stars and their associated H ii region. Using archival data, we derive a total H alpha luminosity of L(H alpha) = 4.1 x 10(38) erg s(-1) corresponding to an H-photoionization rate of 3 x 10(50) s(-1). A comparison with a predicted stellar ionization rate derived from the more than 50 known O-stars in NGC 346, including massive stars recently classified from Hubble Space Telescope far-ultraviolet (FUV) spectra, indicates an approximate ionization balance. Spectra obtained with SALT suggest the ionization structure of N66 could be consistent with some leakage of ionizing photons. Due to the low metallicity, the FUV luminosity from NGC 346 is not confined to the interstellar cloud associated with N66. Ionization extends through much of the spatial extent of the N66 cloud complex, and most of the cloud mass is not ionized. The stellar mass estimated from nebular L(H alpha) appears to be lower than masses derived from the census of resolved stars which may indicate a disconnect between the formation of high and low mass stars in this region. We briefly discuss implications of the properties of N66 for studies of star formation and stellar feedback in low metallicity environments.
Y1  - 2022
U6  - https://doi.org/10.1088/1538-3873/ac697b
SN  - 0004-6280
SN  - 1538-3873
VL  - 134
IS  - 1036
PB  - IOP Publishing
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Crighton, Neil H. M.
A1  - Prochaska, J. Xavier
A1  - Murphy, Michael T.
A1  - Worseck, Gabor
A1  - Smith, Britton D.
T1  - Imprints of the first billion years
BT  - Lyman limit systems at z similar to 5
JF  - Monthly notices of the Royal Astronomical Society
N2  - Lyman limit systems (LLSs) trace the low-density circumgalactic medium and the most dense regions of the intergalactic medium, so their number density and evolution at high-redshift, just after reionization, are important to constrain. We present a survey for LLSs at high redshifts, z(LLS) = 3.5-5.4, in the homogeneous data set of 153 optical quasar spectra at z similar to 5 from the Giant Gemini GMOS survey. Our analysis includes detailed investigation of survey biases using mock spectra which provide important corrections to the raw measurements. We estimate the incidence of LLSs per unit redshift at z approximate to 4.4 to be l(z) = 2.6 +/- 0.4. Combining our results with previous surveys at z(LLS) < 4, the best-fit power-law evolution is l(z) = l(*)[(1 + z)/4](alpha) with l* = 1.46 +/- 0.11 and alpha = 1.70 +/- 0.22 (68 per cent confidence intervals). Despite hints in previous z(LLS) < 4 results, there is no indication for a deviation from this single power-law soon after reionization. Finally, we integrate our new results with previous surveys of the intergalactic and circumgalactic media to constrain the hydrogen column density distribution function, f(N-HI, X), over 10 orders ofmagnitude. The data at z similar to 5 are not well-described by the f(N-HI, X) model previously reported for z similar to 2-3 (after re-scaling) and a 7-pivot model fitting the full z similar to 2-5 data set is statistically unacceptable. We conclude that there is significant evolution in the shape of f(N-HI, X) over this similar to 2-billion-year period.
KW  - quasars: absorption lines
KW  - cosmological parameters
KW  - cosmology: observations
Y1  - 2019
U6  - https://doi.org/10.1093/mnras/sty2762
SN  - 0035-8711
SN  - 1365-2966
VL  - 482
IS  - 2
SP  - 1456
EP  - 1470
PB  - Oxford Univ. Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Eigmüller, Philipp
A1  - Chaushev, Alexander
A1  - Gillen, Edward
A1  - Smith, Alexis
A1  - Nielsen, Louise D.
A1  - Turner, Oliver
A1  - Csizmadia, Szilard
A1  - Smalley, Barry
A1  - Bayliss, Daniel
A1  - Belardi, Claudia
A1  - Bouchy, Francois
A1  - Burleigh, Matthew R.
A1  - Cabrera, Juan
A1  - Casewell, Sarah L.
A1  - Chazelas, Bruno
A1  - Cooke, Benjamin F.
A1  - Erikson, Anders
A1  - Gansicke, Boris T.
A1  - Guenther, Maximilian N.
A1  - Goad, Michael R.
A1  - Grange, Andrew
A1  - Jackman, James A. G.
A1  - Jenkins, James S.
A1  - McCormac, James
A1  - Moyano, Maximiliano
A1  - Pollacco, Don
A1  - Poppenhäger, Katja
A1  - Queloz, Didier
A1  - Raynard, Liam
A1  - Rauer, Heike
A1  - Udry, Stephane
A1  - Walker, Simon. R.
A1  - Watson, Christopher A.
A1  - West, Richard G.
A1  - Wheatley, Peter J.
T1  - NGTS-5b
BT  - a highly inflated planet offering insights into the sub-Jovian desert
JF  - Astronomy and astrophysics : an international weekly journal
N2  - Context. Planetary population analysis gives us insight into formation and evolution processes. For short-period planets, the sub-Jovian desert has been discussed in recent years with regard to the planet population in the mass/period and radius/period parameter space without taking stellar parameters into account. The Next Generation Transit Survey (NGTS) is optimised for detecting planets in this regime, which allows for further analysis of the sub-Jovian desert. Aims. With high-precision photometric surveys (e.g. with NGTS and TESS), which aim to detect short period planets especially around M/K-type host stars, stellar parameters need to be accounted for when empirical data are compared to model predictions. Presenting a newly discovered planet at the boundary of the sub-Jovian desert, we analyse its bulk properties and use it to show the properties of exoplanets that border the sub-Jovian desert. Methods. Using NGTS light curve and spectroscopic follow-up observations, we confirm the planetary nature of planet NGTS-5b and determine its mass. Using exoplanet archives, we set the planet in context with other discoveries. Results. NGTS-5b is a short-period planet with an orbital period of 3.3569866 +/- 0.0000026 days. With a mass of 0.229 +/- 0.037 M-Jup and a radius of 1.136 +/- 0.023 R-Jup, it is highly inflated. Its mass places it at the upper boundary of the sub-Jovian desert. Because the host is a K2 dwarf, we need to account for the stellar parameters when NGTS-5b is analysed with regard to planet populations. Conclusions. With red-sensitive surveys (e.g. with NGTS and TESS), we expect many more planets around late-type stars to be detected. An empirical analysis of the sub-Jovian desert should therefore take stellar parameters into account.
KW  - planets and satellites: detection
KW  - planets and satellites: gaseous planets
Y1  - 2019
U6  - https://doi.org/10.1051/0004-6361/201935206
SN  - 1432-0746
VL  - 625
PB  - EDP Sciences
CY  - Les Ulis
ER  - 
TY  - JOUR
A1  - Nuthmann, Antje
A1  - Smith, Tim J.
A1  - Engbert, Ralf
A1  - Henderson, John M.
T1  - CRISP: a computational model of fixation duration in scene viewing
N2  - Eye-movement control during scene viewing can be represented as a series of individual decisions about where and when to move the eyes. While substantial behavioral and computational research has been devoted to investigating the placement of fixations in scenes, relatively little is known about the mechanisms that control fixation durations. Here, we propose a computational model (CRISP) that accounts for saccade timing and programming and thus for variations in fixation durations in scene viewing. First, timing signals are modeled as continuous-time random walks. Second, difficulties at the level of visual and cognitive processing can inhibit and thus modulate saccade timing. Inhibition generates moment-by-moment changes in the random walk's transition rate and processing-related saccade cancellation. Third, saccade programming is completed in 2 stages: an initial, labile stage that is subject to cancellation and a subsequent, nonlabile stage. Several simulation studies tested the model's adequacy and generality. An initial simulation study explored the role of cognitive factors in scene viewing by examining how fixation durations differed under different viewing task instructions. Additional simulations investigated the degree to which fixation durations were under direct moment-to-moment control of the current visual scene. The present work further supports the conclusion that fixation durations, to a certain degree, reflect perceptual and cognitive activity in scene viewing. Computational model simulations contribute to an understanding of the underlying processes of gaze control.
Y1  - 2010
UR  - http://psycnet.apa.org/journals/rev/117/2/382/
ER  - 
TY  - JOUR
A1  - Macaruso, P.
A1  - Locke, J.
A1  - Smith, S. T.
A1  - Powers, Susan M.
T1  - Short-term Memory and phonological coding in develomental dyslexis
Y1  - 1996
ER  - 
TY  - JOUR
A1  - Krupnik, Seweryn
A1  - Wagner, Aleksandra
A1  - Vincent, Olga
A1  - Rudek, Tadeusz J.
A1  - Wade, Robert
A1  - Misik, Matúš
A1  - Akerboom, Sanne
A1  - Foulds, Chris
A1  - Smith Stegen, Karen
A1  - Adem, Çiğdem
A1  - Batel, Susana
A1  - Rabitz, Florian
A1  - Certomà, Chiara
A1  - Chodkowska-Miszczuk, Justyna
A1  - Dokupilová, Dušana
A1  - Leiren, Merethe D.
A1  - Ignatieva, Frolova M.
A1  - Gabaldón-Estevan, Daniel.
A1  - Horta, Ana
A1  - Karnøe, Peter
A1  - Lilliestam, Johan
A1  - Loorbach, Derk A.
A1  - Mühlemeier, Susan
A1  - Némoz, Sophie
A1  - Nilsson, Måns
A1  - Osička, Jan
A1  - Papamikrouli, Louiza
A1  - Pellizioni, Luigi
A1  - Sareen, Siddharth
A1  - Sarrica, Mauro
A1  - Seyfang, Gill
A1  - Sovacool, Benjamin K.
A1  - Telesiene, Audrone
A1  - Zapletalova, Veronika
A1  - von Wirth, Timo
T1  - Beyond technology
BT  - a research agenda for social sciences and humanities research on renewable energy in Europe
JF  - Energy research & social science
N2  - This article enriches the existing literature on the importance and role of the social sciences and humanities (SSH) in renewable energy sources research by providing a novel approach to instigating the future research agenda in this field. Employing a series of in-depth interviews, deliberative focus group workshops and a systematic horizon scanning process, which utilised the expert knowledge of 85 researchers from the field with diverse disciplinary backgrounds and expertise, the paper develops a set of 100 priority questions for future research within SSH scholarship on renewable energy sources. These questions were aggregated into four main directions: (i) deep transformations and connections to the broader economic system (i.e. radical ways of (re)arranging socio-technical, political and economic relations), (ii) cultural and geographical diversity (i.e. contextual cultural, historical, political and socio-economic factors influencing citizen support for energy transitions), (iii) complexifying energy governance (i.e. understanding energy systems from a systems dynamics perspective) and (iv) shifting from instrumental acceptance to value-based objectives (i.e. public support for energy transitions as a normative notion linked to trust-building and citizen engagement). While this agenda is not intended to be—and cannot be—exhaustive or exclusive, we argue that it advances the understanding of SSH research on renewable energy sources and may have important value in the prioritisation of SSH themes needed to enrich dialogues between policymakers, funding institutions and researchers. SSH scholarship should not be treated as instrumental to other research on renewable energy but as intrinsic and of the same hierarchical importance.
KW  - horizon scanning
KW  - research priorities
KW  - funding directions
KW  - EU Horizon Europe
KW  - research-policy interface
Y1  - 2022
U6  - https://doi.org/10.1016/j.erss.2022.102536
SN  - 22146296
VL  - 89
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Herrero, Mario
A1  - Thornton, Philip K.
A1  - Mason-D'Croz, Daniel
A1  - Palmer, Jeda
A1  - Bodirsky, Benjamin Leon
A1  - Pradhan, Prajal
A1  - Barrett, Christopher B.
A1  - Benton, Tim G.
A1  - Hall, Andrew
A1  - Pikaar, Ilje
A1  - Bogard, Jessica R.
A1  - Bonnett, Graham D.
A1  - Bryan, Brett A.
A1  - Campbell, Bruce M.
A1  - Christensen, Svend
A1  - Clark, Michael
A1  - Fanzo, Jessica
A1  - Godde, Cecile M.
A1  - Jarvis, Andy
A1  - Loboguerrero, Ana Maria
A1  - Mathys, Alexander
A1  - McIntyre, C. Lynne
A1  - Naylor, Rosamond L.
A1  - Nelson, Rebecca
A1  - Obersteiner, Michael
A1  - Parodi, Alejandro
A1  - Popp, Alexander
A1  - Ricketts, Katie
A1  - Smith, Pete
A1  - Valin, Hugo
A1  - Vermeulen, Sonja J.
A1  - Vervoort, Joost
A1  - van Wijk, Mark
A1  - van Zanten, Hannah H. E.
A1  - West, Paul C.
A1  - Wood, Stephen A.
A1  - Rockström, Johan
T1  - Articulating the effect of food systems innovation on the Sustainable Development Goals
JF  - The lancet Planetary health
N2  - Food system innovations will be instrumental to achieving multiple Sustainable Development Goals (SDGs). However, major innovation breakthroughs can trigger profound and disruptive changes, leading to simultaneous and interlinked reconfigurations of multiple parts of the global food system. The emergence of new technologies or social solutions, therefore, have very different impact profiles, with favourable consequences for some SDGs and unintended adverse side-effects for others. Stand-alone innovations seldom achieve positive outcomes over multiple sustainability dimensions. Instead, they should be embedded as part of systemic changes that facilitate the implementation of the SDGs. Emerging trade-offs need to be intentionally addressed to achieve true sustainability, particularly those involving social aspects like inequality in its many forms, social justice, and strong institutions, which remain challenging. Trade-offs with undesirable consequences are manageable through the development of well planned transition pathways, careful monitoring of key indicators, and through the implementation of transparent science targets at the local level.
Y1  - 2020
U6  - https://doi.org/10.1016/S2542-5196(20)30277-1
SN  - 2542-5196
VL  - 5
IS  - 1
SP  - E50
EP  - E62
PB  - Elsevier
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Marquer, Laurent
A1  - Gaillard, Marie-Jose
A1  - Sugita, Shinya
A1  - Poska, Anneli
A1  - Trondman, Anna-Kari
A1  - Mazier, Florence
A1  - Nielsen, Anne Birgitte
A1  - Fyfe, Ralph M.
A1  - Jonsson, Anna Maria
A1  - Smith, Benjamin
A1  - Kaplan, Jed O.
A1  - Alenius, Teija
A1  - Birks, H. John B.
A1  - Bjune, Anne E.
A1  - Christiansen, Jorg
A1  - Dodson, John
A1  - Edwards, Kevin J.
A1  - Giesecke, Thomas
A1  - Herzschuh, Ulrike
A1  - Kangur, Mihkel
A1  - Koff, Tiiu
A1  - Latalowa, Maligorzata
A1  - Lechterbeck, Jutta
A1  - Olofsson, Jorgen
A1  - Seppa, Heikki
T1  - Quantifying the effects of land use and climate on Holocene vegetation in Europe
JF  - Quaternary science reviews : the international multidisciplinary research and review journal
N2  - Early agriculture can be detected in palaeovegetation records, but quantification of the relative importance of climate and land use in influencing regional vegetation composition since the onset of agriculture is a topic that is rarely addressed. We present a novel approach that combines pollen-based REVEALS estimates of plant cover with climate, anthropogenic land-cover and dynamic vegetation modelling results. This is used to quantify the relative impacts of land use and climate on Holocene vegetation at a sub-continental scale, i.e. northern and western Europe north of the Alps. We use redundancy analysis and variation partitioning to quantify the percentage of variation in vegetation composition explained by the climate and land-use variables, and Monte Carlo permutation tests to assess the statistical significance of each variable. We further use a similarity index to combine pollen based REVEALS estimates with climate-driven dynamic vegetation modelling results. The overall results indicate that climate is the major driver of vegetation when the Holocene is considered as a whole and at the sub-continental scale, although land use is important regionally. Four critical phases of land-use effects on vegetation are identified. The first phase (from 7000 to 6500 BP) corresponds to the early impacts on vegetation of farming and Neolithic forest clearance and to the dominance of climate as a driver of vegetation change. During the second phase (from 4500 to 4000 BP), land use becomes a major control of vegetation. Climate is still the principal driver, although its influence decreases gradually. The third phase (from 2000 to 1500 BP) is characterised by the continued role of climate on vegetation as a consequence of late-Holocene climate shifts and specific climate events that influence vegetation as well as land use. The last phase (from 500 to 350 BP) shows an acceleration of vegetation changes, in particular during the last century, caused by new farming practices and forestry in response to population growth and industrialization. This is a unique signature of anthropogenic impact within the Holocene but European vegetation remains climatically sensitive and thus may continue to respond to ongoing climate change. (C) 2017 Elsevier Ltd. All rights reserved.
KW  - Climate
KW  - Holocene
KW  - Human impact
KW  - Land use
KW  - LPJ-GUESS
KW  - Europe
KW  - Pollen
KW  - REVEALS
KW  - Vegetation composition
Y1  - 2017
U6  - https://doi.org/10.1016/j.quascirev.2017.07.001
SN  - 0277-3791
VL  - 171
SP  - 20
EP  - 37
PB  - Elsevier
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Saikin, Anthony
A1  - Jordanova, Vania K.
A1  - Zhang, J. C.
A1  - Smith, C. W.
A1  - Spence, H. E.
A1  - Larsen, B. A.
A1  - Reeves, G. D.
A1  - Torbert, R. B.
A1  - Kletzing, C. A.
A1  - Zhelayskaya, I. S.
A1  - Shprits, Yuri Y.
T1  - Comparing simulated and observed EMIC wave amplitudes using in situ Van
JF  - Journal of Atmospheric and Solar-Terrestrial Physics
N2  - We perform a statistical study calculating electromagnetic ion cyclotron (EMIC) wave amplitudes based off in situ plasma measurements taken by the Van Allen Probes’ (1.1–5.8 Re) Helium, Oxygen, Proton, Electron (HOPE) instrument. Calculated wave amplitudes are compared to EMIC waves observed by the Electric and Magnetic Field Instrument Suite and Integrated Science on board the Van Allen Probes during the same period. The survey covers a 22-month period (1 November 2012 to 31 August 2014), a full Van Allen Probe magnetic local time (MLT) precession. The linear theory proxy was used to identify EMIC wave events with plasma conditions favorable for EMIC wave excitation. Two hundred and thirty-two EMIC wave events (103 H+-band and 129 He+-band) were selected for this comparison. Nearly all events selected are observed beyond L = 4. Results show that calculated wave amplitudes exclusively using the in situ HOPE measurements produce amplitudes too low compared to the observed EMIC wave amplitudes. Hot proton anisotropy (Ahp) distributions are asymmetric in MLT within the inner (L < 7) magnetosphere with peak (minimum) Ahp, ∼0.81 to 1.00 (∼0.62), observed in the dawn (dusk), 0000 < MLT ≤ 1200 (1200 < MLT ≤ 2400), sectors. Measurements of Ahp are found to decrease in the presence of EMIC wave activity. Ahp amplification factors are determined and vary with respect to EMIC wave-band and MLT. He+-band events generally require double (quadruple) the measured Ahp for the dawn (dusk) sector to reproduce the observed EMIC wave amplitudes.
KW  - EMIC waves
KW  - Van Allen Probes
KW  - Linear theory
KW  - Wave generation
Y1  - 2018
U6  - https://doi.org/10.1016/j.jastp.2018.01.024
SN  - 1364-6826
SN  - 1879-1824
VL  - 177
SP  - 190
EP  - 201
PB  - Elsevier
CY  - Oxford
ER  -