TY - JOUR A1 - Arnison, Paul G. A1 - Bibb, Mervyn J. A1 - Bierbaum, Gabriele A1 - Bowers, Albert A. A1 - Bugni, Tim S. A1 - Bulaj, Grzegorz A1 - Camarero, Julio A. A1 - Campopiano, Dominic J. A1 - Challis, Gregory L. A1 - Clardy, Jon A1 - Cotter, Paul D. A1 - Craik, David J. A1 - Dawson, Michael A1 - Dittmann-Thünemann, Elke A1 - Donadio, Stefano A1 - Dorrestein, Pieter C. A1 - Entian, Karl-Dieter A1 - Fischbach, Michael A. A1 - Garavelli, John S. A1 - Goeransson, Ulf A1 - Gruber, Christian W. A1 - Haft, Daniel H. A1 - Hemscheidt, Thomas K. A1 - Hertweck, Christian A1 - Hill, Colin A1 - Horswill, Alexander R. A1 - Jaspars, Marcel A1 - Kelly, Wendy L. A1 - Klinman, Judith P. A1 - Kuipers, Oscar P. A1 - Link, A. James A1 - Liu, Wen A1 - Marahiel, Mohamed A. A1 - Mitchell, Douglas A. A1 - Moll, Gert N. A1 - Moore, Bradley S. A1 - Mueller, Rolf A1 - Nair, Satish K. A1 - Nes, Ingolf F. A1 - Norris, Gillian E. A1 - Olivera, Baldomero M. A1 - Onaka, Hiroyasu A1 - Patchett, Mark L. A1 - Piel, Jörn A1 - Reaney, Martin J. T. A1 - Rebuffat, Sylvie A1 - Ross, R. Paul A1 - Sahl, Hans-Georg A1 - Schmidt, Eric W. A1 - Selsted, Michael E. A1 - Severinov, Konstantin A1 - Shen, Ben A1 - Sivonen, Kaarina A1 - Smith, Leif A1 - Stein, Torsten A1 - Suessmuth, Roderich D. A1 - Tagg, John R. A1 - Tang, Gong-Li A1 - Truman, Andrew W. A1 - Vederas, John C. A1 - Walsh, Christopher T. A1 - Walton, Jonathan D. A1 - Wenzel, Silke C. A1 - Willey, Joanne M. A1 - van der Donk, Wilfred A. T1 - Ribosomally synthesized and post-translationally modified peptide natural products overview and recommendations for a universal nomenclature JF - Natural product reports : a journal of current developments in bio-organic chemistry N2 - This review presents recommended nomenclature for the biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPPs), a rapidly growing class of natural products. The current knowledge regarding the biosynthesis of the >20 distinct compound classes is also reviewed, and commonalities are discussed. Y1 - 2013 U6 - https://doi.org/10.1039/c2np20085f SN - 0265-0568 VL - 30 IS - 1 SP - 108 EP - 160 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Townsley, Leisa K. A1 - Broos, Patrick S. A1 - Corcoran, Michael F. A1 - Feigelson, Eric D. A1 - Gagne, Marc A1 - Montmerle, Thierry A1 - Oey, M. S. A1 - Smith, Nathan A1 - Garmire, Gordon P. A1 - Getman, Konstantin V. A1 - Povich, Matthew S. A1 - Evans, Nancy Remage A1 - Naze, Yael A1 - Parkin, E. R. A1 - Preibisch, Thomas A1 - Wang, Junfeng A1 - Wou, Scott J. A1 - Chu, You-Hua A1 - Cohen, David H. A1 - Gruendl, Robert A. A1 - Hamaguchi, Kenji A1 - King, Robert R. A1 - Mac Low, Mordecai-Mark A1 - McCaughrean, Mark J. A1 - Moffat, Anthony F. J. A1 - Oskinova, Lida A1 - Pittard, Julian M. A1 - Stassun, Keivan G. A1 - Ud-Doula, Asif A1 - Walborn, Nolan R. A1 - Waldron, Wayne L. A1 - Churchwell, Ed A1 - Nictiols, J. S. A1 - Owocki, Stanley P. A1 - Schulz, Norbert S. T1 - An introduction to the chandra carina complex project JF - The astrophysical journal : an international review of spectroscopy and astronomical physics ; Supplement series N2 - The Great Nebula in Carina provides an exceptional view into the violent massive star formation and feedback that typifies giant H II regions and starburst galaxies. We have mapped the Carina star-forming complex in X-rays, using archival Chandra data and a mosaic of 20 new 60 ks pointings using the Chandra X-ray Observatory's Advanced CCD Imaging Spectrometer, as a testbed for understanding recent and ongoing star formation and to probe Carina's regions of bright diffuse X-ray emission. This study has yielded a catalog of properties of > 14,000 X-ray point sources;> 9800 of them have multiwavelength counterparts. Using Chandra's unsurpassed X-ray spatial resolution, we have separated these point sources from the extensive, spatially-complex diffuse emission that pervades the region; X-ray properties of this diffuse emission suggest that it traces feedback from Carina's massive stars. In this introductory paper, we motivate the survey design, describe the Chandra observations, and present some simple results, providing a foundation for the 15 papers that follow in this special issue and that present detailed catalogs, methods, and science results. KW - H II regions KW - stars: massive KW - stars: pre-main sequence KW - X-rays: individual (Carina) KW - X-rays: ISM KW - X-rays: stars Y1 - 2011 U6 - https://doi.org/10.1088/0067-0049/194/1/1 SN - 0067-0049 VL - 194 IS - 1 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - van der Valk, Ralf J. P. A1 - Kreiner-Moller, Eskil A1 - Kooijman, Marjolein N. A1 - Guxens, Monica A1 - Stergiakouli, Evangelia A1 - Saaf, Annika A1 - Bradfield, Jonathan P. A1 - Geller, Frank A1 - Hayes, M. Geoffrey A1 - Cousminer, Diana L. A1 - Koerner, Antje A1 - Thiering, Elisabeth A1 - Curtin, John A. A1 - Myhre, Ronny A1 - Huikari, Ville A1 - Joro, Raimo A1 - Kerkhof, Marjan A1 - Warrington, Nicole M. A1 - Pitkanen, Niina A1 - Ntalla, Ioanna A1 - Horikoshi, Momoko A1 - Veijola, Riitta A1 - Freathy, Rachel M. A1 - Teo, Yik-Ying A1 - Barton, Sheila J. A1 - Evans, David M. A1 - Kemp, John P. A1 - St Pourcain, Beate A1 - Ring, Susan M. A1 - Smith, George Davey A1 - Bergstrom, Anna A1 - Kull, Inger A1 - Hakonarson, Hakon A1 - Mentch, Frank D. A1 - Bisgaard, Hans A1 - Chawes, Bo Lund Krogsgaard A1 - Stokholm, Jakob A1 - Waage, Johannes A1 - Eriksen, Patrick A1 - Sevelsted, Astrid A1 - Melbye, Mads A1 - van Duijn, Cornelia M. A1 - Medina-Gomez, Carolina A1 - Hofman, Albert A1 - de Jongste, Johan C. A1 - Taal, H. Rob A1 - Uitterlinden, Andre G. A1 - Armstrong, Loren L. A1 - Eriksson, Johan A1 - Palotie, Aarno A1 - Bustamante, Mariona A1 - Estivill, Xavier A1 - Gonzalez, Juan R. A1 - Llop, Sabrina A1 - Kiess, Wieland A1 - Mahajan, Anubha A1 - Flexeder, Claudia A1 - Tiesler, Carla M. T. A1 - Murray, Clare S. A1 - Simpson, Angela A1 - Magnus, Per A1 - Sengpiel, Verena A1 - Hartikainen, Anna-Liisa A1 - Keinanen-Kiukaanniemi, Sirkka A1 - Lewin, Alexandra A1 - Alves, Alexessander Da Silva Couto A1 - Blakemore, Alexandra I. F. A1 - Buxton, Jessica L. A1 - Kaakinen, Marika A1 - Rodriguez, Alina A1 - Sebert, Sylvain A1 - Vaarasmaki, Marja A1 - Lakka, Timo A1 - Lindi, Virpi A1 - Gehring, Ulrike A1 - Postma, Dirkje S. A1 - Ang, Wei A1 - Newnham, John P. A1 - Lyytikainen, Leo-Pekka A1 - Pahkala, Katja A1 - Raitakari, Olli T. A1 - Panoutsopoulou, Kalliope A1 - Zeggini, Eleftheria A1 - Boomsma, Dorret I. A1 - Groen-Blokhuis, Maria A1 - Ilonen, Jorma A1 - Franke, Lude A1 - Hirschhorn, Joel N. A1 - Pers, Tune H. A1 - Liang, Liming A1 - Huang, Jinyan A1 - Hocher, Berthold A1 - Knip, Mikael A1 - Saw, Seang-Mei A1 - Holloway, John W. A1 - Melen, Erik A1 - Grant, Struan F. A. A1 - Feenstra, Bjarke A1 - Lowe, William L. A1 - Widen, Elisabeth A1 - Sergeyev, Elena A1 - Grallert, Harald A1 - Custovic, Adnan A1 - Jacobsson, Bo A1 - Jarvelin, Marjo-Riitta A1 - Atalay, Mustafa A1 - Koppelman, Gerard H. A1 - Pennell, Craig E. A1 - Niinikoski, Harri A1 - Dedoussis, George V. A1 - Mccarthy, Mark I. A1 - Frayling, Timothy M. A1 - Sunyer, Jordi A1 - Timpson, Nicholas J. A1 - Rivadeneira, Fernando A1 - Bonnelykke, Klaus A1 - Jaddoe, Vincent W. V. T1 - A novel common variant in DCST2 is associated with length in early life and height in adulthood JF - Human molecular genetics N2 - Common genetic variants have been identified for adult height, but not much is known about the genetics of skeletal growth in early life. To identify common genetic variants that influence fetal skeletal growth, we meta-analyzed 22 genome-wide association studies (Stage 1; N = 28 459). We identified seven independent top single nucleotide polymorphisms (SNPs) (P < 1 x 10(-6)) for birth length, of which three were novel and four were in or near loci known to be associated with adult height (LCORL, PTCH1, GPR126 and HMGA2). The three novel SNPs were followed-up in nine replication studies (Stage 2; N = 11 995), with rs905938 in DC-STAMP domain containing 2 (DCST2) genome-wide significantly associated with birth length in a joint analysis (Stages 1 + 2; beta = 0.046, SE = 0.008, P = 2.46 x 10(-8), explained variance = 0.05%). Rs905938 was also associated with infant length (N = 28 228; P = 5.54 x 10(-4)) and adult height (N = 127 513; P = 1.45 x 10(-5)). DCST2 is a DC-STAMP-like protein family member and DC-STAMP is an osteoclast cell-fusion regulator. Polygenic scores based on 180 SNPs previously associated with human adult stature explained 0.13% of variance in birth length. The same SNPs explained 2.95% of the variance of infant length. Of the 180 known adult height loci, 11 were genome-wide significantly associated with infant length (SF3B4, LCORL, SPAG17, C6orf173, PTCH1, GDF5, ZNFX1, HHIP, ACAN, HLA locus and HMGA2). This study highlights that common variation in DCST2 influences variation in early growth and adult height. Y1 - 2015 U6 - https://doi.org/10.1093/hmg/ddu510 SN - 0964-6906 SN - 1460-2083 VL - 24 IS - 4 SP - 1155 EP - 1168 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Kikstra, Jarmo S. A1 - Nicholls, Zebedee R. J. A1 - Smith, Christopher J. A1 - Lewis, Jared A1 - Lamboll, Robin D. A1 - Byers, Edward A1 - Sandstad, Marit A1 - Meinshausen, Malte A1 - Gidden, Matthew J. A1 - Rogelj, Joeri A1 - Kriegler, Elmar A1 - Peters, Glen P. A1 - Fuglestvedt, Jan S. A1 - Skeie, Ragnhild B. A1 - Samset, Bjørn H. A1 - Wienpahl, Laura A1 - van Vuuren, Detlef P. A1 - van der Wijst, Kaj-Ivar A1 - Al Khourdajie, Alaa A1 - Forster, Piers M. A1 - Reisinger, Andy A1 - Schaeffer, Roberto A1 - Riahi, Keywan T1 - The IPCC Sixth Assessment Report WGIII climate assessment of mitigation pathways BT - from emissions to global temperatures JF - Geoscientific model development N2 - While the Intergovernmental Panel on Climate Change (IPCC) physical science reports usually assess a handful of future scenarios, the Working Group III contribution on climate mitigation to the IPCC's Sixth Assessment Report (AR6 WGIII) assesses hundreds to thousands of future emissions scenarios. A key task in WGIII is to assess the global mean temperature outcomes of these scenarios in a consistent manner, given the challenge that the emissions scenarios from different integrated assessment models (IAMs) come with different sectoral and gas-to-gas coverage and cannot all be assessed consistently by complex Earth system models. In this work, we describe the “climate-assessment” workflow and its methods, including infilling of missing emissions and emissions harmonisation as applied to 1202 mitigation scenarios in AR6 WGIII. We evaluate the global mean temperature projections and effective radiative forcing (ERF) characteristics of climate emulators FaIRv1.6.2 and MAGICCv7.5.3 and use the CICERO simple climate model (CICERO-SCM) for sensitivity analysis. We discuss the implied overshoot severity of the mitigation pathways using overshoot degree years and look at emissions and temperature characteristics of scenarios compatible with one possible interpretation of the Paris Agreement. We find that the lowest class of emissions scenarios that limit global warming to “1.5 ∘C (with a probability of greater than 50 %) with no or limited overshoot” includes 97 scenarios for MAGICCv7.5.3 and 203 for FaIRv1.6.2. For the MAGICCv7.5.3 results, “limited overshoot” typically implies exceedance of median temperature projections of up to about 0.1 ∘C for up to a few decades before returning to below 1.5 ∘C by or before the year 2100. For more than half of the scenarios in this category that comply with three criteria for being “Paris-compatible”, including net-zero or net-negative greenhouse gas (GHG) emissions, median temperatures decline by about 0.3–0.4 ∘C after peaking at 1.5–1.6 ∘C in 2035–2055. We compare the methods applied in AR6 with the methods used for SR1.5 and discuss their implications. This article also introduces a “climate-assessment” Python package which allows for fully reproducing the IPCC AR6 WGIII temperature assessment. This work provides a community tool for assessing the temperature outcomes of emissions pathways and provides a basis for further work such as extending the workflow to include downscaling of climate characteristics to a regional level and calculating impacts. Y1 - 2022 U6 - https://doi.org/10.5194/gmd-15-9075-2022 SN - 1991-959X SN - 1991-9603 VL - 15 IS - 24 SP - 9075 EP - 9109 PB - Copernicus CY - Katlenburg-Lindau ER - TY - JOUR A1 - D'Hondt, Steven A1 - Spivack, Arthur J. A1 - Pockalny, Robert A1 - Ferdelman, Timothy G. A1 - Fischer, Jan P. A1 - Kallmeyer, Jens A1 - Abrams, Lewis J. A1 - Smith, David C. A1 - Graham, Dennis A1 - Hasiuk, Franciszek A1 - Schrum, Heather A1 - Stancin, Andrea M. T1 - Subseafloor sedimentary life in the South Pacific Gyre N2 - The low-productivity South Pacific Gyre (SPG) is Earth's largest oceanic province. Its sediment accumulates extraordinarily slowly (0.1-1 m per million years). This sediment contains a living community that is characterized by very low biomass and very low metabolic activity. At every depth in cored SPG sediment, mean cell abundances are 3 to 4 orders of magnitude lower than at the same depths in all previously explored subseafloor communities. The net rate of respiration by the subseafloor sedimentary community at each SPG site is 1 to 3 orders of magnitude lower than the rates at previously explored sites. Because of the low respiration rates and the thinness of the sediment, interstitial waters are oxic throughout the sediment column in most of this region. Consequently, the sedimentary community of the SPG is predominantly aerobic, unlike previously explored subseafloor communities. Generation of H-2 by radiolysis of water is a significant electron-donor source for this community. The per-cell respiration rates of this community are about 2 orders of magnitude higher (in oxidation/reduction equivalents) than in previously explored anaerobic subseafloor communities. Respiration rates and cell concentrations in subseafloor sediment throughout almost half of the world ocean may approach those in SPG sediment. Y1 - 2009 UR - http://www.pnas.org/ U6 - https://doi.org/10.1073/pnas.0811793106 SN - 0027-8424 ER - TY - JOUR A1 - Smith, Bryce A. A1 - Barlow, Brad N. A1 - Rosenthal, Benjamin A1 - Hermes, J. J. A1 - Schaffenroth, Veronika T1 - Pulse Timing Discovery of a Three-day Companion to the Hot Subdwarf BPM 36430 JF - The astrophysical journal : an international review of spectroscopy and astronomical physics N2 - Hot subdwarf B stars are core-helium-burning objects that have undergone envelope stripping, likely by a binary companion. Using high-speed photometry from the Transiting Exoplanet Survey Satellite, we have discovered the hot subdwarf BPM 36430 is a hybrid sdBV(rs) pulsator exhibiting several low-amplitude g-modes and a strong p-mode pulsation. The latter shows a clear, periodic variation in its pulse arrival times. Fits to this phase oscillation imply BPM 36430 orbits a barycenter approximately 10 light-seconds away once every 3.1 days. Using the CHIRON echelle spectrograph on the CTIO 1.5 m telescope, we confirm the reflex motion by detecting a radial-velocity variation with semiamplitude, period, and phase in agreement with the pulse timings. We conclude that a white dwarf companion with minimum mass of approximate to 0.42 M (circle dot) orbits BPM 36430. Our study represents only the second time a companion orbiting a pulsating hot subdwarf or white dwarf has been detected from pulse timings and confirmed with radial velocities. Y1 - 2022 U6 - https://doi.org/10.3847/1538-4357/ac9384 SN - 0004-637X SN - 1538-4357 VL - 939 IS - 1 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Geist, Emily A1 - Gallagher, John S. A1 - Kotulla, Ralf A1 - Oskinova, Lida A1 - Hamann, Wolf-Rainer A1 - Ramachandran, Varsha A1 - Sabbi, Elena A1 - Smith, Linda J. A1 - Kniazev, Alexey A1 - Nota, Antonella A1 - Rickard, Matthew J. T1 - Ionization and star formation in the giant H ii region SMC-N66 JF - Publications of the Astronomical Society of the Pacific N2 - The NGC 346 young stellar system and associated N66 giant H ii region in the Small Magellanic Cloud are the nearest example of a massive star-forming event in a low metallicity (Z approximate to 0.2Z (circle dot)) galaxy. With an age of less than or similar to 3 Myr this system provides a unique opportunity to study relationships between massive stars and their associated H ii region. Using archival data, we derive a total H alpha luminosity of L(H alpha) = 4.1 x 10(38) erg s(-1) corresponding to an H-photoionization rate of 3 x 10(50) s(-1). A comparison with a predicted stellar ionization rate derived from the more than 50 known O-stars in NGC 346, including massive stars recently classified from Hubble Space Telescope far-ultraviolet (FUV) spectra, indicates an approximate ionization balance. Spectra obtained with SALT suggest the ionization structure of N66 could be consistent with some leakage of ionizing photons. Due to the low metallicity, the FUV luminosity from NGC 346 is not confined to the interstellar cloud associated with N66. Ionization extends through much of the spatial extent of the N66 cloud complex, and most of the cloud mass is not ionized. The stellar mass estimated from nebular L(H alpha) appears to be lower than masses derived from the census of resolved stars which may indicate a disconnect between the formation of high and low mass stars in this region. We briefly discuss implications of the properties of N66 for studies of star formation and stellar feedback in low metallicity environments. Y1 - 2022 U6 - https://doi.org/10.1088/1538-3873/ac697b SN - 0004-6280 SN - 1538-3873 VL - 134 IS - 1036 PB - IOP Publishing CY - Bristol ER - TY - JOUR A1 - Seroussi, Helene A1 - Nowicki, Sophie A1 - Payne, Antony J. A1 - Goelzer, Heiko A1 - Lipscomb, William H. A1 - Abe-Ouchi, Ayako A1 - Agosta, Cecile A1 - Albrecht, Torsten A1 - Asay-Davis, Xylar A1 - Barthel, Alice A1 - Calov, Reinhard A1 - Cullather, Richard A1 - Dumas, Christophe A1 - Galton-Fenzi, Benjamin K. A1 - Gladstone, Rupert A1 - Golledge, Nicholas R. A1 - Gregory, Jonathan M. A1 - Greve, Ralf A1 - Hattermann, Tore A1 - Hoffman, Matthew J. A1 - Humbert, Angelika A1 - Huybrechts, Philippe A1 - Jourdain, Nicolas C. A1 - Kleiner, Thomas A1 - Larour, Eric A1 - Leguy, Gunter R. A1 - Lowry, Daniel P. A1 - Little, Chistopher M. A1 - Morlighem, Mathieu A1 - Pattyn, Frank A1 - Pelle, Tyler A1 - Price, Stephen F. A1 - Quiquet, Aurelien A1 - Reese, Ronja A1 - Schlegel, Nicole-Jeanne A1 - Shepherd, Andrew A1 - Simon, Erika A1 - Smith, Robin S. A1 - Straneo, Fiammetta A1 - Sun, Sainan A1 - Trusel, Luke D. A1 - Van Breedam, Jonas A1 - van de Wal, Roderik S. W. A1 - Winkelmann, Ricarda A1 - Zhao, Chen A1 - Zhang, Tong A1 - Zwinger, Thomas T1 - ISMIP6 Antarctica BT - a multi-model ensemble of the Antarctic ice sheet evolution over the 21st century JF - The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union N2 - Ice flow models of the Antarctic ice sheet are commonly used to simulate its future evolution in response to different climate scenarios and assess the mass loss that would contribute to future sea level rise. However, there is currently no consensus on estimates of the future mass balance of the ice sheet, primarily because of differences in the representation of physical processes, forcings employed and initial states of ice sheet models. This study presents results from ice flow model simulations from 13 international groups focusing on the evolution of the Antarctic ice sheet during the period 2015-2100 as part of the Ice Sheet Model Intercomparison for CMIP6 (ISMIP6). They are forced with outputs from a subset of models from the Coupled Model Intercomparison Project Phase 5 (CMIP5), representative of the spread in climate model results. Simulations of the Antarctic ice sheet contribution to sea level rise in response to increased warming during this period varies between 7:8 and 30.0 cm of sea level equivalent (SLE) under Representative Concentration Pathway (RCP) 8.5 scenario forcing. These numbers are relative to a control experiment with constant climate conditions and should therefore be added to the mass loss contribution under climate conditions similar to present-day conditions over the same period. The simulated evolution of the West Antarctic ice sheet varies widely among models, with an overall mass loss, up to 18.0 cm SLE, in response to changes in oceanic conditions. East Antarctica mass change varies between 6 :1 and 8.3 cm SLE in the simulations, with a significant increase in surface mass balance outweighing the increased ice discharge under most RCP 8.5 scenario forcings. The inclusion of ice shelf collapse, here assumed to be caused by large amounts of liquid water ponding at the surface of ice shelves, yields an additional simulated mass loss of 28mm compared to simulations without ice shelf collapse. The largest sources of uncertainty come from the climate forcing, the ocean-induced melt rates, the calibration of these melt rates based on oceanic conditions taken outside of ice shelf cavities and the ice sheet dynamic response to these oceanic changes. Results under RCP 2.6 scenario based on two CMIP5 climate models show an additional mass loss of 0 and 3 cm of SLE on average compared to simulations done under present-day conditions for the two CMIP5 forcings used and display limited mass gain in East Antarctica. Y1 - 2020 U6 - https://doi.org/10.5194/tc-14-3033-2020 SN - 1994-0416 SN - 1994-0424 VL - 14 IS - 9 SP - 3033 EP - 3070 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Crighton, Neil H. M. A1 - Prochaska, J. Xavier A1 - Murphy, Michael T. A1 - Worseck, Gabor A1 - Smith, Britton D. T1 - Imprints of the first billion years BT - Lyman limit systems at z similar to 5 JF - Monthly notices of the Royal Astronomical Society N2 - Lyman limit systems (LLSs) trace the low-density circumgalactic medium and the most dense regions of the intergalactic medium, so their number density and evolution at high-redshift, just after reionization, are important to constrain. We present a survey for LLSs at high redshifts, z(LLS) = 3.5-5.4, in the homogeneous data set of 153 optical quasar spectra at z similar to 5 from the Giant Gemini GMOS survey. Our analysis includes detailed investigation of survey biases using mock spectra which provide important corrections to the raw measurements. We estimate the incidence of LLSs per unit redshift at z approximate to 4.4 to be l(z) = 2.6 +/- 0.4. Combining our results with previous surveys at z(LLS) < 4, the best-fit power-law evolution is l(z) = l(*)[(1 + z)/4](alpha) with l* = 1.46 +/- 0.11 and alpha = 1.70 +/- 0.22 (68 per cent confidence intervals). Despite hints in previous z(LLS) < 4 results, there is no indication for a deviation from this single power-law soon after reionization. Finally, we integrate our new results with previous surveys of the intergalactic and circumgalactic media to constrain the hydrogen column density distribution function, f(N-HI, X), over 10 orders ofmagnitude. The data at z similar to 5 are not well-described by the f(N-HI, X) model previously reported for z similar to 2-3 (after re-scaling) and a 7-pivot model fitting the full z similar to 2-5 data set is statistically unacceptable. We conclude that there is significant evolution in the shape of f(N-HI, X) over this similar to 2-billion-year period. KW - quasars: absorption lines KW - cosmological parameters KW - cosmology: observations Y1 - 2019 U6 - https://doi.org/10.1093/mnras/sty2762 SN - 0035-8711 SN - 1365-2966 VL - 482 IS - 2 SP - 1456 EP - 1470 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Eigmüller, Philipp A1 - Chaushev, Alexander A1 - Gillen, Edward A1 - Smith, Alexis A1 - Nielsen, Louise D. A1 - Turner, Oliver A1 - Csizmadia, Szilard A1 - Smalley, Barry A1 - Bayliss, Daniel A1 - Belardi, Claudia A1 - Bouchy, Francois A1 - Burleigh, Matthew R. A1 - Cabrera, Juan A1 - Casewell, Sarah L. A1 - Chazelas, Bruno A1 - Cooke, Benjamin F. A1 - Erikson, Anders A1 - Gansicke, Boris T. A1 - Guenther, Maximilian N. A1 - Goad, Michael R. A1 - Grange, Andrew A1 - Jackman, James A. G. A1 - Jenkins, James S. A1 - McCormac, James A1 - Moyano, Maximiliano A1 - Pollacco, Don A1 - Poppenhäger, Katja A1 - Queloz, Didier A1 - Raynard, Liam A1 - Rauer, Heike A1 - Udry, Stephane A1 - Walker, Simon. R. A1 - Watson, Christopher A. A1 - West, Richard G. A1 - Wheatley, Peter J. T1 - NGTS-5b BT - a highly inflated planet offering insights into the sub-Jovian desert JF - Astronomy and astrophysics : an international weekly journal N2 - Context. Planetary population analysis gives us insight into formation and evolution processes. For short-period planets, the sub-Jovian desert has been discussed in recent years with regard to the planet population in the mass/period and radius/period parameter space without taking stellar parameters into account. The Next Generation Transit Survey (NGTS) is optimised for detecting planets in this regime, which allows for further analysis of the sub-Jovian desert. Aims. With high-precision photometric surveys (e.g. with NGTS and TESS), which aim to detect short period planets especially around M/K-type host stars, stellar parameters need to be accounted for when empirical data are compared to model predictions. Presenting a newly discovered planet at the boundary of the sub-Jovian desert, we analyse its bulk properties and use it to show the properties of exoplanets that border the sub-Jovian desert. Methods. Using NGTS light curve and spectroscopic follow-up observations, we confirm the planetary nature of planet NGTS-5b and determine its mass. Using exoplanet archives, we set the planet in context with other discoveries. Results. NGTS-5b is a short-period planet with an orbital period of 3.3569866 +/- 0.0000026 days. With a mass of 0.229 +/- 0.037 M-Jup and a radius of 1.136 +/- 0.023 R-Jup, it is highly inflated. Its mass places it at the upper boundary of the sub-Jovian desert. Because the host is a K2 dwarf, we need to account for the stellar parameters when NGTS-5b is analysed with regard to planet populations. Conclusions. With red-sensitive surveys (e.g. with NGTS and TESS), we expect many more planets around late-type stars to be detected. An empirical analysis of the sub-Jovian desert should therefore take stellar parameters into account. KW - planets and satellites: detection KW - planets and satellites: gaseous planets Y1 - 2019 U6 - https://doi.org/10.1051/0004-6361/201935206 SN - 1432-0746 VL - 625 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - Nuthmann, Antje A1 - Smith, Tim J. A1 - Engbert, Ralf A1 - Henderson, John M. T1 - CRISP: a computational model of fixation duration in scene viewing N2 - Eye-movement control during scene viewing can be represented as a series of individual decisions about where and when to move the eyes. While substantial behavioral and computational research has been devoted to investigating the placement of fixations in scenes, relatively little is known about the mechanisms that control fixation durations. Here, we propose a computational model (CRISP) that accounts for saccade timing and programming and thus for variations in fixation durations in scene viewing. First, timing signals are modeled as continuous-time random walks. Second, difficulties at the level of visual and cognitive processing can inhibit and thus modulate saccade timing. Inhibition generates moment-by-moment changes in the random walk's transition rate and processing-related saccade cancellation. Third, saccade programming is completed in 2 stages: an initial, labile stage that is subject to cancellation and a subsequent, nonlabile stage. Several simulation studies tested the model's adequacy and generality. An initial simulation study explored the role of cognitive factors in scene viewing by examining how fixation durations differed under different viewing task instructions. Additional simulations investigated the degree to which fixation durations were under direct moment-to-moment control of the current visual scene. The present work further supports the conclusion that fixation durations, to a certain degree, reflect perceptual and cognitive activity in scene viewing. Computational model simulations contribute to an understanding of the underlying processes of gaze control. Y1 - 2010 UR - http://psycnet.apa.org/journals/rev/117/2/382/ ER - TY - JOUR A1 - Macaruso, P. A1 - Locke, J. A1 - Smith, S. T. A1 - Powers, Susan M. T1 - Short-term Memory and phonological coding in develomental dyslexis Y1 - 1996 ER - TY - JOUR A1 - Borde, Ron A1 - Smith, Jordan J. A1 - Sutherland, Rachel A1 - Nathan, Nicole A1 - Lubans, David Revalds T1 - Methodological considerations and impact of school-based interventions on objectively measured physical activity in adolescents: a systematic review and meta-analysis JF - Obesity reviews : an official journal of the International Association for the Study of Obesity N2 - Objective: The aims of this systematic review and meta-analysis are (i) to determine the impact of school-based interventions on objectively measured physical activity among adolescents and (ii) to examine accelerometer methods and decision rule reporting in previous interventions. Methods: A systematic search was performed to identify randomized controlled trials targeting adolescents (age: >= 10 years), conducted in the school setting, and reporting objectively measured physical activity. Random effects meta-analyses were conducted to determine the pooled effects of previous interventions on total and moderate-to-vigorous physical activity. Potential moderators of intervention effects were also explored. Results: Thirteen articles met the inclusion criteria, and twelve were included in the meta-analysis. The pooled effects were small and non-significant for both total physical activity (standardized mean difference = 0.02 [95% confidence interval = -0.13 to 0.18]) and moderate-to-vigorous physical activity (standardized mean difference = 0.24 [95% confidence interval = -0.08 to 0.56]). Sample age and accelerometer compliance were significant moderators for total physical activity, with a younger sample and higher compliance associated with larger effects. Conclusion: Previous school-based physical activity interventions targeting adolescents have been largely unsuccessful, particularly for older adolescents. There is a need for more high-quality research using objective monitoring in this population. Future interventions should comply with best-practice recommendations regarding physical activity monitoring protocols. KW - Accelerometer KW - physical activity KW - school KW - youth Y1 - 2017 U6 - https://doi.org/10.1111/obr.12517 SN - 1467-7881 SN - 1467-789X VL - 18 SP - 476 EP - 490 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Krupnik, Seweryn A1 - Wagner, Aleksandra A1 - Vincent, Olga A1 - Rudek, Tadeusz J. A1 - Wade, Robert A1 - Misik, Matúš A1 - Akerboom, Sanne A1 - Foulds, Chris A1 - Smith Stegen, Karen A1 - Adem, Çiğdem A1 - Batel, Susana A1 - Rabitz, Florian A1 - Certomà, Chiara A1 - Chodkowska-Miszczuk, Justyna A1 - Dokupilová, Dušana A1 - Leiren, Merethe D. A1 - Ignatieva, Frolova M. A1 - Gabaldón-Estevan, Daniel. A1 - Horta, Ana A1 - Karnøe, Peter A1 - Lilliestam, Johan A1 - Loorbach, Derk A. A1 - Mühlemeier, Susan A1 - Némoz, Sophie A1 - Nilsson, Måns A1 - Osička, Jan A1 - Papamikrouli, Louiza A1 - Pellizioni, Luigi A1 - Sareen, Siddharth A1 - Sarrica, Mauro A1 - Seyfang, Gill A1 - Sovacool, Benjamin K. A1 - Telesiene, Audrone A1 - Zapletalova, Veronika A1 - von Wirth, Timo T1 - Beyond technology BT - a research agenda for social sciences and humanities research on renewable energy in Europe JF - Energy research & social science N2 - This article enriches the existing literature on the importance and role of the social sciences and humanities (SSH) in renewable energy sources research by providing a novel approach to instigating the future research agenda in this field. Employing a series of in-depth interviews, deliberative focus group workshops and a systematic horizon scanning process, which utilised the expert knowledge of 85 researchers from the field with diverse disciplinary backgrounds and expertise, the paper develops a set of 100 priority questions for future research within SSH scholarship on renewable energy sources. These questions were aggregated into four main directions: (i) deep transformations and connections to the broader economic system (i.e. radical ways of (re)arranging socio-technical, political and economic relations), (ii) cultural and geographical diversity (i.e. contextual cultural, historical, political and socio-economic factors influencing citizen support for energy transitions), (iii) complexifying energy governance (i.e. understanding energy systems from a systems dynamics perspective) and (iv) shifting from instrumental acceptance to value-based objectives (i.e. public support for energy transitions as a normative notion linked to trust-building and citizen engagement). While this agenda is not intended to be—and cannot be—exhaustive or exclusive, we argue that it advances the understanding of SSH research on renewable energy sources and may have important value in the prioritisation of SSH themes needed to enrich dialogues between policymakers, funding institutions and researchers. SSH scholarship should not be treated as instrumental to other research on renewable energy but as intrinsic and of the same hierarchical importance. KW - horizon scanning KW - research priorities KW - funding directions KW - EU Horizon Europe KW - research-policy interface Y1 - 2022 U6 - https://doi.org/10.1016/j.erss.2022.102536 SN - 22146296 VL - 89 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Herrero, Mario A1 - Thornton, Philip K. A1 - Mason-D'Croz, Daniel A1 - Palmer, Jeda A1 - Bodirsky, Benjamin Leon A1 - Pradhan, Prajal A1 - Barrett, Christopher B. A1 - Benton, Tim G. A1 - Hall, Andrew A1 - Pikaar, Ilje A1 - Bogard, Jessica R. A1 - Bonnett, Graham D. A1 - Bryan, Brett A. A1 - Campbell, Bruce M. A1 - Christensen, Svend A1 - Clark, Michael A1 - Fanzo, Jessica A1 - Godde, Cecile M. A1 - Jarvis, Andy A1 - Loboguerrero, Ana Maria A1 - Mathys, Alexander A1 - McIntyre, C. Lynne A1 - Naylor, Rosamond L. A1 - Nelson, Rebecca A1 - Obersteiner, Michael A1 - Parodi, Alejandro A1 - Popp, Alexander A1 - Ricketts, Katie A1 - Smith, Pete A1 - Valin, Hugo A1 - Vermeulen, Sonja J. A1 - Vervoort, Joost A1 - van Wijk, Mark A1 - van Zanten, Hannah H. E. A1 - West, Paul C. A1 - Wood, Stephen A. A1 - Rockström, Johan T1 - Articulating the effect of food systems innovation on the Sustainable Development Goals JF - The lancet Planetary health N2 - Food system innovations will be instrumental to achieving multiple Sustainable Development Goals (SDGs). However, major innovation breakthroughs can trigger profound and disruptive changes, leading to simultaneous and interlinked reconfigurations of multiple parts of the global food system. The emergence of new technologies or social solutions, therefore, have very different impact profiles, with favourable consequences for some SDGs and unintended adverse side-effects for others. Stand-alone innovations seldom achieve positive outcomes over multiple sustainability dimensions. Instead, they should be embedded as part of systemic changes that facilitate the implementation of the SDGs. Emerging trade-offs need to be intentionally addressed to achieve true sustainability, particularly those involving social aspects like inequality in its many forms, social justice, and strong institutions, which remain challenging. Trade-offs with undesirable consequences are manageable through the development of well planned transition pathways, careful monitoring of key indicators, and through the implementation of transparent science targets at the local level. Y1 - 2020 U6 - https://doi.org/10.1016/S2542-5196(20)30277-1 SN - 2542-5196 VL - 5 IS - 1 SP - E50 EP - E62 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Marquer, Laurent A1 - Gaillard, Marie-Jose A1 - Sugita, Shinya A1 - Poska, Anneli A1 - Trondman, Anna-Kari A1 - Mazier, Florence A1 - Nielsen, Anne Birgitte A1 - Fyfe, Ralph M. A1 - Jonsson, Anna Maria A1 - Smith, Benjamin A1 - Kaplan, Jed O. A1 - Alenius, Teija A1 - Birks, H. John B. A1 - Bjune, Anne E. A1 - Christiansen, Jorg A1 - Dodson, John A1 - Edwards, Kevin J. A1 - Giesecke, Thomas A1 - Herzschuh, Ulrike A1 - Kangur, Mihkel A1 - Koff, Tiiu A1 - Latalowa, Maligorzata A1 - Lechterbeck, Jutta A1 - Olofsson, Jorgen A1 - Seppa, Heikki T1 - Quantifying the effects of land use and climate on Holocene vegetation in Europe JF - Quaternary science reviews : the international multidisciplinary research and review journal N2 - Early agriculture can be detected in palaeovegetation records, but quantification of the relative importance of climate and land use in influencing regional vegetation composition since the onset of agriculture is a topic that is rarely addressed. We present a novel approach that combines pollen-based REVEALS estimates of plant cover with climate, anthropogenic land-cover and dynamic vegetation modelling results. This is used to quantify the relative impacts of land use and climate on Holocene vegetation at a sub-continental scale, i.e. northern and western Europe north of the Alps. We use redundancy analysis and variation partitioning to quantify the percentage of variation in vegetation composition explained by the climate and land-use variables, and Monte Carlo permutation tests to assess the statistical significance of each variable. We further use a similarity index to combine pollen based REVEALS estimates with climate-driven dynamic vegetation modelling results. The overall results indicate that climate is the major driver of vegetation when the Holocene is considered as a whole and at the sub-continental scale, although land use is important regionally. Four critical phases of land-use effects on vegetation are identified. The first phase (from 7000 to 6500 BP) corresponds to the early impacts on vegetation of farming and Neolithic forest clearance and to the dominance of climate as a driver of vegetation change. During the second phase (from 4500 to 4000 BP), land use becomes a major control of vegetation. Climate is still the principal driver, although its influence decreases gradually. The third phase (from 2000 to 1500 BP) is characterised by the continued role of climate on vegetation as a consequence of late-Holocene climate shifts and specific climate events that influence vegetation as well as land use. The last phase (from 500 to 350 BP) shows an acceleration of vegetation changes, in particular during the last century, caused by new farming practices and forestry in response to population growth and industrialization. This is a unique signature of anthropogenic impact within the Holocene but European vegetation remains climatically sensitive and thus may continue to respond to ongoing climate change. (C) 2017 Elsevier Ltd. All rights reserved. KW - Climate KW - Holocene KW - Human impact KW - Land use KW - LPJ-GUESS KW - Europe KW - Pollen KW - REVEALS KW - Vegetation composition Y1 - 2017 U6 - https://doi.org/10.1016/j.quascirev.2017.07.001 SN - 0277-3791 VL - 171 SP - 20 EP - 37 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Saikin, Anthony A1 - Jordanova, Vania K. A1 - Zhang, J. C. A1 - Smith, C. W. A1 - Spence, H. E. A1 - Larsen, B. A. A1 - Reeves, G. D. A1 - Torbert, R. B. A1 - Kletzing, C. A. A1 - Zhelayskaya, I. S. A1 - Shprits, Yuri Y. T1 - Comparing simulated and observed EMIC wave amplitudes using in situ Van JF - Journal of Atmospheric and Solar-Terrestrial Physics N2 - We perform a statistical study calculating electromagnetic ion cyclotron (EMIC) wave amplitudes based off in situ plasma measurements taken by the Van Allen Probes’ (1.1–5.8 Re) Helium, Oxygen, Proton, Electron (HOPE) instrument. Calculated wave amplitudes are compared to EMIC waves observed by the Electric and Magnetic Field Instrument Suite and Integrated Science on board the Van Allen Probes during the same period. The survey covers a 22-month period (1 November 2012 to 31 August 2014), a full Van Allen Probe magnetic local time (MLT) precession. The linear theory proxy was used to identify EMIC wave events with plasma conditions favorable for EMIC wave excitation. Two hundred and thirty-two EMIC wave events (103 H+-band and 129 He+-band) were selected for this comparison. Nearly all events selected are observed beyond L = 4. Results show that calculated wave amplitudes exclusively using the in situ HOPE measurements produce amplitudes too low compared to the observed EMIC wave amplitudes. Hot proton anisotropy (Ahp) distributions are asymmetric in MLT within the inner (L < 7) magnetosphere with peak (minimum) Ahp, ∼0.81 to 1.00 (∼0.62), observed in the dawn (dusk), 0000 < MLT ≤ 1200 (1200 < MLT ≤ 2400), sectors. Measurements of Ahp are found to decrease in the presence of EMIC wave activity. Ahp amplification factors are determined and vary with respect to EMIC wave-band and MLT. He+-band events generally require double (quadruple) the measured Ahp for the dawn (dusk) sector to reproduce the observed EMIC wave amplitudes. KW - EMIC waves KW - Van Allen Probes KW - Linear theory KW - Wave generation Y1 - 2018 U6 - https://doi.org/10.1016/j.jastp.2018.01.024 SN - 1364-6826 SN - 1879-1824 VL - 177 SP - 190 EP - 201 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Kothari, Kritika A1 - Battisti, Rafael A1 - Boote, Kenneth J. A1 - Archontoulis, Sotirios A1 - Confalone, Adriana A1 - Constantin, Julie A1 - Cuadra, Santiago A1 - Debaeke, Philippe A1 - Faye, Babacar A1 - Grant, Brian A1 - Hoogenboom, Gerrit A1 - Jing, Qi A1 - van der Laan, Michael A1 - Macena da Silva, Fernando Antonio A1 - Marin, Fabio R. A1 - Nehbandani, Alireza A1 - Nendel, Claas A1 - Purcell, Larry C. A1 - Qian, Budong A1 - Ruane, Alex C. A1 - Schoving, Celine A1 - Silva, Evandro H. F. M. A1 - Smith, Ward A1 - Soltani, Afshin A1 - Srivastava, Amit A1 - Vieira, Nilson A. A1 - Slone, Stacey A1 - Salmeron, Montserrat T1 - Are soybean models ready for climate change food impact assessments? JF - European journal of agronomy : the official journal of the European Society for Agronomy N2 - An accurate estimation of crop yield under climate change scenarios is essential to quantify our ability to feed a growing population and develop agronomic adaptations to meet future food demand. A coordinated evaluation of yield simulations from process-based eco-physiological models for climate change impact assessment is still missing for soybean, the most widely grown grain legume and the main source of protein in our food chain. In this first soybean multi-model study, we used ten prominent models capable of simulating soybean yield under varying temperature and atmospheric CO2 concentration [CO2] to quantify the uncertainty in soybean yield simulations in response to these factors. Models were first parametrized with high quality measured data from five contrasting environments. We found considerable variability among models in simulated yield responses to increasing temperature and [CO2]. For example, under a + 3 degrees C temperature rise in our coolest location in Argentina, some models simulated that yield would reduce as much as 24%, while others simulated yield increases up to 29%. In our warmest location in Brazil, the models simulated a yield reduction ranging from a 38% decrease under + 3 degrees C temperature rise to no effect on yield. Similarly, when increasing [CO2] from 360 to 540 ppm, the models simulated a yield increase that ranged from 6% to 31%. Model calibration did not reduce variability across models but had an unexpected effect on modifying yield responses to temperature for some of the models. The high uncertainty in model responses indicates the limited applicability of individual models for climate change food projections. However, the ensemble mean of simulations across models was an effective tool to reduce the high uncertainty in soybean yield simulations associated with individual models and their parametrization. Ensemble mean yield responses to temperature and [CO2] were similar to those reported from the literature. Our study is the first demonstration of the benefits achieved from using an ensemble of grain legume models for climate change food projections, and highlights that further soybean model development with experiments under elevated [CO2] and temperature is needed to reduce the uncertainty from the individual models. KW - Agricultural Model Inter-comparison and Improvement Project (AgMIP); KW - Model ensemble KW - Model calibration KW - Temperature KW - Atmospheric CO2 KW - concentration KW - Legume model Y1 - 2022 U6 - https://doi.org/10.1016/j.eja.2022.126482 SN - 1161-0301 SN - 1873-7331 VL - 135 PB - Elsevier CY - Amsterdam ER -