TY - JOUR A1 - Abdo, A. A. A1 - Ackermann, Margit A1 - Ajello, M. A1 - Allafort, A. J. A1 - Baldini, L. A1 - Ballet, J. A1 - Barbiellini, G. A1 - Baring, M. G. A1 - Bastieri, D. A1 - Bechtol, K. C. A1 - Bellazzini, R. A1 - Berenji, B. A1 - Blandford, R. D. A1 - Bloom, E. D. A1 - Bonamente, E. A1 - Borgland, A. W. A1 - Bouvier, A. A1 - Brandt, T. J. A1 - Bregeon, Johan A1 - Brez, A. A1 - Brigida, M. A1 - Bruel, P. A1 - Buehler, R. A1 - Buson, S. A1 - Caliandro, G. A. A1 - Cameron, R. A. A1 - Cannon, A. A1 - Caraveo, P. A. A1 - Carrigan, Svenja A1 - Casandjian, J. M. A1 - Cavazzuti, E. A1 - Cecchi, C. A1 - Celik, O. A1 - Charles, E. A1 - Chekhtman, A. A1 - Cheung, C. C. A1 - Chiang, J. A1 - Ciprini, S. A1 - Claus, R. A1 - Cohen-Tanugi, J. A1 - Conrad, Jan A1 - Cutini, S. A1 - Dermer, C. D. A1 - de Palma, F. A1 - do Couto e Silva, E. A1 - Drell, P. S. A1 - Dubois, R. A1 - Dumora, D. A1 - Favuzzi, C. A1 - Fegan, S. J. A1 - Ferrara, E. C. A1 - Focke, W. B. A1 - Fortin, P. A1 - Frailis, M. A1 - Fuhrmann, L. A1 - Fukazawa, Y. A1 - Funk, S. A1 - Fusco, P. A1 - Gargano, F. A1 - Gasparrini, D. A1 - Gehrels, N. A1 - Germani, S. A1 - Giglietto, N. A1 - Giordano, F. A1 - Giroletti, M. A1 - Glanzman, T. A1 - Godfrey, G. A1 - Grenier, I. A. A1 - Guillemot, L. A1 - Guiriec, S. A1 - Hayashida, M. A1 - Hays, E. A1 - Horan, D. A1 - Hughes, R. E. A1 - Johannesson, G. A1 - Johnson, A. S. A1 - Johnson, W. N. A1 - Kadler, M. A1 - Kamae, T. A1 - Katagiri, H. A1 - Kataoka, J. A1 - Knoedlseder, J. A1 - Kuss, M. A1 - Lande, J. A1 - Latronico, L. A1 - Lee, S. -H. A1 - Lemoine-Goumard, M. A1 - Longo, F. A1 - Loparco, F. A1 - Lott, B. A1 - Lovellette, M. N. A1 - Lubrano, P. A1 - Madejski, G. M. A1 - Makeev, A. A1 - Max-Moerbeck, W. A1 - Mazziotta, Mario Nicola A1 - McEnery, J. E. A1 - Mehault, J. A1 - Michelson, P. F. A1 - Mitthumsiri, W. A1 - Mizuno, T. A1 - Moiseev, A. A. A1 - Monte, C. A1 - Monzani, M. E. A1 - Morselli, A. A1 - Moskalenko, I. V. A1 - Murgia, S. A1 - Naumann-Godo, M. A1 - Nishino, S. A1 - Nolan, P. L. A1 - Norris, J. P. A1 - Nuss, E. A1 - Ohsugi, T. A1 - Okumura, A. A1 - Omodei, N. A1 - Orlando, E. A1 - Ormes, J. F. A1 - Paneque, D. A1 - Panetta, J. H. A1 - Parent, D. A1 - Pavlidou, V. A1 - Pearson, T. J. A1 - Pelassa, V. A1 - Pepe, M. A1 - Pesce-Rollins, M. A1 - Piron, F. A1 - Porter, T. A. A1 - Raino, S. A1 - Rando, R. A1 - Razzano, M. A1 - Readhead, A. A1 - Reimer, A. A1 - Reimer, O. A1 - Richards, J. L. A1 - Ripken, J. A1 - Ritz, S. A1 - Roth, M. A1 - Sadrozinski, H. F. -W. A1 - Sanchez, D. A1 - Sander, A. A1 - Scargle, J. D. A1 - Sgro, C. A1 - Siskind, E. J. A1 - Smith, P. D. A1 - Spandre, G. A1 - Spinelli, P. A1 - Stawarz, L. A1 - Stevenson, M. A1 - Strickman, M. S. A1 - Sokolovsky, K. V. A1 - Suson, D. J. A1 - Takahashi, H. A1 - Takahashi, T. A1 - Tanaka, T. A1 - Thayer, J. B. A1 - Thayer, J. G. A1 - Thompson, D. J. A1 - Tibaldo, L. A1 - Torres, F. A1 - Tosti, G. A1 - Tramacere, A. A1 - Uchiyama, Y. A1 - Usher, T. L. A1 - Vandenbroucke, J. A1 - Vasileiou, V. A1 - Vilchez, N. A1 - Vitale, V. A1 - Waite, A. P. A1 - Wang, P. A1 - Wehrle, A. E. A1 - Winer, B. L. A1 - Wood, K. S. A1 - Yang, Z. A1 - Ylinen, T. A1 - Zensus, J. A. A1 - Ziegler, M. A1 - Aleksic, J. A1 - Antonelli, L. A. A1 - Antoranz, P. A1 - Backes, Michael A1 - Barrio, J. A. A1 - Gonzalez, J. Becerra A1 - Bednarek, W. A1 - Berdyugin, A. A1 - Berger, K. A1 - Bernardini, E. A1 - Biland, A. A1 - Blanch Bigas, O. A1 - Bock, R. K. A1 - Boller, A. A1 - Bonnoli, G. A1 - Bordas, Pol A1 - Tridon, D. Borla A1 - Bosch-Ramon, Valentin A1 - Bose, D. A1 - Braun, I. A1 - Bretz, T. A1 - Camara, M. A1 - Carmona, E. A1 - Carosi, A. A1 - Colin, P. A1 - Colombo, E. A1 - Contreras, J. L. A1 - Cortina, J. A1 - Covino, S. A1 - Dazzi, F. A1 - de Angelis, A. A1 - del Pozo, E. De Cea A1 - De Lotto, B. A1 - De Maria, M. A1 - De Sabata, F. A1 - Mendez, C. Delgado A1 - Ortega, A. Diago A1 - Doert, M. A1 - Dominguez, A. A1 - Prester, Dijana Dominis A1 - Dorner, D. A1 - Doro, M. A1 - Elsaesser, D. A1 - Ferenc, D. A1 - Fonseca, M. V. A1 - Font, L. A1 - Lopen, R. J. Garcia A1 - Garczarczyk, M. A1 - Gaug, M. A1 - Giavitto, G. A1 - Godinovi, N. A1 - Hadasch, D. A1 - Herrero, A. A1 - Hildebrand, D. A1 - Hoehne-Moench, D. A1 - Hose, J. A1 - Hrupec, D. A1 - Jogler, T. A1 - Klepser, S. A1 - Kraehenbuehl, T. A1 - Kranich, D. A1 - Krause, J. A1 - La Barbera, A. A1 - Leonardo, E. A1 - Lindfors, E. A1 - Lombardi, S. A1 - Lopez, M. A1 - Lorenz, E. A1 - Majumdar, P. A1 - Makariev, E. A1 - Maneva, G. A1 - Mankuzhiyil, N. A1 - Mannheim, K. A1 - Maraschi, L. A1 - Mariotti, M. A1 - Martinez, M. A1 - Mazin, D. A1 - Meucci, M. A1 - Miranda, J. M. A1 - Mirzoyan, R. A1 - Miyamoto, H. A1 - Moldon, J. A1 - Moralejo, A. A1 - Nieto, D. A1 - Nilsson, K. A1 - Orito, R. A1 - Oya, I. A1 - Paoletti, R. A1 - Paredes, J. M. A1 - Partini, S. A1 - Pasanen, M. A1 - Pauss, F. A1 - Pegna, R. G. A1 - Perez-Torres, M. A. A1 - Persic, M. A1 - Peruzzo, J. A1 - Pochon, J. A1 - Moroni, P. G. Prada A1 - Prada, F. A1 - Prandini, E. A1 - Puchades, N. A1 - Puljak, I. A1 - Reichardt, T. A1 - Reinthal, R. A1 - Rhode, W. A1 - Ribo, M. A1 - Rico, J. A1 - Rissi, M. A1 - Ruegamer, S. A1 - Saggion, A. A1 - Saito, K. A1 - Saito, T. Y. A1 - Salvati, M. A1 - Sanchez-Conde, M. A1 - Satalecka, K. A1 - Scalzotto, V. A1 - Scapin, V. A1 - Schultz, C. A1 - Schweizer, T. A1 - Shayduk, M. A1 - Shore, S. N. A1 - Sierpowska-Bartosik, A. A1 - Sillanpaa, A. A1 - Sitarek, J. A1 - Sobczynska, D. A1 - Spanier, F. A1 - Spiro, S. A1 - Stamerra, A. A1 - Steinke, B. A1 - Storz, J. A1 - Strah, N. A1 - Struebig, J. C. A1 - Suric, T. A1 - Takalo, L. O. A1 - Tavecchio, F. A1 - Temnikov, P. A1 - Terzic, T. A1 - Tescaro, D. A1 - Teshima, M. A1 - Vankov, H. A1 - Wagner, R. M. A1 - Weitzel, Q. A1 - Zabalza, V. A1 - Zandanel, F. A1 - Zanin, R. A1 - Acciari, V. A. A1 - Arlen, T. A1 - Aune, T. A1 - Benbow, W. A1 - Boltuch, D. A1 - Bradbury, S. M. A1 - Buckley, J. H. A1 - Bugaev, V. A1 - Cannon, A. A1 - Cesarini, A. A1 - Ciupik, L. A1 - Cui, W. A1 - Dickherber, R. A1 - Errando, M. A1 - Falcone, A. A1 - Finley, J. P. A1 - Finnegan, G. A1 - Fortson, L. A1 - Furniss, A. A1 - Galante, N. A1 - Gall, D. A1 - Gillanders, G. H. A1 - Godambe, S. A1 - Grube, J. A1 - Guenette, R. A1 - Gyuk, G. A1 - Hanna, D. A1 - Holder, J. A1 - Huang, D. A1 - Hui, C. M. A1 - Humensky, T. B. A1 - Kaaret, P. A1 - Karlsson, N. A1 - Kertzman, M. A1 - Kieda, D. A1 - Konopelko, A. A1 - Krawczynski, H. A1 - Krennrich, F. A1 - Lang, M. J. A1 - Maier, G. A1 - McArthur, S. A1 - McCann, A. A1 - McCutcheon, M. A1 - Moriarty, P. A1 - Mukherjee, R. A1 - Ong, R. A1 - Otte, N. A1 - Pandel, D. A1 - Perkins, J. S. A1 - Pichel, A. A1 - Pohl, M. A1 - Quinn, J. A1 - Ragan, K. A1 - Reyes, L. C. A1 - Reynolds, P. T. A1 - Roache, E. A1 - Rose, H. J. A1 - Rovero, A. C. A1 - Schroedter, M. A1 - Sembroski, G. H. A1 - Senturk, G. D. A1 - Steele, D. A1 - Swordy, S. P. A1 - Tesic, G. A1 - Theiling, M. A1 - Thibadeau, S. A1 - Varlotta, A. A1 - Vincent, S. A1 - Wakely, S. P. A1 - Ward, J. E. A1 - Weekes, T. C. A1 - Weinstein, A. A1 - Weisgarber, T. A1 - Williams, D. A. A1 - Wood, M. A1 - Zitzer, B. A1 - Villata, M. A1 - Raiteri, C. M. A1 - Aller, H. D. A1 - Aller, M. F. A1 - Arkharov, A. A. A1 - Blinov, D. A. A1 - Calcidese, P. A1 - Chen, W. P. A1 - Efimova, N. V. A1 - Kimeridze, G. A1 - Konstantinova, T. S. A1 - Kopatskaya, E. N. A1 - Koptelova, E. A1 - Kurtanidze, O. M. A1 - Kurtanidze, S. O. A1 - Lahteenmaki, A. A1 - Larionov, V. M. A1 - Larionova, E. G. A1 - Larionova, L. V. A1 - Ligustri, R. A1 - Morozova, D. A. A1 - Nikolashvili, M. G. A1 - Sigua, L. A. A1 - Troitsky, I. S. A1 - Angelakis, E. A1 - Capalbi, M. A1 - Carraminana, A. A1 - Carrasco, L. A1 - Cassaro, P. A1 - de la Fuente, E. A1 - Gurwell, M. A. A1 - Kovalev, Y. Y. A1 - Kovalev, Yu. A. A1 - Krichbaum, T. P. A1 - Krimm, H. A. A1 - Leto, Paolo A1 - Lister, M. L. A1 - Maccaferri, G. A1 - Moody, J. W. A1 - Mori, Y. A1 - Nestoras, I. A1 - Orlati, A. A1 - Pagani, C. A1 - Pace, C. A1 - Pearson, R. A1 - Perri, M. A1 - Piner, B. G. A1 - Pushkarev, A. B. A1 - Ros, E. A1 - Sadun, A. C. A1 - Sakamoto, T. A1 - Tornikoski, M. A1 - Yatsu, Y. A1 - Zook, A. T1 - Insights into the high-energy gamma-Ray emission of markarian 501 fromextensive multifrequency observations in the fermi era JF - The astrophysical journal : an international review of spectroscopy and astronomical physics N2 - We report on the gamma-ray activity of the blazar Mrk 501 during the first 480 days of Fermi operation. We find that the average Large Area Telescope (LAT) gamma-ray spectrum of Mrk 501 can be well described by a single power-law function with a photon index of 1.78 +/- 0.03. While we observe relatively mild flux variations with the Fermi-LAT (within less than a factor of two), we detect remarkable spectral variability where the hardest observed spectral index within the LAT energy range is 1.52 +/- 0.14, and the softest one is 2.51 +/- 0.20. These unexpected spectral changes do not correlate with the measured flux variations above 0.3 GeV. In this paper, we also present the first results from the 4.5 month long multifrequency campaign (2009 March 15-August 1) on Mrk 501, which included the Very Long Baseline Array (VLBA), Swift, RXTE, MAGIC, and VERITAS, the F-GAMMA, GASP-WEBT, and other collaborations and instruments which provided excellent temporal and energy coverage of the source throughout the entire campaign. The extensive radio to TeV data set from this campaign provides us with the most detailed spectral energy distribution yet collected for this source during its relatively low activity. The average spectral energy distribution of Mrk 501 is well described by the standard one-zone synchrotron self-Compton (SSC) model. In the framework of this model, we find that the dominant emission region is characterized by a size less than or similar to 0.1 pc (comparable within a factor of few to the size of the partially resolved VLBA core at 15-43 GHz), and that the total jet power (similar or equal to 10(44) erg s(-1)) constitutes only a small fraction (similar to 10(-3)) of the Eddington luminosity. The energy distribution of the freshly accelerated radiating electrons required to fit the time-averaged data has a broken power-law form in the energy range 0.3 GeV-10 TeV, with spectral indices 2.2 and 2.7 below and above the break energy of 20 GeV. We argue that such a form is consistent with a scenario in which the bulk of the energy dissipation within the dominant emission zone of Mrk 501 is due to relativistic, proton-mediated shocks. We find that the ultrarelativistic electrons and mildly relativistic protons within the blazar zone, if comparable in number, are in approximate energy equipartition, with their energy dominating the jet magnetic field energy by about two orders of magnitude. KW - acceleration of particles KW - BL Lacertae objects: general KW - BL Lacertae objects: individual (Mrk 501) KW - galaxies: active KW - gamma rays: general KW - radiation mechanisms: non-thermal Y1 - 2011 U6 - https://doi.org/10.1088/0004-637X/727/2/129 SN - 0004-637X VL - 727 IS - 2 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Abdo, A. A. A1 - Ackermann, Margit A1 - Ajello, M. A1 - Allafort, A. J. A1 - Baldini, L. A1 - Ballet, J. A1 - Barbiellini, G. A1 - Baring, M. G. A1 - Bastieri, D. A1 - Bellazzini, R. A1 - Berenji, B. A1 - Blandford, R. D. A1 - Bloom, E. D. A1 - Bonamente, E. A1 - Borgland, A. W. A1 - Bouvier, A. A1 - Brandt, T. J. A1 - Bregeon, Johan A1 - Brigida, M. A1 - Bruel, P. A1 - Buehler, R. A1 - Buson, S. A1 - Caliandro, G. A. A1 - Cameron, R. A. A1 - Caraveo, P. A. A1 - Casandjian, J. M. A1 - Cecchi, C. A1 - Chaty, S. A1 - Chekhtman, A. A1 - Cheung, C. C. A1 - Chiang, J. A1 - Cillis, A. N. A1 - Ciprini, S. A1 - Claus, R. A1 - Cohen-Tanugi, J. A1 - Conrad, Jan A1 - Corbel, S. A1 - Cutini, S. A1 - de Angelis, A. A1 - de Palma, F. A1 - Dermer, C. D. A1 - Digel, S. W. A1 - do Couto e Silva, E. A1 - Drell, P. S. A1 - Drlica-Wagner, A. A1 - Dubois, R. A1 - Dumora, D. A1 - Favuzzi, C. A1 - Ferrara, E. C. A1 - Fortin, P. A1 - Frailis, M. A1 - Fukazawa, Y. A1 - Fukui, Y. A1 - Funk, S. A1 - Fusco, P. A1 - Gargano, F. A1 - Gasparrini, D. A1 - Gehrels, N. A1 - Germani, S. A1 - Giglietto, N. A1 - Giordano, F. A1 - Giroletti, M. A1 - Glanzman, T. A1 - Godfrey, G. A1 - Grenier, I. A. A1 - Grondin, M. -H. A1 - Guiriec, S. A1 - Hadasch, D. A1 - Hanabata, Y. A1 - Harding, A. K. A1 - Hayashida, M. A1 - Hayashi, K. A1 - Hays, E. A1 - Horan, D. A1 - Jackson, M. S. A1 - Johannesson, G. A1 - Johnson, A. S. A1 - Kamae, T. A1 - Katagiri, H. A1 - Kataoka, J. A1 - Kerr, M. A1 - Knoedlseder, J. A1 - Kuss, M. A1 - Lande, J. A1 - Latronico, L. A1 - Lee, S. -H. A1 - Lemoine-Goumard, M. A1 - Longo, F. A1 - Loparco, F. A1 - Lovellette, M. N. A1 - Lubrano, P. A1 - Madejski, G. M. A1 - Makeev, A. A1 - Mazziotta, Mario Nicola A1 - McEnery, J. E. A1 - Michelson, P. F. A1 - Mignani, R. P. A1 - Mitthumsiri, W. A1 - Mizuno, T. A1 - Moiseev, A. A. A1 - Monte, C. A1 - Monzani, M. E. A1 - Morselli, A. A1 - Moskalenko, I. V. A1 - Murgia, S. A1 - Naumann-Godo, M. A1 - Nolan, P. L. A1 - Norris, J. P. A1 - Nuss, E. A1 - Ohsugi, T. A1 - Okumura, A. A1 - Orlando, E. A1 - Ormes, J. F. A1 - Paneque, D. A1 - Parent, D. A1 - Pelassa, V. A1 - Pesce-Rollins, M. A1 - Pierbattista, M. A1 - Piron, F. A1 - Pohl, Martin A1 - Porter, T. A. A1 - Raino, S. A1 - Rando, R. A1 - Razzano, M. A1 - Reimer, O. A1 - Reposeur, T. A1 - Ritz, S. A1 - Romani, R. W. A1 - Roth, M. A1 - Sadrozinski, H. F. -W. A1 - Parkinson, P. M. Saz A1 - Sgro, C. A1 - Smith, D. A. A1 - Smith, P. D. A1 - Spandre, G. A1 - Spinelli, P. A1 - Strickman, M. S. A1 - Tajima, H. A1 - Takahashi, H. A1 - Takahashi, T. A1 - Tanaka, T. A1 - Thayer, J. G. A1 - Thayer, J. B. A1 - Thompson, D. J. A1 - Tibaldo, L. A1 - Tibolla, O. A1 - Torres, D. F. A1 - Tosti, G. A1 - Tramacere, A. A1 - Troja, E. A1 - Uchiyama, Y. A1 - Vandenbroucke, J. A1 - Vasileiou, V. A1 - Vianello, G. A1 - Vilchez, N. A1 - Vitale, V. A1 - Waite, A. P. A1 - Wang, P. A1 - Winer, B. L. A1 - Wood, K. S. A1 - Yamamoto, H. A1 - Yamazaki, R. A1 - Yang, Z. A1 - Ziegler, M. T1 - Observations of the young supernova remnant RX J1713.7-3946 with the fermi large area telescope JF - The astrophysical journal : an international review of spectroscopy and astronomical physics N2 - We present observations of the young supernova remnant (SNR) RX J1713.7-3946 with the Fermi Large Area Telescope (LAT). We clearly detect a source positionally coincident with the SNR. The source is extended with a best-fit extension of 0 degrees.55 +/- 0 degrees.04 matching the size of the non-thermal X-ray and TeV gamma-ray emission from the remnant. The positional coincidence and the matching extended emission allow us to identify the LAT source with SNR RX J1713.7-3946. The spectrum of the source can be described by a very hard power law with a photon index of Gamma = 1.5 +/- 0.1 that coincides in normalization with the steeper H. E. S. S.-detected gamma-ray spectrum at higher energies. The broadband gamma-ray emission is consistent with a leptonic origin as the dominant mechanism for the gamma-ray emission. KW - acceleration of particles KW - gamma rays: general KW - gamma rays: ISM KW - ISM: individual objects (RX J1713.7-3946) KW - ISM: supernova remnants KW - radiation mechanisms: non-thermal Y1 - 2011 U6 - https://doi.org/10.1088/0004-637X/734/1/28 SN - 0004-637X VL - 734 IS - 1 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Ackermann, Margit A1 - Ajello, M. A1 - Allafort, A. J. A1 - Baldini, L. A1 - Ballet, J. A1 - Barbiellini, G. A1 - Bastieri, D. A1 - Belfiore, A. A1 - Bellazzini, R. A1 - Berenji, B. A1 - Blandford, R. D. A1 - Bloom, E. D. A1 - Bonamente, E. A1 - Borgland, A. W. A1 - Bottacini, E. A1 - Brigida, M. A1 - Bruel, P. A1 - Buehler, R. A1 - Buson, S. A1 - Caliandro, G. A. A1 - Cameron, R. A. A1 - Caraveo, P. A. A1 - Casandjian, J. M. A1 - Cecchi, C. A1 - Chekhtman, A. A1 - Cheung, C. C. A1 - Chiang, J. A1 - Ciprini, S. A1 - Claus, R. A1 - Cohen-Tanugi, J. A1 - de Angelis, A. A1 - de Palma, F. A1 - Dermer, C. D. A1 - do Couto e Silva, E. A1 - Drell, P. S. A1 - Dumora, D. A1 - Favuzzi, C. A1 - Fegan, S. J. A1 - Focke, W. B. A1 - Fortin, P. A1 - Fukazawa, Y. A1 - Fusco, P. A1 - Gargano, F. A1 - Germani, S. A1 - Giglietto, N. A1 - Giordano, F. A1 - Giroletti, M. A1 - Glanzman, T. A1 - Godfrey, G. A1 - Grenier, I. A. A1 - Guillemot, L. A1 - Guiriec, S. A1 - Hadasch, D. A1 - Hanabata, Y. A1 - Harding, A. K. A1 - Hayashida, M. A1 - Hayashi, K. A1 - Hays, E. A1 - Johannesson, G. A1 - Johnson, A. S. A1 - Kamae, T. A1 - Katagiri, H. A1 - Kataoka, J. A1 - Kerr, M. A1 - Knoedlseder, J. A1 - Kuss, M. A1 - Lande, J. A1 - Latronico, L. A1 - Lee, S. -H. A1 - Longo, F. A1 - Loparco, F. A1 - Lott, B. A1 - Lovellette, M. N. A1 - Lubrano, P. A1 - Martin, P. A1 - Mazziotta, Mario Nicola A1 - McEnery, J. E. A1 - Mehault, J. A1 - Michelson, P. F. A1 - Mitthumsiri, W. A1 - Mizuno, T. A1 - Monte, C. A1 - Monzani, M. E. A1 - Morselli, A. A1 - Moskalenko, I. V. A1 - Murgia, S. A1 - Naumann-Godo, M. A1 - Nolan, P. L. A1 - Norris, J. P. A1 - Nuss, E. A1 - Ohsugi, T. A1 - Okumura, A. A1 - Orlando, E. A1 - Ormes, J. F. A1 - Ozaki, M. A1 - Paneque, D. A1 - Parent, D. A1 - Pesce-Rollins, M. A1 - Pierbattista, M. A1 - Piron, F. A1 - Pohl, Martin A1 - Prokhorov, D. A1 - Raino, S. A1 - Rando, R. A1 - Razzano, M. A1 - Reposeur, T. A1 - Ritz, S. A1 - Parkinson, P. M. Saz A1 - Sgro, C. A1 - Siskind, E. J. A1 - Smith, P. D. A1 - Spinelli, P. A1 - Strong, A. W. A1 - Takahashi, H. A1 - Tanaka, T. A1 - Thayer, J. G. A1 - Thayer, J. B. A1 - Thompson, D. J. A1 - Tibaldo, L. A1 - Torres, D. F. A1 - Tosti, G. A1 - Tramacere, A. A1 - Troja, E. A1 - Uchiyama, Y. A1 - Vandenbroucke, J. A1 - Vasileiou, V. A1 - Vianello, G. A1 - Vitale, V. A1 - Waite, A. P. A1 - Wang, P. A1 - Winer, B. L. A1 - Wood, K. S. A1 - Yang, Z. A1 - Zimmer, S. A1 - Bontemps, S. T1 - A cocoon of freshly accelerated cosmic rays detected by fermi in the cygnus superbubble JF - Science N2 - The origin of Galactic cosmic rays is a century-long puzzle. Indirect evidence points to their acceleration by supernova shockwaves, but we know little of their escape from the shock and their evolution through the turbulent medium surrounding massive stars. Gamma rays can probe their spreading through the ambient gas and radiation fields. The Fermi Large Area Telescope (LAT) has observed the star-forming region of Cygnus X. The 1- to 100-gigaelectronvolt images reveal a 50-parsec-wide cocoon of freshly accelerated cosmic rays that flood the cavities carved by the stellar winds and ionization fronts from young stellar clusters. It provides an example to study the youth of cosmic rays in a superbubble environment before they merge into the older Galactic population. Y1 - 2011 U6 - https://doi.org/10.1126/science.1210311 SN - 0036-8075 VL - 334 IS - 6059 SP - 1103 EP - 1107 PB - American Assoc. for the Advancement of Science CY - Washington ER - TY - JOUR A1 - De Angelis, A. A1 - Tatischeff, V. A1 - Grenier, I. A. A1 - McEnery, J. A1 - Mallamaci, Manuela A1 - Tavani, M. A1 - Oberlack, U. A1 - Hanlon, L. A1 - Walter, R. A1 - Argan, A. A1 - Von Ballmoos, P. A1 - Bulgarelli, A. A1 - Bykov, A. A1 - Hernanz, M. A1 - Kanbach, G. A1 - Kuvvetli, I. A1 - Pearce, M. A1 - Zdziarski, A. A1 - Conrad, J. A1 - Ghisellini, G. A1 - Harding, A. A1 - Isern, J. A1 - Leising, M. A1 - Longo, F. A1 - Madejski, G. A1 - Martinez, M. A1 - Mazziotta, Mario Nicola A1 - Paredes, J. M. A1 - Pohl, Martin A1 - Rando, R. A1 - Razzano, M. A1 - Aboudan, A. A1 - Ackermann, M. A1 - Addazi, A. A1 - Ajello, M. A1 - Albertus, C. A1 - Alvarez, J. M. A1 - Ambrosi, G. A1 - Anton, S. A1 - Antonelli, L. A. A1 - Babic, A. A1 - Baibussinov, B. A1 - Balbom, M. A1 - Baldini, L. A1 - Balman, S. A1 - Bambi, C. A1 - Barres de Almeida, U. A1 - Barrio, J. A. A1 - Bartels, R. A1 - Bastieri, D. A1 - Bednarek, W. A1 - Bernard, D. A1 - Bernardini, E. A1 - Bernasconi, T. A1 - Bertucci, B. A1 - Biland, A. A1 - Bissaldi, E. A1 - Boettcher, M. A1 - Bonvicini, V. A1 - Bosch-Ramon, V. A1 - Bottacini, E. A1 - Bozhilov, V. A1 - Bretz, T. A1 - Branchesi, M. A1 - Brdar, V. A1 - Bringmann, T. A1 - Brogna, A. A1 - Jorgensen, C. Budtz A1 - Busetto, G. A1 - Buson, S. A1 - Busso, M. A1 - Caccianiga, A. A1 - Camera, S. A1 - Campana, R. A1 - Caraveo, P. A1 - Cardillo, M. A1 - Carlson, P. A1 - Celestin, S. A1 - Cermeno, M. A1 - Chen, A. A1 - Cheung, C. C. A1 - Churazov, E. A1 - Ciprini, S. A1 - Coc, A. A1 - Colafrancesco, S. A1 - Coleiro, A. A1 - Collmar, W. A1 - Coppi, P. A1 - Curado da Silva, R. A1 - Cutini, S. A1 - De Lotto, B. A1 - de Martino, D. A1 - De Rosa, A. A1 - Del Santo, M. A1 - Delgado, L. A1 - Diehl, R. A1 - Dietrich, S. A1 - Dolgov, A. D. A1 - Dominguez, A. A1 - Prester, D. Dominis A1 - Donnarumma, I. A1 - Dorner, D. A1 - Doro, M. A1 - Dutra, M. A1 - Elsaesser, D. A1 - Fabrizio, M. A1 - Fernandez-Barral, A. A1 - Fioretti, V. A1 - Foffano, L. A1 - Formato, V. A1 - Fornengo, N. A1 - Foschini, L. A1 - Franceschini, A. A1 - Franckowiak, A. A1 - Funk, S. A1 - Fuschino, F. A1 - Gaggero, D. A1 - Galanti, G. A1 - Gargano, F. A1 - Gasparrini, D. A1 - Gehrz, R. A1 - Giammaria, P. A1 - Giglietto, N. A1 - Giommi, P. A1 - Giordano, F. A1 - Giroletti, M. A1 - Ghirlanda, G. A1 - Godinovic, N. A1 - Gouiffes, C. A1 - Grove, J. E. A1 - Hamadache, C. A1 - Hartmann, D. H. A1 - Hayashida, M. A1 - Hryczuk, A. A1 - Jean, P. A1 - Johnson, T. A1 - Jose, J. A1 - Kaufmann, S. A1 - Khelifi, B. A1 - Kiener, J. A1 - Knodlseder, J. A1 - Kolem, M. A1 - Kopp, J. A1 - Kozhuharov, V. A1 - Labanti, C. A1 - Lalkovski, S. A1 - Laurent, P. A1 - Limousin, O. A1 - Linares, M. A1 - Lindfors, E. A1 - Lindner, M. A1 - Liu, J. A1 - Lombardi, S. A1 - Loparco, F. A1 - Lopez-Coto, R. A1 - Lopez Moya, M. A1 - Lott, B. A1 - Lubrano, P. A1 - Malyshev, D. A1 - Mankuzhiyil, N. A1 - Mannheim, K. A1 - Marcha, M. J. A1 - Marciano, A. A1 - Marcote, B. A1 - Mariotti, M. A1 - Marisaldi, M. A1 - McBreen, S. A1 - Mereghetti, S. A1 - Merle, A. A1 - Mignani, R. A1 - Minervini, G. A1 - Moiseev, A. A1 - Morselli, A. A1 - Moura, F. A1 - Nakazawa, K. A1 - Nava, L. A1 - Nieto, D. A1 - Orienti, M. A1 - Orio, M. A1 - Orlando, E. A1 - Orleanski, P. A1 - Paiano, S. A1 - Paoletti, R. A1 - Papitto, A. A1 - Pasquato, M. A1 - Patricelli, B. A1 - Perez-Garcia, M. A. A1 - Persic, M. A1 - Piano, G. A1 - Pichel, A. A1 - Pimenta, M. A1 - Pittori, C. A1 - Porter, T. A1 - Poutanen, J. A1 - Prandini, E. A1 - Prantzos, N. A1 - Produit, N. A1 - Profumo, S. A1 - Queiroz, F. S. A1 - Raino, S. A1 - Raklev, A. A1 - Regis, M. A1 - Reichardt, I. A1 - Rephaeli, Y. A1 - Rico, J. A1 - Rodejohann, W. A1 - Fernandez, G. Rodriguez A1 - Roncadelli, M. A1 - Roso, L. A1 - Rovero, A. A1 - Ruffini, R. A1 - Sala, G. A1 - Sanchez-Conde, M. A. A1 - Santangelo, A. A1 - Parkinson, P. Saz A1 - Sbarrato, T. A1 - Shearer, A. A1 - Shellard, R. A1 - Short, K. A1 - Siegert, T. A1 - Siqueira, C. A1 - Spinelli, P. A1 - Stamerra, A. A1 - Starrfield, S. A1 - Strong, A. A1 - Strumke, I. A1 - Tavecchio, F. A1 - Taverna, R. A1 - Terzic, T. A1 - Thompson, D. J. A1 - Tibolla, O. A1 - Torres, D. F. A1 - Turolla, R. A1 - Ulyanov, A. A1 - Ursi, A. A1 - Vacchi, A. A1 - Van den Abeele, J. A1 - Vankova-Kirilovai, G. A1 - Venter, C. A1 - Verrecchia, F. A1 - Vincent, P. A1 - Wang, X. A1 - Weniger, C. A1 - Wu, X. A1 - Zaharijas, G. A1 - Zampieri, L. A1 - Zane, S. A1 - Zimmer, S. A1 - Zoglauer, A. T1 - Science with e-ASTROGAM A space mission for MeV-GeV gamma-ray astrophysics JF - Journal of High Energy Astrophysics Y1 - 2018 U6 - https://doi.org/10.1016/j.jheap.2018.07.001 SN - 2214-4048 SN - 2214-4056 VL - 19 SP - 1 EP - 106 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - De Angelis, A. A1 - Tatischeff, V. A1 - Tavani, M. A1 - Oberlack, U. A1 - Grenier, I. A1 - Hanloni, L. A1 - Walter, R. A1 - Argan, A. A1 - Von Ballmoos, P. A1 - Bulgarelli, A. A1 - Donnarumma, I. A1 - Hernanz, M. A1 - Kuvvetli, I. A1 - Pearce, M. A1 - Zdziarski, A. A1 - Aboudan, A. A1 - Ajello, M. A1 - Ambrosi, G. A1 - Bernard, D. A1 - Bernardini, E. A1 - Bonvicini, V. A1 - Brogna, A. A1 - Branchesi, M. A1 - Budtz-Jorgensen, C. A1 - Bykov, A. M. A1 - Campana, R. A1 - Cardillo, M. A1 - Coppi, P. A1 - De Martino, D. A1 - Diehl, R. A1 - Doro, M. A1 - Fioretti, V. A1 - Funk, S. A1 - Ghisellini, G. A1 - Grove, E. A1 - Hamadache, C. A1 - Hartmann, D. H. A1 - Hayashida, M. A1 - Isern, J. A1 - Kanbach, G. A1 - Kiener, J. A1 - Knodlseder, J. A1 - Labanti, C. A1 - Laurent, P. A1 - Limousin, O. A1 - Longo, F. A1 - Mannheim, K. A1 - Marisaldi, M. A1 - Martinez, M. A1 - Mazziotta, Mario Nicola A1 - McEnery, J. A1 - Mereghetti, S. A1 - Minervini, G. A1 - Moiseev, A. A1 - Morselli, A. A1 - Nakazawa, K. A1 - Orleanski, P. A1 - Paredes, J. M. A1 - Patricelli, B. A1 - Pevre, J. A1 - Piano, G. A1 - Pohl, Martin A1 - Ramarijaona, H. A1 - Rando, R. A1 - Reichardt, I. A1 - Roncadelli, M. A1 - Silva, R. A1 - Tavecchio, F. A1 - Thompson, D. J. A1 - Turolla, R. A1 - Ulyanov, A. A1 - Vacchi, A. A1 - Wu, X. A1 - Zoglauer, A. T1 - The e-ASTROGAM mission Exploring the extreme Universe with gamma rays in the MeV - GeV range JF - Experimental astronomy : an international journal on astronomical instrumentation and data analysis N2 - e-ASTROGAM (‘enhanced ASTROGAM’) is a breakthrough Observatory space mission, with a detector composed by a Silicon tracker, a calorimeter, and an anticoincidence system, dedicated to the study of the non-thermal Universe in the photon energy range from 0.3 MeV to 3 GeV – the lower energy limit can be pushed to energies as low as 150 keV, albeit with rapidly degrading angular resolution, for the tracker, and to 30 keV for calorimetric detection. The mission is based on an advanced space-proven detector technology, with unprecedented sensitivity, angular and energy resolution, combined with polarimetric capability. Thanks to its performance in the MeV-GeV domain, substantially improving its predecessors, e-ASTROGAM will open a new window on the non-thermal Universe, making pioneering observations of the most powerful Galactic and extragalactic sources, elucidating the nature of their relativistic outflows and their effects on the surroundings. With a line sensitivity in the MeV energy range one to two orders of magnitude better than previous generation instruments, e-ASTROGAM will determine the origin of key isotopes fundamental for the understanding of supernova explosion and the chemical evolution of our Galaxy. The mission will provide unique data of significant interest to a broad astronomical community, complementary to powerful observatories such as LIGO-Virgo-GEO600-KAGRA, SKA, ALMA, E-ELT, TMT, LSST, JWST, Athena, CTA, IceCube, KM3NeT, and the promise of eLISA. KW - High-Energy Gamma-Ray Astronomy KW - High-Energy Astrophysics KW - Nuclear Astrophysics KW - Compton and Pair Creation Telescope KW - Gamma-Ray Bursts KW - Active Galactic Nuclei KW - Jets KW - Outflows KW - Multiwavelength Observations of the Universe KW - Counterparts of gravitational waves KW - Fermi KW - Dark Matter KW - Nucleosynthesis KW - Early Universe KW - Supernovae KW - Cosmic Rays KW - Cosmic Antimatter Y1 - 2017 U6 - https://doi.org/10.1007/s10686-017-9533-6 SN - 0922-6435 SN - 1572-9508 VL - 44 SP - 25 EP - 82 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - Denton, Richard E. A1 - Ofman, L. A1 - Shprits, Yuri Y. A1 - Bortnik, J. A1 - Millan, R. M. A1 - Rodger, C. J. A1 - da Silva, C. L. A1 - Rogers, B. N. A1 - Hudson, M. K. A1 - Liu, K. A1 - Min, K. A1 - Glocer, A. A1 - Komar, C. T1 - Pitch Angle Scattering of Sub-MeV Relativistic Electrons by Electromagnetic Ion Cyclotron Waves JF - Journal of geophysical research : Space physics N2 - Electromagnetic ion cyclotron (EMIC) waves have long been considered to be a significant loss mechanism for relativistic electrons. This has most often been attributed to resonant interactions with the highest amplitude waves. But recent observations have suggested that the dominant energy of electrons precipitated to the atmosphere may often be relatively low, less than 1 MeV, whereas the minimum resonant energy of the highest amplitude waves is often greater than 2 MeV. Here we use relativistic electron test particle simulations in the wavefields of a hybrid code simulation of EMIC waves in dipole geometry in order to show that significant pitch angle scattering can occur due to interaction with low-amplitude short-wavelength EMIC waves. In the case we examined, these waves are in the H band (at frequencies above the He+ gyrofrequency), even though the highest amplitude waves were in the He band frequency range (below the He+ gyrofrequency). We also present wave power distributions for 29 EMIC simulations in straight magnetic field line geometry that show that the high wave number portion of the spectrum is in every case mostly due to the H band waves. Though He band waves are often associated with relativistic electron precipitation, it is possible that the He band waves do not directly scatter the sub-megaelectron volts (sub-MeV) electrons, but that the presence of He band waves is associated with high plasma density which lowers the minimum resonant energy so that these electrons can more easily resonate with the H band waves. KW - electromagnetic ion cyclotron waves KW - EMIC KW - relativistic electron precipitation KW - pitch angle scattering KW - wave particle interaction KW - radiation belts Y1 - 2019 U6 - https://doi.org/10.1029/2018JA026384 SN - 2169-9402 VL - 124 IS - 7 SP - 5610 EP - 5626 PB - American Geophysical Union CY - Washington ER - TY - JOUR A1 - Medrano-T., R. O. A1 - Baptista, Murilo da Silva A1 - Caldas, Ibere Luiz T1 - Shilnikov homoclinic orbit bifurcations in the Chua’s circuit JF - Chaos : an interdisciplinary journal of nonlinear science N2 - We analytically describe the complex scenario of homoclinic bifurcations in the Chua’s circuit. We obtain a general scaling law that gives the ratio between bifurcation parameters of different nearby homoclinic orbits. As an application of this theoretical approach, we estimate the number of higher order subsidiary homoclinic orbits that appear between two consecutive lower order subsidiary orbits. Our analytical finds might be valid for a large class of dynamical systems and are numerically confirmed in the parameter space of the Chua’s circuit. Shilnikov homoclinic orbits are trajectories that depart from a fixed saddle-focus point, with specific eigenvalues, and return to it after an infinite amount of time (that is also true to time reversal evolution). That results in an orbit that is unstable and has an infinite period. These two main characteristics contribute in the hardness for its observation in a dynamical system as well as in nature. However, its presence reveals fundamental characteristics of the system involved, as the existence of unstable periodic orbits embedded in a chaotic set. Once the unstable periodic orbits give invariants quantities of this set,1 the Shilnikov homoclinic orbits are also related to the characteristics of the chaotic set. Their connection with the fundamental dynamical properties is verified in a wide variety of systems. A series of numerical and experimental investigations reveal how Shilnikov homoclinic orbits, in the vicinity of a chaotic attractor, determine its dynamical and topological properties.4 Thus, the Shilnikov orbits are related to the returning time of the trajectory of a CO2 laser,5 also to the topology of a glow-discharge system.6 Moreover, some class of spiking neurons are modeled by chaos governed by such orbits,7,8 and their presence are connected to the intermittence present in rabbit arteries.9 These orbits are shown to be behind the mechanism of noise-induced phenomena,10 and they are also responsible for the dynamics of an electrochemical oscillator.11 In this work, we contribute to the understanding of how Shilnikov homoclinic orbits appear on the parameter space of systems as the ones above mentioned, by showing that these orbits are not only distributed following an universal rule but also exist for large parameter variations. We then confirm our previsions in the Chua’s circuit system Y1 - 2006 U6 - https://doi.org/10.1063/1.2401060 SN - 1054-1500 VL - 16 IS - 4 PB - American Institute of Physics CY - Melville ER - TY - JOUR A1 - Middeldorp, Christel M. A1 - Mahajan, Anubha A1 - Horikoshi, Momoko A1 - Robertson, Neil R. A1 - Beaumont, Robin N. A1 - Bradfield, Jonathan P. A1 - Bustamante, Mariona A1 - Cousminer, Diana L. A1 - Day, Felix R. A1 - De Silva, N. Maneka A1 - Guxens, Monica A1 - Mook-Kanamori, Dennis O. A1 - St Pourcain, Beate A1 - Warrington, Nicole M. A1 - Adair, Linda S. A1 - Ahlqvist, Emma A1 - Ahluwalia, Tarunveer Singh A1 - Almgren, Peter A1 - Ang, Wei A1 - Atalay, Mustafa A1 - Auvinen, Juha A1 - Bartels, Meike A1 - Beckmann, Jacques S. A1 - Bilbao, Jose Ramon A1 - Bond, Tom A1 - Borja, Judith B. A1 - Cavadino, Alana A1 - Charoen, Pimphen A1 - Chen, Zhanghua A1 - Coin, Lachlan A1 - Cooper, Cyrus A1 - Curtin, John A. A1 - Custovic, Adnan A1 - Das, Shikta A1 - Davies, Gareth E. A1 - Dedoussis, George V. A1 - Duijts, Liesbeth A1 - Eastwood, Peter R. A1 - Eliasen, Anders U. A1 - Elliott, Paul A1 - Eriksson, Johan G. A1 - Estivill, Xavier A1 - Fadista, Joao A1 - Fedko, Iryna O. A1 - Frayling, Timothy M. A1 - Gaillard, Romy A1 - Gauderman, W. James A1 - Geller, Frank A1 - Gilliland, Frank A1 - Gilsanz, Vincente A1 - Granell, Raquel A1 - Grarup, Niels A1 - Groop, Leif A1 - Hadley, Dexter A1 - Hakonarson, Hakon A1 - Hansen, Torben A1 - Hartman, Catharina A. A1 - Hattersley, Andrew T. A1 - Hayes, M. Geoffrey A1 - Hebebrand, Johannes A1 - Heinrich, Joachim A1 - Helgeland, Oyvind A1 - Henders, Anjali K. A1 - Henderson, John A1 - Henriksen, Tine B. A1 - Hirschhorn, Joel N. A1 - Hivert, Marie-France A1 - Hocher, Berthold A1 - Holloway, John W. A1 - Holt, Patrick A1 - Hottenga, Jouke-Jan A1 - Hypponen, Elina A1 - Iniguez, Carmen A1 - Johansson, Stefan A1 - Jugessur, Astanand A1 - Kahonen, Mika A1 - Kalkwarf, Heidi J. A1 - Kaprio, Jaakko A1 - Karhunen, Ville A1 - Kemp, John P. A1 - Kerkhof, Marjan A1 - Koppelman, Gerard H. A1 - Korner, Antje A1 - Kotecha, Sailesh A1 - Kreiner-Moller, Eskil A1 - Kulohoma, Benard A1 - Kumar, Ashish A1 - Kutalik, Zoltan A1 - Lahti, Jari A1 - Lappe, Joan M. A1 - Larsson, Henrik A1 - Lehtimaki, Terho A1 - Lewin, Alexandra M. A1 - Li, Jin A1 - Lichtenstein, Paul A1 - Lindgren, Cecilia M. A1 - Lindi, Virpi A1 - Linneberg, Allan A1 - Liu, Xueping A1 - Liu, Jun A1 - Lowe, William L. A1 - Lundstrom, Sebastian A1 - Lyytikainen, Leo-Pekka A1 - Ma, Ronald C. W. A1 - Mace, Aurelien A1 - Magi, Reedik A1 - Magnus, Per A1 - Mamun, Abdullah A. A1 - Mannikko, Minna A1 - Martin, Nicholas G. A1 - Mbarek, Hamdi A1 - McCarthy, Nina S. A1 - Medland, Sarah E. A1 - Melbye, Mads A1 - Melen, Erik A1 - Mohlke, Karen L. A1 - Monnereau, Claire A1 - Morgen, Camilla S. A1 - Morris, Andrew P. A1 - Murray, Jeffrey C. A1 - Myhre, Ronny A1 - Najman, Jackob M. A1 - Nivard, Michel G. A1 - Nohr, Ellen A. A1 - Nolte, Ilja M. A1 - Ntalla, Ioanna A1 - Oberfield, Sharon E. A1 - Oken, Emily A1 - Oldehinkel, Albertine J. A1 - Pahkala, Katja A1 - Palviainen, Teemu A1 - Panoutsopoulou, Kalliope A1 - Pedersen, Oluf A1 - Pennell, Craig E. A1 - Pershagen, Goran A1 - Pitkanen, Niina A1 - Plomin, Robert A1 - Power, Christine A1 - Prasad, Rashmi B. A1 - Prokopenko, Inga A1 - Pulkkinen, Lea A1 - Raikkonen, Katri A1 - Raitakari, Olli T. A1 - Reynolds, Rebecca M. A1 - Richmond, Rebecca C. A1 - Rivadeneira, Fernando A1 - Rodriguez, Alina A1 - Rose, Richard J. A1 - Salem, Rany A1 - Santa-Marina, Loreto A1 - Saw, Seang-Mei A1 - Schnurr, Theresia M. A1 - Scott, James G. A1 - Selzam, Saskia A1 - Shepherd, John A. A1 - Simpson, Angela A1 - Skotte, Line A1 - Sleiman, Patrick M. A. A1 - Snieder, Harold A1 - Sorensen, Thorkild I. A. A1 - Standl, Marie A1 - Steegers, Eric A. P. A1 - Strachan, David P. A1 - Straker, Leon A1 - Strandberg, Timo A1 - Taylor, Michelle A1 - Teo, Yik-Ying A1 - Thiering, Elisabeth A1 - Torrent, Maties A1 - Tyrrell, Jessica A1 - Uitterlinden, Andre G. A1 - van Beijsterveldt, Toos A1 - van der Most, Peter J. A1 - van Duijn, Cornelia M. A1 - Viikari, Jorma A1 - Vilor-Tejedor, Natalia A1 - Vogelezang, Suzanne A1 - Vonk, Judith M. A1 - Vrijkotte, Tanja G. M. A1 - Vuoksimaa, Eero A1 - Wang, Carol A. A1 - Watkins, William J. A1 - Wichmann, H-Erich A1 - Willemsen, Gonneke A1 - Williams, Gail M. A1 - Wilson, James F. A1 - Wray, Naomi R. A1 - Xu, Shujing A1 - Xu, Cheng-Jian A1 - Yaghootkar, Hanieh A1 - Yi, Lu A1 - Zafarmand, Mohammad Hadi A1 - Zeggini, Eleftheria A1 - Zemel, Babette S. A1 - Hinney, Anke A1 - Lakka, Timo A. A1 - Whitehouse, Andrew J. O. A1 - Sunyer, Jordi A1 - Widen, Elisabeth E. A1 - Feenstra, Bjarke A1 - Sebert, Sylvain A1 - Jacobsson, Bo A1 - Njolstad, Pal R. A1 - Stoltenberg, Camilla A1 - Smith, George Davey A1 - Lawlor, Debbie A. A1 - Paternoster, Lavinia A1 - Timpson, Nicholas J. A1 - Ong, Ken K. A1 - Bisgaard, Hans A1 - Bonnelykke, Klaus A1 - Jaddoe, Vincent W. V. A1 - Tiemeier, Henning A1 - Jarvelin, Marjo-Riitta A1 - Evans, David M. A1 - Perry, John R. B. A1 - Grant, Struan F. A. A1 - Boomsma, Dorret I. A1 - Freathy, Rachel M. A1 - McCarthy, Mark I. A1 - Felix, Janine F. T1 - The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia BT - design, results and future prospects JF - European journal of epidemiology N2 - The impact of many unfavorable childhood traits or diseases, such as low birth weight and mental disorders, is not limited to childhood and adolescence, as they are also associated with poor outcomes in adulthood, such as cardiovascular disease. Insight into the genetic etiology of childhood and adolescent traits and disorders may therefore provide new perspectives, not only on how to improve wellbeing during childhood, but also how to prevent later adverse outcomes. To achieve the sample sizes required for genetic research, the Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia were established. The majority of the participating cohorts are longitudinal population-based samples, but other cohorts with data on early childhood phenotypes are also involved. Cohorts often have a broad focus and collect(ed) data on various somatic and psychiatric traits as well as environmental factors. Genetic variants have been successfully identified for multiple traits, for example, birth weight, atopic dermatitis, childhood BMI, allergic sensitization, and pubertal growth. Furthermore, the results have shown that genetic factors also partly underlie the association with adult traits. As sample sizes are still increasing, it is expected that future analyses will identify additional variants. This, in combination with the development of innovative statistical methods, will provide detailed insight on the mechanisms underlying the transition from childhood to adult disorders. Both consortia welcome new collaborations. Policies and contact details are available from the corresponding authors of this manuscript and/or the consortium websites. KW - Genetics KW - Consortium KW - Childhood traits and disorders KW - Longitudinal Y1 - 2019 U6 - https://doi.org/10.1007/s10654-019-00502-9 SN - 0393-2990 SN - 1573-7284 VL - 34 IS - 3 SP - 279 EP - 300 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - Noonan, Michael J. A1 - Tucker, Marlee A. A1 - Fleming, Christen H. A1 - Akre, Thomas S. A1 - Alberts, Susan C. A1 - Ali, Abdullahi H. A1 - Altmann, Jeanne A1 - Antunes, Pamela Castro A1 - Belant, Jerrold L. A1 - Beyer, Dean A1 - Blaum, Niels A1 - Boehning-Gaese, Katrin A1 - Cullen Jr, Laury A1 - de Paula, Rogerio Cunha A1 - Dekker, Jasja A1 - Drescher-Lehman, Jonathan A1 - Farwig, Nina A1 - Fichtel, Claudia A1 - Fischer, Christina A1 - Ford, Adam T. A1 - Goheen, Jacob R. A1 - Janssen, Rene A1 - Jeltsch, Florian A1 - Kauffman, Matthew A1 - Kappeler, Peter M. A1 - Koch, Flavia A1 - LaPoint, Scott A1 - Markham, A. Catherine A1 - Medici, Emilia Patricia A1 - Morato, Ronaldo G. A1 - Nathan, Ran A1 - Oliveira-Santos, Luiz Gustavo R. A1 - Olson, Kirk A. A1 - Patterson, Bruce D. A1 - Paviolo, Agustin A1 - Ramalho, Emiliano Estero A1 - Rosner, Sascha A1 - Schabo, Dana G. A1 - Selva, Nuria A1 - Sergiel, Agnieszka A1 - da Silva, Marina Xavier A1 - Spiegel, Orr A1 - Thompson, Peter A1 - Ullmann, Wiebke A1 - Zieba, Filip A1 - Zwijacz-Kozica, Tomasz A1 - Fagan, William F. A1 - Mueller, Thomas A1 - Calabrese, Justin M. T1 - A comprehensive analysis of autocorrelation and bias in home range estimation JF - Ecological monographs : a publication of the Ecological Society of America. N2 - Home range estimation is routine practice in ecological research. While advances in animal tracking technology have increased our capacity to collect data to support home range analysis, these same advances have also resulted in increasingly autocorrelated data. Consequently, the question of which home range estimator to use on modern, highly autocorrelated tracking data remains open. This question is particularly relevant given that most estimators assume independently sampled data. Here, we provide a comprehensive evaluation of the effects of autocorrelation on home range estimation. We base our study on an extensive data set of GPS locations from 369 individuals representing 27 species distributed across five continents. We first assemble a broad array of home range estimators, including Kernel Density Estimation (KDE) with four bandwidth optimizers (Gaussian reference function, autocorrelated‐Gaussian reference function [AKDE], Silverman's rule of thumb, and least squares cross‐validation), Minimum Convex Polygon, and Local Convex Hull methods. Notably, all of these estimators except AKDE assume independent and identically distributed (IID) data. We then employ half‐sample cross‐validation to objectively quantify estimator performance, and the recently introduced effective sample size for home range area estimation ( N̂ area ) to quantify the information content of each data set. We found that AKDE 95% area estimates were larger than conventional IID‐based estimates by a mean factor of 2. The median number of cross‐validated locations included in the hold‐out sets by AKDE 95% (or 50%) estimates was 95.3% (or 50.1%), confirming the larger AKDE ranges were appropriately selective at the specified quantile. Conversely, conventional estimates exhibited negative bias that increased with decreasing N̂ area. To contextualize our empirical results, we performed a detailed simulation study to tease apart how sampling frequency, sampling duration, and the focal animal's movement conspire to affect range estimates. Paralleling our empirical results, the simulation study demonstrated that AKDE was generally more accurate than conventional methods, particularly for small N̂ area. While 72% of the 369 empirical data sets had >1,000 total observations, only 4% had an N̂ area >1,000, where 30% had an N̂ area <30. In this frequently encountered scenario of small N̂ area, AKDE was the only estimator capable of producing an accurate home range estimate on autocorrelated data. KW - animal movement KW - kernel density estimation KW - local convex hull KW - minimum convex polygon KW - range distribution KW - space use KW - telemetry KW - tracking data Y1 - 2018 U6 - https://doi.org/10.1002/ecm.1344 SN - 0012-9615 SN - 1557-7015 VL - 89 IS - 2 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Nunes-Nesi, Adriano A1 - Alseekh, Saleh A1 - de Oliveira Silva, Franklin Magnum A1 - Omranian, Nooshin A1 - Lichtenstein, Gabriel A1 - Mirnezhad, Mohammad A1 - Romero Gonzalez, Roman R. A1 - Sabio y Garcia, Julia A1 - Conte, Mariana A1 - Leiss, Kirsten A. A1 - Klinkhamer, Peter Gerardus Leonardus A1 - Nikoloski, Zoran A1 - Carrari, Fernando A1 - Fernie, Alisdair R. T1 - Identification and characterization of metabolite quantitative trait loci in tomato leaves and comparison with those reported for fruits and seeds JF - Metabolomics N2 - IntroductionTo date, most studies of natural variation and metabolite quantitative trait loci (mQTL) in tomato have focused on fruit metabolism, leaving aside the identification of genomic regions involved in the regulation of leaf metabolism.ObjectiveThis study was conducted to identify leaf mQTL in tomato and to assess the association of leaf metabolites and physiological traits with the metabolite levels from other tissues.MethodsThe analysis of components of leaf metabolism was performed by phenotypying 76 tomato ILs with chromosome segments of the wild species Solanum pennellii in the genetic background of a cultivated tomato (S. lycopersicum) variety M82. The plants were cultivated in two different environments in independent years and samples were harvested from mature leaves of non-flowering plants at the middle of the light period. The non-targeted metabolite profiling was obtained by gas chromatography time-of-flight mass spectrometry (GC-TOF-MS). With the data set obtained in this study and already published metabolomics data from seed and fruit, we performed QTL mapping, heritability and correlation analyses.ResultsChanges in metabolite contents were evident in the ILs that are potentially important with respect to stress responses and plant physiology. By analyzing the obtained data, we identified 42 positive and 76 negative mQTL involved in carbon and nitrogen metabolism.ConclusionsOverall, these findings allowed the identification of S. lycopersicum genome regions involved in the regulation of leaf primary carbon and nitrogen metabolism, as well as the association of leaf metabolites with metabolites from seeds and fruits. KW - Metabolite QTL KW - Tomato KW - Leaf metabolism KW - Metabolite network Y1 - 2019 U6 - https://doi.org/10.1007/s11306-019-1503-8 SN - 1573-3882 SN - 1573-3890 VL - 15 IS - 46 PB - Springer CY - New York ER -