TY  - JOUR
A1  - David Coy, Ericsson
A1  - Enrique Cuca, Luis
A1  - Sefkow, Michael
T1  - Pd-NHC catalyzed biaryl coupling by direct C-H Activation-A Novel strategy for the synthesis of dibenzocyclooctane lignans
JF  - Synthetic communications : an international journal for rapid communication of synthetic organic chemistry
N2  - Cross-coupling reactions, such as Buchwald-Hartwig arylamination and direct intramolecular biaryl coupling by C-H activation, were carried out using various Palladium-N-heterocyclic carbenes (Pd-NHC) as catalysts. The yields were good to excellent. The latter strategy was adopted to transform two dibenzylbutane lignans, isolated from the leaves of Ocotea macrophylla (Lauraceae), into the corresponding dibenzocyclooctane lignans in good overall yields. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications (R) to view the free supplemental file.
KW  - Cross-coupling reactions
KW  - dibenzylbutane
KW  - dibenzocyclooctane
KW  - lignans
KW  - N-heterocyclic carbenes (NHC)
Y1  - 2011
U6  - https://doi.org/10.1080/00397910903531755
SN  - 0039-7911
VL  - 41
IS  - 1
SP  - 41
EP  - 51
PB  - Taylor & Francis Group
CY  - Philadelphia
ER  - 
TY  - JOUR
A1  - Kamlage, Stefan
A1  - Sefkow, Michael
A1  - Peter, Martin G.
T1  - A short synthesis of biologically active lignan analogues
N2  - beta-Benzyl-gamma-butyrolactones were synthesized in four transition metal catalysed reactions from butynediol, and alkylated to afford new, biologically active lignan analogues.
Y1  - 2001
ER  - 
TY  - THES
A1  - Sefkow, Michael
T1  - Funktionelle Aromaten : neue Konzepte zur stereoselektiven Synthese phenolischer Naturstoffe und zur Derivatisierung aromatischer Verbindungen
Y1  - 2001
ER  - 
TY  - JOUR
A1  - Kamlage, Stefan
A1  - Sefkow, Michael
A1  - Peter, Martin G.
T1  - Cross coupling of benzylic bromides and vinyl stannanes
Y1  - 1999
ER  -