TY  - JOUR
A1  - Saparin, P. I.
A1  - Thomsen, J. S.
A1  - Prohaska, Steffen
A1  - Zaikin, Alexei
A1  - Kurths, Jürgen
A1  - Hege, H. C.
A1  - Gowin, W.
T1  - Quantification of spatial structure of human proximal tibial bone biopsies using 3D measures of complexity
N2  - Changes in trabecular bone composition during development of osteoporosis are used as a model for bone loss in microgravity conditions during a space flight. Symbolic dynamics and measures of complexity are proposed and applied to assess quantitatively the structural composition of bone tissue from 3D data sets of human tibia bone biopsies acquired by a micro-CT scanner. In order to justify the newly proposed approach, the measures of complexity of the bone architecture were compared with the results of traditional 2D bone histomorphometry. The proposed technique is able to quantify the structural loss of the bone tissue and may help to diagnose and to monitor changes in bone structure of patients on Earth as well as of the space-flying personnel. © 2005 Elsevier Ltd. All rights reserved
Y1  - 2005
SN  - 0094-5765
ER  - 
TY  - INPR
A1  - Kurths, Jürgen
A1  - Voss, A.
A1  - Witt, Annette
A1  - Saparin, P.
A1  - Kleiner, H. J.
A1  - Wessel, Niels
T1  - Quantitative analysis of heart rate variability
N2  - In the modern industrialized countries every year several hundred thousands of people die due to the sudden cardiac death. The individual risk for this sudden cardiac death cannot be defined precisely by common available, non-invasive diagnostic tools like Holter-monitoring, highly amplified ECG and traditional linear analysis of heart rate variability (HRV). Therefore, we apply some rather unconventional methods of nonlinear dynamics to analyse the HRV. Especially, some complexity measures that are basing on symbolic dynamics as well as a new measure, the renormalized entropy, detect some abnormalities in the HRV of several patients who have been classified in the low risk group by traditional methods. A combination of these complexity measures with the parameters in the frequency domain seems to be a promising way to get a more precise definition of the individual risk. These findings have to be validated by a representative number of patients.
T3  - NLD Preprints - 5 
Y1  - 1994
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-13470
ER  - 
TY  - JOUR
A1  - Saparin, Peter
A1  - Kurths, Jürgen
A1  - Gowin, P.
A1  - Felsenberg, D.
T1  - Die quantitative Beurteilung trabeculärer Knochenstrukturen der Lendenwirbelkörper durch Meßmethoden der nicht-linearen Dynamik
Y1  - 1997
ER  - 
TY  - JOUR
A1  - Kopitzki, K.
A1  - Warnke, P. C.
A1  - Saparin, Peter
A1  - Kurths, Jürgen
A1  - Timmer, Jens
T1  - Comment on "Kullback-Leibler and renormalized entropies: Applications to electroencephalograms of epilepsy patients"
Y1  - 2002
ER  -