TY  - JOUR
A1  - Koenig, Julian
A1  - Abler, Birgit
A1  - Agartz, Ingrid
A1  - akerstedt, Torbjorn
A1  - Andreassen, Ole A.
A1  - Anthony, Mia
A1  - Baer, Karl-Juergen
A1  - Bertsch, Katja
A1  - Brown, Rebecca C.
A1  - Brunner, Romuald
A1  - Carnevali, Luca
A1  - Critchley, Hugo D.
A1  - Cullen, Kathryn R.
A1  - de Geus, Eco J. C.
A1  - de la Cruz, Feliberto
A1  - Dziobek, Isabel
A1  - Ferger, Marc D.
A1  - Fischer, Hakan
A1  - Flor, Herta
A1  - Gaebler, Michael
A1  - Gianaros, Peter J.
A1  - Giummarra, Melita J.
A1  - Greening, Steven G.
A1  - Guendelman, Simon
A1  - Heathers, James A. J.
A1  - Herpertz, Sabine C.
A1  - Hu, Mandy X.
A1  - Jentschke, Sebastian
A1  - Kaess, Michael
A1  - Kaufmann, Tobias
A1  - Klimes-Dougan, Bonnie
A1  - Koelsch, Stefan
A1  - Krauch, Marlene
A1  - Kumral, Deniz
A1  - Lamers, Femke
A1  - Lee, Tae-Ho
A1  - Lekander, Mats
A1  - Lin, Feng
A1  - Lotze, Martin
A1  - Makovac, Elena
A1  - Mancini, Matteo
A1  - Mancke, Falk
A1  - Mansson, Kristoffer N. T.
A1  - Manuck, Stephen B.
A1  - Mather, Mara
A1  - Meeten, Frances
A1  - Min, Jungwon
A1  - Mueller, Bryon
A1  - Muench, Vera
A1  - Nees, Frauke
A1  - Nga, Lin
A1  - Nilsonne, Gustav
A1  - Ordonez Acuna, Daniela
A1  - Osnes, Berge
A1  - Ottaviani, Cristina
A1  - Penninx, Brenda W. J. H.
A1  - Ponzio, Allison
A1  - Poudel, Govinda R.
A1  - Reinelt, Janis
A1  - Ren, Ping
A1  - Sakaki, Michiko
A1  - Schumann, Andy
A1  - Sorensen, Lin
A1  - Specht, Karsten
A1  - Straub, Joana
A1  - Tamm, Sandra
A1  - Thai, Michelle
A1  - Thayer, Julian F.
A1  - Ubani, Benjamin
A1  - van Der Mee, Denise J.
A1  - van Velzen, Laura S.
A1  - Ventura-Bort, Carlos
A1  - Villringer, Arno
A1  - Watson, David R.
A1  - Wei, Luqing
A1  - Wendt, Julia
A1  - Schreiner, Melinda Westlund
A1  - Westlye, Lars T.
A1  - Weymar, Mathias
A1  - Winkelmann, Tobias
A1  - Wu, Guo-Rong
A1  - Yoo, Hyun Joo
A1  - Quintana, Daniel S.
T1  - Cortical thickness and resting-state cardiac function across the lifespan
BT  - a cross-sectional pooled mega-analysis
JF  - Psychophysiology : journal of the Society for Psychophysiological Research
N2  - Understanding the association between autonomic nervous system [ANS] function and brain morphology across the lifespan provides important insights into neurovisceral mechanisms underlying health and disease. Resting-state ANS activity, indexed by measures of heart rate [HR] and its variability [HRV] has been associated with brain morphology, particularly cortical thickness [CT]. While findings have been mixed regarding the anatomical distribution and direction of the associations, these inconsistencies may be due to sex and age differences in HR/HRV and CT. Previous studies have been limited by small sample sizes, which impede the assessment of sex differences and aging effects on the association between ANS function and CT. To overcome these limitations, 20 groups worldwide contributed data collected under similar protocols of CT assessment and HR/HRV recording to be pooled in a mega-analysis (N = 1,218 (50.5% female), mean age 36.7 years (range: 12-87)). Findings suggest a decline in HRV as well as CT with increasing age. CT, particularly in the orbitofrontal cortex, explained additional variance in HRV, beyond the effects of aging. This pattern of results may suggest that the decline in HRV with increasing age is related to a decline in orbitofrontal CT. These effects were independent of sex and specific to HRV; with no significant association between CT and HR. Greater CT across the adult lifespan may be vital for the maintenance of healthy cardiac regulation via the ANS-or greater cardiac vagal activity as indirectly reflected in HRV may slow brain atrophy. Findings reveal an important association between CT and cardiac parasympathetic activity with implications for healthy aging and longevity that should be studied further in longitudinal research.
KW  - aging
KW  - autonomic nervous system
KW  - cortical thickness
KW  - heart rate
KW  - heart
KW  - rate variability
KW  - sex
Y1  - 2020
U6  - https://doi.org/10.1111/psyp.13688
SN  - 0048-5772
SN  - 1469-8986
VL  - 58
IS  - 7
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Brown, Lauren E.
A1  - Landaverry, Yakira R.
A1  - Davies, James R.
A1  - Milinkevich, Kristin A.
A1  - Ast, Sandra
A1  - Carlson, Joseph S.
A1  - Oliver, Allen G.
A1  - Konopelski, Joseph P.
T1  - Progress toward the total synthesis of Psymberin/Irciniastatin A
N2  - In this paper, we describe our synthesis of four key building blocks for the total synthesis of psymberin (1) and its C4 epimer (2). Despite early difficulties in processing material to the advanced intermediate stage, we have been successful in developing high-yielding syntheses for the pyran core, natural side chain, 4-epi side chain, and aryl fragments of the molecule. Our findings from the optimization process are presented herein.
Y1  - 2009
UR  - http://pubs.acs.org/journal/joceah
U6  - https://doi.org/10.1021/Jo9009003
SN  - 0022-3263
ER  - 
TY  - CHAP
A1  - Jacqmin, Julien
A1  - Özdemir, Paker Doğu
A1  - Fell Kurban, Caroline
A1  - Tunç Pekkan, Zelha
A1  - Koskinen, Johanna
A1  - Suonpää, Maija
A1  - Seng, Cheyvuth
A1  - Carlon, May Kristine Jonson
A1  - Gayed, John Maurice
A1  - Cross, Jeffrey S.
A1  - Langseth, Inger
A1  - Jacobsen, Dan Yngve
A1  - Haugsbakken, Halvdan
A1  - Bethge, Joseph
A1  - Serth, Sebastian
A1  - Staubitz, Thomas
A1  - Wuttke, Tobias
A1  - Nordemann, Oliver
A1  - Das, Partha-Pratim
A1  - Meinel, Christoph
A1  - Ponce, Eva
A1  - Srinath, Sindhu
A1  - Allegue, Laura
A1  - Perach, Shai
A1  - Alexandron, Giora
A1  - Corti, Paola
A1  - Baudo, Valeria
A1  - Turró, Carlos
A1  - Moura Santos, Ana
A1  - Nilsson, Charlotta
A1  - Maldonado-Mahauad, Jorge
A1  - Valdiviezo, Javier
A1  - Carvallo, Juan Pablo
A1  - Samaniego-Erazo, Nicolay
A1  - Poce, Antonella
A1  - Re, Maria Rosaria
A1  - Valente, Mara
A1  - Karp Gershon, Sa’ar
A1  - Ruipérez-Valiente, José A.
A1  - Despujol, Ignacio
A1  - Busquets, Jaime
A1  - Kerr, John
A1  - Lorenz, Anja
A1  - Schön, Sandra
A1  - Ebner, Martin
A1  - Wittke, Andreas
A1  - Beirne, Elaine
A1  - Nic Giolla Mhichíl, Mairéad
A1  - Brown, Mark
A1  - Mac Lochlainn, Conchúr
A1  - Topali, Paraskevi
A1  - Chounta, Irene-Angelica
A1  - Ortega-Arranz, Alejandro
A1  - Villagrá-Sobrino, Sara L.
A1  - Martínez-Monés, Alejandra
A1  - Blackwell, Virginia Katherine
A1  - Wiltrout, Mary Ellen
A1  - Rami Gaddem, Mohamed
A1  - Hernández Reyes, César Augusto
A1  - Nagahama, Toru
A1  - Buchem, Ilona
A1  - Okatan, Ebru
A1  - Khalil, Mohammad
A1  - Casiraghi, Daniela
A1  - Sancassani, Susanna
A1  - Brambilla, Federica
A1  - Mihaescu, Vlad
A1  - Andone, Diana
A1  - Vasiu, Radu
A1  - Şahin, Muhittin
A1  - Egloffstein, Marc
A1  - Bothe, Max
A1  - Rohloff, Tobias
A1  - Schenk, Nathanael
A1  - Schwerer, Florian
A1  - Ifenthaler, Dirk
A1  - Hense, Julia
A1  - Bernd, Mike
ED  - Meinel, Christoph
ED  - Staubitz, Thomas
ED  - Schweiger, Stefanie
ED  - Friedl, Christian
ED  - Kiers, Janine
ED  - Ebner, Martin
ED  - Lorenz, Anja
ED  - Ubachs, George
ED  - Mongenet, Catherine
ED  - Ruipérez-Valiente, José A.
ED  - Cortes Mendez, Manoel
T1  - EMOOCs 2021
N2  - From June 22 to June 24, 2021, Hasso Plattner Institute, Potsdam, hosted the seventh European MOOC Stakeholder Summit (EMOOCs 2021) together with the eighth ACM Learning@Scale Conference.
Due to the COVID-19 situation, the conference was held fully online.
The boost in digital education worldwide as a result of the pandemic was also one of the main topics of this year’s EMOOCs. All institutions of learning have been forced to transform and redesign their educational methods, moving from traditional models to hybrid or completely online models at scale. The learnings, derived from practical experience and research, have been explored in EMOOCs 2021 in six tracks and additional workshops, covering various aspects of this field. In this publication, we present papers from the conference’s Experience Track, the Policy Track, the Business Track, the International Track, and the Workshops.
KW  - e-learning
KW  - microcredential
KW  - MOOC
KW  - digital education
KW  - experience
KW  - online course design
KW  - online course creation
KW  - higher education
Y1  - 2021
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-510300
SN  - 978-3-86956-512-5
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Hund, Silja V.
A1  - Brown, Sandra
A1  - Lavkulich, Les M.
A1  - Oswald, Sascha
T1  - Relating P Lability in Stream Sediments to Watershed Land Use via an Effective Sequential Extraction Scheme
JF  - Water, air & soil pollution : an international journal of environmental pollution
N2  - High applications of P fertilizers and manure are general practice in intensive agriculture and may cause eutrophication in adjacent streams. Bioavailability of P can be estimated by sequential extractions commonly used for soil or sediment. A single combined method may facilitate more effective comparisons of topsoils and adjoining stream sediments, and enhance management decisions. In this study, the suitability of an established soil P sequential extraction was tested on stream bed sediments. The study was conducted in the Sumas River watershed in the agricultural Lower Fraser Valley, Canada. Sediment samples with differing land use (forest, low and high intensity agriculture) from 1993, 1994, 2008, and 2009 from 14 sites along the Sumas River and tributaries were used. Total sequential extraction concentrations were in agreement with aqua regia digestion (Rs=0.96) and showed consistency over the study time sequence. P fractions released by 0.5 M NaHCO3 (median 14 %), 0.1 M NaOH (33 %), and 1.0 M HCl (38 %) were significantly (alpha=0.05) higher than P released by other extractants. These three extraction steps provide a practical and time-effective assessment of P lability in stream sediments and may be used as a combined scheme for sediment and soil. Analytical results further revealed that land use has a major and characteristic impact on P lability. With a land use change from forest to intensive agriculture, results showed an increase in total P concentrations (30 to 4,000 ppm) and in P lability, in particular for the moderately labile NaOH-P fraction (20 to 50 %).
KW  - Phosphorus
KW  - Eutrophication
KW  - Availability
KW  - Sequential extraction
KW  - Agriculture
KW  - River bed sediment
Y1  - 2013
U6  - https://doi.org/10.1007/s11270-013-1643-9
SN  - 0049-6979
SN  - 1573-2932
VL  - 224
IS  - 9
PB  - Springer
CY  - Dordrecht
ER  -