TY - JOUR A1 - Salleh, Faezah Mohd A1 - Ramos-Madrigal, Jazmin A1 - Penaloza, Fernando A1 - Liu, Shanlin A1 - Sinding, Mikkel-Holger S. A1 - Patel, Riddhi P. A1 - Martins, Renata A1 - Lenz, Dorina A1 - Fickel, Jörns A1 - Roos, Christian A1 - Shamsir, Mohd Shahir A1 - Azman, Mohammad Shahfiz A1 - Lim, Burton K. A1 - Rossiter, Stephen J. A1 - Wilting, Andreas A1 - Gilbert, M. Thomas P. T1 - An expanded mammal mitogenome dataset from Southeast Asia JF - Gigascience N2 - Background: Findings: Approximately 55 gigabases of raw sequence were generated. From this data we assembled 72 complete mitogenome sequences, with an average depth of coverage of 102.9x and 55.2x for modern samples and historical samples, respectively. This dataset represents 52 species, of which 30 species had no previous mitogenome data available. The mitogenomes were geotagged to their sampling location, where known, to display a detailed geographical distribution of the species. Conclusion: KW - invertebrate-derived (iDNA) KW - metabarcoding KW - GenBank KW - Taxonomic assignment Y1 - 2017 SN - 2047-217X VL - 6 IS - 8 SP - 1 EP - 19 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Barnett, Ross A1 - Westbury, Michael V. A1 - Sandoval-Velasco, Marcela A1 - Vieira, Filipe Garrett A1 - Jeon, Sungwon A1 - Zazula, Grant A1 - Martin, Michael D. A1 - Ho, Simon Y. W. A1 - Mather, Niklas A1 - Gopalakrishnan, Shyam A1 - Ramos-Madrigal, Jazmin A1 - de Manuel, Marc A1 - Zepeda-Mendoza, M. Lisandra A1 - Antunes, Agostinho A1 - Baez, Aldo Carmona A1 - De Cahsan, Binia A1 - Larson, Greger A1 - O'Brien, Stephen J. A1 - Eizirik, Eduardo A1 - Johnson, Warren E. A1 - Koepfli, Klaus-Peter A1 - Wilting, Andreas A1 - Fickel, Jörns A1 - Dalen, Love A1 - Lorenzen, Eline D. A1 - Marques-Bonet, Tomas A1 - Hansen, Anders J. A1 - Zhang, Guojie A1 - Bhak, Jong A1 - Yamaguchi, Nobuyuki A1 - Gilbert, M. Thomas P. T1 - Genomic adaptations and evolutionary history of the extinct scimitar-toothed cat BT - Homotherium latidens JF - Current biology N2 - Homotherium was a genus of large-bodied scimitar-toothed cats, morphologically distinct from any extant felid species, that went extinct at the end of the Pleistocene [1-4]. They possessed large, saber-form serrated canine teeth, powerful forelimbs, a sloping back, and an enlarged optic bulb, all of which were key characteristics for predation on Pleistocene megafauna [5]. Previous mitochondrial DNA phylogenies suggested that it was a highly divergent sister lineage to all extant cat species [6-8]. However, mitochondrial phylogenies can be misled by hybridization [9], incomplete lineage sorting (ILS), or sex-biased dispersal patterns [10], which might be especially relevant for Homotherium since widespread mito-nuclear discrepancies have been uncovered in modern cats [10]. To examine the evolutionary history of Homotherium, we generated a -7x nuclear genome and a similar to 38x exome from H. latidens using shotgun and target-capture sequencing approaches. Phylogenetic analyses reveal Homotherium as highly divergent (similar to 22.5 Ma) from living cat species, with no detectable signs of gene flow. Comparative genomic analyses found signatures of positive selection in several genes, including those involved in vision, cognitive function, and energy consumption, putatively consistent with diurnal activity, well-developed social behavior, and cursorial hunting [5]. Finally, we uncover relatively high levels of genetic diversity, suggesting that Homotherium may have been more abundant than the limited fossil record suggests [3, 4, 11-14]. Our findings complement and extend previous inferences from both the fossil record and initial molecular studies, enhancing our understanding of the evolution and ecology of this remarkable lineage. Y1 - 2020 U6 - https://doi.org/10.1016/j.cub.2020.09.051 SN - 0960-9822 SN - 1879-0445 VL - 30 IS - 24 PB - Cell Press CY - Cambridge ER -