TY  - JOUR
A1  - Li, Jian
A1  - Lu, Yong-Ping
A1  - Tsuprykov, Oleg
A1  - Hasan, Ahmed Abdallah Abdalrahman Mohamed
A1  - Reichetzeder, Christoph
A1  - Tian, Mei
A1  - Zhang, Xiao Li
A1  - Zhang, Qin
A1  - Sun, Guo-Ying
A1  - Guo, Jingli
A1  - Gaballa, Mohamed Mahmoud Salem Ahmed
A1  - Peng, Xiao-Ning
A1  - Lin, Ge
A1  - Hocher, Berthold
T1  - Folate treatment of pregnant rat dams abolishes metabolic effects in female offspring induced by a paternal pre-conception unhealthy diet
JF  - Diabetologia : journal of the European Association for the Study of Diabetes (EASD)
N2  - Aims/hypothesis Paternal high-fat diet prior to mating programmes impaired glucose tolerance in female offspring. We examined whether the metabolic consequences in offspring could be abolished by folate treatment of either the male rats before mating or the corresponding female rats during pregnancy. Methods Male F0 rats were fed either control diet or high-fat, high-sucrose and high-salt diet (HFSSD), with or without folate, before mating. Male rats were mated with control-diet-fed dams. After mating, the F0 dams were fed control diet with or without folate during pregnancy.
KW  - Glucose tolerance
KW  - High-fat-sucrose-salt diet
KW  - Maternal folate treatment
KW  - Paternal programming
Y1  - 2018
U6  - https://doi.org/10.1007/s00125-018-4635-x
SN  - 0012-186X
SN  - 1432-0428
VL  - 61
IS  - 8
SP  - 1862
EP  - 1876
PB  - Springer
CY  - New York
ER  - 
TY  - JOUR
A1  - Tian, Fang
A1  - Qin, Wen
A1  - Zhang, Ran
A1  - Herzschuh, Ulrike
A1  - Ni, Jian
A1  - Zhang, Chengjun
A1  - Mischke, Steffen
A1  - Cao, Xianyong
T1  - Palynological evidence for the temporal stability of the plant community in the Yellow River Source Area over the last 7,400 years
JF  - Vegetation history and archaeobotany
N2  - The terrestrial ecosystem in the Yellow River Source Area (YRSA) is sensitive to climate change and human impacts, although past vegetation change and the degree of human disturbance are still largely unknown. A 170-cm-long sediment core covering the last 7,400 years was collected from Lake Xingxinghai (XXH) in the YRSA. Pollen, together with a series of other environmental proxies (including grain size, total organic carbon (TOC) and carbonate content), were analysed to explore past vegetation and environmental changes for the YRSA. Dominant and common pollen components-Cyperaceae, Poaceae, Artemisia, Chenopodiaceae and Asteraceae-are stable throughout the last 7,400 years. Slight vegetation change is inferred from an increasing trend of Cyperaceae and decreasing trend of Poaceae, suggesting that alpine steppe was replaced by alpine meadow at ca. 3.5 ka cal bp. The vegetation transformation indicates a generally wetter climate during the middle and late Holocene, which is supported by increased amounts of TOC and Pediastrum (representing high water-level) and is consistent with previous past climate records from the north-eastern Tibetan Plateau. Our results find no evidence of human impact on the regional vegetation surrounding XXH, hence we conclude the vegetation change likely reflects the regional climate signal.
KW  - Pollen
KW  - Lake Xingxinghai
KW  - Tibetan Plateau
KW  - Holocene
KW  - Vegetation change
KW  - Regional climate
Y1  - 2022
U6  - https://doi.org/10.1007/s00334-022-00870-5
SN  - 0939-6314
SN  - 1617-6278
VL  - 31
IS  - 6
SP  - 549
EP  - 558
PB  - Springer
CY  - New York
ER  - 
TY  - JOUR
A1  - Li, Jian
A1  - Shen, Jinhua
A1  - Zhang, Xiaoli
A1  - Peng, Yangqin
A1  - Zhang, Qin
A1  - Hu, Liang
A1  - Reichetzeder, Christoph
A1  - Zeng, Suimin
A1  - Li, Jing
A1  - Tian, Mei
A1  - Gong, Fei
A1  - Lin, Ge
A1  - Hocher, Berthold
T1  - Risk factors associated with preterm birth after IVF/ICSI
JF  - Scientific reports
N2  - In vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) is associated with an increased risk of preterm (33rd-37th gestational week) and early preterm birth (20th-32nd gestational week). The underlying general and procedure related risk factors are not well understood so far. 4328 infertile women undergoing IVF/ICSI were entered into this study. The study population was divided into three groups: (a) early preterm birth group (n = 66), (b) preterm birth group (n = 675) and (c) full-term birth group (n = 3653). Odds for preterm birth were calculated by stepwise multivariate logistic regression analysis. We identified seven independent risk factors for preterm birth and four independent risk factors for early preterm birth. Older (> 39) or younger (< 25) maternal age (OR: 1.504, 95% CI 1.108-2.042, P = 0.009; OR: 2.125, 95% CI 1.049-4.304, P = 0.036, respectively), multiple pregnancy (OR: 9.780, 95% CI 8.014-11.935, P < 0.001; OR: 8.588, 95% CI 4.866-15.157, P < 0.001, respectively), placenta previa (OR: 14.954, 95% CI 8.053-27.767, P < 0.001; OR: 16.479, 95% CI 4.381-61.976, P < 0.001, respectively), and embryo reduction (OR: 3.547, 95% CI 1.736-7.249, P = 0.001; OR: 7.145, 95% CI 1.990-25.663, P = 0.003, respectively) were associated with preterm birth and early preterm birth, whereas gestational hypertension (OR: 2.494, 95% CI 1.770-3.514, P < 0.001), elevated triglycerides (OR: 1.120, 95% CI 1.011-1.240, P = 0.030) and shorter activated partial thromboplastin time (OR: 0.967, 95% CI 0.949-0.985, P < 0.001) were associated only with preterm birth. In conclusion, preterm and early preterm birth risk factors in patients undergoing assisted IVF/ICSI are in general similar to those in natural pregnancy. The lack of some associations in the early preterm group was most likely due to the lower number of early preterm birth cases. Only embryo reduction represents an IVF/ICSI specific risk factor.
Y1  - 2022
U6  - https://doi.org/10.1038/s41598-022-12149-w
SN  - 2045-2322
VL  - 12
IS  - 1
PB  - Nature Research
CY  - Berlin
ER  -