TY  - JOUR
A1  - Günther, Oliver
A1  - Zimmermann, Matthias
A1  - Kampe, Heike
A1  - Scholz, Jana
A1  - Eckardt, Barbara
A1  - Schmidt, Anna Theresa
A1  - Görlich, Petra
A1  - Lux, Nadine
A1  - Szameitat, Ulrike
A1  - Ziemer, Franziska
A1  - Jäger, Heidi
A1  - Rost, Sophia
T1  - Portal = Konzepte und Visionen: Städte der Zukunft
BT  - Das Potsdamer Universitätsmagazin
N2  - Aus dem Inhalt:
- Konzepte und Visionen: Städte der Zukunft
- Uni plant Entwicklung bis 2018
- Was glänzt und was fehlt
T3  - Portal: Das Potsdamer Universitätsmagazin - 01/2015 
Y1  - 2015
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-440624
SN  - 1618-6893
IS  - 01/2015
ER  - 
TY  - CHAP
A1  - Kurbel, Karl
A1  - Nowak, Dawid
A1  - Azodi, Amir
A1  - Jaeger, David
A1  - Meinel, Christoph
A1  - Cheng, Feng
A1  - Sapegin, Andrey
A1  - Gawron, Marian
A1  - Morelli, Frank
A1  - Stahl, Lukas
A1  - Kerl, Stefan
A1  - Janz, Mariska
A1  - Hadaya, Abdulmasih
A1  - Ivanov, Ivaylo
A1  - Wiese, Lena
A1  - Neves, Mariana
A1  - Schapranow, Matthieu-Patrick
A1  - Fähnrich, Cindy
A1  - Feinbube, Frank
A1  - Eberhardt, Felix
A1  - Hagen, Wieland
A1  - Plauth, Max
A1  - Herscheid, Lena
A1  - Polze, Andreas
A1  - Barkowsky, Matthias
A1  - Dinger, Henriette
A1  - Faber, Lukas
A1  - Montenegro, Felix
A1  - Czachórski, Tadeusz
A1  - Nycz, Monika
A1  - Nycz, Tomasz
A1  - Baader, Galina
A1  - Besner, Veronika
A1  - Hecht, Sonja
A1  - Schermann, Michael
A1  - Krcmar, Helmut
A1  - Wiradarma, Timur Pratama
A1  - Hentschel, Christian
A1  - Sack, Harald
A1  - Abramowicz, Witold
A1  - Sokolowska, Wioletta
A1  - Hossa, Tymoteusz
A1  - Opalka, Jakub
A1  - Fabisz, Karol
A1  - Kubaczyk, Mateusz
A1  - Cmil, Milena
A1  - Meng, Tianhui
A1  - Dadashnia, Sharam
A1  - Niesen, Tim
A1  - Fettke, Peter
A1  - Loos, Peter
A1  - Perscheid, Cindy
A1  - Schwarz, Christian
A1  - Schmidt, Christopher
A1  - Scholz, Matthias
A1  - Bock, Nikolai
A1  - Piller, Gunther
A1  - Böhm, Klaus
A1  - Norkus, Oliver
A1  - Clark, Brian
A1  - Friedrich, Björn
A1  - Izadpanah, Babak
A1  - Merkel, Florian
A1  - Schweer, Ilias
A1  - Zimak, Alexander
A1  - Sauer, Jürgen
A1  - Fabian, Benjamin
A1  - Tilch, Georg
A1  - Müller, David
A1  - Plöger, Sabrina
A1  - Friedrich, Christoph M.
A1  - Engels, Christoph
A1  - Amirkhanyan, Aragats
A1  - van der Walt, Estée
A1  - Eloff, J. H. P.
A1  - Scheuermann, Bernd
A1  - Weinknecht, Elisa
ED  - Meinel, Christoph
ED  - Polze, Andreas
ED  - Oswald, Gerhard
ED  - Strotmann, Rolf
ED  - Seibold, Ulrich
ED  - Schulzki, Bernhard
T1  - HPI Future SOC Lab
BT  - Proceedings 2015
N2  - Das Future SOC Lab am HPI ist eine Kooperation des Hasso-Plattner-Instituts mit verschiedenen Industriepartnern. Seine Aufgabe ist die Ermöglichung und Förderung des Austausches zwischen Forschungsgemeinschaft und Industrie.
Am Lab wird interessierten Wissenschaftlern eine Infrastruktur von neuester Hard- und Software kostenfrei für Forschungszwecke zur Verfügung gestellt. Dazu zählen teilweise noch nicht am Markt verfügbare Technologien, die im normalen Hochschulbereich in der Regel nicht zu finanzieren wären, bspw. Server mit bis zu 64 Cores und 2 TB Hauptspeicher. Diese Angebote richten sich insbesondere an Wissenschaftler in den Gebieten Informatik und Wirtschaftsinformatik. Einige der Schwerpunkte sind Cloud Computing, Parallelisierung und In-Memory Technologien. 
In diesem Technischen Bericht werden die Ergebnisse der Forschungsprojekte des Jahres 2015 vorgestellt.  Ausgewählte Projekte stellten ihre Ergebnisse am 15. April 2015 und 4. November 2015 im Rahmen der Future SOC Lab Tag Veranstaltungen vor.
KW  - Future SOC Lab
KW  - Forschungsprojekte
KW  - Multicore Architekturen
KW  - In-Memory Technologie
KW  - Cloud Computing
KW  - maschinelles Lernen
KW  - künstliche Intelligenz
Y1  - 2017
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-102516
ER  - 
TY  - THES
A1  - Schmidt, Oliver
T1  - Gewalttätiger Protest im Vormärz
T1  - Violent protest in the time of Vormärz
BT  - Eine Erklärung aus historisch-soziologischer Perspektive
BT  - An historical and sociological approach
N2  - Historisch wie aktuell werden durch gewalttätige soziale Auseinandersetzungen bestehende gesellschaftliche Ordnungen infrage gestellt. In der Geschichtswissenschaft wie in der Soziologie waren Tumulte, Aufstände oder soziale Erhebungen immer wieder Gegenstand von Untersuchungen. Während der historische Zugriff auf diese Phänomene gewöhnlich durch detaillierte Beschreibungen historische Abläufe genau zu rekonstruieren versucht hat, um diese verstehen zu können, geht es soziologischen Arbeiten zumeist um einen viel stärker generalisierenden und erklärenden Zugriff. Zwar gab es immer wieder Anläufe, diese scheinbar unüberbrückbare Differenz zwischen den Disziplinen zu überwinden, doch alle die Versuche müssen als mehr oder weniger gescheitert angesehen werden. Nach wie vor gilt deshalb, dass mit der ausschließlichen Konzentration auf die je eigene disziplinäre Herangehensweise viel Erkenntnispotenzial verschenkt wird. Aus diesem Grund unterbreitet die vorliegende Studie einen neuen Vorschlag, Geschichtswissenschaft und Soziologie zusammenzubringen. Der Verfasser unternimmt hier den Versuch, die beiden vermeintlich so gegensätzlichen Auffassungen von Wissenschaftlichkeit über eine gemeinsame methodologische Perspektive zusammenzuführen und auf dieser Grundlage einen vereinten, erklärenden Zugriff von Geschichtswissenschaft und Soziologie zu skizzieren, der nach dem „Wie“ eines Ereignisses fragt, zugleich aber auch erklären will, „warum“ es dazu gekommen ist. Das vorliegende Buch untersucht auf dieser methodologischen Grundlage und mittels eines historisch-soziologischen Zugangs sozialen Protest im Vormärz, es schließt an Arbeiten der historischen Soziologie und Sozialgeschichte an und entwickelt dazu einen stringenten historisch-soziologischen Erklärungsansatz.
N2  - In history but also in the present - social orders were challenged by violent conflicts. The science of history and sociology have investigated the phenomenons of disturbance, rebellion and social revolts. Whereas the historical account of these phenomenons is mainly characterized by the reconstruction of detailed descriptions of the historical processes and events, sociological surveys seek to discover a more generalizing explanation. Over the last years numerous attempts have been made to overcome the discrepancies between the two disciplines, unsuccessfully though. Scientific research is still lacking, for focusing on only one discipline would lead to a waste of potential in terms of findings. This study aims at formulating a new scientific proposal that brings together the science of history and sociology. In the process, the author will bring the two sciences in conversation with each other. A common methodological approach is the basis for a socio-historical explanation which shows the “how” of an event and, at the same time, “why” such events have happened. This book focuses on social protest at the time of ‘Vormärz’ and aims at developing a compelling explanation through a methodological approach that takes into account both the historical and the sociological discourse.
T3  - Soziologische Theorie und Organization Studies - 1 
KW  - Protest
KW  - Methodologie
KW  - Soziologie
KW  - Sozialgeschichte
KW  - Vormärz
Y1  - 2014
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-72253
SN  - 978-3-86956-310-7
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Schmidt, Anna
A1  - Eckardt, Barbara
A1  - Marszałek, Magdalena
A1  - Görlich, Petra
A1  - Bieber, Sabine
A1  - Kampe, Heike
A1  - Jäger, Sophie
A1  - Horn-Conrad, Antje
A1  - Günther, Oliver
A1  - Seckler, Robert
A1  - Seppä, Silvana
A1  - Guske, Katja
A1  - Szameitat, Ulrike
A1  - Bezzenberger, Tilman
A1  - Sütterlin, Sabine
A1  - Weller, Nina
A1  - Klauke, Lars
T1  - Portal = Sommer an der Uni: Leere Hörsäle? Volle Terminkalender!
BT  - Das Potsdamer Universitätsmagazin
N2  - Aus dem Inhalt:
- Sommer an der Uni: Leere Hörsäle? Volle Terminkalender!
- Stärken stärken
- Unter Stress
T3  - Portal: Das Potsdamer Universitätsmagazin - 03/2014 
Y1  - 2014
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-443021
IS  - 03/2014
ER  - 
TY  - JOUR
A1  - Schmidt, Bernd
A1  - Kunz, Oliver
T1  - Stereoselective synthesis of dienyl phosphonates via extended tethered ring-closing metathesis
JF  - Organic letters
N2  - Allylphosphonates of allylic alcohols were converted to conjugated dienyl phosphonates in a one-flask reaction, comprising a ring-closing metathesis (RCM), a base-induced ring-opening, and an alkylation. The ring-opening proceeds with very high diastereoselectivity, giving exclusively the (1Z,3E)-configured dienes. Single diastereomers and mixtures of diastereomers can be used as starting materials without noticeable effect on the diastereoselectivity of the sequence.
Y1  - 2013
U6  - https://doi.org/10.1021/ol4020078
SN  - 1523-7060
SN  - 1523-7052
VL  - 15
IS  - 17
SP  - 4470
EP  - 4473
PB  - American Chemical Society
CY  - Washington
ER  - 
TY  - JOUR
A1  - Schmidt, Bernd
A1  - Kunz, Oliver
T1  - Bidirectional cross metathesis and ring-closing metathesis/ring opening of a C-2-symmetric building block: a strategy for the synthesis of decanolide natural products
JF  - Beilstein journal of organic chemistry
N2  - Starting from the conveniently available ex-chiral pool building block (R,R)-hexa-1,5-diene-3,4-diol, the ten-membered ring lactones stagonolide E and curvulide A were synthesized using a bidirectional olefin-metathesis functionalization of the terminal double bonds. Key steps are (i) a site-selective cross metathesis, (ii) a highly diastereoselective extended tethered RCM to furnish a (Z,E)-configured dienyl carboxylic acid and (iii) a Ru-lipase-catalyzed dynamic kinetic resolution to establish the desired configuration at C9. Ring closure was accomplished by macrolactonization. Curvulide A was synthesized from stagonolide E through Sharpless epoxidation.
KW  - dienes
KW  - enzyme catalysis
KW  - lactones
KW  - metathesis
KW  - natural products
KW  - ruthenium
Y1  - 2013
U6  - https://doi.org/10.3762/bjoc.9.289
SN  - 1860-5397
VL  - 9
SP  - 2544
EP  - 2555
PB  - Beilstein-Institut zur Förderung der Chemischen Wissenschaften
CY  - Frankfurt, Main
ER  - 
TY  - JOUR
A1  - Meyer, Rhonda C.
A1  - Witucka-Wall, Hanna
A1  - Becher, Martina
A1  - Blacha, Anna Maria
A1  - Boudichevskaia, Anastassia
A1  - Dörmann, Peter
A1  - Fiehn, Oliver
A1  - Friedel, Svetlana
A1  - von Korff, Maria
A1  - Lisec, Jan
A1  - Melzer, Michael
A1  - Repsilber, Dirk
A1  - Schmidt, Renate
A1  - Scholz, Matthias
A1  - Selbig, Joachim
A1  - Willmitzer, Lothar
A1  - Altmann, Thomas
T1  - Heterosis manifestation during early Arabidopsis seedling development is characterized by intermediate gene expression and enhanced metabolic activity in the hybrids
JF  - The plant journal
N2  - Heterosis-associated cellular and molecular processes were analyzed in seeds and seedlings of Arabidopsis thaliana accessions Col-0 and C24 and their heterotic hybrids. Microscopic examination revealed no advantages in terms of hybrid mature embryo organ sizes or cell numbers. Increased cotyledon sizes were detectable 4 days after sowing. Growth heterosis results from elevated cell sizes and numbers, and is well established at 10 days after sowing. The relative growth rates of hybrid seedlings were most enhanced between 3 and 4 days after sowing. Global metabolite profiling and targeted fatty acid analysis revealed maternal inheritance patterns for a large proportion of metabolites in the very early stages. During developmental progression, the distribution shifts to dominant, intermediate and heterotic patterns, with most changes occurring between 4 and 6 days after sowing. The highest incidence of heterotic patterns coincides with establishment of size differences at 4 days after sowing. In contrast, overall transcript patterns at 4, 6 and 10 days after sowing are characterized by intermediate to dominant patterns, with parental transcript levels showing the largest differences. Overall, the results suggest that, during early developmental stages, intermediate gene expression and higher metabolic activity in the hybrids compared to the parents lead to better resource efficiency, and therefore enhanced performance in the hybrids.
KW  - heterosis
KW  - seedlings
KW  - metabolite profiling
KW  - transcript profiling
KW  - morphological analysis
KW  - Arabidopsis thaliana
KW  - biomass
Y1  - 2012
U6  - https://doi.org/10.1111/j.1365-313X.2012.05021.x
SN  - 0960-7412
VL  - 71
IS  - 4
SP  - 669
EP  - 683
PB  - Wiley-Blackwell
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Taal, H. Rob
A1  - St Pourcain, Beate
A1  - Thiering, Elisabeth
A1  - Das, Shikta
A1  - Mook-Kanamori, Dennis O.
A1  - Warrington, Nicole M.
A1  - Kaakinen, Marika
A1  - Kreiner-Moller, Eskil
A1  - Bradfield, Jonathan P.
A1  - Freathy, Rachel M.
A1  - Geller, Frank
A1  - Guxens, Monica
A1  - Cousminer, Diana L.
A1  - Kerkhof, Marjan
A1  - Timpson, Nicholas J.
A1  - Ikram, M. Arfan
A1  - Beilin, Lawrence J.
A1  - Bonnelykke, Klaus
A1  - Buxton, Jessica L.
A1  - Charoen, Pimphen
A1  - Chawes, Bo Lund Krogsgaard
A1  - Eriksson, Johan
A1  - Evans, David M.
A1  - Hofman, Albert
A1  - Kemp, John P.
A1  - Kim, Cecilia E.
A1  - Klopp, Norman
A1  - Lahti, Jari
A1  - Lye, Stephen J.
A1  - McMahon, George
A1  - Mentch, Frank D.
A1  - Mueller-Nurasyid, Martina
A1  - O'Reilly, Paul F.
A1  - Prokopenko, Inga
A1  - Rivadeneira, Fernando
A1  - Steegers, Eric A. P.
A1  - Sunyer, Jordi
A1  - Tiesler, Carla
A1  - Yaghootkar, Hanieh
A1  - Breteler, Monique M. B.
A1  - Debette, Stephanie
A1  - Fornage, Myriam
A1  - Gudnason, Vilmundur
A1  - Launer, Lenore J.
A1  - van der Lugt, Aad
A1  - Mosley, Thomas H.
A1  - Seshadri, Sudha
A1  - Smith, Albert V.
A1  - Vernooij, Meike W.
A1  - Blakemore, Alexandra I. F.
A1  - Chiavacci, Rosetta M.
A1  - Feenstra, Bjarke
A1  - Fernandez-Banet, Julio
A1  - Grant, Struan F. A.
A1  - Hartikainen, Anna-Liisa
A1  - van der Heijden, Albert J.
A1  - Iniguez, Carmen
A1  - Lathrop, Mark
A1  - McArdle, Wendy L.
A1  - Molgaard, Anne
A1  - Newnham, John P.
A1  - Palmer, Lyle J.
A1  - Palotie, Aarno
A1  - Pouta, Annneli
A1  - Ring, Susan M.
A1  - Sovio, Ulla
A1  - Standl, Marie
A1  - Uitterlinden, Andre G.
A1  - Wichmann, H-Erich
A1  - Vissing, Nadja Hawwa
A1  - DeCarli, Charles
A1  - van Duijn, Cornelia M.
A1  - McCarthy, Mark I.
A1  - Koppelman, Gerard H.
A1  - Estivill, Xavier
A1  - Hattersley, Andrew T.
A1  - Melbye, Mads
A1  - Bisgaard, Hans
A1  - Pennell, Craig E.
A1  - Widen, Elisabeth
A1  - Hakonarson, Hakon
A1  - Smith, George Davey
A1  - Heinrich, Joachim
A1  - Jarvelin, Marjo-Riitta
A1  - Jaddoe, Vincent W. V.
A1  - Adair, Linda S.
A1  - Ang, Wei
A1  - Atalay, Mustafa
A1  - van Beijsterveldt, Toos
A1  - Bergen, Nienke
A1  - Benke, Kelly
A1  - Berry, Diane J.
A1  - Bradfield, Jonathan P.
A1  - Charoen, Pimphen
A1  - Coin, Lachlan
A1  - Cousminer, Diana L.
A1  - Das, Shikta
A1  - Davis, Oliver S. P.
A1  - Elliott, Paul
A1  - Evans, David M.
A1  - Feenstra, Bjarke
A1  - Flexeder, Claudia
A1  - Frayling, Tim
A1  - Freathy, Rachel M.
A1  - Gaillard, Romy
A1  - Geller, Frank
A1  - Groen-Blokhuis, Maria
A1  - Goh, Liang-Kee
A1  - Guxens, Monica
A1  - Haworth, Claire M. A.
A1  - Hadley, Dexter
A1  - Hebebrand, Johannes
A1  - Hinney, Anke
A1  - Hirschhorn, Joel N.
A1  - Holloway, John W.
A1  - Holst, Claus
A1  - Hottenga, Jouke Jan
A1  - Horikoshi, Momoko
A1  - Huikari, Ville
A1  - Hypponen, Elina
A1  - Iniguez, Carmen
A1  - Kaakinen, Marika
A1  - Kilpelainen, Tuomas O.
A1  - Kirin, Mirna
A1  - Kowgier, Matthew
A1  - Lakka, Hanna-Maaria
A1  - Lange, Leslie A.
A1  - Lawlor, Debbie A.
A1  - Lehtimaki, Terho
A1  - Lewin, Alex
A1  - Lindgren, Cecilia
A1  - Lindi, Virpi
A1  - Maggi, Reedik
A1  - Marsh, Julie
A1  - Middeldorp, Christel
A1  - Millwood, Iona
A1  - Mook-Kanamori, Dennis O.
A1  - Murray, Jeffrey C.
A1  - Nivard, Michel
A1  - Nohr, Ellen Aagaard
A1  - Ntalla, Ioanna
A1  - Oken, Emily
A1  - O'Reilly, Paul F.
A1  - Palmer, Lyle J.
A1  - Panoutsopoulou, Kalliope
A1  - Pararajasingham, Jennifer
A1  - Prokopenko, Inga
A1  - Rodriguez, Alina
A1  - Salem, Rany M.
A1  - Sebert, Sylvain
A1  - Siitonen, Niina
A1  - Sovio, Ulla
A1  - St Pourcain, Beate
A1  - Strachan, David P.
A1  - Sunyer, Jordi
A1  - Taal, H. Rob
A1  - Teo, Yik-Ying
A1  - Thiering, Elisabeth
A1  - Tiesler, Carla
A1  - Uitterlinden, Andre G.
A1  - Valcarcel, Beatriz
A1  - Warrington, Nicole M.
A1  - White, Scott
A1  - Willemsen, Gonneke
A1  - Yaghootkar, Hanieh
A1  - Zeggini, Eleftheria
A1  - Boomsma, Dorret I.
A1  - Cooper, Cyrus
A1  - Estivill, Xavier
A1  - Gillman, Matthew
A1  - Grant, Struan F. A.
A1  - Hakonarson, Hakon
A1  - Hattersley, Andrew T.
A1  - Heinrich, Joachim
A1  - Hocher, Berthold
A1  - Jaddoe, Vincent W. V.
A1  - Jarvelin, Marjo-Riitta
A1  - Lakka, Timo A.
A1  - McCarthy, Mark I.
A1  - Melbye, Mads
A1  - Mohlke, Karen L.
A1  - Dedoussis, George V.
A1  - Ong, Ken K.
A1  - Pearson, Ewan R.
A1  - Pennell, Craig E.
A1  - Price, Thomas S.
A1  - Power, Chris
A1  - Raitakari, Olli T.
A1  - Saw, Seang-Mei
A1  - Scherag, Andre
A1  - Simell, Olli
A1  - Sorensen, Thorkild I. A.
A1  - Timpson, Nicholas J.
A1  - Widen, Elisabeth
A1  - Wilson, James F.
A1  - Ang, Wei
A1  - van Beijsterveldt, Toos
A1  - Bergen, Nienke
A1  - Benke, Kelly
A1  - Berry, Diane J.
A1  - Bradfield, Jonathan P.
A1  - Charoen, Pimphen
A1  - Coin, Lachlan
A1  - Cousminer, Diana L.
A1  - Das, Shikta
A1  - Elliott, Paul
A1  - Evans, David M.
A1  - Frayling, Tim
A1  - Freathy, Rachel M.
A1  - Gaillard, Romy
A1  - Groen-Blokhuis, Maria
A1  - Guxens, Monica
A1  - Hadley, Dexter
A1  - Hottenga, Jouke Jan
A1  - Huikari, Ville
A1  - Hypponen, Elina
A1  - Kaakinen, Marika
A1  - Kowgier, Matthew
A1  - Lawlor, Debbie A.
A1  - Lewin, Alex
A1  - Lindgren, Cecilia
A1  - Marsh, Julie
A1  - Middeldorp, Christel
A1  - Millwood, Iona
A1  - Mook-Kanamori, Dennis O.
A1  - Nivard, Michel
A1  - O'Reilly, Paul F.
A1  - Palmer, Lyle J.
A1  - Prokopenko, Inga
A1  - Rodriguez, Alina
A1  - Sebert, Sylvain
A1  - Sovio, Ulla
A1  - St Pourcain, Beate
A1  - Standl, Marie
A1  - Strachan, David P.
A1  - Sunyer, Jordi
A1  - Taal, H. Rob
A1  - Thiering, Elisabeth
A1  - Tiesler, Carla
A1  - Uitterlinden, Andre G.
A1  - Valcarcel, Beatriz
A1  - Warrington, Nicole M.
A1  - White, Scott
A1  - Willemsen, Gonneke
A1  - Yaghootkar, Hanieh
A1  - Boomsma, Dorret I.
A1  - Estivill, Xavier
A1  - Grant, Struan F. A.
A1  - Hakonarson, Hakon
A1  - Hattersley, Andrew T.
A1  - Heinrich, Joachim
A1  - Jaddoe, Vincent W. V.
A1  - Jarvelin, Marjo-Riitta
A1  - McCarthy, Mark I.
A1  - Pennell, Craig E.
A1  - Power, Chris
A1  - Timpson, Nicholas J.
A1  - Widen, Elisabeth
A1  - Ikram, M. Arfan
A1  - Fornage, Myriam
A1  - Smith, Albert V.
A1  - Seshadri, Sudha
A1  - Schmidt, Reinhold
A1  - Debette, Stephanie
A1  - Vrooman, Henri A.
A1  - Sigurdsson, Sigurdur
A1  - Ropele, Stefan
A1  - Coker, Laura H.
A1  - Longstreth, W. T.
A1  - Niessen, Wiro J.
A1  - DeStefano, Anita L.
A1  - Beiser, Alexa
A1  - Zijdenbos, Alex P.
A1  - Struchalin, Maksim
A1  - Jack, Clifford R.
A1  - Nalls, Mike A.
A1  - Au, Rhoda
A1  - Hofman, Albert
A1  - Gudnason, Haukur
A1  - van der Lugt, Aad
A1  - Harris, Tamara B.
A1  - Meeks, William M.
A1  - Vernooij, Meike W.
A1  - van Buchem, Mark A.
A1  - Catellier, Diane
A1  - Gudnason, Vilmundur
A1  - Windham, B. Gwen
A1  - Wolf, Philip A.
A1  - van Duijn, Cornelia M.
A1  - Mosley, Thomas H.
A1  - Schmidt, Helena
A1  - Launer, Lenore J.
A1  - Breteler, Monique M. B.
A1  - DeCarli, Charles
T1  - Common variants at 12q15 and 12q24 are associated with infant head circumference
JF  - Nature genetics
N2  - To identify genetic variants associated with head circumference in infancy, we performed a meta-analysis of seven genome-wide association studies (GWAS) (N = 10,768 individuals of European ancestry enrolled in pregnancy and/or birth cohorts) and followed up three lead signals in six replication studies (combined N = 19,089). rs7980687 on chromosome 12q24 (P = 8.1 x 10(-9)) and rs1042725 on chromosome 12q15 (P = 2.8 x 10(-10)) were robustly associated with head circumference in infancy. Although these loci have previously been associated with adult height(1), their effects on infant head circumference were largely independent of height (P = 3.8 x 10(-7) for rs7980687 and P = 1.3 x 10(-7) for rs1042725 after adjustment for infant height). A third signal, rs11655470 on chromosome 17q21, showed suggestive evidence of association with head circumference (P = 3.9 x 10(-6)). SNPs correlated to the 17q21 signal have shown genome-wide association with adult intracranial volume(2), Parkinson's disease and other neurodegenerative diseases(3-5), indicating that a common genetic variant in this region might link early brain growth with neurological disease in later life.
Y1  - 2012
U6  - https://doi.org/10.1038/ng.2238
SN  - 1061-4036
VL  - 44
IS  - 5
SP  - 532
EP  - +
PB  - Nature Publ. Group
CY  - New York
ER  - 
TY  - JOUR
A1  - Ikram, M. Arfan
A1  - Fornage, Myriam
A1  - Smith, Albert V.
A1  - Seshadri, Sudha
A1  - Schmidt, Reinhold
A1  - Debette, Stephanie
A1  - Vrooman, Henri A.
A1  - Sigurdsson, Sigurdur
A1  - Ropele, Stefan
A1  - Taal, H. Rob
A1  - Mook-Kanamori, Dennis O.
A1  - Coker, Laura H.
A1  - Longstreth, W. T.
A1  - Niessen, Wiro J.
A1  - DeStefano, Anita L.
A1  - Beiser, Alexa
A1  - Zijdenbos, Alex P.
A1  - Struchalin, Maksim
A1  - Jack, Clifford R.
A1  - Rivadeneira, Fernando
A1  - Uitterlinden, Andre G.
A1  - Knopman, David S.
A1  - Hartikainen, Anna-Liisa
A1  - Pennell, Craig E.
A1  - Thiering, Elisabeth
A1  - Steegers, Eric A. P.
A1  - Hakonarson, Hakon
A1  - Heinrich, Joachim
A1  - Palmer, Lyle J.
A1  - Jarvelin, Marjo-Riitta
A1  - McCarthy, Mark I.
A1  - Grant, Struan F. A.
A1  - St Pourcain, Beate
A1  - Timpson, Nicholas J.
A1  - Smith, George Davey
A1  - Sovio, Ulla
A1  - Nalls, Mike A.
A1  - Au, Rhoda
A1  - Hofman, Albert
A1  - Gudnason, Haukur
A1  - van der Lugt, Aad
A1  - Harris, Tamara B.
A1  - Meeks, William M.
A1  - Vernooij, Meike W.
A1  - van Buchem, Mark A.
A1  - Catellier, Diane
A1  - Jaddoe, Vincent W. V.
A1  - Gudnason, Vilmundur
A1  - Windham, B. Gwen
A1  - Wolf, Philip A.
A1  - van Duijn, Cornelia M.
A1  - Mosley, Thomas H.
A1  - Schmidt, Helena
A1  - Launer, Lenore J.
A1  - Breteler, Monique M. B.
A1  - DeCarli, Charles
A1  - Adair, Linda S.
A1  - Ang, Wei
A1  - Atalay, Mustafa
A1  - vanBeijsterveldt, Toos
A1  - Bergen, Nienke
A1  - Benke, Kelly
A1  - Berry, Diane J.
A1  - Coin, Lachlan
A1  - Davis, Oliver S. P.
A1  - Elliott, Paul
A1  - Flexeder, Claudia
A1  - Frayling, Tim
A1  - Gaillard, Romy
A1  - Groen-Blokhuis, Maria
A1  - Goh, Liang-Kee
A1  - Haworth, Claire M. A.
A1  - Hadley, Dexter
A1  - Hebebrand, Johannes
A1  - Hinney, Anke
A1  - Hirschhorn, Joel N.
A1  - Holloway, John W.
A1  - Holst, Claus
A1  - Hottenga, Jouke Jan
A1  - Horikoshi, Momoko
A1  - Huikari, Ville
A1  - Hypponen, Elina
A1  - Kilpelainen, Tuomas O.
A1  - Kirin, Mirna
A1  - Kowgier, Matthew
A1  - Lakka, Hanna-Maaria
A1  - Lange, Leslie A.
A1  - Lawlor, Debbie A.
A1  - Lehtimaki, Terho
A1  - Lewin, Alex
A1  - Lindgren, Cecilia
A1  - Lindi, Virpi
A1  - Maggi, Reedik
A1  - Marsh, Julie
A1  - Middeldorp, Christel
A1  - Millwood, Iona
A1  - Murray, Jeffrey C.
A1  - Nivard, Michel
A1  - Nohr, Ellen Aagaard
A1  - Ntalla, Ioanna
A1  - Oken, Emily
A1  - Panoutsopoulou, Kalliope
A1  - Pararajasingham, Jennifer
A1  - Rodriguez, Alina
A1  - Salem, Rany M.
A1  - Sebert, Sylvain
A1  - Siitonen, Niina
A1  - Strachan, David P.
A1  - Teo, Yik-Ying
A1  - Valcarcel, Beatriz
A1  - Willemsen, Gonneke
A1  - Zeggini, Eleftheria
A1  - Boomsma, Dorret I.
A1  - Cooper, Cyrus
A1  - Gillman, Matthew
A1  - Hocher, Berthold
A1  - Lakka, Timo A.
A1  - Mohlke, Karen L.
A1  - Dedoussis, George V.
A1  - Ong, Ken K.
A1  - Pearson, Ewan R.
A1  - Price, Thomas S.
A1  - Power, Chris
A1  - Raitakari, Olli T.
A1  - Saw, Seang-Mei
A1  - Scherag, Andre
A1  - Simell, Olli
A1  - Sorensen, Thorkild I. A.
A1  - Wilson, James F.
T1  - Common variants at 6q22 and 17q21 are associated with intracranial volume
JF  - Nature genetics
N2  - During aging, intracranial volume remains unchanged and represents maximally attained brain size, while various interacting biological phenomena lead to brain volume loss. Consequently, intracranial volume and brain volume in late life reflect different genetic influences. Our genome-wide association study (GWAS) in 8,175 community-dwelling elderly persons did not reveal any associations at genome-wide significance (P < 5 x 10(-8)) for brain volume. In contrast, intracranial volume was significantly associated with two loci: rs4273712 (P = 3.4 x 10(-11)), a known height-associated locus on chromosome 6q22, and rs9915547 (P = 1.5 x 10(-12)), localized to the inversion on chromosome 17q21. We replicated the associations of these loci with intracranial volume in a separate sample of 1,752 elderly persons (P = 1.1 x 10(-3) for 6q22 and 1.2 x 10(-3) for 17q21). Furthermore, we also found suggestive associations of the 17q21 locus with head circumference in 10,768 children (mean age of 14.5 months). Our data identify two loci associated with head size, with the inversion at 17q21 also likely to be involved in attaining maximal brain size.
Y1  - 2012
U6  - https://doi.org/10.1038/ng.2245
SN  - 1061-4036
VL  - 44
IS  - 5
SP  - 539
EP  - +
PB  - Nature Publ. Group
CY  - New York
ER  - 
TY  - JOUR
A1  - Schmidt, Bernd
A1  - Kunz, Oliver
T1  - alpha,beta-Unsaturated delta-Valerolactones through RCM-Isomerization Sequence
JF  - Synlett : accounts and rapid communications in synthetic organic chemistry
N2  - alpha,beta-Unsaturated d-lactones are accessible via a sequential ring-closing metathesis (RCM) double-bond migration reaction starting from butenoates of allyl alcohols. This approach proceeds efficiently with lower catalyst loadings and higher initial substrate concentrations compared to the alternative RCM of acrylates derived from homoallylic alcohols.
KW  - ruthenium
KW  - lactones
KW  - tandem reactions
KW  - metathesis
KW  - esters
Y1  - 2012
U6  - https://doi.org/10.1055/s-0031-1290488
SN  - 0936-5214
IS  - 6
SP  - 851
EP  - 854
PB  - Thieme
CY  - Stuttgart
ER  -