TY - JOUR A1 - Cuong Nguyen Huu, A1 - Kappel, Christian A1 - Keller, Barbara A1 - Sicard, Adrien A1 - Takebayashi, Yumiko A1 - Breuninger, Holger A1 - Nowak, Michael D. A1 - Bäurle, Isabel A1 - Himmelbach, Axel A1 - Burkart, Michael A1 - Ebbing-Lohaus, Thomas A1 - Sakakibara, Hitoshi A1 - Altschmied, Lothar A1 - Conti, Elena A1 - Lenhard, Michael T1 - Presence versus absence of CYP734A50 underlies the style-length dimorphism in primroses JF - eLife N2 - Heterostyly is a wide-spread floral adaptation to promote outbreeding, yet its genetic basis and evolutionary origin remain poorly understood. In Primula (primroses), heterostyly is controlled by the S-locus supergene that determines the reciprocal arrangement of reproductive organs and incompatibility between the two morphs. However, the identities of the component genes remain unknown. Here, we identify the Primula CYP734A50 gene, encoding a putative brassinosteroid-degrading enzyme, as the G locus that determines the style-length dimorphism. CYP734A50 is only present on the short-styled S-morph haplotype, it is specifically expressed in S-morph styles, and its loss or inactivation leads to long styles. The gene arose by a duplication specific to the Primulaceae lineage and shows an accelerated rate of molecular evolution. Thus, our results provide a mechanistic explanation for the Primula style-length dimorphism and begin to shed light on the evolution of the S-locus as a prime model for a complex plant supergene. Y1 - 2016 U6 - https://doi.org/10.7554/eLife.17956 SN - 2050-084X VL - 5 PB - eLife Sciences Publications CY - Cambridge ER - TY - GEN A1 - Nowak, Michael D. A1 - Russo, Giancarlo A1 - Schlapbach, Ralph A1 - Huu, Cuong Nguyen A1 - Lenhard, Michael A1 - Conti, Elena T1 - The draft genome of Primula veris yields insights into the molecular basis of heterostyly T2 - Postprints der Universität Potsdam : Mathematisch Naturwissenschaftliche Reihe N2 - Background The flowering plant Primula veris is a common spring blooming perennial that is widely cultivated throughout Europe. This species is an established model system in the study of the genetics, evolution, and ecology of heterostylous floral polymorphisms. Despite the long history of research focused on this and related species, the continued development of this system has been restricted due the absence of genomic and transcriptomic resources. Results We present here a de novo draft genome assembly of P. veris covering 301.8 Mb, or approximately 63% of the estimated 479.22 Mb genome, with an N50 contig size of 9.5 Kb, an N50 scaffold size of 164 Kb, and containing an estimated 19,507 genes. The results of a RADseq bulk segregant analysis allow for the confident identification of four genome scaffolds that are linked to the P. veris S-locus. RNAseq data from both P. veris and the closely related species P. vulgaris allow for the characterization of 113 candidate heterostyly genes that show significant floral morph-specific differential expression. One candidate gene of particular interest is a duplicated GLOBOSA homolog that may be unique to Primula (PveGLO2), and is completely silenced in L-morph flowers. Conclusions The P. veris genome represents the first genome assembled from a heterostylous species, and thus provides an immensely important resource for future studies focused on the evolution and genetic dissection of heterostyly. As the first genome assembled from the Primulaceae, the P. veris genome will also facilitate the expanded application of phylogenomic methods in this diverse family and the eudicots as a whole. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 879 KW - pollen flow KW - reproductive success KW - natural-populations KW - genetic-variation KW - breeding system KW - floral morph KW - evolution KW - vulgaris KW - identification KW - transcriptome KW - Genome Assembly KW - Veris KW - Transcriptome Assembly KW - Corolla Tube KW - Genome Scaffold Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-435088 SN - 1866-8372 IS - 879 ER - TY - JOUR A1 - Nowak, Michael D. A1 - Russo, Giancarlo A1 - Schlapbach, Ralph A1 - Cuong Nguyen Huu, A1 - Lenhard, Michael A1 - Conti, Elena T1 - The draft genome of Primula veris yields insights into the molecular basis of heterostyly JF - Genome biology : biology for the post-genomic era N2 - Background: The flowering plant Primula veris is a common spring blooming perennial that is widely cultivated throughout Europe. This species is an established model system in the study of the genetics, evolution, and ecology of heterostylous floral polymorphisms. Despite the long history of research focused on this and related species, the continued development of this system has been restricted due the absence of genomic and transcriptomic resources. Results: We present here a de novo draft genome assembly of P. veris covering 301.8 Mb, or approximately 63% of the estimated 479.22 Mb genome, with an N50 contig size of 9.5 Kb, an N50 scaffold size of 164 Kb, and containing an estimated 19,507 genes. The results of a RADseq bulk segregant analysis allow for the confident identification of four genome scaffolds that are linked to the P. veris S-locus. RNAseq data from both P. veris and the closely related species P. vulgaris allow for the characterization of 113 candidate heterostyly genes that show significant floral morph-specific differential expression. One candidate gene of particular interest is a duplicated GLOBOSA homolog that may be unique to Primula (PveGLO2), and is completely silenced in L-morph flowers. Conclusions: The P. veris genome represents the first genome assembled from a heterostylous species, and thus provides an immensely important resource for future studies focused on the evolution and genetic dissection of heterostyly. As the first genome assembled from the Primulaceae, the P. veris genome will also facilitate the expanded application of phylogenomic methods in this diverse family and the eudicots as a whole. Y1 - 2015 U6 - https://doi.org/10.1186/s13059-014-0567-z SN - 1465-6906 SN - 1474-760X VL - 16 PB - BioMed Central CY - London ER - TY - GEN A1 - Sahlmann, Kristina A1 - Clemens, Vera A1 - Nowak, Michael A1 - Schnor, Bettina T1 - MUP BT - Simplifying Secure Over-The-Air Update with MQTT for Constrained IoT Devices T2 - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe N2 - Message Queuing Telemetry Transport (MQTT) is one of the dominating protocols for edge- and cloud-based Internet of Things (IoT) solutions. When a security vulnerability of an IoT device is known, it has to be fixed as soon as possible. This requires a firmware update procedure. In this paper, we propose a secure update protocol for MQTT-connected devices which ensures the freshness of the firmware, authenticates the new firmware and considers constrained devices. We show that the update protocol is easy to integrate in an MQTT-based IoT network using a semantic approach. The feasibility of our approach is demonstrated by a detailed performance analysis of our prototype implementation on a IoT device with 32 kB RAM. Thereby, we identify design issues in MQTT 5 which can help to improve the support of constrained devices. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 1094 KW - Internet of Things KW - security KW - firmware update KW - MQTT KW - edge computing Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-489013 SN - 1866-8372 IS - 1094 ER - TY - JOUR A1 - Sahlmann, Kristina A1 - Clemens, Vera A1 - Nowak, Michael A1 - Schnor, Bettina T1 - MUP BT - Simplifying Secure Over-The-Air Update with MQTT for Constrained IoT Devices JF - Sensors N2 - Message Queuing Telemetry Transport (MQTT) is one of the dominating protocols for edge- and cloud-based Internet of Things (IoT) solutions. When a security vulnerability of an IoT device is known, it has to be fixed as soon as possible. This requires a firmware update procedure. In this paper, we propose a secure update protocol for MQTT-connected devices which ensures the freshness of the firmware, authenticates the new firmware and considers constrained devices. We show that the update protocol is easy to integrate in an MQTT-based IoT network using a semantic approach. The feasibility of our approach is demonstrated by a detailed performance analysis of our prototype implementation on a IoT device with 32 kB RAM. Thereby, we identify design issues in MQTT 5 which can help to improve the support of constrained devices. KW - Internet of Things KW - security KW - firmware update KW - MQTT KW - edge computing Y1 - 2020 U6 - https://doi.org/10.3390/s21010010 SN - 1424-8220 VL - 21 IS - 1 PB - MDPI CY - Basel ER - TY - JOUR A1 - Grinberg, Victoria A1 - Hell, Natalie A1 - El Mellah, Ileyk A1 - Neilsen, Joseph A1 - Sander, Andreas Alexander Christoph A1 - Leutenegger, Maurice A1 - Fürst, Felix A1 - Huenemoerder, David P. A1 - Kretschmar, Peter A1 - Kuehnel, Matthias A1 - Martinez-Nunez, Silvia A1 - Niu, Shu A1 - Pottschmidt, Katja A1 - Schulz, Norbert S. A1 - Wilms, Joern A1 - Nowak, Michael A. T1 - The clumpy absorber in the high-mass X-ray binary Vela X-1 JF - Astronomy and astrophysics : an international weekly journal N2 - Bright and eclipsing, the high-mass X-ray binary Vela X-1 offers a unique opportunity to study accretion onto a neutron star from clumpy winds of O/B stars and to disentangle the complex accretion geometry of these systems. In Chandra-HETGS spectroscopy at orbital phase similar to 0.25, when our line of sight towards the source does not pass through the large-scale accretion structure such as the accretion wake, we observe changes in overall spectral shape on timescales of a few kiloseconds. This spectral variability is, at least in part, caused by changes in overall absorption and we show that such strongly variable absorption cannot be caused by unperturbed clumpy winds of O/B stars. We detect line features from high and low ionization species of silicon, magnesium, and neon whose strengths and presence depend on the overall level of absorption. These features imply a co-existence of cool and hot gas phases in the system, which we interpret as a highly variable, structured accretion flow close to the compact object such as has been recently seen in simulations of wind accretion in high-mass X-ray binaries. KW - X-rays: individuals: Vela X-1 KW - X-rays: binaries KW - stars: winds, outflows KW - stars: massive Y1 - 2017 U6 - https://doi.org/10.1051/0004-6361/201731843 SN - 1432-0746 VL - 608 PB - EDP Sciences CY - Les Ulis ER - TY - BOOK A1 - Berner, Elisabeth A1 - Hoffmann, Michael A1 - Mühlbauer, Evelyn A1 - Höfner, Marion A1 - Weber, Carina A1 - Giers, Ursula A1 - Wiese, Heike A1 - Freywald, Ulrike A1 - Mayr, Katharina A1 - Nowak, Měto A1 - Föllner, Ursula A1 - Luther, Saskia A1 - Goltz, Reinhard ED - Berner, Elisabeth T1 - Region – Sprache – Literatur BT - Unterrichtsanregungen und Materialien für den Deutschunterricht in der Primar- und Sekundarstufe N2 - Mit dem neuen Rahmenlehrplan für die Länder Brandenburg und Berlin wird der Kompetenzentwicklung der Schülerinnen und Schüler unter den Bedingungen lebensweltlicher Erfahrungen ein besonderer Stellenwert beigemessen. Der Sammelband enthält Beiträge, in denen den Lehrerinnen und Lehrern vielfältige Unterrichtsmaterialien und didaktische Anregungen für einen praxisnahen, entdeckenden Unterricht in der Primar- und Sekundarstufe für den Deutschunterricht vorgestellt werden. Diese reichen von theoretischen Grundlagen, über einzelne Unterrichtssequenzen und Projekte bis zur Darstellung einer Lernspirale für die Jahrgangsstufen 1 bis 10. Vielfältige, auch multimediale Zugänge bis zum spielerischen Umgang mit der Sprache zeigen, dass Sprache kein „trockener“ Lerngegenstand sein muss. Die Beiträge geben darüber hinaus Einblicke in die fachlichen Hintergründe, die helfen sollen, den Zugang zu den einzelnen Gegenständen zu erleichtern. Das thematische Zentrum „Region“ bildet den Ausgangspunkt für die Einbeziehung des Niederdeutschen, Sorbischen, Berlinischen, Kiezdeutschen sowie der Dialekte. Dabei werden sowohl literarische als auch Sachtexte berücksichtigt. KW - Sprache KW - Region KW - Literatur KW - Deutschunterricht KW - Unterrichtsmaterialien KW - didaktische Anregungen KW - Berlinisch KW - Kiezdeutsch KW - Sorbisch Y1 - 2017 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-400098 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Ipsen, Marie Josephin A1 - Nowak-Szczepanska, Natalia A1 - Gomula, A. A1 - Assmann, Christian A1 - Hermanussen, Michael T1 - The association of body height, height variability and inequality JF - Journal of biological and clinical anthropology : Anthropologischer Anzeiger ; Mitteilungsorgan der Gesellschaft für Anthropologie N2 - Body height is associated with environmental conditions. It has been suggested that under poor conditions when inequality within a population increases, also the variability in height tends to increase. We studied the association of body height, within-country variability in height and geographic and historic origin in 767 growth studies carried out in 80 countries, published between 1794 and 2013, with data on N = 78,184 infants age 2 years, and N = 2,130,729 juveniles age 7 years. The studies represent almost the whole spectrum of economic diversity in human societies since the end-18 th century. 207 studies contained data for both infants and juveniles with 50,819 subjects (age 2), and 123,078 subjects (age 7). Multiple linear regressions showed significant interactions between height, sex, historic year of the study, geographic origin, and within-study standard deviation for height with multiple R-squared = 0.527, p < 0.001, at age 2, and multiple R-squared = 0.436, p < 0.001, at age 7. Yet, the two age groups differed in respect to within-study standard deviation for height. We found a significant association between body height and within-study standard deviation for height only at age 2: tall infant populations are less variable in height (r = –0.27, p < 0.01). There was no such association in children aged 7 years. Tall children from affluent and short children from less affluent countries do not differ in the variability of body height. The data suggest that the 'environmental adversity' hypothesis for variation in growth: small mean values for height go along with large standard deviations for height, does not apply for children at age 7. KW - standard deviation for height KW - historic growth studies KW - environmental adversity KW - inequality Y1 - 2016 U6 - https://doi.org/10.1127/anthranz/2015/0623 SN - 0003-5548 VL - 73 SP - 1 EP - 6 PB - Schweizerbart CY - Stuttgart ER - TY - JOUR A1 - Gomula, Aleksandra A1 - Nowak-Szczepanska, Natalia A1 - Hermanussen, Michael A1 - Scheffler, Christiane A1 - Koziel, Slawomir T1 - Trends in growth and developmental tempo in boys aged 7 to 18 years between 1966 and 2012 in Poland JF - American journal of human biology : the official journal of the Human Biology Council N2 - Objectives: To assess trends in growth in different developmental periods and trends in developmental tempo in Polish boys between 1966 and 2012. Methods: Data on 34 828 boys aged 7 to 18 years were collected during Polish Anthropological Surveys conducted in 1966, 1978, 1988, and 2012. Biological parameters, related to onset of adolescent growth spurt (OGS) and peak height velocity (PHV), were derived from a Preece-Baines 1 model (PB1). Childhood (height at 7 years of age), pre-adolescent (height at OGS) and adolescent growth (adult height minus height at OGS) were identified. Results: Positive secular trend between 1966 and 2012 in adult height accounted for, on average, 1.5 cm/decade, with varying intensity between the Surveys. Decline in both age at OGS and APHV between 1966 and 2012 (1.5 and 1.4 years, respectively) indicated an acceleration in developmental tempo, on average, by 0.3 year/decade. Increases in the contribution to the trend in adult height gained during growth in particular developmental periods between 1966 and 2012 were as followed-childhood: 0.6%, pre-adolescent growth: -3.1%, adolescent growth: 3.1%. Conclusions: Secular trend in developmental tempo and growth among boys reflects changes in living conditions and socio-political aspirations in Poland during nearly 50 years. Acceleration in tempo is already visible at age at OGS, whereas the trend in adult height occurs largely during adolescence, pointing to different regulation of developmental tempo and growth in body height. This finding emphasizes the importance of extending public health intervention into children's growth up until adolescence. Y1 - 2020 U6 - https://doi.org/10.1002/ajhb.23548 SN - 1042-0533 SN - 1520-6300 VL - 33 IS - 6 PB - Wiley CY - Hoboken ER - TY - BOOK A1 - Mientus, Lukas A1 - Klempin, Christiane A1 - Nowak, Anna A1 - Wyss, Corinne A1 - Aufschnaiter, Claudia von A1 - Faix, Ann-Christin A1 - te Poel, Kathrin A1 - Wahbe, Nadia A1 - Pieper, Martin A1 - Höller, Katharina A1 - Kallenbach, Lea A1 - Förster, Magdalena A1 - Redecker, Anke A1 - Dick, Mirjam A1 - Holle, Jörg A1 - Schneider, Edina A1 - Rehfeldt, Daniel A1 - Brauns, Sarah A1 - Abels, Simone A1 - Ferencik-Lehmkuhl, Daria A1 - Fränkel, Silvia A1 - Frohn, Julia A1 - Liebsch, Ann-Catherine A1 - Pech, Detlef A1 - Schreier, Pascal A1 - Jessen, Moiken A1 - Großmann, Uta A1 - Skintey, Lesya A1 - Voerkel, Paul A1 - Vaz Ferreira, Mergenfel A. A1 - Zimmermann, Jan-Simon A1 - Buddeberg, Magdalena A1 - Henke, Vanessa A1 - Hornberg, Sabine A1 - Völschow, Yvette A1 - Warrelmann, Julia-Nadine A1 - Malek, Jennifer A1 - Tinnefeld, Anja A1 - Schmidt, Peggy A1 - Bauer, Tobias A1 - Jänisch, Christopher A1 - Spitzer, Lisa A1 - Franken, Nadine A1 - Degeling, Maria A1 - Preisfeld, Angelika A1 - Meier, Jana A1 - Küth, Simon A1 - Scholl, Daniel A1 - Vogelsang, Christoph A1 - Watson, Christina A1 - Weißbach, Anna A1 - Kulgemeyer, Christoph A1 - Oetken, Mandy A1 - Gorski, Sebastian A1 - Kubsch, Marcus A1 - Sorge, Stefan A1 - Wulff, Peter A1 - Fellenz, Carolin D. A1 - Schnell, Susanne A1 - Larisch, Cathleen A1 - Kaiser, Franz A1 - Knott, Christina A1 - Reimer, Stefanie A1 - Stegmüller, Nathalie A1 - Boukrayâa Trabelsi, Kathrin A1 - Schißlbauer, Franziska A1 - Lemberger, Lukas A1 - Barth, Ulrike A1 - Wiehl, Angelika A1 - Rogge, Tim A1 - Böhnke, Anja A1 - Dietz, Dennis A1 - Großmann, Leroy A1 - Wienmeister, Annett A1 - Zoppke, Till A1 - Jiang, Lisa A1 - Grünbauer, Stephanie A1 - Ostersehlt, Dörte A1 - Peukert, Sophia A1 - Schäfer, Christoph A1 - Löbig, Anna A1 - Bröll, Leena A1 - Brandt, Birgit A1 - Breuer, Meike A1 - Dausend, Henriette A1 - Krelle, Michael A1 - Andersen, Gesine A1 - Falke, Sascha A1 - Kindermann-Güzel, Kristin A1 - Körner, Katrina A1 - Lottermoser, Lisa-Marie A1 - Pügner, Kati A1 - Sonnenburg, Nadine A1 - Akarsu, Selim A1 - Rechl, Friederike A1 - Gadinger, Laureen A1 - Heinze, Lena A1 - Wittmann, Eveline A1 - Franke, Manuela A1 - Lachmund, Anne-Marie A1 - Böttger, Julia A1 - Hannover, Bettina A1 - Behrendt, Renata A1 - Conty, Valentina A1 - Grundmann, Stephanie A1 - Ghassemi, Novid A1 - Opitz, Ben A1 - Brämer, Martin A1 - Gasparjan, David A1 - Sambanis, Michaela A1 - Köster, Hilde A1 - Lücke, Martin A1 - Nordmeier, Volkhard A1 - Schaal, Sonja A1 - Haberbosch, Maximilian A1 - Meissner, Maren A1 - Schaal, Steffen A1 - Brüchner, Melanie A1 - Riehle, Tamara A1 - Leopold, Bengta Marie A1 - Gerlach, Susanne A1 - Rau-Patschke, Sarah A1 - Skorsetz, Nina A1 - Weber, Nadine A1 - Damköhler, Jens A1 - Elsholz, Markus A1 - Trefzger, Thomas A1 - Lewek, Tobias A1 - Borowski, Andreas ED - Mientus, Lukas ED - Klempin, Christiane ED - Nowak, Anna T1 - Reflexion in der Lehrkräftebildung BT - Empirisch – Phasenübergreifend – Interdisziplinär T3 - Potsdamer Beiträge für Lehrkräftebildung und Bildungsforschung N2 - Reflexion ist eine Schlüsselkategorie für die professionelle Entwicklung von Lehrkräften, welche als Ausbildungsziel in den Bildungsstandards für die Lehrkräftebildung verankert ist. Eine Verstetigung universitär geprägter Forschung und Modellierung in der praxisnahen Anwendung im schulischen Kontext bietet Potentiale nachhaltiger Professionalisierung. Die Stärkung reflexionsbezogener Kompetenzen durch Empirie und Anwendung scheint eine phasenübergreifende Herausforderung der Lehrkräftebildung zu sein, die es zu bewältigen gilt. Ziele des Tagungsbandes Reflexion in der Lehrkräftebildung sind eine theoretische Schärfung des Konzeptes „Reflexive Professionalisierung“ und der Austausch über Fragen der Einbettung wirksamer reflexionsbezogener Lerngelegenheiten in die Lehrkräftebildung. Forschende und Lehrende der‚ drei Phasen (Studium, Referendariat sowie Fort- und Weiterbildung) der Lehrkräftebildung stellen Lehrkonzepte und Forschungsprojekte zum Thema Reflexion in der Lehrkräftebildung vor und diskutieren diese. Gemeinsam mit Teilnehmenden aller Phasen und von verschiedenen Standorten der Lehrkräftebildung werden zukünftige Herausforderungen identifiziert und Lösungsansätze herausgearbeitet. T3 - Potsdamer Beiträge zur Lehrkräftebildung und Bildungsforschung - 4 KW - Reflexion KW - Lehrkräftebildung KW - Reflexionskompetenz KW - Reflexivität KW - Feedback KW - Reflection KW - Teacher Education KW - Reflection Skills KW - Reflexivity KW - Feedback Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-591717 SN - 978-3-86956-566-8 SN - 2626-3556 SN - 2626-4722 IS - 4 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Torrejon, Jose M. A1 - Schulz, Norbert S. A1 - Nowak, Michael A. A1 - Oskinova, Lida A1 - Rodes-Roca, Jose J. A1 - Shenar, Tomer A1 - Wilms, Jörn T1 - On the radial onset of clumping in the wind of the B0I massive star QV nor JF - The astrophysical journal : an international review of spectroscopy and astronomical physics N2 - We present an analysis of a 78 ks Chandra high-energy transmission gratings observation of the B0I star QV Nor, the massive donor of the wind-accreting pulsar 4U1538-52. The neutron star (NS) orbits its companion in a very close orbit (r < 1.4R(*), in units of the stellar radii), thereby allowing probing of the innermost wind regions. The flux of the Fe K alpha line during eclipse reduces to only similar to 30% of the flux measured out of eclipse. This indicates that the majority of Fe fluorescence must be produced in regions close to the NS, at distances smaller than 1R(*) from its surface. The fact that the flux of the continuum decreases to only similar to 3% during eclipse allows for a high contrast of the Fe Ka line fluorescence during eclipse. The line is not resolved and centered at lambda = 1.9368(-0.0018)(+0.0032) angstrom. From the inferred plasma speed limit of v < c Delta lambda/lambda < 800 km s(-1) and range of ionization parameters of log xi =[-1, 2], together with the stellar density profile, we constrain the location of the cold, dense material in the stellar wind of QV Nor using simple geometrical considerations. We then use the Fe K alpha line fluorescence as a tracer of wind clumps and determine that these clumps in the stellar wind of QV Nor (B0I) must already be present at radii r < 1.25R(*), close to the photosphere of the star. KW - stars: individual (QV Nor, 4U1538+52) KW - stars: winds, outflows KW - X-rays: binaries Y1 - 2015 U6 - https://doi.org/10.1088/0004-637X/810/2/102 SN - 0004-637X SN - 1538-4357 VL - 810 IS - 2 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Hermanussen, Michael A1 - Scheffler, Christiane A1 - Martin, Lidia A1 - Groth, Detlef A1 - Waxmonsky, James G. A1 - Swanson, James A1 - Nowak-Szczepanska, Natalia A1 - Gomula, Aleksandra A1 - Apanasewicz, Anna A1 - Konarski, Jan M. A1 - Malina, Robert M. A1 - Bartkowiak, Sylwia A1 - Lebedeva, Lidia A1 - Suchomlinov, Andrej A1 - Konstantinov, Vsevolod A1 - Blum, Werner A1 - Limony, Yehuda A1 - Chakraborty, Raja A1 - Kirchengast, Sylvia A1 - Tutkuviene, Janina A1 - Jakimaviciene, Egle Marija A1 - Cepuliene, Ramune A1 - Franken, Daniel A1 - Navazo, Bárbara A1 - Moelyo, Annang G. A1 - Satake, Takashi A1 - Koziel, Slawomir ED - Scheffler, Christiane ED - Koziel, Slawomir ED - Hermanussen, Michael ED - Bogin, Barry T1 - Growth, Nutrition and Economy BT - Proceedings of the 27th Aschauer Soiree, held at Krobielowice, Poland, November 16th 2019 T2 - Human Biology and Public Health N2 - Twenty-three scientists met at Krobielowice, Poland to discuss the role of growth, nutrition and economy on body size. Contrasting prevailing concepts, re-analyses of studies in Indonesian and Guatemalan school children with high prevalence of stunting failed to provide evidence for an association between nutritional status and body height. Direct effects of parental education on growth that were not transmitted via nutrition were shown in Indian datasets using network analysis and novel statistical methods (St. Nicolas House Analysis) that translate correlation matrices into network graphs. Data on Polish children suggest significant impact of socioeconomic sensitivity on child growth, with no effect of maternal money satisfaction. Height and maturation tempo affect the position of a child among its peers. Correlations also exist between mood disorders and height. Secular changes in height and weight varied across decades independent of population size. Historic and recent Russian data showed that height of persons whose fathers performed manual work were on average four cm shorter than persons whose fathers were high-degree specialists. Body height, menarcheal age, and body proportions are sensitive to socioeconomic variables. Additional topics included delayed motherhood and its associations with newborn size; geographic and socioeconomic indicators related to low birth weight, prematurity and stillbirth rate; data on anthropometric history of Brazil, 1850-1950; the impact of central nervous system stimulants on the growth of children with attention-deficit/hyperactivity disorder; and pituitary development and growth hormone secretion. Final discussions debated on reverse causality interfering between social position, and adolescent growth and developmental tempo. KW - nutrition KW - stunting KW - socioeconomy KW - education KW - secular changes KW - pubertal timing Y1 - 2021 U6 - https://doi.org/10.52905/hbph.v1.1 SN - 2748-9957 VL - 2021 IS - 1 SP - 1 EP - 13 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - CHAP A1 - Kurbel, Karl A1 - Nowak, Dawid A1 - Azodi, Amir A1 - Jaeger, David A1 - Meinel, Christoph A1 - Cheng, Feng A1 - Sapegin, Andrey A1 - Gawron, Marian A1 - Morelli, Frank A1 - Stahl, Lukas A1 - Kerl, Stefan A1 - Janz, Mariska A1 - Hadaya, Abdulmasih A1 - Ivanov, Ivaylo A1 - Wiese, Lena A1 - Neves, Mariana A1 - Schapranow, Matthieu-Patrick A1 - Fähnrich, Cindy A1 - Feinbube, Frank A1 - Eberhardt, Felix A1 - Hagen, Wieland A1 - Plauth, Max A1 - Herscheid, Lena A1 - Polze, Andreas A1 - Barkowsky, Matthias A1 - Dinger, Henriette A1 - Faber, Lukas A1 - Montenegro, Felix A1 - Czachórski, Tadeusz A1 - Nycz, Monika A1 - Nycz, Tomasz A1 - Baader, Galina A1 - Besner, Veronika A1 - Hecht, Sonja A1 - Schermann, Michael A1 - Krcmar, Helmut A1 - Wiradarma, Timur Pratama A1 - Hentschel, Christian A1 - Sack, Harald A1 - Abramowicz, Witold A1 - Sokolowska, Wioletta A1 - Hossa, Tymoteusz A1 - Opalka, Jakub A1 - Fabisz, Karol A1 - Kubaczyk, Mateusz A1 - Cmil, Milena A1 - Meng, Tianhui A1 - Dadashnia, Sharam A1 - Niesen, Tim A1 - Fettke, Peter A1 - Loos, Peter A1 - Perscheid, Cindy A1 - Schwarz, Christian A1 - Schmidt, Christopher A1 - Scholz, Matthias A1 - Bock, Nikolai A1 - Piller, Gunther A1 - Böhm, Klaus A1 - Norkus, Oliver A1 - Clark, Brian A1 - Friedrich, Björn A1 - Izadpanah, Babak A1 - Merkel, Florian A1 - Schweer, Ilias A1 - Zimak, Alexander A1 - Sauer, Jürgen A1 - Fabian, Benjamin A1 - Tilch, Georg A1 - Müller, David A1 - Plöger, Sabrina A1 - Friedrich, Christoph M. A1 - Engels, Christoph A1 - Amirkhanyan, Aragats A1 - van der Walt, Estée A1 - Eloff, J. H. P. A1 - Scheuermann, Bernd A1 - Weinknecht, Elisa ED - Meinel, Christoph ED - Polze, Andreas ED - Oswald, Gerhard ED - Strotmann, Rolf ED - Seibold, Ulrich ED - Schulzki, Bernhard T1 - HPI Future SOC Lab BT - Proceedings 2015 N2 - Das Future SOC Lab am HPI ist eine Kooperation des Hasso-Plattner-Instituts mit verschiedenen Industriepartnern. Seine Aufgabe ist die Ermöglichung und Förderung des Austausches zwischen Forschungsgemeinschaft und Industrie. Am Lab wird interessierten Wissenschaftlern eine Infrastruktur von neuester Hard- und Software kostenfrei für Forschungszwecke zur Verfügung gestellt. Dazu zählen teilweise noch nicht am Markt verfügbare Technologien, die im normalen Hochschulbereich in der Regel nicht zu finanzieren wären, bspw. Server mit bis zu 64 Cores und 2 TB Hauptspeicher. Diese Angebote richten sich insbesondere an Wissenschaftler in den Gebieten Informatik und Wirtschaftsinformatik. Einige der Schwerpunkte sind Cloud Computing, Parallelisierung und In-Memory Technologien. In diesem Technischen Bericht werden die Ergebnisse der Forschungsprojekte des Jahres 2015 vorgestellt. Ausgewählte Projekte stellten ihre Ergebnisse am 15. April 2015 und 4. November 2015 im Rahmen der Future SOC Lab Tag Veranstaltungen vor. KW - Future SOC Lab KW - Forschungsprojekte KW - Multicore Architekturen KW - In-Memory Technologie KW - Cloud Computing KW - maschinelles Lernen KW - künstliche Intelligenz Y1 - 2017 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-102516 ER - TY - JOUR A1 - Hermanussen, Michael A1 - Scheffler, Christiane A1 - Pulungan, Aman B. A1 - Bandyopadhyay, Arup Ratan A1 - Ghosh, Jyoti Ratan A1 - Özdemir, Ayşegül A1 - Koca Özer, Başak A1 - Musalek, Martin A1 - Lebedeva, Lidia A1 - Godina, Elena A1 - Bogin, Barry A1 - Tutkuviene, Janina A1 - Budrytė, Milda A1 - Gervickaite, Simona A1 - Limony, Yehuda A1 - Kirchengast, Sylvia A1 - Buston, Peter A1 - Groth, Detlef A1 - Rösler, Antonia A1 - Gasparatos, Nikolaos A1 - Erofeev, Sergei A1 - Novine, Masiar A1 - Navazo, Bárbara A1 - Dahinten, Silvia A1 - Gomuła, Aleksandra A1 - Nowak-Szczepańska, Natalia A1 - Kozieł, Sławomir T1 - Environment, social behavior, and growth BT - Proceedings of the 30th Aschauer Soiree, held at Krobielowice, Poland, June 18th 2022 JF - Human biology and public health N2 - Twenty-four scientists met for the annual Auxological conference held at Krobielowice castle, Poland, to discuss the diverse influences of the environment and of social behavior on growth following last year’s focus on growth and public health concerns (Hermanussen et al., 2022b). Growth and final body size exhibit marked plastic responses to ecological conditions. Among the shortest are the pygmoid people of Rampasasa, Flores, Indonesia, who still live under most secluded insular conditions. Genetics and nutrition are usually considered responsible for the poor growth in many parts of this world, but evidence is accumulating on the prominent impact of social embedding on child growth. Secular trends not only in the growth of height, but also in body proportions, accompany the secular changes in the social, economic and political conditions, with major influences on the emotional and educational circumstances under which the children grow up (Bogin, 2021). Aspects of developmental tempo and aspects of sports were discussed, and the impact of migration by the example of women from Bangladesh who grew up in the UK. Child growth was considered in particular from the point of view of strategic adjustments of individual size within the network of its social group. Theoretical considerations on network characteristics were presented and related to the evolutionary conservation of growth regulating hypothalamic neuropeptides that have been shown to link behavior and physical growth in the vertebrate species. New statistical approaches were presented for the evaluation of short term growth measurements that permit monitoring child growth at intervals of a few days and weeks. KW - St. Nicolas House Analysis KW - child growth KW - body proportions KW - social network KW - public health KW - migration Y1 - 2023 U6 - https://doi.org/10.52905/hbph2023.1.59 SN - 2748-9957 VL - 1 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Förster, Daniel W. A1 - Bull, James K. A1 - Lenz, Dorina A1 - Autenrieth, Marijke A1 - Paijmans, Johanna L. A. A1 - Kraus, Robert H. S. A1 - Nowak, Carsten A1 - Bayerl, Helmut A1 - Kühn, Ralph A1 - Saveljev, Alexander P. A1 - Sindicic, Magda A1 - Hofreiter, Michael A1 - Schmidt, Krzysztof A1 - Fickel, Jörns T1 - Targeted resequencing of coding DNA sequences for SNP discovery in nonmodel species JF - Molecular ecology resources N2 - Targeted capture coupled with high-throughput sequencing can be used to gain information about nuclear sequence variation at hundreds to thousands of loci. Divergent reference capture makes use of molecular data of one species to enrich target loci in other (related) species. This is particularly valuable for nonmodel organisms, for which often no a priori knowledge exists regarding these loci. Here, we have used targeted capture to obtain data for 809 nuclear coding DNA sequences (CDS) in a nonmodel organism, the Eurasian lynx Lynx lynx, using baits designed with the help of the published genome of a related model organism (the domestic cat Felis catus). Using this approach, we were able to survey intraspecific variation at hundreds of nuclear loci in L. lynx across the species’ European range. A large set of biallelic candidate SNPs was then evaluated using a high-throughput SNP genotyping platform (Fluidigm), which we then reduced to a final 96 SNP-panel based on assay performance and reliability; validation was carried out with 100 additional Eurasian lynx samples not included in the SNP discovery phase. The 96 SNP-panel developed from CDS performed very successfully in the identification of individuals and in population genetic structure inference (including the assignment of individuals to their source population). In keeping with recent studies, our results show that genic SNPs can be valuable for genetic monitoring of wildlife species. KW - CDS KW - conservation genetics KW - Eurasian lynx KW - genetic monitoring KW - hybridization capture KW - single nucleotide polymorphism Y1 - 2018 U6 - https://doi.org/10.1111/1755-0998.12924 SN - 1755-098X SN - 1755-0998 VL - 18 IS - 6 SP - 1356 EP - 1373 PB - Wiley CY - Hoboken ER - TY - BOOK A1 - Burkart, Michael A1 - Dierschke, Hartmut A1 - Hölzel, Norbert A1 - Nowak, Bernd A1 - Fartmann, Thomas T1 - Molinio-Arrhenatheretea = Kulturgrasland und verwandte Vegetationstypen. Teil 2: Molinietalia T3 - Synopsis der Pflanzengesellschaften Deutschlands Y1 - 2004 SN - 1433-8440 VL - 9 PB - Selbstverl. der Floristisch-Soziologischen Arbeitsgemeinschaft CY - Göttingen ER -