TY  - JOUR
A1  - Abdalla, Hassan E.
A1  - Abramowski, Attila
A1  - Aharonian, Felix A.
A1  - Benkhali, Faiçal Ait
A1  - Akhperjanian, A. G.
A1  - Angüner, Ekrem Oǧuzhan
A1  - Arrieta, M.
A1  - Aubert, Pierre
A1  - Backes, Michael
A1  - Balzer, Arnim
A1  - Barnard, Michelle
A1  - Becherini, Yvonne
A1  - Tjus, Julia Becker
A1  - Berge, David
A1  - Bernhard, Sabrina
A1  - Bernlöhr, K.
A1  - Birsin, E.
A1  - Blackwell, R.
A1  - Bottcher, Markus
A1  - Boisson, Catherine
A1  - Bolmont, J.
A1  - Bordas, Pol
A1  - Bregeon, Johan
A1  - Brun, Francois
A1  - Brun, Pierre
A1  - Bryan, Mark
A1  - Bulik, Tomasz
A1  - Capasso, M.
A1  - Carr, John
A1  - Casanova, Sabrina
A1  - Chakraborty, N.
A1  - Chalme-Calvet, R.
A1  - Chaves, Ryan C. G.
A1  - Chen, Andrew
A1  - Chevalier, J.
A1  - Chretien, M.
A1  - Colafrancesco, Sergio
A1  - Cologna, Gabriele
A1  - Condon, B.
A1  - Conrad, Jan
A1  - Couturier, C.
A1  - Cui, Y.
A1  - Davids, I. D.
A1  - Degrange, B.
A1  - Deil, Christoph
A1  - deWilt, P.
A1  - Djannati-Atai, Arache
A1  - Domainko, Wilfried
A1  - Donath, Axel
A1  - Dubus, Guillaume
A1  - Dutson, Kate
A1  - Dyks, J.
A1  - Dyrda, M.
A1  - Edwards, T.
A1  - Egberts, Kathrin
A1  - Eger, P.
A1  - Ernenwein, J. -P.
A1  - Eschbach, S.
A1  - Farnier, C.
A1  - Fegan, Stuart
A1  - Fernandes, M. V.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Foerster, A.
A1  - Funk, S.
A1  - Füßling, Matthias
A1  - Gabici, Stefano
A1  - Gajdus, M.
A1  - Gallant, Y. A.
A1  - Garrigoux, T.
A1  - Giavitto, Gianluca
A1  - Giebels, B.
A1  - Glicenstein, J. F.
A1  - Gottschall, Daniel
A1  - Goyal, A.
A1  - Grondin, M. -H.
A1  - Grudzinska, M.
A1  - Hadasch, Daniela
A1  - Hahn, J.
A1  - Hawkes, J.
A1  - Heinzelmann, G.
A1  - Henri, Gilles
A1  - Hermann, G.
A1  - Hervet, Olivier
A1  - Hillert, A.
A1  - Hinton, James Anthony
A1  - Hofmann, Werner
A1  - Hoischen, Clemens
A1  - Holler, M.
A1  - Horns, D.
A1  - Ivascenko, Alex
A1  - Jacholkowska, A.
A1  - Jamrozy, Marek
A1  - Janiak, M.
A1  - Jankowsky, D.
A1  - Jankowsky, Felix
A1  - Jingo, M.
A1  - Jogler, Tobias
A1  - Jouvin, Lea
A1  - Jung-Richardt, Ira
A1  - Kastendieck, M. A.
A1  - Katarzynski, Krzysztof
A1  - Katz, Uli
A1  - Kerszberg, D.
A1  - Khelifi, B.
A1  - Kieffer, M.
A1  - King, J.
A1  - Klepser, S.
A1  - Klochkov, Dmitry
A1  - Kluzniak, W.
A1  - Kolitzus, D.
A1  - Komin, Nu.
A1  - Kosack, K.
A1  - Krakau, S.
A1  - Kraus, Michael
A1  - Krayzel, F.
A1  - Kruger, P. P.
A1  - Laffon, H.
A1  - Lamanna, G.
A1  - Lau, Jeanie
A1  - Lees, J. -P.
A1  - Lefaucheur, J.
A1  - Lefranc, V.
A1  - Lemiere, A.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J. -P.
A1  - Leser, Eva
A1  - Lohse, Thomas
A1  - Lorentz, M.
A1  - Lui, R.
A1  - Lypova, Iryna
A1  - Marandon, Vincent
A1  - Marcowith, Alexandre
A1  - Mariaud, C.
A1  - Marx, R.
A1  - Maurin, G.
A1  - Maxted, N.
A1  - Mayer, Michael
A1  - Meintjes, Petrus Johannes
A1  - Menzler, U.
A1  - Meyer, Manuel
A1  - Mitchell, A. M. W.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Mora, K.
A1  - Moulin, Emmanuel
A1  - Murach, T.
A1  - de Naurois, Mathieu
A1  - Niederwanger, F.
A1  - Niemiec, J.
A1  - Oakes, L.
A1  - Odaka, Hirokazu
A1  - Ohm, Stefan
A1  - Oettl, S.
A1  - Ostrowski, M.
A1  - Oya, I.
A1  - Padovani, Marco
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Arribas, M. Paz
A1  - Pekeur, N. W.
A1  - Pelletier, G.
A1  - Petrucci, P. -O.
A1  - Peyaud, B.
A1  - Pita, S.
A1  - Poon, Helen
A1  - Prokhorov, Dmitry
A1  - Prokoph, Heike
A1  - Puehlhofer, Gerd
A1  - Punch, Michael
A1  - Quirrenbach, Andreas
A1  - Raab, S.
A1  - Reimer, Anita
A1  - Reimer, Olaf
A1  - Renaud, M.
A1  - de los Reyes, R.
A1  - Rieger, Frank
A1  - Romoli, Carlo
A1  - Rosier-Lees, S.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Rulten, C. B.
A1  - Sahakian, V.
A1  - Salek, David
A1  - Sanchez, David A.
A1  - Santangelo, Andrea
A1  - Sasaki, Manami
A1  - Schlickeiser, Reinhard
A1  - Schussler, F.
A1  - Schulz, Andreas
A1  - Schwanke, U.
A1  - Schwemmer, S.
A1  - Seyffert, A. S.
A1  - Shafi, N.
A1  - Simoni, R.
A1  - Sol, H.
A1  - Spanier, Felix
A1  - Spengler, G.
A1  - Spiess, F.
A1  - Stawarz, Lukasz
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Stinzing, F.
A1  - Stycz, K.
A1  - Sushch, Iurii
A1  - Tavernet, J. -P.
A1  - Tavernier, T.
A1  - Taylor, A. M.
A1  - Terrier, R.
A1  - Tluczykont, Martin
A1  - Trichard, C.
A1  - Tuffs, R.
A1  - van der Walt, Johan
A1  - van Eldik, Christopher
A1  - van Soelen, Brian
A1  - Vasileiadis, Georges
A1  - Veh, J.
A1  - Venter, C.
A1  - Viana, A.
A1  - Vincent, P.
A1  - Vink, Jacco
A1  - Voisin, F.
A1  - Voelk, Heinrich J.
A1  - Vuillaume, Thomas
A1  - Wadiasingh, Z.
A1  - Wagner, Stefan J.
A1  - Wagner, P.
A1  - Wagner, R. M.
A1  - White, R.
A1  - Wierzcholska, Alicja
A1  - Willmann, P.
A1  - Woernlein, A.
A1  - Wouters, Denis
A1  - Yang, R.
A1  - Zabalza, Victor
A1  - Zaborov, D.
A1  - Zacharias, M.
A1  - Zdziarski, A. A.
A1  - Zech, Andreas
A1  - Zefi, F.
A1  - Ziegler, A.
A1  - Zywucka, Natalia
T1  - Search for Dark Matter Annihilations towards the Inner Galactic Halo from 10 Years of Observations with HESS
JF  - Physical review letters
N2  - The inner region of the Milky Way halo harbors a large amount of dark matter (DM). Given its proximity, it is one of the most promising targets to look for DM. We report on a search for the annihilations of DM particles using gamma-ray observations towards the inner 300 pc of the Milky Way, with the H.E.S.S. array of ground-based Cherenkov telescopes. The analysis is based on a 2D maximum likelihood method using Galactic Center (GC) data accumulated by H.E.S.S. over the last 10 years (2004-2014), and does not show any significant gamma-ray signal above background. Assuming Einasto and Navarro-Frenk-White DM density profiles at the GC, we derive upper limits on the annihilation cross section <sigma nu >. These constraints are the strongest obtained so far in the TeV DM mass range and improve upon previous limits by a factor 5. For the Einasto profile, the constraints reach <sigma nu > values of 6 x 10(-26) cm(3) s(-1) in the W+W- channel for a DM particle mass of 1.5 TeV, and 2 x 10(-26) cm(3) s(-1) in the tau(+)tau(-) channel for a 1 TeV mass. For the first time, ground-based gamma-ray observations have reached sufficient sensitivity to probe <sigma nu > values expected from the thermal relic density for TeV DM particles.
Y1  - 2016
U6  - https://doi.org/10.1103/PhysRevLett.117.111301
SN  - 0031-9007
SN  - 1079-7114
VL  - 117
PB  - American Physical Society
CY  - College Park
ER  - 
TY  - GEN
A1  - Abramowski, Attila
A1  - Aharonian, Felix A.
A1  - Benkhali, Faical Ait
A1  - Akhperjanian, A. G.
A1  - Angüner, Ekrem Oǧuzhan
A1  - Backes, Michael
A1  - Balenderan, Shangkari
A1  - Balzer, Arnim
A1  - Barnacka, Anna
A1  - Becherini, Yvonne
A1  - Tjus, Julia Becker
A1  - Berge, David
A1  - Bernhard, Sabrina
A1  - Bernlöhr, Konrad
A1  - Birsin, E.
A1  - Biteau, Jonathan
A1  - Böttcher, Markus
A1  - Boisson, Catherine
A1  - Bolmont, J.
A1  - Bordas, Pol
A1  - Bregeon, Johan
A1  - Brun, Francois
A1  - Brun, Pierre
A1  - Bryan, Mark
A1  - Bulik, Tomasz
A1  - Carrigan, Svenja
A1  - Casanova, Sabrina
A1  - Chadwick, Paula M.
A1  - Chakraborty, Nachiketa
A1  - Chalme-Calvet, R.
A1  - Chaves, Ryan C. G.
A1  - Chretien, M.
A1  - Colafrancesco, Sergio
A1  - Cologna, Gabriele
A1  - Conrad, Jan
A1  - Couturier, Claire
A1  - Cui, Yudong
A1  - Davids, Isak Delberth
A1  - Degrange, Bernhard
A1  - Deil, Christoph
A1  - deWilt, P.
A1  - Djannati-Ataï, A.
A1  - Domainko, Wilfried
A1  - Donath, Axel
A1  - Dubus, G.
A1  - Dutson, K.
A1  - Dyks, J.
A1  - Dyrda, M.
A1  - Edwards, Tanya
A1  - Egberts, Kathrin
A1  - Eger, Peter
A1  - Espigat, P.
A1  - Farnier, C.
A1  - Fegan, Stephen
A1  - Feinstein, Fabrice
A1  - Fernandes, Milton Virgilio
A1  - Fernandez, Diane
A1  - Fiasson, A.
A1  - Fontaine, Gerard
A1  - Förster, Andreas
A1  - Fuessling, M.
A1  - Gabici, S.
A1  - Gajdus, M.
A1  - Gallant, Yves A.
A1  - Garrigoux, Tania
A1  - Giavitto, G.
A1  - Giebels, Berrie
A1  - Glicenstein, Jean-Francois
A1  - Gottschall, Daniel
A1  - Grondin, M. -H.
A1  - Grudzinska, M.
A1  - Hadasch, Daniela
A1  - Haeffner, S.
A1  - Hahn, Joachim
A1  - Harris, Jonathan
A1  - Heinzelmann, Götz
A1  - Henri, G.
A1  - Hermann, German
A1  - Hervet, O.
A1  - Hillert, Andreas
A1  - Hinton, James Anthony
A1  - Hofmann, Werner
A1  - Hofverberg, Petter
A1  - Holler, Markus
A1  - Horns, Dieter
A1  - Ivascenko, Alex
A1  - Jacholkowska, A.
A1  - Jahn, C.
A1  - Jamrozy, Marek
A1  - Janiak, M.
A1  - Jankowsky, F.
A1  - Jung-Richardt, I.
A1  - Kastendieck, Max Anton
A1  - Katarzynski, K.
A1  - Katz, U.
A1  - Kaufmann, S.
A1  - Khelifi, B.
A1  - Kieffer, Michel
A1  - Klepser, S.
A1  - Klochkov, Dmitry
A1  - Kluzniak, W.
A1  - Kolitzus, David
A1  - Komin, Nu
A1  - Kosack, Karl
A1  - Krakau, Steffen
A1  - Krayzel, F.
A1  - Krueger, Pat P.
A1  - Laffon, H.
A1  - Lamanna, G.
A1  - Lefaucheur, J.
A1  - Lefranc, Valentin
A1  - Lemiere, A.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J. -P.
A1  - Lohse, Thomas
A1  - Lopatin, A.
A1  - Lu, Chia-Chun
A1  - Marandon, Vincent
A1  - Marcowith, Alexandre
A1  - Marx, Ramin
A1  - Maurin, G.
A1  - Maxted, Nigel
A1  - Mayer, Michael
A1  - McComb, T. J. Lowry
A1  - Mehault, J.
A1  - Meintjes, P. J.
A1  - Menzler, Ulf
A1  - Meyer, M.
A1  - Mitchell, Alison M. W.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Mora, K.
A1  - Moulin, Emmanuel
A1  - Murach, Thomas
A1  - de Naurois, Mathieu
A1  - Niemiec, J.
A1  - Nolan, Sam J.
A1  - Oakes, Louise
A1  - Odaka, Hirokazu
A1  - Ohm, S.
A1  - Optiz, Björn
A1  - Ostrowski, Michal
A1  - Oya, I.
A1  - Panter, Michael
A1  - Parsons, R. Daniel
A1  - Arribas, M. Paz
A1  - Pekeur, Nikki W.
A1  - Pelletier, G.
A1  - Petrucci, P. -O.
A1  - Peyaud, B.
A1  - Pita, S.
A1  - Poon, Helen
A1  - Pühlhofer, Gerd
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Reichardt, I.
A1  - Reimer, Anita
A1  - Reimer, Olaf
A1  - Renaud, Metz
A1  - de los Reyes, Raquel
A1  - Rieger, Frank
A1  - Romoli, C.
A1  - Rosier-Lees, S.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Rulten, C. B.
A1  - Sahakian, Vardan
A1  - Salek, D.
A1  - Sanchez, David M.
A1  - Santangelo, Andrea
A1  - Schlickeiser, Reinhard
A1  - Schuessler, F.
A1  - Schulz, A.
A1  - Schwanke, Ullrich
A1  - Schwarzburg, S.
A1  - Schwemmer, S.
A1  - Sol, H.
A1  - Spanier, Felix
A1  - Spengler, G.
A1  - Spies, Franziska
A1  - Stawarz, Lukasz
A1  - Steenkamp, Riaan
A1  - Stegmann, Christian
A1  - Stinzing, F.
A1  - Stycz, K.
A1  - Sushch, Iurii
A1  - Tavernet, J. -P.
A1  - Tavernier, T.
A1  - Taylor, A. M.
A1  - Terrier, R.
A1  - Tluczykont, Martin
A1  - Trichard, C.
A1  - Valerius, K.
A1  - van Eldik, C.
A1  - van Soelen, B.
A1  - Vasileiadis, Georges
A1  - Veh, J.
A1  - Venter, Christo
A1  - Viana, Aion
A1  - Vincent, P.
A1  - Vink, Jacco
A1  - Völk, Heinrich J.
A1  - Volpe, Francesca
A1  - Vorster, Martine
A1  - Vuillaume, T.
A1  - Wagner, S. J.
A1  - Wagner, P.
A1  - Wagner, R. M.
A1  - Ward, Martin
A1  - Weidinger, Matthias
A1  - Weitzel, Quirin
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Willmann, P.
A1  - Woernlein, A.
A1  - Wouters, D.
A1  - Yang, Ruizhi
A1  - Zabalza, Victor
A1  - Zaborov, Dmitry
A1  - Zacharias, M.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Zechlin, Hannes -S.
T1  - H.E.S.S. detection of TeV emission from the interaction region between the supernova remnant G349.7+0.2 and a molecular cloud (vol 574, A100, 2015)
T2  - Astronomy and astrophysics : an international weekly journal
KW  - gamma rays: general
KW  - ISM: supernova remnants
KW  - ISM: clouds
KW  - errata, addenda
Y1  - 2015
U6  - https://doi.org/10.1051/0004-6361/201425070e
SN  - 1432-0746
VL  - 580
PB  - EDP Sciences
CY  - Les Ulis
ER  - 
TY  - JOUR
A1  - Rector, Michael V.
A1  - Intziegianni, Konstantina
A1  - Müller, Steffen
A1  - Mayer, Frank
A1  - Cassel, Michael
T1  - Reproducibility of an ankle joint rotation correction method for assessment of Achilles tendon elongation
JF  - Isokinetics and exercise science : official journal of the European Isokinetic Society
N2  - BACKGROUND: The Achilles tendon (AT) requires optimal material and mechanical properties to function properly. Calculation of these properties depends on accurate measurement of input parameters (i.e. tendon elongation). However, the measurement of AT elongation with ultrasound during maximum voluntary isometric contraction (MVIC) is overestimated by ankle joint rotation (AJR). Methods to correct the influence of this rotation on AT elongation exist, yet their reproducibility in clinical settings is unknown. OBJECTIVE: To evaluate the test-retest reproducibility of AT elongation during MVIC after AJR correction. METHODS: Ten participants attended test and retest measurements where they performed plantar-flexion MVIC on a dynamometer. Simultaneously, ultrasound recorded AT elongation as the displacement of the medial gastrocnemius-myotendinous junction, while an electrogoniometer measured AJR. The ankle was then passively rotated to the AJR achieved during MVIC and AT elongation again determined. Elongation was corrected by subtracting this passive AT elongation from the total AT elongation during MVIC. Reproducibility was evaluated using ICC (2.1), test-retest variability (TRV, %), Bland-Altman analyses (Bias +/- LoA [1.96*SD]) and standard error of the measurement (SEM). RESULTS: Corrected AT elongation reproducibility exhibited an ICC = 0.79, SEM = 0.2 cm and TRV = 20 +/- 19%. Bias +/- LoA were determined to be 0.0 +/- 0.8 cm. CONCLUSIONS: Using this ultrasound and electrogoniometer-based method, corrected AT elongation can be assessed reproducibly.
KW  - Ultrasonography
KW  - Achilles tendon
KW  - reproducibility
KW  - isokinetic
KW  - ankle joint rotation
Y1  - 2017
U6  - https://doi.org/10.3233/IES-160644
SN  - 0959-3020
SN  - 1878-5913
VL  - 25
IS  - 1
SP  - 47
EP  - 52
PB  - IOS Press
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Aichert, Ingrid
A1  - Staiger, Anja
A1  - Schulte-Mäter, Anne
A1  - Becker-Redding, Ulrike
A1  - Stahn, Corinna
A1  - Peschke, Claudia
A1  - Heide, Judith
A1  - Ott, Susan
A1  - Herrmann, Heike
A1  - Völsch, Juliane
A1  - Mayer, Jörg
A1  - Rohnke, Lucie
A1  - Frank, Ulrike
A1  - Stadie, Nicole
A1  - Jentsch, Nadine
A1  - Blech, Anke
A1  - Kurtenbach, Stephanie
A1  - Thieke, Johanna
A1  - Schröder, Astrid
A1  - Stahn, Corinna
A1  - Hörnig, Robin
A1  - Burchert, Frank
A1  - De Bleser, Ria
A1  - Heister, Julian
A1  - Bartels, Luise
A1  - Würzner, Kay-Michael
A1  - Böhme, Romy
A1  - Burmester, Juliane
A1  - Krajewski, Melanie
A1  - Nager, Wido
A1  - Jungehülsing, Gerhard Jan
A1  - Wartenburger, Isabell
A1  - Jöbges, Michael
A1  - Schwilling, Eleonore
A1  - Lidzba, Karen
A1  - Winkler, Susanne
A1  - Konietzko, Andreas
A1  - Krägeloh-Mann, Ingeborg
A1  - Rilling, Eva
A1  - Wilken, Rainer
A1  - Wismann, Kathrin
A1  - Glandorf, Birte
A1  - Hoffmann, Hannah
A1  - Hinnenkamp, Christiane
A1  - Rohlmann, Insa
A1  - Ludewigt, Jacqueline
A1  - Bittner, Christian
A1  - Orlov, Tatjana
A1  - Claus, Katrin
A1  - Ehemann, Christine
A1  - Winnecken, Andreas
A1  - Hummel, Katja
A1  - Breitenstein, Sarah
ED  - Wahl, Michael
ED  - Stahn, Corinna
ED  - Hanne, Sandra
ED  - Fritzsche, Tom
T1  - Spektrum Patholinguistik = Schwerpunktthema: Von der Programmierung zur Artikulation : Sprechapraxie bei Kindern und Erwachsenen
N2  - Das 3. Herbsttreffen Patholinguistik fand am 21. November 2009 an der Universität Potsdam statt. Der vorliegende Tagungsband enthält die drei Hauptvorträge zum Schwerpunktthema „Von der Programmierung zu Artikulation: Sprechapraxie bei Kindern und Erwachsenen“. Darüber hinaus enthält der Band die Beiträge aus dem Spektrum Patholinguistik, sowie die Abstracts der Posterpräsentationen.
N2  - The 3rd Herbsttreffen Patholinguistik was held on November 21st, 2009 at the University of Potsdam. These proceedings contain the three main lectures of the central topic „From programming to articulation: Apraxia of speech of children and adults “. Additionally this volume contains the contributions of Spektrum Patholinguistik, as well as the abstracts of the poster presentations.
T3  - Spektrum Patholinguistik - 3 
KW  - Patholinguistik
KW  - Sprechapraxie
KW  - Sprachtherapie
KW  - patholinguistics
KW  - apraxia of speech
KW  - speech and language therapy
Y1  - 2010
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-45470
SN  - 978-3-86956-079-3
SN  - 1869-3822
SN  - 1866-9433
IS  - 3
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - CHAP
A1  - Borowski, Andreas
A1  - Glowinski, Ingrid
A1  - Frister, Jonas
A1  - Höttecke, Dietmar
A1  - Buth, Katrin
A1  - Koenen, Jenna
A1  - Masanek, Nicole
A1  - Reichwein, Wilko
A1  - Scholten, Nina
A1  - Sprenger, Sandra
A1  - Stender, Peter
A1  - Wöhlke, Carina
A1  - Komorek, Michael
A1  - Freckmann, Janine
A1  - Hofmann, Josefine
A1  - Niesel, Verena
A1  - Richter, Chris
A1  - Mehlmann, Nelli
A1  - Bikner-Ahsbahs, Angelika
A1  - Unverricht, Katja
A1  - Schanze, Sascha
A1  - Bittorf, Robert Marten
A1  - Meier, Monique
A1  - Grospietsch, Finja
A1  - Mayer, Jürgen
A1  - Gimbel, Katharina
A1  - Ziepprecht, Kathrin
A1  - Hofmann, Judith
A1  - Kramer, Charlotte
A1  - Müller, Britta-Kornelia
A1  - Rohde, Andreas
A1  - Zühlsdorf, Felix
A1  - Winkler, Iris
A1  - Laging, Ralf
A1  - Peter, Carina
A1  - Schween, Michael
A1  - Härle, Gerhard
A1  - Busse, Beatrix
A1  - Mahner, Sebastian
A1  - Köstler, Verena
A1  - Kufner, Sabrina
A1  - Mägdefrau, Jutta
A1  - Müller, Christian
A1  - Beck, Christina
A1  - Kriehuber, Eva
A1  - Boch, Florian
A1  - Engl, Anna-Teresa
A1  - Helzel, Andreas
A1  - Pickert, Tina
A1  - Reiter, Christian
A1  - Blasini, Bettina
A1  - Nerdel, Claudia
A1  - Lewalter, Doris
A1  - Schiffhauer, Silke
A1  - Richter-Gebert, Jürgen
A1  - Bannert, Maria
A1  - Maahs, Mirjam
A1  - Reißner, Maria
A1  - Ungar, Patrizia
A1  - von Wachter, Jana-Kristin
A1  - Hellmann, Katharina
A1  - Zaki, Katja
A1  - Pohlenz, Philipp
ED  - Glowinski, Ingrid
ED  - Borowski, Andreas
ED  - Gillen, Julia
ED  - Schanze, Sascha
ED  - von Meien, Joachim
T1  - Kohärenz in der universitären Lehrerbildung
T1  - Coherence in teacher education at university
BT  - Vernetzung von Fachwissenschaft, Fachdidaktik und Bildungswissenschaften
BT  - linking studies in content knowledge, pedagogical content knowledge and pedagogical knowledge in teacher education
N2  - One area that is supported by the project “Qualitätsoffensive Lehrerbildung” (funded by BMBF) is the improvement of collaboration and coordination between studies in the discipline, studies in pedagogical content knowledge, and studies in pedagogical knowledge during teacher education at university. Aiming a better coordination among these three parts of teacher education at university, many of the supported projects have designed and realized university-specific approaches. 
 
This conference proceedings volume comprises contributions by 15 of these projects. Seven of those were introduced and discussed in workshops on the occasion of two cross-regional project-conferences in Hannover and Potsdam. Overall, the contributions give a theoretically funded as well as a practice-oriented overview of current approaches and concepts to achieve a better connection between study units concerning studies in content knowledge, pedagogical content knowledge and pedagogical knowledge in teacher education. The volume presents university projects, which take effect on different levels (at the level of curriculum and content, at a collegiate level, at the level of structural conditions of universities). The different approaches are described in a way that they can provide a basis for transfer to other subjects or further universities.  

The contributions are aimed at teacher educators as well as other actors working in the field of teaching- and quality development at universities. All of them can take transferable ideas and impulses from the described concepts and formats.
N2  - Eine verbesserte Zusammenarbeit und Abstimmung von Fachwissenschaft, Fachdidaktik, Bildungswissenschaften und schulpraktischen Lernorten ist einer der Förderbereiche der „Qualitätsoffensive Lehrerbildung“. Zahlreiche der geförderten Projekte haben für dieses Handlungsfeld im Bereich Vernetzung von Fachwissenschaft, Fachdidaktik und Bildungswissenschaften hochschulspezifische Maßnahmen konzipiert und umgesetzt.

Der vorliegende Tagungsband beinhaltet Beiträge von 15 entsprechenden Projekten, von denen sieben anlässlich von zwei standortübergreifenden Projekt-Tagungen in Hannover und Potsdam vorgestellt und in Workshops diskutiert wurden. Insgesamt geben die Beiträge einen theoretisch fundierten und gleichzeitig praxisorientierten Überblick über aktuelle Ansätze und Konzepte zur besseren Vernetzung fachwissenschaftlicher, fachdidaktischer und bildungswissenschaftlicher Studienanteile im Lehramtsstudium. Dargestellt werden Projektarbeiten der Hochschulen, die auf verschiedenen Ebenen wirksam werden (curricular-inhaltliche Ebene, kollegiale Ebene, hochschul-strukturelle Ebene). Die Maßnahmen sind so beschrieben, dass sie als Grundlage für einen Transfer auf andere Fächer bzw. andere Standorte genutzt werden können.

Die Beiträge richten sich an alle Lehrenden im Bereich der Lehramtsbildung sowie sonstige Akteure im Bereich der Lehr- und Qualitätsentwicklung an den Universitäten. Sie alle können den beschriebenen Konzepten und Umsetzungsformaten transferierbare Ideen und Impulse entnehmen.
KW  - Professionswissen
KW  - universitäre Lehrerbildung
KW  - Vernetzung Fachwissenschaft
KW  - Fachdidaktik
KW  - Bildungswissenschaft
KW  - Lehramtsstudium
KW  - teacher education
KW  - professional knowledge
KW  - content knowledge
KW  - pedagogical content knowledge
Y1  - 2018
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-414267
SN  - 978-3-86956-438-8
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Intziegianni, Konstantina
A1  - Cassel, Michael
A1  - Rauf, S.
A1  - White, S.
A1  - Rector, Michael V.
A1  - Kaplick, Hannes
A1  - Wahmkow, Gunnar
A1  - Kratzenstein, S.
A1  - Mayer, Frank
T1  - Influence of Age and Pathology on Achilles Tendon Properties During a Single-leg Jump
JF  - International journal of sports medicine
N2  - Prevalence of Achilles tendinopathy increases with age leading to a weaker tendon with predisposition to rupture. Conclusive evidence of the influence of age and pathology on Achilles tendon (AT) properties remains limited, as previous studies are based on standardized isometric conditions. The study investigates the influence of age and pathology on AT properties during single-leg vertical jump (SLVJ). 10 children (C), 10 asymptomatic adults (A), and 10 tendinopathic patients (T) were included. AT elongation [mm] from rest to maximal displacement during a SLVJ on a force-plate was sonographically assessed. AT compliance [mm/N]) and strain [%] was calculated by dividing elongation by peak ground reaction force [N] and length, respectively. One-way ANOVA followed by Bonferroni post-hoc correction (=0.05) were used to compare C with A and A with T. AT elongation (p=0.004), compliance (p=0.001), and strain were found to be statistically significant higher in C (27 +/- 3mm, 0.026 +/- 0.006[mm/N], 13 +/- 2%) compared to A (21 +/- 4mm, 0.017 +/- 0.005[mm/N], 10 +/- 2%). No statistically significant differences (p0.05) was found between A and T (25 +/- 5mm, 0.019 +/- 0.004[mm/N], 12 +/- 3%). During SLVJ, tendon responded differently in regards to age and pathology with children having the most compliant AT. Higher compliance found in healthy tendons might be considered as a protective factor against load-related injuries.
KW  - children
KW  - tendinopathy
KW  - compliance
KW  - dynamic
KW  - ultrasonography
Y1  - 2016
U6  - https://doi.org/10.1055/s-0042-108198
SN  - 0172-4622
SN  - 1439-3964
VL  - 37
SP  - 973
EP  - 978
PB  - Thieme
CY  - Stuttgart
ER  - 
TY  - JOUR
A1  - Abramowski, Attila
A1  - Aharonian, Felix A.
A1  - Benkhali, Faical  Ait
A1  - Akhperjanian, A. G.
A1  - Angüner, Ekrem Oǧuzhan
A1  - Anton, Gisela
A1  - Balenderan, Shangkari
A1  - Balzer, Arnim
A1  - Barnacka, Anna
A1  - Becherini, Yvonne
A1  - Tjus, J. Becker
A1  - Bernlöhr, K.
A1  - Birsin, E.
A1  - Bissaldi, E.
A1  - Biteau, Jonathan
A1  - Boettcher, Markus
A1  - Boisson, Catherine
A1  - Bolmont, J.
A1  - Bordas, Pol
A1  - Brucker, J.
A1  - Brun, Francois
A1  - Brun, Pierre
A1  - Bulik, Tomasz
A1  - Carrigan, Svenja
A1  - Casanova, Sabrina
A1  - Cerruti, M.
A1  - Chadwick, Paula M.
A1  - Chalme-Calvet, R.
A1  - Chaves, Ryan C. G.
A1  - Cheesebrough, A.
A1  - Chretien, M.
A1  - Colafrancesco, Sergio
A1  - Cologna, Gabriele
A1  - Conrad, Jan
A1  - Couturier, C.
A1  - Cui, Y.
A1  - Dalton, M.
A1  - Daniel, Michael K.
A1  - Davids, I. D.
A1  - Degrange, B.
A1  - Deil, C.
A1  - deWilt, P.
A1  - Dickinson, H. J.
A1  - Djannati-Ataï, A.
A1  - Domainko, W.
A1  - Dubus, G.
A1  - Dutson, K.
A1  - Dyks, J.
A1  - Dyrda, M.
A1  - Edwards, T.
A1  - Egberts, Kathrin
A1  - Eger, P.
A1  - Espigat, P.
A1  - Farnier, C.
A1  - Fegan, S.
A1  - Feinstein, F.
A1  - Fernandes, M. V.
A1  - Fernandez, D.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Foerster, A.
A1  - Fuessling, M.
A1  - Gajdus, M.
A1  - Gallant, Y. A.
A1  - Garrigoux, T.
A1  - Giavitto, G.
A1  - Giebels, B.
A1  - Glicenstein, J. F.
A1  - Grondin, M. -H.
A1  - Grudzinska, M.
A1  - Haeffner, S.
A1  - Hahn, J.
A1  - Harris, J.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hervet, O.
A1  - Hillert, A.
A1  - Hinton, James Anthony
A1  - Hofmann, W.
A1  - Hofverberg, P.
A1  - Holler, M.
A1  - Horns, D.
A1  - Jacholkowska, A.
A1  - Jahn, C.
A1  - Jamrozy, Marek
A1  - Janiak, M.
A1  - Jankowsky, F.
A1  - Jung, I.
A1  - Kastendieck, M. A.
A1  - Katarzynski, Krzysztof
A1  - Katz, Uli
A1  - Kaufmann, S.
A1  - Khelifi, B.
A1  - Kieffer, M.
A1  - Klepser, S.
A1  - Klochkov, D.
A1  - Kluzniak, W.
A1  - Kneiske, T.
A1  - Kolitzus, D.
A1  - Komin, Nu.
A1  - Kosack, K.
A1  - Krakau, S.
A1  - Krayzel, F.
A1  - Krueger, P. P.
A1  - Laffon, H.
A1  - Lamanna, G.
A1  - Lefaucheur, J.
A1  - Lemiere, A.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J. -P.
A1  - Lennarz, D.
A1  - Lohse, T.
A1  - Lopatin, A.
A1  - Lu, C. -C.
A1  - Marandon, V.
A1  - Marcowith, Alexandre
A1  - Marx, R.
A1  - Maurin, G.
A1  - Maxted, N.
A1  - Mayer, M.
A1  - McComb, T. J. L.
A1  - Mehault, J.
A1  - Meintjes, P. J.
A1  - Menzler, U.
A1  - Meyer, M.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Moulin, Emmanuel
A1  - Murach, T.
A1  - Naumann, C. L.
A1  - de Naurois, M.
A1  - Niemiec, J.
A1  - Nolan, S. J.
A1  - Oakes, L.
A1  - Ohm, S.
A1  - Wilhelmi, E. de Ona
A1  - Opitz, B.
A1  - Ostrowski, M.
A1  - Oya, I.
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Arribas, M. Paz
A1  - Pekeur, N. W.
A1  - Pelletier, G.
A1  - Perez, J.
A1  - Petrucci, P. -O.
A1  - Peyaud, B.
A1  - Pita, S.
A1  - Poon, H.
A1  - Puehlhofer, G.
A1  - Punch, Michael
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Raue, M.
A1  - Reimer, A.
A1  - Reimer, Olaf
A1  - Renaud, M.
A1  - de los Reyes, R.
A1  - Rieger, F.
A1  - Rob, L.
A1  - Romoli, C.
A1  - Rosier-Lees, S.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Rulten, C. B.
A1  - Sahakian, V.
A1  - Sanchez, David M.
A1  - Santangelo, Andrea
A1  - Schlickeiser, R.
A1  - Schuessler, F.
A1  - Schulz, A.
A1  - Schwanke, U.
A1  - Schwarzburg, S.
A1  - Schwemmer, S.
A1  - Sol, H.
A1  - Spengler, G.
A1  - Spies, F.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Stinzing, F.
A1  - Stycz, K.
A1  - Sushch, Iurii
A1  - Szostek, A.
A1  - Tavernet, J. -P.
A1  - Tavernier, T.
A1  - Taylor, A. M.
A1  - Terrier, R.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Valerius, K.
A1  - van Eldik, Christopher
A1  - van Soelen, B.
A1  - Vasileiadis, G.
A1  - Venter, C.
A1  - Viana, A.
A1  - Vincent, P.
A1  - Vink, J.
A1  - Voelk, H. J.
A1  - Volpe, F.
A1  - Vorster, M.
A1  - Vuillaume, T.
A1  - Wagner, S. J.
A1  - Wagner, P.
A1  - Ward, M.
A1  - Weidinger, M.
A1  - Weitzel, Q.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Willmann, P.
A1  - Woernlein, A.
A1  - Wouters, D.
A1  - Zabalza, V.
A1  - Zacharias, M.
A1  - Zajczyk, A.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Zechlin, H. -S.
T1  - HESS J1640-465-an exceptionally luminous TeV gamma-ray supernova remnant
JF  - Monthly notices of the Royal Astronomical Society
N2  - The results of follow-up observations of the TeV gamma-ray source HESS J1640-465 from 2004 to 2011 with the High Energy Stereoscopic System (HESS) are reported in this work. The spectrum is well described by an exponential cut-off power law with photon index Gamma = 2.11 +/- 0.09(stat) +/- 0.10(sys), and a cut-off energy of E-2 = 6.0(-1.2)(+2.0) TeV. The TeV emission is significantly extended and overlaps with the northwestern part of the shell of the SNR G338.3-0.0. The new HESS results, a re-analysis of archival XMM-Newton data and multiwavelength observations suggest that a significant part of the gamma-ray emission from HESS J1640-465 originates in the supernova remnant shell. In a hadronic scenario, as suggested by the smooth connection of the GeV and TeV spectra, the product of total proton energy and mean target density could be as high as W(p)n(H) similar to 4 x 10(52)(d/10kpc)(2) erg cm(-3).
KW  - radiation mechanisms: non-thermal
KW  - ISM: individual objects: G338.3-0.0
KW  - ISM: supernova remnants
Y1  - 2014
U6  - https://doi.org/10.1093/mnras/stu139
SN  - 0035-8711
SN  - 1365-2966
VL  - 439
IS  - 3
SP  - 2828
EP  - 2836
PB  - Oxford Univ. Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Abramowski, Attila
A1  - Aharonian, Felix A.
A1  - Benkhali, Faical  Ait
A1  - Akhperjanian, A. G.
A1  - Angüner, Ekrem Oǧuzhan
A1  - Backes, Michael
A1  - Balenderan, Shangkari
A1  - Balzer, Arnim
A1  - Barnacka, Anna
A1  - Becherini, Yvonne
A1  - Tjus, J. Becker
A1  - Berge, David
A1  - Bernhard, Sabrina
A1  - Bernlöhr, K.
A1  - Birsin, E.
A1  - Biteau, Jonathan
A1  - Boettcher, Markus
A1  - Boisson, Catherine
A1  - Bolmont, J.
A1  - Bordas, Pol
A1  - Bregeon, Johan
A1  - Brun, Francois
A1  - Brun, Pierre
A1  - Bryan, Mark
A1  - Bulik, Tomasz
A1  - Carrigan, Svenja
A1  - Casanova, Sabrina
A1  - Chadwick, Paula M.
A1  - Chakraborty, N.
A1  - Chalme-Calvet, R.
A1  - Chaves, Ryan C. G.
A1  - Chretien, M.
A1  - Colafrancesco, Sergio
A1  - Cologna, Gabriele
A1  - Conrad, Jan
A1  - Couturier, C.
A1  - Cui, Y.
A1  - Davids, I. D.
A1  - Degrange, B.
A1  - Deil, C.
A1  - deWilt, P.
A1  - Djannati-Ataï, A.
A1  - Domainko, W.
A1  - Donath, A.
A1  - Dubus, G.
A1  - Dutson, K.
A1  - Dyks, J.
A1  - Dyrda, M.
A1  - Edwards, T.
A1  - Egberts, Kathrin
A1  - Eger, P.
A1  - Espigat, P.
A1  - Farnier, C.
A1  - Fegan, S.
A1  - Feinstein, F.
A1  - Fernandes, M. V.
A1  - Fernandez, D.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Foerster, A.
A1  - Fuessling, M.
A1  - Gabici, S.
A1  - Gajdus, M.
A1  - Gallant, Y. A.
A1  - Garrigoux, T.
A1  - Giavitto, G.
A1  - Giebels, B.
A1  - Glicenstein, J. F.
A1  - Gottschall, D.
A1  - Grondin, M. -H.
A1  - Grudzinska, M.
A1  - Hadasch, D.
A1  - Haeffner, S.
A1  - Hahn, J.
A1  - Harris, J.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hervet, O.
A1  - Hillert, A.
A1  - Hinton, James Anthony
A1  - Hofmann, W.
A1  - Hofverberg, P.
A1  - Holler, Margitte
A1  - Horns, D.
A1  - Ivascenko, A.
A1  - Jacholkowska, A.
A1  - Jahn, C.
A1  - Jamrozy, M.
A1  - Janiak, M.
A1  - Jankowsky, F.
A1  - Jung-Richardt, I.
A1  - Kastendieck, M. A.
A1  - Katarzynski, K.
A1  - Katz, U.
A1  - Kaufmann, S.
A1  - Khelifi, B.
A1  - Kieffer, M.
A1  - Klepser, S.
A1  - Klochkov, D.
A1  - Kluzniak, W.
A1  - Kolitzus, D.
A1  - Komin, Nu
A1  - Kosack, K.
A1  - Krakau, S.
A1  - Krayzel, F.
A1  - Krueger, P. P.
A1  - Laffon, H.
A1  - Lamanna, G.
A1  - Lefaucheur, J.
A1  - Lefranc, V.
A1  - Lemiere, A.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J. -P.
A1  - Lohse, T.
A1  - Lopatin, A.
A1  - Lu, C. -C.
A1  - Marandon, V.
A1  - Marcowith, Alexandre
A1  - Marx, R.
A1  - Maurin, G.
A1  - Maxted, N.
A1  - Mayer, Michael
A1  - McComb, T. J. L.
A1  - Mehault, J.
A1  - Meintjes, P. J.
A1  - Menzler, U.
A1  - Meyer, M.
A1  - Mitchell, A. M. W.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Mora, K.
A1  - Moulin, Emmanuel
A1  - Murach, T.
A1  - de Naurois, M.
A1  - Niemiec, J.
A1  - Nolan, S. J.
A1  - Oakes, L.
A1  - Odaka, H.
A1  - Ohm, S.
A1  - Opitz, B.
A1  - Ostrowski, M.
A1  - Oya, I.
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Arribas, M. Paz
A1  - Pekeur, N. W.
A1  - Pelletier, G.
A1  - Petrucci, P. -O.
A1  - Peyaud, B.
A1  - Pita, S.
A1  - Poon, H.
A1  - Puehlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Reichardt, I.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Renaud, M.
A1  - de los Reyes, R.
A1  - Rieger, F.
A1  - Romoli, C.
A1  - Rosier-Lees, S.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Rulten, C. B.
A1  - Sahakian, V.
A1  - Salek, D.
A1  - Sanchez, David M.
A1  - Santangelo, Andrea
A1  - Schlickeiser, R.
A1  - Schuessler, F.
A1  - Schulz, A.
A1  - Schwanke, U.
A1  - Schwarzburg, S.
A1  - Schwemmer, S.
A1  - Sol, H.
A1  - Spanier, F.
A1  - Spengler, G.
A1  - Spies, F.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Stinzing, F.
A1  - Stycz, K.
A1  - Sushch, Iurii
A1  - Tavernet, J. -P.
A1  - Tavernier, T.
A1  - Taylor, A. M.
A1  - Terrier, R.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Valerius, K.
A1  - van Eldik, C.
A1  - van Soelen, B.
A1  - Vasileiadis, G.
A1  - Veh, J.
A1  - Venter, C.
A1  - Viana, A.
A1  - Vincent, P.
A1  - Vink, J.
A1  - Voelk, H. J.
A1  - Volpe, F.
A1  - Vorster, M.
A1  - Vuillaume, T.
A1  - Wagner, S. J.
A1  - Wagner, P.
A1  - Wagner, R. M.
A1  - Ward, M.
A1  - Weidinger, M.
A1  - Weitzel, Q.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Willmann, P.
A1  - Woernlein, A.
A1  - Wouters, D.
A1  - Yang, R.
A1  - Zabalza, V.
A1  - Zaborov, D.
A1  - Zacharias, M.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Zechlin, H. -S.
T1  - Constraints on an Annihilation Signal from a Core of Constant Dark Matter Density around the Milky Way Center with HESS
JF  - Physical review letters
N2  - An annihilation signal of dark matter is searched for from the central region of the Milky Way. Data acquired in dedicated on-off observations of the Galactic center region with H.E.S.S. are analyzed for this purpose. No significant signal is found in a total of similar to 9 h of on-off observations. Upper limits on the velocity averaged cross section, <sigma upsilon >, for the annihilation of dark matter particles with masses in the range of similar to 300 GeV to similar to 10 TeV are derived. In contrast to previous constraints derived from observations of the Galactic center region, the constraints that are derived here apply also under the assumption of a central core of constant dark matter density around the center of the Galaxy. Values of <sigma upsilon > that are larger than 3 x 10(-24) cm(3)/s are excluded for dark matter particles with masses between similar to 1 and similar to 4 TeV at 95% C.L. if the radius of the central dark matter density core does not exceed 500 pc. This is the strongest constraint that is derived on <sigma upsilon > for annihilating TeV mass dark matter without the assumption of a centrally cusped dark matter density distribution in the search region.
Y1  - 2015
U6  - https://doi.org/10.1103/PhysRevLett.114.081301
SN  - 0031-9007
SN  - 1079-7114
VL  - 114
IS  - 8
PB  - American Physical Society
CY  - College Park
ER  - 
TY  - JOUR
A1  - Abramowski, Attila
A1  - Aharonian, Felix A.
A1  - Benkhali, Faical  Ait
A1  - Akhperjanian, A. G.
A1  - Angüner, Ekrem Oǧuzhan
A1  - Backes, Michael
A1  - Balenderan, Shangkari
A1  - Balzer, Arnim
A1  - Barnacka, Anna
A1  - Becherini, Yvonne
A1  - Tjus, J. Becker
A1  - Berge, David
A1  - Bernhard, Sabrina
A1  - Bernlöhr, K.
A1  - Birsin, E.
A1  - Biteau, Jonathan
A1  - Boettcher, Markus
A1  - Boisson, Catherine
A1  - Bolmont, J.
A1  - Bordas, Pol
A1  - Bregeon, Johan
A1  - Brun, Francois
A1  - Brun, Pierre
A1  - Bryan, Mark
A1  - Bulik, Tomasz
A1  - Carrigan, Svenja
A1  - Casanova, Sabrina
A1  - Chadwick, Paula M.
A1  - Chakraborty, N.
A1  - Chalme-Calvet, R.
A1  - Chaves, Ryan C. G.
A1  - Chretien, M.
A1  - Colafrancesco, Sergio
A1  - Cologna, Gabriele
A1  - Conrad, Jan
A1  - Couturier, C.
A1  - Cui, Y.
A1  - Davids, I. D.
A1  - Degrange, B.
A1  - Deil, C.
A1  - dewilt, P.
A1  - Djannati-Ataï, A.
A1  - Domainko, W.
A1  - Donath, A.
A1  - Dubus, G.
A1  - Dutson, K.
A1  - Dyks, J.
A1  - Dyrda, M.
A1  - Edwards, T.
A1  - Egberts, Kathrin
A1  - Eger, P.
A1  - Espigat, P.
A1  - Farnier, C.
A1  - Fegan, S.
A1  - Feinstein, F.
A1  - Fernandes, M. V.
A1  - Fernandez, D.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Foerster, A.
A1  - Fuessling, M.
A1  - Gabici, S.
A1  - Gajdus, M.
A1  - Gallant, Y. A.
A1  - Garrigoux, T.
A1  - Giavitto, G.
A1  - Giebels, B.
A1  - Glicenstein, J. F.
A1  - Gottschall, D.
A1  - Grondin, M. -H.
A1  - Grudzinska, M.
A1  - Hadasch, D.
A1  - Haeffner, S.
A1  - Hahn, J.
A1  - Harris, J.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hervet, O.
A1  - Hillert, A.
A1  - Hinton, James Anthony
A1  - Hofmann, W.
A1  - Hofverberg, P.
A1  - Holler, M.
A1  - Horns, D.
A1  - Ivascenko, A.
A1  - Jacholkowska, A.
A1  - Jahn, C.
A1  - Jamrozy, Marek
A1  - Janiak, M.
A1  - Jankowsky, F.
A1  - Jung-Richardt, I.
A1  - Kastendieck, M. A.
A1  - Katarzynski, Krzysztof
A1  - Katz, Uli
A1  - Kaufmann, S.
A1  - Khelifi, B.
A1  - Kieffer, M.
A1  - Klepser, S.
A1  - Klochkov, D.
A1  - Kluzniak, W.
A1  - Kolitzus, D.
A1  - Komin, Nu.
A1  - Kosack, K.
A1  - Krakau, S.
A1  - Krayzel, F.
A1  - Krueger, P. P.
A1  - Laffon, H.
A1  - Lamanna, G.
A1  - Lefaucheur, J.
A1  - Lefranc, V.
A1  - Lemiere, A.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J. -P.
A1  - Lohse, T.
A1  - Lopatin, A.
A1  - Lu, C. -C.
A1  - Marandon, V.
A1  - Marcowith, Alexandre
A1  - Marx, R.
A1  - Maurin, G.
A1  - Maxted, N.
A1  - Mayer, M.
A1  - McComb, T. J. L.
A1  - Mehault, J.
A1  - Meintjes, P. J.
A1  - Menzler, U.
A1  - Meyer, M.
A1  - Mitchell, A. M. W.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Mora, K.
A1  - Moulin, Emmanuel
A1  - Murach, T.
A1  - de Naurois, M.
A1  - Niemiec, J.
A1  - Nolan, S. J.
A1  - Oakes, L.
A1  - Odaka, H.
A1  - Ohm, S.
A1  - Opitz, B.
A1  - Ostrowski, M.
A1  - Oya, I.
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Arribas, M. Paz
A1  - Pekeur, N. W.
A1  - Pelletier, G.
A1  - Petrucci, P. -O.
A1  - Peyaud, B.
A1  - Pita, S.
A1  - Poon, H.
A1  - Puehlhofer, G.
A1  - Punch, Michael
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Reichardt, I.
A1  - Reimer, A.
A1  - Reimer, Olaf
A1  - Renaud, M.
A1  - de los Reyes, R.
A1  - Rieger, F.
A1  - Romoli, C.
A1  - Rosier-Lees, S.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Rulten, C. B.
A1  - Sahakian, V.
A1  - Salek, D.
A1  - Sanchez, David M.
A1  - Santangelo, Andrea
A1  - Schlickeiser, R.
A1  - Schuessler, Fabian
A1  - Schulz, A.
A1  - Schwanke, U.
A1  - Schwarzburg, S.
A1  - Schwemmer, S.
A1  - Sol, H.
A1  - Spanier, F.
A1  - Spengler, G.
A1  - Spies, F.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Stinzing, F.
A1  - Stycz, K.
A1  - Sushch, Iurii
A1  - Tavernet, J. -P.
A1  - Tavernier, T.
A1  - Taylor, A. M.
A1  - Terrier, R.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Valerius, K.
A1  - van Eldik, Christopher
A1  - van Soelen, B.
A1  - Vasileiadis, G.
A1  - Veh, J.
A1  - Venter, C.
A1  - Viana, A.
A1  - Vincent, P.
A1  - Vink, J.
A1  - Voelk, H. J.
A1  - Volpe, F.
A1  - Vorster, M.
A1  - Vuillaume, T.
A1  - Wagner, S. J.
A1  - Wagner, P.
A1  - Wagner, R. M.
A1  - Ward, M.
A1  - Weidinger, M.
A1  - Weitzel, Q.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Willmann, P.
A1  - Woernlein, A.
A1  - Wouters, D.
A1  - Yang, R.
A1  - Zabalza, V.
A1  - Zaborov, D.
A1  - Zacharias, M.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Zechlin, H. -S.
A1  - Fukui, Y.
T1  - Diffuse Galactic gamma-ray emission with HESS
JF  - Physical review : D, Particles, fields, gravitation, and cosmology
N2  - Diffuse gamma-ray emission is the most prominent observable signature of celestial cosmic-ray interactions at high energies. While already being investigated at GeVenergies over several decades, assessments of diffuse gamma-ray emission at TeVenergies remain sparse. After completion of the systematic survey of the inner Galaxy, the H.E.S.S. experiment is in a prime position to observe large-scale diffuse emission at TeVenergies. Data of the H.E.S.S. Galactic Plane Survey are investigated in regions off known gamma-ray sources. Corresponding gamma-ray flux measurements were made over an extensive grid of celestial locations. Longitudinal and latitudinal profiles of the observed gamma-ray fluxes show characteristic excess emission not attributable to known gamma-ray sources. For the first time large-scale gamma-ray emission along the Galactic plane using imaging atmospheric Cherenkov telescopes has been observed. While the background subtraction technique limits the ability to recover modest variation on the scale of the H.E.S.S. field of view or larger, which is characteristic of the inverse Compton scatter-induced Galactic diffuse emission, contributions of neutral pion decay as well as emission from unresolved gamma-ray sources can be recovered in the observed signal to a large fraction. Calculations show that the minimum gamma-ray emission from pi(0) decay represents a significant contribution to the total signal. This detection is interpreted as a mix of diffuse Galactic gamma-ray emission and unresolved sources.
Y1  - 2014
U6  - https://doi.org/10.1103/PhysRevD.90.122007
SN  - 1550-7998
SN  - 1550-2368
VL  - 90
IS  - 12
PB  - American Physical Society
CY  - College Park
ER  - 
TY  - JOUR
A1  - Abramowski, Attila
A1  - Aharonian, Felix A.
A1  - Benkhali, Faical  Ait
A1  - Akhperjanian, A. G.
A1  - Angüner, Ekrem Oǧuzhan
A1  - Backes, Michael
A1  - Balenderan, Shangkari
A1  - Balzer, Arnim
A1  - Barnacka, Anna
A1  - Becherini, Yvonne
A1  - Tjus, J. Becker
A1  - Berge, David
A1  - Bernhard, Sabrina
A1  - Bernlöhr, K.
A1  - Birsin, E.
A1  - Biteau, Jonathan
A1  - Boettcher, Markus
A1  - Boisson, Catherine
A1  - Bolmont, J.
A1  - Bordas, Pol
A1  - Bregeon, Johan
A1  - Brun, Francois
A1  - Brun, Pierre
A1  - Bryan, Mark
A1  - Bulik, Tomasz
A1  - Carrigan, Svenja
A1  - Casanova, Sabrina
A1  - Chadwick, Paula M.
A1  - Chakraborty, N.
A1  - Chalme-Calvet, R.
A1  - Chaves, Ryan C. G.
A1  - Chretien, M.
A1  - Colafrancesco, Sergio
A1  - Cologna, Gabriele
A1  - Conrad, Jan
A1  - Couturier, C.
A1  - Cui, Y.
A1  - Davids, I. D.
A1  - Degrange, B.
A1  - Deil, C.
A1  - deWilt, P.
A1  - Djannati-Ataï, A.
A1  - Domainko, W.
A1  - Donath, A.
A1  - Dubus, G.
A1  - Dutson, K.
A1  - Dyks, J.
A1  - Dyrda, M.
A1  - Edwards, T.
A1  - Egberts, Kathrin
A1  - Eger, P.
A1  - Espigat, P.
A1  - Farnier, C.
A1  - Fegan, S.
A1  - Feinstein, F.
A1  - Fernandes, M. V.
A1  - Fernandez, D.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Foerster, A.
A1  - Füssling, Matthias
A1  - Gabici, S.
A1  - Gajdus, M.
A1  - Gallant, Y. A.
A1  - Garrigoux, T.
A1  - Giavitto, G.
A1  - Giebels, B.
A1  - Glicenstein, J. F.
A1  - Gottschall, D.
A1  - Grondin, M. -H.
A1  - Grudzinska, M.
A1  - Hadasch, D.
A1  - Haeffner, S.
A1  - Hahn, J.
A1  - Harris, J.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hervet, O.
A1  - Hillert, A.
A1  - Hinton, James Anthony
A1  - Hofmann, W.
A1  - Hofverberg, P.
A1  - Holler, Maraike
A1  - Horns, D.
A1  - Ivascenko, A.
A1  - Jacholkowska, A.
A1  - Jahn, C.
A1  - Jamrozy, M.
A1  - Janiak, M.
A1  - Jankowsky, F.
A1  - Jung-Richardt, I.
A1  - Kastendieck, M. A.
A1  - Katarzynski, K.
A1  - Katz, U.
A1  - Kaufmann, S.
A1  - Khelifi, B.
A1  - Kieffer, M.
A1  - Klepser, S.
A1  - Klochkov, D.
A1  - Kluzniak, W.
A1  - Kolitzus, D.
A1  - Komin, Nu.
A1  - Kosack, K.
A1  - Krakau, S.
A1  - Krayzel, F.
A1  - Krueger, P. P.
A1  - Laffon, H.
A1  - Lamanna, G.
A1  - Lefaucheur, J.
A1  - Lefranc, V.
A1  - Lemiere, A.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J. -P.
A1  - Lohse, T.
A1  - Lopatin, A.
A1  - Lu, C. -C.
A1  - Marandon, V.
A1  - Marcowith, Alexandre
A1  - Marx, R.
A1  - Maurin, G.
A1  - Maxted, N.
A1  - Mayer, Michael
A1  - McComb, T. J. L.
A1  - Mehault, J.
A1  - Meintjes, P. J.
A1  - Menzler, U.
A1  - Meyer, M.
A1  - Mitchell, A. M. W.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Mora, K.
A1  - Moulin, Emmanuel
A1  - Murach, T.
A1  - de Naurois, M.
A1  - Niemiec, J.
A1  - Nolan, S. J.
A1  - Oakes, L.
A1  - Odaka, H.
A1  - Ohm, S.
A1  - Opitz, B.
A1  - Ostrowski, M.
A1  - Oya, I.
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Arribas, M. Paz
A1  - Pekeur, N. W.
A1  - Pelletier, G.
A1  - Petrucci, P. -O
A1  - Peyaud, B.
A1  - Pita, S.
A1  - Poon, H.
A1  - Puehlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Reichardt, I.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Renaud, M.
A1  - de los Reyes, R.
A1  - Rieger, F.
A1  - Romoli, C.
A1  - Rosier-Lees, S.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Rulten, C. B.
A1  - Sahakian, V.
A1  - Salek, D.
A1  - Sanchez, David M.
A1  - Santangelo, Andrea
A1  - Schlickeiser, R.
A1  - Schuessler, F.
A1  - Schulz, A.
A1  - Schwanke, U.
A1  - Schwarzburg, S.
A1  - Schwemmer, S.
A1  - Sol, H.
A1  - Spanier, F.
A1  - Spengler, G.
A1  - Spies, F.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Stinzing, F.
A1  - Stycz, K.
A1  - Sushch, Iurii
A1  - Tavernet, J. -P.
A1  - Tavernier, T.
A1  - Taylor, A. M.
A1  - Terrier, R.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Valerius, K.
A1  - van Eldik, C.
A1  - van Soelen, B.
A1  - Vasileiadis, G.
A1  - Veh, J.
A1  - Venter, C.
A1  - Viana, A.
A1  - Vincent, P.
A1  - Vink, J.
A1  - Voelk, H. J.
A1  - Volpe, F.
A1  - Vorster, M.
A1  - Vuillaume, T.
A1  - Wagner, S. J.
A1  - Wagner, P.
A1  - Wagner, R. M.
A1  - Ward, M.
A1  - Weidinger, M.
A1  - Weitzel, Q.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Willmann, P.
A1  - Woernlein, A.
A1  - Wouters, D.
A1  - Yang, R.
A1  - Zabalza, V.
A1  - Zaborov, D.
A1  - Zacharias, M.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Zechlin, H. -S.
T1  - HESS reveals a lack of TeV emission from the supernova remnant Puppis A (Research Note)
JF  - Astronomy and astrophysics : an international weekly journal
N2  - Context. Puppis A is an interesting similar to 4 kyr-old supernova remnant (SNR) that shows strong evidence of interaction between the forward shock and a molecular cloud. It has been studied in detail from radio frequencies to high-energy (HE, 0.1-100 GeV) gamma-rays. An analysis of the Fermi-LAT data has shown extended HE gamma-ray emission with a 0.2-100 GeV spectrum exhibiting no significant deviation from a power law, unlike most of the GeV-emitting SNRs known to be interacting with molecular clouds. This makes it a promising target for imaging atmospheric Cherenkov telescopes (IACTs) to probe the gamma-ray emission above 100 GeV.
 Aims. Very-high-energy (VHE, E >= 0.1 TeV) gamma-ray emission from Puppis A has been, for the first time, searched for with the High Energy Stereoscopic System (HESS.).
 Methods. Stereoscopic imaging of Cherenkov radiation from extensive air showers is used to reconstruct the direction and energy of the incident gamma-rays in order to produce sky images and source spectra. The profile likelihood method is applied to find constraints on the existence of a potential break or cutoff in the photon spectrum.
 Results. The analysis of the HESS. data does not reveal any significant emission towards Puppis A. The derived upper limits on the differential photon flux imply that its broadband gamma-ray spectrum must exhibit a spectral break or cutoff. By combining Fermi-LAT and HESS. measurements, the 99% confidence-level upper limits on such a cutoff are found to be 450 and 280 GeV, assuming a power law with a simple exponential and a sub-exponential cutoff, respectively. It is concluded that none of the standard limitations (age, size, radiative losses) on the particle acceleration mechanism, assumed to be continuing at present, can explain the lack of VHE signal. The scenario in which particle acceleration has ceased some time ago is considered as an alternative explanation. The HE/VHE spectrum of Puppis A could then exhibit a break of non-radiative origin (as observed in several other interacting SNRs, albeit at somewhat higher energies), owing to the interaction with dense and neutral material, in particular towards the NE region.
KW  - gamma rays: ISM
KW  - ISM: individual objects: Puppis A
KW  - radiation mechanisms: non-thermal
KW  - cosmic rays
KW  - acceleration of particles
Y1  - 2015
U6  - https://doi.org/10.1051/0004-6361/2014424805
SN  - 0004-6361
SN  - 1432-0746
VL  - 575
PB  - EDP Sciences
CY  - Les Ulis
ER  - 
TY  - JOUR
A1  - Abdalla, Hassan E.
A1  - Abramowski, Attila
A1  - Aharonian, Felix A.
A1  - Benkhali, Faical  Ait
A1  - Akhperjanian, A. G.
A1  - Andersson, T.
A1  - Angüner, Ekrem Oǧuzhan
A1  - Arrieta, M.
A1  - Aubert, Pierre
A1  - Backes, Michael
A1  - Balzer, Arnim
A1  - Barnard, Michelle
A1  - Becherini, Yvonne
A1  - Tjus, J. Becker
A1  - Berge, David
A1  - Bernhard, Sabrina
A1  - Bernlöhr, K.
A1  - Birsin, E.
A1  - Blackwell, R.
A1  - Boettcher, Markus
A1  - Boisson, Catherine
A1  - Bolmont, J.
A1  - Bordas, Pol
A1  - Bregeon, Johan
A1  - Brun, Francois
A1  - Brun, Pierre
A1  - Bryan, Mark
A1  - Bulik, Tomasz
A1  - Capasso, M.
A1  - Carr, John
A1  - Casanova, Sabrina
A1  - Chakraborty, N.
A1  - Chalme-Calvet, R.
A1  - Chaves, Ryan C. G.
A1  - Chen, Andrew
A1  - Chevalier, J.
A1  - Chretien, M.
A1  - Colafrancesco, Sergio
A1  - Cologna, Gabriele
A1  - Condon, B.
A1  - Conrad, Jan
A1  - Couturier, C.
A1  - Cui, Y.
A1  - Davids, I. D.
A1  - Degrange, B.
A1  - Deil, C.
A1  - Devin, J.
A1  - de Wilt, P.
A1  - Djannati-Ataie, A.
A1  - Domainko, W.
A1  - Donath, A.
A1  - Dubus, G.
A1  - Dutson, K.
A1  - Dyks, J.
A1  - Dyrda, M.
A1  - Edwards, T.
A1  - Egberts, Kathrin
A1  - Eger, P.
A1  - Ernenwein, J. -P.
A1  - Eschbach, S.
A1  - Farnier, C.
A1  - Fegan, S.
A1  - Fernandes, M. V.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Foerster, A.
A1  - Funk, S.
A1  - Fuessling, M.
A1  - Gabici, S.
A1  - Gajdus, M.
A1  - Gallant, Y. A.
A1  - Garrigoux, T.
A1  - Giavitto, G.
A1  - Giebels, B.
A1  - Glicenstein, J. F.
A1  - Gottschall, D.
A1  - Goyal, A.
A1  - Grondin, M. -H.
A1  - Grudzinska, M.
A1  - Hadasch, D.
A1  - Hahn, J.
A1  - Hawkes, J.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hervet, O.
A1  - Hillert, A.
A1  - Hinton, James Anthony
A1  - Hofmann, W.
A1  - Hoischen, Clemens
A1  - Holler, M.
A1  - Horns, D.
A1  - Ivascenko, A.
A1  - Jacholkowska, A.
A1  - Jamrozy, M.
A1  - Janiak, M.
A1  - Jankowsky, D.
A1  - Jankowsky, F.
A1  - Jingo, M.
A1  - Jogler, T.
A1  - Jouvin, L.
A1  - Jung-Richardt, I.
A1  - Kastendieck, M. A.
A1  - Katarzynski, K.
A1  - Katz, U.
A1  - Kerszberg, D.
A1  - Khelifi, B.
A1  - Kieffer, M.
A1  - King, J.
A1  - Klepser, S.
A1  - Klochkov, D.
A1  - Kluzniak, W.
A1  - Kolitzus, D.
A1  - Komin, Nu.
A1  - Kosack, K.
A1  - Krakau, S.
A1  - Kraus, M.
A1  - Krayzel, F.
A1  - Krueger, P. P.
A1  - Laffon, H.
A1  - Lamanna, G.
A1  - Lau, J.
A1  - Lees, J. -P.
A1  - Lefaucheur, J.
A1  - Lefranc, V.
A1  - Lemiere, A.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J. -P.
A1  - Leser, Eva
A1  - Liu, R.
A1  - Lohse, T.
A1  - Lorentz, M.
A1  - Lypova, I.
A1  - Marandon, V.
A1  - Marcowith, Alexandre
A1  - Mariaud, C.
A1  - Marx, R.
A1  - Maurin, G.
A1  - Maxted, N.
A1  - Mayer, Michael
A1  - Meintjes, P. J.
A1  - Meyer, M.
A1  - Mitchell, A. M. W.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Mora, K.
A1  - Moulin, Emmanuel
A1  - Murach, T.
A1  - de Naurois, M.
A1  - Niederwanger, F.
A1  - Niemiec, J.
A1  - Oakes, L.
A1  - Odaka, H.
A1  - Ohm, S.
A1  - Ostrowski, M.
A1  - Oettl, S.
A1  - Oya, I.
A1  - Padovani, M.
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Arribas, M. Paz
A1  - Pekeur, N. W.
A1  - Pelletier, G.
A1  - Perennes, C.
A1  - Petrucci, P. -O.
A1  - Peyaud, B.
A1  - Pita, S.
A1  - Poon, H.
A1  - Prokhorov, D.
A1  - Prokoph, H.
A1  - Puehlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Renaud, M.
A1  - Reyes, R. de los
A1  - Rieger, F.
A1  - Romoli, C.
A1  - Rosier-Lees, S.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Rulten, C. B.
A1  - Sahakian, V.
A1  - Salek, D.
A1  - Sanchez, David M.
A1  - Santangelo, Andrea
A1  - Sasaki, M.
A1  - Schlickeiser, R.
A1  - Schuessler, F.
A1  - Schulz, A.
A1  - Schwanke, U.
A1  - Schwemmer, S.
A1  - Settimo, M.
A1  - Seyffert, A. S.
A1  - Shafi, N.
A1  - Shilon, I.
A1  - Simoni, R.
A1  - Sol, H.
A1  - Spanier, F.
A1  - Spengler, G.
A1  - Spies, F.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Stinzing, F.
A1  - Stycz, K.
A1  - Sushch, Iurii
A1  - Tavernet, J. -P.
A1  - Tavernier, T.
A1  - Taylor, A. M.
A1  - Terrier, R.
A1  - Tibaldo, L.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Tuffs, R.
A1  - van der Walt, J.
A1  - van Eldik, C.
A1  - van Soelen, B.
A1  - Vasileiadis, G.
A1  - Veh, J.
A1  - Venter, C.
A1  - Viana, A.
A1  - Vincent, P.
A1  - Vink, J.
A1  - Voisin, F.
A1  - Voelk, H. J.
A1  - Vuillaume, T.
A1  - Wadiasingh, Z.
A1  - Wagner, S. J.
A1  - Wagner, P.
A1  - Wagner, R. M.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Willmann, P.
A1  - Woernlein, A.
A1  - Wouters, D.
A1  - Yang, R.
A1  - Zabalza, V.
A1  - Zaborov, D.
A1  - Zacharias, M.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Zefi, F.
A1  - Ziegler, A.
A1  - Zywucka, N.
T1  - HESS Limits on Linelike Dark Matter Signatures in the 100 GeV to 2 TeV Energy Range Close to the Galactic Center
JF  - Physical review letters
N2  - A search for dark matter linelike signals iss performed in the vicinity of the Galactic Center by the H.E.S.S. experiment on observational data taken in 2014. An unbinned likelihood analysis iss developed to improve the sensitivity to linelike signals. The upgraded analysis along with newer data extend the energy coverage of the previous measurement down to 100 GeV. The 18 h of data collected with the H.E.S.S. array allow one to rule out at 95% C.L. the presence of a 130 GeV line (at l = -1.5 degrees, b = 0 degrees and for a dark matter profile centered at this location) previously reported in Fermi-LAT data. This new analysis overlaps significantly in energy with previous Fermi-LAT and H.E.S.S. results. No significant excess associated with dark matter annihilations was found in the energy range of 100 GeV to 2 TeV and upper limits on the gamma-ray flux and the velocity weighted annihilation cross section are derived adopting an Einasto dark matter halo profile. Expected limits for present and future large statistics H.E.S.S. observations are also given.
Y1  - 2016
U6  - https://doi.org/10.1103/PhysRevLett.117.151302
SN  - 0031-9007
SN  - 1079-7114
VL  - 117
PB  - American Physical Society
CY  - College Park
ER  - 
TY  - JOUR
A1  - Förstner, Bernd R.
A1  - Tschorn, Mira
A1  - Reinoso-Schiller, Nicolas
A1  - Maričić, Lea Mascarell
A1  - Röcher, Erik
A1  - Kalman, Janos L.
A1  - Stroth, Sanna
A1  - Mayer, Annalina V.
A1  - Schwarz, Kristina
A1  - Kaiser, Anna
A1  - Pfennig, Andrea
A1  - Manook, André
A1  - Ising, Marcus
A1  - Heinig, Ingmar
A1  - Pittig, Andre
A1  - Heinz, Andreas
A1  - Mathiak, Klaus
A1  - Schulze, Thomas G.
A1  - Schneider, Frank
A1  - Kamp-Becker, Inge
A1  - Meyer-Lindenberg, Andreas
A1  - Padberg, Frank
A1  - Banaschewski, Tobias
A1  - Bauer, Michael
A1  - Rupprecht, Rainer
A1  - Wittchen, Hans-Ulrich
A1  - Rapp, Michael A.
T1  - Mapping research domain criteria using a transdiagnostic mini-RDoC assessment in mental disorders: a confirmatory factor analysis
JF  - European archives of psychiatry and clinical neuroscience
N2  - This study aimed to build on the relationship of well-established self-report and behavioral assessments to the latent constructs positive (PVS) and negative valence systems (NVS), cognitive systems (CS), and social processes (SP) of the Research Domain Criteria (RDoC) framework in a large transnosological population which cuts across DSM/ICD-10 disorder criteria categories. One thousand four hundred and thirty one participants (42.1% suffering from anxiety/fear-related, 18.2% from depressive, 7.9% from schizophrenia spectrum, 7.5% from bipolar, 3.4% from autism spectrum, 2.2% from other disorders, 18.4% healthy controls, and 0.2% with no diagnosis specified) recruited in studies within the German research network for mental disorders for the Phenotypic, Diagnostic and Clinical Domain Assessment Network Germany (PD-CAN) were examined with a Mini-RDoC-Assessment including behavioral and self-report measures. The respective data was analyzed with confirmatory factor analysis (CFA) to delineate the underlying latent RDoC-structure. A revised four-factor model reflecting the core domains positive and negative valence systems as well as cognitive systems and social processes showed a good fit across this sample and showed significantly better fit compared to a one factor solution. The connections between the domains PVS, NVS and SP could be substantiated, indicating a universal latent structure spanning across known nosological entities. This study is the first to give an impression on the latent structure and intercorrelations between four core Research Domain Criteria in a transnosological sample. We emphasize the possibility of using already existing and well validated self-report and behavioral measurements to capture aspects of the latent structure informed by the RDoC matrix.
KW  - Diagnosis and classification
KW  - Research Domain Criteria
KW  - PD-CAN
KW  - Confirmatory factor analysis CFA
KW  - RDoC
KW  - Transdiagnostic
Y1  - 2022
U6  - https://doi.org/10.1007/s00406-022-01440-6
SN  - 0940-1334
SN  - 1433-8491
VL  - 273
IS  - 3
SP  - 527
EP  - 539
PB  - Springer Nature
CY  - Heidelberg
ER  - 
TY  - JOUR
A1  - Pehlivanoglu, Tuna
A1  - Würtz-Kozak, Karin
A1  - Heider, Franziska
A1  - Sauer, Daniel
A1  - Wanke-Jellinek, Lorenz
A1  - Mayer, Michael
A1  - Mehren, Christoph
T1  - Clinical and Radiographic Outcome of Patients With Cervical Spondylotic Myelopathy Undergoing Total Disc Replacement
JF  - SPINE
N2  - Study Design. A nonrandomized, prospective, and single-center clinical trial. Objective. The aim of this study was to investigate the clinical and radiographic efficacy of ProDisc Vivo cervical total disc replacement (cTDR) in patients with clinical and radiographic documented cervical spondylotic myelopathy (CSM), due to degenerative changes at the index level. Summary of Background Data. Decompression and fusion is still the gold standard in patients with cervical myelopathy. Very limited data are available regarding the application of cTDR in patients with clinical and radiological documented CSM in context of clinical and radiographic outcomes. Methods. Clinical outcome scores included the Neck Disability Index (NDI), Visual Analogue Scale (VAS), arm and neck pain self-assessment questionnaires as well as the Nurick grade and the Japanese Orthopaedic Association (JOA) score. The radiological outcome included the range of motion (ROM), the segmental and global (C2-C7) lordosis, and the occurrence of heterotopic ossifications. Results. Eighteen consecutive patients (10 males, 8 females) with documented clinical and radiological signs of myelopathy were included in this investigation. The study population had a mean age of 52.4 years and a follow-up period of 20.3 months in average (range 3-48 months). The mean range ROM of the index level stayed consistent with 6.8 degrees preoperatively and 7.2 degrees (P = 0.578) at the last follow-up; the global lordosis in neutral position changed from 3.5 degrees to 14.2 degrees significantly (P = 0.005) in mean. The JOA score improved from 11.3 to 16.6 (P < 0.001) as well as the NDI 36.7 to 10.3 (P < 0.001) and the VAS score from 5.7/6.1 (arm/neck) to 1.3/2.0 (P P < 0.001). The mean Nurick grade was 1.33 preoperatively and dropped down in all cases to Nurick grade of 0 (P < 0.001). Conclusion. cTDR (with ProDisc Vivio) in patients with CSM yielded good clinical and radiographic outcomes and found as a reliable, safe, and motion-preserving surgical treatment option, although its indication is very limited due to numerous exclusion criteria.
KW  - cervical myelopathy
KW  - cervical total disc replacement
KW  - disc arthroplasty
KW  - ProDisc Vivo
Y1  - 2019
U6  - https://doi.org/10.1097/BRS.0000000000003079
SN  - 0362-2436
SN  - 1528-1159
VL  - 44
IS  - 20
SP  - 1403
EP  - 1411
PB  - Lippincott Williams & Wilkins
CY  - Philadelphia
ER  - 
TY  - JOUR
A1  - Kastl, Johanna
A1  - Braun, Joachim
A1  - Prestel, Andreas
A1  - Möller, Heiko Michael
A1  - Huhn, Thomas
A1  - Mayer, Thomas U.
T1  - Mad2 Inhibitor-1 (M2I-1): A Small Molecule Protein-Protein Interaction Inhibitor Targeting the Mitotic Spindle Assembly Checkpoint
JF  - ACS chemical biology
N2  - The genetic integrity of each organism depends on the faithful segregation of its genome during mitosis. To meet this challenge, a cellular surveillance mechanism, termed the spindle assembly checkpoint (SAC), evolved that monitors the correct attachment of chromosomes and blocks progression through mitosis if corrections are needed. While the central role of the SAC for genome integrity is well established, its functional dissection has been hampered by the limited availability of appropriate small molecule inhibitors. Using a fluorescence polarization-based screen, we identify Mad2 inhibitor-1 (M2I-1), the first small molecule inhibitor targeting the binding of Mad2 to Cdc20, an essential protein-protein interaction (PPI) within the SAC. Based on computational and biochemical analyses, we propose that M2I-1 disturbs conformational dynamics of Mad2 critical for complex formation with Cdc20. Cellular studies revealed that M2I-1 weakens the SAC response, indicating that the compound might be active in cells. Thus, our study identifies the SAC specific complex formation between Mad2 and Cdc20 as a protein-protein interaction that can be targeted by small molecules.
Y1  - 2015
U6  - https://doi.org/10.1021/acschembio.5b00121
SN  - 1554-8929
SN  - 1554-8937
VL  - 10
IS  - 7
SP  - 1661
EP  - 1666
PB  - American Chemical Society
CY  - Washington
ER  - 
TY  - JOUR
A1  - Vorburger, Thomas
A1  - Nedielkov, Ruslan
A1  - Brosig, Alexander
A1  - Bok, Eva
A1  - Schunke, Emina
A1  - Steffen, Wojtek
A1  - Mayer, Sonja
A1  - Goetz, Friedrich
A1  - Möller, Heiko Michael
A1  - Steuber, Julia
T1  - Role of the Na+-translocating NADH:quinone oxidoreductase in voltage generation and Na+ extrusion in Vibrio cholerae
JF  - Biochimica et biophysica acta : Bioenergetics
N2  - For Vibrio cholerae, the coordinated import and export of Na+ is crucial for adaptation to habitats with different osmolarities. We investigated the Na+-extruding branch of the sodium cycle in this human pathogen by in vivo Na-23-NMR spectroscopy. The Na+ extrusion activity of cells was monitored after adding glucose which stimulated respiration via the Na+-translocating NADH:quinone oxidoreductase (Na+-NQR). In a V. cholerae deletion mutant devoid of the Na+-NQR encoding genes (nqrA-F), rates of respiratory Na+ extrusion were decreased by a factor of four, but the cytoplasmic Na+ concentration was essentially unchanged. Furthermore, the mutant was impaired in formation of transmembrane voltage (Delta psi, inside negative) and did not grow under hypoosmotic conditions at pH 8.2 or above. This growth defect could be complemented by transformation with the plasmid encoded nqr operon. In an alkaline environment, Na+/H+ antiporters acidify the cytoplasm at the expense of the transmembrane voltage. It is proposed that, at alkaline pH and limiting Na+ concentrations, the Na+-NQR is crucial for generation of a transmembrane voltage to drive the import of H+ by electrogenic Na+/H+ antiporters. Our study provides the basis to understand the role of the Na+-NQR in pathogenicity of V. cholerae and other pathogens relying on this primary Na+ pump for respiration. (C) 2015 Elsevier B.V. All rights reserved.
KW  - Nuclear magnetic resonance (NMR)
KW  - Sodium transport
KW  - Vibrio cholerae
KW  - Respiration
KW  - Na+ homeostasis
KW  - Hypoosmotic stress
Y1  - 2016
U6  - https://doi.org/10.1016/j.bbabio.2015.12.010
SN  - 0005-2728
SN  - 0006-3002
VL  - 1857
SP  - 473
EP  - 482
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Risch, Lucie
A1  - Cassel, Michael
A1  - Mayer, Frank
T1  - Acute effect of running exercise on physiological Achilles tendon blood flow
JF  - Scandinavian journal of medicine & science in sports
N2  - Sonographically detectable intratendinous blood flow (IBF) is found in 50%-88% of Achilles tendinopathy patients as well as in up to 35% of asymptomatic Achilles tendons (AT). Although IBF is frequently associated with tendon pathology, it may also represent a physiological regulation, for example, due to increased blood flow in response to exercise. Therefore, this study aimed to investigate the acute effects of a standardized running exercise protocol on IBF assessed with Doppler ultrasound (DU) Advanced dynamic flow in healthy ATs. 10 recreationally active adults (5 f, 5m; 29 +/- 3years, 1.72 +/- 0.12m, 68 +/- 16kg, physical activity 206 +/- 145minute/wk) with no history of AT pain and inconspicious tendon structure performed 3 treadmill running tasks on separate days (M1-3) with DU examinations directly before and 5, 30, 60, and 120minutes after exercise. At M1, an incremental exercise test was used to determine the individual anaerobic threshold (IAT). At M2 and M3, participants performed 30-minute submaximal constant load tests (CL1/CL2) with an intensity 5% below IAT. IBF in each tendon was quantified by counting the number of vessels. IBF increased in five ATs from no vessels at baseline to one to four vessels solely detectable 5minutes after CL1 or CL2. One AT had persisting IBF (three vessels) throughout all examinations. Fourteen ATs revealed no IBF at all. Prolonged running led to a physiological, temporary appearance of IBF in 25% of asymptomatic ATs. To avoid exercise-induced IBF in clinical practice, DU examinations should be performed after 30minutes of rest.
KW  - advanced dynamic flow
KW  - doppler ultrasound
KW  - hyperemia
KW  - neovascularization
KW  - sonography
Y1  - 2017
U6  - https://doi.org/10.1111/sms.12874
SN  - 0905-7188
SN  - 1600-0838
VL  - 28
IS  - 1
SP  - 138
EP  - 143
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - GEN
A1  - Rauscher, Larissa
A1  - Kohn, Juliane
A1  - Käser, Tanja
A1  - Mayer, Verena
A1  - Kucian, Karin
A1  - McCaskey, Ursina
A1  - Esser, Günter
A1  - von Aster, Michael G.
T1  - Evaluation of a computer-based training program for enhancing arithmetic skills and spatial number representation in primary school children
T2  - Postprints der Universität Potsdam : Humanwissenschaftliche Reihe
N2  - Calcularis is a computer-based training program which focuses on basic numerical skills, spatial representation of numbers and arithmetic operations. The program includes a user model allowing flexible adaptation to the child's individual knowledge and learning profile. The study design to evaluate the training comprises three conditions (Calcularis group, waiting control group, spelling training group). One hundred and thirty-eight children from second to fifth grade participated in the study. Training duration comprised a minimum of 24 training sessions of 20 min within a time period of 6-8 weeks. Compared to the group without training (waiting control group) and the group with an alternative training (spelling training group), the children of the Calcularis group demonstrated a higher benefit in subtraction and number line estimation with medium to large effect sizes. Therefore, Calcularis can be used effectively to support children in arithmetic performance and spatial number representation.
T3  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 430 
KW  - numerical development
KW  - evaluative study
KW  - primary school
KW  - computer-based training
KW  - mathematics instruction
Y1  - 2018
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-406727
IS  - 430
ER  - 
TY  - JOUR
A1  - Rauscher, Larissa
A1  - Kohn, Juliane
A1  - Käser, Tanja
A1  - Mayer, Verena
A1  - Kucian, Karin
A1  - McCaskey, Ursina
A1  - Esser, Günter
A1  - von Aster, Michael G.
T1  - Evaluation of a Computer-Based Training Program for Enhancing Arithmetic Skills and Spatial Number Representation in Primary School Children
JF  - Frontiers in psychology
N2  - Calcularis is a computer-based training program which focuses on basic numerical skills, spatial representation of numbers and arithmetic operations. The program includes a user model allowing flexible adaptation to the child's individual knowledge and learning profile. The study design to evaluate the training comprises three conditions (Calcularis group, waiting control group, spelling training group). One hundred and thirty-eight children from second to fifth grade participated in the study. Training duration comprised a minimum of 24 training sessions of 20 min within a time period of 6–8 weeks. Compared to the group without training (waiting control group) and the group with an alternative training (spelling training group), the children of the Calcularis group demonstrated a higher benefit in subtraction and number line estimation with medium to large effect sizes. Therefore, Calcularis can be used effectively to support children in arithmetic performance and spatial number representation.
KW  - numerical development
KW  - evaluative study
KW  - primary school
KW  - computer-based training
KW  - mathematics instruction
Y1  - 2016
U6  - https://doi.org/10.3389/fpsyg.2016.00913
SN  - 1664-1078
VL  - 7
SP  - 14086
EP  - 14099
PB  - Frontiers Research Foundation
CY  - Lausanne
ER  - 
TY  - JOUR
A1  - Mayer, Magnus C.
A1  - Schauenburg, Linda
A1  - Thompson-Steckel, Greta
A1  - Dunsing, Valentin
A1  - Kaden, Daniela
A1  - Voigt, Philipp
A1  - Schaefer, Michael
A1  - Chiantia, Salvatore
A1  - Kennedy, Timothy E.
A1  - Multhaup, Gerhard
T1  - Amyloid precursor-like protein 1 (APLP1) exhibits stronger
zinc-dependent neuronal adhesion than amyloid precursor protein and
APLP2
JF  - Journal of neurochemistry
N2  - The amyloid precursor protein (APP) and its paralogs, amyloid precursor-like protein 1 (APLP1) and APLP2, are metalloproteins with a putative role both in synaptogenesis and in maintaining synapse structure. Here, we studied the effect of zinc on membrane localization, adhesion, and secretase cleavage of APP, APLP1, and APLP2 in cell culture and rat neurons. For this, we employed live-cell microscopy techniques, a microcontact printing adhesion assay and ELISA for protein detection in cell culture supernatants. We report that zinc induces the multimerization of proteins of the amyloid precursor protein family and enriches them at cellular adhesion sites. Thus, zinc facilitates the formation of de novo APP and APLP1 containing adhesion complexes, whereas it does not have such influence on APLP2. Furthermore, zinc-binding prevented cleavage of APP and APLPs by extracellular secretases. In conclusion, the complexation of zinc modulates neuronal functions of APP and APLPs by (i) regulating formation of adhesion complexes, most prominently for APLP1, and (ii) by reducing the concentrations of neurotrophic soluble APP/APLP ectodomains.
KW  - amyloid precursor protein
KW  - amyloid precursor-like protein
KW  - neuronal adhesion
KW  - number and brightness
KW  - zinc
Y1  - 2016
U6  - https://doi.org/10.1111/jnc.13540
SN  - 0022-3042
SN  - 1471-4159
VL  - 137
SP  - 266
EP  - 276
PB  - Wiley-Blackwell
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Lepetit, Petra
A1  - Viereck, Lothar
A1  - Piper, John D. A.
A1  - Sudo, Masafumi
A1  - Gurel, Ali
A1  - Copuroglu, Ibrahim
A1  - Gruber, Manuela
A1  - Mayer, Bernhard
A1  - Koch, Michael
A1  - Tatar, Orhan
A1  - Gursoy, Halil
T1  - Ar-40/Ar-39 dating of ignimbrites and plinian air-fall layers from Cappadocia, Central Turkey: Implications to chronostratigraphic and Eastern Mediterranean palaeoenvironmental record
JF  - Chemie der Erde : interdisciplinary journal for chemical problems of the geo-sciences and geo-ecology
N2  - Magmatism forming the Central Anatolian Volcanic Province of Cappadocia, central Turkey, records the last phase of Neotethyan subduction after similar to 11 Ma. Thirteen large calc-alkaline ignimbrite sheets form marker bands within the volcano-sedimentary succession (the Urgup Formation) and provide a robust chronostratigraphy for paleoecologic evaluation of the interleaved paleosols. This paper evaluates the chronologic record in the context of the radiometric, magnetostratigraphic and lithostratigraphic controls. Previous inconsistencies relating primarily to K/Ar evidence were reason for the initiation of an integrated study which includes Ar-40/Ar-39 dating, palaeomagnetic and stratigraphic evidence. The newly determined Ar-40/Ar-39-ages (Lepetit, 2010) are in agreement with Ar/Ar and U/Pb data meanwhile published by Pauquette and Le Pennec (2012) and Aydar et al. (2012). The Ar-40/Ar-39-ages restrict the end of the Urgup Formation to the late Miocene. The paleosol sequence enclosed by the ignimbrites is thus restricted to the late Miocene, the most intense formation of pedogene calcretes correlating with the Messinian Salinity Crisis.
KW  - Ar-40/Ar-39 dating
KW  - Tephrostratigraphy
KW  - Neogene
KW  - Cappadocia
KW  - Turkey
Y1  - 2014
U6  - https://doi.org/10.1016/j.chemer.2014.05.001
SN  - 0009-2819
SN  - 1611-5864
VL  - 74
IS  - 3
SP  - 471
EP  - 488
PB  - Elsevier
CY  - Jena
ER  - 
TY  - THES
A1  - Mayer, Michael
T1  - Pulsar wind nebulae at high energies
BT  - a diverse population and exceptional twins
BT  - eine vielfältige Population und außergewöhnliche Zwillinge
N2  - Pulsar wind nebulae (PWNe) are the most abundant TeV gamma-ray emitters in the Milky Way. The radiative emission of these objects is powered by fast-rotating pulsars, which donate parts of their rotational energy into winds of relativistic particles. This thesis presents an in-depth study of the detected population of PWNe at high energies. To outline general trends regarding their evolutionary behaviour, a time-dependent model is introduced and compared to the available data. In particular, this work presents two exceptional PWNe which protrude from the rest of the population, namely the Crab Nebula and N 157B. Both objects are driven by pulsars with extremely high rotational energy loss rates. Accordingly, they are often referred to as energetic twins. Modelling the non-thermal multi-wavelength emission of N157B gives access to specific properties of this object, like the magnetic field inside the nebula. Comparing the derived parameters to those of the Crab Nebula reveals large intrinsic differences between the two PWNe. Possible origins of these differences are discussed in context of the resembling pulsars.
Compared to the TeV gamma-ray regime, the number of detected PWNe is much smaller in the MeV-GeV gamma-ray range. In the latter range, the Crab Nebula stands out by the recent detection of gamma-ray flares. In general, the measured flux enhancements on short time scales of days to weeks were not expected in the theoretical understanding of PWNe. In this thesis, the variability of the Crab Nebula is analysed using data from the Fermi Large Area Telescope (Fermi-LAT). For the presented analysis, a new gamma-ray reconstruction method is used, providing a higher sensitivity and a lower energy threshold compared to previous analyses. The derived gamma-ray light curve of the Crab Nebula is investigated for flares and periodicity. The detected flares are analysed regarding their energy spectra, and their variety and commonalities are discussed. In addition, a dedicated analysis of the flare which occurred in March 2013 is performed. The derived short-term variability time scale is roughly 6h, implying a small region inside the Crab Nebula to be responsible for the enigmatic flares. The most promising theories explaining the origins of the flux eruptions and gamma-ray variability are discussed in detail.
In the technical part of this work, a new analysis framework is presented. The introduced software, called gammalib/ctools, is currently being developed for the future CTA observa- tory. The analysis framework is extensively tested using data from the H. E. S. S. experiment. To conduct proper data analysis in the likelihood framework of gammalib/ctools, a model describing the distribution of background events in H.E.S.S. data is presented. The software provides the infrastructure to combine data from several instruments in one analysis. To study the gamma-ray emitting PWN population, data from Fermi-LAT and H. E. S. S. are combined in the likelihood framework of gammalib/ctools. In particular, the spectral peak, which usually lies in the overlap energy regime between these two instruments, is determined with the presented analysis framework. The derived measurements are compared to the predictions from the time-dependent model. The combined analysis supports the conclusion of a diverse population of gamma-ray emitting PWNe.
N2  - Pulsarwindnebel (PWN) sind im Bereich der TeV Gammastrahlung die am häufigsten vorkommende Quellklasse. Die vorliegende Arbeit präsentiert eine detaillierte Studie der Population von gammastrahlungsemittierenden PWNn. Um ihre Entwicklung zu untersuchen, wird ein zeitabhängiges Modell vorgestellt und mit Messdaten verglichen. Der Fokus dieser Arbeit liegt des Weiteren auf zwei außergewöhnlichen PWNn, die aus der übrigen Population hervorstechen: der Krebsnebel und N 157B. Diese beiden PWN werden von Pulsaren mit ähnlich hohen Rotationsenergieverlustraten gespeist. Daher werden die beiden Pulsare auch oft als “energetische Zwillinge” bezeichnet.
Im Rahmen dieser Arbeit wird die Breitbandemission von N 157B modelliert. Dies ermöglicht es, spezielle Eigenschaften dieses PWNs abzuschätzen. Diese sind im Vergleich zum Krebsnebel sehr unterschiedlich, obwohl sich die jeweiligen Energiequellen stark ähneln. Es werden verschiedene Möglichkeiten für die unterschiedliche Erscheinung dieser beiden Quellen diskutiert.
Auf Grund kürzlich gemessener MeV Gammastrahlungsausbrüche wird die Einzigartigkeit des Krebsnebels in diesem Energiebereich verdeutlicht. Die auf Zeitskalen von Tagen bis Wochen variierende Helligkeit ist nach dem gegenwärtigen Verständnis von PWNn unerwartet. In dieser Arbeit wird die zeitliche Variabilität des Krebsnebels mit Daten vom Fermi Large Area Telescope (Fermi-LAT) analysiert. Die vorgestellte Datenanalyse basiert auf einer neuen Rekonstruktionsmethode von Gammastrahlen, welche zu einer höheren Empfindlichkeit und einer niedrigeren Energieschwelle führt. Die Lichtkurve des Krebsnebels in Gammastrahlung wird auf Periodizität und Variabilität untersucht. Des Weiteren werden die nachgewiesenen Strahlungsausbrüche hinsichtlich ihrer Energiespektren ausgewertet und miteinander auf Gemeinsamkeiten und Unterschiede verglichen. Zusätzlich wird eine detaillierte Analyse der starken Flusserhöhung vom März 2013 vorgestellt. Die hierbei bestimmte Kurzzeitvariabilität von ca. sechs Stunden lässt vermuten, dass eine sehr kleine Region innerhalb des Krebsnebels für die Strahlungsausbrüche verantwortlich ist. Die vielversprechendsten Theorien zu diesem Phänomen werden vorgestellt und diskutiert.
Im technischen Teil dieser Arbeit wird eine neue Analyseumgebung vorgestellt, die derzeit für das zukünftige CTA Observatorium entwickelt wird. Diese Software wird intensiven Analysetests mit Daten des H.E.S.S. Experiments unterzogen. Für die angemessene Durchführung von H.E.S.S. Datenanalysen wird ein Modell vorgestellt, das die Verteilung der Untergrundereignisse in H. E. S. S. Daten beschreibt. Des Weiteren erlaubt die Analyseumgebung die Kombination von Daten mehrerer Instrumente. Diese einzigartige Option wird genutzt, um die beschriebene PWN Population genauer zu studieren. Zu diesem Zweck werden Daten von Fermi-LAT und H. E. S. S. gemeinsam analysiert. Von besonderem Interesse ist hierbei das spektrale Maximum von PWN, welches meist im energetischen Überlappbereich der beiden Instrumente liegt. Die Ergebnisse der gemeinsamen Analyse werden mit dem zeitabhängigen Modell für PWN verglichen. Die daraus gewonnenen Resultate verdeutlichen unter anderem die breite Vielfalt von PWNn.
T2  - Pulsarwindnebel bei hohen Energien
KW  - Crab Nebula
KW  - N157B
KW  - gammalib/ctools
KW  - gamma-ray astronomy
KW  - data analysis
KW  - Gammastrahlungsastronomie
KW  - Fermi-LAT
KW  - H.E.S.S.
KW  - Statistische Datenanalyse
KW  - Krebsnebel
KW  - N157B
KW  - Pulsarwindnebel
Y1  - 2014
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-71504
ER  - 
TY  - JOUR
A1  - Mayer, Michael
T1  - Tarkovskijs Scham
JF  - Andrej Tarkovskij: Klassiker – Классик – Classic – Classico : Beiträge zum internationalen Tarkovskij-Symposium an der Universität Potsdam ; Band 2
Y1  - 2016
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-100458
SN  - 978-3-86956-352-7
SP  - 365
EP  - 376
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - CHAP
A1  - Кононенко, Наталия
A1  - Calabretto, Roberto
A1  - Mayer, Michael
A1  - Киршбаум, Генрих
A1  - Salvestroni, Simonetta
A1  - Zehnder, Christian
A1  - Булгакова, Oксана
A1  - Vassilieva, Ekaterina
A1  - Paperny, Vladimir
A1  - Engel, Christine
A1  - Christians, Heiko
A1  - Petzer, Tatjana
A1  - Pellanda, Marina
A1  - Вардиц, Владислава
ED  - Franz, Norbert P.
T1  - Andrej Tarkovskij: Klassiker – Классик – Classic – Classico
BT  - Beiträge zum internationalen Tarkovskij-Symposium an der Universität Potsdam ; Band 2
N2  - Vom 18. bis 20. September 2014 versammelten sich an der Universität Potsdam kultur- und filmwissenschaftlich arbeitende Wissenschaftler zu einem Andrej Tarkovskij gewidmeten Symposium, dem ersten internationalen. Die 25 Teilnehmer kamen nämlich aus neun Ländern. Dadurch, dass nicht wenige auch eine – wie man heute sagt – „Migrationsbiographie“ haben, potenzierte sich die durch die jeweils unterschiedliche Herkunft bedingte Multiperspektivik, zu der jedoch der Modus der Wissenschaftlichkeit ein deutlich relativierendes Korrektiv bildet. Der vorliegende Band enthält im Wesentlichen die dort vorgestellten Beiträge, aber auch die der Fachleute, die nicht persönlich hatten nach Potsdam kommen können.
Y1  - 2016
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-90975
SN  - 978-3-86956-352-7
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Risch, Lucie
A1  - Wochatz, Monique
A1  - Messerschmidt, Janin
A1  - Engel, Tilman
A1  - Mayer, Frank
A1  - Cassel, Michael
T1  - Reliability of evaluating achilles tendon vascularization assessed with doppler ultrasound advanced dynamic flow
JF  - Journal of ultrasound in medicine
N2  - The reliability of quantifying intratendinous vascularization by high-sensitivity Doppler ultrasound advanced dynamic flow has not been examined yet. Therefore, this study aimed to investigate the intraobserver and interobserver reliability of evaluating Achilles tendon vascularization by advanced dynamic flow using established scoring systems. Methods-Three investigators evaluated vascularization in 67 recordings in a test-retest design, applying the Ohberg score, a modified Ohberg score, and a counting score. Intraobserver and interobserver agreement for the Ohberg score and modified Ohberg score was analyzed by the Cohen kappa and Fleiss kappa coefficients (absolute), Kendall tau b coefficient, and Kendall coefficient of concordance (W; relative). The reliability of the counting score was analyzed by intraclass correlation coefficients (ICC) 2.1 and 3.1, the standard error of measurement (SEM), and Bland-Altman analysis (bias and limits of agreement [LoA]). Results-Intraobserver and interobserver agreement (absolute/relative) ranged from 0.61 to 0.87/0.87 to 0.95 and 0.11 to 0.66/0.76 to 0.89 for the Ohberg score and from 0.81 to 0.87/0.92 to 0.95 and 0.64 to 0.80/0.88 to 0.93 for the modified Ohberg score, respectively. The counting score revealed an intraobserver ICC of 0.94 to 0.97 (SEM, 1.0-1.5; bias, -1; and LoA, 3-4 vessels). The interobserver ICC for the counting score ranged from 0.91 to 0.98 (SEM, 1.0-1.9; bias, 0; and LoA, 3-5 vessels). Conclusions-The modified Ohberg score and counting score showed excellent reliability and seem convenient for research and clinical practice. The Ohberg score revealed decent intraobserver but unexpected low interobserver reliability and therefore cannot be recommended.
KW  - advanced dynamic flow
KW  - intratendinous blood flow
KW  - musculoskeletal
KW  - reliability
KW  - ultrasound
Y1  - 2017
U6  - https://doi.org/10.1002/jum.14414
SN  - 0278-4297
SN  - 1550-9613
VL  - 37
IS  - 3
SP  - 737
EP  - 744
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Müller, Steffen
A1  - Müller, Juliane
A1  - Stoll, Josefine
A1  - Prieske, Olaf
A1  - Cassel, Michael
A1  - Mayer, Frank
T1  - Incidence of back pain in adolescent athletes
BT  - a prospective study
JF  - BMC sports science, medicine & rehabilitation
N2  - Background

Recently, the incidence rate of back pain (BP) in adolescents has been reported at 21%. However, the development of BP in adolescent athletes is unclear. Hence, the purpose of this study was to examine the incidence of BP in young elite athletes in relation to gender and type of sport practiced.

Methods

Subjective BP was assessed in 321 elite adolescent athletes (m/f 57%/43%; 13.2 ± 1.4 years; 163.4 ± 11.4 cm; 52.6 ± 12.6 kg; 5.0 ± 2.6 training yrs; 7.6 ± 5.3 training h/week). Initially, all athletes were free of pain. The main outcome criterion was the incidence of back pain [%] analyzed in terms of pain development from the first measurement day (M1) to the second measurement day (M2) after 2.0 ± 1.0 year. Participants were classified into athletes who developed back pain (BPD) and athletes who did not develop back pain (nBPD). BP (acute or within the last 7 days) was assessed with a 5-step face scale (face 1–2 = no pain; face 3–5 = pain). BPD included all athletes who reported faces 1 and 2 at M1 and faces 3 to 5 at M2. nBPD were all athletes who reported face 1 or 2 at both M1 and M2. Data was analyzed descriptively. Additionally, a Chi2 test was used to analyze gender- and sport-specific differences (p = 0.05).

Results

Thirty-two athletes were categorized as BPD (10%). The gender difference was 5% (m/f: 12%/7%) but did not show statistical significance (p = 0.15). The incidence of BP ranged between 6 and 15% for the different sport categories. Game sports (15%) showed the highest, and explosive strength sports (6%) the lowest incidence. Anthropometrics or training characteristics did not significantly influence BPD (p = 0.14 gender to p = 0.90 sports; r2 = 0.0825).

Conclusions

BP incidence was lower in adolescent athletes compared to young non-athletes and even to the general adult population. Consequently, it can be concluded that high-performance sports do not lead to an additional increase in back pain incidence during early adolescence. Nevertheless, back pain prevention programs should be implemented into daily training routines for sport categories identified as showing high incidence rates.
KW  - Pain occurrence
KW  - Young athletes
KW  - Injury
KW  - Training volume
Y1  - 2016
U6  - https://doi.org/10.1186/s13102-016-0064-7
SN  - 2052-1847
VL  - 8
PB  - BioMed Central
CY  - London
ER  - 
TY  - CHAP
A1  - Kopinski, Stephan
A1  - Engel, Tilman
A1  - Cassel, Michael
A1  - Carlsohn, Anja
A1  - Mayer, Frank
T1  - Reliability of ultrasound measurements for subcutaneous adipose tissue in elite canoe athletes
T2  - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine
Y1  - 2014
SN  - 0195-9131
SN  - 1530-0315
VL  - 46
IS  - 5
SP  - 539
EP  - 539
PB  - Lippincott Williams & Wilkins
CY  - Philadelphia
ER  - 
TY  - GEN
A1  - Müller, Steffen
A1  - Stoll, Josefine
A1  - Cassel, Michael
A1  - Mayer, Frank
T1  - Trunk Muscle Activity during Drop Jump Performance in Adolescent Athletes with Back Pain
N2  - In the context of back pain, great emphasis has been placed on the importance of trunk stability, especially in situations requiring compensation of repetitive, intense loading induced during high-performance activities, e.g., jumping or landing. This study aims to evaluate trunk muscle activity during drop jump in adolescent athletes with back pain (BP) compared to athletes without back pain (NBP). Eleven adolescent athletes suffering back pain (BP: m/f: n = 4/7; 15.9 ± 1.3 y; 176 ± 11 cm; 68 ± 11 kg; 12.4 ± 10.5 h/we training) and 11 matched athletes without back pain (NBP: m/f: n = 4/7; 15.5 ± 1.3 y; 174 ± 7 cm; 67 ± 8 kg; 14.9 ± 9.5 h/we training) were evaluated. Subjects conducted 3 drop jumps onto a force plate (ground reaction force). Bilateral 12-lead SEMG (surface Electromyography) was applied to assess trunk muscle activity. Ground contact time [ms], maximum vertical jump force [N], jump time [ms] and the jump performance index [m/s] were calculated for drop jumps. SEMG amplitudes (RMS: root mean square [%]) for all 12 single muscles were normalized to MIVC (maximum isometric voluntary contraction) and analyzed in 4 time windows (100 ms pre- and 200 ms post-initial ground contact, 100 ms pre- and 200 ms post-landing) as outcome variables. In addition, muscles were grouped and analyzed in ventral and dorsal muscles, as well as straight and transverse trunk muscles. Drop jump ground reaction force variables did not differ between NBP and BP (p > 0.05). Mm obliquus externus and internus abdominis presented higher SEMG amplitudes (1.3–1.9-fold) for BP (p < 0.05). Mm rectus abdominis, erector spinae thoracic/lumbar and latissimus dorsi did not differ (p > 0.05). The muscle group analysis over the whole jumping cycle showed statistically significantly higher SEMG amplitudes for BP in the ventral (p = 0.031) and transverse muscles (p = 0.020) compared to NBP. Higher activity of transverse, but not straight, trunk muscles might indicate a specific compensation strategy to support trunk stability in athletes with back pain during drop jumps. Therefore, exercises favoring the transverse trunk muscles could be recommended for back pain treatment.
T3  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 319 
KW  - SEMG-pattern
KW  - back pain
KW  - drop jump
KW  - neuromuscular
KW  - performance
KW  - pre-activity
KW  - trunk
KW  - young athletes
Y1  - 2017
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-395261
ER  - 
TY  - GEN
A1  - Bisi-Balogun, Adebisi
A1  - Cassel, Michael
A1  - Mayer, Frank
T1  - Reliability of various measurement stations for determining plantar fascia thickness and echogenicity
N2  - This study aimed to determine the relative and absolute reliability of ultrasound (US) measurements of the thickness and echogenicity of the plantar fascia (PF) at different measurement stations along its length using a standardized protocol. Twelve healthy subjects (24 feet) were enrolled. The PF was imaged in the longitudinal plane. Subjects were assessed twice to evaluate the intra-rater reliability. A quantitative evaluation of the thickness and echogenicity of the plantar fascia was performed using Image J, a digital image analysis and viewer software. A sonography evaluation of the thickness and echogenicity of the PF showed a high relative reliability with an Intra class correlation coefficient of 0.88 at all measurement stations. However, the measurement stations for both the PF thickness and echogenicity which showed the highest intraclass correlation coefficient (ICCs) did not have the highest absolute reliability. Compared to other measurement stations, measuring the PF thickness at 3 cm distal and the echogenicity at a region of interest 1 cm to 2 cm distal from its insertion at the medial calcaneal tubercle showed the highest absolute reliability with the least systematic bias and random error. Also, the reliability was higher using a mean of three measurements compared to one measurement. To reduce discrepancies in the interpretation of the thickness and echogenicity measurements of the PF, the absolute reliability of the different measurement stations should be considered in clinical practice and research rather than the relative reliability with the ICC.
T3  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 339 
KW  - plantar fascia
KW  - reliability
KW  - sonography
KW  - musculoskeletal
Y1  - 2017
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-400615
ER  - 
TY  - GEN
A1  - Carlsohn, Anja
A1  - Scharhag-Rosenberger, Friederike
A1  - Cassel, Michael
A1  - Mayer, Frank
T1  - Resting Metabolic Rate in Elite Rowers and Canoeists: Difference between Indirect Calorimetry and Prediction
N2  - Background: Athletes may differ in their resting metabolic rate (RMR) from the general population. However, to estimate the RMR in athletes, prediction equations that have not been validated in athletes are often used. The purpose of this study was therefore to verify the applicability of commonly used RMR predictions for use in athletes. Methods: The RMR was measured by indirect calorimetry in 17 highly trained rowers and canoeists of the German national teams (BMI 24 ± 2 kg/m2, fat-free mass 69 ± 15 kg). In addition, the RMR was predicted using Cunningham (CUN) and Harris-Benedict (HB) equations. A two-way repeated measures ANOVA was calculated to test for differences between predicted and measured RMR (α = 0.05). The root mean square percentage error (RMSPE) was calculated and the Bland-Altman procedure was used to quantify the bias for each prediction. Results: Prediction equations significantly underestimated the RMR in males (p < 0.001). The RMSPE was calculated to be 18.4% (CUN) and 20.9% (HB) in the entire group. The bias was 133 kcal/24 h for CUN and 202 kcal/24 h for HB. Conclusions: Predictions significantly underestimate the RMR in male heavyweight endurance athletes but not in females. In athletes with a high fat-free mass, prediction equations might therefore not be applicable to estimate energy requirements. Instead, measurement of the resting energy expenditure or specific prediction equations might be needed for the individual heavyweight athlete.
T3  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 329 
KW  - Energy requirement
KW  - Calorimetry
KW  - Fat-free mass
KW  - Nutritional counseling
KW  - Athletes
Y1  - 2017
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-399837
ER  - 
TY  - GEN
A1  - Cassel, Michael
A1  - Intziegianni, Konstantina
A1  - Risch, Lucie
A1  - Müller, Steffen
A1  - Engel, Tilman
A1  - Mayer, Frank
T1  - Physiological Tendon Thickness Adaptation in Adolescent Elite Athletes
BT  - A Longitudinal Study
N2  - Increased Achilles (AT) and Patellar tendon (PT) thickness in adolescent athletes compared to non-athletes could be shown. However, it is unclear, if changes are of pathological or physiological origin due to training. The aim of this study was to determine physiological AT and PT thickness adaptation in adolescent elite athletes compared to non-athletes, considering sex and sport. In a longitudinal study design with two measurement days (M1/M2) within an interval of 3.2 ± 0.8 years, 131 healthy adolescent elite athletes (m/f: 90/41) out of 13 different sports and 24 recreationally active controls (m/f: 6/18) were included. Both ATs and PTs were measured at standardized reference points. Athletes were divided into 4 sport categories [ball (B), combat (C), endurance (E) and explosive strength sports (S)]. Descriptive analysis (mean ± SD) and statistical testing for group differences was performed (α = 0.05). AT thickness did not differ significantly between measurement days, neither in athletes (5.6 ± 0.7 mm/5.6 ± 0.7 mm) nor in controls (4.8 ± 0.4 mm/4.9 ± 0.5 mm, p > 0.05). For PTs, athletes presented increased thickness at M2 (M1: 3.5 ± 0.5 mm, M2: 3.8 ± 0.5 mm, p < 0.001). In general, males had thicker ATs and PTs than females (p < 0.05). Considering sex and sports, only male athletes from B, C, and S showed significant higher PT-thickness at M2 compared to controls (p ≤ 0.01). Sport-specific adaptation regarding tendon thickness in adolescent elite athletes can be detected in PTs among male athletes participating in certain sports with high repetitive jumping and strength components. Sonographic microstructural analysis might provide an enhanced insight into tendon material properties enabling the differentiation of sex and influence of different sports.
T3  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 355 
KW  - Achilles and patellar tendon
KW  - non-athletes
KW  - sonography
KW  - training adaptation
KW  - young athletes
Y1  - 2017
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-403823
ER  - 
TY  - GEN
A1  - Koch, Sarah
A1  - Cassel, Michael
A1  - Linne, Karsten
A1  - Mayer, Frank
A1  - Scharhag, Jürgen
T1  - ECG and echocardiographic findings in 10–15-year-old elite athletes
N2  - Background: Data on electrocardiographic and echocardiographic pre-participation screening findings in paediatric athletes are limited.

Methods and results: 10-15 year-old athletes (n = 343) were screened using electro- and echocardiography. The electrocardiogram (ECG) was normal in 220 (64%), mildly abnormal in 108 (31%), and distinctly abnormal in 15 (4%) athletes. Echocardiographic upper reference limits (URL, 97.5 percentile) for the left ventricular (LV) wall thickness in 10-11-year-old boys and girls were 9-10 mm and 8-9 mm, respectively; in 12-13-year-old boys and girls 9-10 mm; and in 14-15-year-old boys and girls 10-11 mm and 9-10 mm, respectively. Three athletes were excluded from competitive sports: one for symptomatic Wolff-Parkinson-White syndrome with a normal echocardiogram; one for negative T-waves in V-1-V-4 and a dilated right ventricle by echocardiography suggestive of (arrhythmogenic) right ventricular disease; and one for normal ECG and biscupid aortic valve including an aneurysm of the ascending aorta detected by echocardiography. Related to echocardiographic findings, the sensitivity and specificity of the ECG to identify cardiovascular abnormalities was 38% and 64%, respectively. The ECG's positive-predictive and negative-predictive values were 13% and 88%, respectively. The numbers needed to screen and calculated costs were 172 for ECG ( 7049), 172 for echocardiography ( 11,530), and 114 combining ECG and echocardiography ( 9323).

Conclusions: Compared to adults, paediatric athletes presented with fewer distinctly abnormal ECGs, and there was no gender difference in paediatric athletes' ECG-pattern distribution. A combination of ECG and echocardiography for pre-participation screening of paediatric athletes is superior to ECG alone but 30% more costly.
T3  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 368 
KW  - ECG
KW  - echocardiography
KW  - paediatric athlete
KW  - pre-participation screening
KW  - sudden cardiac death
Y1  - 2017
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-403186
ER  - 
TY  - CHAP
A1  - Wippert, Pia-Maria
A1  - De Witt Huberts, Jessie
A1  - Honold, Jasmin
A1  - Holzmann, Caroline
A1  - Rector, Michael V.
A1  - Mayer, Frank
T1  - Chronic stress measurement methods and their comparability
T2  - Psychosomatic medicine
Y1  - 2014
SN  - 0033-3174
SN  - 1534-7796
VL  - 76
IS  - 3
SP  - A129
EP  - A129
PB  - Lippincott Williams & Wilkins
CY  - Philadelphia
ER  - 
TY  - JOUR
A1  - Müller, Steffen
A1  - Stoll, Josefine
A1  - Mueller, Juliane
A1  - Cassel, Michael
A1  - Mayer, Frank
T1  - Trunk Muscle Activity during Drop Jump Performance in Adolescent Athletes with Back Pain
JF  - Frontiers in physiology
N2  - In the context of back pain, great emphasis has been placed on the importance of trunk stability, especially in situations requiring compensation of repetitive, intense loading induced during high-performance activities, e.g., jumping or landing. This study aims to evaluate trunk muscle activity during drop jump in adolescent athletes with back pain (BP) compared to athletes without back pain (NBP). Eleven adolescent athletes suffering back pain (BP: m/f: n = 4/7; 15.9 +/- 1.3 y; 176 +/- 11 cm; 68 +/- 11 kg; 12.4 +/- 10.5 h/we training) and 11 matched athletes without back pain (NBP: m/f: n = 4/7; 15.5 +/- 1.3 y; 174 +/- 7 cm; 67 +/- 8 kg; 14.9 +/- 9.5 h/we training) were evaluated. Subjects conducted 3 drop jumps onto a force plate (ground reaction force). Bilateral 12-lead SEMG (surface Electromyography) was applied to assess trunk muscle activity. Ground contact time [ms], maximum vertical jump force [N], jump time [ms] and the jump performance index [m/s] were calculated for drop jumps. SEMG amplitudes (RMS: root mean square [%]) for all 12 single muscles were normalized toMIVC (maximum isometric voluntary contraction) and analyzed in 4 time windows (100 ms pre- and 200 ms post-initial ground contact, 100 ms pre- and 200 ms post-landing) as outcome variables. In addition, muscles were grouped and analyzed in ventral and dorsal muscles, as well as straight and transverse trunk muscles. Drop jump ground reaction force variables did not differ between NBP and BP (p > 0.05). Mm obliquus externus and internus abdominis presented higher SEMG amplitudes (1.3-1.9-fold) for BP (p < 0.05). Mm rectus abdominis, erector spinae thoracic/lumbar and latissimus dorsi did not differ (p > 0.05). The muscle group analysis over the whole jumping cycle showed statistically significantly higher SEMG amplitudes for BP in the ventral (p = 0.031) and transverse muscles (p = 0.020) compared to NBP. Higher activity of transverse, but not straight, trunk muscles might indicate a specific compensation strategy to support trunk stability in athletes with back pain during drop jumps. Therefore, exercises favoring the transverse trunk muscles could be recommended for back pain treatment.
KW  - SEMG-pattern
KW  - back pain
KW  - pre-activity
KW  - drop jump
KW  - neuromuscular
KW  - trunk
KW  - performance
KW  - young athletes
Y1  - 2017
U6  - https://doi.org/10.3389/fphys.2017.00274
SN  - 1664-042X
VL  - 8
SP  - 124
EP  - 132
PB  - Frontiers Research Foundation
CY  - Lausanne
ER  - 
TY  - CHAP
A1  - Cassel, Michael
A1  - Carlsohn, Anja
A1  - Froehlich, Katja
A1  - Mayer, Frank
T1  - Achilles tendinopathy in adolescent athletes using ultrasound and clinical examination
T2  - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine
Y1  - 2013
SN  - 0195-9131
SN  - 1530-0315
VL  - 45
IS  - 5
SP  - 350
EP  - 350
PB  - Lippincott Williams & Wilkins
CY  - Philadelphia
ER  - 
TY  - GEN
A1  - Eichler, Sarah
A1  - Salzwedel, Annett
A1  - Rabe, Sophie
A1  - Mueller, Steffen
A1  - Mayer, Frank
A1  - Wochatz, Monique
A1  - Hadzic, Miralem
A1  - John, Michael
A1  - Wegscheider, Karl
A1  - Völler, Heinz
T1  - The Effectiveness of Telerehabilitation as a Supplement to Rehabilitation in Patients After Total Knee or Hip Replacement
BT  - Randomized Controlled Trial
T2  - Postprints der Universität Potsdam : Humanwissenschaftliche Reihe
N2  - Background: Telerehabilitation can contribute to the maintenance of successful rehabilitation regardless of location and time. The aim of this study was to investigate a specific three-month interactive telerehabilitation routine regarding its effectiveness in assisting patients with physical functionality and with returning to work compared to typical aftercare.

Objective: The aim of the study was to investigate a specific three-month interactive telerehabilitation with regard to effectiveness in functioning and return to work compared to usual aftercare.

Methods: From August 2016 to December 2017, 111 patients (mean 54.9 years old; SD 6.8; 54.3% female) with hip or knee replacement were enrolled in the randomized controlled trial. At discharge from inpatient rehabilitation and after three months, their distance in the 6-minute walk test was assessed as the primary endpoint. Other functional parameters, including health related quality of life, pain, and time to return to work, were secondary endpoints.

Results: Patients in the intervention group performed telerehabilitation for an average of 55.0 minutes (SD 9.2) per week. Adherence was high, at over 75%, until the 7th week of the three-month intervention phase. Almost all the patients and therapists used the communication options. Both the intervention group (average difference 88.3 m; SD 57.7; P=.95) and the control group (average difference 79.6 m; SD 48.7; P=.95) increased their distance in the 6-minute-walk-test. Improvements in other functional parameters, as well as in quality of life and pain, were achieved in both groups. The higher proportion of working patients in the intervention group (64.6%; P=.01) versus the control group (46.2%) is of note.

Conclusions: The effect of the investigated telerehabilitation therapy in patients following knee or hip replacement was equivalent to the usual aftercare in terms of functional testing, quality of life, and pain. Since a significantly higher return-to-work rate could be achieved, this therapy might be a promising supplement to established aftercare.
T3  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 589 
KW  - telerehabilitation
KW  - home-based
KW  - total hip replacement
KW  - total knee replacement
KW  - exercise therapy
KW  - aftercare
KW  - rehabilitation
Y1  - 2019
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-440965
SN  - 1866-8364
IS  - 589
ER  - 
TY  - GEN
A1  - Cassel, Michael
A1  - Müller, Juliane
A1  - Moser, Othmar
A1  - Strempler, Mares Elaine
A1  - Reso, Judith
A1  - Mayer, Frank
T1  - Orthopedic Injury Profiles in Adolescent Elite Athletes
BT  - A Retrospective Analysis From a Sports Medicine Department
T2  - Postprints der Universität Potsdam Humanwissenschaftliche Reihe
N2  - Aim: The aim of the study was to identify common orthopedic sports injury profiles in adolescent elite athletes with respect to age, sex, and anthropometrics.

Methods: A retrospective data analysis of 718 orthopedic presentations among 381 adolescent elite athletes from 16 different sports to a sports medical department was performed. Recorded data of history and clinical examination included area, cause and structure of acute and overuse injuries. Injury-events were analyzed in the whole cohort and stratified by age (11–14/15–17 years) and sex. Group differences were tested by chi-squared-tests. Logistic regression analysis was applied examining the influence of factors age, sex, and body mass index (BMI) on the outcome variables area and structure (a = 0.05).

Results: Higher proportions of injury-events were reported for females (60%) and athletes of the older age group (66%) than males and younger athletes. The most frequently injured area was the lower extremity (47%) followed by the spine (30.5%) and the upper extremity (12.5%). Acute injuries were mainly located at the lower extremity (74.5%), while overuse injuries were predominantly observed at the lower extremity (41%) as well as the spine (36.5%). Joints (34%), muscles (22%), and tendons (21.5%) were found to be the most often affected structures. The injured structures were different between the age groups (p = 0.022), with the older age group presenting three times more frequent with ligament pathology events (5.5%/2%) and less frequent with bony problems (11%/20.5%) than athletes of the younger age group. The injured area differed between the sexes (p = 0.005), with males having fewer spine injury-events (25.5%/34%) but more upper extremity injuries (18%/9%) than females. Regression analysis showed statistically significant influence for BMI (p = 0.002) and age (p = 0.015) on structure, whereas the area was significantly influenced by sex (p = 0.005).

Conclusion: Events of soft-tissue overuse injuries are the most common reasons resulting in orthopedic presentations of adolescent elite athletes. Mostly, the lower extremity and the spine are affected, while sex and age characteristics on affected area and structure must be considered. Therefore, prevention strategies addressing the injury-event profiles should already be implemented in early adolescence taking age, sex as well as injury entity into account.
T3  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 559 
KW  - overuse injuries
KW  - epidemiology
KW  - complaints
KW  - symptoms
KW  - risk factors
KW  - sports
Y1  - 2019
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-434953
SN  - 1866-8364
IS  - 559
ER  - 
TY  - JOUR
A1  - Cassel, Michael
A1  - Intziegianni, Konstantina
A1  - Risch, Lucie
A1  - Mueller, Steffen
A1  - Engel, Tilman
A1  - Mayer, Frank
T1  - Physiological Tendon Thickness Adaptation in Adolescent Elite Athletes: A Longitudinal Study
JF  - Frontiers in physiology
N2  - Increased Achilles (AT) and Patellar tendon (PT) thickness in adolescent athletes compared to non-athletes could be shown. However, it is unclear, if changes are of pathological or physiological origin due to training. The aim of this study was to determine physiological AT and PT thickness adaptation in adolescent elite athletes compared to non-athletes, considering sex and sport. In a longitudinal study design with two measurement days (M1/M2) within an interval of 3.2 +/- 0.8 years, 131 healthy adolescent elite athletes (m/f: 90/41) out of 13 different sports and 24 recreationally active controls (m/f: 6/18) were included. Both ATs and PTs were measured at standardized reference points. Athletes were divided into 4 sport categories [ball (B), combat (C), endurance (E) and explosive strength sports (S)]. Descriptive analysis (mean SD) and statistical testing for group differences was performed (cy = 0.05). AT thickness did not differ significantly between measurement days, neither in athletes (5.6 +/- 0.7 mm/5.6 +/- 0.7 mm) nor in controls (4.8 +/- 0.4 mm/4.9 +/- 0.5 mm, p > 0.05). For PTs, athletes presented increased thickness at M2 (Ml: 3.5 +/- 0.5 mm, M2: 3.8 +/- 0.5 mm, p < 0.001). In general, males had thicker ATs and PTs than females (p < 0.05). Considering sex and sports, only male athletes from B, C, and S showed significant higher PT-thickness at M2 compared to controls (p <= 0.01). Sport-specific adaptation regarding tendon thickness in adolescent elite athletes can be detected in PTs among male athletes participating in certain sports with high repetitive jumping and strength components. Sonographic microstructural analysis might provide an enhanced insight into tendon material properties enabling the differentiation of sex and influence of different sports.
KW  - Achilles and patellar tendon
KW  - training adaptation
KW  - sonography
KW  - young athletes
KW  - non-athletes
Y1  - 2017
U6  - https://doi.org/10.3389/fphys.2017.00795
SN  - 1664-042X
VL  - 8
SP  - 599
EP  - 611
PB  - Frontiers Research Foundation
CY  - Lausanne
ER  - 
TY  - GEN
A1  - Risch, Lucie
A1  - Mayer, Frank
A1  - Cassel, Michael
T1  - Doppler flow response following running exercise differs between healthy and tendinopathic Achilles tendons
T2  - Postprints der Universität Potsdam : Humanwissenschaftliche Reihe
N2  - Background: The relationship between exercise-induced intratendinous blood flow (IBF) and tendon pathology or training exposure is unclear.

Objective: This study investigates the acute effect of running exercise on sonographic detectable IBF in healthy and tendinopathic Achilles tendons (ATs) of runners and recreational participants.

Methods: 48 participants (43 ± 13 years, 176 ± 9 cm, 75 ± 11 kg) performed a standardized submaximal 30-min constant load treadmill run with Doppler ultrasound “Advanced dynamic flow” examinations before (Upre) and 5, 30, 60, and 120 min (U5-U120) afterward. Included were runners (>30 km/week) and recreational participants (<10 km/week) with healthy (Hrun, n = 10; Hrec, n = 15) or tendinopathic (Trun, n = 13; Trec, n = 10) ATs. IBF was assessed by counting number [n] of intratendinous vessels. IBF data are presented descriptively (%, median [minimum to maximum range] for baseline-IBF and IBF-difference post-exercise). Statistical differences for group and time point IBF and IBF changes were analyzed with Friedman and Kruskal-Wallis ANOVA (α = 0.05).

Results: At baseline, IBF was detected in 40% (3 [1–6]) of Hrun, in 53% (4 [1–5]) of Hrec, in 85% (3 [1–25]) of Trun, and 70% (10 [2–30]) of Trec. At U5 IBF responded to exercise in 30% (3 [−1–9]) of Hrun, in 53% (4 [−2–6]) of Hrec, in 70% (4 [−10–10]) of Trun, and in 80% (5 [1–10]) of Trec. While IBF in 80% of healthy responding ATs returned to baseline at U30, IBF remained elevated until U120 in 60% of tendinopathic ATs. Within groups, IBF changes from Upre-U120 were significant for Hrec (p < 0.01), Trun (p = 0.05), and Trec (p < 0.01). Between groups, IBF changes in consecutive examinations were not significantly different (p > 0.05) but IBF-level was significantly higher at all measurement time points in tendinopathic versus healthy ATs (p < 0.05).

Conclusion: Irrespective of training status and tendon pathology, running leads to an immediate increase of IBF in responding tendons. This increase occurs shortly in healthy and prolonged in tendinopathic ATs. Training exposure does not alter IBF occurrence, but IBF level is elevated in tendon pathology. While an immediate exercise-induced IBF increase is a physiological response, prolonged IBF is considered a pathological finding associated with Achilles tendinopathy.
T3  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 715 
KW  - neovascularization
KW  - tendinopathy
KW  - Doppler ultrasound
KW  - Advanced Dynamic Flow
KW  - athlete
KW  - sonography
Y1  - 2021
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-521367
SN  - 1866-8364
ER  - 
TY  - GEN
A1  - Müller, Steffen
A1  - Müller, Juliane
A1  - Stoll, Josefine
A1  - Prieske, Olaf
A1  - Cassel, Michael
A1  - Mayer, Frank
T1  - Incidence of back pain in adolescent athletes
BT  - a prospective study
N2  - Background

Recently, the incidence rate of back pain (BP) in adolescents has been reported at 21%. However, the development of BP in adolescent athletes is unclear. Hence, the purpose of this study was to examine the incidence of BP in young elite athletes in relation to gender and type of sport practiced.

Methods

Subjective BP was assessed in 321 elite adolescent athletes (m/f 57%/43%; 13.2 ± 1.4 years; 163.4 ± 11.4 cm; 52.6 ± 12.6 kg; 5.0 ± 2.6 training yrs; 7.6 ± 5.3 training h/week). Initially, all athletes were free of pain. The main outcome criterion was the incidence of back pain [%] analyzed in terms of pain development from the first measurement day (M1) to the second measurement day (M2) after 2.0 ± 1.0 year. Participants were classified into athletes who developed back pain (BPD) and athletes who did not develop back pain (nBPD). BP (acute or within the last 7 days) was assessed with a 5-step face scale (face 1–2 = no pain; face 3–5 = pain). BPD included all athletes who reported faces 1 and 2 at M1 and faces 3 to 5 at M2. nBPD were all athletes who reported face 1 or 2 at both M1 and M2. Data was analyzed descriptively. Additionally, a Chi2 test was used to analyze gender- and sport-specific differences (p = 0.05).

Results

Thirty-two athletes were categorized as BPD (10%). The gender difference was 5% (m/f: 12%/7%) but did not show statistical significance (p = 0.15). The incidence of BP ranged between 6 and 15% for the different sport categories. Game sports (15%) showed the highest, and explosive strength sports (6%) the lowest incidence. Anthropometrics or training characteristics did not significantly influence BPD (p = 0.14 gender to p = 0.90 sports; r2 = 0.0825).

Conclusions

BP incidence was lower in adolescent athletes compared to young non-athletes and even to the general adult population. Consequently, it can be concluded that high-performance sports do not lead to an additional increase in back pain incidence during early adolescence. Nevertheless, back pain prevention programs should be implemented into daily training routines for sport categories identified as showing high incidence rates.
T3  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 310 
KW  - Injury
KW  - Pain occurrence
KW  - Training volume
KW  - Young athletes
Y1  - 2017
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-101874
ER  - 
TY  - JOUR
A1  - Scharhag-Rosenberger, Friederike
A1  - Carlsohn, Anja
A1  - Cassel, Michael
A1  - Mayer, Frank
A1  - Scharhag, Jürgen
T1  - How to test maximal oxygen uptake a study on timing and testing procedure of a supramaximal verification test
JF  - Applied physiology, nutrition, and metabolism = Physiologie appliquée, nutrition et métabolisme
N2  - On utilise de plus en plus les tests de verification pour confirmer l'atteinte du consommation d'oxygene maximale (VO(2 max)). Toutefois, le moment et les methodes d'evaluation varient d'un groupe de travail a l'autre. Les objectifs de cette etude sont de constater si on peut administrer un test de verification apres un test d'effort progressif ou s'il est preferable de le faire une autre journee et si on peut determiner le VO(2 max) tout de meme lors de la premiere seance chez des sujets ne repondant pas au critere de verification. Quarante sujets (age, 24 +/- 4 ans; VO(2 max), 50 +/- 7 mL center dot min(-1)center dot kg(-1)) participent a un test d'effort progressif sur tapis roulant et, 10 min plus tard, a un test de verification (VerifDay1) a 110 % de la velocite maximale (v(max)). Le critere de verification est un VO(2) de pointe au VerifDay1 < 5,5 % a la valeur retenue au test d'effort progressif. Les sujets ne repondant pas au critere de verification passent un autre test de verification, mais a 115 % du VerifDay1', et ce, 10 min plus tard pour confirmer le VO(2) de pointe du VerifDay1 en tant que VO(2 max). Tous les autres sujets repassent le VerifDay1 a un jour different (VerifDay2). Six sujets sur quarante ne repondent pas au critere de verification. Chez quatre d'entre eux, on confirme l'atteinte du VO(2 max) au VerifDay1'. Le VO(2) de pointe au VerifDay1 est equivalent a celui du VerifDay2 (3722 +/- 991 mL center dot min(-1) comparativement a 3752 +/- 995 mL center dot min(-1), p = 0,56), mais le temps jusqu'a l'epuisement est significativement plus long au VerifDay2 (2:06 +/- 0:22 min:s comparativement a 2:42 +/- 0:38 min:s, p < 0,001, n = 34). Le VO(2) de pointe obtenu au test de verification ne semble pas conditionne par un test d'effort progressif maximal prealable. On peut donc realiser le test d'effort progressif et le test de verification lors de la meme seance d'evaluation. Chez presque tous les individus ne repondant pas au critere de verification, on peut determiner le VO(2 max) au moyen d'un autre test de verification plus intense.
Y1  - 2011
U6  - https://doi.org/10.1139/H10-099
SN  - 1715-5312
VL  - 36
IS  - 1
SP  - 153
EP  - 160
PB  - NRC Research Press
CY  - Ottawa
ER  - 
TY  - JOUR
A1  - Dolch, D.
A1  - Batsaikhan, Nyamsuren
A1  - Thiele, K.
A1  - Burger, F.
A1  - Scheffler, Ingo
A1  - Kiefer, A.
A1  - Mayer, Frank
A1  - Samjaa, R.
A1  - Stubbe, Annegret
A1  - Stubbe, Michael
A1  - Krall, L.
A1  - Steinhauser, D.
T1  - Contributions to the chiroptera of Mongolia with first evidences on species communities and ecological niches
Y1  - 2007
SN  - 0440-1298
ER  - 
TY  - GEN
A1  - Eichler, Sarah
A1  - Rabe, Sophie
A1  - Salzwedel, Annett
A1  - Müller, Steffen
A1  - Stoll, Josefine
A1  - Tilgner, Nina
A1  - John, Michael
A1  - Wegschneider, Karl
A1  - Mayer, Frank
A1  - Völler, Heinz
T1  - Effectiveness of an interactive telerehabilitation system with home-based exercise training in patients after total hip or knee replacement
BT  - Study protocol for a multicenter, superiority, no-blinded randomized controlled trial
N2  - Background

Total hip or knee replacement is one of the most frequently performed surgical procedures. Physical rehabilitation following total hip or knee replacement is an essential part of the therapy to improve functional outcomes and quality of life. After discharge from inpatient rehabilitation, a subsequent postoperative exercise therapy is needed to maintain functional mobility. Telerehabilitation may be a potential innovative treatment approach. We aim to investigate the superiority of an interactive telerehabilitation intervention for patients after total hip or knee replacement, in comparison to usual care, regarding physical performance, functional mobility, quality of life and pain.

Methods/design

This is an open, randomized controlled, multicenter superiority study with two prospective arms. One hundred and ten eligible and consenting participants with total knee or hip replacement will be recruited at admission to subsequent inpatient rehabilitation. After comprehensive, 3-week, inpatient rehabilitation, the intervention group performs a 3-month, interactive, home-based exercise training with a telerehabilitation system. For this purpose, the physiotherapist creates an individual training plan out of 38 different strength and balance exercises which were implemented in the system. Data about the quality and frequency of training are transmitted to the physiotherapist for further adjustment. Communication between patient and physiotherapist is possible with the system. The control group receives voluntary, usual aftercare programs. Baseline assessments are investigated after discharge from rehabilitation; final assessments 3 months later. The primary outcome is the difference in improvement between intervention and control group in 6-minute walk distance after 3 months. Secondary outcomes include differences in the Timed Up and Go Test, the Five-Times-Sit-to-Stand Test, the Stair Ascend Test, the Short-Form 36, the Western Ontario and McMaster Universities Osteoarthritis Index, the International Physical Activity Questionnaire, and postural control as well as gait and kinematic parameters of the lower limbs. Baseline-adjusted analysis of covariance models will be used to test for group differences in the primary and secondary endpoints.

Discussion

We expect the intervention group to benefit from the interactive, home-based exercise training in many respects represented by the study endpoints. If successful, this approach could be used to enhance the access to aftercare programs, especially in structurally weak areas.
T3  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 353 
KW  - Aftercare
KW  - Exercise therapy
KW  - Home-based
KW  - Telerehabilitation
KW  - Total hip replacement
KW  - Total knee replacement
Y1  - 2017
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-403702
ER  - 
TY  - JOUR
A1  - Eichler, Sarah
A1  - Salzwedel, Annett
A1  - Rabe, Sophie
A1  - Mueller, Steffen
A1  - Mayer, Frank
A1  - Wochatz, Monique
A1  - Hadzic, Miralem
A1  - John, Michael
A1  - Wegscheider, Karl
A1  - Völler, Heinz
T1  - The Effectiveness of Telerehabilitation as a Supplement to Rehabilitation in Patients After Total Knee or Hip Replacement
BT  - Randomized Controlled Trial
JF  - JMIR Rehabilitation and Assistive Technologies
N2  - Background: Telerehabilitation can contribute to the maintenance of successful rehabilitation regardless of location and time. The aim of this study was to investigate a specific three-month interactive telerehabilitation routine regarding its effectiveness in assisting patients with physical functionality and with returning to work compared to typical aftercare.

Objective: The aim of the study was to investigate a specific three-month interactive telerehabilitation with regard to effectiveness in functioning and return to work compared to usual aftercare.

Methods: From August 2016 to December 2017, 111 patients (mean 54.9 years old; SD 6.8; 54.3% female) with hip or knee replacement were enrolled in the randomized controlled trial. At discharge from inpatient rehabilitation and after three months, their distance in the 6-minute walk test was assessed as the primary endpoint. Other functional parameters, including health related quality of life, pain, and time to return to work, were secondary endpoints.

Results: Patients in the intervention group performed telerehabilitation for an average of 55.0 minutes (SD 9.2) per week. Adherence was high, at over 75%, until the 7th week of the three-month intervention phase. Almost all the patients and therapists used the communication options. Both the intervention group (average difference 88.3 m; SD 57.7; P=.95) and the control group (average difference 79.6 m; SD 48.7; P=.95) increased their distance in the 6-minute-walk-test. Improvements in other functional parameters, as well as in quality of life and pain, were achieved in both groups. The higher proportion of working patients in the intervention group (64.6%; P=.01) versus the control group (46.2%) is of note.

Conclusions: The effect of the investigated telerehabilitation therapy in patients following knee or hip replacement was equivalent to the usual aftercare in terms of functional testing, quality of life, and pain. Since a significantly higher return-to-work rate could be achieved, this therapy might be a promising supplement to established aftercare.
KW  - telerehabilitation
KW  - home-based
KW  - total hip replacement
KW  - total knee replacement
KW  - exercise therapy
KW  - aftercare
KW  - rehabilitation
Y1  - 2019
U6  - https://doi.org/10.2196/14236
SN  - 2369-2529
VL  - 6
IS  - 2
PB  - jmir rehab
CY  - Toronto
ER  - 
TY  - JOUR
A1  - König, Niklas
A1  - Cassel, Michael
A1  - Intziegianni, Konstantina
A1  - Mayer, Frank
T1  - Inter-rater reliability and measurement error of sonographic muscle architecture assessments
JF  - Journal of ultrasound in medicine
N2  - Objectives-Sonography of muscle architecture provides physicians and researchers with information about muscle function and muscle-related disorders. Inter-rater reliability is a crucial parameter in daily clinical routines. The aim of this study was to assess the inter-rater reliability of sonographic muscle architecture assessments and quantification of errors that arise from inconsistent probe positioning and image interpretation.
 Results-Inter-rater reliability was good overall (ICC, 0.77-0.90; IRV, 9.0%-13.4%; bias LoA, 0.2 +/- 0.2-1.7 +/- 3.0). Superior and inferior pennation angles showed high systematic bias and LoA in all setups, ranging from 2.0 degrees +/- 2.2 degrees to 3.4 degrees +/- 4.1 degrees. The highest IRV was found for muscle thickness (13.4%). "When the probe position was standardized, the SEM for muscle thickness decreased from 0.1 to 0.05 cm.
 Conclusions-Sonographic examination of muscle architecture of the medial gastrocnemius has good to high reliability. In contrast to pennation angle measurements, length measurements can be improved by standardization of the probe position.
KW  - gastrocnemius muscle
KW  - inter-rater variability
KW  - muscle architecture
KW  - musculoskeletal ultrasound
KW  - sonography
Y1  - 2014
U6  - https://doi.org/10.7863/ultra.33.5.769
SN  - 0278-4297
SN  - 1550-9613
VL  - 33
IS  - 5
SP  - 769
EP  - 777
PB  - American Institute of Ultrasound in Medicine
CY  - Laurel
ER  - 
TY  - GEN
A1  - Carlsohn, Anja
A1  - Cassel, Michael
A1  - Linné, Karsten
A1  - Mayer, Frank
T1  - How much is too much?
BT  - a case report of nutritional supplement use of a high-performance athlete
T2  - Postprints der Universität Potsdam : Humanwissenschaftliche Reihe
N2  - Although dietary nutrient intake is often adequate, nutritional supplement use is common among elite athletes. However, high-dose supplements or the use of multiple supplements may exceed the recommended daily allowance (RDA) of particular nutrients or even result in a daily intake above tolerable upper limits (UL). The present case report presents nutritional intake data and supplement use of a highly trained male swimmer competing at international level. Habitual energy and micronutrient intake were analysed by 3 d dietary reports. Supplement use and dosage were assessed, and total amount of nutrient supply was calculated. Micronutrient intake was evaluated based on RDA and UL as presented by the European Scientific Committee on Food, and maximum permitted levels in supplements (MPL) are given. The athlete’s diet provided adequate micronutrient content well above RDA except for vitamin D. Simultaneous use of ten different supplements was reported, resulting in excess intake above tolerable UL for folate, vitamin E and Zn. Additionally, daily supplement dosage was considerably above MPL for nine micronutrients consumed as artificial products. Risks and possible side effects of exceeding UL by the athlete are discussed. Athletes with high energy intake may be at risk of exceeding UL of particular nutrients if multiple supplements are added. Therefore, dietary counselling of athletes should include assessment of habitual diet and nutritional supplement intake. Educating athletes to balance their diets instead of taking supplements might be prudent to prevent health risks
that may occur with long-term excess nutrient intake.
T3  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 515 
KW  - dietary supplements
KW  - tolerable upper limits
KW  - elite athletes
KW  - vitamins
KW  - minerals
Y1  - 2019
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-412910
SN  - 1866-8364
IS  - 515
ER  - 
TY  - GEN
A1  - Risch, Lucie
A1  - Stoll, Josefine
A1  - Schomöller, Anne
A1  - Engel, Tilman
A1  - Mayer, Frank
A1  - Cassel, Michael
T1  - Intraindividual Doppler Flow Response to Exercise Differs Between Symptomatic and Asymptomatic Achilles Tendons
T2  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe
N2  - Objective: This study investigated intraindividual differences of intratendinous blood flow (IBF) in response to running exercise in participants with Achilles tendinopathy.

Design: This is a cross-sectional study.

Setting: The study was conducted at the University Outpatient Clinic.

Participants: Sonographic detectable intratendinous blood flow was examined in symptomatic and contralateral asymptomatic Achilles tendons of 19 participants (42 ± 13 years, 178 ± 10 cm, 76 ± 12 kg, VISA-A 75 ± 16) with clinically diagnosed unilateral Achilles tendinopathy and sonographic evident tendinosis.

Intervention: IBF was assessed using Doppler ultrasound “Advanced Dynamic Flow” before (Upre) and 5, 30, 60, and 120 min (U5–U120) after a standardized submaximal constant load run.

Main Outcome Measure: IBF was quantified by counting the number (n) of vessels in each tendon.

Results: At Upre, IBF was higher in symptomatic compared with asymptomatic tendons [mean 6.3 (95% CI: 2.8–9.9) and 1.7 (0.4–2.9), p < 0.01]. Overall, 63% of symptomatic and 47% of asymptomatic Achilles tendons responded to exercise, whereas 16 and 11% showed persisting IBF and 21 and 42% remained avascular throughout the investigation. At U5, IBF increased in both symptomatic and asymptomatic tendons [difference to baseline: 2.4 (0.3–4.5) and 0.9 (0.5–1.4), p = 0.05]. At U30 to U120, IBF was still increased in symptomatic but not in asymptomatic tendons [mean difference to baseline: 1.9 (0.8–2.9) and 0.1 (-0.9 to 1.2), p < 0.01].

Conclusion: Irrespective of pathology, 47–63% of Achilles tendons responded to exercise with an immediate acute physiological IBF increase by an average of one to two vessels (“responders”). A higher amount of baseline IBF (approximately five vessels) and a prolonged exercise-induced IBF response found in symptomatic ATs indicate a pain-associated altered intratendinous “neovascularization.”
T3  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 746 
KW  - achilles tendinopathy
KW  - tendinosis
KW  - neovascularization
KW  - ultrasound
KW  - advanced dynamic flow
KW  - sonography
Y1  - 2022
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-542865
SN  - 1866-8364
SP  - 1
EP  - 8
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Baur, Heiner
A1  - Hirschmüller, Anja
A1  - Cassel, Michael
A1  - Müller, Steffen
A1  - Mayer, Frank
T1  - Gender-specific neuromuscular activity of the M. peroneus longus in healthy runners : a descriptive laboratory study
N2  - Background: Gender-specific neuromuscular activity for the ankle (e.g., peroneal muscle) is currently not known. This knowledge may contribute to the understanding of overuse injury mechanisms. The purpose was therefore to analyse the neuromuscular activity of the peroneal muscle in healthy runners. Methods: Fifty-three male and 54 female competitive runners were tested on a treadmill at 3.33 m s(-1). Neuromuscular activity of the M. peroneus longus was measured by electromyography and analysed in the time domain (onset of activation, time of maximum of activation, total time of activation) in % of stride time in relation to touchdown (= 1.0). Additionally, mean amplitudes for the gait cycle phases preactivation, weight acceptance and push-off were calculated and normalised to the mean activity of the entire gait cycle. Findings: Onset of activation (mean; female: 0.86/male: 0.90, p<0.0001) and time of maximum of activation (female: 1.13/male: 1.16, p<0.0001) occurred earlier in female compared to male and the total time of activation was longer in women (female: 0.42/male: 0.39, p=0.0036). In preactivation, women showed higher amplitudes (+ 21%) compared to men (female: 1.16/male: 0.92, p<0.0001). Activity during weight acceptance (female: 2.26/male: 2.41, p = 0.0039) and push-off (female: 0.93/male: 1.07, p = 0.0027) were higher in men. Interpretation: Activation strategies of the peroneal muscle appear to be gender-specific. Higher preactivation amplitudes in females indicate a different neuromuscular control in anticipation of touchdown ("pre-programmed activity"). These data may help interpret epidemiologically reported differences between genders in overuse injury frequency and localisation.
Y1  - 2010
UR  - http://www.sciencedirect.com/science/journal/02680033
U6  - https://doi.org/10.1016/j.clinbiomech.2010.06.009
SN  - 0268-0033
ER  - 
TY  - JOUR
A1  - Wochatz, Monique
A1  - Tilgner, Nina
A1  - Mueller, Steffen
A1  - Rabe, Sophie
A1  - Eichler, Sarah
A1  - John, Michael
A1  - Völler, Heinz
A1  - Mayer, Frank
T1  - Reliability and validity of the Kinect V2 for the assessment of lower extremity rehabilitation exercises
JF  - Gait & posture
N2  - Research question: The purpose of this study was to evaluate the test-retest reliability of lower extremity kinematics during squat, hip abduction and lunge exercises captured by the Kinect and to evaluate the agreement to a reference 3D camera-based motion system. Methods: Twenty-one healthy individuals performed five repetitions of each lower limb exercise on two different days. Movements were simultaneously assessed by the Kinect and the reference 3D motion system. Joint angles and positions of the lower limb were calculated for sagittal and frontal plane. For the inter-session reliability and the agreement between the two systems standard error of measurement (SEM), bias with limits of agreement (LoA) and Pearson Correlation Coefficient (r) were calculated. Results: Parameters indicated varying reliability for the assessed joint angles and positions and decreasing reliability with increasing task complexity. Across all exercises, measurement deviations were shown especially for small movement amplitudes. Variability was acceptable for joint angles and positions during the squat, partially acceptable during the hip abduction and predominately inacceptable during the lunge. The agreement between systems was characterized by systematic errors. Overestimations by the Kinect were apparent for hip flexion during the squat and hip abduction/adduction during the hip abduction exercise as well as for the knee positions during the lunge. Knee and hip flexion during hip abduction and lunge were underestimated by the Kinect. Significance: The Kinect system can reliably assess lower limb joint angles and positions during simple exercises. The validity of the system is however restricted. An application in the field of early orthopedic rehabilitation without further development of post-processing techniques seems so far limited.
KW  - Reproducibility
KW  - Agreement
KW  - Markerless motion capture system
KW  - Telerehabilitation
Y1  - 2018
U6  - https://doi.org/10.1016/j.gaitpost.2019.03.020
SN  - 0966-6362
SN  - 1879-2219
VL  - 70
SP  - 330
EP  - 335
PB  - Elsevier
CY  - Clare
ER  - 
TY  - CHAP
A1  - Wochatz, Monique
A1  - Cassel, Michael
A1  - König, Niklas
A1  - Fröhlich, Katja
A1  - Mayer, Frank
T1  - Intra- and inter-observer variability of a retrospective analysis of achilles tendon ultrasound scans
T2  - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine
Y1  - 2013
SN  - 0195-9131
SN  - 1530-0315
VL  - 45
IS  - 5
SP  - 239
EP  - 239
PB  - Lippincott Williams & Wilkins
CY  - Philadelphia
ER  - 
TY  - CHAP
A1  - Intziegianni, Konstantina
A1  - Cassel, Michael
A1  - König, Niklas
A1  - Mayer, Frank
T1  - Reliability of variables defining mechanical and material properties of the achilles tendon
T2  - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine
Y1  - 2013
SN  - 0195-9131
SN  - 1530-0315
VL  - 45
IS  - 5
SP  - 238
EP  - 239
PB  - Lippincott Williams & Wilkins
CY  - Philadelphia
ER  -